J. Bouwstra

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Reduced skin barrier function parallels abnormal stratum corneum lipid organization in patients with lamellar ichthyosis.

A. Lavrijsen, J. Bouwstra, G. Gooris, 1995, The Journal of investigative dermatology.

Focus on skin as a possible port of entry for solid nanoparticles and the toxicological impact.

J. Bouwstra, T. Smijs, 2010, Journal of biomedical nanotechnology.

Phase behavior of skin lipid mixtures: the effect of cholesterol on lipid organization.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2015, Soft matter.

Structural investigations of human stratum corneum by small-angle X-ray scattering.

J. Bouwstra, G. Gooris, W. Bras, 1991, The Journal of investigative dermatology.

Small is beautiful: N-trimethyl chitosan-ovalbumin conjugates for microneedle-based transcutaneous immunisation.

Wim Jiskoot, W. Jiskoot, J. Bouwstra, 2011, Vaccine.

Hyaluronan molecular weight: effects on dissolution time of dissolving microneedles in the skin and on immunogenicity of antigen.

J. Bouwstra, C. O’Mahony, G. Kersten, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Dissolving Microneedle Patches for Dermal Vaccination

J. Bouwstra, G. Kersten, M. Leone, 2017, Pharmaceutical Research.

Fluorescent nanoparticle adhesion assay: a novel method for surface pKa determination of self-assembled monolayers on silicon surfaces.

Koen van der Maaden, Joke Bouwstra, Alexander Kros, 2012, Langmuir : the ACS journal of surfaces and colloids.

Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines.

W. Jiskoot, T. Ottenhoff, J. Bouwstra, 2011, Vaccine.

Niosomes as a novel peroral vaccine delivery system.

H. Junginger, J. Bouwstra, C. Rentel, 1999, International journal of pharmaceutics.

In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers

Claus-Michael Lehr, Hans E. Junginger, Etienne Schacht, 1992 .

Characterization of Stratum Corneum Molecular Dynamics by Natural-Abundance 13C Solid-State NMR

D. Topgaard, A. Nowacka, J. Bouwstra, 2013, PloS one.

Bioadhesion by Means of Specific Binding of Tomato Lectin

Claus-Michael Lehr, Hans E. Junginger, H. Junginger, 1992, Pharmaceutical Research.

Interactions of elastic and rigid vesicles with human skin in vitro: electron microscopy and two-photon excitation microscopy.

H. Junginger, J. Bouwstra, B. A. van den Bergh, 1999, Biochimica et biophysica acta.

3D skin models for 3R research: The potential of 3D reconstructed skin models to study skin barrier function

J. Bouwstra, J. Brandner, H. Niehues, 2018, Experimental dermatology.

Barrier Function in Reconstructed Epidermis and Its Resemblance to Native Human Skin

M. Mommaas, J. Bouwstra, M. Ponec, 2001, Skin Pharmacology and Physiology.

Safety Aspects of Non‐ionic Surfactant Vesicles: A Toxicity Study Related to the Physicochemical Characteristics of Non‐ionic Surfactants

H. Junginger, J. Bouwstra, M. Ponec, 1992, The Journal of pharmacy and pharmacology.

The influence of the molar ratio of cholesteryl hemisuccinate/dipalmitoylphosphatidylcholine on 'liposome' formation after lipid film hydration.

J. Bouwstra, G. Gooris, D. Crommelin, 1992, Chemistry and physics of lipids.

The pharmacokinetics and pharmacological effect of (S)-5-OH-DPAT following controlled delivery with transdermal iontophoresis.

B. Westerink, M. Danhof, R. Vreeken, 2011, Journal of pharmaceutical sciences.

Transdermal iontophoretic delivery of a novel series of dopamine agonists in vitro: physicochemical considerations

M. Danhof, J. Bouwstra, O. Ackaert, 2010, The Journal of pharmacy and pharmacology.

The in vitro and in vivo evaluation of new synthesized prodrugs of 5-OH-DPAT for iontophoretic delivery.

B. Westerink, M. Danhof, J. Bouwstra, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Transdermal iontophoresis of dopaminergic (pro) drugs : from formulation to in vivo application

M. Danhof, J. Bouwstra, O. Ackaert, 2005 .

Self‐assembly of thiolated versus non‐thiolated peptide amphiphiles

A. Boyle, J. Bouwstra, G. Gooris, 2021, Peptide Science.

Chapter 1 Transcutaneous immunization : A general introduction

Wim, J. Bouwstra, G. Kersten, 2010 .

Visualization studies of human skin in vitro/in vivo under the influence of an electrical field.

J. Bouwstra, H. Koerten, A. D. de Graaff, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Raman and AFM-IR chemical imaging of stratum corneum model membranes

M. Lafleur, J. Bouwstra, G. Gooris, 2020, Canadian Journal of Chemistry.

Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formation

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, Scientific Reports.

Electrically-assisted skin delivery of pergolide in vitro: effect of pH, donor concentration and surfactants

J. Bouwstra, D. Fatouros, A. Nugroho, 2006 .

Transdermal iontophoretic delivery of apomorphine in patients improved by surfactant formulation pretreatment.

M. Danhof, T. van Laar, J. Bouwstra, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Pretreatment with a Water-Based Surfactant Formulation Affects Transdermal Iontophoretic Delivery of R-Apomorphine in Vitro

M. Danhof, J. Bouwstra, P. Frederik, 2003, Pharmaceutical Research.

Effect of Elastic Liquid-State Vesicle on Apomorphine Iontophoresis Transport Through Human Skin In Vitro

M. Danhof, J. Bouwstra, G. Li, 2001, Pharmaceutical Research.

Iontophoretic R-apomorphine delivery in combination with surfactant pretreatment: in vitro validation studies.

M. Danhof, J. Bouwstra, G. Li, 2003, International journal of pharmaceutics.

In vitro iontophoresis of R-apomorphine across human stratum corneum. Structure-transport relationship of penetration enhancement.

M. Danhof, J. Bouwstra, G. Li, 2002, Journal of controlled release : official journal of the Controlled Release Society.

On-line diffusion profile of a lipophilic model dye in different depths of a hair follicle in human scalp skin.

G. Lamers, J. Bouwstra, Y. Grams, 2005, The Journal of investigative dermatology.

The in£uence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum

J. Bouwstra, G. Gooris, H. Koerten, 2001 .

Thermodynamic and structural aspects of the skin barrier

J. Brussee, J. Bouwstra, G. Gooris, 1991 .

Visualization studies of the mucoadhesive interface

H. Junginger, J. Bouwstra, J. Onderwater, 1992 .

Unravelling effects of relative humidity on lipid barrier formation in human skin equivalents

J. Bouwstra, G. Gooris, J. Aerts, 2019, Archives of Dermatological Research.

Mechanistic studies of the transdermal iontophoretic delivery of 5-OH-DPAT in vitro.

M. Danhof, J. Bouwstra, O. Ackaert, 2010, Journal of pharmaceutical sciences.

Iontophoretic Delivery of Apomorphine In Vitro: Physicochemic Considerations

M. Danhof, J. Bouwstra, G. Li, 2001, Pharmaceutical Research.

Compartmental Modeling of Transdermal Iontophoretic Transport II: In Vivo Model Derivation and Application

M. Danhof, J. Bouwstra, A. Nugroho, 2004, Pharmaceutical Research.

Human skin equivalents: impaired barrier function in relation to the lipid and protein properties of the stratum corneum.

J. Bouwstra, A. El Ghalbzouri, Richard W J Helder, 2021, Advanced drug delivery reviews.

Characterization of human skin equivalents developed at body's core and surface temperatures

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, Journal of tissue engineering and regenerative medicine.

Recapitulation of Native Dermal Tissue in a Full-Thickness Human Skin Model Using Human Collagens.

J. Bouwstra, A. El Ghalbzouri, M. Rietveld, 2017, Tissue engineering. Part A.

Increased presence of monounsaturated fatty acids in the stratum corneum of human skin equivalents.

R. Vreeken, J. Bouwstra, A. Mulder, 2013, The Journal of investigative dermatology.

Characterization and skin permeation of ketoprofen-loaded vesicular systems.

J. Bouwstra, G. Gooris, T. Uchino, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

A combined approach of vesicle formulations and microneedle arrays for transcutaneous immunization against hepatitis B virus.

W. Jiskoot, J. Bouwstra, Jean‐Pierre Amorij, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The in vivo and in vitro interactions of elastic and rigid vesicles with human skin.

