G. Gooris

J. Bouwstra, G. Gooris, T. Uchino, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Ceramides in the skin lipid membranes: length matters.

J. Bouwstra, G. Gooris, P. Slepička, 2013, Langmuir : the ACS journal of surfaces and colloids.

Lipophilic and hydrophilic moisturizers show different actions on human skin as revealed by cryo scanning electron microscopy

J. Bouwstra, G. Gooris, J. Wiechers, 2007, Experimental dermatology.

The lipid organisation in the skin barrier.

J. Bouwstra, G. Gooris, M. Ponec, 2000, Acta dermato-venereologica. Supplementum.

The influence of two azones and sebaceous lipids on the lateral organization of lipids isolated from human stratum corneum.

J. Bouwstra, G. Gooris, H. Koerten, 2001, Biochimica et biophysica acta.

Structure of human stratum corneum as a function of temperature and hydration a wide-angle X-ray diffraction study

J. Bouwstra, G. Gooris, W. Bras, 1992 .

pH, cholesterol sulfate, and fatty acids affect the stratum corneum lipid organization.

J. Bouwstra, G. Gooris, A. Weerheim, 1998, The journal of investigative dermatology. Symposium proceedings.

Lipid organization in pig stratum corneum.

D. Downing, J. Bouwstra, G. Gooris, 1995, Journal of lipid research.

Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Formation in Human Skin Equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, International journal of molecular sciences.

The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C.

J. Bouwstra, G. Gooris, A. Weerheim, 1997, The Journal of investigative dermatology.

Hypercholesterolemia in young adult APOE-/- mice alters epidermal lipid composition and impairs barrier function.

J. Bouwstra, G. Gooris, M. Hoekstra, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Hyperalphalipoproteinemic scavenger receptor BI knockout mice exhibit a disrupted epidermal lipid barrier.

J. Bouwstra, G. Gooris, M. Hoekstra, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Multitargeted Approach for the Optimization of Morphogenesis and Barrier Formation in Human Skin Equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2021, International journal of molecular sciences.

Physicochemical characterization of drug-loaded rigid and elastic vesicles.

J. Bouwstra, G. Gooris, T. Uchino, 2011, International journal of pharmaceutics.

Small angle X-ray scattering: possibilities and limitations in characterization of vesicles.

J. Bouwstra, G. Gooris, W. Bras, 1993, Chemistry and physics of lipids.

The importance of ceramide headgroup for lipid localisation in skin lipid models.

D. Barlow, M. Malfois, J. Bouwstra, 2022, Biochimica et biophysica acta. Biomembranes.

Shedding light on the effects of 1,25-dihydroxyvitamin D3 on epidermal lipid barrier formation in three-dimensional human skin equivalents

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Stratum lipid matrix: location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase

D. Barlow, G. Gooris, M. Lawrence, 2016 .

Monounsaturated fatty acids reduce the barrier of stratum corneum lipid membranes by enhancing the formation of a hexagonal lateral packing.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2014, Langmuir : the ACS journal of surfaces and colloids.

Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I).

J. Bouwstra, G. Gooris, Diógenes de Sousa Neto, 2011, Chemistry and physics of lipids.

Long periodicity phase in extracted lipids of vernix caseosa obtained with equilibration at physiological temperature.

J. Bouwstra, G. Gooris, M. Ponec, 2009, Chemistry and physics of lipids.

Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction.

J. Bouwstra, G. Gooris, A. Weerheim, 1995, Journal of lipid research.

The lipid and protein structure of mouse stratum corneum: a wide and small angle diffraction study.

J. Bouwstra, G. Gooris, W. Bras, 1994, Biochimica et biophysica acta.

Lipid arrangements in human stratum corneum

G. Gooris, W. Bras, J. V. D. Spek, 1992 .

One Peptide for Them All: Gold Nanoparticles of Different Sizes Are Stabilized by a Common Peptide Amphiphile

A. Boyle, J. Bouwstra, G. Gooris, 2020, ACS nano.

Interactions of dipalmitoylphosphatidylcholine with ceramide-based mixtures.

J. Bouwstra, G. Gooris, A. Kros, 2018, Biochimica et biophysica acta. Biomembranes.

Effect of electrolyte on the phase behavior and emulsion stability in the system didodecyldimethylammonium bromide (DDAB)/dodecane/water

J. Bouwstra, G. Gooris, J. Sjöblom, 1992 .

Structure of the skin barrier and its modulation by vesicular formulations.

