Dennis Brown

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Massively Parallel Sequencing of Human Urinary Exosome/Microvesicle RNA Reveals a Predominance of Non-Coding RNA

A. Sivachenko, J. Levin, X. Adiconis, 2014, PloS one.

Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.

M. Mclaughlin, D. Ausiello, Dennis Brown, 2013, American journal of physiology. Renal physiology.

The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.

Dennis Brown, H. Lu, R. Bouley, 2008, American journal of physiology. Renal physiology.

Phosphorylation events and the modulation of aquaporin 2 cell surface expression

Dennis Brown, R. Bouley, P. Nunes, 2008, Current opinion in nephrology and hypertension.

Characterization and Correction of Olfactory Deficits in Kidney Disease.

E. Holbrook, Dennis Brown, T. Paunescu, 2017, Journal of the American Society of Nephrology : JASN.

Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging

R. Weissleder, Claudio Vinegoni, Dennis Brown, 2016, Nature Communications.

Characterizing the interactions of organic nanoparticles with renal epithelial cells in vivo.

R. Weissleder, Dennis Brown, A. Nair, 2015, ACS nano.

Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes.

D. Salant, Dennis Brown, H. Kawachi, 1997, AJP - Renal Physiology.

Hypertonicity Is Involved in Redirecting the Aquaporin-2 Water Channel into the Basolateral, Instead of the Apical, Plasma Membrane of Renal Epithelial Cells*

B. W. van Balkom, Dennis Brown, P. Deen, 2003, The Journal of Biological Chemistry.

Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus.

Dennis Brown, H. Lu, R. Bouley, 2008, Seminars in nephrology.

Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells.

Dennis Brown, K. Hallows, N. Pastor-Soler, 2008, American journal of physiology. Cell physiology.

Vasopressin stimulates formation of coated pits in rat kidney collecting ducts

L. Orci, Dennis Brown, 1983, Nature.

Aquaporin-2 localization in clathrin-coated pits: inhibition of endocytosis by dominant-negative dynamin.

M. Mclaughlin, Dennis Brown, R. Bouley, 2002, American journal of physiology. Renal physiology.

Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2.

M. Mclaughlin, Dennis Brown, H. Lu, 2004, American journal of physiology. Renal physiology.

Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra).

M. Mclaughlin, Dennis Brown, N. Pastor-Soler, 2005, American journal of physiology. Renal physiology.

Hydrocortisone modulates cholera toxin endocytosis by regulating immature enterocyte plasma membrane phospholipids.

Dennis Brown, A. Quaroni, Yuanwu Bao, 2008, Gastroenterology.

Unravelling purinergic regulation in the epididymis: activation of V‐ATPase‐dependent acidification by luminal ATP and adenosine

Dennis Brown, S. Breton, F. Gombar, 2019, The Journal of physiology.

Regulation of luminal acidification by the V-ATPase.

Dennis Brown, S. Breton, 2013, Physiology.

Role of purinergic signaling pathways in V-ATPase recruitment to apical membrane of acidifying epididymal clear cells.

Dennis Brown, C. Belleannée, N. Da Silva, 2010, American journal of physiology. Cell physiology.

Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells

Dennis Brown, R. Bouley, N. Yui, 2020, Cells.

cAMP stimulates apical V-ATPase accumulation, microvillar elongation, and proton extrusion in kidney collecting duct A-intercalated cells.

M. Mclaughlin, Dennis Brown, L. M. Russo, 2010, American journal of physiology. Renal physiology.

Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit.

M. Mckee, Dennis Brown, T. Paunescu, 2007, American journal of physiology. Cell physiology.

New insights into the regulation of V-ATPase-dependent proton secretion.

Dennis Brown, S. Breton, 2007, American journal of physiology. Renal physiology.

Localization of pH regulating proteins H+ATPase and Cl − HCO 3 −

Joe C. Adams, Dennis Brown, S. Alper, 1997, Hearing Research.

Cadmium Inhibits Vacuolar H+ATPase-Mediated Acidification in the Rat Epididymis1

Dennis Brown, Peter J. S. Smith, I. Sabolić, 2000, Biology of reproduction.

Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel.

Dennis Brown, H. Lu, R. Bouley, 2013, American journal of physiology. Cell physiology.

Visualizing microtubule-dependent vasopressin type 2 receptor trafficking using a new high-affinity fluorescent vasopressin ligand.

D. Ausiello, Dennis Brown, M. Webber, 2011, Endocrinology.

Regulation of the V-ATPase in kidney epithelial cells: dual role in acid–base homeostasis and vesicle trafficking

Dennis Brown, T. Paunescu, V. Marshansky, 2009, Journal of Experimental Biology.

