K. Morino

发表

Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

K. Petersen, G. Shulman, K. Morino, 2006, Diabetes.

Insulin-Induced c-Jun N-Terminal Kinase Activation Is Negatively Regulated by Protein Kinase C δ.

K. Morino, H. Maegawa, A. Kashiwagi, 2001, Endocrinology.

Alcohol Drinking and Brain Morphometry in Apparently Healthy Community-Dwelling Japanese Men.

K. Nozaki, T. Ohkubo, I. Tooyama, 2020, Alcohol.

Membrane Localization of 3-Phosphoinositide-dependent Protein Kinase-1 Stimulates Activities of Akt and Atypical Protein Kinase C but Does Not Stimulate Glucose Transport and Glycogen Synthesis in 3T3-L1 Adipocytes*

K. Morino, H. Maegawa, A. Kashiwagi, 2002, The Journal of Biological Chemistry.

Impact of obesity on underreporting of energy intake in type 2 diabetic patients: Clinical Evaluation of Energy Requirements in Patients with Diabetes Mellitus (CLEVER-DM) study.

K. Morino, Shigeho Tanaka, H. Maegawa, 2020, Clinical nutrition ESPEN.

CCDC3 is specifically upregulated in omental adipose tissue in subjects with abdominal obesity

K. Morino, H. Maegawa, A. Kashiwagi, 2014, Obesity.

Autophagy regulates inflammation in adipocytes.

K. Morino, T. Uzu, H. Maegawa, 2012, Biochemical and biophysical research communications.

Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters.

G. Shulman, K. Morino, D. Savage, 2006, American journal of physiology. Endocrinology and metabolism.

Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats.

K. Petersen, P. Perret, G. Cline, 2007, American journal of physiology. Endocrinology and metabolism.

Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis

K. Morino, H. Maegawa, S. Kume, 2017, Diabetes.

Role of Gut Microbiota, Gut-Brain and Gut Liver Axes in Physiological Regulation of Inﬂammation, Energy Balance, and Metabolism Microbiome potentiates endurance exercise through intestinal acetate production

K. Morino, H. Maegawa, Y. Fujita, 2022 .

Low concentration of 4-hydroxy hexenal increases heme oxygenase-1 expression through activation of Nrf2 and antioxidative activity in vascular endothelial cells.

K. Morino, H. Maegawa, A. Kashiwagi, 2010, Biochemical and biophysical research communications.

4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation

K. Morino, T. Uzu, H. Maegawa, 2013, PloS one.

Association between serum soluble TNFα receptors and renal dysfunction in type 2 diabetic patients without proteinuria.

K. Morino, T. Uzu, H. Maegawa, 2011, Diabetes research and clinical practice.

N-3 Polyunsaturated Fatty Acids Decrease the Protein Expression of Soluble Epoxide Hydrolase via Oxidative Stress-Induced P38 Kinase in Rat Endothelial Cells

K. Morino, T. Imamura, H. Maegawa, 2017, Nutrients.

A fish-based diet intervention improves endothelial function in postmenopausal women with type 2 diabetes mellitus: a randomized crossover trial.

K. Morino, H. Maegawa, A. Kashiwagi, 2014, Metabolism: clinical and experimental.

Effects of a fish-based diet on the serum adiponectin concentration in young, non-obese, healthy Japanese subjects.

K. Morino, H. Maegawa, A. Kashiwagi, 2010, Journal of atherosclerosis and thrombosis.

Relation of the Expression of Transcriptional Factor TFAP2B to That of Adipokines in Subcutaneous and Omental Adipose Tissues

K. Morino, T. Uzu, H. Maegawa, 2010, Obesity.

Aging-Associated Reductions in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis

D. Befroy, G. Shulman, D. Hardie, 2007, Cell metabolism.

Use of MRI signal intensity of extraocular muscles to evaluate methylprednisolone pulse therapy in thyroid-associated ophthalmopathy

Y. Nishida, K. Morino, H. Maegawa, 2015, Japanese Journal of Ophthalmology.

Acute Effect of Metformin on Postprandial Hypertriglyceridemia through Delayed Gastric Emptying

K. Morino, H. Maegawa, Fumiaki Beppu, 2017, International journal of molecular sciences.

Metabolic Changes Induced by Dapagliflozin, an SGLT2 Inhibitor, in Japanese Patients with Type 2 Diabetes Treated by Oral Anti-diabetic Agents: A Randomized, Clinical Trial.

