N. DeLuca

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Herpes simplex virus type 1 VP26 is not essential for replication in cell culture but influences production of infectious virus in the nervous system of infected mice.

P. Desai, S. Person, N. DeLuca, 1998, Virology.

The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes

Albrecht, S. Hammer, N. DeLuca, 1989, Journal of virology.

Herpes Simplex Virus 1 Has Multiple Mechanisms for Blocking Virus-Induced Interferon Production

N. DeLuca, D. Knipe, G. T. Melroe, 2004, Journal of Virology.

Genetic engineering of a modified herpes simplex virus 1 vaccine vector.

N. DeLuca, Xueqiao Liu, D. Knipe, 2009, Vaccine.

Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced delivery.

W. Fellows-Mayle, C. Hadjipanayis, N. DeLuca, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Temporal Viral Genome-Protein Interactions Define Distinct Stages of Productive Herpesviral Infection

N. DeLuca, Jill A. Dembowski, 2018, bioRxiv.

Oligomerization of ICP4 and Rearrangement of Heat Shock Proteins May Be Important for Herpes Simplex Virus Type 1 Prereplicative Site Formation

N. DeLuca, S. Weller, Dianna E. Wilkinson, 2008, Journal of Virology.

Binding of ICP4, TATA-Binding Protein, and RNA Polymerase II to Herpes Simplex Virus Type 1 Immediate-Early, Early, and Late Promoters in Virus-Infected Cells

N. DeLuca, P. Sampath, 2007, Journal of Virology.

Persistence and Expression of the Herpes Simplex Virus Genome in the Absence of Immediate-Early Proteins

N. DeLuca, L. A. Samaniego, Lisa Neiderhiser, 1998, Journal of Virology.

ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB

C. Smith, N. DeLuca, B. Gu, 1993, Journal of virology.

Linker-insertion nonsense and restriction-site deletion mutations of the gB glycoprotein gene of herpes simplex virus type 1

S. Person, N. DeLuca, S. C. Warner, 1987, Journal of virology.

Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

N. DeLuca, P. Schaffer, 1985, Molecular and cellular biology.

Design and application of HSV vectors for neuroprotection

N. DeLuca, J. Glorioso, D. Wolfe, 2000, Gene Therapy.

Repression of activator-mediated transcription by herpes simplex virus ICP4 via a mechanism involving interactions with the basal transcription factors TATA-binding protein and TFIIB

N. DeLuca, B. Gu, R. Kuddus, 1995, Molecular and cellular biology.

Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22

Simon C Watkins, N. DeLuca, P. Schaffer, 1996, Journal of virology.

The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27

N. DeLuca, L. A. Samaniego, N. Wu, 1997, Journal of virology.

A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts

N. DeLuca, Jill A. Dembowski, Hannah L. Fox, 2017, mBio.

Perturbation of Cell Cycle Progression and Cellular Gene Expression as a Function of Herpes Simplex Virus ICP0

N. DeLuca, W. Hobbs, 1999, Journal of Virology.

The herpes simplex virus-1 ( HSV-1 ) – infected cell protein 0 ( ICP 0

W. Fellows-Mayle, C. Hadjipanayis, N. DeLuca, 2022 .

Inhibition of DNA repair by a herpes simplex virus vector enhances the radiosensitivity of human glioblastoma cells.

C. Hadjipanayis, N. DeLuca, 2005, Cancer research.

Combined cytotoxic activity of an infectious, but non‐replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells

B. Schmidt, N. DeLuca, D. Knipe, 2015, Immunology.

Stabilized Binding of TBP to the TATA Box of Herpes Simplex Virus Type 1 Early (tk) and Late (gC) Promoters by TFIIA and ICP4

N. DeLuca, S. Zabierowski, 2008, Journal of Virology.

Differential Cellular Requirements for Activation of Herpes Simplex Virus Type 1 Early (tk) and Late (gC) Promoters by ICP4

N. DeLuca, S. Zabierowski, 2004, Journal of Virology.

Genome replication affects transcription factor binding mediating the cascade of herpes simplex virus transcription

N. DeLuca, Sarah E. Dremel, 2019, Proceedings of the National Academy of Sciences.

Substitution of a TATA box from a herpes simplex virus late gene in the viral thymidine kinase promoter alters ICP4 inducibility but not temporal expression

N. DeLuca, A. Imbalzano, 1992, Journal of virology.

Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression

N. DeLuca, P. Schaffer, M. Courtney, 1984, Journal of virology.

Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4

N. DeLuca, A. L. Webb, L. A. Samaniego, 1995, Journal of virology.

Relationship of herpes simplex virus genome configuration to productive and persistent infections