The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease

Dennis Brown, A. Eaton, M. Merkulova, 2020, American journal of physiology. Cell physiology.

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

D. Ausiello, Dennis Brown, A. Wildeman, 2006, Nature Cell Biology.

Renal vacuolar H+-ATPase.

K. Finberg, Dennis Brown, C. Wagner, 2004, Physiological reviews.

A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule

Dennis Brown, T. Jentsch, N. Picard, 2012, EMBO molecular medicine.

NHE3 and NHERF are targeted to the basolateral membrane in proximal tubules of colchicine-treated rats.

Dennis Brown, I. Sabolić, D. Biemesderfer, 2002, Kidney international.

The ins and outs of aquaporin-2 trafficking.

Dennis Brown, 2003, American journal of physiology. Renal physiology.

Covalent Modulators of the Vacuolar ATPase.

B. Cravatt, Dennis Brown, Keriann M. Backus, 2017, Journal of the American Chemical Society.

Heat Shock Protein 70 Interacts with Aquaporin-2 and Regulates Its Trafficking*

M. Mckee, Dennis Brown, H. Lu, 2007, Journal of Biological Chemistry.

Expression of GTPase-deficient Giα2 Results in Translocation of Cytoplasmic RGS4 to the Plasma Membrane*

Dennis Brown, K. Blumer, K. Druey, 1998, The Journal of Biological Chemistry.

Postnatal Expression of Aquaporins in Epithelial Cells of the Rat Epididymis1

Dennis Brown, Valerie Beaulieu, C. Silberstein, 2006, Biology of reproduction.

An Extended Nomenclature for Mammalian V-ATPase Subunit Genes and Splice Variants

K. Miranda, Dennis Brown, F. Karet, 2010, PloS one.

ILK and cytoskeletal architecture: an important determinant of AQP2 recycling and subsequent entry into the exocytotic pathway.

Dennis Brown, H. Lu, Wei Li, 2016, American journal of physiology. Renal physiology.

Proteomic analysis of V-ATPase-rich cells harvested from the kidney and epididymis by fluorescence-activated cell sorting.

Dennis Brown, T. Pisitkun, M. Knepper, 2010, American journal of physiology. Cell physiology.

The B1-subunit of the H(+) ATPase is required for maximal urinary acidification.

G. Giebisch, R. Lifton, K. Finberg, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice.

M. Mckee, Dennis Brown, L. M. Russo, 2007, American journal of physiology. Renal physiology.

The absence of a clathrin adapter confers unique polarity essential to proximal tubule function.

Dennis Brown, E. Rodriguez-Boulan, R. Schreiner, 2010, Kidney international.

Exploring the role of galectin 3 in kidney function: a genetic approach.

N. Farman, Dennis Brown, M. Peuchmaur, 2006, Glycobiology.

Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.

D. Ausiello, Dennis Brown, H. Lu, 2007, American journal of physiology. Renal physiology.

Cellular mechanisms of aquaporin trafficking.

Dennis Brown, T. Katsura, Corinne E. Gustafson, 1998, American journal of physiology. Renal physiology.

Possible Localization in the Golgi Area

Dennis Brown, 2003 .

Localization of the high-affinity glutamate transporter EAAC1 in rat kidney.

M. Hediger, J. Rothstein, Dennis Brown, 1997, AJP - Renal Physiology.

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor.

Dennis Brown, L. M. Russo, Herbert Y. Lin, 2007, Diabetes.

Evidence for a Role of Transforming Growth Factor (TGF)-β1 in the Induction of Postglomerular Albuminuria in Diabetic Nephropathy

Dennis Brown, L. M. Russo, Herbert Y. Lin, 2007, Diabetes.

Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.

M. Mclaughlin, M. Mckee, Dennis Brown, 2013, American journal of physiology. Renal physiology.

Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS)

M. Mclaughlin, Dennis Brown, S. Alper, 1996, Histochemistry and Cell Biology.

Role of Megalin (gp330) in Transcytosis of Thyroglobulin by Thyroid Cells

A. Pinchera, L. Chiovato, Dennis Brown, 2000, The Journal of Biological Chemistry.

CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway

Dennis Brown, H. Chan, R. Diao, 2014, Journal of Cell Science.

NF-κB Modulates Aquaporin-2 Transcription in Renal Collecting Duct Principal Cells*

Dennis Brown, R. Bouley, U. Hasler, 2008, Journal of Biological Chemistry.