H. Arima, K. Morino, H. Maegawa, 2022, Diabetes research and clinical practice.

Glycemic control and number of natural teeth: analysis of cross-sectional Japanese employment-based dental insurance claims and medical check-up data

K. Morino, H. Maegawa, Takako Yasuda, 2021, Diabetology International.

Association between symptoms of bilateral numbness and/or paresthesia in the feet and postural instability in Japanese patients with diabetes

K. Morino, K. Nemoto, H. Maegawa, 2016, Diabetology International.

Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice.

M. Gillum, G. Shulman, G. Cline, 2006, Diabetes.

Nutrition and Periodontal Health in the Patients with Diabetes Mellitus: a Review from the Viewpoint of Endothelial Function

K. Morino, H. Maegawa, K. Kondo, 2021, Current Oral Health Reports.

Transcription factor AP-2beta: a negative regulator of IRS-1 gene expression.

K. Morino, H. Maegawa, A. Kashiwagi, 2010, Biochemical and biophysical research communications.

Transcription factor AP-2β inhibits expression and secretion of leptin, an insulin-sensitizing hormone, in 3T3-L1 adipocytes

K. Morino, H. Maegawa, A. Kashiwagi, 2010, International Journal of Obesity.

Fiber-rich diet with brown rice improves endothelial function in type 2 diabetes mellitus: A randomized controlled trial

H. Arima, K. Morino, K. Nemoto, 2017, PloS one.

A new antidiabetic agent (JTT-501) rapidly stimulates glucose disposal rates by enhancing insulin signal transduction in skeletal muscle

K. Morino, H. Maegawa, M. Haneda, 1999, Diabetologia.

Improved glucose metabolism by Eragrostis tef potentially through beige adipocyte formation and attenuating adipose tissue inflammation

K. Morino, T. Imamura, H. Maegawa, 2018, PloS one.

Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance*

G. Shulman, J. Geisler, G. Cline, 2007, Journal of Biological Chemistry.

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

G. Shulman, G. Cline, K. Morino, 2007, Diabetes.

Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet.

K. Morino, H. Maegawa, S. Kume, 2013, American journal of physiology. Endocrinology and metabolism.

Amla Enhances Mitochondrial Spare Respiratory Capacity by Increasing Mitochondrial Biogenesis and Antioxidant Systems in a Murine Skeletal Muscle Cell Line

K. Morino, H. Maegawa, Hirotaka Yamamoto, 2016, Oxidative medicine and cellular longevity.

Expression of a Dominant Negative SHP-2 in Transgenic Mice Induces Insulin Resistance*

K. Morino, H. Maegawa, M. Haneda, 1999, The Journal of Biological Chemistry.

Correction for Petersen et al., Effect of aging on muscle mitochondrial substrate utilization in humans

K. Petersen, S. Dufour, G. Shulman, 2015, Proceedings of the National Academy of Sciences.

Octreotide improves early dumping syndrome potentially through incretins: a case report.

K. Morino, H. Maegawa, K. Ikeda, 2013, Endocrine journal.

Transcription factor activating protein-2beta: a positive regulator of monocyte chemoattractant protein-1 gene expression.

K. Morino, H. Maegawa, A. Kashiwagi, 2009, Endocrinology.

SAFB1, an RBMX-binding protein, is a newly identified regulator of hepatic SREBP-1c gene.

K. Morino, H. Maegawa, A. Kashiwagi, 2009, BMB reports.

SAFB 1 , an RBMX-binding protein , is a newly identified regulator of hepatic SREBP-1 c gene

K. Morino, H. Maegawa, A. Kashiwagi, 2009 .

4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs.

K. Morino, K. Nemoto, H. Maegawa, 2014, Biochemical and biophysical research communications.

Insulin-induced c-Jun N-terminal kinase activation is negatively regulated by protein kinase C delta.

K. Morino, H. Maegawa, A. Kashiwagi, 2001, Endocrinology.

A simple and sensitive method for glutamine:fructose-6-phosphate amidotransferase assay.

K. Morino, H. Maegawa, Z. Shen, 2004, Journal of biochemical and biophysical methods.

Real-world evidence of the impact of obesity on residual teeth in the Japanese population: A cross-sectional study

K. Morino, I. Miyazawa, Kayo Harada, 2022, PloS one.

Ipragliflozin, a SGLT2 Inhibitor, Reduced Body Weight and Fat Mass but Not Muscle Mass in Japanese Type 2 Diabetic Patients Treated with Insulin—A Randomized Clinical Trial

H. Arima, K. Morino, H. Maegawa, 2018, Diabetes.

Geometry of Sleeve Gastrectomy Measured by 3D CT Versus Weight Loss: Preliminary Analysis

Y. Tomozawa, K. Morino, H. Maegawa, 2020, World Journal of Surgery.

Data set for renal sinus fat volume and visceral adipose tissue volume on computed tomography

T. Ohkubo, N. Nitta, Y. Nagatani, 2016, Data in brief.

Perivascular mechanical environment: A narrative review of the role of externally applied mechanical force in the pathogenesis of atherosclerosis

K. Morino, Takashi Yamaguchi, 2022, Frontiers in Cardiovascular Medicine.

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.

