C. Birchmeier

发表

Cell fixation and preservation for droplet-based single-cell transcriptomics

Salah Ayoub, C. Kocks, N. Rajewsky, 2017, BMC Biology.

Targeting MET in cancer: rationale and progress

W. Birchmeier, C. Birchmeier, E. Gherardi, 2012, Nature Reviews Cancer.

Met, metastasis, motility and more

W. Birchmeier, C. Birchmeier, E. Gherardi, 2003, Nature Reviews Molecular Cell Biology.

A Validated Regulatory Network for Th17 Cell Specification

Richard Bonneau, Aviv Madar, Alex Greenfield, 2012, Cell.

Control of Peripheral Nerve Myelination by the ß-Secretase BACE1

P. Saftig, M. Citron, C. Birchmeier, 2006, Science.

Targeting MET in cancer: rationale and progress

Carmen Birchmeier, Walter Birchmeier, W. Birchmeier, 2012, Nature Reviews Cancer.

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

Carmen Birchmeier, Stefan Isenmann, Adriano Aguzzi, 1995, Nature.

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

Holger Gerhardt, Michael Krauss, Carmen Birchmeier, 2018, Cell.

Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis

C. Birchmeier, M. Bonnin, D. Duprez, 2016, eLife.

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

Carmen Birchmeier, Nikolaus Rajewsky, Christian Rosenmund, 2017, Science.

Met provides essential signals for liver regeneration.

Carmen Birchmeier, Christian Trautwein, C. Trautwein, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

M. Selbach, C. Birchmeier, G. Lewin, 2018, Genes & development.

Characterization of an activated human ros gene

M. Wigler, D. Birnbaum, C. Birchmeier, 1986, Molecular and Cellular Biology.

Characterization of an activated human ros

M. Wigler, D. Birnbaum, C. Birchmeier, 2022 .

Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest

U. Suter, A. Furlan, P. Ernfors, 2012, Development.

Insm 1 cooperates with Neurod 1 and Foxa 2 to maintain mature pancreatic b-cell function

Carmen Birchmeier, Nikolaus Rajewsky, Wei Sun, 2015 .

Insm 1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes 1

C. Birchmeier, H. Wildner, Shiqi Jia, 2015 .

Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage

C. Birchmeier, M. Strehle, H. Wildner, 2008, Development.

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3

C. Birchmeier, E. Gomes, E. Vasyutina, 2012, EMBO reports.

Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells

A. Akalin, C. Birchmeier, V. Franke, 2020, Nature Communications.

SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta

K. Rottner, T. Stradal, C. Birchmeier, 2021, bioRxiv.

Epithelial-mesenchymal transitions in cancer progression.

W. Birchmeier, C. Birchmeier, B. Brand-Saberi, 1996, Acta anatomica.

The tyrosine phosphatase Shp2 in development and cancer.

W. Birchmeier, C. Birchmeier, M. Rosário, 2010, Advances in cancer research.

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7

C. Kocks, N. Rajewsky, A. Spuler, 2019, Nature Communications.

Mesenchymal-epithelial transitions.

W. Birchmeier, C. Birchmeier, 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.

Conservation and divergence of RAS protein function during evolution.

M. Wigler, T. Toda, S. Powers, 1985, Cold Spring Harbor symposia on quantitative biology.

Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c‐Met

C. Birchmeier, A. Buchmann, M. Schwarz, 2009, International journal of cancer.

Haploinsufficiency of Insm1 Impairs Postnatal Baseline β-Cell Mass

C. Birchmeier, Cunchuan Wang, Shao-qiang Lin, 2018, Diabetes.

Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1.

C. Birchmeier, H. Wildner, Shiqi Jia, 2015, Developmental biology.

Characterization of the ros1-gene products expressed in human glioblastoma cell lines.

M. Wigler, J. Nikawa, L. Rodgers, 1989, Oncogene research.

β-Secretase BACE1 Is Required for Normal Cochlear Function

H. Schulze, C. Alzheimer, C. Birchmeier, 2019, The Journal of Neuroscience.

Sensory Axon-Derived Neuregulin-1 Is Required for Axoglial Signaling and Normal Sensory Function But Not for Long-Term Axon Maintenance

S. McMahon, C. Birchmeier, D. Bennett, 2009, The Journal of Neuroscience.

Human satellite cells have regenerative capacity and are genetically manipulable.