J. Bouwstra, A. D. de Graaff, H. Groenink, 2002, Biochimica et biophysica acta.

Intestinal transit of bioadhesive microspheres in an in situ loop in the rat—A comparative study with copolymers and blends based on poly(acrylic acid)

H. Junginger, J. Bouwstra, C. Lehr, 1990 .

Antigen-adjuvant nanoconjugates for nasal vaccination: an improvement over the use of nanoparticles?

W. Jiskoot, J. Bouwstra, C. Löwik, 2010, Molecular pharmaceutics.

In vivo visualization of microneedle conduits in human skin using laser scanning microscopy

Martina C. Meinke, Juergen Lademann, J. Bouwstra, 2010 .

Transport of peptide and protein drugs across biological membranes

H. Junginger, J. Bouwstra, H. Boddé, 1990, European Journal of Drug Metabolism and Pharmacokinetics.

Synthetic hydrogels as drug delivery systems

H. Junginger, J. Bouwstra, H. Boddé, 2005, Pharmaceutisch Weekblad.

Interactions between liposomes and human stratum corneum studied by freeze-substitution electron microscopy

J. Bouwstra, B. Bergh, I. D. Vries, 1998 .

Quantitative analysis of ceramides using a novel lipidomics approach with three dimensional response modelling.

R. Vreeken, J. Bouwstra, S. Absalah, 2016, Biochimica et biophysica acta.

Ceramides in the skin lipid membranes: length matters.

J. Bouwstra, G. Gooris, P. Slepička, 2013, Langmuir : the ACS journal of surfaces and colloids.

Efficient induction of immune responses through intradermal vaccination with N-trimethyl chitosan containing antigen formulations.

Elly van Riet, Gideon F A Kersten, Wim Jiskoot, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Adjuvant effect of cationic liposomes and CpG depends on administration route.

W. Jiskoot, J. Bouwstra, B. Slütter, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination.

W. Hennink, W. Jiskoot, J. Bouwstra, 2011, Journal of controlled release : official journal of the Controlled Release Society.

TRANSDERM AL IONTOPHORESIS OF ROTIGOTINE : INFLUENCE OF CONCENTRATION , TEM PERATURE AND CURRENT DENSITY IN HUM AN SKIN IN VITRO

M. Danhof, J. Bouwstra, A. Nugroho, 2005 .

Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro.

M. Danhof, J. Bouwstra, A. Nugroho, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Lipophilic and hydrophilic moisturizers show different actions on human skin as revealed by cryo scanning electron microscopy

J. Bouwstra, G. Gooris, J. Wiechers, 2007, Experimental dermatology.

The lipid organisation in the skin barrier.

J. Bouwstra, G. Gooris, M. Ponec, 2000, Acta dermato-venereologica. Supplementum.

The influence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum.

J. Bouwstra, G. Gooris, H. Koerten, 2001, Biochimica et biophysica acta.

Structure of human stratum corneum as a function of temperature and hydration a wide-angle X-ray diffraction study

J. Bouwstra, G. Gooris, W. Bras, 1992 .

pH, cholesterol sulfate, and fatty acids affect the stratum corneum lipid organization.

J. Bouwstra, G. Gooris, A. Weerheim, 1998, The journal of investigative dermatology. Symposium proceedings.

Lipid organization in pig stratum corneum.

D. Downing, J. Bouwstra, G. Gooris, 1995, Journal of lipid research.

A Surface Energy Analysis of Mucoadhesion: Contact Angle Measurements on Polycarbophil and Pig Intestinal Mucosa in Physiologically Relevant Fluids

H. Junginger, J. Bouwstra, H. Boddé, 2004, Pharmaceutical Research.

A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases.

J. Bouwstra, T. Smijs, S. Pavel, 2007, The Journal of antimicrobial chemotherapy.

Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment.

J. Bouwstra, T. Smijs, S. Pavel, 2007, The Journal of antimicrobial chemotherapy.

Morphological changes of the dermatophyte Trichophyton rubrum after photodynamic treatment: a scanning electron microscopy study.

J. Bouwstra, J. Onderwater, H. Koerten, 2008, Medical mycology.

Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Formation in Human Skin Equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, International journal of molecular sciences.

An ex vivo human skin model for studying skin barrier repair

J. Bouwstra, Arnout Mieremet, M. Danso, 2015, Experimental dermatology.

A theoretical compartment model for antigen kinetics in the skin.

C. Oomens, D. Bader, J. Bouwstra, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Liposomes and niosomes as topical drug carriers: dermal and transdermal drug delivery

J. Bouwstra, H. Schreier, 1994 .

Wide‐angle X‐ray Diffraction of Human Stratum Corneum: Effects of Hydration and Terpene Enhancer Treatment

J. Bouwstra, B. W. Barry, P. Cornwell, 1994, The Journal of pharmacy and pharmacology.

The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C.

J. Bouwstra, G. Gooris, A. Weerheim, 1997, The Journal of investigative dermatology.

On-Line Visualization of Dye Diffusion in Fresh Unfixed Human Skin

J. Bouwstra, Y. Grams, L. Whitehead, 2004, Pharmaceutical Research.

Hypercholesterolemia in young adult APOE-/- mice alters epidermal lipid composition and impairs barrier function.

J. Bouwstra, G. Gooris, M. Hoekstra, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Combined chemical and electrical enhancement modulates stratum corneum structure.

J. Bouwstra, A. D. de Graaff, A. V. van Aelst, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Transdermal iontophoresis of the dopamine agonist 5-OH-DPAT in human skin in vitro.

H. Wikström, M. Danhof, J. Bouwstra, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Chemical Modifications of Gold Surfaces with Basic Groups and a Fluorescent Nanoparticle Adhesion Assay To Determine Their Surface p Ka.

W. Jiskoot, J. Bouwstra, K. van der Maaden, 2019, Langmuir : the ACS journal of surfaces and colloids.

Diffusion profile of macromolecules within and between human skin layers for (trans)dermal drug delivery.

C. Oomens, F. Baaijens, D. Bader, 2015, Journal of the mechanical behavior of biomedical materials.

In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling[S]

J. Bouwstra, J. Aerts, H. Overkleeft, 2017, Journal of Lipid Research.

Hyperalphalipoproteinemic scavenger receptor BI knockout mice exhibit a disrupted epidermal lipid barrier.

J. Bouwstra, G. Gooris, M. Hoekstra, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

The effects of LXR agonist T0901317 and LXR antagonist GSK2033 on morphogenesis and lipid properties in full thickness skin models.

J. Bouwstra, A. El Ghalbzouri, W. Boiten, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Multitargeted Approach for the Optimization of Morphogenesis and Barrier Formation in Human Skin Equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2021, International journal of molecular sciences.

Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities.

J. Bouwstra, A. Hovnanian, J. Aerts, 2020, Journal of lipid research.

Physicochemical characterization of drug-loaded rigid and elastic vesicles.

J. Bouwstra, G. Gooris, T. Uchino, 2011, International journal of pharmaceutics.

Evaluation of the high-pressure extrusion technique as a method for sizing plasmid DNA-containing cationic liposomes

C. Melief, W. Jiskoot, T. Ottenhoff, 2011, Journal of liposome research.

Diverse regulation of claudin-1 and claudin-4 in atopic dermatitis.

H. Hennies, J. Bouwstra, E. Peters, 2015, The American journal of pathology.

Small angle X-ray scattering: possibilities and limitations in characterization of vesicles.

J. Bouwstra, G. Gooris, W. Bras, 1993, Chemistry and physics of lipids.

Phytosphingosine ceramide mainly localizes in the central layer of the unique lamellar phase of skin lipid model systems

J. Bouwstra, C. Beddoes, R. Dalgliesh, 2022, Journal of lipid research.

The importance of ceramide headgroup for lipid localisation in skin lipid models.

D. Barlow, M. Malfois, J. Bouwstra, 2022, Biochimica et biophysica acta. Biomembranes.

Using molecular simulation to understand the skin barrier

T. C. Moore, C. Iacovella, J. Bouwstra, 2022, Progress in lipid research.

Preparation and characterization of diphtheria toxoid-loaded elastic vesicles for transcutaneous immunization

W. Jiskoot, J. Bouwstra, M. Bivas-Benita, 2008, Journal of drug targeting.

Diphtheria toxoid dissolving microneedle vaccination: adjuvant screening and effect of repeated-fractional dose administration.

J. Bouwstra, C. O’Mahony, G. Kersten, 2020, International journal of pharmaceutics.

Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle.

