J. Yang

发表

Comparison of SUV and Patlak slope for monitoring of cancer therapy using serial PET scans

S. Libutti, S. Bacharach, N. Freedman, 2002, European Journal of Nuclear Medicine and Molecular Imaging.

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

F. Marincola, S. Rosenberg, P. Hwu, 1998, Nature Medicine.

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.

S. Rosenberg, R. Morgan, J. Yang, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis.

M. Merino, S. Rosenberg, R. Morgan, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

M. Raffeld, P. Duray, S. Rosenberg, 2002, Science.

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

S. Rosenberg, R. Morgan, J. Yang, 2008, Nature Reviews Cancer.

Toxicities of Immunotherapy for the Practitioner.

M. Atkins, J. Yang, J. Weber, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Different Adjuvanticity of Incomplete Freund's Adjuvant Derived From Beef or Vegetable Components in Melanoma Patients Immunized With a Peptide Vaccine

S. Rosenberg, J. Yang, N. Restifo, 2010, Journal of immunotherapy.

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

S. Rosenberg, J. Yang, S. Turcotte, 2014, Science.

Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes

S. Rosenberg, R. Morgan, J. Yang, 2006, Science.

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens.

S. Rosenberg, D. Citrin, J. Yang, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

S. Steinberg, S. Rosenberg, D. Citrin, 2011, Clinical Cancer Research.

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

S. Steinberg, S. Rosenberg, D. Citrin, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Melanoma: Why is sentinel lymph node biopsy 'standard of care' for melanoma?

S. Rosenberg, J. Yang, R. Sherry, 2014, Nature Reviews Clinical Oncology.

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

M. Merino, S. Rosenberg, R. Morgan, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

Tongguang Wang, Dolores J. Schendel, Richard A. Morgan, 2013, Journal of immunotherapy.

Landscape of Tumor Antigens in T Cell Immunotherapy

S. Ilyas, J. Yang, Sadia Ilyas, 2015, The Journal of Immunology.

Pretreatment epidermal growth factor receptor (EGFR) T790M mutation predicts shorter EGFR tyrosine kinase inhibitor response duration in patients with non-small-cell lung cancer.

Sung-Liang Yu, Ker-Chau Li, Min-Liang Kuo, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.

Seth M Steinberg, S. Steinberg, Helen X. Chen, 2003, The New England journal of medicine.

MISSION Trial - A phase III, multi-center, placebo-controlled trial of sorafenib in patients with relapsed or refractory predominantly non-squamous NSCLC after 2 or 3 previous treatment regimens.

H. Wakelee, E. Smit, T. Mok, 2015, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Cancer immunotherapy: moving beyond current vaccines

S. Rosenberg, J. Yang, N. Restifo, 2004, Nature Medicine.

Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma

S. Steinberg, S. Rosenberg, J. Yang, 2005, The Journal of Immunology.

First‐Line Afatinib versus Chemotherapy in Patients with Non–Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases

L. Sequist, K. O'Byrne, T. Mok, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Outcomes of Adoptive Cell Transfer With Tumor-infiltrating Lymphocytes for Metastatic Melanoma Patients With and Without Brain Metastases

S. Rosenberg, J. Butman, J. Yang, 2018, Journal of immunotherapy.

A Phase I Study of Nonmyeloablative Chemotherapy and Adoptive Transfer of Autologous Tumor Antigen-Specific T Lymphocytes in Patients With Metastatic Melanoma

F. Marincola, S. Rosenberg, P. Hwu, 2002, Journal of immunotherapy.

Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma.