A. Spuler, Z. Izsvák, Andreas Marg, 2014, The Journal of clinical investigation.

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.

C. Birchmeier, E. Gherardi, 1998, Trends in cell biology.

This information is current as Skin Immunity Key Regulator of Dendritic Cell Migration in The HGF Receptor / Met Tyrosine Kinase Is a

C. Birchmeier, M. Zenke, T. Hieronymus, 2012 .

Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo.

C. Birchmeier, B. Brand-Saberi, B. Christ, 1996, Developmental biology.

SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis

S. Tapscott, C. Birchmeier, V. Mouly, 2020, Development.

240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25–27 January 2019, Hoofddorp, The Netherlands

K. Patel, F. Muntoni, C. Bönnemann, 2019, Neuromuscular Disorders.

Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest

C. Birchmeier, H. Enomoto, Z. Chettouh, 2017, Proceedings of the National Academy of Sciences.

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.

C. Birchmeier, D. Meyer, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The breast proto-oncogene, HRGα regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland

C. Birchmeier, F. Jones, Weiwen Long, 2002, Oncogene.

Multiple essential functions of neuregulin in development

C. Birchmeier, D. Meyer, 1995, Nature.

Tyrosine kinase receptors in the control of epithelial growth and morphogenesis during development

C. Birchmeier, K. M. Weidner, B. Walter, 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

Carmen Birchmeier, Konstantin Radyushkin, Hannelore Ehrenreich, 2008, Neuron.

Axonally Derived Neuregulin-1 Is Required for Remyelination and Regeneration after Nerve Injury in Adulthood

N. Lago, C. Birchmeier, D. Bennett, 2011, The Journal of Neuroscience.

Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase.

M. Wigler, C. Birchmeier, J. Colicelli, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands.

L. Cantley, C. Birchmeier, K. Spokes, 1997, The American journal of physiology.

Expression of the met-receptor and its ligand, HGF-SF during mouse embryogenesis.

C. Birchmeier, K. M. Weidner, E. Sonnenberg, 1993, EXS.

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake

M. Blüher, A. Schürmann, C. Birchmeier, 2020, Proceedings of the National Academy of Sciences.

Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting

L. Kaderali, C. Birchmeier, F. Luft, 2021, Journal of cachexia, sarcopenia and muscle.

Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin

U. Suter, P. Ernfors, D. Usoskin, 2009, Cell.

Molecular Aspects of Epithelial-Mesenchymal Interactions

C. Birchmeier, 1993 .

Sustained MAPK/ERK Activation in Adult Schwann Cells Impairs Nerve Repair

C. Birchmeier, D. Bennett, J. Galino, 2017, The Journal of Neuroscience.

ErbB2 Signaling in Schwann Cells Is Mostly Dispensable for Maintenance of Myelinated Peripheral Nerves and Proliferation of Adult Schwann Cells after Injury

U. Suter, C. Birchmeier, S. Atanasoski, 2006, The Journal of Neuroscience.

3' editing of mRNAs: sequence requirements and involvement of a 60-nucleotide RNA in maturation of histone mRNA precursors.

C. Birchmeier, D. Schümperli, M. Birnstiel, 1984, Proceedings of the National Academy of Sciences of the United States of America.

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling

H. Kettenmann, C. Birchmeier, F. Rathjen, 2022, bioRxiv.

The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse

C. Birchmeier, C. Brakebusch, H. Wende, 2009, Proceedings of the National Academy of Sciences.

gene. of an activated human ros

M. Wigler, D. Birnbaum, C. Birchmeier, 2012 .

Characterization ofanActivated HumanrosGene

C. Birchmeier, G. Waitches, ColdSpriiig HarborLaboratorn, 1986 .

The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei

C. Birchmeier, M. Treier, Justyna Cholewa-Waclaw, 2009, Development.

Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts.

