C. Samuel

C. Samuel, C. George, A. Toth, 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).

C. Samuel, C. George, Lijo John, 2014, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Adenosine deaminases acting on RNA, RNA editing, and interferon action.

Yong Liu, Charles E Samuel, Yong Liu, 2011, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase

C. Samuel, D. Thomis, C. E. Samuel, 1995, Journal of virology.

Host genetic variability and West Nile virus susceptibility

C. Samuel, C. E. Samuel, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Virus-Host Interaction Minireview Series: Human Immunodeficiency Virus, Hepatitis C Virus, and Influenza Virus*

C. Samuel, C. E. Samuel, 2006, Journal of Biological Chemistry.

Regulation of the interferon-inducible PKR kinase gene: the KCS element is a constitutive promoter element that functions in concert with the interferon-stimulated response element.

C. Samuel, S. Ward, C. E. Samuel, 2002, Virology.

Mouse interferon-inducible RNA-dependent protein kinase Pkr gene: cloning and sequence of the 5'-flanking region and functional identification of the minimal inducible promoter.

C. Samuel, H. Tanaka, C. E. Samuel, 2000, Gene.

Reoviruses and the interferon system.

C. Samuel, C. E. Samuel, 1998, Current topics in microbiology and immunology.

Serotonin-2C Receptor Pre-mRNA Editing in Rat Brain andin Vitro by Splice Site Variants of the Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1*

R. Emeson, C. Samuel, Yong Liu, 1999, The Journal of Biological Chemistry.

Double-stranded RNA-specific adenosine deaminase: nucleic acid binding properties.

A. Rich, C. Samuel, Y. Liu, 1998, Methods.

The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.

C. Samuel, C. E. Samuel, Charles E. Samuel, 1993, The Journal of biological chemistry.

Mechanism of interferon action: alpha and gamma interferons differentially affect mRNA levels of the catalytic subunit of protein kinase A and protein Mx in human cells

C. Samuel, D. C. Thomas, D. Thomis, 1992, Journal of virology.

PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.

C. Samuel, T. Fujita, Y. Okabe, 2001, Biochemical and biophysical research communications.

Characterization of the 5'-flanking region of the human RNA-specific adenosine deaminase ADAR1 gene and identification of an interferon-inducible ADAR1 promoter.

C. Samuel, C. George, C. E. Samuel, 1999, Gene.

Interleukin-1 beta secretion is activated comparably by FliC and FljB flagellins but differentially by wild-type and DNA adenine methylase-deficient salmonella.

C. Samuel, R. Simon, C. E. Samuel, 2008, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Comparison of Tissue-Selective Proinflammatory Gene Induction in Mice Infected with Wild-Type, DNA Adenine Methylase-Deficient, and Flagellin-Deficient Salmonella enterica

C. Samuel, D. M. Heithoff, M. Mahan, 2007, Infection and Immunity.

Activation of NF-kappaB-dependent gene expression by Salmonella flagellins FliC and FljB.

C. Samuel, R. Simon, C. E. Samuel, 2007, Biochemical and biophysical research communications.

Innate interferon response in macrophage and epithelial cells infected with wild-type compared to DNA adenine methylase and flagellin mutant Salmonella enterica serovar Typhimurium.

C. Samuel, R. Simon, C. E. Samuel, 2007, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Tissue Selectivity of Interferon-Stimulated Gene Expression in Mice Infected with Dam+ versus Dam−Salmonella enterica Serovar Typhimurium Strains

C. Samuel, R. Shtrichman, D. M. Heithoff, 2002, Infection and Immunity.

Lipid–DNA Interactions: Structure–Function Studies of Nanomaterials for Gene Delivery

K. Ewert, C. Samuel, C. Safinya, 2007 .

Protein Kinase PKR Amplification of Interferon β Induction Occurs through Initiation Factor eIF-2α-mediated Translational Control*

C. Samuel, Nora Taghavi, Christopher S McAllister, 2012, Journal of Biological Chemistry.

Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response.