N. DeLuca, S. Jackson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Temperature-Dependent Conformational Changes in Herpes Simplex Virus ICP4 That Affect Transcription Activation

N. DeLuca, P. Compel, 2003, Journal of Virology.

Temperature-Dependent Conformational Changes in Herpes Simplex Virus ICP 4 That Affect Transcription Activation Peter Compel

N. DeLuca, 2003 .

DNA-Dependent Oligomerization of Herpes Simplex Virus Type 1 Regulatory Protein ICP4

N. DeLuca, R. Kuddus, 2007, Journal of Virology.

Interferon Production Mechanisms for Blocking Virus-Induced Herpes Simplex Virus 1 Has Multiple

N. DeLuca, D. Knipe, G. T. Melroe, 2004 .

Separation of primary structural components conferring autoregulation, transactivation, and DNA-binding properties to the herpes simplex virus transcriptional regulatory protein ICP4

N. DeLuca, A. Imbalzano, A. Shepard, 1989, Journal of virology.

Characteristics of a new bacteriophage, Psp231a, infecting Pseudomonas phaseolicola HB10Y

N. DeLuca, W. Taylor, W. Snipes, 1980, Journal of virology.

The effect of ammonium chloride and tunicamycin on the glycoprotein content and infectivity of herpes simplex virus type 1.

S. Person, N. DeLuca, K. Kousoulas, 1983, Virology.

Relaxed Repression of Herpes Simplex Virus Type 1 Genomes in Murine Trigeminal Neurons

N. DeLuca, Colton A. Smith, T. Terry-Allison, 2007, Journal of Virology.

Safety and biodistribution studies of an HSV multigene vector following intracranial delivery to non-human primates

D. Kondziolka, E. Kanal, A. Niranjan, 2004, Gene Therapy.

Phosphorylation of Transcription Factor Sp1 during Herpes Simplex Virus Type 1 Infection

N. DeLuca, Dool-Bboon Kim, 2002, Journal of Virology.

HSV as a gene transfer vector for the nervous system

N. DeLuca, J. Glorioso, W. Goins, 1995, Molecular biotechnology.

Herpes Simplex Virus as a Gene-Delivery Vector for the Central Nervous System

N. DeLuca, J. Glorioso, W. Goins, 1995 .

Gene transfer to brain using herpes simplex virus vectors

N. DeLuca, J. Glorioso, W. Goins, 1994, Annals of neurology.

Efficient Activation of Viral Genomes by Levels of Herpes Simplex Virus ICP0 Insufficient To Affect Cellular Gene Expression or Cell Survival

D. Brough, N. DeLuca, I. Kovesdi, 2001, Journal of Virology.

Oligoadenylate‐Synthetase‐Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production

N. DeLuca, S. Thorne, P. Sampath, 2019, Immunity.

Nucleotide sequences of herpes simplex virus type 1 (HSV-1) affecting virus entry, cell fusion, and production of glycoprotein gb (VP7).

S. Person, N. DeLuca, W. Snipes, 1982, Virology.

Requirement of the N-Terminal Activation Domain of Herpes Simplex Virus ICP4 for Viral Gene Expression

N. DeLuca, Avraham Bayer, L. M. Wagner, 2012, Journal of Virology.

The High Mobility Group Protein 1 Is a Coactivator of Herpes Simplex Virus ICP4 In Vitro

N. DeLuca, M. Carrozza, 1998, Journal of Virology.

Vitro Coactivator of Herpes Simplex Virus ICP 4 In The High Mobility Group Protein 1 Is a

N. DeLuca, M. Carrozza, 1998 .

Production of immunogenic West Nile virus-like particles using a herpes simplex virus 1 recombinant vector.

S. Whelan, N. DeLuca, D. Knipe, 2016, Virology.

Development and application of herpes simplex virus vectors for human gene therapy.

N. DeLuca, J. Glorioso, D. Fink, 1995, Annual review of microbiology.

Herpes simplex virus for gene delivery to neurons.

X. Breakefield, N. DeLuca, DeLuca Na, 1991, The New biologist.

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

N. DeLuca, P. Schaffer, A. M. McCarthy, 1985, Journal of virology.

Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.

R. Martuza, X. Breakefield, N. DeLuca, 1990, The New biologist.

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides.

N. DeLuca, P. Schaffer, N. DeLuca, 1987, Nucleic acids research.

Replication-Coupled Recruitment of Viral and Cellular Factors to Herpes Simplex Virus Type 1 Replication Forks for the Maintenance and Expression of Viral Genomes

N. DeLuca, Jill A. Dembowski, Jill A Dembowski, 2017, PLoS pathogens.

Treatment of rat gliosarcoma brain tumors by HSV-based multigene therapy combined with radiosurgery.