W. Birchmeier, C. Birchmeier, H. Eppenberger, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Studies in Saccharomyces cerevisiae

J. Nikawa, S. Cameron, T. Toda, 2013 .

Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

K. Rajewsky, M. Selbach, W. Birchmeier, 2014, Genes & development.

Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae.

M. Wigler, L. Rodgers, C. Birchmeier, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice

C. Birchmeier, Stephan Dietrich, N. Zampieri, 2022, Nature Communications.

The molecular foundation of proprioceptor muscle-type identity

C. Birchmeier, Stephan Dietrich, N. Zampieri, 2022, bioRxiv.

Fructose 1,6-bisphosphate sensing by pyruvate kinase isozymes M2 (PKM2) controls MyoD stability and myogenic differentiation

C. Birchmeier, Minchul Kim, Yao Zhang, 2020, bioRxiv.

Generation of authentic 3′ termini of an H2A mRNA in vivo is dependent on a short inverted DNA repeat and on spacer sequences

R. Grosschedl, C. Birchmeier, M. Birnstiel, 1982, Cell.

The homeodomain factor Lbx1 controls the differentiation of sensory relay neurons in the hindbrain

G. Aramuni, C. Birchmeier, M. Dutschmann, 2006, International Journal of Developmental Neuroscience.

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice.

C. Trautwein, N. Gassler, C. Birchmeier, 2009, Gastroenterology.

Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

C. Birchmeier, D. Meyer, K. M. Weidner, 1993, The Journal of cell biology.

A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis

E. Fuchs, N. Copeland, N. Jenkins, 2012, The EMBO journal.

Axonal Neuregulin-1 Regulates Myelin Sheath Thickness

Carmen Birchmeier, Tobias M. Fischer, Klaus-Armin Nave, 2004, Science.

A medullary centre for lapping in mice

Evan R. Harrell, J. Poulet, A. Genovesio, 2021, Nature Communications.

Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling

Carmen Birchmeier, Jan Baumgart, Nils Brose, 2009, Cell.

The transcription factor Sox10 is a key regulator of peripheral glial development.

K. Nave, M. Wegner, D. Riethmacher, 2001, Genes & development.

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis

M. Gaestel, H. Volk, C. Birchmeier, 1999, Nature Cell Biology.

Sustained Long Term Potentiation and Anxiety in Mice Lacking theMas Protooncogene*

D. Ganten, T. Walther, D. Balschun, 1998, The Journal of Biological Chemistry.

Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest

Zizhen Yao, Yi Cao, C. Birchmeier, 2014, Development.

Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains

M. Wigler, C. Birchmeier, D. Young, 1986, Cell.

A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development.

D. Riethmacher, C. Birchmeier, V. Brinkmann, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The HGF Receptor/Met Tyrosine Kinase Is a Key Regulator of Dendritic Cell Migration in Skin Immunity

C. Birchmeier, M. Zenke, T. Hieronymus, 2012, The Journal of Immunology.

The Homeodomain Factor Lbx1 Distinguishes Two Major Programs of Neuronal Differentiation in the Dorsal Spinal Cord

T. Jessell, A. Pierani, C. Birchmeier, 2002, Neuron.

RAS proteins can induce meiosis in xenopus oocytes

M. Wigler, C. Birchmeier, D. Broek, 1985, Cell.

Self-Organizing 3D Human Trunk Neuromuscular Organoids.

S. Sauer, P. Ruffault, C. Birchmeier, 2020, Cell stem cell.

The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis.

D. Riethmacher, C. Birchmeier, E. Sonnenberg-Riethmacher, 1996, Genes & development.

Neuregulin‐1, a key axonal signal that drives Schwann cell growth and differentiation

K. Nave, C. Birchmeier, 2008, Glia.

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors

M. Selbach, C. Birchmeier, F. Paul, 2013, Development.

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

D. Riethmacher, C. Birchmeier, G. Lewin, 1997, Nature.

Notch Function in Myogenesis

C. Birchmeier, D. Lenhard, E. Vasyutina, 2007, Cell cycle.

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells

J. Epstein, C. Birchmeier, B. Erdmann, 2007, Proceedings of the National Academy of Sciences.

Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.