J. Bouwstra, Y. Grams, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Engineering of an automated nano-droplet dispensing system for fabrication of antigen-loaded dissolving microneedle arrays.

W. Jiskoot, J. Bouwstra, C. O’Mahony, 2021, International journal of pharmaceutics.

Shedding light on the effects of 1,25-dihydroxyvitamin D3 on epidermal lipid barrier formation in three-dimensional human skin equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Monounsaturated fatty acids reduce the barrier of stratum corneum lipid membranes by enhancing the formation of a hexagonal lateral packing.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2014, Langmuir : the ACS journal of surfaces and colloids.

Permeability and lipid organization of a novel psoriasis stratum corneum substitute.

J. Bouwstra, Line Hollesen Basse, D. Groen, 2013, International journal of pharmaceutics.

Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I).

J. Bouwstra, G. Gooris, Diógenes de Sousa Neto, 2011, Chemistry and physics of lipids.

Long periodicity phase in extracted lipids of vernix caseosa obtained with equilibration at physiological temperature.

J. Bouwstra, G. Gooris, M. Ponec, 2009, Chemistry and physics of lipids.

New insights into ultrastructure, lipid composition and organization of vernix caseosa.

J. Bouwstra, A. Weerheim, M. Ponec, 2006, The Journal of investigative dermatology.

Structure of Stratum Corneum Lipid Layers and Interactions with Lipid Liposomes

J. Bouwstra, 2001 .

TOPICAL APPLICATION OF DRUGS: MECHANISMS INVOLVED IN CHEMICAL ENHANCEMENT

J. Bouwstra, B. A. van den Bergh, M. Suhonen, 2001, Journal of receptor and signal transduction research.

The use of vibratome sections for the ruthenium tetroxide protocol: a key for optimal visualization of epidermal lipid bilayers of the entire human stratum corneum in transmission electron microscopy

J. Bouwstra, H. Koerten, A. Mulder, 1996, Journal of microscopy.

Visualization and electron diffraction on cryosections of stratum corneum: a utopia?

J. Bouwstra, J. Onderwater, H. Koerten, 1996 .

Interactions of external lipids (lipid vesicles) with the skin

J. Bouwstra, J. Lasch, 1995 .

An X-ray diffraction study of some model stratum corneum lipids containing Azone and dodecyl-L-pyroglutamate

J. Bouwstra, Geoffrey Lee, F. Schueckler, 1993 .

Stratum corneum lipid composition and structure in cultured skin substitutes is restored to normal after grafting onto athymic mice.

S. Boyce, J. Bouwstra, A. Weerheim, 1998, The journal of investigative dermatology. Symposium proceedings.

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.

J. Bouwstra, G. Gooris, A. Weerheim, 1995, Journal of lipid research.

The lipid and protein structure of mouse stratum corneum: a wide and small angle diffraction study.

J. Bouwstra, G. Gooris, W. Bras, 1994, Biochimica et biophysica acta.

Universal Applicator for Digitally-Controlled Pressing Force and Impact Velocity Insertion of Microneedles into Skin

J. Bouwstra, C. O’Mahony, G. Kersten, 2018, Pharmaceutics.

Transdermal iontophoresis of timolol across human stratum corneum: effect of temperature and vehicle formulation

J. Bouwstra, D. Fatouros, 2004 .

One Peptide for Them All: Gold Nanoparticles of Different Sizes Are Stabilized by a Common Peptide Amphiphile

A. Boyle, J. Bouwstra, G. Gooris, 2020, ACS nano.

Chapter 7

W. Jiskoot, J. Bouwstra, B. Slütter, 2009 .

Hyaluronan‐based dissolving microneedles with high antigen content for intradermal vaccination: Formulation, physicochemical characterization and immunogenicity assessment

W. Jiskoot, J. Bouwstra, C. O’Mahony, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Glucosylated cholesterol in skin: synthetic role of extracellular glucocerebrosidase.

J. Bouwstra, A. Hovnanian, Johannes M F G Aerts, 2020, Clinica chimica acta; international journal of clinical chemistry.

Chemical modifications of silicon surfaces for the generation of a tunable surface isoelectric point.

W. Jiskoot, J. Bouwstra, K. van der Maaden, 2014, Langmuir : the ACS journal of surfaces and colloids.

Chemical modifications of silicon surfaces for the generation of a tunable isoelectric point

W. Jiskoot, J. Bouwstra, K. V. D. Maaden, 2014 .

Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting Stearoyl-CoA Desaturase-1.

J. Bouwstra, A. El Ghalbzouri, W. Boiten, 2021, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Enhanced permeability of freeze-dried liposomal bilayers upon rehydration.

J. Bouwstra, D. Crommelin, E. C. van Winden, 1997, Cryobiology.

Preparation and Characterization of Nonionic Surfactant Vesicles

H. Junginger, J. Bouwstra, D. A. V. Hal, 1996 .

Interactions Between non-ionic Surfactant Vesicles and human stratum corneum in vitro.

H. Junginger, J. Bouwstra, H. Boddé, 1995 .

Niosomes for oral delivery of peptide drugs

H. Junginger, J. Bouwstra, C. Lehr, 1992 .

Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice.

J. Bouwstra, F. Verbaan, M. Bivas-Benita, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Nature versus nurture: does human skin maintain its stratum corneum lipid properties in vitro?

J. Bouwstra, A. Mulder, A. El Ghalbzouri, 2012, Experimental dermatology.

Culture of reconstructed epidermis in a defined medium at 33° C shows a delayed epidermal maturation, prolonged lifespan and improved stratum corneum

J. Bouwstra, M. Ponec, S. Gibbs, 1997, Archives of Dermatological Research.

Interactions of dipalmitoylphosphatidylcholine with ceramide-based mixtures.

J. Bouwstra, G. Gooris, A. Kros, 2018, Biochimica et biophysica acta. Biomembranes.

Effect of N-alkyl-azocycloheptan-2-ones including azone on the thermal behaviour of human stratum corneum

J. Brussee, J. Bouwstra, H. Boddé, 1989 .

Repeated fractional intradermal dosing of an inactivated polio vaccine by a single hollow microneedle leads to superior immune responses.

Koen van der Maaden, Joke Bouwstra, Gideon Kersten, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Hollow microneedle‐mediated intradermal delivery of model vaccine antigen‐loaded PLGA nanoparticles elicits protective T cell‐mediated immunity to an intracellular bacterium

J. Bouwstra, F. Broere, A. Sijts, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Effect of electrolyte on the phase behavior and emulsion stability in the system didodecyldimethylammonium bromide (DDAB)/dodecane/water

J. Bouwstra, G. Gooris, J. Sjöblom, 1992 .

Skin Hydration - A Key Determinant in Topical Absorption

Roberts, J. Bouwstra, F. Pirot, 2008 .

Compromising human skin in vivo and ex vivo to study skin barrier repair.

A. Lavrijsen, J. Bouwstra, S. Absalah, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements.

P. Wertz, H. Junginger, J. Bouwstra, 2001, International journal of pharmaceutics.

Development of PLGA nanoparticle loaded dissolving microneedles and comparison with hollow microneedles in intradermal vaccine delivery

W. Jiskoot, J. Bouwstra, C. O’Mahony, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro

A. Lavrijsen, J. Bouwstra, A. Mulder, 2015, Cell and Tissue Research.

Impact-Insertion Applicator Improves Reliability of Skin Penetration by Solid Microneedle Arrays

W. Jiskoot, J. Bouwstra, K. V. D. Maaden, 2014, The AAPS Journal.

Thermal analysis of water in p(HEMA) hydrogels.

H. Junginger, J. Bouwstra, W. Roorda, 1988, Biomaterials.

Skin Penetration and Mechanisms of Action in the Delivery of the D2-Agonist Rotigotine from Surfactant-Based Elastic Vesicle Formulations

J. Bouwstra, P. Honeywell-Nguyen, Sonia Arenja, 2003, Pharmaceutical Research.

AFM Study of Lipid Monolayers: III. Phase Behavior of Ceramides, Cholesterol and Fatty Acids

J. Bouwstra, E. Sparr, K. Ekelund, 2001 .

Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems.

Yvonne Perrie, Wim Jiskoot, W. Jiskoot, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Lipid bilayer‐coated mesoporous silica nanoparticles carrying bovine hemoglobin towards an erythrocyte mimic

J. Bouwstra, A. Kros, J. Tu, 2018, International journal of pharmaceutics.

Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

Koen van der Maaden, Alexander Kros, Wim Jiskoot, 2017, Pharmaceutical Research.