Role of VEGF-A in Vascularization of Pancreatic Islets

D. Melton, M. Mclaughlin, Dennis Brown, 2003, Current Biology.

Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.

M. Wax, Dennis Brown, R. Bouley, 2009, American journal of physiology. Renal physiology.

Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells.

Dennis Brown, N. Pastor-Soler, R. Bouley, 2004, American journal of physiology. Renal physiology.

Molecular Mechanisms of Vasopressin Action in the Kidney

K. Skorecki, L. Ercolani, D. Ausiello, 2011 .

Nonclathrin‐coated vesicles are involved in endocytosis in kidney collecting duct intercalated cells

L. Orci, Dennis Brown, P. Weyer, 1987, The Anatomical record.

Novel role of proton-secreting epithelial cells in sperm maturation and mucosal immunity

Dennis Brown, Diane E. Capen, A. Nair, 2019, Journal of Cell Science.

Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis.

Dennis Brown, T. Paunescu, L. Vedovelli, 2013, American journal of physiology. Cell physiology.

Transepithelial Projections from Basal Cells Are Luminal Sensors in Pseudostratified Epithelia

M. Mckee, Dennis Brown, Peter J. S. Smith, 2008, Cell.

A dense network of dendritic cells populates the murine epididymis.

M. Wildgruber, M. Pittet, Dennis Brown, 2011, Reproduction.

Altered V-ATPase expression in renal intercalated cells isolated from B1 subunit-deficient mice by fluorescence-activated cell sorting.

K. Finberg, Dennis Brown, C. Wagner, 2013, American journal of physiology. Renal physiology.

Aquaporin 2 promotes cell migration and epithelial morphogenesis.

J. Norman, Dennis Brown, H. Lu, 2012, Journal of the American Society of Nephrology : JASN.

New insights into the dynamic regulation of water and acid-base balance by renal epithelial cells.

Dennis Brown, T. Paunescu, R. Bouley, 2012, American journal of physiology. Cell physiology.

Deletion of hensin/DMBT1 blocks conversion of β- to α-intercalated cells and induces distal renal tubular acidosis

M. Mckee, Dennis Brown, F. Cheema, 2010, Proceedings of the National Academy of Sciences.

Methyl-β-cyclodextrin induces vasopressin-independent apical accumulation of aquaporin-2 in the isolated, perfused rat kidney

M. Mckee, Dennis Brown, L. M. Russo, 2006 .

Methyl-beta-cyclodextrin induces vasopressin-independent apical accumulation of aquaporin-2 in the isolated, perfused rat kidney.

M. Mckee, Dennis Brown, L. M. Russo, 2006, American journal of physiology. Renal physiology.

Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis.

M. Mckee, Dennis Brown, T. Paunescu, 2004, American journal of physiology. Cell physiology.

Renal principal cell-specific expression of green fluorescent protein in transgenic mice.

L. Zharkikh, Xiaohong Zhu, Dennis Brown, 2002, American journal of physiology. Renal physiology.

Erratum: In colchicine-treated rats, cellular distribution of AQP-1 in convoluted and straight proximal tubule segments is differently affected

Dennis Brown, S. Ivan, B. Mirela, 2000, Pflügers Archiv.

Vesicle Trafficking and Membrane Polarity in Epithelial Cells: Relationship to Intercalated Cell Function in Kidney Collecting Ducts

Dennis Brown, 1991 .

Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion

Dennis Brown, Diane E. Capen, J. Pluznick, 2020, Proceedings of the National Academy of Sciences.

Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport.

P. A. Friedman, Dennis Brown, Jianming Ba, 2003, American journal of physiology. Renal physiology.

Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells.

Dennis Brown, C. Hong, R. Bouley, 2010, Journal of the American Society of Nephrology : JASN.

Molecular mechanisms of acid-base sensing by the kidney.

Dennis Brown, C. Wagner, 2012, Journal of the American Society of Nephrology : JASN.

Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice

Dennis Brown, T. Paunescu, R. Bouley, 2019, PloS one.

Membrane Localization and Topology of Leukotriene C4 Synthase*

M. Mckee, Dennis Brown, P. Christmas, 2002, The Journal of Biological Chemistry.

Response to ‘Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique’

B. Molitoris, W. Comper, Dennis Brown, 2007 .

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.

Dennis Brown, R. Bouley, A. Nair, 2016, Journal of the American Society of Nephrology : JASN.

