I. J. van der Klei

发表

Moonlighting proteins: an intriguing mode of multitasking.

Daphne H. E. W. Huberts, I. J. van der Klei, Daphne Huberts, 2010, Biochimica et Biophysica Acta.

Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat—Store ’em Up or Burn ’em Down

S. Kohlwein, I. J. van der Klei, M. Veenhuis, 2013, Genetics.

Hansenula polymorpha Swi1p and Snf2p are essential for methanol utilisation.

Kantcho Lahtchev, Marten Veenhuis, I. J. van der Klei, 2004, FEMS yeast research.

Assembly of alcohol oxidase in the cytosol of a peroxisome‐deficient mutant of Hansenula polymorpha—properties of the protein and architecture of the crystals

I. J. van der Klei, M. Veenhuis, G. Sulter, 1991 .

Novel genetic tools for Hansenula polymorpha.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2012, FEMS yeast research.

Penicillium chrysogenum Pex14/17p – a novel component of the peroxisomal membrane that is important for penicillin production

I. J. van der Klei, M. Veenhuis, J. Kiel, 2010, The FEBS journal.

Adaptation of Hansenula polymorpha to methanol: a transcriptome analysis

Anne de Jong, Oscar P Kuipers, Marten Veenhuis, 2010, BMC Genomics.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

John L Cleveland, Masaaki Komatsu, Katsuhiko Kitamoto, 2008, Autophagy.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

A unified nomenclature for peroxisome biogenesis factors

H. Moser, D. Valle, H. Tabak, 1996, The Journal of cell biology.

Peroxisome proliferation in Hansenula polymorpha requires Dnm1p which mediates fission but not de novo formation.

I. J. van der Klei, M. Veenhuis, R. Saraya, 2008, Biochimica et biophysica acta.

Autophagy: principles and significance in health and disease.

Virginia Todde, Marten Veenhuis, I. J. van der Klei, 2009, Biochimica et biophysica acta.

ATG Genes Involved in Non-Selective Autophagy are Conserved from Yeast to Man, but the Selective Cvt and Pexophagy Pathways also Require Organism-Specific Genes

Marten Veenhuis, I. J. van der Klei, M. Veenhuis, 2007, Autophagy.

Peroxisome Biogenesis and Selective Degradation Converge at Pex14p*

I. J. van der Klei, M. Veenhuis, J. Kiel, 2001, The Journal of Biological Chemistry.

Macropexophagy in Hansenula polymorpha: facts and views

I. J. van der Klei, M. Veenhuis, J. Kiel, 2003, FEBS letters.

Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains.

Bettina Warscheid, Thomas Becker, Silke Oeljeklaus, 2012, Journal of molecular biology.

Overproduction of BiP negatively affects the secretion of Aspergillus niger glucose oxidase by the yeast Hansenula polymorpha

C. Hollenberg, I. J. van der Klei, M. Veenhuis, 2002, Applied Microbiology and Biotechnology.

Peroxisome assembly in yeast

I. J. van der Klei, M. Veenhuis, J. Kiel, 2003, Microscopy research and technique.

Peroxisome biogenesis and degradation in yeast: A structure/function analysis

I. J. van der Klei, M. Veenhuis, F. Salomons, 2000, Microscopy research and technique.

The ubiquitin‐conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery

J. Cregg, I. J. van der Klei, M. Veenhuis, 1998, The EMBO journal.

Characterization of Aspergillus nidulans peroxisomes by immunoelectron microscopy

I. J. van der Klei, M. Veenhuis, S. Valenciano, 1998, Archives of microbiology.

Deviant Pex3p Levels affect Normal Peroxisome Formation in Hansenula polymorpha: High Steady‐state Levels of the Protein fully Abolish Matrix Protein Import

K. Faber, I. J. van der Klei, M. Veenhuis, 1997, Yeast.

The Hansenula polymorpha PER3 Gene Is Essential for the Import of PTS1 Proteins into the Peroxisomal Matrix (*)

E. G. Vrieling, H. Waterham, J. Cregg, 1995, The Journal of Biological Chemistry.

Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan

I. J. van der Klei, S. Lefevre, Sanjeev Kumar, 2015, Cell cycle.

Divide et Impera: The Dictum of Peroxisomes

Marten Veenhuis, I. J. van der Klei, M. Veenhuis, 2010, Traffic.

Membrane curvature during peroxisome fission requires Pex11

I. J. van der Klei, M. Veenhuis, J. Kiel, 2010, The EMBO journal.

Peroxisomes: membrane events accompanying peroxisome proliferation.

I. J. van der Klei, M. Veenhuis, Łukasz Opaliński, 2011, The international journal of biochemistry & cell biology.

Peroxisome Fission is Associated with Reorganization of Specific Membrane Proteins

I. J. van der Klei, M. Veenhuis, Shirisha Nagotu, 2011, Traffic.

Peroxisomes as dynamic organelles: peroxisome abundance in yeast

I. J. van der Klei, M. Veenhuis, R. Saraya, 2010, The FEBS journal.

Reassembly of peroxisomes in Hansenula polymorpha pex3 cells on reintroduction of Pex3p involves the nuclear envelope.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2006, FEMS yeast research.

