C. Woolf

发表

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.

Robert H. Brown, K. Eggan, G. Boulting, 2014, Cell reports.

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

Kenneth S. Kosik, Giovanni Coppola, Zhigang He, 2015, Neuron.

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

Andreas Hess, Josef M. Penninger, Mark Rosenzweig, 2010, Cell.

The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord

J E Swett, J. Swett, C. Woolf, 1985, The Journal of comparative neurology.

Analgesic drug development: time to break the mould

C. Woolf, 2013, The Journal of Headache and Pain.

Central sensitization: Implications for the diagnosis and treatment of pain

C. Woolf, 2011, PAIN.

Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity.

G. A. Wilkinson, J. Holstege, C. Woolf, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity

D. Zaykin, J. Jordan, W. Maixner, 2012, Nature Medicine.

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

Wardiya Afshar Saber, K. Kapur, K. Eggan, 2014, Nature Neuroscience.

Persistent postsurgical pain: risk factors and prevention

H. Kehlet, C. Woolf, T. Jensen, 2006, The Lancet.

Contribution of interleukin‐1β to the inflammation‐induced increase in nerve growth factor levels and inflammatory hyperalgesia

C. Woolf, S. Poole, B. Safieh-Garabedian, 1995, British journal of pharmacology.

Evidence for a central component of post-injury pain hypersensitivity

C. Woolf, 1983, Nature.

Neuronal plasticity: increasing the gain in pain.

C. Woolf, M. Salter, 2000, Science.

Central sensitization: a generator of pain hypersensitivity by central neural plasticity.

C. Woolf, Alban Latremoliere, 2009, The journal of pain : official journal of the American Pain Society.

TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction

Clifford J. Woolf, David P. Corey, D. Corey, 2006, Neuron.

A three-dimensional human neural cell culture model of Alzheimer’s disease

Basavaraj Hooli, Can Zhang, Michael Peitz, 2014, Nature.

Recovery of C-Fiber-Induced Extravasation Following Peripheral Nerve Injury in the Rat

C. Woolf, A. Allchorne, H. Bester, 1998, Experimental Neurology.

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

C. Woolf, I. Decosterd, Clifford J Woolf, 2000, Pain.

Central sensitization and LTP: do pain and memory share similar mechanisms?

C. Woolf, R. Ji, K. Moore, 2003, Trends in Neurosciences.

Composite Pain Biomarker Signatures for Objective Assessment and Effective Treatment

Clifford J. Woolf, Irene Tracey, I. Tracey, 2019, Neuron.

Nociceptors—Noxious Stimulus Detectors

Clifford J. Woolf, C. Woolf, Q. Ma, 2007, Neuron.

Mechanism-based Pain Diagnosis: Issues for Analgesic Drug Development

M. Max, C. Woolf, C J Woolf, 2001, Anesthesiology.

Time dependence of a neurochemical correlate of a learning task: A non-disruptive approach to memory consolidation

C. Woolf, H. Hepburn, C. Rosendorff, 1974, Experientia.

Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration

Christine M. Miller, B. Barres, Michio W. Painter, 2014, Neuron.

Neuropathic pain: aetiology, symptoms, mechanisms, and management

C. Woolf, R. Mannion, Clifford J Woolf, 1999, The Lancet.

ALS IMPLICATED PROTEIN TDP-43 SUSTAINS LEVELS OF STMN2 A MEDIATOR OF MOTOR NEURON GROWTH AND REPAIR

Michael J. Steinbaugh, K. Eggan, Luis A. Williams, 2019, Nature Neuroscience.

Optical cuff for optogenetic control of the peripheral nervous system

G. Courtine, S. Lacour, L. Asboth, 2018, Journal of neural engineering.

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

K. Channon, Michio W. Painter, N. Ferreirós, 2015, Neuron.

Morphine-sensitive and morphine-insensitive actions of C-fibre input on the rat spinal cord

P. Wall, C. Woolf, 1986, Neuroscience Letters.

CD11b+Ly6G− myeloid cells mediate mechanical inflammatory pain hypersensitivity

J. Julien, C. Woolf, I. Chiu, 2015, Proceedings of the National Academy of Sciences.

Inhibition of Fever

C. Woolf, C. Rosendorff, 1979 .

Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration

D. Geschwind, Y. Ao, M. Sofroniew, 2020 .

Toward a Mechanism-Based Approach to Pain Diagnosis.

C. Woolf, R. Mannion, Daniel Vardeh, 2016, The journal of pain : official journal of the American Pain Society.

Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

D. Geschwind, C. Woolf, R. Kawaguchi, 2020, Neuron.

Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

D. Geschwind, C. Woolf, R. Kawaguchi, 2019, Neuron.

miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds

Allon M. Klein, M. Kirschner, V. Li, 2017, bioRxiv.

Generation of acute pain: central mechanisms.

C. Woolf, C. Woolf, 1991, British medical bulletin.

Progressive tactile hypersensitivity after a peripheral nerve crush: non-noxious mechanical stimulus-induced neuropathic pain

C. Woolf, I. Decosterd, A. Allchorne, 2002, Pain.

Sense and Immunity: Context-Dependent Neuro-Immune Interplay

Simmie L. Foster, C. Woolf, S. Foster, 2017, Front. Immunol..

Sensory receptor mechanisms edited by W. Hamann and A. Iggo, World scientific, Singapore, 1984, 319 pp., £52.90

C. Woolf, 1985, Pain.

Dynamic changes in glypican‐1 expression in dorsal root ganglion neurons after peripheral and central axonal injury

C. Woolf, S. Bloechlinger, L. Karchewski, 2004, The European journal of neuroscience.

Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges.

David Borsook, Sean Mackey, Jianren Mao, 2013, The journal of pain : official journal of the American Pain Society.

The time course and specificity of the changes in the behavioural and dorsal horn cell responses to noxious stimuli following peripheral nerve capsaicin treatment in the rat

C. Woolf, M. Fitzgerald, 1982, Neuroscience.

Toward aMechanism-BasedApproach to Pain Diagnosis

C. Woolf, R. Mannion, Daniel Vardeh, 2016 .

Deafferentation is insufficient to induce sprouting of A‐fibre central terminals in the rat dorsal horn

T. Doubell, C. Woolf, R. Mannion, 1998, The Journal of comparative neurology.

Pain Mechanisms and Management: A Central Perspective

C. Woolf, R. Mannion, 2000, The Clinical journal of pain.

Brain Responses to Noxious Stimuli in Patients With Chronic Pain

A. Basbaum, S. Eickhoff, R. Dworkin, 2021, JAMA network open.

Role of the peripheral benzodiazepine receptor in sensory neuron regeneration

C. Woolf, Charles D. Mills, Jaquelyn L. Bitler, 2005, Molecular and Cellular Neuroscience.

Hsp27 Upregulation and Phosphorylation Is Required for Injured Sensory and Motor Neuron Survival

C. Woolf, I. Decosterd, R. Mannion, 2002, Neuron.

The brief and the prolonged facilitatory effects of unmyelinated afferent input on the rat spinal cord are independently influenced by peripheral nerve section

P. Wall, C. Woolf, 1986, Neuroscience.

Differential Analgesic Sensitivity of Two Distinct Neuropathic Pain Models

C. Woolf, I. Decosterd, A. Allchorne, 2004, Anesthesia and analgesia.

Reciprocal Schwann cell-axon interactions

C. Woolf, M. Reynolds, 1993, Current Opinion in Neurobiology.

Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity

B. Spiegelman, C. Woolf, Xing Zeng, 2017, Cell.

Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis.

C. Woolf, Herbert Y. Lin, A. Mukherjee, 2005, Endocrinology.

Epineural optogenetic activation of nociceptors initiates and amplifies inflammation

S. Lacour, Qiuting Huang, Philipp Schönle, 2020, Nature biotechnology.

Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation

Seungkyu Lee, B. Bean, C. Woolf, 2019, eLife.

Explorer Delayed sympathetic dependence in the spared nerve injury ( SNI ) model of neuropathic pain

C. Woolf, I. Decosterd, A. Allchorne, 2016 .

TRPA1 Contributes to Cold Hypersensitivity

A. Patapoutian, Matt J. Petrus, Taryn J. Earley, 2010, The Journal of Neuroscience.

COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice.

C. Saper, G. FitzGerald, C. Woolf, 2009, The Journal of clinical investigation.

Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain

C. Woolf, I. Decosterd, A. Allchorne, 2007, Molecular pain.

Peripheral axonal injury results in reduced μ opioid receptor pre- and post-synaptic action in the spinal cord

C. Woolf, K. Befort, Nobuko Ito, 2005, Pain.

Selective up‐regulation of the growth arrest DNA damage‐inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury

C. Woolf, K. Befort, L. Karchewski, 2003, The European journal of neuroscience.

The growth-associated protein gap-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury

L. Benowitz, C. Woolf, C. Molander, 1990, Neuroscience.

Diltiazem Promotes Regenerative Axon Growth

K. Kapur, S. Strittmatter, Xingxing Wang, 2018, Molecular Neurobiology.

Title Axonal G 3 BP 1 stress granule protein limits axonal mRNA translation and nerve regeneration

Edsel A. Peña, A. Burlingame, A. English, 2018 .

Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration

Edsel A. Peña, A. Burlingame, A. English, 2018, Nature Communications.

Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology

C. Woolf, I. Chiu, C. V. Hehn, 2012, Nature Neuroscience.

Time-dependent differences in the increase in GAP-43 expression in dorsal root ganglion cells after peripheral axotomy

C. Woolf, M. Reynolds, T. Sommervaille, 1991, Neuroscience.

Time for nonaddictive relief of pain

T. Grosser, G. FitzGerald, C. Woolf, 2017, Science.

Intrathecal high dose morphine produces hyperalgesia in the rat

C. Woolf, 1981, Brain Research.

Capturing Novel Non-opioid Pain Targets

C. Woolf, 2020, Biological Psychiatry.

Preemptive analgesia--treating postoperative pain by preventing the establishment of central sensitization.

C. Woolf, M. Chong, 1993 .

Bupivacaine‐induced cellular entry of QX‐314 and its contribution to differential nerve block

B. Bean, N. Ferreirós, B. Wainger, 2014, British journal of pharmacology.

Pain amplification—A perspective on the how, why, when, and where of central sensitization

C. Woolf, 2018 .

Pain: morphine, metabolites, mambas, and mutations

C. Woolf, 2013, The Lancet Neurology.

Nociceptor neurons impair cancer immunosurveillance

Simmie L. Foster, L. Ji, C. Woolf, 2021 .

Overexpression of human HSP27 protects sensory neurons from diabetes

L. Korngut, C. Woolf, D. Zochodne, 2012, Neurobiology of Disease.

Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

David P. Roberson, B. Bean, C. Woolf, 2009, Anesthesiology.

Intellectual disability-associated SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF chromatin remodeling

Clayton K. Collings, H. Seo, C. Woolf, 2020 .

Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

Clayton K. Collings, H. Seo, C. Woolf, 2019, Cell.

Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation

C. Woolf, O. Isacson, P. Hallett, 2018, Stem cell reports.

Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS

Thomas J. Crisman, D. Geschwind, K. Kapur, 2016, Neuron.

Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat

C. Woolf, Z. Wiesenfeld‐Hallin, 1986, Neuroscience Letters.

Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

David P. Roberson, C. Woolf, M. Otto, 2018, Nature Communications.

Prostanoids and pain: unraveling mechanisms and revealing therapeutic targets.

C. Woolf, A. Sapirstein, T. Samad, 2002, Trends in molecular medicine.

Vagal sensory neurons drive mucous cell metaplasia.

Simmie L. Foster, David P. Roberson, B. Bean, 2020, The Journal of allergy and clinical immunology.

BACE1 regulates voltage-gated sodium channels and neuronal activity

V. Lee, B. Carey, Doo Yeon Kim, 2007, Nature Cell Biology.

Terminal Schwann cells elaborate extensive processes following denervation of the motor endplate

C. Woolf, M. Reynolds, Clifford J. Woolf, 1992, Journal of neurocytology.

Sensory neurons display cell-type-specific vulnerability to loss of neuron-glia interactions

C. Woolf, R. Kawaguchi, M. Traka, 2022, Cell reports.

Substance P activates Mas‐related G protein–coupled receptors to induce itch

C. Woolf, S. Talbot, E. Lerner, 2017, The Journal of allergy and clinical immunology.

Inhibiting cough by silencing large pore-expressing airway sensory neurons with a charged sodium channel blocker

David P. Roberson, B. Bean, B. Levy, 2020, bioRxiv.

Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker

David P. Roberson, B. Bean, B. Levy, 2021, British journal of pharmacology.

The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans.

A. Hobson, D. Thompson, Q. Aziz, 2003, Gastroenterology.

Leukemia Inhibitory Factor Is an Anti-Inflammatory and Analgesic Cytokine

C. Woolf, P. Patterson, S. Poole, 1998, The Journal of Neuroscience.

Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation

K. Eggan, Seungkyu Lee, Ole Wiskow, 2020, Cell reports.

Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1

T. Hornemann, A. von Eckardstein, Anke Penno, 2009, The Journal of Neuroscience.

Hemojuvelin Acts as a Bone Morphogenetic Protein Co-Receptor To Regulate Hepcidin Expression.

N. Andrews, R. Chung, C. Woolf, 2005 .

Neurogenic Inflammation – The Peripheral Nervous System ’ s Role in Host Defense and Immunopathology

C. Woolf, I. Chiu, C. V. Hehn, 2012 .

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

Raymond T Chung, Yin Xia, N. Andrews, 2006, Nature Genetics.

Induction of the Oct-2 transcription factor in primary sensory neurons during inflammation is nerve growth factor-dependent

D. Latchman, C. Woolf, E. Ensor, 1996, Neuroscience Letters.

Reply to Fernando Cervero

C. Woolf, 1995, Pain.

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations

M. Rowbotham, R. Freeman, K. Patel, 2022, The journal of pain.

Pain and infection: pathogen detection by nociceptors.

C. Woolf, I. Chiu, F. A. Pinho-Ribeiro, 2016, Pain.

Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons

David P. Roberson, B. Bean, C. Woolf, 2013, Nature Neuroscience.

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

Román A. Corfas, Alan R. Mardinly, Alan R Mardinly, 2010, Neuron.

Neuroimmunity: Physiology and Pathology.

Simmie L. Foster, C. Woolf, S. Foster, 2016, Annual review of immunology.

Constitutive cyclo‐oxygenase‐2 does not contribute to the development of human visceral pain hypersensitivity

A. Hobson, D. Thompson, Q. Aziz, 2006, European journal of pain.

Identification of somatostatin sst2(a) receptor expressing neurones in central regions involved in nociception

P. Emson, C. Woolf, G. Hathway, 1998, Brain Research.

Turbocharging neurons for growth: accelerating regeneration in the adult CNS

C. Woolf, 2001, Nature Neuroscience.

Direct Activation of Rat Spinal Dorsal Horn Neurons by Prostaglandin E2

C. Woolf, K. Moore, T. Kohno, 2001, The Journal of Neuroscience.

Partial denervation of the medial gastrocnemius muscle results in growth-associated protein-43 immunoreactivity in sprouting axons and schwann cells

C. Woolf, A. Mehta, M. Reynolds, 1993, Neuroscience.

Growth‐associated protein 43 immunoreactivity in the superficial dorsal horn of the rat spinal cord is localized in atrophic C‐fiber, and not in sprouted A‐fiber, central terminals after peripheral nerve injury

T. Doubell, C. Woolf, C. Woolf, 1997, The Journal of comparative neurology.

Nociceptor neurons affect cancer immunosurveillance

Simmie L. Foster, Alexandro E. Trevino, R. Drapkin, 2022, Nature.

Preoperative morphine pre-empts postoperative pain

C. Woolf, L. Bromley, C. Richmond, 1993, The Lancet.

Understanding chronic inflammatory and neuropathic pain

S. McMahon, K. Wiech, J. Farrar, 2012, Annals of the New York Academy of Sciences.

Gabapentin — Actions on adult superficial dorsal horn neurons

C. Woolf, H. Baba, K. Moore, 2002, Neuropharmacology.

Supplemental Information Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb 5 mutant mice

Román A. Corfas, Alan R. Mardinly, Alan R Mardinly, 2010 .

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program

Giovanni Coppola, Zhigang He, Peter Langfelder, 2016, Neuron.

Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer

L. Rubin, K. Channon, J. Penninger, 2022, Science Translational Medicine.

Neuropathic pain: aetiology, s y m p t o m s , m e c h a n i s m s , a n d m a n a g e m e n t

C. Woolf, R. Mannion, 1999 .

Automated preclinical detection of mechanical pain hypersensitivity and analgesia

Alexander B. Wiltschko, David P. Roberson, James P. Bohnslav, 2022, Pain.

Pain modulation in the spinal cord

C. Woolf, 2022, Frontiers in Pain Research.

Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain.

D. Clapham, C. Woolf, K. Kahle, 2014, JAMA neurology.

Future directions in neuropathic pain therapy: closing the translational loop.

C. Woolf, M. Backonja, 2010, The oncologist.

The site of action of corticosteroid antipyresis in the rabbit.

C. Woolf, G. Willies, 1980, The Journal of physiology.

The effect of sodium salicylate on dibutyryl cyclic amp fever in the conscious rabbit

C. Woolf, C. Rosendorff, G. Willies, 1976, Neuropharmacology.

Pyrogen and prostaglandin fever in the rabbit—II: Effects of noradrenaline depletion and adrenergic receptor blockade

C. Woolf, C. Rosendorff, G. Willies, 1975, Neuropharmacology.

The effect of intracerebroventricular injections of morphine on vasopressin release in the rat.

