Umashankar Vetrivel

发表

Identification of potential drugs targeting L,L‐diaminopimelate aminotransferase of Chlamydia trachomatis: An integrative pharmacoinformatics approach

Anupriya Sadhasivam, Umashankar Vetrivel, 2018, Journal of cellular biochemistry.

Understanding the Uptake Mechanism and Interaction Potential of the Designed Peptide and Preparation of Composite Fiber Matrix for Fungal Keratitis

Umashankar Vetrivel, Hemavathy Nagarajan, P. Padmanabhan, 2020, ACS omega.

Genome-wide codon usage profiling of ocular infective Chlamydia trachomatis serovars and drug target identification

Anupriya Sadhasivam, Umashankar Vetrivel, 2018, Journal of biomolecular structure & dynamics.

Peptidomimetics Based Inhibitor Design for HIV 1 gp120 Attachment Protein

Umashankar Vetrivel, Umashankar Vetrivel, N. Nagarajan, 2009 .

Microsecond Simulation of the Proteoglycan-like Region of Carbonic Anhydrase IX and Design of Chemical Inhibitors Targeting pH Homeostasis in Cancer Cells

Arun John, Muthukumaran Sivashanmugam, S. Natarajan, 2020, ACS omega.

A novel in silico approach to identify potential therapeutic targets in human bacterial pathogens

Umashankar Vetrivel, G. Subramanian, S. Dorairaj, 2011, The HUGO Journal.

Deciphering ophthalmic adaptive inhibitors targeting RON4 of Toxoplasma gondii: An integrative in silico approach

Umashankar Vetrivel, Hemavathy Nagarajan, 2018, Life sciences.

Identification and Insilico Analysis of Retinoblastoma Serum microRNA Profile and Gene Targets Towards Prediction of Novel Serum Biomarkers

Umashankar Vetrivel, V. Khetan, S. Krishnakumar, 2013, Bioinformatics and biology insights.

Agonistic effect of polyunsaturated fatty acids (PUFAs) and its metabolites on brain-derived neurotrophic factor (BDNF) through molecular docking simulation

Umashankar Vetrivel, U. Das, S. Ravichandran, 2012, Lipids in Health and Disease.

Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

Umashankar Vetrivel, A. Narayanasamy, Shalini Muralikumar, 2017, Lipids in Health and Disease.

In silico docking of phytocompounds to identify potent inhibitors of signaling pathways involved in prostate cancer

Umashankar Vetrivel, Sumathy Arockiasamy, B. Jonnalagadda, 2020, Journal of biomolecular structure & dynamics.

Tear specific potential protein biomarker identification by 2D-DIGE based proteomics in Dry eye syndrome associated with Rheumatoid Arthritis

Umashankar Vetrivel, U. Tatu, P. Padmanabhan, 2013 .

Integrative study of gene expression datasets in retinal samples of Diabetic Retinopathy.

Umashankar Vetrivel, Shanmuganathan Seetharaman, K.Elumalai Kuppan, 2022, Experimental eye research.

Whole-Genome Sequencing and Mutation Analysis of Two Extensively Drug-Resistant Sputum Isolates of Mycobacterium tuberculosis (VRFCWCF XDRTB 232 and VRFCWCF XDRTB 1028) from Chennai, India

Umashankar Vetrivel, S. Rathinam, Meenakshi Narasimhan, 2014, Genome Announcements.

Modulation of multidrug resistance 1 expression and function in retinoblastoma cells by curcumin

Umashankar Vetrivel, Sathyabaarathi Ravichandran, S. Krishnakumar, 2013, Journal of pharmacology & pharmacotherapeutics.

Chemoprofiling and insilico prioritization of bioactive compounds from Laetiporus versisporus (Lloyd) Imazeki reveals potential Bcl-2 inhibitor

Umashankar Vetrivel, S. A., Shoba G, 2022, Journal of biomolecular structure & dynamics.

Synthesis and Characterization of a Novel Peptide Targeting Human Tenon Fibroblast Cells To Modulate Fibrosis: An Integrated Empirical Approach.