PEX Genes in Fungal Genomes: Common, Rare or Redundant

I. J. van der Klei, M. Veenhuis, J. Kiel, 2006, Traffic.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2006, Journal of Cell Science.

In the yeast Hansenula polymorpha, peroxisome formation from the ER is independent of Pex19p, but involves the function of p24 proteins.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2006, FEMS yeast research.

Peroxisome Fission in Hansenula polymorpha Requires Mdv1 and Fis1, Two Proteins Also Involved in Mitochondrial Fission

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2008, Traffic.

Assembly of the Mitochondrial Cristae Organizer Mic10 Is Regulated by Mic26-Mic27 Antagonism and Cardiolipin.

I. J. van der Klei, N. Pfanner, M. van der Laan, 2018, Journal of molecular biology.

The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p

I. J. van der Klei, V. Titorenko, M. Veenhuis, 1999, Yeast.

A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy

J. Cregg, I. J. van der Klei, M. Veenhuis, 1999, Current Genetics.

The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics.

J. Pronk, J. Daran, A. K. Gombert, 2010, Fungal genetics and biology : FG & B.

Pex24 and Pex32 tether peroxisomes to the ER for organelle biogenesis, positioning and segregation

Arjen M. Krikken, N. Bordin, D. Devos, 2020, bioRxiv.

Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast

Arjen M. Krikken, N. Bordin, D. Devos, 2020, Journal of Cell Science.

Atg8 is Essential for Macropexophagy in Hansenula polymorpha

Arjen M. Krikken, I. J. van der Klei, Iryna Monastyrska, 2005, Traffic.

A Peroxisomal Lon Protease and Peroxisome Degradation by Autophagy Play Key Roles in Vitality of Hansenula polymorpha Cells

I. J. van der Klei, M. Veenhuis, S. Jourdan, 2007, Autophagy.

How Shall I Eat Thee?

P. Seglen, D. Klionsky, I. J. van der Klei, 2007, Autophagy.

Peroxicretion: a novel secretion pathway in the eukaryotic cell

M. Akeroyd, J. D. de Winde, I. J. van der Klei, 2009, BMC biotechnology.

Central role of Mic10 in the mitochondrial contact site and cristae organizing system.

W. Kühlbrandt, K. Davies, I. J. van der Klei, 2015, Cell metabolism.

Uniform nomenclature for the mitochondrial contact site and cristae organizing system

Sang Ki Park, Susan S. Taylor, J. Weissman, 2014, The Journal of cell biology.

Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin-proteasome system.

I. J. van der Klei, Chris Williams, 2013, Biochemical and biophysical research communications.

Removal of Pex3p Is an Important Initial Stage in Selective Peroxisome Degradation in Hansenula polymorpha *

I. J. van der Klei, M. Veenhuis, J. Kiel, 2002, The Journal of Biological Chemistry.

Lumenal peroxisomal protein aggregates are removed by concerted fission and autophagy events

I. J. van der Klei, M. Veenhuis, Rinse de Boer, 2013, Autophagy.

Improving penicillin biosynthesis in Penicillium chrysogenum by glyoxalase overproduction.

I. J. van der Klei, M. Veenhuis, C. Scheckhuber, 2013, Metabolic engineering.

Characterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase Y

I. J. van der Klei, M. Veenhuis, J. Kiel, 1999, Yeast.

Characterization of the Hansenula polymorpha CPY gene encoding carboxypeptidase Y

I. J. van der Klei, M. Veenhuis, J. Kiel, 1999 .

Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

B. Habenstein, I. J. van der Klei, M. Bramkamp, 2020, eLife.

Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

I. J. van der Klei, M. Bramkamp, A. Zielińska, 2019, bioRxiv.

New yeast expression platforms based on methylotrophic Hansenula polymorpha and Pichia pastoris and on dimorphic Arxula adeninivorans and Yarrowia lipolytica - a comparison.

J. Cregg, I. J. van der Klei, G. Kunze, 2005, FEMS yeast research.

Hansenula Polymorpha Vac8: A Vacuolar Membrane Protein Required for Vacuole Inheritance and Nucleus-Vacuole Junction Formation

I. J. van der Klei, J. Wróblewska, Rinse de Boer, 2020 .

Damaged peroxisomes are subject to rapid autophagic degradation in the yeast Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, Tim van Zutphen, 2011, Autophagy.

Pexophagy in Hansenula polymorpha.

I. J. van der Klei, J. Kiel, Tim van Zutphen, 2008, Methods in enzymology.

Brefeldin A interferes with peroxisomal protein sorting in the yeast Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, W. Harder, 1997, FEBS letters.