J. Bouwstra, G. Gooris, M. Ponec, 2003, Progress in lipid research.

The effect of the chain length distribution of free fatty acids on the mixing properties of stratum corneum model membranes.

J. Bouwstra, G. Gooris, K. Bito, 2014, Biochimica et biophysica acta.

Water distribution and related morphology in human stratum corneum at different hydration levels.

Johann W Wiechers, J. Bouwstra, G. Gooris, 2003, The Journal of investigative dermatology.

Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range.

J. Bouwstra, G. Gooris, M. Ponec, 1999, Journal of lipid research.

New insights into the stratum corneum lipid organization by X-ray diffraction analysis.

J. Bouwstra, G. Gooris, D. Groen, 2009, Biophysical journal.

Lipid mixtures prepared with well-defined synthetic ceramides closely mimic the unique stratum corneum lipid phase behavior Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500221-JLR200

J. Bouwstra, G. Gooris, M. Ponec, 2005, Journal of Lipid Research.

Modelling the stratum corneum lipid organisation with synthetic lipid mixtures: the importance of synthetic ceramide composition.

J. Bouwstra, G. Gooris, M. Ponec, 2004, Biochimica et biophysica acta.

The important role of stratum corneum lipids for the cutaneous barrier function.

J. Bouwstra, G. Gooris, J. van Smeden, 2014, Biochimica et biophysica acta.

Role of ceramide 1 in the molecular organization of the stratum corneum lipids.

A. IJzerman, J. Bouwstra, G. Gooris, 1998, Journal of lipid research.

Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin

J. Bouwstra, G. Gooris, T. Berkers, 2018, Pharmaceutical Research.

Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies.

J. Bouwstra, G. Gooris, M. Ponec, 2006, Biochimica et biophysica acta.

Nonionic Surfactant Vesicles: A Study of Vesicle Formation, Characterization, and Stability

H. Junginger, J. Bouwstra, G. Gooris, 1993 .

Temperature-induced changes in structural and physicochemical properties of vernix caseosa.

W. Hennink, J. Bouwstra, G. Gooris, 2008, The Journal of investigative dermatology.

Transdermal Macromolecular Delivery: Real-Time Visualisation of Iontophoretic and Chemically Enhanced Transport Using Two-Photon Excitation Microscopy

W. J. Irwin, A. Naik, J. Bouwstra, 2000, Pharmaceutical Research.

The influence of alkyl-azones on the ordering of the lamellae in human stratum corneum

J. Brussee, J. Bouwstra, G. Gooris, 1992 .

Electroperturbation of the human skin barrier in vitro: II. Effects on stratum corneum lipid ordering and ultrastructure

H. Junginger, J. Bouwstra, G. Gooris, 1997, Microscopy research and technique.

Modes of action of terpene penetration enhancers in human skin; Differential scanning calorimetry, small-angle X-ray diffraction and enhancer uptake studies

J. Bouwstra, G. Gooris, B. W. Barry, 1996 .

Investigating the barrier function of skin lipid models with varying compositions.

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Infrared spectroscopy studies of mixtures prepared with synthetic ceramides varying in head group architecture: coexistence of liquid and crystalline phases.

J. Bouwstra, G. Gooris, M. Janssens, 2009, Biochimica et biophysica acta.

Acylceramide head group architecture affects lipid organization in synthetic ceramide mixtures.

J. Bouwstra, G. Gooris, M. Ponec, 2004, The Journal of investigative dermatology.

Novel lipid mixtures based on synthetic ceramides reproduce the unique stratum corneum lipid organization Published, JLR Papers in Press, February 16, 2004. DOI 10.1194/jlr.M300484-JLR200

J. Bouwstra, G. Gooris, M. Ponec, 2004, Journal of Lipid Research.

The phase behaviour of skin lipid mixtures based on synthetic ceramides.

J. Bouwstra, G. Gooris, M. Ponec, 2003, Chemistry and physics of lipids.

FTIR studies show lipophilic moisturizers to interact with stratum corneum lipids, rendering the more densely packed.

J. Bouwstra, G. Gooris, J. Caussin, 2008, Biochimica et biophysica acta.

Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum.

