A. Cupo

发表

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Chaim A. Schramm, Cinque S. Soto, J. Mullikin, 2014, Nature.

SOSIP Envelope Glycoprotein Aggregation of Soluble, Cleaved HIV-1 Influences on Trimerization and

John P. Moore, I. Wilson, A. Ward, 2014 .

Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein

John P. Moore, I. Wilson, A. Ward, 2013, Journal of Virology.

A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies

John P. Moore, I. Wilson, T. Ketas, 2013, PLoS pathogens.

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

John P. Moore, D. Burton, I. Wilson, 2013, Science.

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

John P. Moore, D. Burton, I. Wilson, 2013, Science.

Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin

John P. Moore, I. Wilson, M. Nussenzweig, 2019, Journal of Virology.

Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies

John P. Moore, D. Burton, I. Wilson, 2014, Cell.

Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

John P. Moore, I. Wilson, Kelly K. Lee, 2015, Nature Communications.

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C

John P. Moore, I. Wilson, D. Montefiori, 2016, PLoS pathogens.

Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike

John P. Moore, J. Pallesen, A. Ward, 2017, Nature.

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9

John P. Moore, I. Wilson, C. D. Murin, 2013, Proceedings of the National Academy of Sciences.

Structure of 2G12 Fab2 in Complex with Soluble and Fully Glycosylated HIV-1 Env by Negative-Stain Single-Particle Electron Microscopy

John P. Moore, D. Burton, I. Wilson, 2014, Journal of Virology.

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate

E. Go, H. Desaire, John P. Moore, 2017, Biotechnology and bioengineering.

Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody

John P. Moore, D. Montefiori, D. Purcell, 2022, Cell reports. Medicine.

Structural Constraints Det ermine the Glycosylation of HIV-1 Envelope Trimers Graphical

John P. Moore, D. Burton, I. Wilson, 2015 .

Virus-like particle (VLP) vaccine conferred complete protection against a lethal influenza virus challenge.

A. Cupo, J. Galarza, Theresa E. Latham, 2005, Viral immunology.

Predictors of Nonseroconversion after SARS-CoV-2 Infection

John P. Moore, P. Bieniasz, T. Ketas, 2021, Emerging infectious diseases.

Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

John P. Moore, I. Wilson, D. Montefiori, 2017, Journal of Virology.

Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva

G. Debnath, John P. Moore, T. Ketas, 2021, Pathogens & immunity.

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

John P. Moore, D. Burton, I. Wilson, 2015, Journal of Virology.

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

John P. Moore, T. Ketas, Helen J Kim, 2014, Retrovirology.

SARS-CoV-2 mRNA vaccination exposes progressive adaptive immune dysfunction in patients with chronic lymphocytic leukemia

T. Ketas, B. Hahn, P. Goepfert, 2022, medRxiv.

SOS and IP Modifications Predominantly Affect the Yield but Not Other Properties of SOSIP.664 HIV-1 Env Glycoprotein Trimers

John P. Moore, A. Ward, A. Cupo, 2019, Journal of Virology.

Partial Enzymatic Deglycosylation Preserves the Structure of Cleaved Recombinant HIV-1 Envelope Glycoprotein Trimers*

John P. Moore, I. Wilson, A. Ward, 2012, The Journal of Biological Chemistry.

Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro

John P. Moore, A. Ward, A. Cupo, 2018, Journal of Virology.

Poliomyelitis in intraspinally inoculated poliovirus receptor transgenic mice.

A. Cupo, R. Taffs, J. Crowley, 1999, Virology.

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

John P. Moore, D. Burton, I. Wilson, 2014, Retrovirology.

A novel intranasal virus-like particle (VLP) vaccine designed to protect against the pandemic 1918 influenza A virus (H1N1).

A. Cupo, J. Galarza, D. Matassov, 2007, Viral immunology.

Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens

John P. Moore, I. Wilson, A. Ward, 2015, Proceedings of the National Academy of Sciences.

Structural Characterization of Cleaved, Soluble HIV-1 Envelope Glycoprotein Trimers

John P. Moore, I. Wilson, A. Ward, 2013, Journal of Virology.

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Ryan McBride, Robyn L. Stanfield, Andrew B. Ward, 2013, PLoS pathogens.

HIV-1 SOSIP envelope glycoprotein 2

John P. Moore, I. Wilson, A. Ward, 2013 .

, Albert Trimers Soluble HIV-1 Envelope Glycoprotein Structural Characterization of Cleaved

John P. Moore, I. Wilson, J. Julien, 2013 .

