S. Issifou

发表

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.

Kwaku Poku Asante, M. Tanner, K. Marsh, 2012, The New England journal of medicine.

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial.

Peter G. Kremsner, S. Agnandji, B. Lell, 2015 .

Artesunate-clindamycin versus quinine-clindamycin in the treatment of Plasmodium falciparum malaria: a randomized controlled trial.

S. Agnandji, B. Lell, A. Adegnika, 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Medical informatics in medical research - the Severe Malaria in African Children (SMAC) Network's experience.

D. Wypij, T. Taylor, S. Issifou, 2006, Methods of information in medicine.

Complexity and genetic diversity of Plasmodium falciparum infections in young children living in urban areas of Central and West Africa

C. Rogier, S. Issifou, F. Ntoumi, 2003, Parasitology Research.

High prevalence of asymptomatic Plasmodium falciparum infection in Gabonese adults.

B. Lell, S. Issifou, P. Kremsner, 2007, The American journal of tropical medicine and hygiene.

A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria

Q. Bassat, S. Issifou, P. Kremsner, 2017, BMC Medicine.

Simplified multi-organ dysfunction score predicts disability in African children with Plasmodium falciparum malaria.

S. Issifou, P. Kremsner, R. Helbok, 2006, The American journal of tropical medicine and hygiene.

The Lambaréné Organ Dysfunction Score (LODS) is a simple clinical predictor of fatal malaria in African children.

K. Bojang, K. Dietz, S. Issifou, 2009, The Journal of infectious diseases.

Markers of vascular endothelial cell damage and P. falciparum malaria: association between levels of both sE-selectin and thrombomodulin, and cytokines, hemoglobin and clinical presentation.

S. Issifou, E. Mavoungou, Anne-Marie Nkoma, 2008, European cytokine network.

Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon

S. Adjei, B. Lell, S. Issifou, 2008, Malaria Journal.

Differences in presentation of severe malaria in urban and rural Gabon.

S. Issifou, P. Kremsner, S. Krishna, 2007, The American journal of tropical medicine and hygiene.

Cellular and humoral responses to influenza in gabonese children living in rural and semi-urban areas.

B. Lell, A. Adegnika, S. Issifou, 2007, The Journal of infectious diseases.

Epidemiology of parasitic co‐infections during pregnancy in Lambaréné, Gabon

S. Agnandji, A. Adegnika, S. Issifou, 2010, Tropical medicine & international health : TM & IH.

Microscopic and sub-microscopic Plasmodium falciparum infection, but not inflammation caused by infection, is associated with low birth weight.

S. Agnandji, A. Adegnika, S. Issifou, 2006, The American journal of tropical medicine and hygiene.

Microscopic and sub-microscopic Plasmodium falciparum infection, but not inflammation caused by infection, is associated with low birth weight.

S. Agnandji, A. Adegnika, S. Issifou, 2006, The American journal of tropical medicine and hygiene.

Ibuprofen does not affect levels of tumor necrosis factor alpha and soluble tumor necrosis factor receptor types I and II in Gabonese children with uncomplicated Plasmodium falciparum malaria.

S. Issifou, E. Mavoungou, M. Missinou, 2007, European cytokine network.

Short report: evaluation of a simple and inexpensive photometric device for the measurement of hemoglobin.

S. Issifou, P. Kremsner, S. Krishna, 2004, The American journal of tropical medicine and hygiene.

Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon.

B. Cissé, B. Lell, B. Mordmüller, 2008, The Journal of infectious diseases.

Efficacy and safety of a new pediatric artesunate-mefloquine drug formulation for the treatment of uncomplicated falciparum malaria in Gabon

S. Agnandji, S. Issifou, P. Kremsner, 2010, Wiener klinische Wochenschrift.

Community-acquired pneumonia in children in Lambarene, Gabon.