Structure of the skin barrier and its modulation by vesicular formulations.

J. Bouwstra, G. Gooris, M. Ponec, 2003, Progress in lipid research.

The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes.

J. Bouwstra, G. Gooris, K. Bito, 2014, Biochimica et biophysica acta.

Water distribution and related morphology in human stratum corneum at different hydration levels.

Johann W Wiechers, J. Bouwstra, G. Gooris, 2003, The Journal of investigative dermatology.

Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range.

J. Bouwstra, G. Gooris, M. Ponec, 1999, Journal of lipid research.

Electron diffraction provides new information on human stratum corneum lipid organization studied in relation to depth and temperature.

J. Bouwstra, H. Koerten, G. Pilgram, 1999, The Journal of investigative dermatology.

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery[S]

Thomas Hankemeier, T. Hankemeier, R. Vreeken, 2011, Journal of Lipid Research.

New insights into the stratum corneum lipid organization by X-ray diffraction analysis.

J. Bouwstra, G. Gooris, D. Groen, 2009, Biophysical journal.

The skin barrier in healthy and diseased state.

Maria Ponec, J. Bouwstra, M. Ponec, 2006, Biochimica et biophysica acta.

A Novel in Vitro Percutaneous Penetration Model: Evaluation of Barrier Properties with P-Aminobenzoic Acid and Two of Its Derivatives

J. Bouwstra, M. Ponec, N. Angelova, 2006, Pharmaceutical Research.

Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500221-JLR200

J. Bouwstra, G. Gooris, M. Ponec, 2005, Journal of Lipid Research.

Modelling the stratum corneum lipid organisation with synthetic lipid mixtures: the importance of synthetic ceramide composition.

J. Bouwstra, G. Gooris, M. Ponec, 2004, Biochimica et biophysica acta.

In Vitro Human Skin Barrier Modulation by Fatty Acids: Skin Permeation and Thermal Analysis Studies

H. Junginger, J. Bouwstra, H. Boddé, 2004, Pharmaceutical Research.

TNF-α and Th2 cytokines induce atopic dermatitis-like features on epidermal differentiation proteins and stratum corneum lipids in human skin equivalents.

J. Bouwstra, A. Mulder, Joke A Bouwstra, 2014, The Journal of investigative dermatology.

The important role of stratum corneum lipids for the cutaneous barrier function.

J. Bouwstra, G. Gooris, J. van Smeden, 2014, Biochimica et biophysica acta.

Role of ceramide 1 in the molecular organization of the stratum corneum lipids.

A. IJzerman, J. Bouwstra, G. Gooris, 1998, Journal of lipid research.

Vesicles as a tool for transdermal and dermal delivery.

J. Bouwstra, Joke A Bouwstra, P Loan Honeywell-Nguyen, 2005, Drug discovery today. Technologies.

The susceptibility of trichophyton rubrum to photodynamic treatment

R. Willemze, J. Bouwstra, S. Pavel, 2005 .

Preclinical Studies with 5,10,15‐Tris(4‐Methylpyridinium)‐20‐Phenyl‐[21H,23H]‐Porphine Trichloride for the Photodynamic Treatment of Superficial Mycoses Caused by Trichophyton rubrum

J. Bouwstra, T. Smijs, S. Pavel, 2009, Photochemistry and photobiology.

Development of an optimal protocol for the ultrastructural examination of skin by transmission electron microscopy

H. Junginger, J. Bouwstra, H. Boddé, 1997, Journal of microscopy.

Dry skin management: practical approach in light of latest research on skin structure and function

E. Berardesca, L. Misery, J. Bouwstra, 2019, The Journal of dermatological treatment.

In vivo assessment of safety of microneedle arrays in human skin.

J. Bouwstra, Suzanne M Bal, Joke A Bouwstra, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Estradiol Permeation from Nonionic Surfactant Vesicles Through Human Stratum Corneum in Vitro

H. Junginger, J. Bouwstra, H. Boddé, 1994, Pharmaceutical Research.

Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations.

A. Urtti, J. Bouwstra, T. Suhonen, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin

J. Bouwstra, G. Gooris, T. Berkers, 2018, Pharmaceutical Research.

Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.

J. Bouwstra, J. van Smeden, 2016, Current problems in dermatology.

Skin barrier disruption by acetone: observations in a hairless mouse skin model

W. Hennink, J. Bouwstra, M. Ponec, 2009, Archives of Dermatological Research.

Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis.

J. Bouwstra, H. Koerten, H. Koerten, 2001, The Journal of investigative dermatology.

Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies.

J. Bouwstra, G. Gooris, M. Ponec, 2006, Biochimica et biophysica acta.

Compartmental Modeling of Transdermal Iontophoretic Transport: I. In Vitro Model Derivation and Application

M. Danhof, J. Bouwstra, O. Della Pasqua, 2004, Pharmaceutical Research.

Elasticity of vesicles affects hairless mouse skin structure and permeability.

P. Wertz, H. Junginger, J. Bouwstra, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Diffusion of estradiol from non-ionic surfactant vesicles through human stratum corneum in vitro

H. Junginger, J. Bouwstra, D. A. V. Hal, 1996 .

LARGE DISK-SHAPED STRUCTURES (DISCOMES) IN NONIONIC SURFACTANT VESICLE TO MICELLE TRANSITIONS

J. Bouwstra, I. Uchegbu, A. Florence, 1992 .

Niosomes: A study of structure, stability, drug release and toxicological aspects

H. Junginger, J. Bouwstra, H. Hofland, 1990 .

Application of vesicles to rat skin in vivo: a confocal laser scanning microscopy study.

H E Junginger, H. Junginger, J. Bouwstra, 1998, Journal of controlled release : official journal of the Controlled Release Society.

The in vitro transport of pergolide from surfactant-based elastic vesicles through human skin: a suggested mechanism of action.

J. Bouwstra, P. Honeywell-Nguyen, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Preparation and Characterization of Nonionic Surfactant Vesicles

H. Junginger, J. Bouwstra, D. A. V. Hal, 1996 .

Nonionic Surfactant Vesicles: A Study of Vesicle Formation, Characterization, and Stability

H. Junginger, J. Bouwstra, G. Gooris, 1993 .

Interactions of non-ionic surfactant vesicles with cultured keratinocytes and human skin in vitro: a survey of toxicological aspects and ultrastructural changes in stratum corneum

H. Junginger, J. Bouwstra, H. Boddé, 1991 .

Liposomes and niosomes : interactions with human skin

H. Junginger, J. Bouwstra, H. Hofland, 1991 .

Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.

Sangeeta Khare, Carsten Kneuer, Uwe Marx, 2015, ALTEX.

Temperature-induced changes in structural and physicochemical properties of vernix caseosa.

W. Hennink, J. Bouwstra, G. Gooris, 2008, The Journal of investigative dermatology.

Intercellular skin barrier lipid composition and organization in Netherton syndrome patients.

R. Vreeken, J. Bouwstra, A. Hovnanian, 2014, The Journal of investigative dermatology.

Thermal Analysis Studies on Human Skin and Skin Barrier Modulation by Fatty Acids and Propylene Glycol

H. Junginger, J. Bouwstra, H. Boddé, 1999 .

Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method.

J. Bouwstra, F. Verbaan, R. Luttge, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Transdermal Macromolecular Delivery: Real-Time Visualisation of Iontophoretic and Chemically Enhanced Transport Using Two-Photon Excitation Microscopy

W. J. Irwin, A. Naik, J. Bouwstra, 2000, Pharmaceutical Research.

Transdermal Delivery of Pergolide from Surfactant-Based Elastic and Rigid Vesicles: Characterization and in Vitro Transport Studies

H. Junginger, J. Bouwstra, P. Bomans, 2002, Pharmaceutical Research.

Interactions between liposomes and human stratum corneum in vitro: freeze fracture electron microscopical visualization and small angle X‐ray scattering studies

H. Junginger, J. Bouwstra, H. Boddé, 1995, The British journal of dermatology.

The influence of alkyl-azones on the ordering of the lamellae in human stratum corneum

J. Brussee, J. Bouwstra, G. Gooris, 1992 .

Transcutaneous Immunization Studies in Mice Using Diphtheria Toxoid-Loaded Vesicle Formulations and a Microneedle Array

W. Jiskoot, J. Bouwstra, G. Kersten, 2010, Pharmaceutical Research.

Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study.