C. Woolf, M. Forsling, L. Aziz, 1981, The Journal of physiology.

Intracerebral naloxone and the reaction to thermal noxious stimulation in the rat

C. Woolf, 1980, Brain Research.

High basal expression and injury-induced down regulation of two regulator of G-protein signaling transcripts, RGS3 and RGS4 in primary sensory neurons

C. Woolf, M. Costigan, S. Tate, 2003, Molecular and Cellular Neuroscience.

Cryoneurolysis with Injectable Ice Slurry Modulates Mechanical skin pain.

R. Anderson, A. Khodorova, C. Woolf, 2022, The Journal of investigative dermatology.

CNS injury: IL-33 sounds the alarm.

Simmie L. Foster, C. Woolf, S. Foster, 2015, Immunity.

Diltiazem Promotes Regenerative Axon Growth

K. Kapur, S. Strittmatter, Xingxing Wang, 2018, Molecular Neurobiology.

The induction and maintenance of central sensitization is dependent on N-methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

Clifford J. Woolf, C. Woolf, S. Thompson, 1991, Pain.

Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input

Patrick D. Wall, Clifford J. Woolf, Stephen B. McMahon, 1987, Nature.

Recent advances in the pathophysiology of acute pain.

C. Woolf, Clifford J. Woolf, 1989, British journal of anaesthesia.

Analgesia and hyperalgesia produced in the rat by intrathecal naloxone

C. Woolf, 1980, Brain Research.

Somatic pain--pathogenesis and prevention.

C. Woolf, C. Woolf, 1995, British journal of anaesthesia.

Towards a mechanism-based classification of pain?

R. Lipton, R. Dubner, G. Bennett, 1998, Pain.

The systemic administration of local anaesthetics produces a selective depression of C-afferent fibre evoked activity in the spinal cord

C. Woolf, Z. Wiesenfeld‐Hallin, 1985, Pain.

The stereospecific effect of naloxone on rat dorsal horn neurones; Inhibition in superficial laminae and excitation in deeper laminae

C. Woolf, M. Fitzgerald, 1980, PAIN.

Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy.

C. Woolf, 2004, Life sciences.

Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

Jianzhu Chen, Honghua Yang, D. Chen, 2018, Nature Communications.

Can we conquer pain?

C. Woolf, J. Scholz, 2002, Nature Neuroscience.

A functionally characterized test set of human induced pluripotent stem cells

Hynek Wichterle, Kevin Eggan, Derek H. Oakley, 2011, Nature Biotechnology.

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

Jörn Lötsch, David Goldman, Gerd Geisslinger, 2006, Nature Medicine.

Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.

Minna Männikkö, David Goldman, Jaro Karppinen, 2010, Brain : a journal of neurology.

Neuropathic pain: a maladaptive response of the nervous system to damage.

Michael Costigan, C. Woolf, M. Costigan, 2009, Annual review of neuroscience.

Ionotropic and Metabotropic Receptors, Protein Kinase A, Protein Kinase C, and Src Contribute to C-Fiber-Induced ERK Activation and cAMP Response Element-Binding Protein Phosphorylation in Dorsal Horn Neurons, Leading to Central Sensitization

C. Woolf, K. Befort, R. Ji, 2004, The Journal of Neuroscience.

ERK MAP Kinase Activation in Superficial Spinal Cord Neurons Induces Prodynorphin and NK-1 Upregulation and Contributes to Persistent Inflammatory Pain Hypersensitivity

C. Woolf, K. Befort, R. Ji, 2002, The Journal of Neuroscience.

Ro5‐4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats

C. Woolf, M. Costigan, G. Raivich, 2008, The European journal of neuroscience.

A Role for HSP27 in Sensory Neuron Survival

R. Coggeshall, C. Woolf, M. Costigan, 1999, The Journal of Neuroscience.

Complement Induction in Spinal Cord Microglia Results in Anaphylatoxin C5a-Mediated Pain Hypersensitivity

Clifford J. Woolf, Michael Costigan, Andrew Moss, 2007, The Journal of Neuroscience.

p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia

C. Woolf, R. Ji, Shan-xue Jin, 2002, Neuron.

Breaking barriers to novel analgesic drug development

David P. Roberson, B. Bean, C. Woolf, 2017, Nature Reviews Drug Discovery.

Neuronal Plasticity and Signal Transduction in Nociceptive Neurons: Implications for the Initiation and Maintenance of Pathological Pain

Clifford J. Woolf, C. Woolf, R. Ji, 2001, Neurobiology of Disease.

The NMDA receptor, pain and central sensitization

C. Woolf, Q. Ma, Qing-Ping Ma, 2002 .

Prostaglandin E2 Receptor EP4 Contributes to Inflammatory Pain Hypersensitivity

C. Woolf, L. Barrett, F. Amaya, 2006, Journal of Pharmacology and Experimental Therapeutics.

Analgesia by inhibiting tetrahydrobiopterin synthesis.

C. Woolf, Alban Latremoliere, M. Costigan, 2012, Current opinion in pharmacology.

Inflammation-induced decrease in voluntary wheel running in mice: A nonreflexive test for evaluating inflammatory pain and analgesia

C. Woolf, E. J. Cobos, Kelly Duong, 2012, PAIN®.

The effect of an inhibitor of adenylate cyclase on the development of pyrogen, prostaglandin and cyclic AMP fevers in the rabbit

C. Woolf, C. Rosendorff, G. Willies, 1976, Pflügers Archiv.

Pyrogen and prostaglandin fever in the rabbit—I: Effects of salicylate and the role of cyclic AMP

C. Woolf, C. Rosendorff, G. Willies, 1975, Neuropharmacology.

From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial.

Kevin Eggan, K. Eggan, B. Wainger, 2015, Cell stem cell.

Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

Adam Sapirstein, Clifford J. Woolf, Joseph V. Bonventre, 2001, Nature.

Skin β-Endorphin Mediates Addiction to UV Light

K. C. Robinson, C. Woolf, J. Mao, 2014, Cell.

Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations

J. Farrar, H. Kehlet, M. Ashburn, 2021, Pain reports.

Research design considerations for chronic pain prevention clinical trials: IMMPACT recommendations

J. Farrar, H. Kehlet, M. Ashburn, 2015, Pain.

A Novel Tool for the Assessment of Pain: Validation in Low Back Pain

Bhupendra Rawal, Clifford J. Woolf, Salahadin Abdi, 2009, PLoS medicine.

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

Clifford J. Woolf, Bruce P. Bean, B. Bean, 2007, Nature.

Common patterns of plasticity contributing to nociceptive sensitization in mammals and Aplysia

E. Walters, C. Woolf, 1991, Trends in Neurosciences.

The Paired Homeodomain Protein DRG11 Is Required for the Projection of Cutaneous Sensory Afferent Fibers to the Dorsal Spinal Cord

David J. Anderson, A. Basbaum, A. Malmberg, 2001, Neuron.

Decreased alertness due to sleep loss increases pain sensitivity in mice

T. Scammell, C. Alexandre, C. Woolf, 2017, Nature Medicine.

Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat

P. Wall, C. Woolf, 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Injury-induced plasticity of the flexor reflex in chronic decerebrate rats

S. McMahon, C. Woolf, 1985, Neuroscience.

Muscle but not cutaneous C‐afferent input produces prolonged increases in the excitability of the flexion reflex in the rat.

Patrick D. Wall, Clifford J. Woolf, P. Wall, 1984 .

The cutaneous contribution to the hamstring flexor reflex in the rat: an electrophysiological and anatomical study

J. Swett, C. Woolf, 1984, Brain Research.

A New Strategy for the Treatment of Inflammatory Pain

C. Woolf, 2012, Drugs.

Morphine, the NMDA receptor antagonist MK801 and the tachykinin NK1 receptor antagonist RP67580 attenuate the development of inflammation-induced progressive tactile hypersensitivity

C. Woolf, Q. Ma, A. Allchorne, 1998, Pain.

Tachykinin NK1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats.

C. Woolf, Q. Ma, Q. P. Ma, 1997, European journal of pharmacology.

Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons

T. Doubell, C. Woolf, T. Leslie, 1996, Nature.

Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord

Clifford J. Woolf, C. Woolf, Q. Ma, 1996, PAIN.

Noxious stimuli induce an N-methyl-d-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia

C. Woolf, Q. Ma, Qing-Ping Ma, 1995, Pain.

The pathophysiology of chronic pain — increased sensitivity to low threshold Aβ-fibre inputs

T. Doubell, C. Woolf, 1994, Current Opinion in Neurobiology.

Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation

Clifford J. Woolf, C. Woolf, L. Sivilotti, 1994, Pain.

Mechanisms of pain and their therapeutic implications.

C. Woolf, W. Muir, C. Woolf, 2001, Journal of the American Veterinary Medical Association.

NK1 and NK2 receptors contribute to C‐fibre evoked slow potentials in the spinal cord

C. Woolf, I. Nagy, C. Woolf, 1994, Neuroreport.

Structural Plasticity of Primary Afferent Terminals in the Adult Dorsal Horn — Regenerative Sprouting Induced by Peripheral Nerve Injury

C. Woolf, 1994 .

The pathophysiology of peripheral neuropathic pain--abnormal peripheral input and abnormal central processing.