C. Birchmeier, Maciej T. Czajkowski, D. Lenhard, 2014, Developmental biology.

Colonization of the satellite cell niche by skeletal muscle progenitor cells depends on Notch signals.

H. Rahn, C. Birchmeier, Maciej T. Czajkowski, 2012, Developmental cell.

The development of migrating muscle precursor cells

C. Birchmeier, E. Vasyutina, 2006, Anatomy and Embryology.

The role of SF/HGF and c-Met in the development of skeletal muscle.

C. Birchmeier, F. Abou-Rebyeh, B. Brand-Saberi, 1999, Development.

THE ROLE OF SF/HGF AND C-MET IN THE MIGRATION OF MYOGENIC PRECURSOR CELLS DURING DEVELOPMENT OF THE TONGUE, THE LIMBS AND THE DIAPHRAGM(Developmental Biology)(Proceedings of the Sixty-Ninth Annual Meeting of the Zoological Society of Japan)

C. Birchmeier, F. Bladt, Y. Yamaai, 1998 .

Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons

M. Hanson, M. Tessier-Lavigne, A. Ebens, 1996, Neuron.

Cell fixation and preservation for droplet-based single-cell transcriptomics

Salah Ayoub, C. Kocks, N. Rajewsky, 2017, bioRxiv.

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

W. Birchmeier, C. Birchmeier, D. Meyer, 1995, The Journal of cell biology.

A Role for E2F6 in the Restriction of Male-Germ-Cell-Specific Gene Expression

C. Birchmeier, M. Strehle, R. Kuban, 2005, Current Biology.

Oscillations of Delta-like1 regulate the balance between differentiation and maintenance of muscle stem cells

R. Kageyama, J. Wolf, C. Birchmeier, 2021, Nature Communications.

Oscillations of MyoD and Hes1 proteins regulate the maintenance of activated muscle stem cells

S. Preibisch, R. Kageyama, J. Wolf, 2019, Genes & development.

Parasympathetic neurons originate from nerve-associated peripheral glial progenitors

K. Fried, Fatima Memic, A. Furlan, 2014, Science.

Loss of Ptpn11 (Shp2) drives satellite cells into quiescence

C. Birchmeier, M. Nazaré, Charles Keller, 2017, eLife.

Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain

F. Guillemot, C. Birchmeier, J. Briscoe, 2009, Development.

The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells.

C. Birchmeier, M. Strehle, H. Wende, 2006, Genes & development.

Short- and Long-Range Attraction of Cortical GABAergic Interneurons by Neuregulin-1

Tobias M. Fischer, O. Marín, J. Rubenstein, 2004, Neuron.

A Role for Neuregulin1 Signaling in Muscle Spindle Differentiation

S. Arber, T. Jessell, S. Hippenmeyer, 2002, Neuron.

Requirement for beta-catenin in anterior-posterior axis formation in mice.

Carmen Birchmeier, Walter Birchmeier, Volker Brinkmann, 2000 .

The Transcription Factor c-Maf Controls Touch Receptor Development and Function

C. Birchmeier, G. Lewin, S. G. Lechner, 2012, Science.

Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.

W. Birchmeier, M. Taketo, C. Birchmeier, 2007, Developmental biology.

CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells.

S. Schulz, C. Birchmeier, E. Raz, 2005, Genes & development.

Patterning of Muscle Acetylcholine Receptor Gene Expression in the Absence of Motor Innervation

S. Arber, T. Jessell, Y. Tanabe, 2001, Neuron.

Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo

W. Birchmeier, C. Birchmeier, D. Zechner, 2000, The Journal of cell biology.

The role of Lbx1 in migration of muscle precursor cells.

K. Jagla, C. Birchmeier, H. Brohmann, 2000, Development.

Homeobox genes encode DNA-binding transcription factors that can regulate axial patterning, segment or cell identity, and proliferation. The classical homeobox genes are organised in clusters and determine the basic body plan of animals

K. Jagla, C. Birchmeier, H. Brohmann, 1999 .

The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system.