H. Junginger, J. Bouwstra, M. E. van Kuijk-Meuwissen, 1998, Biochimica et biophysica acta.

A surface energy analysis of mucoadhesion II. Prediction of mucoadhesive performance by spreading coefficients

H. Junginger, J. Bouwstra, H. Boddé, 1993 .

Human skin equivalents are an excellent tool to study the effect of moisturizers on the water distribution in the stratum corneum

J. Bouwstra, M. Ponec, H. Groenink, 2012, International journal of cosmetic science.

Water distribution and natural moisturizer factor content in human skin equivalents are regulated by environmental relative humidity.

J. Bouwstra, M. Ponec, S. Romeijn, 2008, The Journal of investigative dermatology.

Microneedle-based drug and vaccine delivery via nanoporous microneedle arrays

Regina Luttge, Koen van der Maaden, Pieter Jan Vos, 2015, Drug Delivery and Translational Research.

Electroperturbation of the human skin barrier in vitro: II. Effects on stratum corneum lipid ordering and ultrastructure

H. Junginger, J. Bouwstra, G. Gooris, 1997, Microscopy research and technique.

Microneedle technologies for (trans)dermal drug and vaccine delivery.

Koen van der Maaden, Joke Bouwstra, Wim Jiskoot, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Diphtheria toxoid and N-trimethyl chitosan layer-by-layer coated pH-sensitive microneedles induce potent immune responses upon dermal vaccination in mice.

C. Oomens, W. Jiskoot, J. Bouwstra, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

W. Jiskoot, J. Bouwstra, P. Bomans, 2017, Pharmaceutical Research.

Monitoring the penetration process of single microneedles with varying tip diameters.

F P T Baaijens, D L Bader, C W J Oomens, 2014, Journal of the mechanical behavior of biomedical materials.

IgG-loaded hyaluronan-based dissolving microneedles for intradermal protein delivery.

Wim Jiskoot, W. Jiskoot, J. Bouwstra, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles

Abraham J. Koster, Roman I. Koning, Alexander Kros, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Dissolving Microneedle Patches for Dermal Vaccination

J. Bouwstra, G. Kersten, M. Leone, 2017, Pharmaceutical Research.

Influence of microneedle shape on the transport of a fluorescent dye into human skin in vivo.

Jürgen Lademann, Martina C Meinke, Ekkehart Dietz, 2010, Journal of controlled release : official journal of the Controlled Release Society.

The skin barrier, a well-organized membrane

J. Bouwstra, Joke A. Bouwstra, 1997 .

Novel Hollow Microneedle Technology for Depth-Controlled Microinjection-Mediated Dermal Vaccination: A Study with Polio Vaccine in Rats

Thomas Hankemeier, Joke Bouwstra, Gideon Kersten, 2014, Pharmaceutical Research.

STATIC and TIME‐RESOLVED FLUORESCENCE OF AN AMPHIPHILIC FLAVIN IN AEROSOL OT REVERSED MICELLES

J. Bouwstra, A. Visser, A. Hoek, 1987 .

Determination of Depth-Dependent Intradermal Immunogenicity of Adjuvanted Inactivated Polio Vaccine Delivered by Microinjections via Hollow Microneedles

Joke Bouwstra, Gideon Kersten, Cees Oomens, 2016, Pharmaceutical Research.

Predicting the optimal geometry of microneedles and their array for dermal vaccination using a computational model

C. Oomens, D. Bader, J. Bouwstra, 2016, Computer methods in biomechanics and biomedical engineering.

Parameter optimization toward optimal microneedle-based dermal vaccination.

W. Jiskoot, J. Bouwstra, S. Romeijn, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Ovalbumin-coated pH-sensitive microneedle arrays effectively induce ovalbumin-specific antibody and T-cell responses in mice.

W. Jiskoot, J. Bouwstra, F. Ossendorp, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Impact-Insertion Applicator Improves Reliability of Skin Penetration by Solid Microneedle Arrays

W. Jiskoot, J. Bouwstra, K. van der Maaden, 2014, The AAPS Journal.

Advances in transcutaneous vaccine delivery: do all ways lead to Rome?

Elly van Riet, Wim Jiskoot, W. Jiskoot, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Assembled microneedle arrays enhance the transport of compounds varying over a large range of molecular weight across human dermatomed skin.

J. Bouwstra, F. Verbaan, S. Bal, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Comprehensive evaluation of microneedle‐based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial

W. Jiskoot, J. Bouwstra, M. D. de Kam, 2021, British journal of clinical pharmacology.

Modes of action of terpene penetration enhancers in human skin; Differential scanning calorimetry, small-angle X-ray diffraction and enhancer uptake studies

J. Bouwstra, G. Gooris, B. W. Barry, 1996 .

Structure of fully hydrated human stratum corneum: a freeze-fracture electron microscopy study.

H. Junginger, J. Bouwstra, F. Spies, 1996, The Journal of investigative dermatology.

Iontophoretic Enhancement of Timolol across Human Dermatomed Skin In Vitro

J. Bouwstra, D. Fatouros, 2004, Journal of drug targeting.

Investigating the barrier function of skin lipid models with varying compositions.

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Lipid and ultrastructural characterization of reconstructed skin models.

M. Mommaas, J. Bouwstra, A. Weerheim, 2000, International journal of pharmaceutics.

Glucocerebrosidase: Functions in and Beyond the Lysosome

J. Bouwstra, J. Aerts, J. van Smeden, 2020, Journal of clinical medicine.

New insight into phase behavior and permeability of skin lipid models based on sphingosine and phytosphingosine ceramides.

J. Bouwstra, G. Gooris, C. Beddoes, 2019, Biochimica et biophysica acta. Biomembranes.

Synthesis and characterization of hyperbranched polyglycerol hydrogels.

W. Hennink, J. Bouwstra, R. Rissmann, 2006, Biomaterials.

Very Long Chain Lipids Favor the Formation of a Homogeneous Phase in Stratum Corneum Model Membranes.

M. Lafleur, J. Bouwstra, A. P. Ramos, 2020, Langmuir : the ACS journal of surfaces and colloids.

Lipid Organization of the Skin Barrier

J. Bouwstra, 2016 .

Infrared spectroscopy studies of mixtures prepared with synthetic ceramides varying in head group architecture: coexistence of liquid and crystalline phases.

J. Bouwstra, G. Gooris, M. Janssens, 2009, Biochimica et biophysica acta.

Acylceramide head group architecture affects lipid organization in synthetic ceramide mixtures.

J. Bouwstra, G. Gooris, M. Ponec, 2004, The Journal of investigative dermatology.

Novel lipid mixtures based on synthetic ceramides reproduce the unique stratum corneum lipid organization Published, JLR Papers in Press, February 16, 2004. DOI 10.1194/jlr.M300484-JLR200

J. Bouwstra, G. Gooris, M. Ponec, 2004, Journal of Lipid Research.

The phase behaviour of skin lipid mixtures based on synthetic ceramides.

J. Bouwstra, G. Gooris, M. Ponec, 2003, Chemistry and physics of lipids.

Does the single gel phase exist in stratum corneum?

J. Bouwstra, G. Pilgram, M. Ponec, 2002, The Journal of investigative dermatology.

Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction.

J. Bouwstra, G. Oostergetel, H. Koerten, 1998, Journal of lipid research.

FTIR studies show lipophilic moisturizers to interact with stratum corneum lipids, rendering the more densely packed.

J. Bouwstra, G. Gooris, J. Caussin, 2008, Biochimica et biophysica acta.

High concentration of the ester-linked ω-hydroxy ceramide increases the permeability in skin lipid model membranes.

J. Bouwstra, C. Beddoes, G. Gooris, 2020, Biochimica et biophysica acta. Biomembranes.

Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum.

J. Bouwstra, G. Gooris, T. Berkers, 2018, Acta dermato-venereologica.

Topically applied fatty acids are elongated before incorporation in the stratum corneum lipid matrix in compromised skin

J. Bouwstra, S. Absalah, T. Berkers, 2017, Experimental dermatology.

Stratum corneum lipid matrix: Location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase.

D. Barlow, J. Bouwstra, G. Gooris, 2016, Biochimica et biophysica acta.

NATURE VS NURTURE: DOES HUMAN SKIN MAINTAIN ITS BARRIER PROPERTIES IN VITRO?

J. Bouwstra, A. Mulder, A. E. Ghalbzouri, 2012 .

Unraveling barrier properties of three different in-house human skin equivalents.

