K. Cerosaletti

发表

Ultra-sensitive detection of rare T cell clones.

C. Desmarais, C. Carlson, H. Robins, 2012, Journal of immunological methods.

A Novel Approach to Tracking Antigen-Experienced CD4 T Cells into Functional Compartments via Tandem Deep and Shallow TCR Clonotyping

Chester Ni, M. Peakman, K. Cerosaletti, 2013, The Journal of Immunology.

Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome

Matthias Platzer, Karl Sperling, André Reis, 1998, Cell.

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency.

P. Jeggo, A. Gennery, K. Cerosaletti, 2001, Molecular cell.

ATR‐dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

P. Jeggo, K. Cerosaletti, M. O’Driscoll, 2006, EMBO Journal.

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Robin J. Leach, Paul S. Meltzer, Jean Weissenbach, 1993, Cell.

Nibrin Forkhead-associated Domain and Breast Cancer C-terminal Domain Are Both Required for Nuclear Focus Formation and Phosphorylation*

K. Cerosaletti, P. Concannon, 2003, Journal of Biological Chemistry.

Anya Schneider Mediated Signaling − Involves IL-6 regsResistance to Adaptive T In Active Relapsing-Remitting Multiple Sclerosis , Effector T Cell

Chester Ni, K. Cerosaletti, J. Buckner, 2013 .

In Active Relapsing-Remitting Multiple Sclerosis, Effector T Cell Resistance to Adaptive Tregs Involves IL-6–Mediated Signaling

Chester Ni, K. Cerosaletti, J. Buckner, 2013, Science Translational Medicine.

A novel mutation in a family with DNA ligase IV deficiency syndrome

K. Cerosaletti, S. Unal, M. Çetin, 2009, Pediatric blood & cancer.

Functional delivery of large genomic DNA to human cells with a peptide‐lipid vector

Robert E. White, M. James, K. Cerosaletti, 2003, The journal of gene medicine.

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances

K. Cerosaletti, K. Herold, M. Nakayama, 2019, Diabetes.

NBN Phosphorylation regulates the accumulation of MRN and ATM at sites of DNA Double-Strand Breaks

K. Cerosaletti, P. Concannon, Jie Wen, 2012, Oncogene.

Class I Antigen Expression in Line 1 Cells: Molecular Biology and Immunological Effects

L. Harwell, K. Cerosaletti, D. Bahler, 1987 .

Attenuated IL-2R signaling in CD4 memory T cells of T1D subjects is intrinsic and dependent on activation state.

M. Gavin, K. Cerosaletti, J. Buckner, 2017, Clinical immunology.

The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes.

K. Cerosaletti, B. Greenberg, R. Fournier, 1995, Genomics.

and Shallow TCR Clonotyping Functional Compartments via Tandem Deep Antigen-Experienced CD4 T Cells into A Novel Approach to Tracking

Chester Ni, M. Peakman, K. Cerosaletti, 2013 .

Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes

Jeremy R. B. Newman, P. Concannon, K. Cerosaletti, 2022, bioRxiv.

IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation

P. Linsley, K. Cerosaletti, J. Buckner, 2022, Frontiers in Immunology.

Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression

D. Rawlings, K. Cerosaletti, T. Habib, 2019, Diabetes.

In‐vivo assessment of T cell kinetics in individuals at risk for type 1 diabetes

K. Cerosaletti, C. Greenbaum, C. Speake, 2020, Clinical and experimental immunology.

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

P. Jeggo, K. Cerosaletti, M. O’Driscoll, 2008, Human molecular genetics.

Molecular analysis of deficient class I H-2 antigen expression by mouse lung carcinoma cells.

K. Cerosaletti, D. Bahler, J. Frelinger, 1988, Journal of immunology.

Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation.

K. Cerosaletti, M. Zdzienicka, P. Concannon, 2000, Mutagenesis.

Mutations and molecular variants of the NBS1 gene in non‐Hodgkin lymphoma

V. A. Morrison, K. Cerosaletti, D. Willerford, 2002, Genes, chromosomes & cancer.

Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models

P. Linsley, D. Liggitt, D. Rawlings, 2022, Science Translational Medicine.

Endomembrane targeting of human OAS1 p46 augments antiviral activity

Vineet D. Menachery, J. Baillie, K. Cerosaletti, 2021, bioRxiv.

Comparison of latex agglutination and counterimmunoelectrophoresis for the detection of pneumococcal antigen in elderly pneumonia patients

K. Cerosaletti, M. Roghmann, D. Bentley, 1985, Journal of clinical microbiology.

Conserved interferon signature between adult and pediatric eosinophilic esophagitis

S. Ziegler, K. Cerosaletti, J. Spergel, 2021 .

Active Role for Nibrin in the Kinetics of Atm Activation

K. Cerosaletti, P. Concannon, Jocyndra A. Wright, 2006, Molecular and Cellular Biology.

Independent Roles for Nibrin and Mre11-Rad50 in the Activation and Function of Atm*

K. Cerosaletti, P. Concannon, 2004, Journal of Biological Chemistry.

Identification of the human beta A2 crystallin gene (CRYBA2): localization of the gene on human chromosome 2 and of the homologous gene on mouse chromosome 1.

M. Rocchi, R. Sinke, N. Copeland, 1995, Genomics.

A patient with mutations in DNA Ligase IV: Clinical features and overlap with Nijmegen breakage syndrome

K. Cerosaletti, T. Ben-Omran, M. Nezarati, 2005, American journal of medical genetics. Part A.

Nijmegen breakage syndrome in a Dutch patient not resulting from a defect in NBS1

F. Gabreëls, K. Cerosaletti, M. Ligtenberg, 2001, Journal of medical genetics.

Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

K. Cerosaletti, Zhon-Yin Zhang, J. Buckner, 2009, Diabetes.

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes

Darrell M. Wilson, J. Gaglia, P. Raskin, 2021, JCI insight.

Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression

K. Cerosaletti, E. Whalen, J. Buckner, 2016, Science Translational Medicine.

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

E. Bonifacio, S. Buus, R. Scharfmann, 2018, Science Immunology.

Multiple Autoimmune-Associated Variants Confer Decreased IL-2R Signaling in CD4+CD25hi T Cells of Type 1 Diabetic and Multiple Sclerosis Patients

Elizabeth Whalen, Ian Frank, I. Frank, 2013, PloS one.

An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4+ T cells

K. Cerosaletti, J. Buckner, Shan Wei, 2010, Genes and Immunity.

Nijmegen breakage syndrome: clinical characteristics and mutation analysis in eight unrelated Russian families.

K. Cerosaletti, O. Evgrafov, R. Gatti, 2002, The Journal of pediatrics.

ATM-dependent phosphorylation of nibrin in response to radiation exposure

M. Gatei, K. Khanna, K. Cerosaletti, 2000, Nature Genetics.

Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes

James A. Eddy, P. Linsley, R. Gottardo, 2017, The Journal of Immunology.

Renegade homeostatic cytokine responses in T1D: drivers of regulatory/effector T cell imbalance.

K. Cerosaletti, Shipra Gupta, S. A. Long, 2014, Clinical immunology.

Fine localization of the Nijmegen breakage syndrome gene to 8q21: evidence for a common founder haplotype.

M. Boehnke, A. Elliott, H. Stringham, 1998, American journal of human genetics.

The A946T variant IFIH1 RNA sensor mediates an interferon program that limits viral infection but increases the risk for autoimmunity

D. Liggitt, P. Concannon, D. Rawlings, 2017, Nature Immunology.

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

L. Wiesmüller, M. Gatei, K. Khanna, 2015, Nucleic acids research.

High TLR7 Expression Drives the Expansion of CD19+CD24hiCD38hi Transitional B Cells and Autoantibody Production in SLE Patients

Quanzhen Li, K. Cerosaletti, K. Elkon, 2019, Front. Immunol..

Nuclear Export of NBN Is Required for Normal Cellular Responses to Radiation

K. Cerosaletti, Jennifer Phillips, Christine S. Vissinga, 2008, Molecular and Cellular Biology.

The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets

D. Rawlings, M. Oukka, K. Cerosaletti, 2019, Front. Immunol..

Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes

Kaitlin J. Flynn, P. Linsley, V. Gersuk, 2021, JCI insight.

Protein Tyrosine Phosphatases and Type 1 Diabetes : Genetic and Functional Implications of PTPN 2 and PTPN 22

K. Cerosaletti, J. Buckner, 2013 .

Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22.

K. Cerosaletti, J. Buckner, 2012, The review of diabetic studies : RDS.

Distinct Functional Domains of Nibrin Mediate Mre11 Binding, Focus Formation, and Nuclear Localization

K. Cerosaletti, P. Concannon, A. Desai-Mehta, 2001, Molecular and Cellular Biology.

HLA alleles and sustained peanut consumption promote IgG4 responses in subjects protected from peanut allergy

I. Ruczinski, K. Barnes, R. Mathias, 2022, The Journal of clinical investigation.

The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.

Veronika A. Glukhova, K. Cerosaletti, R. James, 2016, Clinical immunology.

Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes

K. Cerosaletti, S. Flanagan, J. Buckner, 2019, Current Diabetes Reports.

Cloning mammary cell cDNAs from 17q12-q23 using interspecific somatic cell hybrids and subtractive hybridization.

M. Shapero, K. Cerosaletti, R. Fournier, 1995, Genomics.

Single Nucleotide Variant in FAS Associates With Organ Failure and Soluble Fas Cell Surface Death Receptor in Critical Illness

C. Robinson-Cohen, D. Christiani, M. Wurfel, 2021, Critical care medicine.

The MALT1 locus and peanut avoidance in the risk for peanut allergy.

I. Ruczinski, K. Barnes, R. Mathias, 2019, The Journal of allergy and clinical immunology.

The Autoimmune Risk R262W Variant of the Adaptor SH2B3 Improves Survival in Sepsis.

M. Wurfel, D. Liggitt, D. Rawlings, 2021, Journal of Immunology.

Medulloblastoma with adverse reaction to radiation therapy in nijmegen breakage syndrome.

K. Cerosaletti, R. Gatti, S. Bakhshi, 2003, Journal of pediatric hematology/oncology.

PTPN22 R620W gene editing in T cells enhances low-avidity TCR responses

P. Linsley, D. Rawlings, K. Cerosaletti, 2022, bioRxiv.

Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis

S. Ziegler, K. Cerosaletti, Alex Hu, 2021, The Journal of Immunology.

Self-reactive germline-like TCR alpha chains shared between blood and pancreas

K. Cerosaletti, C. Speake, Elisavet Serti, 2023, Research Square.

Islet-autoreactive CD4+ T cells are linked with response to alefacept in type 1 diabetes

V. Gersuk, K. Cerosaletti, C. Speake, 2023, JCI insight.

Class‐I MHC expression in the mouse lung carcinoma, line 1: A model for class‐I inducible tumors

K. Cerosaletti, A. McAdam, J. Frelinger, 1991, International journal of cancer. Supplement = Journal international du cancer. Supplement.

A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab

K. Cerosaletti, K. Herold, G. Nepom, 2023, Diabetologia.