Proteins involved in microbody biogenesis and degradation in Aspergillus nidulans.

I. J. van der Klei, J. Kiel, 2009, Fungal genetics and biology : FG & B.

Overproduction of translation elongation factor 1-alpha (eEF1A) suppresses the peroxisome biogenesis defect in a Hansenula polymorpha pex3 mutant via translational read-through.

I. J. van der Klei, V. Titorenko, M. Veenhuis, 2007, FEMS yeast research.

The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space.

A. Gruhler, W. Neupert, R. Stuart, 1994, European journal of biochemistry.

Routing of Hansenula polymorpha alcohol oxidase: an alternative peroxisomal protein-sorting machinery.

I. J. van der Klei, M. Veenhuis, R. van Dijk, 2003, Molecular biology of the cell.

Microautophagy and macropexophagy may occur simultaneously in Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, J. Kiel, 2004, FEBS letters.

A morphological view on mitochondrial protein targeting

W. Neupert, I. J. van der Klei, M. Veenhuis, 1994, Microscopy research and technique.

The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission

Arjen M. Krikken, M. Schrader, I. J. van der Klei, 2015, Proceedings of the National Academy of Sciences.

A critical reflection on the principles of peroxisome formation in yeast

I. J. van der Klei, M. Veenhuis, 2014, Front. Physiol..

Yeast peroxisomes: function and biogenesis of a versatile cell organelle.

I. J. van der Klei, M. Veenhuis, I. Klei, 1997, Trends in microbiology.

Impaired biosynthesis of the non-bilayer lipids phosphatidylethanolamine or cardiolipin does not affect peroxisome biogenesis and proliferation in Saccharomyces cerevisiae.

I. J. van der Klei, Adam Kawalek, C. Jagadeesan, 2016, Biochemical and biophysical research communications.

Stress exposure results in increased peroxisomal levels of yeast Pnc1 and Gpd1, which are imported via a piggy-backing mechanism.

I. J. van der Klei, Chris Williams, Sanjeev Kumar, 2016, Biochimica et biophysica acta.

Activation of a peroxisomal Pichia pastoris D-amino acid oxidase, which uses d-alanine as a preferred substrate, depends on pyruvate carboxylase.

I. J. van der Klei, M. Veenhuis, Richard J. S. Baerends, 2010, FEMS yeast research.

Preserving organelle vitality: peroxisomal quality control mechanisms in yeast.

I. J. van der Klei, J. Kiel, E. B. Aksam, 2009, FEMS yeast research.

Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2007, FEMS yeast research.

Evolving models for peroxisome biogenesis

I. J. van der Klei, M. Veenhuis, R. Erdmann, 2014, Current opinion in cell biology.

Absence of the peroxiredoxin Pmp20 causes peroxisomal protein leakage and necrotic cell death.

H. Jungwirth, S. Kohlwein, I. J. van der Klei, 2008, Free radical biology & medicine.

The Hansenula polymorpha per6 mutant is affected in two adjacent genes which encode dihydroxyacetone kinase and a novel protein, Pak1p, involved in peroxisome integrity

I. J. van der Klei, M. Veenhuis, J. Kiel, 1998, Current Genetics.

De Novo Peroxisome Biogenesis in Penicillium Chrysogenum Is Not Dependent on the Pex11 Family Members or Pex16

I. J. van der Klei, M. Veenhuis, J. Kiel, 2012, PloS one.

The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi

I. J. van der Klei, M. Veenhuis, Łukasz Opaliński, 2011, Biotechnology Letters.

Cold-inducible selective degradation of peroxisomes in Hansenula polymorpha.

I. J. van der Klei, M. Veenhuis, K. Knoops, 2004, FEMS yeast research.

The Hansenula polymorpha PER9 Gene Encodes a Peroxisomal Membrane Protein Essential for Peroxisome Assembly and Integrity (*)

K. Faber, J. Cregg, I. J. van der Klei, 1996, The Journal of Biological Chemistry.

Ubiquitin, a central component of selective cytoplasmic proteolysis, is linked to proteins residing at the locus of non‐selective proteolysis, the vacuole

I. J. van der Klei, M. Veenhuis, D. Wolf, 1992, FEBS letters.

Glucose-induced and nitrogen-starvation-induced peroxisome degradation are distinct processes in Hansenula polymorpha that involve both common and unique genes.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2001, FEMS yeast research.

A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria

W. Neupert, I. J. van der Klei, F. Nargang, 1994, The Journal of cell biology.

Obstruction of polyubiquitination affects PTS1 peroxisomal matrix protein import.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2005, Biochimica et biophysica acta.

Protein translocation machineries: how organelles bring in matrix proteins.

I. J. van der Klei, M. Veenhuis, Katja Gunkel, 2005, FEMS yeast research.

Yeast peroxisomes: How are they formed and how do they grow?