D. Gopal, Umashankar Vetrivel, Hemavathy Nagarajan, 2022, ACS pharmacology & translational science.

Design of human immunodeficiency virus-1 neutralizing peptides targeting CD4-binding site: An integrative computational biologics approach

Umashankar Vetrivel, L. Hanna, Sandhya Vivekanandan, 2022, Frontiers in Medicine.

Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach.

Umashankar Vetrivel, Hemavathy Nagarajan, Saratha Narayanaswamy, 2020, Mutation research.

Deciphering novel potential antibacterial targets in tomato pathogen Ralstonia solanacearum GMI1000 through integration of in silico subtractive genomics, codon usage and protein–protein interaction analyses

Umashankar Vetrivel, G. Subramanian, Mohamed Imran Mohamedyousuff, 2022, Australasian Plant Pathology.

Hepatitis C Virus NS3/4A Inhibition and Host Immunomodulation by Tannins from Terminalia chebula: A Structural Perspective

Umashankar Vetrivel, Subarna Roy, V. Patil, 2022, Molecules.

Umashankar Vetrivel, G. Subramanian, Mohamed Imran Mohamedyousuff, 2022, Australasian Plant Pathology.

In silico analysis and prioritization of drug targets in Fusarium solani.

K. Therese, Muthukumaran Sivashanmugam, Umashankar Vetrivel, 2015, Medical hypotheses.

Elucidating the Therapeutic Potential of Cell-Penetrating Peptides in Human Tenon Fibroblast Cells

D. Gopal, Umashankar Vetrivel, A. Chatterjee, 2022, ACS omega.

Inhibition of IKKβ by celastrol and its analogues – an in silico and in vitro approach

Umashankar Vetrivel, S. Natarajan, S. Samuel, 2016, Pharmaceutical biology.

IN SILICO SCREENING OF POTENT PPARGAMMA AGONISTS AMONG NATURAL ANTICANCER COMPOUNDS OF INDIAN ORIGIN

Umashankar Vetrivel, T. Loganathan, S. Pannerselvam, 2016 .

Multilevel Precision-Based Rational Design of Chemical Inhibitors Targeting the Hydrophobic Cleft of Toxoplasma gondii Apical Membrane Antigen 1 (AMA1)

H. Madhavan, Umashankar Vetrivel, B. Mahalakshmi, 2016, Genomics & informatics.

Comparative docking of dual conformations in human fatty acid synthase thioesterase domain reveals potential binding cavity for virtual screening of ligands

P. R. Deepa, Umashankar Vetrivel, Krishnakumar Subramanian, 2017, Journal of biomolecular structure & dynamics.

KinomeRun: An interactive utility for kinome target screening and interaction fingerprint analysis towards holistic visualization on kinome tree

Umashankar Vetrivel, Samdani Ansar, Umashankar Vetrivel, 2020, Chemical biology & drug design.

Structure-based design of small molecule and peptide inhibitors for selective targeting of ROCK1: an integrative computational approach

Umashankar Vetrivel, Samdani Ansar, 2021, Journal of biomolecular structure & dynamics.

POAP: A GNU parallel based multithreaded pipeline of open babel and AutoDock suite for boosted high throughput virtual screening

Umashankar Vetrivel, A. Samdani, Umashankar Vetrivel, 2018, Comput. Biol. Chem..

ACUA: A software tool for automated codon usage analysis

Umashankar Vetrivel, Vijayakumar Arunkumar, Sudarsanam Dorairaj, 2007, Bioinformation.

Microsecond scale sampling of Egr-1 conformational landscape to decipher the impact of its disorder regions on structure–function relationship

Umashankar Vetrivel, Hemavathy Nagarajan, 2020 .

ELUCIDATION OF IRON BINDING PATTERNS THROUGH INSILICO APPROACHES IN HUMAN IRON BINDING PROTEINS

Sulochana, Muthukumaran Sivashanmugam, Umashankar Vetrivel, 2013 .

Targeting CD44, ABCG2 and CD133 markers using aptamers: in silico analysis of CD133 extracellular domain 2 and its aptamer

Umashankar Vetrivel, R. Kanwar, J. Kanwar, 2016 .

PCOSDB: PolyCystic Ovary Syndrome Database for manually curated disease associated genes

Umashankar Vetrivel, Vijayalakshmi Melanathuru, D. Munuswamy, 2016, Bioinformation.