S. Rosenberg, P. Hwu, J. Yang, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

CD8+ Enriched “Young” Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma

S. Rosenberg, D. Citrin, J. Yang, 2010, Clinical Cancer Research.

Abstract LB-175: Tumor regression in patients with metastatic synovial sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

S. Rosenberg, R. Morgan, J. Yang, 2010 .

Vaccine-Stimulated, Adoptively Transferred CD8+ T Cells Traffic Indiscriminately and Ubiquitously while Mediating Specific Tumor Destruction1

C. Klebanoff, J. Yang, N. Restifo, 2004, The Journal of Immunology.

Identification of Tyrosinase-related Protein 2 as a Tumor Rejection Antigen for the B16 Melanoma

S. Rosenberg, J. Yang, P. Robbins, 1997, The Journal of experimental medicine.

Novel EGFR Inhibitors in Non-small Cell Lung Cancer: Current Status of Afatinib

J. Yang, Chia‐Chi Lin, Bin-Chi Liao, 2017, Current Oncology Reports.

Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4.

S. Rosenberg, J. Yang, A. Maker, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Adoptive Transfer of Cloned Melanoma-Reactive T Lymphocytes for the Treatment of Patients with Metastatic Melanoma

F. Marincola, S. Rosenberg, P. Hwu, 2001, Journal of immunotherapy.

Immunization against Endogenous Retroviral Tumor-associated Antigens 1

Willem, P. Hwu, J. Yang, 2001 .

Immunization of Patients with Metastatic Melanoma Using Both Class I- and Class II-Restricted Peptides from Melanoma-Associated Antigens

S. Rosenberg, P. Hwu, J. Yang, 2003, Journal of immunotherapy.

Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen.

S. Rosenberg, P. Hwu, J. Yang, 2003, Human gene therapy.

Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis.

S. Rosenberg, K. Csaky, J. Yang, 2004, Journal of immunotherapy.

Immunization of HLA-A*0201 and/or HLA-DPβ1*04 Patients with Metastatic Melanoma Using Epitopes from the NY-ESO-1 Antigen

S. Rosenberg, J. Yang, S. Topalian, 2004, Journal of immunotherapy.

Anti-CD19 CAR T Cells Administered after Low-Dose Chemotherapy Can Induce Remissions of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma

S. Rosenberg, C. Klebanoff, J. Yang, 2014 .

Bevacizumab in EGFR-positive NSCLC: time to change first-line treatment?

J. Yang, 2019, The Lancet. Oncology.

Predictive value of PD-L1 and other clinical factors for chemoimmunotherapy in advanced non-small-cell lung cancer.

I. Marschner, T. Mok, J. Yang, 2019, Future Oncology.

Plasma ctDNA Analysis for Detection of the EGFR T790M Mutation in Patients with Advanced Non–Small Cell Lung Cancer

P. Jänne, T. Mitsudomi, S. Ramalingam, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers.

J. Gartner, S. Rosenberg, J. Yang, 2022, Cancer cell.

Immunotherapy for renal cell cancer.

J. Yang, R. Childs, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers

J. Yang, N. Restifo, Zhiya Yu, 2016, Clinical Cancer Research.

Study on Adoptive Immunotherapy Using Gene-Modified TCells for Ovarian Cancer

S. Rosenberg, P. Hwu, S. Canevari, 2006 .

A T cell-independent antitumor response in mice with bone marrow cells retrovirally transduced with an antibody/Fc-γ chain chimeric receptor gene recognizing a human ovarian cancer antigen

S. Rosenberg, P. Hwu, J. Yang, 1998, Nature Medicine.

Audiovestibular Dysfunction Associated with Adoptive Cell Immunotherapy for Melanoma

S. Rosenberg, C. Van Waes, R. Morgan, 2011, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

regression and targets normal tissues expressing cognate antigen Gene therapy with human and mouse T-cell receptors mediates cancer

S. Rosenberg, Alexandria P. Cogdill, R. Morgan, 2009 .

Ipilimumab (Anti-CTLA4 Antibody) Causes Regression of Metastatic Renal Cell Cancer Associated With Enteritis and Hypophysitis

S. Rosenberg, I. Lowy, J. Yang, 2007, Journal of immunotherapy.

Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.