C. Woolf, Clifford J. Woolf, 1993, Acta neurochirurgica. Supplementum.

Peripheral nerve injury triggers central sprouting of myelinated afferents

R. Coggeshall, C. Woolf, P. Shortland, 1992, Nature.

p38 Mitogen-Activated Protein Kinase Is Activated after a Spinal Nerve Ligation in Spinal Cord Microglia and Dorsal Root Ganglion Neurons and Contributes to the Generation of Neuropathic Pain

C. Woolf, R. Ji, Shan-xue Jin, 2003, The Journal of Neuroscience.

Long term alterations in the excitability of the flexion reflex produced by peripheral tissue injury in the chronic decerebrate rat

Clifford J. Woolf, C. Woolf, 1984, Pain.

Developing nociceptor-selective treatments for acute and chronic pain

B. Bean, I. Singeç, C. Woolf, 2021, Science Translational Medicine.

Contribution of central sensitisation to the development of noncardiac chest pain

A. Hobson, D. Thompson, Q. Aziz, 2000, The Lancet.

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

C. Woolf, H. Baba, R. Ji, 1999, Nature Neuroscience.

Resection of sciatic nerve re-triggers central sprouting of A-fibre primary afferents in the rat

C. Woolf, Q. Ma, Li Tian, 2000, Neuroscience Letters.

Chronic peripheral nerve section results in a rearrangement of the central axonal arborizations of axotomized A beta primary afferent neurons in the rat spinal cord

C. Woolf, P. Shortland, Peter Shortland, 1993, The Journal of comparative neurology.

Distribution of the growth associated protein GAP-43 in the central processes of axotomized primary afferents in the adult rat spinal cord; presence of growth cone-like structures

R. Coggeshall, C. Woolf, M. Reynolds, 1991, Neuroscience Letters.

Physiology and morphology of multireceptive neurons with C-afferent fiber inputs in the deep dorsal horn of the rat lumbar spinal cord.

C. Woolf, A. King, Clifford J. Woolf, 1987, Journal of neurophysiology.

Prolonged C-fibre mediated facilitation of the flexion reflex in the rat is not due to changes in afferent terminal or motoneurone excitability

P. Wall, C. Woolf, A. Cook, 1986, Neuroscience Letters.

Lignocaine selectively reduces C fibre-evoked neuronal activity in rat spinal cord in vitro by decreasing N-methyl-d-aspartate and neurokinin receptor-mediated post-synaptic depolarizations; implications for the development of novel centrally acting analgesics

C. Woolf, I. Nagy, 1996, Pain.

Null Mutations Lacking Substance: Elucidating Pain Mechanisms by Genetic Pharmacology

C. Woolf, R. Mannion, S. Neumann, 1998, Neuron.

The neuropathic pain triad: neurons, immune cells and glia

C. Woolf, J. Scholz, Clifford J Woolf, 2007, Nature Neuroscience.

Detection of cold pain, cold allodynia and cold hyperalgesia in freely behaving rats

C. Woolf, A. Allchorne, D. C. Broom, 2005, Molecular pain.

Delayed loss of small dorsal root ganglion cells after transection of the rat sciatic nerve

R. Coggeshall, C. Woolf, T. Tandrup, 2000, The Journal of comparative neurology.

ATF3 Increases the Intrinsic Growth State of DRG Neurons to Enhance Peripheral Nerve Regeneration

C. Woolf, R. Seijffers, Charles D. Mills, 2007, The Journal of Neuroscience.

Touch and Tactile Neuropathic Pain Sensitivity Are Set by Corticospinal Projections

Chinfei Chen, C. Alexandre, C. Woolf, 2018, Nature.

Changes in tactile stimuli‐induced behavior and c‐Fos expression in the superficial dorsal horn and in parabrachial nuclei after sciatic nerve crush

C. Woolf, S. Beggs, H. Bester, 2000, The Journal of comparative neurology.

Central changes in primary afferent fibers following peripheral nerve lesions

R. Coggeshall, T. Doubell, C. Woolf, 1997, Neuroscience.

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

C. Woolf, R. Ji, P. Gerner, 2005, Pain.

Proceedings of the 11th World Congress on Pain

C. Woolf, M. Bond, J. Charlton, 1991 .

Transient receptor potential channels: targeting pain at the source

A. Patapoutian, C. Woolf, S. Tate, 2009, Nature Reviews Drug Discovery.

Bradykinin Enhances AMPA and NMDA Receptor Activity in Spinal Cord Dorsal Horn Neurons by Activating Multiple Kinases to Produce Pain Hypersensitivity

C. Woolf, F. Amaya, R. Ji, 2008, The Journal of Neuroscience.

T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity

Maria Fitzgerald, Michael Costigan, Andrew Moss, 2009, The Journal of Neuroscience.

Bacteria activate sensory neurons that modulate pain and inflammation

S. Hwang, B. Wainger, C. Woolf, 2013, Nature.

Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss

R. Coggeshall, G. Corfas, C. Woolf, 2003, Nature Neuroscience.

Runx1 Determines Nociceptive Sensory Neuron Phenotype and Is Required for Thermal and Neuropathic Pain

T. Jessell, C. Woolf, J. C. D. Nooij, 2006, Neuron.

Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity

David P. Roberson, David E. Strochlic, S. Liberles, 2014, eLife.

Conversion of mouse and human fibroblasts into functional spinal motor neurons.

Kevin Eggan, K. Eggan, B. Wainger, 2011, Cell stem cell.

Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury.

K. Kosik, G. Coppola, Michio W. Painter, 2017, Cell reports.

Enhanced neuronal regeneration in the CAST/Ei mouse strain is linked to expression of differentiation markers after injury

K. Kosik, G. Coppola, Michio W. Painter, 2017, bioRxiv.

Scalable Generation of Pseudo-Unipolar Sensory Neurons from Human Pluripotent Stem Cells

Carlos A. Tristan, A. Simeonov, B. Bean, 2022, bioRxiv.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

E. McNeill, K. Channon, A. Waisman, 2018, Nature.

Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin

K. Kapur, M. Hatten, M. Sahin, 2017, Molecular Psychiatry.

A multiparametric activity profiling platform for neuron disease phenotyping and drug screening

Anne E Carpenter, Kyle W. Karhohs, K. Eggan, 2021, bioRxiv.

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

D. Geschwind, E. Chesler, G. Coppola, 2018, Cell reports.

Nociceptors Are Interleukin-1β Sensors

Alexander M Binshtok, Katharina Zimmermann, B. Bean, 2008, The Journal of Neuroscience.

The serine protease inhibitor SerpinA3N attenuates neuropathic pain by inhibiting T cell-derived leukocyte elastase

David E. Strochlic, S. Liberles, M. Devor, 2015, Nature Medicine.

Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2.

P Facer, P. Sanseau, C. G. See, 2001, Physiological genomics.

Semaphorin 3A growth cone collapse requires a sequence homologous to tarantula hanatoxin.

C. Woolf, M. Badminton, K. Mizuno, 1999, Proceedings of the National Academy of Sciences of the United States of America.

DRAGON, a Bone Morphogenetic Protein Co-receptor*

A. Brivanlou, C. Woolf, L. Attisano, 2005, Journal of Biological Chemistry.

Developmental Expression of the TTX-Resistant Voltage-Gated Sodium Channels Nav1.8 (SNS) and Nav1.9 (SNS2) in Primary Sensory Neurons

C. Woolf, M. Costigan, M. Fitzgerald, 2001, The Journal of Neuroscience.

Transcription factor network analysis identifies REST/NRSF as an intrinsic regulator of CNS regeneration

D. Geschwind, Y. Ao, M. Sofroniew, 2020, bioRxiv.

Central sensitization: uncovering the relation between pain and plasticity.

C. Woolf, Clifford J. Woolf, 2007, Anesthesiology.

Adult neuron survival strategies — slamming on the brakes

C. Woolf, Susanna C. Benn, 2004, Nature Reviews Neuroscience.

JPET # 105569 1 Prostaglandin E 2 receptor EP 4 contributes to inflammatory pain hypersensitivity

C. Woolf, L. Barrett, F. Amaya, 2006 .

β-Endorphin mediates radiation therapy fatigue

P. Biggs, C. Woolf, C. Fung, 2022, Science advances.

Non-surgical mouse model of endometriosis-associated pain that responds to clinically active drugs.

C. Woolf, Nick A. Andrews, M. S. Rogers, 2020, Pain.

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

J. Lötsch, C. Woolf, G. Geisslinger, 2008, European journal of pain.

Pain: Moving from Symptom Control toward Mechanism-Specific Pharmacologic Management

Clifford J. Woolf, C. Woolf, 2004, Annals of Internal Medicine.

Plasticity and pain: role of the dorsal horn

C. Woolf, M. Salter, 2006 .

The Role of Iron Regulation in Immunometabolism and Immune-Related Disease

J. Penninger, C. Woolf, S. Cronin, 2019, Front. Mol. Biosci..

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury.