C. Samuel, C. George, Christian K. Pfaller, 2011, Current opinion in immunology.

Assignment1 of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization

C. Samuel, H. Weier, C. George, 2000, Cytogenetic and Genome Research.

ADARs: viruses and innate immunity.

C. Samuel, C. E. Samuel, 2012, Current topics in microbiology and immunology.

Host Response to Polyomavirus Infection Is Modulated by RNA Adenosine Deaminase ADAR1 but Not by ADAR2

C. Samuel, C. George, C. E. Samuel, 2011, Journal of Virology.

The PKR kinase promoter binds both Sp1 and Sp3, but only Sp3 functions as part of the interferon-inducible complex with ISGF-3 proteins.

C. Samuel, S. Ward, C. E. Samuel, 2003, Virology.

Isolation and characterization of a molecular cDNA clone of a human mRNA from interferon-treated cells encoding nucleolar protein B23, numatrin.

C. Samuel, D. Thomis, X. Zhang, 1989, Biochemical and biophysical research communications.

Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells

Jing Wang, J. Roth, I. Wistuba, 2019, Oncogene.

Induction of interferons and interferon-induced genes

K. Ozato, C. Samuel, C. E. Samuel, 1996 .

Mechanism of Interferon Action: Biochemical and Genetic Evidence for the Intermolecular Association of the RNA-Dependent Protein Kinase PKR from Human Cells

C. Samuel, G. Henry, S. Mccormack, 1996 .

Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase.

C. Samuel, S. Mccormack, D. Thomis, 1992, Virology.

RNA Editing Minireview Series*

Charles E Samuel, C. Samuel, C. E. Samuel, 2003, The Journal of Biological Chemistry.

Biosynthesis of reovirus-specified polypeptides. Effect of methylation on the efficiency of reovirus genome expression in vitro.

C. Samuel, K. Levin, Charles E. Samuel, 1977, Virology.

Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase.

C. Samuel, C. George, S. Mccormack, 1996, Virology.

Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA.

Nathan F. Bouxsein, K. Ewert, N. Bouxsein, 2007, Biochemistry.

Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection.

K. Rohr, L. Kaderali, P. Bankhead, 2012, Cell host & microbe.

Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses*

C. Samuel, G. Ramaswami, C. George, 2016, The Journal of Biological Chemistry.

Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1

C. Samuel, Kristina M. Okonski, C. E. Samuel, 2012, Journal of Virology.

NSs Virulence Factor of Rift Valley Fever Virus Engages the F-Box Proteins FBXW11 and β-TRCP1 To Degrade the Antiviral Protein Kinase PKR

F. Weber, V. Hornung, C. Samuel, 2016, Journal of Virology.

Two-dimensional packing of short DNA with nonpairing overhangs in cationic liposome-DNA complexes: from Onsager nematics to columnar nematics with finite-length columns.

Nathan F. Bouxsein, K. Ewert, Youli Li, 2011, Journal of the American Chemical Society.

RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR*

Roberto Cattaneo, C. Samuel, R. Cattaneo, 2009, The Journal of Biological Chemistry.

Methionine transfer ribonucleic acid from folate-sufficient and folate-deficient Streptococcus faecalis R.

C. Samuel, J. Rabinowitz, C. L. Murray, 1972, The Journal of biological chemistry.

Mechanism of interferon action. Studies on the mechanism of interferon-mediated inhibition of reovirus messenger RNA translation in cell-free protein synthesis systems from mouse ascites tumor cells.

C. Samuel, C. E. Samuel, 1976, Virology.

Upon Infection, Cellular WD Repeat-Containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication

C. Samuel, D. Ma, C. George, 2017, Journal of Virology.

Procedures for isolation and assay of translation-inhibitory ribosome-associated proteins.

