G. Ofek

发表

Elicitation of structure-specific antibodies by epitope scaffolds

D. Baker, R. Wyatt, W. Schief, 2010, Proceedings of the National Academy of Sciences.

Structure and Mechanistic Analysis of the Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5 in Complex with Its gp41 Epitope

Peter D. Kwong, John R. Mascola, Hermann Katinger, 2004, Journal of Virology.

Distribution and three-dimensional structure of AIDS virus envelope spikes

J. Lifson, J. Bess, G. Ofek, 2006, Nature.

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Jamie K. Scott, H. Liao, B. Haynes, 2011, Journal of Virology.

Crystal structure , conformational fixation , and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016 .

Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains

Baoshan Zhang, Peter D. Kwong, John R. Mascola, 2013, Proceedings of the National Academy of Sciences.

Enhancing protein crystallization through precipitant synergy.

T. Zhou, P. Kwong, G. Ofek, 2003, Structure.

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

Jonathan R. McDaniel, T. Kepler, B. Korber, 2017, Science Immunology.

Expanding the breadth of an HIV-1 vaccine

G. Ofek, R. Diskin, 2014, Science.

Somatic Populations of PGT135–137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

J. Mullikin, J. Mascola, D. Burton, 2012, Front. Microbio..

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Cinque S. Soto, J. Mullikin, B. Haynes, 2016, PloS one.

Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop

Cinque S. Soto, Nydia van Dyk, N. V. Dyk, 2018, Nature Communications.

Structural Features of Antibody-Peptide Recognition

B. Pierce, G. Ofek, Rui Yin, 2022, Frontiers in Immunology.

Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies

Jamie K. Scott, H. Liao, B. Haynes, 2013, Journal of Virology.

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

M. Prausnitz, G. Ofek, T. Fuerst, 2022, Journal of functional biomaterials.

Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

Gwo-Yu Chuang, Wei Shi, Ivelin S Georgiev, 2014, The Journal of Immunology.

Reverted to Germline with Ig-Framework Regions Substantially HIV-1 with High Breadth and Potency Even Antibodies VRC01 and 10E8 Neutralize

J. Mascola, G. Chuang, G. Nabel, 2014 .

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

B. Haynes, D. Ho, J. Mascola, 2016, Journal of Virology.

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Baoshan Zhang, Peter D. Kwong, John R. Mascola, 2012, Nature.

Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region

J. Mascola, R. Wyatt, G. Nabel, 2009, Journal of Virology.

Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

E. Reinherz, G. Wagner, P. Kwong, 2011, Nature Structural &Molecular Biology.

, Epitope 1 Antibody 2 F 5 in Complex with Its gp 41 Anti-Human Immunodeficiency Virus Type Structure and Mechanistic Analysis of the

J. Mascola, H. Katinger, R. Wyatt, 2004 .

Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization

Tongqing Zhou, Lynn Morris, Gwo-Yu Chuang, 2013, Science.

Structure and immune recognition of trimeric prefusion HIV-1 Env

Tongqing Zhou, Yongping Yang, Baoshan Zhang, 2014, Nature.

Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41

H. Liao, Laura L. Sutherland, B. Haynes, 2011, PloS one.

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies

I. Wilson, P. Kwong, G. Ofek, 2014, Nature Structural &Molecular Biology.

Structural Biology and the Design of Effective Vaccines for HIV-1 and Other Viruses

M. Sastry, G. Nabel, P. Acharya, 2010, National Institute of Allergy and Infectious Diseases, NIH.

Transplanting Supersites of HIV-1 Vulnerability

Cinque S. Soto, D. Burton, M. Connors, 2014, PloS one.

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

J. Mascola, D. Dimitrov, G. Chuang, 2013, Journal of Virology.

HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.

Jerome H. Kim, P. Zhang, E. Go, 2020, JCI insight.

Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant

D. Baker, R. Wyatt, W. Schief, 2011, PloS one.

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

James B. Munro, Daniel S. Terry, Cinque S. Soto, 2015, Nature Structural &Molecular Biology.

Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies

I. Wilson, P. Kwong, G. Ofek, 2014, Nature Structural &Molecular Biology.

Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers.

M. Byrne, J. Sturis, E. van Cauter, 1994, The American journal of physiology.

Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans

K. Janowska, G. Ofek, K. Wiehe, 2024, Cell.