L. E. Hammond, R. Coleman, G. Shulman, 2005, Cell metabolism.

A case of local delayed-type allergy to zinc-containing insulin as a cause of diabetic ketoacidosis in a patient with type 1 diabetes mellitus undergoing continuous subcutaneous insulin infusion

K. Morino, K. Nemoto, H. Maegawa, 2016, Diabetology International.

Differential Association of Serum n-3 Polyunsaturated Fatty Acids with Various Cerebrovascular Lesions in Japanese Men

K. Nozaki, H. Arima, K. Morino, 2022, Cerebrovascular Diseases.

Protein-tyrosine Phosphatase-1B Negatively Regulates Insulin Signaling in L6 Myocytes and Fao Hepatoma Cells*

K. Morino, H. Maegawa, A. Kashiwagi, 2001, The Journal of Biological Chemistry.

A high-fiber, low-fat diet improves periodontal disease markers in high-risk subjects: a pilot study.

G. King, K. Morino, H. Maegawa, 2014, Nutrition research.

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation.

T. Horvath, G. Shulman, Xin-Yuan Fu, 2004, Proceedings of the National Academy of Sciences of the United States of America.

MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cells

K. Morino, T. Imamura, H. Maegawa, 2021, Scientific Reports.

MicroRNA-494 regulates mitochondrial biogenesis in skeletal muscle through mitochondrial transcription factor A and Forkhead box j3.

K. Morino, H. Maegawa, A. Kashiwagi, 2012, American journal of physiology. Endocrinology and metabolism.

Reversal of muscle insulin resistance by weight reduction in young, lean, insulin-resistant offspring of parents with type 2 diabetes

K. Petersen, S. Dufour, G. Shulman, 2012, Proceedings of the National Academy of Sciences.

Predictors for Mild and Severe Hypoglycemia in Insulin-Treated Japanese Diabetic Patients

K. Morino, K. Nemoto, H. Maegawa, 2015, PloS one.

Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine

K. Morino, H. Maegawa, E. Nishi, 2022, Molecular metabolism.

n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator–Activated Receptor-α–Dependent Manner

G. Shulman, G. Cline, K. Morino, 2007, Diabetes.

Postprandial activation of protein kinase Cµ regulates the expression of adipocytokines via the transcription factor AP-2β.

K. Morino, H. Maegawa, A. Kashiwagi, 2011, International journal of molecular medicine.

Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes.

K. Morino, H. Maegawa, A. Kashiwagi, 2013, Biochemical and biophysical research communications.

Liver fat accumulation assessed by computed tomography is an independent risk factor for diabetes mellitus in a population-based study: SESSA (Shiga Epidemiological Study of Subclinical Atherosclerosis).

K. Morino, H. Ueshima, H. Maegawa, 2020, Diabetes research and clinical practice.

Smoking status is associated with mild cognitive impairment assessed with the mini-mental state examination in Japanese diabetic patients

K. Morino, K. Nemoto, H. Maegawa, 2016, Diabetology International.

Association between attentional function and postural instability in Japanese older patients with diabetes mellitus

K. Morino, K. Nemoto, H. Maegawa, 2016, Diabetology International.

Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Hongyu Zhao, R. Eckel, Hong Wang, 2012, Diabetes.

Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

K. Morino, H. Maegawa, A. Kashiwagi, 2016, Diabetes & metabolism journal.

Preserving β-cell function is the major determinant of diabetes remission following laparoscopic sleeve gastrectomy in Japanese obese diabetic patients.