1 2 Aldosterone stimulates vacuolar H +-ATPase activity in 3 renal acid-secretory intercalated cells mainly via 4 a protein kinase C dependent pathway 5 6 7

Dennis Brown, C. Wagner, L. Vedovelli, 2011 .

Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ.

D. Ausiello, Dennis Brown, S. Bourgoin, 2004, American journal of physiology. Cell physiology.

Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion.

Dennis Brown, J. Bonventre, Richard Lee, 1997, American journal of physiology. Renal physiology.

Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.

F. Trepiccione, P. Houillier, Dennis Brown, 2016, Journal of the American Society of Nephrology : JASN.

Renal Epithelial Protein (Apx) Is an Actin Cytoskeleton-regulated Na+ Channel*

H. Cantiello, M. Mclaughlin, Dennis Brown, 1996, The Journal of Biological Chemistry.

Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cells.

M. Mclaughlin, M. Mckee, D. Ausiello, 2003, American journal of physiology. Cell physiology.

Role of NHERF1, Cystic Fibrosis Transmembrane Conductance Regulator, and cAMP in the Regulation of Aquaporin 9*

M. James, Dennis Brown, N. Pastor-Soler, 2008, Journal of Biological Chemistry.

The B1 Subunit of the H+ATPase Is a PDZ Domain-binding Protein

Dennis Brown, V. Ramesh, V. Marshansky, 2000, Journal of Biological Chemistry.

Intra-endosomal pH-sensitive Recruitment of the Arf-nucleotide Exchange Factor ARNO and Arf6 from Cytoplasm to Proximal Tubule Endosomes*

D. Ausiello, Dennis Brown, B. Maranda, 2001, The Journal of Biological Chemistry.

Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit.

Dennis Brown, R. Bouley, Pui W Cheung, 2020, Annual review of pharmacology and toxicology.

Missing Clathrin Adaptor Confers Unique Polarity Essential to Proximal Tubule Function

Dennis Brown, E. Rodriguez-Boulan, R. Schreiner, 2013 .

Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells.

Joshua N. Baker, P. Libby, R. Weissleder, 2015, Cell stem cell.

Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an Ae1 R607H Knockin Model.

F. Trepiccione, Dennis Brown, S. Alper, 2017, Journal of the American Society of Nephrology : JASN.

Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase Recycling*

Dennis Brown, N. Pastor-Soler, L. Levin, 2003, Journal of Biological Chemistry.

The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney.

Dennis Brown, R. Miller, R. Nelson, 2009, Kidney international.

Mitochondria-rich , H +-secreting epithelial cells 2347

Dennis Brown, S. Breton, 1996 .

REVIEW MITOCHONDRIA-RICH, PROTON-SECRETING EPITHELIAL CELLS

Dennis Brown, S. Breton, 1996 .

Regulation of luminal acidification in the male reproductive tract via cell–cell crosstalk

Dennis Brown, N. Da Silva, S. Breton, 2009, Journal of Experimental Biology.

A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse

G. Giebisch, Dennis Brown, C. Wagner, 2003, Pflügers Archiv.

Sex-dependent expression of water channel AQP1 along the rat nephron.

Dennis Brown, I. Vrhovac, D. Rogić, 2015, American journal of physiology. Renal physiology.

Sex and Gender Differences in Renal Physiology Sex-dependent expression of water channel AQP 1 along the rat nephron

Dennis Brown, I. Vrhovac, D. Rogić, 2015 .

Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells

Dennis Brown, H. Lu, T. Matsuzaki, 2012, PloS one.

AQP 2 is necessary for vasopressin-and forskolin-mediated filamentous actin depolymerization in renal epithelial cells

Dennis Brown, H. Lu, R. Bouley, 2012 .

AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells

Dennis Brown, H. Lu, R. Bouley, 2011, Biology Open.

Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase.

Dennis Brown, H. Lu, R. Bouley, 2011, American journal of physiology. Renal physiology.

Calcitonin has a vasopressin-like effect on aquaporin-2 trafficking and urinary concentration.

M. Mclaughlin, Dennis Brown, H. Lu, 2011, Journal of the American Society of Nephrology : JASN.

Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology

D. Ausiello, Dennis Brown, V. Marshansky, 2009, Traffic.

A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2.

M. Mckee, Dennis Brown, R. Bouley, 2008, American journal of physiology. Cell physiology.

regulation of AQP2 trafficking in renal epithelial cells

Dennis Brown, R. Bouley, T. Matsuzaki, 2008 .

Segmental and cellular expression of aquaporins in the male excurrent duct.

Dennis Brown, N. Da Silva, C. Pietrement, 2006, Biochimica et biophysica acta.

Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in ‘endocytosis‐resistant’ membrane domains after vasopressin treatment

D. Ausiello, Dennis Brown, L. M. Russo, 2006, Biology of the cell.

Antigen retrieval reveals widespread basolateral expression of syntaxin 3 in renal epithelia.

Dennis Brown, M. Knepper, S. Breton, 2002, American journal of physiology. Renal physiology.

expression of syntaxin 3 in renal epithelia Antigen retrieval reveals widespread basolateral

Dennis Brown, M. Knepper, S. Breton, 2016 .

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease.

Johan Skog, K. Miranda, M. Mckee, 2010, Kidney International.

The Discovery of Water Channels (Aquaporins)

Dennis Brown, 2017, Annals of Nutrition and Metabolism.

Characterization of the putative phosphorylation sites of the AQP2 C terminus and their role in AQP2 trafficking in LLC-PK1 cells.

Dennis Brown, William Jin, H. Lu, 2015, American journal of physiology. Renal physiology.

1 Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in 2 AQP2 trafficking in LLC-PK1 cells

Dennis Brown, William Jin, H. Lu, 2015 .

Heterogeneous localization of G protein α-subunits in rat kidney

Dennis Brown, J. Stow, I. Sabolić, 1991 .

Targeted deletion of the Ncoa7 gene results in incomplete distal renal tubular acidosis in mice.

P. Oliver, Dennis Brown, Diane E. Capen, 2018, American journal of physiology. Renal physiology.

The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells.

Dennis Brown, C. Wagner, Y. Colin, 2017, Kidney international.

Angiotensin II Stimulates H+-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts

G. Giebisch, Dennis Brown, N. Mohebbi, 2011, Cellular Physiology and Biochemistry.

The inhibition of nuclear DNA polymerizing activity by captan

Dennis Brown, R. Lewis, 1978 .

V-ATPase expression in the mouse olfactory epithelium.

Dennis Brown, T. Paunescu, R. Tyszkowski, 2008, American journal of physiology. Cell physiology.

Ezrin directly interacts with AQP2 and promotes its endocytosis

Dennis Brown, Kenji Tsuji, William Jin, 2017, Journal of Cell Science.

Acute Hypertonicity Alters Aquaporin-2 Trafficking and Induces a MAPK-dependent Accumulation at the Plasma Membrane of Renal Epithelial Cells*

Dennis Brown, R. Bouley, T. Matsuzaki, 2008, Journal of Biological Chemistry.

Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway.

D. Ausiello, Dennis Brown, R. Bouley, 2005, American journal of physiology. Cell physiology.

High Resolution Helium Ion Scanning Microscopy of the Rat Kidney

Dennis Brown, T. Paunescu, A. V. van Hoek, 2013, PloS one.

AQP2 is Necessary for Vasopressin Mediated Filamentous Actin Depolymerization in Renal Epithelial Cells

Dennis Brown, R. Bouley, N. Yui, 2011 .

Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells

M. Mclaughlin, Dennis Brown, L. M. Russo, 2010 .

Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cells.

M. Mckee, Dennis Brown, L. M. Russo, 2008, American journal of physiology. Renal physiology.

Acidification of the male reproductive tract by a proton pumping(H+)-ATPase

Dennis Brown, Peter J. S. Smith, S. Breton, 1996, Nature Medicine.

An H+-ATPase in opposite plasma membrane domains in kidney epithelial cell subpopulations

Dennis Brown, S. Gluck, Sheldon Hirscht, 1988, Nature.

Inhibition of non‐receptor tyrosine kinase Src induces phosphoserine 256‐independent aquaporin‐2 membrane accumulation

Dennis Brown, R. Bouley, Pui W Cheung, 2018, The Journal of physiology.

High-throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration.

S. Shaw, Dennis Brown, H. Lu, 2014, American journal of physiology. Cell physiology.

Aquaporin-2 inhibitors: fishing in the chemical pool.

Dennis Brown, H. Lu, H. Lu, 2013, Journal of the American Society of Nephrology : JASN.

Endosomes from kidney collecting tubule cells contain the vasopressin-sensitive water channel

A. Verkman, D. Ausiello, Dennis Brown, 1988, Nature.

The soluble transforming growth factor-beta receptor: advantages and applications.

Dennis Brown, L. M. Russo, Herbert Y. Lin, 2009, The international journal of biochemistry & cell biology.