D. Riethmacher, C. Birchmeier, S. Kirchhoff, 1998, Genes & development.

Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis.

C. Birchmeier, W. Muller, H. Lahlou, 2012, Cancer research.

Genes that control the development of migrating muscle precursor cells.

C. Birchmeier, H. Brohmann, Henning Brohmann, 2000, Current opinion in cell biology.

The branchial arches and HGF are growth-promoting and chemoattractant for cranial motor axons.

J. Livet, R. Klein, C. Birchmeier, 2000, Development.

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system.

Carmen Birchmeier, Dietmar Zechner, Walter Birchmeier, 2003, Developmental biology.

Characterization of two new human oncogenes.

M. Wigler, C. Birchmeier, D. Young, 1986, Cold Spring Harbor symposia on quantitative biology.

The bHLH factor Olig3 coordinates the specification of dorsal neurons in the spinal cord.

C. Birchmeier, H. Wildner, Katrin Anlag, 2005, Genes & development.

Ontogeny of Excitatory Spinal Neurons Processing Distinct Somatic Sensory Modalities

C. Birchmeier, Cláudia Lopes, Yi Xu, 2013, The Journal of Neuroscience.

Nociceptive Tuning by Stem Cell Factor/c-Kit Signaling

Carmen Birchmeier, Gary R. Lewin, Max Gassmann, 2007, Neuron.

Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation

T. Wienker, H. Ropers, C. Birchmeier, 2017, PLoS genetics.

Nrg1/ErbB signaling networks in Schwann cell development and myelination.

C. Birchmeier, J. Newbern, 2010, Seminars in cell & developmental biology.

Molecular aspects of mesenchymal-epithelial interactions.

W. Birchmeier, C. Birchmeier, 1993, Annual review of cell biology.

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

M. Wigler, T. Toda, S. Powers, 1987, Cell.

RNA localization is a key determinant of neurite-enriched proteome

N. Rajewsky, E. Mazzoni, M. Selbach, 2017, Nature Communications.

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development

N. Copeland, N. Jenkins, F. Luyten, 2012, Development.

Activating Met mutations produce unique tumor profiles in mice with selective duplication of the mutant allele.

M. Fiscella, G. V. Vande Woude, R. Bronson, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo

W. Birchmeier, G. Winter, C. Birchmeier, 1998, Current Biology.

Epithelial differentiation and the control of metastasis in carcinomas.

W. Birchmeier, C. Birchmeier, J. Behrens, 1996, Current topics in microbiology and immunology.

Genetic identification of a hindbrain nucleus essential for innate vocalization

Elodie Ey, Carmen Birchmeier, Niccolò Zampieri, 2017, Proceedings of the National Academy of Sciences.

GENETICS OF CELL PROLIFERATION

S. Cameron, T. Toda, D. Birnbaum, 2013 .

Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling

J. Chun, D. Schmitz, J. Breustedt, 2011, Cell.

Characterization of an activated human ros gene

M. Wigler, D. Birnbaum, C. Birchmeier, 1986, Molecular and cellular biology.

Isoform-specific expression and function of neuregulin.

C. Birchmeier, D. Meyer, L. Theill, 1997, Development.

Multiple essential functions of neuregulin in development

Carmen Birchmeier, C. Birchmeier, D. Meyer, 1995, Nature.

Teashirt 1 (Tshz1) is essential for the development, survival and function of hypoglossal and phrenic motor neurons in mouse

G. Fortin, P. Ruffault, C. Birchmeier, 2019, Development.

The terminal RNA stem-loop structure and 80 bp of spacer DNA are required for the formation of 3′ termini of sea urchin H2A mRNA

C. Birchmeier, W. Folk, M. Birnstiel, 1983, Cell.

Negative Regulation of Ros Receptor Tyrosine Kinase Signaling

W. Birchmeier, C. Birchmeier, H. Kosmehl, 2001, The Journal of cell biology.

The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

M. Selbach, W. Birchmeier, H. Schulz, 2009, Proceedings of the National Academy of Sciences.

Transient and locally restricted expression of the ros1 protooncogene during mouse development.