S. Rosenberg, J. Yang, R. Sherry, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cranial Irradiation for Patients with Epidermal Growth Factor Receptor (EGFR) Mutant Lung Cancer Who Have Brain Metastases in the Era of a New Generation of EGFR Inhibitors.

Jih-Hsiang Lee, J. Shih, Hsuan-Yu Chen, 2019, The oncologist.

Safety and efficacy of INC280 in combination with gefitinib (gef) in patients with EGFR-mutated (mut), MET-positive NSCLC: A single-arm phase lb/ll study.

M. Ahn, Yi-long Wu, E. Felip, 2014 .

Afatinib for the Treatment of Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations: An Updated Database of 1023 Cases Brief Report

Edward S. Kim, Keunchil Park, F. de Marinis, 2022, Frontiers in Oncology.

Amivantamab in EGFR Exon 20 Insertion–Mutated Non–Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study

N. Girard, R. Govindan, Keunchil Park, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

EGFR Mutation Analysis for Prospective Patient Selection in Two Phase II Registration Studies of Osimertinib

P. Jänne, F. Shepherd, J. Yang, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Activity and safety of AZD3759 in EGFR-mutant non-small-cell lung cancer with CNS metastases (BLOOM): a phase 1, open-label, dose-escalation and dose-expansion study.

J. Ahn, M. Ahn, Dong-Wan Kim, 2017, The Lancet. Respiratory medicine.

AZD3759, a BBB-penetrating EGFR inhibitor for the treatment of EGFR mutant NSCLC with CNS metastases

M. Ahn, Dong-Wan Kim, J. Yang, 2016, Science Translational Medicine.

Coexistence of EGFR T790M mutation and common activating mutations in pretreatment non-small cell lung cancer: A systematic review and meta-analysis.

J. Shih, R. Rosell, Pan‐Chyr Yang, 2016, Lung cancer.

Tumor Infiltrating Lymphocyte Therapy for Metastatic Melanoma: Analysis of Tumors Resected for TIL

S. Steinberg, S. Rosenberg, J. Yang, 2010, Journal of immunotherapy.

Tumor Regression and Autoimmunity in Patients Treated With Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Interleukin 2: A Phase I/II Study

S. Rosenberg, J. Yang, A. Maker, 2005, Annals of Surgical Oncology.

Treatment of metastatic uveal melanoma with adoptive transfer of tumour-infiltrating lymphocytes: a single-centre, two-stage, single-arm, phase 2 study.

A. K. Srivastava, M. Raffeld, S. Rosenberg, 2017, The Lancet. Oncology.

Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4.

A. Feldman, S. Rosenberg, I. Lowy, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Benefits and limitations of real-world evidence: lessons from EGFR mutation-positive non-small-cell lung cancer.

T. Owonikoko, J. Yang, Bassel Nazha, 2020, Future oncology.

Effective Treatment Of Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma With Autologous T Cells Genetically-Engineered To Express An Anti-CD19 Chimeric Antigen Receptor

Sadik H. Kassim, S. Rosenberg, J. Yang, 2013 .

A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors

G. Shapiro, E. Kwak, J. Yang, 2014, Investigational New Drugs.

A Review of Regimens Combining Pemetrexed With an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in the Treatment of Advanced Nonsquamous Non–Small‐Cell Lung Cancer

Keunchil Park, B. Han, T. Mok, 2018, Clinical lung cancer.

Clinical activity of the mutant-selective EGFR inhibitor AZD9291 in patients (pts) with EGFR inhibitor–resistant non-small cell lung cancer (NSCLC).

P. Jänne, M. Ranson, M. Ahn, 2014 .

Survival of Patients with Small Cell Lung Carcinoma in Taiwan

M. Lai, J. Yang, W. Shau, 2012, Oncology.

INSPIRE: A phase III study of the BLP25 liposome vaccine (L-BLP25) in Asian patients with unresectable stage III non-small cell lung cancer

Keunchil Park, T. Mok, Yi-long Wu, 2011, BMC Cancer.