Response to ‘On the origin of albuminuria’

B. Molitoris, W. Comper, Dennis Brown, 2007 .

Cellular distribution of the aquaporins: A family of water channel proteins

A. Verkman, Dennis Brown, T. Katsura, 1995, Histochemistry and Cell Biology.

Acidic and non-acidic endosomes in kidney epithelial cells: their role in cell-specific membrane recycling processes

Dennis Brown, I. Sabolić, 1994 .

collecting duct A-intercalated cells microvillar elongation, and proton extrusion in kidney cAMP stimulates apical V-ATPase accumulation,

M. Mclaughlin, Dennis Brown, L. M. Russo, 2011 .

Caveolin-2 Localizes to the Golgi Complex but Redistributes to Plasma Membrane, Caveolae, and Rafts when Co-expressed with Caveolin-1*

M. Lisanti, Dennis Brown, P. Scherer, 1999, The Journal of Biological Chemistry.

Is caveolin involved in normal proximal tubule function? Presence in model PT systems but absence in situ.

Dennis Brown, V. Marshansky, S. Breton, 2011, American journal of physiology. Renal physiology.

Structural Correlates of Transport in Distal Tubule and Collecting Duct Segments

J. Wade, Dennis Brown, B. Stanton, 2011 .

Distribution of the Vacuolar H+ATPase Along the Rat and Human Male Reproductive Tract1

Dennis Brown, I. Sabolić, S. Breton, 2001, Biology of reproduction.

High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa.

Dennis Brown, L. Lechner, T. Paunescu, 2014, Molecular human reproduction.

Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila.

Meredith E. Protas, M. Rämet, M. Mckee, 2003, Microbes and infection.

Animal plasma membrane energization by proton‐motive V‐ATPases

S. Grinstein, Dennis Brown, H. Wieczorek, 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.

Explorer Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones

R. Sharpe, Dennis Brown, N. Pastor-Soler, 2017 .

Aquaporin 9 Expression along the Male Reproductive Tract1

M. Mckee, Dennis Brown, N. Pastor-Soler, 2001, Biology of reproduction.

Expression of an AQP2 Cre recombinase transgene in kidney and male reproductive system of transgenic mice.

D. Ausiello, Dennis Brown, P. Stricklett, 1998, American journal of physiology. Cell physiology.

intestinal brush-border membranes

G. Burckhardt, Dennis Brown, I. Sabolić, 1995 .

Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM.

Dennis Brown, A. Yu, Valerie Beaulieu, 2003, American journal of physiology. Cell physiology.

Noncanonical Control of Vasopressin Receptor Type 2 Signaling by Retromer and Arrestin*

Dennis Brown, K. Hallows, J. King, 2013, The Journal of Biological Chemistry.

The Mercurial Insensitive Water Channel (AQP-4) Forms Orthogonal Arrays in Stably Transfected Chinese Hamster Ovary Cells (*)

A. Verkman, Dennis Brown, Baoxue Yang, 1996, The Journal of Biological Chemistry.

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

D. Clapham, R. Kalluri, Dennis Brown, 2005, Nature Genetics.

Region-specific transcriptomic and functional signatures of mononuclear phagocytes in the epididymis.

Dennis Brown, A. Nair, S. Breton, 2019, Molecular human reproduction.

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

Mark A. Knepper, Maurice B. Burg, Sylvie Breton, 2017, Proceedings of the National Academy of Sciences.

Expression of Aquaporin 9 in the Adult Rat Epididymal Epithelium Is Modulated by Androgens1

Dennis Brown, N. Pastor-Soler, A. V. van Hoek, 2002, Biology of reproduction.

Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium.

G. Gerken, M. Mckee, Dennis Brown, 2002, The American journal of pathology.

Plasticity of basal cells during postnatal development in the rat epididymis.

Dennis Brown, Eric Hill, S. Breton, 2013, Reproduction.

Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates

M. Manoharan, Dennis Brown, Svetlana Shulga-Morskaya, 2020, Nucleic acids research.

Ribosomal s6 kinase (RSK) is a mediator of aquaporin 2 S256 phosphorylation and membrane accumulation after EGFR inhibition with erlotinib

Dennis Brown, R. Bouley, Pui W Cheung, 2022, bioRxiv.

Postnatal development of H+ATPase (proton-pump)-rich cells in rat epididymis

Dennis Brown, I. Sabolić, S. Breton, 1999, Histochemistry and Cell Biology.

Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension.

G. Giebisch, R. Lifton, E. Boulpaep, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function

M. Mckee, Dennis Brown, T. Paunescu, 2012, PloS one.

Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia.