J. Bouwstra, A. Mulder, A. El Ghalbzouri, 2012, Tissue engineering. Part C, Methods.

Disposition of ceramide in model lipid membranes determined by neutron diffraction.

D. Barlow, J. Bouwstra, G. Gooris, 2011, Biophysical journal.

Generation of human skin equivalents under submerged conditions-mimicking the in utero environment.

J. Bouwstra, M. Ponec, Varsha S. Thakoersing, 2010, Tissue engineering. Part A.

Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol, and fatty acids.

J. Bouwstra, G. Gooris, 2007, Biophysical journal.

Stratum corneum model membranes: molecular organization in relation to skin barrier function

J. Bouwstra, D. Groen, 2007 .

Phase behavior of stratum corneum lipid mixtures based on human ceramides: the role of natural and synthetic ceramide 1.

J. Bouwstra, G. Gooris, F. E. Dubbelaar, 2002, The Journal of investigative dermatology.

Effects of the Mucoadhesive Polymer Polycarbophil on the Intestinal Absorption of a Peptide Drug in the Rat

H. Junginger, J. Bouwstra, C. Lehr, 1992, The Journal of pharmacy and pharmacology.

A structural study of the mesophases of two oxyethylene alkyl ether-decane-water systems, a comparison between technical grade C12EO〈7〉 and pure C12EO6

J. Bouwstra, G. Gooris, F. Spies, 1989 .

Cross-Relaxation Effects in Pulsed-Field-Gradient Stimulated-Echo Measurements on Water in a Macromolecular Matrix

H. Junginger, J. Bouwstra, J. Leyte, 1996 .

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

James T. Elder, P. Jansen, J. Bouwstra, 2017, The Journal of investigative dermatology.

Development of a murine model to evaluate the effect of vernix caseosa on skin barrier recovery

Wim E Hennink, Maria Ponec, W. Hennink, 2009, Experimental dermatology.

Antigen Uptake After Intradermal Microinjection Depends on Antigen Nature and Formulation, but Not on Injection Depth

W. Jiskoot, J. Bouwstra, A. Kros, 2021, Frontiers in Allergy.

Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents.

J. Bouwstra, G. Gooris, A. Mulder, 2015, Journal of dermatological science.

Towards tailored vaccine delivery: needs, challenges and perspectives.

W. Hinrichs, W. Jiskoot, J. Bouwstra, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formation

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, Scientific Reports.

Adjuvanted, antigen loaded N-trimethyl chitosan nanoparticles for nasal and intradermal vaccination: adjuvant- and site-dependent immunogenicity in mice.

W. Jiskoot, J. Bouwstra, B. Slütter, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination.

W. Jiskoot, J. Bouwstra, S. Bal, 2011, Vaccine.

Synthesis of methacrylated hyaluronic acid with tailored degree of substitution

W. Hennink, J. Bouwstra, R. Rissmann, 2007 .

Hollow microneedle‐mediated micro‐injections of a liposomal HPV E743–63 synthetic long peptide vaccine for efficient induction of cytotoxic and T‐helper responses

Koen van der Maaden, Joke Bouwstra, Wim Jiskoot, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Efficient Eradication of Established Tumors in Mice with Cationic Liposome-Based Synthetic Long-Peptide Vaccines

W. Jiskoot, J. Bouwstra, F. Ossendorp, 2017, Cancer Immunology Research.

Cationic Liposomes Loaded with a Synthetic Long Peptide and Poly(I:C): a Defined Adjuvanted Vaccine for Induction of Antigen-Specific T Cell Cytotoxicity

W. Jiskoot, J. Bouwstra, F. Ossendorp, 2014, The AAPS Journal.

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.

Ivo Que, Joke Bouwstra, Patrick Augustijns, 2010, Vaccine.

Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities[S]

J. Bouwstra, A. Hovnanian, J. Aerts, 2020, Journal of Lipid Research.

The physico-chemical characterization of poly (2-hydroxyethyl methacrylate-co-methacrylic acid): 1. Effect of PEG 400 on the tacticity and reactivity ratios

H. Junginger, J. Bouwstra, J. Verhoeven, 1989 .

Evidence of hydrocarbon nanodrops in highly ordered stratum corneum model membranes[S]

M. Lafleur, J. Bouwstra, G. Gooris, 2017, Journal of Lipid Research.

The role of ceramide composition in the lipid organisation of the skin barrier.

J. Bouwstra, G. Gooris, A. Weerheim, 1999, Biochimica et biophysica acta.

A model membrane approach to the epidermal permeability barrier: an X-ray diffraction study.

J. Bouwstra, G. Gooris, J. Thewalt, 1997, Biochemistry.

The role of ceramides 1 and 2 in the stratum corneum lipid organisation.

J. Bouwstra, G. Gooris, A. Weerheim, 1996, Biochimica et biophysica acta.

Arrangement of Ceramides in the Skin: Sphingosine Chains Localize at a Single Position in Stratum Corneum Lipid Matrix Models

D. Barlow, J. Bouwstra, G. Gooris, 2020, Langmuir : the ACS journal of surfaces and colloids.

Lipid to protein ratio plays an important role in the skin barrier function in patients with atopic eczema

G. Puppels, A. Lavrijsen, J. Bouwstra, 2014, The British journal of dermatology.

Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition.

R. Vreeken, A. Lavrijsen, J. Bouwstra, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition.

S. Kežić, R. Vreeken, J. Bouwstra, 2017, Journal of dermatological science.

Selectivity in cornified envelop binding of ceramides in human skin and the role of LXR inactivation on ceramide binding.

J. Bouwstra, W. Boiten, J. van Smeden, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

From the Structure of the Skin Barrier and Dermal Formulations to in vitro Transport Models for Skin Absorption: Skin Research in the Netherlands and in Germany

M. Windbergs, J. Bouwstra, C. Lehr, 2013, Skin Pharmacology and Physiology.

Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques

A. Boyle, W. Jiskoot, J. Bouwstra, 2020, Advanced healthcare materials.

Hydrophilic and lipophilic moisturizers have similar penetration profiles but different effects on SC water distribution in vivo

J. Bouwstra, G. Gooris, J. Wiechers, 2009, Experimental dermatology.

The in vivo transport of elastic vesicles into human skin: effects of occlusion, volume and duration of application.

J. Bouwstra, A. D. de Graaff, P. Honeywell-Nguyen, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Phase behavior of isolated skin lipids.

J. Bouwstra, G. Gooris, A. Weerheim, 1996, Journal of lipid research.

Coated and Hollow Microneedle-Mediated Intradermal Immunization in Mice with Diphtheria Toxoid Loaded Mesoporous Silica Nanoparticles

Koen van der Maaden, Gideon Kersten, Alexander Kros, 2018, Pharmaceutical Research.

Layer-by-Layer Assembly of Inactivated Poliovirus and N-Trimethyl Chitosan on pH-Sensitive Microneedles for Dermal Vaccination.

Koen van der Maaden, Joke Bouwstra, Gideon Kersten, 2015, Langmuir : the ACS journal of surfaces and colloids.

Electron diffraction study of lipids in non-lesional stratum corneum of atopic eczema patients.

A. Koster, R. Wolterbeek, A. Lavrijsen, 2013, Biochimica et biophysica acta.

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients[S]

T. Hankemeier, S. Kežić, R. Wolterbeek, 2012, Journal of Lipid Research.

Pharmacokinetics and pharmacodynamics analysis of transdermal iontophoresis of 5-OH-DPAT in rats: in vitro-in vivo correlation.

H. Wikström, M. Danhof, J. Bouwstra, 2006, Journal of pharmaceutical sciences.

Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging.

J. Bouwstra, G. Gooris, H. Wenck, 2000, The Journal of investigative dermatology.

The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients

R. Vreeken, A. Lavrijsen, J. Bouwstra, 2014, Experimental dermatology.

Immunogenicity of diphtheria toxoid and poly(I:C) loaded cationic liposomes after hollow microneedle‐mediated intradermal injection in mice

W. Jiskoot, J. Bouwstra, G. Kersten, 2018, International journal of pharmaceutics.

New Aspects of the Skin Barrier Organization

J. Bouwstra, G. Gooris, M. Ponec, 2001, Skin Pharmacology and Physiology.

Changes in the Structure of the Human Stratum Corneum Induced by Liposomes

H. Junginger, J. Bouwstra, G. Gooris, 1992 .

Barrier properties of an N/TERT-based human skin equivalent.