Retinoschisis and Norrie disease: a missing link

Umashankar Vetrivel, Hemavathy Nagarajan, J. Arunachalam, 2021, BMC research notes.

Understanding variable disease severity in X-linked retinoschisis: Does RS1 secretory mechanism determine disease severity?

R. Raman, Muthukumaran Sivashanmugam, Umashankar Vetrivel, 2018, PloS one.

Elucidation Of Structure - Function Relationship In Families Of Copper Binding Proteins In Homo Sapiens – A Bioinformatics Approach

Umashankar Vetrivel, V. Natarajan, N. MathangiJayaramanSudarshana, 2012 .

Anticancer Activity of Sida cordifolia L., – Insilico approach

Umashankar Vetrivel, M. Muthuraman, S. Sinsinwar, 2017 .

Pharmacoinformatics Analysis Reveals Flavonoids and Diterpenoids from Andrographis paniculata and Thespesia populnea to Target Hepatocellular Carcinoma Induced by Hepatitis B Virus

Umashankar Vetrivel, Subarna Roy, S. Jalalpure, 2022, Applied Sciences.

Deciphering potential inhibitors targeting THI4 of Fusarium solani sp. to combat fungal keratitis: An integrative computational approach

Hemavathy Nagarajan, P. Deepika Lakshmi, Umashankar Vetrivel, 2020, Comput. Biol. Chem..

Structural insights on druggable hotspots in CD147: A bull's eye view.

Umashankar Vetrivel, Krishnakumar Subramanian, Sowmya Parameswaran, 2019, Life sciences.

Demystifying the pH dependent conformational changes of human heparanase pertaining to structure–function relationships: an in silico approach

Hemavathy Nagarajan, Umashankar Vetrivel, Umashankar Vetrivel, 2018, Journal of Computer-Aided Molecular Design.

In vitro and In silico studies on inhibitory effects of curcumin on multi drug resistance associated protein (MRP1) in retinoblastoma cells

Umashankar Vetrivel, Sathyabaarathi Ravichandran, S. Krishnakumar, 2012, Bioinformation.

Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

Umashankar Vetrivel, A. Narayanasamy, Shalini Muralikumar, 2017, Lipids in Health and Disease.

RNA-Seq of untreated wastewater to assess COVID-19 and emerging and endemic viruses for public health surveillance

A. Tarr, C. Hill, R. Kashyap, 2023, The Lancet regional health. Southeast Asia.

COMPUTATIONAL DOCKING STUDIES REVEAL THE MOST POTENTIAL INHIBITORY BINDING MODE OF DEMETHOXYLATED AND REDUCED CURCUMIN COMPOUNDS ON LUNG RESISTANCE PROTEIN

Umashankar Vetrivel, S. Krishnakumar, Seethalakshmi Sreenivasan, 2014 .

Phylogenetic comparison of exonic US4, US7 and UL44 regions of clinical herpes simplex virus type 1 isolates showed lack of association between their anatomic sites of infection and genotypic/sub genotypic classification

Umashankar Vetrivel, Sathyabaarathi Ravichandran, M. Jambulingam, 2012, Virology Journal.

Design of inhibitory peptide targeting Toxoplasma gondii RON4‐human β‐tubulin interactions by implementing structural bioinformatics methods

Umashankar Vetrivel, Hemavathy Nagarajan, Indhuja Thirumudi, 2018, Journal of cellular biochemistry.

Probing the biophysical interaction between Neocarzinostatin toxin and EpCAM RNA aptamer.

Umashankar Vetrivel, R. Kanwar, J. Kanwar, 2016, Biochemical and biophysical research communications.

Virtual screening and multilevel precision-based prioritisation of natural inhibitors targeting the ATPase domain of human DNA topoisomerase II alpha.

Umashankar Vetrivel, Srujana Chitipothu, Sharada Ramasubramanyan, 2023, Journal of biomolecular structure & dynamics.

Deciphering the structural and functional impact of missense mutations in Egr1-DNA interacting interface: an integrative computational approach

Umashankar Vetrivel, Hemavathy Nagarajan, 2021, Journal of biomolecular structure & dynamics.

Importance of ABC transporters in different tissues

Umashankar Vetrivel, G. Subramanian, 2014, Drug metabolism and drug interactions.

