B. Puig

发表

Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models

I. Ferrer, M. Dierssen, M. Barrachina, 2005, Neurobiology of Disease.

Immediate Early Genes, Inducible Transcription Factors and Stress Kinases in Alzheimer's Disease

I. Ferrer, B. Puig, G. Santpere, 2006 .

Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat

B. Puig, I. Ferrer, I. Ferrer, 2002, Acta Neuropathologica.

Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies

I. Ferrer, M. Barrachina, B. Puig, 2001, Journal of Neural Transmission.

Cell death signaling in the cerebellum in Creutzfeldt-Jakob disease

B. Puig, I. Ferrer, 2001, Acta Neuropathologica.

Abnormal Sp1 transcription factor expression in Alzheimer disease and tauopathies

B. Puig, G. Santpere, I. Ferrer, 2006, Neuroscience Letters.

Misfolding leads the way to unraveling signaling pathways in the pathophysiology of prion diseases

B. Puig, M. Glatzel, H. Altmeppen, 2016, Prion.

Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke

B. Puig, T. Magnus, H. Altmeppen, 2020, Cells.

Primary progressive aphasia as the initial manifestation of corticobasal degeneration and unusual tauopathies

I. Ferrer, M. Boada, B. Puig, 2003, Acta Neuropathologica.

Amyloid-β deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AβPP mRNA isoforms containing the Kunitz protease inhibitor

I. Ferrer, M. Barrachina, B. Puig, 2005, Neurochemistry International.

Selective PrP‐like protein, doppel immunoreactivity in dystrophic neurites of senile plaques in Alzheimer's disease

I. Ferrer, B. Puig, R. Blanco, 2004, Neuropathology and applied neurobiology.

GluR2/3, NMDAepsilon1 and GABAA receptors in Creutzfeldt-Jakob disease.

I Ferrer, I. Ferrer, B. Puig, 2003, Acta neuropathologica.

Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein

B. Puig, M. Damme, M. Glatzel, 2022, Cell and Tissue Research.

SARS-CoV-2 could be spread through hospital medication dispensed to patients

B. Puig, R. Maldonado, J. Masclans, 2021, Medicine.

Individual and regional variations of phospho-tau species in progressive supranuclear palsy

B. Puig, I. Ferrer, M. Rey, 2005, Acta Neuropathologica.

Fas and Fas ligand expression in Alzheimer's disease

B. Puig, J. Krupiński, I. Ferrer, 2001, Acta Neuropathologica.

Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes

O. Kretz, B. Puig, M. Alawi, 2022, Cellular and Molecular Life Sciences.

Ubiquitin-negative mini-pick-like bodies in the dentate gyrus in p301l tauopathy.

E. Tolosa, I. Ferrer, M. Boada, 2004, Journal of Alzheimer's disease : JAD.

Brain Protein Preservation Largely Depends on the Postmortem Storage Temperature: Implications for Study of Proteins in Human Neurologic Diseases and Management of Brain Banks: A BrainNet Europe Study

H. Budka, H. Kretzschmar, T. Arzberger, 2007, Journal of neuropathology and experimental neurology.

Tau phosphorylation and kinase activation in familial tauopathy linked to deln296 mutation

E. Tolosa, I. Ferrer, P. Pástor, 2003, Neuropathology and applied neurobiology.

Multiple cervical artery dissections

P. Pástor, B. Puig, I. Ferrer, 2005, Neurology.

Clusterin solubility and aggregation in Creutzfeldt-Jakob disease

B. Puig, I. Ferrer, R. Blanco, 2004, Acta Neuropathologica.

Release of VAMP5‐positive extracellular vesicles by retinal Müller glia in vivo

B. Puig, S. Hauck, B. Giebel, 2022, bioRxiv.

Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein

W. Jackson, P. Saftig, B. Puig, 2018, Molecular Neurodegeneration.

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo

B. de Strooper, P. Saftig, B. Puig, 2011, Molecular Neurodegeneration.

VDAC and ERα interaction in caveolae from human cortex is altered in Alzheimer's disease