Dennis Brown, J. Bonventre, M. Abbate, 1999, American journal of physiology. Renal physiology.

Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney.

Dennis Brown, J. Bonventre, K. Matlin, 1998, American journal of physiology. Cell physiology.

Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling.

D. Ausiello, Dennis Brown, R. Bouley, 2008, Kidney international.

The B1 Subunit of the HATPase Is a PDZ Domain-binding Protein COLOCALIZATION WITH NHE-RF IN RENAL B-INTERCALATED CELLS*

Dennis Brown, V. Ramesh, V. Marshansky, 2000 .

Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.

D. Ausiello, Dennis Brown, V. Marshansky, 2011, American journal of physiology. Cell physiology.

TRPC 6 is a glomerular slit diaphragm-associated channel required for normal renal function

D. Clapham, R. Kalluri, Dennis Brown, 2005 .

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

Jae Wook Lee, Dennis Brown, T. Paunescu, 2017, Proceedings of the National Academy of Sciences.

Novel Proinflammatory Function of Renal Intercalated Cells

Dennis Brown, S. Breton, 2018, Annals of Nutrition and Metabolism.

Glycosylphosphatidylinositol‐anchored H‐2Db molecules are defective in antigen processing and presentation to cytotoxic T lymphocytes

R. Flavell, Dennis Brown, D. Roopenian, 1996, European journal of immunology.

Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells.

Dennis Brown, Diane E. Capen, A. Nair, 2017, Journal of the American Society of Nephrology : JASN.

Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor

K. Jacobson, M. Pittet, Dennis Brown, 2015, PloS one.

V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice.

Dennis Brown, T. Paunescu, R. Miller, 2005, American journal of physiology. Cell physiology.

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance.

K. H. Albrecht, N. LeBrasseur, Dan Yang, 2008, Cell metabolism.

Basolateral Distribution of Caveolin-1 in the Kidney: Absence from H+-ATPase-coated Endocytic Vesicles in Intercalated Cells

M. Mclaughlin, M. Lisanti, Dennis Brown, 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption.

Dennis Brown, R. Bouley, A. Nair, 2016, Journal of the American Society of Nephrology : JASN.

Cd-MT causes endocytosis of brush-border transporters in rat renal proximal tubules.

Dennis Brown, I. Sabolić, Marija Ljubojević, 2002, American journal of physiology. Renal physiology.

Immunolocalization of AE2 anion exchanger in rat kidney.

Dennis Brown, S. Alper, B. Shmukler, 1997, American journal of physiology. Renal physiology.

Effect of acidification on the location of H+-ATPase in cultured inner medullary collecting duct cells.

M. Mckee, Dennis Brown, E. Alexander, 1999, American journal of physiology. Cell physiology.

rapid communication Effect of acidification on the location of H 1 -ATPase in cultured inner medullary collecting duct cells

M. Mckee, Dennis Brown, E. Alexander, 1999 .

Aldosterone stimulates vacuolar H(+)-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway.

Dennis Brown, C. Wagner, T. Paunescu, 2011, American journal of physiology. Cell physiology.

Membrane macro- and microdomains in electrolyte transporting epithelia : structure-function correlations

Dennis Brown, I. Sabolić, S. Breton, 2000 .

Loss of brush-border proteins in cadmium-induced nephrotoxicity in rat

Dennis Brown, I. Sabolić, M. Blanuša, 2000 .

Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin.

Dennis Brown, I. Sabolić, S. Breton, 2006, Toxicology.

Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation

Dennis Brown, T. Paunescu, V. Marshansky, 2015, Scientific Reports.

Endosomal pathways for water channel and proton pump recycling in kidney epithelial cells

Dennis Brown, D. Brown, I. Sabolić, 1993, Journal of Cell Science.

Ionic imbalance, in addition to molecular crowding, abates cytoskeletal dynamics and vesicle motility during hypertonic stress

Paolo Meda, P. Meda, Dennis Brown, 2015, Proceedings of the National Academy of Sciences.

Transcellular water transport and stability of expression in aquaporin 1-transfected LLC-PK1 cells in the development of a portable bioartificial renal tubule device.

Dennis Brown, J. Itoh, A. Saito, 2004, Tissue engineering.

Physiological importance of endosomal acidification: potential role in proximal tubulopathies

D. Ausiello, Dennis Brown, V. Marshansky, 2002, Current opinion in nephrology and hypertension.

Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression.

