Emily F. Ruff

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

Sonya M. Hanson, Steven K. Albanese, Julie M. Behr, 2017, bioRxiv.

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

Sonya M. Hanson, Steven K. Albanese, Julie M. Behr, 2017, bioRxiv.

Mechanism of transcription initiation and promoter escape by E. coli RNA polymerase

Emily F. Ruff, M. Record, I. Shkel, 2017, Proceedings of the National Academy of Sciences.

Key roles of the downstream mobile jaw of Escherichia coli RNA polymerase in transcription initiation.

Emily F. Ruff, M. Record, I. Artsimovitch, 2012, Biochemistry.

E. coli RNA Polymerase Determinants of Open Complex Lifetime and Structure.

Emily F. Ruff, M. Record, I. Artsimovitch, 2015, Journal of molecular biology.

Initial Events in Bacterial Transcription Initiation

Emily F. Ruff, M. Record, I. Artsimovitch, 2015, Biomolecules.

Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states

Joseph M. Muretta, David D. Thomas, Emily F. Ruff, 2018, Proceedings of the National Academy of Sciences.

A water-mediated allosteric network governs activation of Aurora kinase A.

Julie M. Behr, J. Chodera, Emily F. Ruff, 2017, Nature chemical biology.

1 A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop 1 phosphorylation 2 3

Sonya M. Hanson, Julie M. Behr, Joseph M. Muretta, 2017 .