Small-cell lung cancer treatment: where is the target?

J. Yang, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Successful Treatment of Melanoma Brain Metastases with Adoptive Cell Therapy

S. Rosenberg, J. Butman, J. Yang, 2010, Clinical Cancer Research.

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells.

W. Wilson, S. Rosenberg, R. Morgan, 2012, Blood.

Adoptive cell therapy targeting common p53 neoantigens in human solid cancers

Chuong D. Hoang, C. Hoang, J. Gartner, 2021 .

The adoptive transfer of cultured T cells for patients with metastatic melanoma.

J. Yang, 2013, Clinics in dermatology.

Experience with the Use of High‐Dose Interleukin‐2 in the Treatment of 652 Cancer Patients

W. Linehan, S. Rosenberg, M. Lotze, 1989, Annals of surgery.

PD-L1 expression as a prognostic marker in patients treated with chemotherapy for metastatic non-small-cell lung cancer.

I. Marschner, J. Yang, W. Cooper, 2022, Future oncology.

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor.

Sadik H. Kassim, M. Raffeld, S. Rosenberg, 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Persistence of CTL Clones Targeting Melanocyte Differentiation Antigens Was Insufficient to Mediate Significant Melanoma Regression in Humans

A. K. Srivastava, S. Rosenberg, J. Yang, 2014, Clinical Cancer Research.

Distinctive features of the differentiated phenotype and infiltration of tumor-reactive lymphocytes in clear cell renal cell carcinoma.

J. Yang, P. Robbins, K. Hanada, 2012, Cancer research.

Development of a genetically-modified novel T-cell receptor for adoptive cell transfer against renal cell carcinoma.

J. Yang, S. Feldman, Yangbing Zhao, 2011, Journal of immunological methods.

Destruction TumorUbiquitously while Mediating Specific T Cells Traffic Indiscriminately and + CD 8 Vaccine-Stimulated , Adoptively Transferred

C. Klebanoff, J. Yang, N. Restifo, 2004 .

Impact of Prior Treatment on the Efficacy of Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma

S. Rosenberg, J. Yang, D. White, 2021, Clinical Cancer Research.

Treatment of metastatic uveal melanoma with adoptive transfer of tumor infiltrating lymphocytes: a single-center phase 2 study

A. K. Srivastava, M. Raffeld, S. Rosenberg, 2017 .

Adoptive T-Cell Therapy for Cancer.

S. Rosenberg, J. Yang, 2016, Advances in immunology.

Melanoma vaccines.

J. Yang, 2011, Cancer journal.

Assessment of Ovarian Function After Preparative Chemotherapy and Total Body Radiation for Adoptive Cell Therapy

S. Rosenberg, J. Yang, D. White, 2011, Journal of immunotherapy.

Selection of CD8+PD-1+ Lymphocytes in Fresh Human Melanomas Enriches for Tumor-reactive T Cells

S. Rosenberg, J. Yang, J. Wunderlich, 2010, Journal of immunotherapy.

T-Cell Receptor Gene Therapy for Human Papillomavirus–Associated Epithelial Cancers: A First-in-Human, Phase I/II Study

J. Gartner, S. Rosenberg, S. Hewitt, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The ongoing mystery of renal cell cancer

J. Yang, 2021, Cell reports. Medicine.

Tepotinib plus gefitinib in patients with EGFR-mutant non-small-cell lung cancer with MET overexpression or MET amplification and acquired resistance to previous EGFR inhibitor (INSIGHT study): an open-label, phase 1b/2, multicentre, randomised trial.

Ying Cheng, Keunchil Park, Yi-long Wu, 2020, The Lancet. Respiratory medicine.

First-line afatinib for advanced EGFRm+ NSCLC: Analysis of long-term responders in the LUX-Lung 3, 6, and 7 trials.