J. Bouwstra, A. Mulder, A. El Ghalbzouri, 2014, Tissue engineering. Part A.

The effect of PPAR isoform (de)activation on the lipid composition in full‐thickness skin models

J. Bouwstra, A. El Ghalbzouri, W. Boiten, 2022, Experimental dermatology.

Improved epidermal barrier formation in human skin models by chitosan modulated dermal matrices

J. Bouwstra, A. El Ghalbzouri, M. Rietveld, 2017, PloS one.

Combined LC/MS-platform for analysis of all major stratum corneum lipids, and the profiling of skin substitutes.

T. Hankemeier, R. Vreeken, J. Bouwstra, 2014, Biochimica et biophysica acta.

Model membranes prepared with ceramide EOS, cholesterol and free fatty acids form a unique lamellar phase.

J. Bouwstra, G. Gooris, D. Groen, 2010, Langmuir : the ACS journal of surfaces and colloids.

Phase behavior of lipid mixtures based on human ceramides: coexistence of crystalline and liquid phases.

J. Bouwstra, G. Gooris, M. Ponec, 2001, Journal of lipid research.

Water mobility and structure in poly[2-hydroxyethylmethacrylate] hydrogels by means of the pulsed field gradient NMR technique.

H. Junginger, J. Bouwstra, J. Leyte, 1993, Biomaterials.

Changes in the internal structure of hydrogels

H. Junginger, J. Bouwstra, M. A. Vries, 1987 .

Polymer-water interactions in cross-linked gels determined by calorimetric measurements

J. Bouwstra, J. C. Miltenburg, W. Roorda, 1987 .

Knock‐down of filaggrin does not affect lipid organization and composition in stratum corneum of reconstructed human skin equivalents

J. Bouwstra, A. Mulder, A. El Ghalbzouri, 2013, Experimental dermatology.

Cationic Liposomes Loaded with a Synthetic Long Peptide and Poly(I:C): a Defined Adjuvanted Vaccine for Induction of Antigen-Specific T Cell Cytotoxicity

W. Jiskoot, J. Bouwstra, F. Ossendorp, 2014, The AAPS Journal.

Interaction of Lipophilic Moisturizers on Stratum Corneum Lipid Domains in vitro and in vivo

J. Bouwstra, G. Gooris, J. Wiechers, 2007, Skin Pharmacology and Physiology.

Immune Modulation by Adjuvants Combined with Diphtheria Toxoid Administered Topically in BALB/c Mice After Microneedle Array Pretreatment

W. Jiskoot, J. Bouwstra, G. Kersten, 2009, Pharmaceutical Research.

Changes in lipid organisation of the skin barrier by N-alkyl-azocycloheptanones : a visualisation and X-ray diffraction study

J. Bouwstra, G. Gooris, M. A. Vries, 1996 .

Animal models for cutaneous vaccine delivery.

J. Bouwstra, G. Kersten, E. van Riet, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Microneedle-Based Transcutaneous Immunisation in Mice with N-Trimethyl Chitosan Adjuvanted Diphtheria Toxoid Formulations

W. Jiskoot, J. Bouwstra, G. Kersten, 2010, Pharmaceutical Research.

Altered lipid properties of the stratum corneum in Canine Atopic Dermatitis.

J. Bouwstra, G. Gooris, F. Broere, 2018, Biochimica et biophysica acta. Biomembranes.

Improved Oral Peptide Delivery by Means of Mucoadhesion

H. Junginger, J. Bouwstra, C. Lehr, 1990 .

THE USE OF A STAGGERED HERRINGBONE MICROMIXER FOR THE PREPARATION OF RIGID LIPOSOMAL FORMULATIONS ALLOWS EFFICIENT ENCAPSULATION OF ANTIGEN AND ADJUVANT.

W. Jiskoot, J. Bouwstra, A. Kros, 2022, Journal of pharmaceutical sciences.

Barrier lipid composition and response to plasma lipids: A direct comparison of mouse dorsal back and ear skin

J. Bouwstra, M. Van Eck, S. Absalah, 2020, Experimental dermatology.

Skin lipids: localization of ceramide and fatty acid in the unit cell of the long periodicity phase.

D. Barlow, J. Bouwstra, G. Gooris, 2015, Biophysical journal.

In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids.

J. Bouwstra, G. Gooris, M. Boncheva, 2014, Biochimica et biophysica acta.

Localization of cholesterol and fatty acid in a model lipid membrane: a neutron diffraction approach.

D. Barlow, J. Bouwstra, G. Gooris, 2013, Biophysical journal.

Lanolin-derived lipid mixtures mimic closely the lipid composition and organization of vernix caseosa lipids.

W. Hennink, J. Bouwstra, M. Ponec, 2008, Biochimica et biophysica acta.

Transdermal Iontophoresis of Rotigotine Across Human Stratum Corneum in Vitro: Influence of pH and NaCl Concentration

Meindert Danhof, Akhmad Kharis Nugroho, M. Danhof, 2004, Pharmaceutical Research.

Phase behavior of stratum corneum lipids in mixed Langmuir-Blodgett monolayers.

J. Bouwstra, M. Ponec, R. Demel, 1996, Biophysical journal.

Binary common-anion alkali halide mixtures correlation of thermochemical and phase-diagram data

J. Bouwstra, H. Oonk, P. V. Ekeren, 1986 .

Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely.

J. Bouwstra, G. Gooris, Joke A Bouwstra, 2008, Biochimica et biophysica acta.

A New Method to Determine the Distribution of a Fluorophore in Scalp Skin with Focus on Hair Follicles

J. Bouwstra, Y. Grams, 2002, Pharmaceutical Research.

Time and depth resolved visualisation of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin.

J. Bouwstra, Y. Grams, L. Whitehead, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin.

J. Bouwstra, Y. Grams, L. Whitehead, 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A Cross-Section Device To Improve Visualization of Fluorescent Probe Penetration into the Skin by Confocal Laser Scanning Microscopy

H. Junginger, J. Bouwstra, C. Cullander, 1998, Pharmaceutical Research.

The Importance of Free Fatty Chain Length on the Lipid Organization in the Long Periodicity Phase

M. Malfois, J. Bouwstra, G. Gooris, 2021, International journal of molecular sciences.

Determination of the influence of C24 D/(2R)- and L/(2S)-isomers of the CER[AP] on the lamellar structure of stratum corneum model systems using neutron diffraction.

R. Neubert, J. Bouwstra, G. Gooris, 2017, Chemistry and physics of lipids.

Lipid Bilayer-Coated Mesoporous Silica Nanoparticles Carrying Bovine Hemoglobin as 1 an Erythrocyte Mimic 2 3

J. Bouwstra, J. Tu, J. Bussmann, 2018 .

PERSPECTIVE AND CONSENSUS OPINION: GOOD PRACTICES FOR USING ORGANOTYPIC SKIN/EPIDERMAL EQUIVALENTS IN EXPERIMENTAL DERMATOLOGY RESEARCH.

M. Tomic-Canic, J. Bouwstra, D. Ilic, 2020, The Journal of investigative dermatology.

Free fatty acids chain length distribution affects the permeability of skin lipid model membranes.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2016, Biochimica et biophysica acta.

The Effect of Two Azones on the Lateral Lipid Organization of Human Stratum Corneum and Its Permeability

J. Bouwstra, H. Koerten, G. Pilgram, 2000, Pharmaceutical Research.

In vitro analysis of QSAR in wanted and unwanted effects of azacycloheptanones as transdermal penetration enhancers

A. IJzerman, J. Bouwstra, H. Boddé, 1993 .

Staphylococcus aureus Extracellular Protease Causes Epidermal Barrier Dysfunction

R. G. Snyder, H. Mantsch, J. Bouwstra, 2010 .

Fabrication of uniformly shaped hydrogel microparticles based on crosslinked hyperbranched polyglycerol by micromolding and photolithographic methods

W. Hennink, J. Bouwstra, D. Broer, 2008 .

Elastic Vesicles as a Tool for Dermal and Transdermal Delivery

J. Bouwstra, H. W. Wouter Groenink, P. Loan Honeywell-Nguyen, 2006, Journal of liposome research.

Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, Biochimica et biophysica acta.

The Lipid Organisation in Human Stratum Corneum and Model Systems

J. Bouwstra, G. Gooris, 2010 .

Elastic vesicles: interaction with human skin and drug transport.