G. Meyer, C. Ramírez, B. Puig, 2009, Molecular and Cellular Neuroscience.

Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick’s disease

B. Puig, I. Ferrer, F. Viñals, 2004, Acta Neuropathologica.

N-Glycans and Glycosylphosphatidylinositol-Anchor Act on Polarized Sorting of Mouse PrPC in Madin-Darby Canine Kidney Cells

B. Puig, M. Glatzel, T. Braulke, 2011, PloS one.

Retinal regions shape human and murine Müller cell proteome profile and functionality

M. Samardzija, U. Schlötzer-Schrehardt, K. Franze, 2022, Glia.

Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick’s disease

B. Puig, G. Santpere, I. Ferrer, 2006, Acta Neuropathologica.

Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat

B. Puig, I. Ferrer, Isidro Ferrer, 2002, Neuroscience Letters.

Low molecular weight species of tau in Alzheimer's disease are dependent on tau phosphorylation sites but not on delayed post-mortem delay in tissue processing

B. Puig, G. Santpere, I. Ferrer, 2006, Neuroscience Letters.

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies

I. Ferrer, B. Puig, I. Ferrer, 2001, Journal of Neural Transmission.

Molecular Communication of a Dying Neuron in Stroke

B. Puig, T. Magnus, Santra Brenna, 2018, International journal of molecular sciences.

Phosphorylated Map Kinase (ERK1, ERK2) Expression is Associated with Early Tau Deposition in Neurones and Glial Cells, but not with Increased Nuclear DNA Vulnerability and Cell Death, in Alzheimer Disease, Pick's Disease, Progressive Supranuclear Palsy and Corticobasal Degeneration

I. Ferrer, B. Puig, R. Blanco, 2001, Brain pathology.

Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies.

I Ferrer, I. Ferrer, T. Gómez-Isla, 2005, Current Alzheimer research.

Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective

B. Puig, C. Krisp, T. Magnus, 2021, International journal of molecular sciences.

Generation and Function of Non-cell-bound CD73 in Inflammation

B. Puig, H. Mittrücker, T. Magnus, 2019, Front. Immunol..

Phosphorylated c‐MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration

I. Ferrer, B. Puig, R. Blanco, 2001, Neuropathology and applied neurobiology.

Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processes

O. Kretz, B. Puig, M. Alawi, 2021, bioRxiv.

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

B. Puig, C. Meyer-Schwesinger, R. Reimer, 2021, Nature Communications.

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake

H. Schlüter, B. Puig, M. Glatzel, 2020, Journal of extracellular vesicles.

Brain-Derived Extracellular Vesicles are Highly Enriched in the Prion Protein and Its C1 Fragment: Relevance for Cellular Uptake and Implications in Stroke

B. Puig, M. Glatzel, Carola Schneider, 2019, bioRxiv.

Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein

W. Jackson, P. Saftig, B. Puig, 2018, Molecular Neurodegeneration.

BetaII-tubulin and phospho-tau aggregates in Alzheimer's disease and Pick's disease.

B. Puig, J. Ávila, I. Ferrer, 2005, Journal of Alzheimer's disease : JAD.

GluR2/3, NMDAε1 and GABAA receptors in Creutzfeldt-Jakob disease

B. Puig, I. Ferrer, 2003, Acta Neuropathologica.

Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease

I. Zerr, B. Puig, I. Ferrer, 2021, Molecular neurodegeneration.

Proteolytic processing of the prion protein in health and disease.

B. Puig, M. Glatzel, S. Krasemann, 2012, American journal of neurodegenerative disease.

Cleaved caspase-3, caspase-7 and poly (ADP-ribose) polymerase are complementarily but differentially expressed in human medulloblastomas

B. Puig, I. Ferrer, A. Tortosa, 2001, Neuroscience Letters.

Prion protein expression in senile plaques in Alzheimer's disease

I. Ferrer, B. Puig, I. Ferrer, 2000, Acta Neuropathologica.

GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice

B. Puig, M. Glatzel, T. Magnus, 2019, PLoS pathogens.

Lipid alterations in lipid rafts from Alzheimer's disease human brain cortex.