I. J. van der Klei, Arman Akşit, 2018, The international journal of biochemistry & cell biology.

Yeast Vps13 is Crucial for Peroxisome Expansion in Cells With Reduced Peroxisome-ER Contact Sites

Arjen M. Krikken, I. J. van der Klei, Rinse de Boer, 2022, Frontiers in Cell and Developmental Biology.

Peroxisome development in yeast is associated with the formation of Pex3-dependent peroxisome-vacuole contact sites.

Arjen M. Krikken, I. J. van der Klei, W. Yuan, 2019, Biochimica et biophysica acta. Molecular cell research.

Novel Peroxisome–Vacuole Contacts in Yeast

I. J. van der Klei, Huala Wu, 2019, Contact.

Peroxisome reintroduction in Hansenula polymorpha requires Pex25 and Rho1

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2015, The Journal of cell biology.

Peroxisome reintroduction in Hansenula polymorpha requires Pex25 and Rho1

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2011, The Journal of cell biology.

Atg21p is essential for macropexophagy and microautophagy in the yeast Hansenula polymorpha

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2004, FEBS letters.

A novel platform for the production of nonhydroxylated gelatins based on the methylotrophic yeast Hansenula polymorpha.

I. J. van der Klei, M. Veenhuis, T. Geerlings, 2007, FEMS yeast research.

Peroxisomes: flexible and dynamic organelles.

I. J. van der Klei, M. Veenhuis, Marten Veenhuis, 2002, Current opinion in cell biology.

The glyoxysomal and plastid molecular chaperones (70-kDa heat shock protein) of watermelon cotyledons are encoded by a single gene.

I. J. van der Klei, F. Lottspeich, M. Veenhuis, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Deviant Pex3p Levels affect Normal Peroxisome Formation in Hansenula polymorpha: A Sharp Increase of the Protein Level Induces the Proliferation of Numerous, Small Protein‐import Competent Peroxisomes

I. J. van der Klei, M. Veenhuis, J. Kiel, 1997, Yeast.

The relevance of the non-canonical PTS1 of peroxisomal catalase.

I. J. van der Klei, M. Veenhuis, Chris Williams, 2012, Biochimica et biophysica acta.

Peroxisomal quality control mechanisms.

I. J. van der Klei, Sanjeev Kumar, Adam Kawałek, 2014, Current opinion in microbiology.

Biosynthesis of active pharmaceuticals: β-lactam biosynthesis in filamentous fungi

I. J. van der Klei, J. Kiel, M. Berg, 2010, Biotechnology & genetic engineering reviews.

Peroxisomal Proteostasis Involves a Lon Family Protein That Functions as Protease and Chaperone*

I. J. van der Klei, A. Kikhney, M. Veenhuis, 2012, The Journal of Biological Chemistry.

Pexophagy: Autophagic Degradation of Peroxisomes

I. J. van der Klei, J. Kiel, Y. Sakai, 2022 .

Biosynthesis and assembly of alcohol oxidase, a peroxisomal matrix protein in methylotrophic yeasts: A review

I. J. van der Klei, M. Veenhuis, W. Harder, 1991, Yeast.

Alcohol oxidase from Hansenula polymorpha CBS 4732.

I. J. van der Klei, L. Bystrykh, W. Harder, 1990, Methods in enzymology.

An Engineered Yeast Efficiently Secreting Penicillin

Marten Veenhuis, Reza M. Seifar, Rutger D. Douma, 2009, PloS one.

Isolation and properties of genetically defined strains of the methylotrophic yeast Hansenula polymorpha CBS4732

I. J. van der Klei, M. Veenhuis, K. Lahtchev, 2002, Archives of Microbiology.

Hansenula polymorpha Pex3p Is a Peripheral Component of the Peroxisomal Membrane*

Arjen M. Krikken, K. Faber, I. J. van der Klei, 2002, The Journal of Biological Chemistry.

The 2008 update of the Aspergillus nidulans genome annotation: a community effort.

Bernard Henrissat, Jibin Sun, Masashi Kato, 2009, Fungal genetics and biology : FG & B.

Mitofilin complexes: conserved organizers of mitochondrial membrane architecture

I. J. van der Klei, N. Pfanner, M. van der Laan, 2012, Biological chemistry.

Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1

I. J. van der Klei, M. Fromont-Racine, Lisa Kappel, 2007, Molecular and Cellular Biology.

Sorting and function of peroxisomal membrane proteins.

K. Faber, I. J. van der Klei, M. Veenhuis, 2000, FEMS microbiology reviews.

The Impact of Peroxisomes on Cellular Aging and Death

I. J. van der Klei, M. Veenhuis, C. Scheckhuber, 2012, Front. Oncol..

A Stretch of Positively Charged Amino Acids at the N Terminus ofHansenula polymorpha Pex3p Is Involved in Incorporation of the Protein into the Peroxisomal Membrane*

K. Faber, I. J. van der Klei, M. Veenhuis, 2000, The Journal of Biological Chemistry.

The versatility of peroxisome function in filamentous fungi.