K. Morino, H. Maegawa, A. Kashiwagi, 2019, Endocrine journal.

Enhanced Intestinal Motility during Oral Glucose Tolerance Test after Laparoscopic Sleeve Gastrectomy: Preliminary Results Using Cine Magnetic Resonance Imaging

K. Morino, H. Maegawa, T. Tani, 2013, PloS one.

Duality of n-3 Polyunsaturated Fatty Acids on Mcp-1 Expression in Vascular Smooth Muscle: A Potential Role of 4-Hydroxy Hexenal

K. Morino, T. Imamura, H. Maegawa, 2015, Nutrients.

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

G. Shulman, M. White, K. Morino, 2008, Diabetes.

Ipragliflozin, a sodium–glucose cotransporter 2 inhibitor, reduces bodyweight and fat mass, but not muscle mass, in Japanese type 2 diabetes patients treated with insulin: A randomized clinical trial

K. Murata, H. Arima, K. Morino, 2019, Journal of diabetes investigation.

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

K. Petersen, S. Dufour, D. Befroy, 2005, The Journal of clinical investigation.

Mitochondrial Health in Aging and Age-Related Metabolic Disease

K. Morino, R. Acín-Pérez, David Sebastián, 2016, Oxidative medicine and cellular longevity.

Total energy expenditure is comparable between patients with and without diabetes mellitus: Clinical Evaluation of Energy Requirements in Patients with Diabetes Mellitus (CLEVER-DM) Study

K. Morino, Shigeho Tanaka, H. Maegawa, 2019, BMJ Open Diabetes Research & Care.

Diverse metabolic effects of O-GlcNAcylation in the pancreas but limited effects in insulin-sensitive organs in mice

K. Morino, H. Maegawa, S. Kume, 2017, Diabetologia.

N-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a PPARα-Dependent Manner

G. Shulman, G. Cline, K. Morino, 2007 .

Lack of O-GlcNAcylation enhances exercise-dependent glucose utilization potentially through AMP-activated protein kinase activation in skeletal muscle.

K. Morino, H. Maegawa, S. Kume, 2018, Biochemical and biophysical research communications.

Protein-tyrosine Phosphatase 1B as New Activator for Hepatic Lipogenesis via Sterol Regulatory Element-binding Protein-1 Gene Expression*

K. Morino, K. Nemoto, H. Maegawa, 2003, Journal of Biological Chemistry.

Renal sinus fat volume on computed tomography in middle-aged patients at risk for cardiovascular disease and its association with coronary artery calcification.

T. Ohkubo, N. Nitta, Y. Nagatani, 2016, Atherosclerosis.

Role of O‐linked N‐acetylglucosamine in the homeostasis of metabolic organs, and its potential links with diabetes and its complications

K. Morino, H. Maegawa, 2020, Journal of diabetes investigation.

Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells.

K. Morino, H. Maegawa, A. Kashiwagi, 2009, Atherosclerosis.

Mitochondrial ferritin affects mitochondria by stabilizing HIF-1α in retinal pigment epithelium: implications for the pathophysiology of age-related macular degeneration

D. Yanagisawa, I. Tooyama, K. Morino, 2016, Neurobiology of Aging.

Impact of obesity on annual medical expenditures and diabetes care in Japanese patients with type 2 diabetes mellitus

K. Morino, H. Maegawa, S. Kume, 2017, Journal of diabetes investigation.

Secular changes in clinical manifestations of kidney disease among Japanese adults with type 2 diabetes from 1996 to 2014

K. Morino, H. Maegawa, S. Kume, 2019, Journal of diabetes investigation.

Validity of the Use of a Triaxial Accelerometer and a Physical Activity Questionnaire for Estimating Total Energy Expenditure and Physical Activity Level among Elderly Patients with Type 2 Diabetes Mellitus: CLEVER-DM Study

K. Morino, Shigeho Tanaka, H. Maegawa, 2020, Annals of Nutrition and Metabolism.

MicroRNA-494 plays a role in fiber type-specific skeletal myogenesis in human induced pluripotent stem cells.

K. Morino, T. Imamura, H. Maegawa, 2015, Biochemical and biophysical research communications.

MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes

K. Morino, T. Imamura, H. Maegawa, 2018, Scientific Reports.

Annual trends in glycemic control and prescribing patterns in diabetic treatment according to age in Japanese patients with type 2 diabetes between 2012 and 2019 (JDDM XX).

K. Morino, H. Yokoyama, H. Maegawa, 2023, Diabetes research and clinical practice.

MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes

K. Morino, T. Imamura, H. Maegawa, 2018, Scientific Reports.

Predictors for Mild and Severe Hypoglycemia in Insulin-Treated Japanese Diabetic Patients

K. Morino, H. Maegawa, S. Ugi, 2015, PloS one.

Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

K. Petersen, G. Shulman, K. Morino, 2006, Diabetes.

Efficacy of metformin on postprandial plasma triglyceride concentration by administration timing in patients with type 2 diabetes mellitus: A randomized cross‐over pilot study

K. Morino, H. Maegawa, S. Ugi, 2019, Journal of diabetes investigation.

Nutritional and metabolic control of germ cell fate through O‐GlcNAc regulation

K. Morino, H. Maegawa, Asuka Takehara, 2023, EMBO reports.