Ajay Niranjan, L Dade Lunsford, Masakazu Tamura, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Activation of human immunodeficiency virus by herpes simplex virus.

S. Hammer, N. DeLuca, P. Schaffer, 1992, The Journal of infectious diseases.

Role of Protein Kinase A and the Serine-Rich Region of Herpes Simplex Virus Type 1 ICP 4 in Viral Replication

N. DeLuca, D. Knipe, K. Xia, 2005 .

The Initiator Element in a Herpes Simplex Virus Type 1 Late-Gene Promoter Enhances Activation by ICP4, Resulting in Abundant Late-Gene Expression

N. DeLuca, S. Zabierowski, Neal A. DeLuca, 2002, Journal of Virology.

Role of protein kinase A and the serine-rich region of herpes simplex virus type 1 ICP4 in viral replication

N. DeLuca, D. Knipe, K. Xia, 1996, Journal of virology.

Relationship between TATA-binding protein and herpes simplex virus type 1 ICP4 DNA-binding sites in complex formation and repression of transcription

N. DeLuca, B. Gu, R. Kuddus, 1995, Journal of virology.

Transdominant inhibition of herpes simplex virus growth in transgenic mice.

C. Smith, N. DeLuca, 1992, Virology.

Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene

N. DeLuca, A. Imbalzano, A. Shepard, 1990, Journal of virology.

Intragenic complementation among partial peptides of herpes simplex virus regulatory protein ICP4

N. DeLuca, A. Shepard, N. DeLuca, 1989, Journal of virology.

History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.

Ruchi M. Newman, A. Griffiths, N. DeLuca, 2016, Virology.

Herpes Simplex Virus 1 ICP4 Forms Complexes with TFIID and Mediator in Virus-Infected Cells

N. DeLuca, Jonathan T Lester, 2011, Journal of Virology.

Mutations in herpes simplex virus type 1 genes encoding VP5 and VP23 abrogate capsid formation and cleavage of replicated DNA

P. Desai, S. Person, N. DeLuca, 1993, Journal of virology.

Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene

N. DeLuca, D. Coen, A. Imbalzano, 1991, Journal of virology.

Genome locations of temperature-sensitive mutants in glycoprotein gB of herpes simplex virus type 1.

S. Person, N. DeLuca, W. Snipes, 1984, Virology.

Interaction of the viral activator protein ICP4 with TFIID through TAF250

N. DeLuca, M. Carrozza, 1996, Molecular and cellular biology.

Development of Herpes Simplex Virus Vectors for Gene Transfer to the Central Nervous System

N. DeLuca, J. Glorioso, W. Goins, 1994 .

Temporal Viral Genome-Protein Interactions Define Distinct Stages of Productive Herpesviral Infection

N. DeLuca, Jill A. Dembowski, 2018, mBio.

Selective Recruitment of Nuclear Factors to Productively Replicating Herpes Simplex Virus Genomes

N. DeLuca, Jill A. Dembowski, Neal A. DeLuca, 2015, PLoS pathogens.

Temporal Association of Herpes Simplex Virus ICP4 with Cellular Complexes Functioning at Multiple Steps in PolII Transcription

N. DeLuca, L. M. Wagner, 2013, PloS one.

Activities of ICP0 Involved in the Reversal of Silencing of Quiescent Herpes Simplex Virus 1

N. DeLuca, Daniel J. Ranayhossaini, Michael W. Ferenczy, 2011, Journal of Virology.

Herpes Simplex Virus Type 1 ICP4 Promotes Transcription Preinitiation Complex Formation by Enhancing the Binding of TFIID to DNA

N. DeLuca, B. Grondin, 2000, Journal of Virology.

Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4

N. DeLuca, D. Knipe, K. Xia, 1996, Journal of virology.

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4

N. DeLuca, P. Schaffer, 1988, Journal of virology.

Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells

N. DeLuca, P. Schaffer, Z. Zhu, 1996, Journal of virology.

repression of transcription . DNA-binding sites in complex formation and and herpes simplex virus type 1 ICP 4 Relationship between TATA-binding protein

N. DeLuca, B. Gu, R. Kuddus, 1995 .

Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4

N. DeLuca, B. Gu, 1994, Journal of virology.

Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoter.

C. Smith, N. DeLuca, B. Gu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4

N. DeLuca, A. Shepard, 1991, Journal of virology.

The N Terminus and C Terminus of Herpes Simplex Virus 1 ICP4 Cooperate To Activate Viral Gene Expression

N. DeLuca, L. M. Wagner, Jonathan T Lester, 2012, Journal of Virology.

Herpes Simplex Virus 1 ICP 4 Forms Complexes with TFIID and Mediator in Virus-Infected Cells

N. DeLuca, Jonathan T Lester, 2011 .

Induction of transcription by a viral regulatory protein depends on the relative strengths of functional TATA boxes

N. DeLuca, D. Coen, W. Cook, 1995, Molecular and cellular biology.

Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector.