I. J. van der Klei, M. Veenhuis, 2013, Sub-cellular biochemistry.

Preperoxisomal vesicles can form in the absence of Pex3

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2014, The Journal of cell biology.

Tools for genetic engineering of the yeast Hansenula polymorpha.

I. J. van der Klei, M. Veenhuis, R. Saraya, 2014, Methods in molecular biology.

The moonlighting function of pyruvate carboxylase resides in the non-catalytic end of the TIM barrel.

G. Vriend, Daphne H. E. W. Huberts, I. J. van der Klei, 2010, Biochimica et biophysica acta.

The transcarboxylase domain of pyruvate carboxylase is essential for assembly of the peroxisomal flavoenzyme alcohol oxidase.

I. J. van der Klei, M. Veenhuis, Paulina Z Ozimek, 2007, FEMS yeast research.

Redirection of peroxisomal alcohol oxidase of Hansenula polymorpha to the secretory pathway.

I. J. van der Klei, M. Veenhuis, M. van der Heide, 2007, FEMS yeast research.

Hansenula polymorpha Vam7p is required for macropexophagy.

I. J. van der Klei, Iryna Monastyrska, M. Veenhuis, 2005, FEMS yeast research.

Hansenula polymorpha Pex20p is an oligomer that binds the peroxisomal targeting signal 2 (PTS2)

I. J. van der Klei, Dongyuan Wang, Marleen Otzen, 2005, Journal of Cell Science.

Hansenula polymorpha Pex19p Is Essential for the Formation of Functional Peroxisomal Membranes*

I. J. van der Klei, M. Veenhuis, Richard J. S. Baerends, 2004, Journal of Biological Chemistry.

The Hansenula polymorpha PEX14 gene encodes a novel peroxisomal membrane protein essential for peroxisome biogenesis

J. Cregg, I. J. van der Klei, M. Veenhuis, 1997, The EMBO journal.

Isolation and characterization of peroxisomal protein import (Pim−) mutants of Hansenula polymorpha

H. Waterham, I. J. van der Klei, V. Titorenko, 1992 .

Protein targeting to yeast peroxisomes.

I. J. van der Klei, M. Veenhuis, 2007, Methods in molecular biology.

Autophagy Deficiency Promotes β-Lactam Production in Penicillium chrysogenum

Marten Veenhuis, Jan A. K. W. Kiel, Roel A. L. Bovenberg, 2010, Applied and Environmental Microbiology.

Peroxisomes Are Required for Efficient Penicillin Biosynthesis in Penicillium chrysogenum

Jan A. K. W. Kiel, Roel A. L. Bovenberg, I. J. van der Klei, 2010, Applied and Environmental Microbiology.

A comparative study of peroxisomal structures in Hansenula polymorpha pex mutants.

I. J. van der Klei, M. Veenhuis, M. Komori, 2007, FEMS yeast research.

Overproduction of a single protein, Pc-Pex11p, results in 2-fold enhanced penicillin production by Penicillium chrysogenum.

Marten Veenhuis, I. J. van der Klei, M. Veenhuis, 2005, Fungal genetics and biology : FG & B.

Overproduction of Pex5p Stimulates Import of Alcohol Oxidase and Dihydroxyacetone Synthase in a Hansenula polymorpha pex14Null Mutant*

K. Faber, I. J. van der Klei, M. Veenhuis, 2000, The Journal of Biological Chemistry.

Structure–function analysis of the ER-peroxisome contact site protein Pex32

I. J. van der Klei, Fei Wu, 2022, Frontiers in Cell and Developmental Biology.

Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins.

M. Schuldiner, E. Zalckvar, I. J. van der Klei, 2017, Biochimica et biophysica acta. Molecular cell research.

The birth of yeast peroxisomes.

I. J. van der Klei, M. Veenhuis, W. Yuan, 2016, Biochimica et biophysica acta.

Yeast pex1 cells contain peroxisomal ghosts that import matrix proteins upon reintroduction of Pex1

I. J. van der Klei, K. Knoops, A. Kram, 2015, The Journal of cell biology.

A conserved function for Inp2 in peroxisome inheritance.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2010, Biochimica et biophysica acta.

Hansenula polymorpha pex11 cells are affected in peroxisome retention

Marten Veenhuis, Arjen M. Krikken, I. J. van der Klei, 2009, The FEBS journal.

Transcriptional Down-regulation of Peroxisome Numbers Affects Selective Peroxisome Degradation in Hansenula polymorpha*

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2003, Journal of Biological Chemistry.

Import of assembled PTS1 proteins into peroxisomes of the yeast Hansenula polymorpha: yes and no!

K. Faber, I. J. van der Klei, M. Veenhuis, 2002, Biochimica et biophysica acta.

Mutational analysis of the N-terminal topogenic signal of watermelon glyoxysomal malate dehydrogenase using the heterologous host Hansenula polymorpha.