C. Birchmeier, A. Gödecke, F. Bladt, 1991, The EMBO journal.

Epithelial-mesenchymal transitions in development and tumor progression.

W. Birchmeier, C. Birchmeier, 1995, EXS.

ErbB receptors and the development of the nervous system.

Carmen Birchmeier, C. Birchmeier, 2009, Experimental cell research.

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

K. Nave, P. Saftig, C. Birchmeier, 2013, The EMBO journal.

Neuregulin, a factor with many functions in the life of a Schwann cell

C. Birchmeier, A. Garratt, S. Britsch, 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

Neuregulin-3 in the Mouse Medial Prefrontal Cortex Regulates Impulsive Action

R. Loo, A. Smit, S. Spijker, 2014, Biological Psychiatry.

A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.

J. Epstein, C. Birchmeier, T. Masui, 2008, Genes & development.

A Dual Role of erbB2 in Myelination and in Expansion of the Schwann Cell Precursor Pool

C. Birchmeier, A. Garratt, P. Topilko, 2000, The Journal of cell biology.

Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development.

P. Caroni, D. Riethmacher, R. Harvey, 1999, Genes & development.

The transcription factor c-Maf in sensory neuron development

C. Birchmeier, S. G. Lechner, H. Wende, 2012, Transcription.

Quantitative Proteomics Reveals Dynamic Interaction of c-Jun N-terminal Kinase (JNK) with RNA Transport Granule Proteins Splicing Factor Proline- and Glutamine-rich (Sfpq) and Non-POU Domain-containing Octamer-binding Protein (Nono) during Neuronal Differentiation*

M. Selbach, C. Birchmeier, L. Hernandez-Miranda, 2014, Molecular & Cellular Proteomics.

Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons

J. Poulet, C. Birchmeier, Maria E Sheean, 2018, The EMBO journal.

ESICM LIVES 2016: part two

A. M. Cavalheiro, H. S. King, M. M. Moraes, 2016, Intensive Care Medicine Experimental.

Differential expression of neurotrophin receptors during renal development.

C. Birchmeier, S. Söderström, T. Ebendal, 1993, Development.

ErbB2 pathways in heart and neural diseases.

Carmen Birchmeier, C. Birchmeier, A. Garratt, 2003, Trends in cardiovascular medicine.

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

W. Birchmeier, F. Vogel, C. Birchmeier, 1996, The Journal of cell biology.

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy

Carmen Birchmeier, Norbert Hübner, N. Hübner, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Context-specific regulation of cell survival by a miRNA-controlled BIM rheostat

C. Kocks, N. Rajewsky, K. Rajewsky, 2019, Genes & development.

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.

R. Fodde, R. Smits, C. Birchmeier, 2000, Gastroenterology.

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.

M. Gaestel, C. Birchmeier, A. Kotlyarov, 1999, Nature cell biology.

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury

S. McMahon, C. Birchmeier, D. Bennett, 2016, Brain : a journal of neurology.

Kotlyarov, A. et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1, 94-97

M. Gaestel, C. Birchmeier, A. Kotlyarov, 1999 .

Factors controlling growth, motility, and morphogenesis of normal and malignant epithelial cells.

D. Riethmacher, C. Birchmeier, D. Meyer, 1995, International review of cytology.

dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development

F. Guillemot, C. Cepko, C. Birchmeier, 2006, Development.

Expression and rearrangement of the ROS1 gene in human glioblastoma cells.

M. Wigler, C. Birchmeier, S. Sharma, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination

Carmen Birchmeier, Stefan G. Lechner, C. Birchmeier, 2017, Neuron.

Insulinoma-Associated 1 Has a Panneurogenic Role and Promotes the Generation and Expansion of Basal Progenitors in the Developing Mouse Neocortex

S. Pääbo, P. Khaitovich, W. Huttner, 2008, Neuron.

Prox2+ and Runx3+ neurons regulate esophageal motility

Aristotelis Misios, N. Rajewsky, P. Ruffault, 2022, bioRxiv.