J. Bouwstra, G. Gooris, T. Berkers, 2018, Acta dermato-venereologica.

Stratum corneum lipid matrix: Location of acyl ceramide and cholesterol in the unit cell of the long periodicity phase.

D. Barlow, J. Bouwstra, G. Gooris, 2016, Biochimica et biophysica acta.

Disposition of ceramide in model lipid membranes determined by neutron diffraction.

D. Barlow, J. Bouwstra, G. Gooris, 2011, Biophysical journal.

Infrared spectroscopic study of stratum corneum model membranes prepared from human ceramides, cholesterol, and fatty acids.

J. Bouwstra, G. Gooris, 2007, Biophysical journal.

Phase behavior of stratum corneum lipid mixtures based on human ceramides: the role of natural and synthetic ceramide 1.

J. Bouwstra, G. Gooris, F. E. Dubbelaar, 2002, The Journal of investigative dermatology.

A structural study of the mesophases of two oxyethylene alkyl ether-decane-water systems, a comparison between technical grade C12EO〈7〉 and pure C12EO6

J. Bouwstra, G. Gooris, F. Spies, 1989 .

Changes of mesophase structure of BRIJ 96/water mixtures on addition of liquid paraffin

G. Gooris, H. Junginger, H. Jousma, 1989 .

Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents.

J. Bouwstra, G. Gooris, A. Mulder, 2015, Journal of dermatological science.

Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formation

J. Bouwstra, G. Gooris, A. El Ghalbzouri, 2019, Scientific Reports.

Evidence of hydrocarbon nanodrops in highly ordered stratum corneum model membranes[S]

M. Lafleur, J. Bouwstra, G. Gooris, 2017, Journal of Lipid Research.

The role of ceramide composition in the lipid organisation of the skin barrier.

J. Bouwstra, G. Gooris, A. Weerheim, 1999, Biochimica et biophysica acta.

A model membrane approach to the epidermal permeability barrier: an X-ray diffraction study.

J. Bouwstra, G. Gooris, J. Thewalt, 1997, Biochemistry.

The role of ceramides 1 and 2 in the stratum corneum lipid organisation.

J. Bouwstra, G. Gooris, A. Weerheim, 1996, Biochimica et biophysica acta.

Arrangement of Ceramides in the Skin: Sphingosine Chains Localize at a Single Position in Stratum Corneum Lipid Matrix Models

D. Barlow, J. Bouwstra, G. Gooris, 2020, Langmuir : the ACS journal of surfaces and colloids.

Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition.

S. Kežić, R. Vreeken, J. Bouwstra, 2017, Journal of dermatological science.

Hydrophilic and lipophilic moisturizers have similar penetration profiles but different effects on SC water distribution in vivo

J. Bouwstra, G. Gooris, J. Wiechers, 2009, Experimental dermatology.

Phase behavior of isolated skin lipids.

J. Bouwstra, G. Gooris, A. Weerheim, 1996, Journal of lipid research.

Increase in short-chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients[S]

T. Hankemeier, S. Kežić, R. Wolterbeek, 2012, Journal of Lipid Research.

Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging.

J. Bouwstra, G. Gooris, H. Wenck, 2000, The Journal of investigative dermatology.

Effect of divalent cations on lipid organization of cardiolipin isolated from Escherichia coli strain AH930.

J. Killian, G. Gooris, B. de Kruijff, 1994, Biochimica et biophysica acta.

New Aspects of the Skin Barrier Organization

J. Bouwstra, G. Gooris, M. Ponec, 2001, Skin Pharmacology and Physiology.

Changes in the Structure of the Human Stratum Corneum Induced by Liposomes

H. Junginger, J. Bouwstra, G. Gooris, 1992 .

Model membranes prepared with ceramide EOS, cholesterol and free fatty acids form a unique lamellar phase.

J. Bouwstra, G. Gooris, D. Groen, 2010, Langmuir : the ACS journal of surfaces and colloids.

Phase behavior of lipid mixtures based on human ceramides: coexistence of crystalline and liquid phases.