K. Faber, I. J. van der Klei, M. Veenhuis, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Yeast and filamentous fungi as model organisms in microbody research.

I. J. van der Klei, M. Veenhuis, 2006, Biochimica et biophysica acta.

Alcohol oxidase: a complex peroxisomal, oligomeric flavoprotein.

I. J. van der Klei, M. Veenhuis, Paulina Z Ozimek, 2005, FEMS yeast research.

Hansenula polymorpha Tup1p is important for peroxisome degradation.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2004, FEMS yeast research.

Selective peroxisome degradation in Yarrowia lipolytica after a shift of cells from acetate/oleate/ethylamine into glucose/ammonium sulfate‐containing media

I. J. van der Klei, G. Barth, M. Veenhuis, 1999, FEBS letters.

Peroxisomal remnants in peroxisome‐deficient mutants of the yeast Hansenula polymorha

I. J. van der Klei, M. Veenhuis, J. Kiel, 1996 .

Selective inactivation of alcohol oxidase in two peroxisome‐deficient mutants of the yeast Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, W. Harder, 1991, Yeast.

Peroxisomal remnants in peroxisome-deficient mutants of the yeast Hansenula polymorpha [corrected].

I. J. van der Klei, M. Veenhuis, J. Kiel, 1996, FEBS Letters.

Watermelon glyoxysomal malate dehydrogenase is sorted to peroxisomes of the methylotrophic yeast, Hansenula polymorpha

K. Faber, I. J. van der Klei, M. Veenhuis, 1993, FEBS letters.

Conformational transitions accompanying oligomerization of yeast alcohol oxidase, a peroxisomal flavoenzyme.

G. Vriend, I. J. van der Klei, A. Visser, 1999, Biochemistry.

Flavin adenine dinucleotide binding is the crucial step in alcohol oxidase assembly in the yeast Hansenula polymorpha

I. J. van der Klei, V. Titorenko, M. Veenhuis, 1996, Yeast.

Assembly of alcohol oxidase in peroxisomes of the yeast Hansenula polymorpha requires the cofactor flavin adenine dinucleotide.

I. J. van der Klei, V. Titorenko, M. Veenhuis, 1994, Molecular biology of the cell.

p24 proteins play a role in peroxisome proliferation in yeast

I. J. van der Klei, Marleen Otzen, E. Kurbatova, 2009, FEBS letters.

Physical Interactions of the Peroxisomal Targeting Signal 1 Receptor Pex5p, Studied by Fluorescence Correlation Spectroscopy*

I. J. van der Klei, M. Veenhuis, Dongyuan Wang, 2003, Journal of Biological Chemistry.

Isolation of mutants of Hansenula polymorpha defective in the assembly of octameric alcohol oxidase.

I. J. van der Klei, M. Veenhuis, R. van Dijk, 2002, FEMS yeast research.

Assembly of amine oxidase and D‐amino acid oxidase in the cytosol of peroxisome‐deficient mutants of the yeast Hansenula polymorpha during growth of cells on glucose in the presence of primary amines or D‐alanine as the sole nitrogen source

I. J. van der Klei, M. Veenhuis, G. Sulter, 1990 .

Heterologous expression of alcohol oxidase in Saccharomyces cerevisiae: properties of the enzyme and implications for microbody development.

I. J. van der Klei, M. Veenhuis, W. Harder, 1989, FEMS microbiology letters.

Peroxisomal catalase deficiency modulates yeast lifespan depending on growth conditions

I. J. van der Klei, M. Veenhuis, S. Lefevre, 2013, Aging.

The significance of peroxisomes in methanol metabolism in methylotrophic yeast.

I. J. van der Klei, M. Veenhuis, Y. Sakai, 2006, Biochimica et biophysica acta.

Comparative Genomics of Peroxisome Biogenesis Proteins: Making Sense of the PEX Proteins

D. Devos, I. J. van der Klei, Carlos Santana-Molina, 2021, Frontiers in Cell and Developmental Biology.

Comparative genomics of peroxisome biogenesis proteins: making sense of the PEX mess

D. Devos, I. J. van der Klei, Carlos Molina, 2020, bioRxiv.

PTS1-independent sorting of peroxisomal matrix proteins by Pex5p.

I. J. van der Klei, M. Veenhuis, 2006, Biochimica et biophysica acta.

Pex14 is the sole component of the peroxisomal translocon that is required for pexophagy

I. J. van der Klei, M. Veenhuis, T. van Zutphen, 2008, Autophagy.

The significance of peroxisome function in chronological aging of Saccharomyces cerevisiae

I. J. van der Klei, R. Wanders, M. Veenhuis, 2013, Aging cell.

Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha

Arjen M. Krikken, I. J. van der Klei, Chris Williams, 2015, Scientific Reports.