Isoform-specific knockout of the Neuregulin-1 gene

W. Doerfler, C. Birchmeier, Li Li, 2003 .

Neuregulin 1 Sustains the Gene Regulatory Network in Both Trabecular and Nontrabecular Myocardium

D. Fatkin, R. Harvey, C. Birchmeier, 2010, Circulation research.

Neuregulin-1 mutant mice indicate motor and sensory deficits, indeed few references for schizophrenia endophenotype model

C. Birchmeier, H. Schwegler, T. Roskoden, 2017, Behavioural Brain Research.

Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development

W. Birchmeier, K. Nave, C. Birchmeier, 2013, Proceedings of the National Academy of Sciences.

Human Midbrain Organoids for In Vitro Modeling of Parkinson ’ s Disease

C. Schmidt-Hieber, R. Rodenburg, C. Birchmeier, 2019 .

Characterization and expression analysis of the murine rck gene: a protein kinase with a potential function in sensory cells.

C. Birchmeier, F. Bladt, 1993, Differentiation; research in biological diversity.

c-Met is essential for wound healing in the skin

S. Werner, W. Birchmeier, J. Wehland, 2007, The Journal of cell biology.

c-Met is essential for wound healing

S. Werner, W. Birchmeier, J. Wehland, 2008 .

Neuregulin/ErbB Signaling in Developmental Myelin Formation and Nerve Repair.

C. Birchmeier, D. Bennett, 2016, Current topics in developmental biology.

Technologies for profiling the impact of genomic variants on transcription factor binding

U. Heinemann, C. Birchmeier, K. Schmidt-Ott, 2021, Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V.

pancreatic The Zinc-finger factor Insm 1 ( IA-1 ) is essential for the development of Material Supplemental

C. Birchmeier, M. Strehle, H. Wende, 2006 .

RNA localization is a key determinant of neurite-enriched proteome

N. Rajewsky, E. Mazzoni, M. Selbach, 2017, Nature Communications.

The dorsal spinal cord and hindbrain: From developmental mechanisms to functional circuits.

C. Birchmeier, L. Hernandez-Miranda, T. Müller, 2017, Developmental biology.

BMP signaling regulates satellite cell-dependent postnatal muscle growth

C. Colnot, M. Schuelke, C. Birchmeier, 2017, Development.

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.

K. Nave, C. Birchmeier, M. Strehle, 2008, Developmental biology.

Self-Organizing 3D Human Trunk Neuromuscular Organoids.

S. Sauer, P. Ruffault, C. Birchmeier, 2020, Cell stem cell.

Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations

C. Birchmeier, U. Schweizer, Wenchao Zhao, 2019, The Journal of Biological Chemistry.

Defective Respiratory Rhythmogenesis and Loss of Central Chemosensitivity in Phox2b Mutants Targeting Retrotrapezoid Nucleus Neurons

M. Thoby-Brisson, G. Fortin, C. Birchmeier, 2009, The Journal of Neuroscience.

Genome-Wide Expression Analysis of Ptf1a- and Ascl1-Deficient Mice Reveals New Markers for Distinct Dorsal Horn Interneuron Populations Contributing to Nociceptive Reflex Plasticity

C. Birchmeier, P. Heppenstall, H. Wildner, 2013, The Journal of Neuroscience.

Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways

C. Birchmeier, E. Coppola, J. Brunet, 2011, Proceedings of the National Academy of Sciences.

Lbx1 Acts as a Selector Gene in the Fate Determination of Somatosensory and Viscerosensory Relay Neurons in the Hindbrain

C. Birchmeier, M. Martı́nez-de-la-Torre, H. Wende, 2007, The Journal of Neuroscience.

Characterization of ROS1 cDNA from a human glioblastoma cell line.

M. Wigler, C. Birchmeier, M. Riggs, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Human ros1 and mas1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements.

M. Wigler, D. Birnbaum, F. Ruddle, 1987, Oncogene research.

The functions of HGF/SF and its receptor, the c-Met tyrosine kinase, in mammalian development.