J. Bouwstra, A. D. de Graaff, Loan Honeywell, 2002, Cellular & molecular biology letters.

Modulation of stratum corneum lipid composition and organization of human skin equivalents by specific medium supplements

R. Vreeken, J. Bouwstra, G. Gooris, 2015, Experimental dermatology.

Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema.

S. Kežić, R. Vreeken, A. Lavrijsen, 2011, The Journal of investigative dermatology.

SPECIFIC MEDIUM SUPPLEMENTS

R. Vreeken, J. Bouwstra, G. Gooris, 2012 .

Quantitative assessment of the transport of elastic and rigid vesicle components and a model drug from these vesicle formulations into human skin in vivo.

J. Bouwstra, G. Gooris, P. Honeywell-Nguyen, 2004, The Journal of investigative dermatology.

Preparation and characterization of structured hydrogel microparticles based on cross-linked hyperbranched polyglycerol.

W. Hennink, J. Bouwstra, D. Broer, 2007, Langmuir : the ACS journal of surfaces and colloids.

Encapsulation of lidocaine base and hydrochloride into non-ionic surfactant vesicles (NSVs) and diffusion through human stratum corneum in vitro

H. Junginger, J. Bouwstra, D. A. V. Hal, 1996 .

In vitro human skin barrier perturbation by oleic acid: Thermal analysis and freeze fracture electron microscopy studies

H. Junginger, J. Bouwstra, H. Tanojo, 1997 .

P258 interactions of bile salts with non-ionic surfactant vesicles

H. Junginger, J. Bouwstra, C. Rentel, 1994 .

Barrier Capability of Skin Lipid Models: Effect of Ceramides and Free Fatty Acid Composition.

J. Bouwstra, C. Beddoes, Charlotte M Beddoes, 2019, Langmuir : the ACS journal of surfaces and colloids.

The effect of surfactant-based elastic and rigid vesicles on the penetration of lidocaine across human skin

H. Junginger, J. Bouwstra, P. Honeywell-Nguyen, 2002 .

The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2014, Biochimica et biophysica acta.

NONIONIC SURFACTANT VESICLES CONTAINING ESTRADIOL FOR TOPICAL APPLICATION

H. Junginger, J. Bouwstra, D. A. V. Hal, 1996 .

P256 electroperturbation of the human skin barrier in vitro: effects on stratum corneum resistance, capacitance, lipid ordering and ultrastructure

H. Junginger, J. Bouwstra, G. Gooris, 1994 .

Preparation and characterization of diphtheria toxoid-loaded elastic vesicles for transcutaneous immunization

W. Jiskoot, J. Bouwstra, M. Bivas-Benita, 2008, Journal of drug targeting (Print).

Physicochemical characterization of drug-loaded rigid and elastic vesicles.

J. Bouwstra, G. Gooris, T. Uchino, 2011, International journal of pharmaceutics.

Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models

M. Malfois, J. Bouwstra, C. Beddoes, 2023, Journal of lipid research.

Lipid to protein ratio plays an important role in the skin barrier function in patients with atopic eczema

A. Lavrijsen, J. Bouwstra, P. Caspers, 2014 .

Applying a vernix caseosa based formulation accelerates skin barrier repair by modulating lipid biosynthesis[S]

A. Lavrijsen, J. Bouwstra, S. Absalah, 2017, Journal of Lipid Research.

Solid and fluid segments within the same molecule of stratum corneum ceramide lipid

D. Topgaard, J. Bouwstra, G. Gooris, 2018, Quarterly Reviews of Biophysics.

Increased Levels of Short-Chain Ceramides Modify the Lipid Organization and Reduce the Lipid Barrier of Skin Model Membranes

J. Bouwstra, C. Beddoes, Charlotte M Beddoes, 2021, Langmuir : the ACS journal of surfaces and colloids.

Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro

A. Lavrijsen, J. Bouwstra, A. Mulder, 2015, Cell and Tissue Research.

BBA - Molecular and Cell Biology of Lipids Hypercholesterolemia in young adult APOE − / − mice alters epidermal lipid composition and impairs barrier function

J. Bouwstra, G. Gooris, M. Hoekstra, 2019 .

Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.

J. Bouwstra, J. van Smeden, Jeroen van Smeden, 2016, Current problems in dermatology.

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.

J. Bouwstra, G. Gooris, A. Weerheim, 1995, Journal of lipid research.

Knock‐down of filaggrin does not affect lipid organization and composition in stratum corneum of reconstructed human skin equivalents

J. Bouwstra, A. Mulder, A. El Ghalbzouri, 2013, Experimental Dermatology.

The skin barrier: An extraordinary interface with an exceptional lipid organization.

J. Bouwstra, G. Gooris, Andreea Nădăban, 2023, Progress in lipid research.

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery[S]

T. Hankemeier, R. Vreeken, J. Bouwstra, 2011, Journal of Lipid Research.

Monitoring the penetration process of single microneedles with varying tip diameters.

Cwj Cees Oomens, J. Bouwstra, Am Anne Römgens, 2014, Journal of the mechanical behavior of biomedical materials.

Psoriasis-Associated Late Cornified Envelope (LCE) Proteins Have Antibacterial Activity.

James T. Elder, P. Jansen, J. Bouwstra, 2017, The Journal of investigative dermatology.

Co-encapsulation of antigen and Toll-like receptor ligand in cationic liposomes affects the quality of the immune response in mice after intradermal vaccination.

W. Jiskoot, J. Bouwstra, S. Bal, 2011, Vaccine.

Nanolayered chemical modification of silicon surfaces with ionizable surface groups for pH-triggered protein adsorption and release: application to microneedles.

W. Jiskoot, J. Bouwstra, A. Kros, 2013, Journal of materials chemistry. B.

Investigating the barrier function of skin lipid models with varying compositions.

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Lanolin-derived lipid mixtures mimic closely the lipid composition and organization of vernix caseosa lipids.

W. Hennink, J. Bouwstra, M. Ponec, 2008, Biochimica et biophysica acta.

Properties of mixed crystalline organic material prepared by zone levelling III. Vapour pressures of (trans-azobenzene + trans-stilbene)

C. G. D. Kruif, J. Bouwstra, H. Oonk, 1984 .

Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, Biochimica et biophysica acta.

X-Ray Microanalysis of Cryopreserved Human Skin to Study the Effect of Iontophoresis on Percutaneous Ion Transport1

H. Junginger, J. Bouwstra, H. Boddé, 2001, Pharmaceutical Research.

Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely.

J. Bouwstra, G. Gooris, J. Caussin, 2008, Biochimica et biophysica acta.

Shedding light on the effects of 1,25-dihydroxyvitamin D3 on epidermal lipid barrier formation in three-dimensional human skin equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

THE CORNIFIED ENVELOPE BOUND CERAMIDE FRACTION IS ALTERED IN ATOPIC DERMATITIS PATIENTS.

J. Bouwstra, Walter A Boiten, Jeroen van Smeden, 2020, The Journal of investigative dermatology.

The in vitro and in vivo evaluation of new synthesized prodrugs of 5-OH-DPAT for iontophoretic delivery.

J. Bouwstra, O. Pasqua, M. Danhof, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Vesicles as a tool for transdermal and dermal delivery.

J. Bouwstra, P. Honeywell‐Nguyen, 2005, Drug discovery today. Technologies.

Diffusion profile of macromolecules within and between human skin layers for (trans)dermal drug delivery.

C. Oomens, F. Baaijens, D. Bader, 2015, Journal of The Mechanical Behavior of Biomedical Materials.

Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial

J. Bouwstra, M. D. de Kam, J. Burggraaf, 2023, International journal of molecular sciences.

The Lipid Organization in Stratum Corneum and Model Systems Based on Ceramides

J. Bouwstra, M. Ponec, M. Jager, 2006 .

Predicting the optimal geometry of microneedles and their array for dermal vaccination using a computational model

C. Oomens, D. Bader, J. Bouwstra, 2016, Computer methods in biomechanics and biomedical engineering.

Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles

J. Bouwstra, B. Slütter, K. van der Maaden, 2024, Pharmaceutical research.

The physico-chemical characterization of poly (2-hydroxyethyl methacrylate-co-methacrylic acid: 2. Effect of water, PEG 400 and PEG 6000 on the glass transition temperature

H. Junginger, J. Bouwstra, J. Verhoeven, 1989 .

Infrared spectroscopy studies of mixtures prepared with synthetic ceramides varying in head group architecture: coexistence of liquid and crystalline phases.

J. Bouwstra, G. Gooris, M. Janssens, 2009, Biochimica et biophysica acta.