S. Issifou, P. Kremsner, W. Graninger, 2008, The American journal of tropical medicine and hygiene.

Phase I randomized dose-ascending placebo-controlled trials of ferroquine - a candidate anti-malarial drug - in adults with asymptomatic Plasmodium falciparum infection

B. Lell, S. Issifou, P. Kremsner, 2011, Malaria Journal.

5-day nonobserved artesunate monotherapy for treating uncomplicated Falciparum malaria in young Gabonese children.

A. Adegnika, S. Issifou, P. Kremsner, 2005, The American journal of tropical medicine and hygiene.

Endoglin in African children with Plasmodium falciparum malaria: a novel player in severe malaria pathogenesis?

B. Lell, S. Issifou, P. Kremsner, 2009, The Journal of infectious diseases.

Reassessment of the resistance of Plasmodium falciparum to chloroquine in Gabon: implications for the validity of tests in vitro vs. in vivo.

W. Wernsdorfer, A. Adegnika, S. Issifou, 2002, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Retrospective analysis of antimicrobial resistance and bacterial spectrum of infection in Gabon, Central Africa

S. Issifou, P. Kremsner, M. Grobusch, 2013, BMC Infectious Diseases.

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.

Pedro Alonso, Trudie Lang, Bernhards Ogutu, 2011, The New England journal of medicine.

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

B. Mordmüller, S. Issifou, M. Theisen, 2012, Malaria Journal.

High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children

B. Lell, S. Issifou, P. Kremsner, 2011, Malaria Journal.

Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults.

S. Hoffman, S. Agnandji, B. Lell, 2020, Vaccine.

The use of paediatric artemisinin combinations in sub-Saharan Africa: a snapshot questionnaire survey of health care personnel

S. Agnandji, B. Lell, J. Fernandes, 2011, Malaria Journal.

First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria

S. Reed, T. Theander, B. Mordmüller, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Opposed circulating plasma levels of endothelin-1 and C-type natriuretic peptide in children with Plasmodium falciparum malaria

B. Lell, S. Issifou, P. Kremsner, 2008, Malaria Journal.

Impact of increasing consultation fees on malaria in Africa

S. Issifou, P. Kremsner, 2004, Wiener Klinische Wochenschrift.

Socio-economic status is inversely related to bed net use in Gabon

B. Lell, S. Issifou, P. Kremsner, 2008, Malaria Journal.

Surveillance of Plasmodium malariae infection among inhabitants of rural areas in Ouidah–Kpomasse–Tori Bossito health district, Benin

Euripide Avokpaho, A. Adegnika, S. Issifou, 2022, Parasitology Research.

Experimental transmission of Plasmodium malariae to Anopheles gambiae.

A. Adegnika, S. Issifou, C. Wondji, 2020, The Journal of infectious diseases.

Évaluation d'une méthode simple et rapide d'extraction de l'ADN de Plasmodium falciparum à partir de gouttes épaisses de patients gabonais.

S. Issifou, F. Ntoumi, M. Ekala, 2000 .

Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study.

T. Rolling, A. Adegnika, B. Mordmüller, 2014, The Journal of infectious diseases.

Prognostic value of circulating pigmented cells in African children with malaria.

K. Bojang, D. Wypij, C. Valim, 2009, The Journal of infectious diseases.

Assessment of a simplified method for counting leukocytic malaria pigment.

T. Taylor, B. Lell, S. Issifou, 2005, The American journal of tropical medicine and hygiene.

Pharmacokinetics of two paediatric artesunate mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon.

S. Agnandji, A. Adegnika, S. Issifou, 2007, The Journal of antimicrobial chemotherapy.

Malaria in pregnancy before and after the implementation of a national IPTp program in Gabon.

S. Agnandji, A. Adegnika, S. Issifou, 2007, The American journal of tropical medicine and hygiene.

Clinical and parasitological characteristics of puerperal malaria.

S. Agnandji, B. Lell, A. Adegnika, 2005, The Journal of infectious diseases.

Plasmodium falciparum merozoite surface protein 1 (MSP1): genotyping and humoral responses to allele-specific variants.