J. Bouwstra, G. Gooris, M. Ponec, 2001, Journal of lipid research.

Interaction of Lipophilic Moisturizers on Stratum Corneum Lipid Domains in vitro and in vivo

J. Bouwstra, G. Gooris, J. Wiechers, 2007, Skin Pharmacology and Physiology.

Changes in lipid organisation of the skin barrier by N-alkyl-azocycloheptanones : a visualisation and X-ray diffraction study

J. Bouwstra, G. Gooris, M. A. Vries, 1996 .

Altered lipid properties of the stratum corneum in Canine Atopic Dermatitis.

J. Bouwstra, G. Gooris, F. Broere, 2018, Biochimica et biophysica acta. Biomembranes.

Skin lipids: localization of ceramide and fatty acid in the unit cell of the long periodicity phase.

D. Barlow, J. Bouwstra, G. Gooris, 2015, Biophysical journal.

In vitro model systems for studying the impact of organic chemicals on the skin barrier lipids.

J. Bouwstra, G. Gooris, M. Boncheva, 2014, Biochimica et biophysica acta.

Localization of cholesterol and fatty acid in a model lipid membrane: a neutron diffraction approach.

D. Barlow, J. Bouwstra, G. Gooris, 2013, Biophysical journal.

Lipid organization in human and porcine stratum corneum differs widely, while lipid mixtures with porcine ceramides model human stratum corneum lipid organization very closely.

J. Bouwstra, G. Gooris, Joke A Bouwstra, 2008, Biochimica et biophysica acta.

The Importance of Free Fatty Chain Length on the Lipid Organization in the Long Periodicity Phase

M. Malfois, J. Bouwstra, G. Gooris, 2021, International journal of molecular sciences.

Determination of the influence of C24 D/(2R)- and L/(2S)-isomers of the CER[AP] on the lamellar structure of stratum corneum model systems using neutron diffraction.

R. Neubert, J. Bouwstra, G. Gooris, 2017, Chemistry and physics of lipids.

Free fatty acids chain length distribution affects the permeability of skin lipid model membranes.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2016, Biochimica et biophysica acta.

Staphylococcus aureus Extracellular Protease Causes Epidermal Barrier Dysfunction

R. G. Snyder, H. Mantsch, J. Bouwstra, 2010 .

Is an orthorhombic lateral packing and a proper lamellar organization important for the skin barrier function?

Dana S. Poole, J. Bouwstra, G. Gooris, 2011, Biochimica et biophysica acta.

The Lipid Organisation in Human Stratum Corneum and Model Systems

J. Bouwstra, G. Gooris, 2010 .

Modulation of stratum corneum lipid composition and organization of human skin equivalents by specific medium supplements

R. Vreeken, J. Bouwstra, G. Gooris, 2015, Experimental dermatology.

Lamellar lipid organization and ceramide composition in the stratum corneum of patients with atopic eczema.

S. Kežić, R. Vreeken, A. Lavrijsen, 2011, The Journal of investigative dermatology.

SPECIFIC MEDIUM SUPPLEMENTS

R. Vreeken, J. Bouwstra, G. Gooris, 2012 .

Quantitative assessment of the transport of elastic and rigid vesicle components and a model drug from these vesicle formulations into human skin in vivo.

J. Bouwstra, G. Gooris, P. Honeywell-Nguyen, 2004, The Journal of investigative dermatology.

The role of ceramide chain length distribution on the barrier properties of the skin lipid membranes.

J. Bouwstra, G. Gooris, E. H. Mojumdar, 2014, Biochimica et biophysica acta.

P256 electroperturbation of the human skin barrier in vitro: effects on stratum corneum resistance, capacitance, lipid ordering and ultrastructure

H. Junginger, J. Bouwstra, G. Gooris, 1994 .

Physicochemical characterization of drug-loaded rigid and elastic vesicles.

J. Bouwstra, G. Gooris, T. Uchino, 2011, International journal of pharmaceutics.

Phase behaviour of skin barrier model membranes at pH 7.4.

G. Gooris, M. Ponec, F. E. Dubbelaar, 2000, Cellular and molecular biology.

Solid and fluid segments within the same molecule of stratum corneum ceramide lipid

D. Topgaard, J. Bouwstra, G. Gooris, 2018, Quarterly Reviews of Biophysics.

BBA - Molecular and Cell Biology of Lipids Hypercholesterolemia in young adult APOE − / − mice alters epidermal lipid composition and impairs barrier function

J. Bouwstra, G. Gooris, M. Hoekstra, 2019 .