Michael Costigan, C. Woolf, K. Befort, 2002, BMC Neuroscience.

Cytokine-nerve growth factor interactions in inflammatory hyperalgesia

C. Woolf, S. Poole, 1999 .

Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.

K. Gable, Robert H. Brown, J. Harmon, 2005, Human molecular genetics.

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

K. Mackie, C. Woolf, C. Michalski, 2007, Nature Neuroscience.

Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity

C. Woolf, Q. Ma, J. Winter, 1994, Neuroscience.

Antinociceptive effect of peripheral segmental electrical stimulation in the rat

C. Woolf, D. Mitchell, G. D. Barrett, 1980, Pain.

CLASSIC PAPERS REVISITED

C. Woolf, D. Warner, Clifford J. Woolf, 2007 .

The development and maintenance of human visceral pain hypersensitivity is dependent on the N-methyl-D-aspartate receptor.

A. Hobson, D. Thompson, Q. Aziz, 2004, Gastroenterology.

Central neural mechanisms mediating human visceral hypersensitivity.

Q Aziz, P L Furlong, P. Furlong, 2001, American journal of physiology. Gastrointestinal and liver physiology.

Pain : mechanisms and management

C. Woolf, J. Wells, 1991 .

What is this thing called pain?

C. Woolf, 2010, The Journal of clinical investigation.

A single preoperative oral dose of valdecoxib, a new cyclooxygenase-2 specific inhibitor, relieves post-oral surgery or bunionectomy pain.

C. Woolf, P. Desjardins, V. Shu, 2002, Anesthesiology.

Treated With Angiotensin-Converting Enzyme Inhibition Neutral Endopeptidase Inhibition Augments Vascular Actions of Bradykinin in Patients

J. Rouleau, C. Woolf, Nobuko Ito, 2011 .

Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones

C. Woolf, J. Winter, M. Hu-Tsai, 1996, Neuroscience Letters.

Nerve growth factor contributes to the up-regulation of growth-associated protein 43 and preprotachykinin a messenger RNAs in primary sensory neurons following peripheral inflammation

P. Emson, C. Woolf, P. Dowd, 1995, Neuroscience.

Peripheral Inflammation Facilitates Aβ Fiber-Mediated Synaptic Input to the Substantia Gelatinosa of the Adult Rat Spinal Cord

T. Doubell, C. Woolf, H. Baba, 1999, The Journal of Neuroscience.

Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cord

C. Woolf, M. Fitzgerald, 1986, The Journal of comparative neurology.

Central mechanisms of acute pain

C. Woolf, 1990, Pain.

Transcriptional and posttranslational plasticity and the generation of inflammatory pain.

C. Woolf, M. Costigan, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Preoperative Morphine Preempts Postoperative Pain

C. Woolf, C. Richmond, L. M. Bromely, 1994 .

Pain: molecular mechanisms.

C. Woolf, M. Costigan, Clifford J. Woolf, 2000, The journal of pain : official journal of the American Pain Society.

Mast cell-derived BH4 is a critical mediator of postoperative pain

T. Köcher, K. Channon, J. Penninger, 2023, bioRxiv.

Alterations in the structure, function, and chemistry of C fibers following local application of vinblastine to the sciatic nerve of the rat

C. Woolf, M. Fitzgerald, P. Mallaburn, 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Subthreshold components of the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat lumbar spinal cord.

C. Woolf, A. King, 1989, Journal of neurophysiology.

Capsaicin Combined with Local Anesthetics Preferentially Prolongs Sensory/Nociceptive Block in Rat Sciatic Nerve

B. Bean, N. Hevelone, C. Woolf, 2008, Anesthesiology.

The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord.

C. Woolf, L. Sivilotti, L. Sivilotti, 1994, Journal of neurophysiology.

Phenotypic modification of primary sensory neurons: the role of nerve growth factor in the production of persistent pain.

C. Woolf, Clifford J. Woolf, 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

FcεR1 expressing nociceptors trigger allergic airway inflammation.

Simmie L. Foster, B. Levy, C. Woolf, 2021, The Journal of allergy and clinical immunology.

Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice.

D. Geschwind, G. Coppola, C. Woolf, 2011, The Journal of clinical investigation.

Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner

C. Woolf, J. Winter, P. Wren, 1999, Neuroscience.

Neurotoxic damage evokes regenerative responses from adult rat sensory neurones

L. Benowitz, C. Woolf, R. Lindsay, 1992, Neuroscience Letters.

Regional differences in the distribution of capsaicin-sensitive target-identified adult rat dorsal root ganglion neurons

C. Woolf, J. Winter, M. Hu-Tsai, 1992, Neuroscience Letters.

Collateral Sprouting of Uninjured Primary Afferent A-Fibers into the Superficial Dorsal Horn of the Adult Rat Spinal Cord after Topical Capsaicin Treatment to the Sciatic Nerve

R. Coggeshall, T. Doubell, C. Woolf, 1996, The Journal of Neuroscience.

Use and abuse of opioid analgesics: potential methods to prevent and deter non-medical consumption of prescription opioids.

C. Woolf, M. Hashmi, 2004, Current opinion in investigational drugs.

Collateral sprouting of the central terminals of cutaneous primary afferent neurons in the rat spinal cord: Pattern, morphology, and influence of targets

C. Woolf, M. Fitzgerald, P. Shortland, 1990, The Journal of comparative neurology.

Unraveling the Plastic Peripheral Neuroimmune Interactome

C. Woolf, A. Jain, Sara Hakim, 2020, The Journal of Immunology.

Diversity of Expression of the Sensory Neuron-Specific TTX-Resistant Voltage-Gated Sodium Ion Channels SNS and SNS2

C. Woolf, M. Costigan, I. Decosterd, 2000, Molecular and Cellular Neuroscience.

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties

C. Woolf, A. Srinivasan, R. Ji, 2004, The Journal of Neuroscience.

Blocking Caspase Activity Prevents Transsynaptic Neuronal Apoptosis and the Loss of Inhibition in Lamina II of the Dorsal Horn after Peripheral Nerve Injury

R. Coggeshall, C. Woolf, D. Youn, 2005, The Journal of Neuroscience.

Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn

C. Woolf, H. Baba, R. Ji, 2003, Molecular and Cellular Neuroscience.

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling

S. Arber, G. Coppola, Rishard Salie, 2011, The Journal of Neuroscience.

Repulsive Guidance Molecule (RGMa), a DRAGON Homologue, Is a Bone Morphogenetic Protein Co-receptor*

C. Woolf, Herbert Y. Lin, Jodie L Babitt, 2005, Journal of Biological Chemistry.

GDNF selectively promotes regeneration of injury-primed sensory neurons in the lesioned spinal cord

C. Woolf, M. Costigan, R. Griffin, 2007, Molecular and Cellular Neuroscience.

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size

A. Burlingame, K. Medzihradszky, C. Woolf, 2016, Cell reports.

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

Morgan L. Maeder, Derek H. Oakley, Mathew J. Goodwin, 2014, Cell stem cell.

A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS.

L. Rubin, B. Wainger, C. Woolf, 2013, Cell stem cell.

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

Zehua Chen, M. Sahin, C. Woolf, 2015, The Journal of Neuroscience.

5,6-EET Is Released upon Neuronal Activity and Induces Mechanical Pain Hypersensitivity via TRPA1 on Central Afferent Terminals

C. Woolf, C. V. von Hehn, Zhen-Zhong Xu, 2012, The Journal of Neuroscience.

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation

R. Brandes, C. Woolf, I. Fleming, 2011, Molecular pain.

Upregulation of the Voltage-Gated Sodium Channel β2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory Neurons

Clifford J. Woolf, Lori L. Isom, Donat R. Spahn, 2005, The Journal of Neuroscience.

DeepEthogram: a machine learning pipeline for supervised behavior classification from raw pixels

Clifford J. Woolf, Christopher D. Harvey, James P. Bohnslav, 2020, bioRxiv.

Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

L. Arendt-Nielsen, L. F. Frey Law, M. Nevitt, 2015, Arthritis & rheumatology.

DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels

James P. Bohnslav, Nivanthika K. Wimalasena, Lauren L. Orefice, 2021, eLife.

Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons

C. Bountra, C. Woolf, M. Costigan, 1998, Nature Neuroscience.

Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation

Simmie L. Foster, David P. Roberson, Seungkyu Lee, 2015, Neuron.

Silencing Nociceptor Neur ons Reduces Allergic Airway Inflammation Highlights

Simmie L. Foster, David P. Roberson, Seungkyu Lee, 2015 .

CLP1 links tRNA metabolism to progressive motor-neuron loss

Markus Glatzel, Josef M. Penninger, Clifford J. Woolf, 2013, Nature.

Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in rats

C. Woolf, Teri A. Herbert, J. Scholz, 2008, PAIN.

Peripheral nerve injury alters excitatory synaptic transmission in lamina II of the rat dorsal horn

Hiroshi Baba, C. Woolf, H. Baba, 2003, The Journal of physiology.

Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain

C. Woolf, M. Parnham, R. Ji, 2016, Proceedings of the National Academy of Sciences.

Cyclooxygenase 2 expression in the spared nerve injury model of neuropathic pain

C. Woolf, G. Geisslinger, T. Kohno, 2004, Neuroscience.

TrpA1 Regulates Thermal Nociception in Drosophila

P. Garrity, M. Rosenzweig, A. Keene, 2011, PloS one.

Heat Shock Protein 27: Developmental Regulation and Expression after Peripheral Nerve Injury

R. Coggeshall, C. Woolf, M. Costigan, 1998, The Journal of Neuroscience.

The transcription factor ATF-3 promotes neurite outgrowth

C. Woolf, R. Seijffers, A. Allchorne, 2006, Molecular and Cellular Neuroscience.

Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons

F. Alt, L. Rubin, G. Coppola, 2021, Cell reports.

Pain TRPs

C. Woolf, Haibin Wang, 2005, Neuron.

Deconstructing the Neuropathic Pain Phenotype to Reveal Neural Mechanisms

Ralf Baron, Clifford J. Woolf, R. Baron, 2012, Neuron.

Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes

K. Tracey, M. Ochani, C. Woolf, 2015, Bioelectronic medicine.

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Benjamin M. Gyori, P. Sorger, C. Woolf, 2023, bioRxiv.

Overcoming obstacles to developing new analgesics

C. Woolf, Clifford J Woolf, 2010, Nature Medicine.

Sensitivity and sensitisation in relation to pain severity in knee osteoarthritis: trait or state?

L. Arendt-Nielsen, M. Nevitt, D. Felson, 2013, Annals of the rheumatic diseases.

Neurogenic extravasation and substance P levels are low in muscle as compared to skin in the rat hindlimb

P. Wall, S. McMahon, C. Woolf, 1984, Neuroscience Letters.

Trigeminal neuralgia: opportunities for research and treatment

J. Levine, C. Kitt, C. Woolf, 2000, Pain.

PII: S0304-3959(99)00310-3

J. Levine, C. Kitt, C. Woolf, 2000 .

Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever.

C. Woolf, C. Rosendorff, G. Willies, 1974, The Journal of physiology.

Bradykinin Produces Pain Hypersensitivity by Potentiating Spinal Cord Glutamatergic Synaptic Transmission

C. Woolf, Nobuko Ito, F. Amaya, 2005, The Journal of Neuroscience.

Cannabidiol activates neuronal Kv7 channels

Jennifer A. Smith, B. Bean, C. Woolf, 2021, bioRxiv.

Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC‐dependent site, serine‐896, in spinal cord dorsal horn neurons

C. Woolf, R. Ji, G. Brenner, 2004, The European journal of neuroscience.

Bradykinin and peripheral sensitization

C. Woolf, G. Brenner, C. Ehnert, 2006, Biological chemistry.

Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint

C. Woolf, M. Fitzgerald, R. Lindsay, 1989, Neuroscience.

Transcutaneous electrical nerve stimulation and the reaction to experimental pain in human subjects

C. Woolf, 1979, Pain.

Windup and central sensitization are not equivalent.

C. Woolf, 1996, Pain.

Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells

D. Geschwind, J. Sanes, Junjie Zhu, 2022, Neuron.

Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition

Clifford J. Woolf, Guy A. Rouleau, G. Rouleau, 2016, Science Signaling.

Lack of motor recovery after prolonged denervation of the neuromuscular junction is not due to regenerative failure

S. Sheu, C. Woolf, Alban Latremoliere, 2016, The European journal of neuroscience.

Phenotyping the Function of TRPV1-Expressing Sensory Neurons by Targeted Axonal Silencing

David P. Roberson, B. Bean, N. Ferreirós, 2013, The Journal of Neuroscience.

Demyelination induces transcriptional reprograming in proprioceptive and Aβ rapidly adapting low-threshold-mechanoreceptor neurons

C. Woolf, R. Kawaguchi, M. Traka, 2021, bioRxiv.

No DREAM, No Pain Closing the Spinal Gate

C. Woolf, M. Costigan, 2002, Cell.

Synaptic plasticity and central sensitization: author reply.

C. Woolf, Alban Latremoliere, Clifford J Woolf, 2010, The journal of pain : official journal of the American Pain Society.

Promoting Long‐Term Cultivation of Motor Neurons for 3D Neuromuscular Junction Formation of 3D In Vitro Using Central‐Nervous‐Tissue‐Derived Bioink

W. Chung, D. Cho, Yeong-Jin Choi, 2021, Advanced healthcare materials.

ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation

Jiangwen Zhang, M. Selig, C. Woolf, 2014, Proceedings of the National Academy of Sciences.

Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception

Yasunori Kanaho, Josef M. Penninger, Andreas Zimmer, 2012, PLoS genetics.

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314.

B. Bean, C. Woolf, G. Yao, 2013, Journal of neurophysiology.

Screening for axon regeneration promoting compounds with human iPSC-derived motor neurons

D. Geschwind, C. Gabel, C. Woolf, 2021 .

The properties of neurones recorded in the superficial dorsal horn of the rat spinal cord

C. Woolf, M. Fitzgerald, 1983, The Journal of comparative neurology.

Photochemical activation of TRPA1 channels in neurons and animals

Michael R Hamblin, Robert W. Mills, V. Setola, 2013, Nature chemical biology.

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

S. Sheu, A. Sheridan, C. Pierpaoli, 2018, Cell reports.

Does cyclic AMP have a role in the pathogenesis of fever in the rabbit?

C. Woolf, C. Rosendorff, G. Willies, 1976, Naturwissenschaften.

painisometric contraction and their relation to Kinin peptides in human trapezius muscle during

S. Knardahl, C. Woolf, Nobuko Ito, 2015 .

Partial Peripheral Nerve Injury Promotes a Selective Loss of GABAergic Inhibition in the Superficial Dorsal Horn of the Spinal Cord

Hiroshi Baba, C. Woolf, H. Baba, 2002, The Journal of Neuroscience.

Noxious Inflammation Neural damage and ectopic firing Nociceptive pain Inflammatory pain

A. Patapoutian, C. Woolf, S. Tate, 2022 .

The Voltage-Gated Sodium Channel Nav1.9 Is an Effector of Peripheral Inflammatory Pain Hypersensitivity

I. Chessell, C. Woolf, M. Costigan, 2006, The Journal of Neuroscience.

Faculty Opinions recommendation of Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia.

C. Woolf, 2005 .

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations

Gillian L. Currie, S. McMahon, A. Basbaum, 2015, Pain.

Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

D. Ginty, Jan Drugowitsch, C. Woolf, 2023, bioRxiv.

Axonal injury‐dependent induction of the peripheral benzodiazepine receptor in small‐diameter adult rat primary sensory neurons

C. Woolf, S. Bloechlinger, L. Karchewski, 2004, The European journal of neuroscience.

The sigma‐1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors

C. Woolf, J. Baeyens, E. J. Cobos, 2022, British journal of pharmacology.

Chronic Electrical Nerve Stimulation as a Therapeutic Intervention for Peripheral Nerve Repair

S. Lacour, I. Minev, C. Woolf, 2015 .

The Stress-Induced Atf 3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

M. Sahin, C. Woolf, A. Nardo, 2015 .

The pattern of expression of the voltage-gated sodium channels Nav1.8 and Nav1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models

C. Woolf, I. Decosterd, R. Ji, 2002, Pain.

Basal and touch-evoked fos-like immunoreactivity during experimental inflammation in the rat

C. Woolf, Q. Ma, Qing-Ping Ma, 1996, Pain.

PII: S0304-3959(02)00275-0

C. Woolf, I. Decosterd, A. Allchorne, 2002 .

Neurological infections: something for everyone

C. Woolf, 2013 .

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function.

N. Alp, K. Channon, C. Stefanadis, 2008, Journal of the American College of Cardiology.

123 THE EVOLUTION OF CHRONIC PAIN — POTENTIAL TARGETS FOR PREVENTION

C. Woolf, 2007 .

Reliable screening for a pain-protective haplotype in the GTP cyclohydrolase 1 gene (GCH1) through the use of 3 or fewer single nucleotide polymorphisms.

M. Max, A. Doehring, J. Lötsch, 2007, Clinical chemistry.

Epineural optogenetic activation of nociceptors initiates and amplifies inflammation

S. Lacour, Philipp Schönle, C. Woolf, 2020, Nature Biotechnology.

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.

Sylvia Baedorf Kassis, Stephen A. Goutman, P. Celnik, 2020, JAMA neurology.

Dissecting the precise nature of itch-evoked scratching

Nivanthika K. Wimalasena, C. Woolf, D. Bautista, 2021, Neuron.