S. Issifou, F. Ntoumi, O. Mercereau‐Puijalon, 2002, Acta tropica.

Assessment of the anti-HBs antibody response in Beninese infants following 4 doses of HBV vaccine, including administration at birth, compared to the standard 3 doses regime; a cross-sectional survey.

Euripide Avokpaho, S. Issifou, E. Avokpaho, 2019, Vaccine.

Depressed natural killer cell cytotoxicity against Plasmodium falciparum-infected erythrocytes during first pregnancies.

S. Issifou, P. Kremsner, E. Ngou-Milama, 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials

Pedro Alonso, Marcel Tanner, David Schellenberg, 2009, The Lancet.

Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial.

S. Agnandji, B. Lell, S. Issifou, 2007, The Journal of infectious diseases.

Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women

S. Issifou, P. Kremsner, F. Ntoumi, 2004, Tropical medicine & international health : TM & IH.

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

A. Adegnika, B. Mordmüller, S. Issifou, 2017, Malaria Journal.

Interleukin-21 is associated with IgG1 and IgG3 antibodies to erythrocyte-binding antigen-175 peptide 4 of Plasmodium falciparum in Gabonese children with acute falciparum malaria.

S. Agnandji, S. Issifou, P. Kremsner, 2008, European cytokine network.

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children.

M. Christiansen, B. Mordmüller, S. Issifou, 2016, Vaccine.

The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areas.

M. Christiansen, B. Mordmüller, S. Issifou, 2013, The Journal of infectious diseases.

Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura.

S. Agnandji, A. Adegnika, B. Mordmüller, 2012, Vaccine.

Pharmacokinetics of Ferroquine, a Novel 4-Aminoquinoline, in Asymptomatic Carriers of Plasmodium falciparum Infections

C. Biot, B. Lell, S. Issifou, 2012, Antimicrobial Agents and Chemotherapy.

History and perspectives of medical research at the Albert Schweitzer Hospital in Lambaréné, Gabon

S. Agnandji, B. Lell, A. Adegnika, 2007, Wiener klinische Wochenschrift.

Short-Course Artesunate Treatment of Uncomplicated Plasmodium falciparum Malaria in Gabon

B. Lell, A. Adegnika, S. Issifou, 2003, Antimicrobial Agents and Chemotherapy.

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

K. Bojang, T. Taylor, B. Mordmüller, 2016, PLoS medicine.

Increased prevalence of intestinal helminth infection during pregnancy in a Sub-Saharan African community

S. Agnandji, A. Adegnika, S. Issifou, 2007, Wiener klinische Wochenschrift.

Randomized, Controlled, Assessor-Blind Clinical Trial To Assess the Efficacy of Single- versus Repeated-Dose Albendazole To Treat Ascaris lumbricoides, Trichuris trichiura, and Hookworm Infection

S. Agnandji, B. Lell, A. Adegnika, 2014, Antimicrobial Agents and Chemotherapy.

Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial.

Kwaku Poku Asante, M. Tanner, S. Agnandji, 2011, The Lancet. Infectious diseases.

Medical research at the Albert Schweitzer Hospital.

B. Lell, A. Adegnika, S. Issifou, 2010, Wiener klinische Wochenschrift.

Malaria antigen-mediated enhancement of interleukin-21 responses of peripheral blood mononuclear cells in African adults.

S. Agnandji, S. Issifou, P. Kremsner, 2008, Experimental parasitology.

Randomized Controlled Trial of Fosmidomycin-Clindamycin versus Sulfadoxine-Pyrimethamine in the Treatment of Plasmodium falciparum Malaria

B. Lell, S. Issifou, P. Kremsner, 2007, Antimicrobial Agents and Chemotherapy.

Fosmidomycin plus Clindamycin for Treatment of Pediatric Patients Aged 1 to 14 Years with Plasmodium falciparum Malaria

J. Wiesner, H. Jomaa, A. Adegnika, 2006, Antimicrobial Agents and Chemotherapy.

Short-Course Regimens of Artesunate-Fosmidomycin in Treatment of Uncomplicated Plasmodium falciparum Malaria

J. Wiesner, H. Jomaa, A. Adegnika, 2005, Antimicrobial Agents and Chemotherapy.

Effectiveness of quinine monotherapy for the treatment of Plasmodium falciparum infection in pregnant women in Lambaréné, Gabon.