C. Samuel, C. E. Samuel, 1981, Methods in enzymology.

A comparison of transfer RNA from untreated and interferon-treated murine cells.

C. Samuel, E. Penhoet, C. Colby, 1976, Virology.

Adenosine Deaminases Acting on RNA (ADARs) and Viral Infections.

C. Samuel, C. George, Christian K. Pfaller, 2021, Annual review of virology.

The PKR protein kinase--an interferon-inducible regulator of cell growth and differentiation.

K. Kuhen, C. Samuel, H. Tanaka, 1997, International journal of hematology.

PKR: proposed nomenclature for the RNA-dependent protein kinase induced by interferon.

M. Katze, P. Lengyel, B. Williams, 1993, Journal of interferon research.

Mechanism of interferon action: double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons.

C. Samuel, D. Thomis, J. Patterson, 1995, Virology.

The promoter-proximal KCS element of the PKR kinase gene enhances transcription irrespective of orientation and position relative to the ISRE element and is functionally distinct from the KCS-like element of the ADAR deaminase Promoter.

C. Samuel, Sonali Das, S. Ward, 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Adenovirus VAI RNA antagonizes the RNA-editing activity of the ADAR adenosine deaminase.

C. Samuel, Y. Liu, M Lei, 1998, Virology.

Interaction of the human protein kinase PKR with the mouse PKR homolog occurs via the N-terminal region of PKR and does not inactivate autophosphorylation activity of mouse PKR.

C. Samuel, C. George, R. Rende-Fournier, 1997, Virology.

Biosynthesis of reovirus-specified polypeptides. 2-aminopurine increases the efficiency of translation of reovirus s1 mRNA but not s4 mRNA in transfected cells.

C. Samuel, M. S. Brody, C. E. Samuel, 1990, Virology.

Mechanism of interferon action. Production and characterization of monoclonal and polyclonal antibodies to the interferon-induced phosphoprotein P1.

M. Berry, C. Samuel, C. E. Samuel, 1985, Biochemical and biophysical research communications.

Mechanism of interferon action. The interferon-induced phosphoprotein P1 possesses a double-stranded RNA-dependent ATP-binding site.

C. Samuel, J. Bischoff, C. E. Samuel, 1985, The Journal of biological chemistry.

HIV-1 Tat directly interacts with the interferon-induced, double-stranded RNA-dependent kinase, PKR.

T. Mak, W. Toone, B. Williams, 1995, Virology.

Editing of Glutamate Receptor Subunit B Pre-mRNA by Splice-site Variants of Interferon-inducible Double-stranded RNA-specific Adenosine Deaminase ADAR1*

Yong Liu, C. Samuel, C. E. Samuel, 1999, The Journal of Biological Chemistry.

Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR.

C. Samuel, Y. Liu, M. Lei, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human gamma-interferon. II. Effect on viral macromolecular synthesis.

C. Samuel, N. Ulker, C. E. Samuel, 1985, The Journal of biological chemistry.

Mechanism of interferon action. I. Characterization of a 54-kDa protein induced by gamma interferon with properties similar to a cytoskeletal component.

C. Samuel, N. Ulker, X. Zhang, 1987, The Journal of biological chemistry.

Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor.

C. Samuel, M. Diaz, O. Colamonici, 1994, The Journal of biological chemistry.

Mechanism of interferon action: inhibition of vesicular stomatitis virus replication in human amnion U cells by cloned human leukocyte interferon. I. Effect on early and late stages of the viral multiplication cycle.

C. Samuel, P. Masters, C. E. Samuel, 1983, Journal of Biological Chemistry.

Mechanism of interferon action. Translational control and the RNA-dependent protein kinase (PKR): antagonists of PKR enhance the translational activity of mRNAs that include a 161 nucleotide region from reovirus S1 mRNA.

C. Samuel, G. Henry, S. Mccormack, 1994, Journal of biological regulators and homeostatic agents.