Peroxisome retention involves Inp1-dependent peroxisome–plasma membrane contact sites in yeast

Arjen M. Krikken, D. Devos, I. J. van der Klei, 2020, The Journal of cell biology.

Extension of Yeast Chronological Lifespan by Methylamine

I. J. van der Klei, M. Veenhuis, S. Lefevre, 2012, PloS one.

Peroxisome Maintenance Depends on De Novo Peroxisome Formation in Yeast Mutants Defective in Peroxisome Fission and Inheritance

I. J. van der Klei, J. Wróblewska, 2019, International journal of molecular sciences.

Peroxisomes: surprisingly versatile organelles.

I. J. van der Klei, M. Veenhuis, 2002, Biochimica et biophysica acta.

Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, J. Kiel, 2008, BMC biotechnology.

Synthesis of Penicillium chrysogenum acetyl-CoA:isopenicillin N acyltransferase in Hansenula polymorpha: first step towards the introduction of a new metabolic pathway.

I. J. van der Klei, M. Veenhuis, R. Bovenberg, 2005, FEMS yeast research.

Penicillium chrysogenum Pex5p mediates differential sorting of PTS1 proteins to microbodies of the methylotrophic yeast Hansenula polymorpha.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2004, Fungal genetics and biology : FG & B.

Pyruvate carboxylase is an essential protein in the assembly of yeast peroxisomal oligomeric alcohol oxidase.

I. J. van der Klei, M. Veenhuis, Paulina Z Ozimek, 2003, Molecular biology of the cell.

Peroxisomal Remnant Structures in Hansenula polymorpha pex5 Cells Can Develop into Normal Peroxisomes upon Induction of the PTS2 Protein Amine Oxidase*

I. J. van der Klei, M. Veenhuis, F. Salomons, 2001, The Journal of Biological Chemistry.

Hansenula polymorpha: an attractive model organism for molecular studies of peroxisome biogenesis and function.

I. J. van der Klei, V. Titorenko, M. Veenhuis, 1992, FEMS microbiology letters.

At neutral pH the chronological lifespan of Hansenula polymorpha increases upon enhancing the carbon source concentrations

I. J. van der Klei, Adam Kawałek, 2014, Microbial cell.

A conserved alpha helical domain at the N‐terminus of Pex14p is required for PTS1 and PTS2 protein import in Hansenula polymorpha

I. J. van der Klei, M. Veenhuis, J. Kiel, 2007, FEBS letters.

Hansenula polymorpha and Saccharomyces cerevisiae Pex5p's recognize different, independent peroxisomal targeting signals in alcohol oxidase

Marten Veenhuis, P. Kötter, I. J. van der Klei, 2006, FEBS letters.

Restoration of peroxisome formation in two conditional peroxisome‐deficient mutants of Hansenula polymorpha during growth of cells on specific organic nitrogen sources

I. J. van der Klei, V. Titorenko, M. Veenhuis, 1995, Yeast.

Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide.

M. Wilmanns, I. J. van der Klei, M. Veenhuis, 2007, Archives of biochemistry and biophysics.

Identification and characterization of cytosolic Hansenula polymorpha proteins belonging to the Hsp70 protein family

I. J. van der Klei, J. van Beeumen, V. Titorenko, 1996, Yeast.

Use of electron microscopy in the examination of lattice defects in crystals of alcohol oxidase

W. Hol, C. Lawson, B. Dijkstra, 1989, FEBS letters.

The Hansenula polymorpha peroxisomal targeting signal 1 receptor, Pex5p, functions as a tetramer

I. J. van der Klei, E. Boekema, Dongyuan Wang, 2007, FEBS letters.

Deflavination of flavo-oxidases by nucleophilic reagents.

I. J. van der Klei, M. Veenhuis, R. Boteva, 2001, Biochimica et biophysica acta.

Engineering and Analysis of a Saccharomyces cerevisiae Strain That Uses Formaldehyde as an Auxiliary Substrate

J. Pronk, J. Daran, I. J. van der Klei, 2008, Applied and Environmental Microbiology.

Fluorescence analysis of the Hansenula polymorpha peroxisomal targeting signal-1 receptor, Pex5p.

E. Krieger, I. J. van der Klei, A. Visser, 2003, European journal of biochemistry.

Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division

I. J. van der Klei, Sanjeev Kumar, Rinse de Boer, 2018, Journal of Cell Science.

The Saccharomyces cerevisiae ICL2 Gene Encodes a Mitochondrial 2-Methylisocitrate Lyase Involved in Propionyl-Coenzyme A Metabolism

J. Pronk, P. Kötter, M. Luttik, 2000, Journal of bacteriology.

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane

Bettina Warscheid, Thomas Becker, Silke Oeljeklaus, 2012, Molecular biology of the cell.

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.