S. Agnandji, A. Adegnika, S. Issifou, 2005, The American journal of tropical medicine and hygiene.

Fosmidomycin for malaria

Jochen Wiesner, J. Wiesner, H. Jomaa, 2002, The Lancet.

Influence of carriage of hemoglobin AS and the Fc gamma receptor IIa-R131 allele on levels of immunoglobulin G2 antibodies to Plasmodium falciparum merozoite antigens in Gabonese children.

B. Lell, S. Issifou, P. Kremsner, 2005, The Journal of infectious diseases.

Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae.

B. Mordmüller, S. Issifou, K. Moutairou, 2017, Vaccine.

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

B. Mordmüller, S. Issifou, M. Theisen, 2012, Malaria Journal.

A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children

R. Noor, B. Mordmüller, S. Issifou, 2011, PloS one.

Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon.

R. Noor, W. Kilama, B. Mordmüller, 2010, Vaccine.

Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malaria.

H. Jomaa, A. Adegnika, S. Issifou, 2004, The Journal of infectious diseases.

Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study

A. Adegnika, B. Mordmüller, S. Issifou, 2015, BMC Medicine.

Matrix metalloproteinases and their tissue inhibitors (TIMPs) in Plasmodium falciparum malaria: serum levels of TIMP-1 are associated with disease severity.

B. Lell, S. Issifou, P. Kremsner, 2008, The Journal of infectious diseases.

No variation in the prevalence of point mutations in the Pfcrt and Pfmdr1 genes in isolates from Gabonese patients with uncomplicated or severe Plasmodium falciparum malaria

S. Issifou, P. Kremsner, F. Ntoumi, 2006, Parasitology Research.

Antibodies to Plasmodium falciparum Rifin Proteins Are Associated with Rapid Parasite Clearance and Asymptomatic Infections

K. Dietz, S. Issifou, P. Kremsner, 2003, Infection and Immunity.

Persistent Plasmodium falciparum Infection in Women With an Intent to Become Pregnant as a Risk Factor for Pregnancy-associated Malaria

S. Issifou, P. Deloron, A. Salanti, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Lactic acidosis in Gabonese children with severe malaria is unrelated to dehydration.

S. Issifou, P. Kremsner, J. Jarvis, 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Placental malaria increases malaria risk in the first 30 months of life.

S. Agnandji, B. Lell, A. Adegnika, 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

A pilot study on cytotoxic T lymphocyte-4 gene polymorphisms in urinary schistosomiasis.

B. Lell, A. Adegnika, S. Issifou, 2012, Genetic testing and molecular biomarkers.

Pregnancy-associated malaria affects toll-like receptor ligand-induced cytokine responses in cord blood.

S. Agnandji, A. Adegnika, S. Issifou, 2008, The Journal of infectious diseases.

Fosmidomycin-clindamycin for Plasmodium falciparum Infections in African children.

J. Wiesner, H. Jomaa, A. Adegnika, 2004, The Journal of infectious diseases.

Epidemiology and population structure of Staphylococcus aureus in various population groups from a rural and semi urban area in Gabon, Central Africa.

B. Lell, J. Fernandes, A. Adegnika, 2012, Acta tropica.

A simplified intravenous artesunate regimen for severe malaria.

J. Simpson, T. Taylor, B. Mordmüller, 2012, The Journal of infectious diseases.

Evaluation of the safety and immunogenicity of the RTS,S/AS01E malaria candidate vaccine when integrated in the expanded program of immunization.

Kwaku Poku Asante, M. Tanner, M. Demoitié, 2010, The Journal of infectious diseases.