Transport and Localization of the DEG/ENaC Ion Channel BNaC1α to Peripheral Mechanosensory Terminals of Dorsal Root Ganglia Neurons

D. Corey, C. Woolf, Ljiljana Žuvela-Jelaska, 2001, The Journal of Neuroscience.

Scalable generation of sensory neurons from human pluripotent stem cells

A. Simeonov, J. Inman, B. Bean, 2023, Stem cell reports.

Implications of recent advances in the understanding of pain pathophysiology for the assessment of pain in patients

C. Woolf, I. Decosterd, 1999, Pain.

The responses recorded in vitro of deep dorsal horn neurons to direct and orthodromic stimulation in the young rat spinal cord

C. Woolf, A. King, L. Urbán, 1988, Neuroscience.

The postnatal development of the ventral root reflex in the rat; a comparative in vivo and in vitro study

C. Woolf, A. King, M. Fitzgerald, 1987, Neuroscience Letters.

Cutaneous receptive field and morphological properties of hamstring flexor alpha‐motoneurones in the rat.

C. Woolf, A. Cook, 1985, The Journal of physiology.

Nerve growth factor levels in developing rat skin: upregulation following skin wounding.

C. Woolf, M. Fitzgerald, M. Reynolds, 1994, Neuroreport.

Hypothalamic heating and cooling in monoamine-depleted rabbits.

C. Woolf, C. Rosendorff, G. Willies, 1975, The American journal of physiology.

The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

S. Tunaru, Seungkyu Lee, C. Woolf, 2017, Scientific Reports.

No Nogo Now Where to Go?

C. Woolf, 2003, Neuron.

Expression of a developmentally regulated, phosphorylated isoform of microtubule-associated protein 1B in regenerating axons of the sciatic nerve

C. Woolf, D. Tonge, P. Gordon-Weeks, 1996, Neuroscience.

Mu and Delta Opioid Receptors Diverge

C. Woolf, 2009, Cell.

Chronic peripheral nerve section diminishes the primary afferent A-fibre mediated inhibition of rat dorsal horn neurones

Patrick D. Wall, Clifford J. Woolf, P. Wall, 1982, Brain Research.

A Conditional Deletion of the NR1 Subunit of the NMDA Receptor in Adult Spinal Cord Dorsal Horn Reduces NMDA Currents and Injury-Induced Pain

F. Gage, S. Heinemann, B. Vissel, 2003, The Journal of Neuroscience.

Silent NMDA receptor-mediated synapses are developmentally regulated in the dorsal horn of the rat spinal cord.

T. Doubell, C. Woolf, H. Baba, 2000, Journal of neurophysiology.

Integrin-Driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

D. Geschwind, J. Fawcett, C. Woolf, 2021, The Journal of Neuroscience.

The Secondary Somatosensory Cortex Gates Mechanical and Thermal Sensitivity

Chinfei Chen, C. Woolf, D. Taub, 2023, bioRxiv.

Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms

J. Steen, C. Gabel, Junjie Zhu, 2015, Neuron.

Injury-Induced Decline of Intrinsic Regenerative Ability Revealed by Quantitative Proteomics

J. Steen, C. Woolf, Zhigang He, 2015, Neuron.

Regeneration of Dorsal Column Fibers into and beyond the Lesion Site following Adult Spinal Cord Injury

C. Woolf, S. Neumann, 1999, Neuron.

Neurophramacology: Endogenous opioid peptides and pain mechanisms: a complex relationship

P. Wall, C. Woolf, 1983, Nature.

Reduced MC4R signaling alters nociceptive thresholds associated with red hair

K. C. Robinson, A. Berényi, C. Woolf, 2021, Science Advances.

Synaptic transmission and plasticity in the superficial dorsal horn.

C. Woolf, H. Baba, K. Moore, 2000, Progress in brain research.

Patients with Chest Pain and Occult Gastroesophageal Reflux Demonstrate Visceral Pain Hypersensitivity which may be Partially Responsive to Acid Suppression

A. Hobson, D. Thompson, Q. Aziz, 2004, American Journal of Gastroenterology.

Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion

I. Singeç, C. Woolf, Andrew R Snavely, 2022, Disease models & mechanisms.

Breaking barriers to novel analgesic drug development

David P. Roberson, B. Bean, C. Woolf, 2017, Nature Reviews Drug Discovery.

Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: Morphology and distribution

C. Woolf, L. Urbán, A. Dray, 1994, The Journal of comparative neurology.

Selectively targeting pain in the trigeminal system

Youngnam Kang, D. Ahn, B. Bean, 2010, PAIN.

Utilization of an HSV-based amplicon vector encoding the axonal marker hPLAP to follow neurite outgrowth in cultured DRG neurons

C. Woolf, R. Seijffers, 2004, Journal of Neuroscience Methods.

Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice

C. Woolf, Alban Latremoliere, M. Costigan, 2019, Arthritis & rheumatology.

Sepiapterin reductase inhibition selectively reduces inflammatory joint pain and increases urinary sepiapterin.

C. Woolf, Alban Latremoliere, M. Costigan, 2019, Arthritis & rheumatology.

Morphology and somatotopic organization of the central terminals of hindlimb hair follicle afferents in the rat lumbar spinal cord

C. Woolf, M. Fitzgerald, P. Shortland, 1989, The Journal of comparative neurology.

Physiological, inflammatory and neuropathic pain.

C. Woolf, 1987, Advances and technical standards in neurosurgery.

Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis

A. Basbaum, S. Eickhoff, R. Dworkin, 2020, Neuroscience & Biobehavioral Reviews.

Convergent neural representations of acute nociceptive pain in healthy volunteers: A large-scale fMRI meta-analysis

A. Basbaum, S. Eickhoff, R. Dworkin, 2019 .

Isolation of Nuclei from Mouse Dorsal Root Ganglia for Single-nucleus Genomics.

C. Woolf, W. Renthal, Lite Yang, 2021, Bio-protocol.

Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion

C. Woolf, L. Barrett, F. Amaya, 2009, Pain.

Sensory innervation of the hairs of the rat hindlimb: A light microscopic analysis

C. Woolf, Catherine Millard, 1988, The Journal of comparative neurology.

A‐fiber sensory input induces neuronal cell death in the dorsal horn of the adult rat spinal cord

R. Coggeshall, C. Woolf, F. White, 2001, The Journal of comparative neurology.

Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons

T. Harkany, R. Konrat, G. Douglas, 2023, bioRxiv.

Structural imaging studies of patients with chronic pain: an anatomic likelihood estimate meta-analysis.

U. Habel, A. Basbaum, S. Eickhoff, 2022, Pain.

Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy

J. Farrar, E. Basch, C. Cleeland, 2011, PAIN®.

Nociceptor neurons promote IgE class switch in B cells

Simmie L. Foster, Seungkyu Lee, C. Woolf, 2021, JCI insight.

Excitatory amino acids increase glycogen phosphorylase activity in the rat spinal cord

C. Woolf, 1987, Neuroscience Letters.

Mapping increased glycogen phosphorylase activity in dorsal root ganglia and in the spinal cord following peripheral stimuli

C. Woolf, M. Chong, Tabassam A. Rashdi, 1985, The Journal of comparative neurology.

What to call the amplification of nociceptive signals in the central nervous system that contribute to widespread pain?

C. Woolf, 2014, PAIN®.

An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice

C. Woolf, A. King, L. Urbán, 1988, Neuroscience Letters.

Development of Neuropathic Pain in the Rat Spared Nerve Injury Model Is Not Prevented by a Peripheral Nerve Block

C. Woolf, M. Papaloïzos, D. Spahn, 2003, Anesthesiology.

Afferent Induced Alterations of Receptive Field Properties

C. Woolf, 1989 .

Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia

J. Lennerz, C. Woolf, L. McIlvried, 2023, bioRxiv.

Nav 1.7 gain-of-function mutation I228M triggers age-dependent nociceptive insensitivity and C-LTMR dysregulation

Nivanthika K. Wimalasena, D. Geschwind, S. Dib-Hajj, 2023, Experimental Neurology.

Human cells and networks of pain: Transforming pain target identification and therapeutic development

S. Waxman, C. Stucky, W. Z. Ray, 2021, Neuron.

Pain

A. Basbaum, C. Woolf, 1999, Current Biology.

A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages

Simmie L. Foster, Xudong Huang, C. Woolf, 2023, Cells.

Failure of naloxone to reverse peripheral transcutaneous electro-analgesia in patients suffering from acute trauma.

C. Woolf, D. Mitchell, R. Myers, 1978, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

Naloxone-reversible peripheral electroanalgesia in intact and spinal rats.

C. Woolf, D. Mitchell, R. Myers, 1977, European journal of pharmacology.

An overview of the mechanisms of hyperalgesia.

C. Woolf, 1995, Pulmonary pharmacology.

Functional plasticity of the flexor withdrawal reflex in the rat following peripheral tissue injury

C. Woolf, 1984, PAIN.

Novel analgesic development: from target to patient or patient to target?

C. Woolf, 2008, Current opinion in investigational drugs.

It Takes More Than Two to Nogo

C. Woolf, S. Bloechlinger, 2002, Science.

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses.

David P. Roberson, D. Ginty, C. Alexandre, 2017, Cell reports.