J. Martinou, I. J. van der Klei, N. Pfanner, 2011, Developmental cell.

Lipid droplet autophagy in the yeast Saccharomyces cerevisiae

S. Kohlwein, I. J. van der Klei, Harald F. Hofbauer, 2014, Molecular biology of the cell.

Hansenula polymorpha Pex1p and Pex6p are peroxisome‐associated AAA proteins that functionally and physically interact

I. J. van der Klei, M. Veenhuis, J. Kiel, 1999, Yeast.

Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth

C. Kraft, I. J. van der Klei, N. Pfanner, 2022, Cell reports.

Metabolic engineering of β-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis.

Arjen M. Krikken, J. Pronk, M. Luttik, 2012, Metabolic engineering.

Novel targeting assay uncovers targeting information within peroxisomal ABC transporter Pxa1.

Arjen M. Krikken, M. Schuldiner, E. Zalckvar, 2023, Biochimica et biophysica acta. Molecular cell research.

Cytochemical staining methods for localization of key enzymes of methanol metabolism in Hansenula polymorpha.

I. J. van der Klei, M. Veenhuis, 1990, Methods in enzymology.

Electron tomography of mitochondria after the arrest of protein import associated with Tom19 depletion.

G A Perkins, T G Frey, M H Ellisman, 2001, European journal of cell biology.

Gluing yeast peroxisomes - composition and function of membrane contact sites.

I. J. van der Klei, Rinse de Boer, Fei Wu, 2023, Journal of cell science.

Peroxisomes: new insights into protein sorting, dynamics, quality control, signalling and roles in health and disease

E. Zalckvar, I. J. van der Klei, P. Kim, 2019, Histochemistry and Cell Biology.

Moonlighting proteins: an intriguing mode of multitasking.

Daphne H. E. W. Huberts, I. J. van der Klei, Daphne Huberts, 2010, Biochimica et biophysica acta.

Pexophagy: autophagic degradation of peroxisomes.

I. J. van der Klei, J. Kiel, Y. Sakai, 2006, Biochimica et biophysica acta.

Pexophagy: autophagic degradation of peroxisomes.

I. J. van der Klei, J. Kiel, Y. Sakai, 2006, Biochimica et biophysica acta.

Hansenula polymorpha Pex3p Is a Peripheral Component of the Peroxisomal Membrane*

Arjen M. Krikken, K. Faber, I. J. van der Klei, 2002, Journal of Biological Chemistry.

Overproduction of Pex5p Stimulates Import of Alcohol Oxidase and Dihydroxyacetone Synthase in a Hansenula polymorpha pex14Null Mutant*

K. Faber, I. J. van der Klei, M. Veenhuis, 2000, The Journal of Biological Chemistry.

The significance of peroxisomes in methanol metabolism in methylotrophic yeast.

I. J. van der Klei, M. Veenhuis, Y. Sakai, 2006, Biochimica et biophysica acta.

Absence of the peroxiredoxin Pmp20 causes peroxisomal protein leakage and necrotic cell death.

H. Jungwirth, S. Kohlwein, I. J. van der Klei, 2008, Free radical biology & medicine.

Engineering and Analysis of a Saccharomyces cerevisiae Strain That Uses Formaldehyde as an Auxiliary Substrate

J. Pronk, J. Daran, I. J. van der Klei, 2008, Applied and Environmental Microbiology.

The Significance of Peroxisomes in Methanol Metabolism in Methylotrophic Yeast Article in Press

I. J. van der Klei, Y. Sakai, H. Yurimoto, 2022 .

Import of assembled PTS1 proteins into peroxisomes of the yeast Hansenula polymorpha: yes and no!

K. Faber, I. J. van der Klei, M. Veenhuis, 2002, Biochimica et biophysica acta.

Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha

Arjen M. Krikken, I. J. van der Klei, Chris Williams, 2015, Scientific Reports.

Reassembly of peroxisomes in Hansenula polymorpha pex3 cells on reintroduction of Pex3p involves the nuclear envelope.

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2006, FEMS yeast research.

Peroxisome reintroduction in Hansenula polymorpha requires Pex25 and Rho1

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2015, The Journal of cell biology.

Peroxisome reintroduction in Hansenula polymorpha requires Pex25 and Rho1

Arjen M. Krikken, I. J. van der Klei, M. Veenhuis, 2011, The Journal of cell biology.

Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene.

I. J. van der Klei, M. Veenhuis, J. Kiel, 2007, FEMS yeast research.

An Engineered Yeast Efficiently Secreting Penicillin

W. V. van Gulik, I. J. van der Klei, M. Veenhuis, 2009, PloS one.

Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.

J. Martinou, I. J. van der Klei, N. Pfanner, 2011, Developmental cell.

Quantitative Analysis of Organelle Abundance, Morphology and Dynamics Quantitative Analysis of Organelle Abundance, Morphology and Dynamics This Review Comes from a Themed Issue on Analytical Biotechnology Edited

I. J. van der Klei, I. V. D. Klei, T. Zutphen, 2022 .