H. Kobori, J. Ingelfinger, Dennis Brown, 2009, American journal of physiology. Renal physiology.

fluorescent protein in transgenic mice Renal principal cell-specific expression of green

L. Zharkikh, Xiaohong Zhu, Dennis Brown, 2016 .

Impaired tubular uptake explains albuminuria in early diabetic nephropathy.

B. Molitoris, W. Comper, Dennis Brown, 2009, Journal of the American Society of Nephrology : JASN.

Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling*

Dennis Brown, N. Pastor-Soler, Christopher R. Brown, 2005, Journal of Biological Chemistry.

Protein phosphatase 2C is responsible for VP-induced dephosphorylation of AQP2 serine 261.

Dennis Brown, R. Bouley, Pui W Cheung, 2017, American journal of physiology. Renal physiology.

Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.

Ruth C Lovering, R. Lovering, Dennis Brown, 2003, Molecular cell.

Defining kidney biology to understand renal disease.

A. McMahon, Dennis Brown, O. Weisz, 2014, Clinical journal of the American Society of Nephrology : CJASN.

The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer

D. Sgroi, S. Naber, Dennis Brown, 2016, Oncotarget.

The a 3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer

D. Sgroi, S. Naber, Dennis Brown, 2016 .

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

R. Xavier, K. Lassen, Dennis Brown, 2019, PLoS genetics.

LLC-PK1 Cell Growth Is Repressed by WT1 Inhibition of G-protein αi−2 Protooncogene Transcription (*)

L. Ercolani, V. Sukhatme, Dennis Brown, 1995, The Journal of Biological Chemistry.

kidney and male reproductive system of transgenic mice Expression of an AQP2 Cre recombinase transgene in

D. Ausiello, Dennis Brown, P. Stricklett, 2016 .

Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells.

M. Mckee, Dennis Brown, C. Belleannée, 2011, American journal of physiology. Cell physiology.

Erratum: Deletion of hensin/DMBT1 blocks conversion of ß- to a-intercalated cells and induces distal renal tubular acidosis (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 50 (21872 -21877) DOI: 10.1073/pnas.1010364107)

M. Mckee, Dennis Brown, F. Cheema, 2012 .

Microheterogeneity of protein and sterol content in kidney podocyte membrane

L. Orci, Dennis Brown, Amreek Singh, 1981, Nature.

Characterization and Cell Distribution of Polycystin, the Product of Autosomal Dominant Polycystic Kidney Disease Gene 1

M. Mclaughlin, M. Arnaout, Dennis Brown, 1996, Molecular medicine.

The V‐ATPase is expressed in the choroid plexus and mediates cAMP‐induced intracellular pH alterations

Dennis Brown, T. Paunescu, J. Praetorius, 2017, Physiological reports.

Renal V‐ATPase: Physiology and Pathophysiology

Dennis Brown, V. Marshansky, 2005 .

Imaging Protein Trafficking

Dennis Brown, Dennis Brown, 2006, Nephron Experimental Nephrology.

Localization of membrane-associated carbonic anhydrase type IV in kidney epithelial cells.

W. Sly, Dennis Brown, D. Brown, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice.

A. Verkman, Dennis Brown, Baoxue Yang, 1999, The Journal of clinical investigation.

Reply to Edemir: Physiological regulation and single-cell RNA sequencing

Jae Wook Lee, Dennis Brown, T. Paunescu, 2018, Proceedings of the National Academy of Sciences.

Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues.

A. Verkman, Dennis Brown, D. Brown, 1995, Journal of cell science.

The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose.

M. Hediger, Dennis Brown, W. S. Lee, 1994, The Journal of clinical investigation.

Intracellular sites of AQP2 S256 phosphorylation identified using inhibitors of the AQP2 recycling itinerary.

Dennis Brown, R. Bouley, A. Nair, 2022, American journal of physiology. Renal physiology.

Selectively amplified expression of an isoform of the vacuolar H(+)-ATPase 56-kilodalton subunit in renal intercalated cells.

Dennis Brown, R. Nelson, X. Guo, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells.

D. Ausiello, Dennis Brown, D. Brown, 1997, The American journal of physiology.

Immunolocalization and tissue-specific splicing of AE2 anion exchanger in mouse kidney.

Dennis Brown, S. Alper, D. Brown, 1998, Journal of the American Society of Nephrology.

Cloning and characterization of the urea transporter UT3: localization in rat kidney and testis.

M. Hediger, Dennis Brown, H. Tsukaguchi, 1997, The Journal of clinical investigation.

Differential localization of two glucose transporter isoforms in rat kidney.

H. Lodish, Dennis Brown, B. Thorens, 1990, The American journal of physiology.