T. Ndung’u, N. DeLuca, D. Knipe, 2007, Virology.

A second-site revertant of a defective herpes simplex virus ICP4 protein with restored regulatory activities and impaired DNA-binding properties

N. DeLuca, A. Shepard, 1991, Journal of virology.

Requirements forActivation oftheHerpesSimplex Virus Glycoprotein C Promoter InVitrobytheViral Regulatory Protein ICP4

N. DeLuca, B. Gu, 1994 .

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

N. DeLuca, D. Knipe, M. H. Orzalli, 2012, Proceedings of the National Academy of Sciences.

Nucleotide sequence of a region of the herpes simplex virus type 1 gB glycoprotein gene: mutations affecting rate of virus entry and cell fusion.

S. Person, N. DeLuca, B. A. Fox, 1984, Virology.

Antiviral Properties of the LSD1 Inhibitor SP-2509

N. DeLuca, Jill A. Dembowski, Jessica E. Packard, 2020, Journal of Virology.

Herpes simplex viral nucleoprotein creates a competitive transcriptional environment facilitating robust viral transcription and host shut off

N. DeLuca, Sarah E. Dremel, 2019, bioRxiv.

Nucleotide sequence specifying the glycoprotein gene, gB, of herpes simplex virus type 1.

S. Person, N. DeLuca, B. A. Fox, 1984, Virology.

Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA

B. Schmidt, N. DeLuca, D. Knipe, 2019, Front. Immunol..

Manipulation of RNA polymerase III by Herpes Simplex Virus-1

N. DeLuca, B. Glaunsinger, Jessica M. Tucker, 2021, Nature Communications.

Expression of Herpes Simplex Virus ICP0 Inhibits the Induction of Interferon-Stimulated Genes by Viral Infection

N. DeLuca, B. Manning, W. Hobbs, 2002, Journal of Virology.

Epigenetic Modulation of Gene Expression from Quiescent Herpes Simplex Virus Genomes

N. DeLuca, Michael W. Ferenczy, 2009, Journal of Virology.

Immunogenicity of herpes simplex virus type 1 mutants containing deletions in one or more alpha-genes: ICP4, ICP27, ICP22, and ICP0.

N. DeLuca, S. Tevethia, M. Brehm, 1999, Virology.

Transcription of the Herpes Simplex Virus 1 Genome during Productive and Quiescent Infection of Neuronal and Nonneuronal Cells

N. DeLuca, Neal A. DeLuca, Justine M. Harkness, 2014, Journal of Virology.

Reversal of Heterochromatic Silencing of Quiescent Herpes Simplex Virus Type 1 by ICP0

N. DeLuca, Michael W. Ferenczy, 2010, Journal of Virology.

The role of ICP4 repressor activity in temporal expression of the IE-3 and latency-associated transcript promoters during HSV-1 infection.

N. DeLuca, A. Imbalzano, B. Gu, 1994, Virology.

Gene transfer to neurons using herpes simplex virus-based vectors.

N. DeLuca, J. Glorioso, W. Goins, 1996, Annual review of neuroscience.

The Polyserine Tract of Herpes Simplex Virus ICP4 Is Required for Normal Viral Gene Expression and Growth in Murine Trigeminal Ganglia

N. DeLuca, P. Bates, 1998, Journal of Virology.

Studies with a Hydrophobic, Spin-Labeled Virucidal Agent

N. DeLuca, A. Keith, W. Snipes, 1980, Antimicrobial Agents and Chemotherapy.

trans-dominant inhibition of herpes simplex virus transcriptional regulatory protein ICP4 by heterodimer formation

N. DeLuca, P. Tolentino, A. Shepard, 1990, Journal of virology.

Herpes simplex virus vectors.

N. DeLuca, J. Glorioso, D. Fink, 1995, Molecular and cell biology of human diseases series.

Herpes simplex virus vectors and gene transfer to brain.

N. DeLuca, J. Glorioso, W. Goins, 1994, Developments in biological standardization.

Localization and Membrane Topology of Coronavirus Nonstructural Protein 4: Involvement of the Early Secretory Pathway in Replication

D. Hazuda, B. Cullen, N. DeLuca, 2007, Journal of Virology.

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

N. DeLuca, D. Knipe, M. H. Orzalli, 2012, Proceedings of the National Academy of Sciences.

Transcription of the Herpes Simplex Virus 1 Genome during Productive and Quiescent Infection of Neuronal and Nonneuronal Cells

N. DeLuca, M. Kader, J. Harkness, 2014, Journal of Virology.