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

Yan Liu, William R. Schief, Ryan McBride, 2011, Science.

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Yan Liu, Ryan McBride, Robyn L. Stanfield, 2013, Nature Structural &Molecular Biology.

D-101 HIV-1 neutralizing antibodies induced by native-like envelope trimers

G. Debnath, John P. Moore, D. Burton, 2016 .

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

Weston B Struwe, Louise Royle, Ian A Wilson, 2016, Cell reports.

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Daniel W. Kulp, L. Stamatatos, John P. Moore, 2015, Cell.

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

John P. Moore, I. Wilson, Helen J Kim, 2013, Proceedings of the National Academy of Sciences.

Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer

John P. Moore, D. Burton, I. Wilson, 2015, PLoS pathogens.

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits

John P. Moore, D. Burton, A. Ward, 2014, Retrovirology.

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.

James C Paulson, Pascal Poignard, Ian A Wilson, 2014, Immunity.

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

L. Stamatatos, John P. Moore, M. V. van Breemen, 2017, The Journal of experimental medicine.

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

John P. Moore, D. Burton, A. Ward, 2015, Journal of Virology.

Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.

John P. Moore, I. Wilson, A. Ward, 2018, Journal of proteome research.

Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers

E. Go, H. Desaire, Shijian Zhang, 2017, Journal of Virology.

CD4-induced activation in a soluble HIV-1 Env trimer.

John P. Moore, I. Wilson, T. Matsui, 2014, Structure.

Optimizing the production and affinity purification of HIV-1 envelope glycoprotein SOSIP trimers from transiently transfected CHO cells

John P. Moore, A. Cupo, A. Yasmeen, 2019, PloS one.

Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva

G. Debnath, John P. Moore, T. Ketas, 2021, bioRxiv.

Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens

John P. Moore, A. Ward, A. Cupo, 2019, Journal of pharmaceutical sciences.

Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer

John P. Moore, A. Cupo, M. Crispin, 2016, Journal of Virology.

Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers.

Ian A Wilson, Dennis R Burton, John P. Moore, 2015, Cell reports.

Monoclonal antiidiotypic antibodies against delta opioid receptors as an electron microscopy probe.

A. Cupo, M. Eybalin, M. Conrath, 1992, European journal of cell biology.

Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes

John P. Moore, I. Wilson, A. Ward, 2017, Journal of Virology.

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers

E. Go, H. Desaire, John P. Moore, 2015, Journal of Virology.

Microscopyn Single-Particle Electron Soluble and Fully Glycosylated HIV-1 Env in Complex with 2 Structure of 2G12 Fab

John P. Moore, I. Wilson, C. D. Murin, 2014 .

Virus-like particle vaccine conferred complete protection against a lethal influenza virus challenge.

A. Cupo, J. Galarza, Theresa Latham, 2005, Viral immunology.

Stable 293 T and CHO cell lines expressing cleaved, stable HIV-1 envelope glycoprotein trimers for structural and vaccine studies

John P. Moore, I. Wilson, T. Ketas, 2014, Retrovirology.

Chemical Cross-Linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens

Q. Sattentau, John P. Moore, A. Ward, 2015, Journal of Virology.

Exposure of progressive immune dysfunction by SARS-CoV-2 mRNA vaccination in patients with chronic lymphocytic leukemia: A prospective cohort study

T. Ketas, B. Hahn, P. Goepfert, 2023, PLoS medicine.

Native Conformation and Canonical Disulfide Bond Formation Are Interlinked Properties of HIV-1 Env Glycoproteins

E. Go, H. Desaire, John P. Moore, 2015, Journal of Virology.

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Q. Sattentau, John P. Moore, D. Montefiori, 2017, PloS one.

Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike

John P. Moore, A. Ward, A. Cupo, 2020, bioRxiv.

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Daniel W. Kulp, L. Stamatatos, John P. Moore, 2015, Cell.

Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

John P. Moore, D. Burton, A. Ward, 2015, Journal of Virology.

A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene

John P. Moore, D. Burton, I. Wilson, 2015, Journal of Virology.

Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein

John P. Moore, I. Wilson, A. Ward, 2013, Journal of Virology.

HIV-1 neutralizing antibodies induced by native-like envelope trimers

John P. Moore, M. V. van Breemen, D. Montefiori, 2015, Science.

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Q. Sattentau, John P. Moore, D. Montefiori, 2017, PloS one.

Immunization with germ line–targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques

A. Cupo, R. Sanders, K. Wiehe, 2024, Science Immunology.