L. Sequist, Keunchil Park, Yi-long Wu, 2019, Lung cancer.

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials.

L. Sequist, K. O'Byrne, T. Mok, 2015, The Lancet. Oncology.

Pemetrexed Continuation Maintenance in Patients with Nonsquamous Non-small Cell Lung Cancer: Review of Two East Asian Trials in Reference to PARAMOUNT

M. Ahn, J. Yang, R. Cheng, 2014, Cancer research and treatment : official journal of Korean Cancer Association.

Reply to A. Ota et al, Y.H. Kim, and N. Van Der Steen et al.

J. Yang, M. Orlando, T. Puri, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tumor PD-L1 Expression and Clinical Outcomes in Advanced-stage Non-Small Cell Lung Cancer Patients Treated with Nivolumab or Pembrolizumab: Real-World Data in Taiwan

Jih-Hsiang Lee, Yih-Leong Chang, J. Shih, 2018, Journal of Cancer.

Maximizing Benefits from Maintenance Pemetrexed with Stereotactic Ablative Radiotherapy in Oligoprogressive Non-Squamous Non-Small Cell Lung Cancer

J. Yang, J. Cheng, Kuan-Yu Chen, 2016, Case Reports in Oncology.

Best Response According to RECIST During First‐line EGFR‐TKI Treatment Predicts Survival in EGFR Mutation‐positive Non–Small‐cell Lung Cancer Patients

Jih-Hsiang Lee, J. Shih, J. Yang, 2018, Clinical lung cancer.

Enhancer Remodeling and MicroRNA Alterations Are Associated with Acquired Resistance to ALK Inhibitors.

You Won Lee, Jae Woo Choi, J. Shih, 2018, Cancer research.

Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours

Jie Yang, Jih-Hsiang Lee, N. Strelkowa, 2020, British Journal of Cancer.

Activity of Afatinib in Heavily Pretreated Patients With ERBB2 Mutation–Positive Advanced NSCLC: Findings From a Global Named Patient Use Program

J. Shih, S. Peters, G. Chang, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer

R. Govindan, A. Dingemans, A. Shaw, 2017, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A Phase II Study of Tumor-infiltrating Lymphocyte Therapy for Human Papillomavirus–associated Epithelial Cancers

S. Rosenberg, C. Klebanoff, J. Yang, 2018, Clinical Cancer Research.

Durable remissions in two adult patients with Burkitt lymphoma following anti-CD19 CAR T-cell therapy: a single center experience

S. Rosenberg, J. Yang, M. Ahlman, 2022, Leukemia & lymphoma.

Real-World or Controlled Clinical Trial Data in Real-World Practice.

J. Yang, Ting-Hui Wu, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Erratum: Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer (J Natl Cancer Inst (1993) 85 (622-632))

S. Rosenberg, M. Lotze, J. Yang, 1993 .

Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer.

S. Rosenberg, J. Yang, S. Topalian, 2005, Journal of immunotherapy.

Viruses Encoding the Anchor-modified gp 100 Melanoma Antigen Can Generate Antitumor Immune Responses in Patients with Metastatic Melanoma

S. Rosenberg, P. Hwu, J. Yang, 2003 .

Prognostic factors and treatment outcomes of malignant pleural mesothelioma in Eastern Asian patients - A Taiwanese study.

T. Chen, J. Yang, L. Lee, 2019, Journal of the Formosan Medical Association = Taiwan yi zhi.

An antigenic peptide produced by reverse splicing and double asparagine deamidation

S. Rosenberg, J. Yang, P. Robbins, 2011, Proceedings of the National Academy of Sciences.

A phase I study of pexidartinib, a colony-stimulating factor 1 receptor inhibitor, in Asian patients with advanced solid tumors

Jih-Hsiang Lee, T. Chen, J. Yang, 2019, Investigational New Drugs.

