A. Druz

发表

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Chaim A. Schramm, Cinque S. Soto, J. Mullikin, 2014, Nature.

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Cinque S. Soto, U. Baxa, J. Mullikin, 2016, Cell.

Crystal structure , conformational fixation , and entry-related interactions of mature ligand-free HIV-1 Env

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016 .

Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera

G. Chuang, M. Sastry, I. Georgiev, 2015, Science Translational Medicine.

CHO microRNA engineering is growing up: Recent successes and future challenges☆

David P. Kreil, J. Shiloach, N. Barron, 2013, Biotechnology advances.

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Baoshan Zhang, Edward M Marcotte, Cornelia L Dekker, 2016, Nature Medicine.

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Tongqing Zhou, Baoshan Zhang, Sam Darko, 2016, Immunity.

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Young Do Kwon, Tongqing Zhou, Baoshan Zhang, 2016, Cell.

Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines

Rajarshi Guha, Scott E. Martin, Aliaksandr Druz, 2013, RNA biology.

A novel microRNA mmu‐miR‐466h affects apoptosis regulation in mammalian cells

Aliaksandr Druz, Joseph Shiloach, Michael Betenbaugh, 2011, Biotechnology and bioengineering.

Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

G. Chuang, B. Carragher, C. Potter, 2017, Nature Structural &Molecular Biology.

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.

Cinque S. Soto, B. Haynes, J. Mascola, 2017, Cell reports.

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Alon Herschhorn, J. Sodroski, J. Mascola, 2019, Nature Communications.

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Alon Herschhorn, J. Sodroski, J. Mascola, 2019, Nature Communications.

Longitudinal Analysis Reveals Early Development of Three MPER‐Directed Neutralizing Antibody Lineages from an HIV‐1‐Infected Individual

Jonathan R. McDaniel, Chaim A. Schramm, Kenneth H. Zhou, 2019, Immunity.

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

U. Baxa, R. Geiger, F. Sallusto, 2016, Nature Microbiology.

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

J. Mascola, M. Sastry, I. Georgiev, 2016, Bioconjugate chemistry.

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

J. Mascola, G. Chuang, Reda Rawi, 2020, Scientific Reports.

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

Cinque S. Soto, U. Baxa, J. Mascola, 2016 .

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

U. Baxa, J. Mascola, Y. Lai, 2017, npj Vaccines.

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Lynn Morris, Gwo-Yu Chuang, Peter D. Kwong, 2015, Journal of Virology.

Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation

J. Shiloach, M. Betenbaugh, A. Druz, 2012, Nucleic acids research.

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

B. Haynes, D. Ho, J. Mascola, 2016, Journal of Virology.

MicroRNAs as Engineering Targets: Pathway Manipulation to Impact Bioprocess Phenotypes

J. Shiloach, M. Betenbaugh, A. Druz, 2012 .

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

C. Soto, T. Lemmin, Cinque S. Soto, 2016, Science.

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529

Alon Herschhorn, J. Sodroski, J. Mascola, 2017, Nature chemical biology.

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

Chaim A. Schramm, Cinque S. Soto, T. Kepler, 2016, Cell.

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.

J. Mascola, G. Chuang, L. Morris, 2020, Cell reports.

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1–4

M. Beltramello, U. Baxa, J. Mascola, 2018, Proceedings of the National Academy of Sciences.

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

J. Mascola, D. Burton, M. Connors, 2017, PLoS pathogens.

Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

J. Mascola, M. Sastry, I. Georgiev, 2016, PloS one.

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

J. Mascola, L. Morris, R. Bailer, 2016, Journal of Virology.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Cinque S. Soto, J. Mullikin, B. Haynes, 2015, Cell.

Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

Young Do Kwon, Mario Roederer, Tongqing Zhou, 2014, Journal of Virology.

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface

Gwo-Yu Chuang, Peter D. Kwong, Richard T. Wyatt, 2014, Nature.

Structure and immune recognition of trimeric prefusion HIV-1 Env

Tongqing Zhou, Yongping Yang, Baoshan Zhang, 2014, Nature.

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

J. Mascola, G. Chuang, M. Sastry, 2018, bioRxiv.

Structures of HIV-1-Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Jonathan R. McDaniel, Cinque S. Soto, U. Baxa, 2015, Nature Structural &Molecular Biology.

, In Vivo Infection Improves Protection against Lentiviral In Vitro Neutralizing HIV-1 Antibody Enhanced Potency of a Broadly

Kyle E. Roberts, Cinque S. Soto, B. Donald, 2014 .

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

J. Mascola, Rui Chen, G. Chuang, 2018, Nature Medicine.

Virus‐like Particles Identify an HIV V1V2 Apex‐Binding Neutralizing Antibody that Lacks a Protruding Loop

T. Kepler, J. Mascola, J. Binley, 2017, Immunity.

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide

T. Kepler, H. Liao, J. Sodroski, 2017, Science Translational Medicine.

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

Tongqing Zhou, Gwo-Yu Chuang, M. Gordon Joyce, 2017, Journal of Virology.

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

J. Mascola, G. Chuang, I. Georgiev, 2019, Pathogens & immunity.

Stable inhibition of mmu-miR-466h-5p improves apoptosis resistance and protein production in CHO cells.

J. Shiloach, M. Betenbaugh, A. Druz, 2013, Metabolic engineering.

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

Cinque S. Soto, U. Baxa, J. Mascola, 2016, Nature Structural &Molecular Biology.

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

Cinque S. Soto, U. Baxa, J. Mascola, 2015, PloS one.

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env

U. Baxa, J. Mascola, G. Chuang, 2015, Journal of Virology.

Transplanting Supersites of HIV-1 Vulnerability

Cinque S. Soto, D. Burton, M. Connors, 2014, PloS one.

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

J. Mascola, N. Doria-Rose, P. Kwong, 2015, Journal of Virology.

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains.

U. Baxa, J. Mascola, G. Chuang, 2017, Cell reports.

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Alon Herschhorn, J. Sodroski, J. Mascola, 2019, Nature Communications.

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

U. Baxa, J. Mascola, I. Georgiev, 2018, ACS infectious diseases.

HIV-1 V 1 V 2 antibody with exceptional potency 5 6

Chaim A. Schramm, B. Haynes, G. Chuang, 2015 .

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.

J. Mascola, G. Chuang, M. Sastry, 2018 .

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

James B. Munro, Daniel S. Terry, Cinque S. Soto, 2015, Nature Structural &Molecular Biology.

Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo

Kyle E. Roberts, Cinque S. Soto, B. Donald, 2014, Journal of Virology.