Time-Resolved Fast Mamm alian Behavior Reveals the Complexity of Protective Pain Responses Graphical

David P. Roberson, D. Ginty, C. Alexandre, 2017 .

Touch and tactile neuropathic pain sensitivity are set by corticospinal projections

Chinfei Chen, C. Alexandre, C. Woolf, 2018, Nature.

Handbook of psychopharmacology, vol. 16 edited by L.L. Iversen, S. D. Iversen and S.H. Snyder, Plenum Press, New York, 1983, 577 pp

C. Woolf, 1985, Pain.

Zinc Reduces the Hyperalgesia and Upregulation of NGF and IL-1β Produced by Peripheral Inflammation in the Rat

C. Woolf, S. Poole, N. Saadé, 1996, Neuropharmacology.

Identiﬁcation and characterization of a novel human vanilloid receptor-like protein, VRL-2

P. Sanseau, C. G. See, P. Anand, 2022 .

Delayed sympathetic dependence in the spared nerve injury ( SNI ) model of neuropathic pain

C. Woolf, I. Decosterd, A. Allchorne, 2016 .

Histocal Profile: Patrick D. Wall, DM, FRCP, FRS

C. Woolf, 1992 .

Lamina-specific alteration of C-fibre evoked activity by morphine in the dorsal horn of the rat spinal cord

C. Woolf, M. Fitzgerald, 1981, Neuroscience Letters.

Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-caliber afferents is a predictor of action potential windup in rat spinal neurons in vitro.

C. Woolf, L. Sivilotti, C. Woolf, 1993, Journal of neurophysiology.

Neonatal capsaicin treatment induces invasion of the substantia gelatinosa by the terminal arborizations of hair follicle afferents in the rat dorsal horn

C. Woolf, M. Fitzgerald, C. Molander, 1990, The Journal of comparative neurology.

Effects of capsaicin on receptive fields and on inhibitions in rat spinal cord

P. D. Wall, P. Wall, C. Woolf, 1982, Experimental Neurology.

The progressive tactile hyperalgesia induced by peripheral inflammation is nerve growth factor dependent

C. Woolf, Q. Ma, Qing-Ping Ma, 1997, Neuroreport.

The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons

L. Benowitz, C. Woolf, R. Kawaguchi, 2023, Science Translational Medicine.

Cytokines, nerve growth factor and inflammatory hyperalgesia: the contribution of tumour necrosis factor α

C. Woolf, S. Poole, B. Safieh-Garabedian, 1997, British journal of pharmacology.

Peripheral cell types contributing to the hyperalgesic action of nerve growth factor in inflammation

C. Woolf, S. Poole, Q. Ma, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The Secondary Somatosensory Cortex Gates Mechanical and Thermal Sensitivity

Chinfei Chen, C. Woolf, D. Taub, 2023, Research square.

Perceptual wind-up in the human oesophagus is enhanced by central sensitisation

A. Hobson, Q. Aziz, C. Woolf, 2006, Gut.

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Allon M. Klein, M. Kirschner, V. Li, 2017 .

The role of nitric oxide and cutaneous nerves in the erythema of psoriasis and atopic eczema

C. Woolf, A. Bewley, J. Foreman, 1994 .

Opioids in Pain Control: Pre-emptive Analgesia by Opioids

C. Woolf, L. Bromley, 1998 .

Reorganization of central terminals of myelinated primary afferents in the rat dorsal horn following peripheral axotomy

R. Coggeshall, T. Doubell, J. Ridings, 1995, The Journal of comparative neurology.

What we don't know about pain

P. Wall, C. Woolf, Patrick D. Wall, 1980, Nature.

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Allon M. Klein, M. Kirschner, V. Li, 2017 .

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Allon M. Klein, M. Kirschner, V. Li, 2018 .

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Allon M. Klein, M. Kirschner, V. Li, 2017 .

Axonal regeneration from injured dorsal roots into the spinal cord of adult rats

C. Woolf, C. Woolf, P. Anderson, 1999, The Journal of comparative neurology.

Central terminations of cutaneous mechanoreceptive afferents in the rat lumbar spinal cord

C. Woolf, 1987, The Journal of comparative neurology.

Intrinsic versus extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: The influence of a peripheral nerve graft

C. Woolf, M. Turmaine, C. Woolf, 1996, The Journal of comparative neurology.

Neurite outgrowth and GAP‐43 mRNA expression in cultured adult rat dorsal root ganglion neurons: Effects of NGF or prior peripheral axotomy

P. Emson, C. Woolf, J. Winter, 1994, Journal of neuroscience research.

C-primary afferent fibre mediated inhibitions in the dorsal horn of the decerebrate-spinal rat

C. Woolf, 2004, Experimental Brain Research.

Touch and Tactile Neuropathic Pain Sensitivity Are Set by Corticospinal Projections

Chinfei Chen, C. Alexandre, C. Woolf, 2018, Nature.

Exploiting microarrays to reveal differential gene expression in the nervous system

C. Woolf, M. Costigan, R. Griffin, 2003, Genome Biology.

Neuronal plasticity: increasing the gain in pain.

C. Woolf, M. Salter, Clifford J. Woolf, 2000, Science.

Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro.

C. Woolf, L. Sivilotti, C. Woolf, 1993, Journal of neurophysiology.

Activity‐Dependent Changes in Rat Ventral Horn Neurons in vitro; Summation of Prolonged Afferent Evoked Postsynaptic Depolarizations Produce a D‐2‐Amino‐5‐Phosphonovaleric Acid Sensitive Windup

C. Woolf, A. King, C. Woolf, 1990, The European journal of neuroscience.

Characterization of the cutaneous input to the ventral horn in vitro using the isolated spinal cord-hind limb preparation

C. Woolf, A. King, S. Thompson, 1990, Journal of Neuroscience Methods.

Do opioid peptides mediate a presynaptic control of C-fibre transmission in the rat spinal cord?

C. Woolf, M. Fitzgerald, 1982, Neuroscience Letters.

Towards a mechanism-based approach to pain diagnosis

C. Woolf, R. Mannion, Daniel Vardeh, 2016 .

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer

E. McNeill, K. Channon, A. Waisman, 2018, Nature.

The Stress-Induced Atf3-Gelsolin Cascade Underlies Dendritic Spine Deficits in Neuronal Models of Tuberous Sclerosis Complex

Zehua Chen, M. Sahin, C. Woolf, 2015, The Journal of Neuroscience.

ATF3 expression improves motor function in the ALS mouse model by promoting motor neuron survival and retaining muscle innervation

Jiangwen Zhang, M. Selig, C. Woolf, 2014, Proceedings of the National Academy of Sciences.

Persistent postsurgical pain: risk factors and prevention

H. Kehlet, C. Woolf, T. Jensen, 2006, The Lancet.

Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

L. Arendt-Nielsen, L. F. Frey Law, M. Nevitt, 2015, Arthritis & rheumatology.

Overcoming inhibition

Clifford J. Woolf, C. Woolf, 1995, Nature.

Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion

C. Woolf, L. Barrett, F. Amaya, 2009, Pain.

Enhanced neuronal regeneration in the CAST/Ei mouse strain is linked to expression of differentiation markers after injury

K. Kosik, G. Coppola, Michio W. Painter, 2017, bioRxiv.

Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes

Simmie L. Foster, K. Tracey, M. Ochani, 2016, Bioelectronic medicine.

Central sensitization: Implications for the diagnosis and treatment of pain

C. Woolf, 2011, PAIN.

Putting the Spinal Cord Together Again

C. Woolf, K. Mizuno, O. Behar, 2000, Neuron.

A dissociation between temperature regulation and fever in the rabbit.

D. Borsook, C. Woolf, C. Rosendorff, 1977, The Journal of physiology.

Axotomy increases glycogen phosphorylase activity in motoneurones

A. Ainsworth, C. Woolf, M. Chong, 1984, Neuroscience.

Development of a PET radioligand for α2δ-1 subunit of calcium channels for imaging neuropathic pain

C. Woolf, Nick A. Andrews, Yu-Peng Zhou, 2022, bioRxiv.

Effects of cutaneous nerve and intraspinal conditioning of C‐fibre afferent terminal excitability in decerebrate spinal rats.

C. Woolf, M. Fitzgerald, 1981, The Journal of physiology.

The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

S. Tunaru, Seungkyu Lee, C. Woolf, 2017, Scientific Reports.

Prolonged primary afferent induced alterations in dorsal horn neurones, an intracellular analysis in vivo and in vitro.

C. Woolf, A. King, S. Thompson, 1988, Journal de physiologie.

Two independent mouse lines carrying the Nav1.7-I228M gain-of-function variant display DRG neuron hyperexcitability but a minimal pain phenotype.

Nivanthika K. Wimalasena, S. Waxman, C. Woolf, 2020, Pain.

CNS injury: IL-33 sounds the alarm.

Simmie L. Foster, C. Woolf, S. Talbot, 2015, Immunity.

Inhibitory controls on thermal neurones in the spinal trigeminal nucleus of cats and rats

N. Dawson, C. Woolf, C. Woolf, 1981, Brain Research.