Primary analysis of a randomized, double-blind, phase II study of the anti-TIGIT antibody tiragolumab (tira) plus atezolizumab (atezo) versus placebo plus atezo as first-line (1L) treatment in patients with PD-L1-selected NSCLC (CITYSCAPE).

Robert W. Hsieh, Melissa L. Johnson, L. Paz-Ares, 2020 .

KEYNOTE-604: Pembrolizumab (pembro) or placebo plus etoposide and platinum (EP) as first-line therapy for extensive-stage (ES) small-cell lung cancer (SCLC).

C. Rudin, S. Peters, A. Navarro, 2020 .

Tiragolumab plus atezolizumab versus placebo plus atezolizumab as a first-line treatment for PD-L1-selected non-small-cell lung cancer (CITYSCAPE): primary and follow-up analyses of a randomised, double-blind, phase 2 study.

Robert W. Hsieh, Melissa L. Johnson, J. Yang, 2022, The Lancet. Oncology.

Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)

Ping Wang, Ying Cheng, C. Chiu, 2020 .

Osimertinib in Patients With Epidermal Growth Factor Receptor Mutation–Positive Non–Small-Cell Lung Cancer and Leptomeningeal Metastases: The BLOOM Study

J. Ahn, M. Ahn, Dong-Wan Kim, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

PLS. plenary session

C. Obasaju, C. Gridelli, L. Sequist, 2012 .

Neoantigen Identification and Response to Adoptive Cell Transfer in anti PD-1 Naïve and Experienced Patients with Metastatic Melanoma.

J. Gartner, S. Sindiri, S. Rosenberg, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

TNF/TIL Human Gene Therapy Clinical Protocol: Original Protocol, April 23, 1990

W. Anderson, J. Yang, Y. Chiang, 1990 .

IL-17 Secreted by Tumor Reactive T Cells Induces IL-8 Release by Human Renal Cancer Cells

J. Yang, K. Hanada, Qiong J. Wang, 2009, Journal of immunotherapy.

Rapid production of clinical-grade gammaretroviral vectors in expanded surface roller bottles using a "modified" step-filtration process for clearance of packaging cells.

K. Cornetta, S. Rosenberg, R. Morgan, 2011, Human gene therapy.

Characterization of a Novel Nonclassical T Cell Clone with Broad Reactivity against Human Renal Cell Carcinomas1

J. Yang, K. Hanada, Qiong J. Wang, 2008, The Journal of Immunology.

190 Patient-derived tumor organoids reveal mechanisms of immune evasion which can guide decisions in adoptive cell therapy for common epithelial cancers

S. Rosenberg, J. Yang, M. Parkhurst, 2021, Journal for ImmunoTherapy of Cancer.

Anti-CD19 chimeric antigen receptor T cells preceded by low-dose chemotherapy to induce remissions of advanced lymphoma.

J. Friedberg, S. Rosenberg, C. Klebanoff, 2016 .

Induction of CD4(+) T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells.

P. Hwu, J. Yang, Helen Y Wang, 2002, The Journal of clinical investigation.

Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for interleukin-2.

W. Linehan, P. Hwu, J. Mulé, 1992, Human gene therapy.

Immunization of cancer patients using autologous cancer cells modified by insertion of the gene for tumor necrosis factor.

A. Asher, W. Linehan, P. Hwu, 1992, Human gene therapy.

Safety and Efficacy of High-Dose Interleukin-2 Therapy in Patients With Brain Metastases

S. Steinberg, S. Rosenberg, J. Yang, 2002, Journal of immunotherapy.

Durability of Complete Responses in Patients With Metastatic Cancer Treated With High-Dose Interleukin-2. Identification of the Antigens Mediating Response

S. Steinberg, S. Rosenberg, J. Yang, 1999 .

Melanoma Tumor‐Infiltrating Lymphocytes Derived from Four Distinct Anatomic Sites Obtained from a Single Patient: Comparison of Functional Reactivity and Melanoma Antigen Recognition