[No influence of season of transmission nor age of patients on the complexity and genetic diversity of Plasmodium falciparum infection in Cotonou, Benin].

S. Issifou, F. Ntoumi, A. Sanni, 2001, Bulletin de la Société de Pathologie Exotique.

No influence of the transmission season on genetic diversity and complexity of infections in Plasmodium falciparum isolates from Benin.

S. Issifou, F. Ntoumi, A. Sanni, 2001, African journal of medicine and medical sciences.

Reasons for non-adherence to vaccination at mother and child care clinics (MCCs) in Lambaréné, Gabon.

B. Lell, S. Issifou, P. Kremsner, 2009, Vaccine.

Population Structure of Staphylococcus aureus from Remote African Babongo Pygmies

A. Friedrich, S. Issifou, P. Kremsner, 2011, PLoS neglected tropical diseases.

Antipyretic effect of ibuprofen in Gabonese children with uncomplicated falciparum malaria: a randomized, double-blind, placebo-controlled trial

B. Lell, S. Issifou, P. Kremsner, 2008, Malaria Journal.

Haplotype specific-sequencing reveals MBL2 association with asymptomatic Plasmodium falciparum infection

M. Pedroso, B. Lell, S. Issifou, 2009, Malaria Journal.

Malaria control and elimination in sub-Saharan Africa: data from antenatal care centres.

S. Issifou, M. Accrombessi, 2019, The Lancet. Global health.

Surveillance of Plasmodium malariae infection among inhabitants of rural areas in Ouidah–Kpomasse–Tori Bossito health district, Benin

Euripide Avokpaho, A. Adegnika, S. Issifou, 2022, Parasitology research.

The risk to import ESBL-producing Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon

A. Mellmann, S. Issifou, P. Kremsner, 2014, BMC Microbiology.

CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel

A. Adegnika, S. Issifou, P. Kremsner, 2015, PLoS neglected tropical diseases.

Short course of quinine plus a single dose of sulfadoxine/pyrimethamine for Plasmodium falciparum malaria

S. Issifou, P. Kremsner, M. Missinou, 2006, Wiener klinische Wochenschrift.

Cellular and humoral responses to tetanus vaccination in Gabonese children.

H. Uh, B. Lell, A. Adegnika, 2008, Vaccine.

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

A. Adegnika, B. Mordmüller, S. Issifou, 2017, Malaria Journal.

Severe malarial anemia associated with increased soluble Fas ligand (sFasL) concentrations in Gabonese children.

S. Issifou, P. Kremsner, F. Ntoumi, 2003, European Cytokine Network.

In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon.

B. Mordmüller, S. Issifou, P. Kremsner, 2010, International journal of antimicrobial agents.

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon

M. Demoitié, S. Agnandji, B. Lell, 2009, PloS one.

Malaria and asymptomatic parasitaemia in Gabonese infants under the age of 3 months.

S. Issifou, P. Kremsner, M. Grobusch, 2005, Acta tropica.

Delayed parasite elimination in human infections treated with clindamycin parallels 'delayed death' of Plasmodium falciparum in vitro.

J. Wiesner, H. Jomaa, S. Issifou, 2007, International journal for parasitology.

Severe malaria in a splenectomised Gabonese woman

S. Issifou, P. Kremsner, M. Grobusch, 2003, Wiener Klinische Wochenschrift.

The Lambaréné Organ Dysfunction Score (LODS) is a simple clinical predictor of fatal malaria in African children.

K. Bojang, K. Dietz, S. Issifou, 2009, The Journal of infectious diseases.

Short report: Piloting paperless data entry for clinical research in Africa.

David Wypij, D. Wypij, T. Taylor, 2005, The American journal of tropical medicine and hygiene.

Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial.

S. Agnandji, B. Lell, S. Issifou, 2007, The Journal of infectious diseases.

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children.

M. Christiansen, B. Mordmüller, S. Issifou, 2016, Vaccine.