Membrane dynamics simulation and virtual screening reveals potential dual natural inhibitors of endothelin receptors for targeting glaucomatous condition.

Umashankar Vetrivel, Hemavathy Nagarajan, 2021, Life sciences.

Molecular characterization and re-interpretation of HNF1A variants identified in Indian MODY subjects towards precision medicine

V. Radha, Umashankar Vetrivel, Sampathkumar Ranganathan, 2023, Frontiers in endocrinology.

Detection of novel coupled mutations in the katG gene (His276Met, Gln295His and Ser315Thr) in a multidrug-resistant Mycobacterium tuberculosis strain from Chennai, India, and insight into the molecular mechanism of isoniazid resistance using structural bioinformatics approaches.

K. Therese, Muthukumaran Sivashanmugam, Umashankar Vetrivel, 2011, International journal of antimicrobial agents.

Coding-Complete Genome Sequences of NITMA1086 and NITMA1139, Two SARS-CoV-2 Isolates from Belagavi District, Karnataka State, India, Harboring the D614G Mutation

Umashankar Vetrivel, D. Harish, I. Singh, 2021, Microbiology Resource Announcements.

RNA-Seq of untreated wastewater to assess COVID-19 and emerging and endemic viruses for public health surveillance

A. Tarr, R. Kashyap, Umashankar Vetrivel, 2023, The Lancet regional health. Southeast Asia.

Structural analysis and molecular dynamics simulation studies of HIV-1 antisense protein predict its potential role in HIV replication and pathogenesis

Umashankar Vetrivel, Sujata Roy, S. Hassan, 2023, Frontiers in Microbiology.

PepVis: An integrated peptide virtual screening pipeline for ensemble and flexible docking protocols

Umashankar Vetrivel, Samdani Ansar, Umashankar Vetrivel, 2019, Chemical biology & drug design.

Agonistic effect of polyunsaturated fatty acids (PUFAs) and its metabolites on brain-derived neurotrophic factor (BDNF) through molecular docking simulation

Umashankar Vetrivel, U. Das, S. Ravichandran, 2012, Lipids in Health and Disease.

Multilayer precision-based screening of potential inhibitors targeting Mycobacterium tuberculosis acetate kinase using in silico approaches.

Umashankar Vetrivel, Hemavathy Nagarajan, J. Jeyaraman, 2023, Computational biology and chemistry.

Deciphering the conformational transitions of LIMK2 active and inactive states to ponder specific druggable states through microsecond scale molecular dynamics simulation

V. Umashankar, Umashankar Vetrivel, Hemavathy Nagarajan, 2022, Journal of Computer-Aided Molecular Design.

Identification of potential drugs targeting L,L‐diaminopimelate aminotransferase of Chlamydia trachomatis: An integrative pharmacoinformatics approach

Anupriya Sadhasivam, Umashankar Vetrivel, 2018, Journal of cellular biochemistry.

Virtual screening studies reveal linarin as a potential natural inhibitor targeting CDK4 in retinoblastoma

Muthukumaran Sivashanmugam, Umashankar Vetrivel, C. Raghunath, 2013, Journal of pharmacology & pharmacotherapeutics.

pH-Dependent conformational stability of SpeB from Thermus thermophilus HB8: insights from molecular dynamics simulation

Umashankar Vetrivel, J. Jeyakanthan, Alagesan Karthika, 2023, Molecular Simulation.

Biochemical and biophysical characterization of biosynthetic arginine decarboxylase from Thermus thermophilus.

Umashankar Vetrivel, Hemavathy Nagarajan, J. Jeyaraman, 2024, Journal of biomolecular structure & dynamics.

Unveiling the intricacies of allosteric regulation in aspartate kinase from the Wolbachia endosymbiont of Brugia Malayi: Mechanistic and therapeutic insights.

Umashankar Vetrivel, Hemavathy Nagarajan, J. Jeyakanthan, 2024, International journal of biological macromolecules.

orced expression of microRNA-221-3p exerts protective effects against manganese-induced cytotoxicity in human lung epithelial cells.

Umashankar Vetrivel, S. Rajasekaran, Sneha Bhandari, 2024, Toxicology and applied pharmacology.