C. Birchmeier, T. Yamaai, F. Bladt, 1997, Ciba Foundation symposium.

Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function

Carmen Birchmeier, Nikolaus Rajewsky, Wei Sun, 2015, The EMBO journal.

Mechanisms and Neuronal Control of Vocalization in Vertebrates

C. Birchmeier, L. Hernandez-Miranda, 2018 .

An executive center for the intake of liquids

Evan R. Harrell, J. Poulet, A. Genovesio, 2021, bioRxiv.

Mutations in MYO1H cause a recessive form of central hypoventilation with autonomic dysfunction

S. Mundlos, M. Spielmann, P. Krawitz, 2017, Journal of Medical Genetics.

Requirement for β-Catenin in Anterior-Posterior Axis Formation in Mice

Carmen Birchmeier, Walter Birchmeier, Volker Brinkmann, 2000, The Journal of cell biology.

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility

N. Vladimirov, Aristotelis Misios, N. Rajewsky, 2023, Neuron.

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

C. Birchmeier, Karolina Werynska, H. Wildner, 2023, Cell reports.

A role of the cryptic gene in the correct establishment of the left–right axis

C. Birchmeier, A. Garratt, C. Özcelik, 1999, Current Biology.

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination

Carmen Birchmeier, Christine Orengo, Stephen B. McMahon, 2013, Brain : a journal of neurology.

myelination replaces Nrg 1 / ErbB 3 signals during Schwann cell development and Activation of MAPK overrides the termination of myelin growth and Material

K. Rajewsky, M. Selbach, W. Birchmeier, 2014 .

Biochemical and functional characterization of the murine ros protooncogene.

D. Riethmacher, C. Birchmeier, M. Sachs, 1994, Oncogene.

Prox2 and Runx3 vagal sensory neurons regulate esophageal motility

N. Vladimirov, Aristotelis Misios, N. Rajewsky, 2023, Neuron.

An oscillatory network controlling self-renewal of skeletal muscle stem cells.

J. Wolf, C. Birchmeier, Ines Lahmann, 2021, Experimental cell research.

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

A. Müller, A. Schürmann, C. Birchmeier, 2019, bioRxiv.

Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice

S. Mundlos, G. Fortin, P. Ruffault, 2018, Proceedings of the National Academy of Sciences.

Touch Receptor-Derived S ensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination Highlights

C. Birchmeier, S. G. Lechner, P. Heppenstall, 2016 .

Regulation of developmental tempo in different vertebrate species.

C. Birchmeier, 2023, Cell stem cell.

Targeting MET in cancer: rationale and progress

W. Birchmeier, C. Birchmeier, E. Gherardi, 2012, Nature Reviews Cancer.

ESICM LIVES 2016: part two

A. M. Cavalheiro, H. S. King, H. Z. Chai, 2016, Intensive care medicine experimental.

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

W. Birchmeier, C. Birchmeier, D. Meyer, 1995, The Journal of cell biology.

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling in mice

H. Kettenmann, C. Birchmeier, F. Rathjen, 2023, bioRxiv.

Requirement for β-Catenin in Anterior-Posterior Axis Formation in Mice

W. Birchmeier, C. Birchmeier, B. Erdmann, 2000, The Journal of cell biology.

The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei

C. Birchmeier, M. Treier, Justyna Cholewa-Waclaw, 2009, Development.

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors

M. Selbach, C. Birchmeier, F. Paul, 2013, Development.

Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development

N. Copeland, N. Jenkins, F. Luyten, 2012, Development.

c-Met is essential for wound healing in the skin

S. Werner, W. Birchmeier, J. Wehland, 2007, The Journal of cell biology.

Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3

C. Birchmeier, E. Gomes, E. Vasyutina, 2012, EMBO reports.

The HGF Receptor/Met Tyrosine Kinase Is a Key Regulator of Dendritic Cell Migration in Skin Immunity

C. Birchmeier, M. Zenke, T. Hieronymus, 2012, The Journal of Immunology.

Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c‐Met

C. Birchmeier, A. Buchmann, M. Schwarz, 2009, International journal of cancer.