B. Puig, G. Santpere, I. Ferrer, 2010, Journal of Alzheimer's disease : JAD.

Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

S. Arlt, B. Puig, I. Ferrer, 2016, Journal of neuropathology and experimental neurology.

Prion protein deposition and abnormal synaptic protein expression in the cerebellum in Creutzfeldt–Jakob disease

B. Puig, E. Martí, I. Ferrer, 2000, Neuroscience.

Abnormal synaptic protein expression and cell death in murine scrapie

A. Aguzzi, C. Acín, J. Badiola, 2002, Acta Neuropathologica.

Roles of endoproteolytic α‐cleavage and shedding of the prion protein in neurodegeneration

B. Puig, M. Glatzel, S. Krasemann, 2013, The FEBS journal.

Shedding light on prion disease

B. Puig, M. Glatzel, S. Krasemann, 2015, Prion.

Expression of stress‐activated kinases c‐Jun N‐terminal kinase (SAPK/JNK‐P) and p38 kinase (p38‐P), and tau hyperphosphorylation in neurites surrounding βA plaques in APP Tg2576 mice

T. Gómez-Isla, B. Puig, E. Dalfo, 2004, Neuropathology and applied neurobiology.

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice

I. Ferrer, T. Gómez-Isla, B. Puig, 2005, Neurobiology of Disease.

A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease

K. Blennow, B. Hyman, B. de Strooper, 2020, Acta Neuropathologica.

The GPI-anchoring of PrP

B. Puig, M. Glatzel, H. Altmeppen, 2014, Prion.

Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease

F. Lopera, B. Puig, I. Ferrer, 2011, Brain pathology.

Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies

S. Hornemann, A. Aguzzi, I. Zerr, 2021, Science advances.

Phosphorylated Protein Kinases Associated with Neuronal and Glial Tau Deposits in Argyrophilic Grain Disease

I. Ferrer, M. Barrachina, B. Puig, 2003, Brain pathology.

Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains

M. Barrachina, B. Puig, I. Ferrer, 2002, Acta Neuropathologica.

Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration

I. Ferrer, M. Barrachina, B. Puig, 2002, Acta Neuropathologica.

RETRACTED: Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer’s disease and cerebral amyloid angiopathy

B. Puig, G. Santpere, I. Ferrer, 2007, Neuroscience.

Oxidative damage of 14-3-3 zeta and gamma isoforms in Alzheimer's disease and cerebral amyloid angiopathy.

B. Puig, G. Santpere, I. Ferrer, 2007, Neuroscience.

βII-tubulin and phospho-tau aggregates in Alzheimer's disease and Pick's disease

I. Ferrer, B. Puig, J. Ávila, 2005 .

Metabotropic glutamate receptor/phospholipase C pathway: A vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex

I. Ferrer, B. Puig, E. Dalfo, 2005, Neuroscience.

The sheddase ADAM10 is a potent modulator of prion disease

P. Liberski, P. Saftig, B. Puig, 2015, eLife.

Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation

B. Puig, M. Glatzel, F. Koch-Nolte, 2020, Molecular Neurobiology.

Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts

B. Puig, M. Glatzel, H. Altmeppen, 2023, Neural regeneration research.

Ligands binding to the cellular prion protein induce its protective proteolytic release with therapeutic potential in neurodegenerative proteinopathies

S. Hornemann, A. Aguzzi, I. Zerr, 2021, bioRxiv.

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

B. Puig, H. Wille, M. Glatzel, 2016, Scientific Reports.

Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

Yohan Kim, B. Puig, M. Schweizer, 2023, bioRxiv.