M. Nishimura, J. Yang, P. Robbins, 1995, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

The use of polyethylene glycol‐modified interleukin‐2 (PEG‐IL‐2) in the treatment of patients with metastatic renal cell carcinoma and melanoma

F. Marincola, S. Rosenberg, J. Yang, 1995, Cancer.

Antitumor Efficacy Demonstrate Superior In Vitro and In Vivo High Avidity CTLs for Two Self-Antigens

S. Rosenberg, J. Yang, H. Zeh, 1998 .

Randomized S tudy o f H igh-Dose a nd L ow-Dose I nterleukin-2 in P atients W ith M etastatic R enal C ancer

S. Steinberg, M. Merino, S. Rosenberg, 2003 .

Surgical resection of metastatic renal cell carcinoma and melanoma after response to interleukin‐2‐based immunotherapy

H. Pass, S. Rosenberg, J. Yang, 1992, Cancer.

Avelumab vs docetaxel in patients with platinum-treated advanced non-small-cell lung cancer: 2-year follow-up from the JAVELIN Lung 200 phase 3 trial.

Keunchil Park, F. de Marinis, M. Krzakowski, 2021, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

24‐Month Overall Survival from KEYNOTE‐021 Cohort G: Pemetrexed and Carboplatin with or without Pembrolizumab as First‐Line Therapy for Advanced Nonsquamous Non–Small Cell Lung Cancer

L. Sequist, H. Borghaei, S. Jalal, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Estimating and Interpreting the Overall Survival Benefit of Checkpoint Inhibitors via Meta-analysis-Reply.

V. Gebski, J. Yang, Chee Khoon Lee, 2018, JAMA oncology.

Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 Cohorts A and C.

L. Sequist, H. Borghaei, A. Patnaik, 2015 .

Human Renal Cell Carcinomas Cell Clone with Broad Reactivity against Characterization of a Novel Nonclassical T

J. Yang, K. Hanada, Qiong J. Wang, 2008 .

Clinical utility of plasma EGFR mutation detection with quantitative PCR in advanced lung cancer: A meta-analysis.

T. Mok, Yi-long Wu, K. Goto, 2021, Lung cancer.

MSLT-I—response of clinical trial investigators

J. Yang, R. Sherry, 2014, Nature Reviews Clinical Oncology.

A Prospective Randomized Trial Evaluating Colloid Versus Crystalloid Resuscitation in the Treatment of the Vascular Leak Syndrome Associated with Interleukin‐2 Therapy

S. Steinberg, S. Rosenberg, M. Lotze, 1994, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

S. Rosenberg, I. Lowy, J. Yang, 2010, Journal of immunotherapy.

Phase II Study of Crizotinib in East Asian Patients With ROS1-Positive Advanced Non-Small-Cell Lung Cancer.

T. Yamanaka, M. Ahn, Yi-long Wu, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Osimertinib for patients (pts) with leptomeningeal metastases (LM) from EGFR-mutant non-small cell lung cancer (NSCLC): Updated results from the BLOOM study.

M. Ahn, Dong-Wan Kim, J. Yang, 2017 .

The hematologic toxicity of interleukin‐2 in patients with metastatic melanoma and renal cell carcinoma

S. Rosenberg, J. Yang, D. White, 1995, Cancer.

for Combination Metastatic Colorectal Cancer Using 5Fluorouracil, Leucovorin and Interleukin-2

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Keunchil Park, J. Vansteenkiste, J. Yang, 2021, Lung cancer.

Phase I Study of the Efficacy and Safety of Ramucirumab in Combination with Osimertinib in Advanced T790M-positive EGFR-mutant Non–small Cell Lung Cancer

Keunchil Park, D. Planchard, L. Paz-Ares, 2020, Clinical Cancer Research.

Clinical outcomes and toxicity predictors of thoracic re-irradiation for locoregionally recurrent lung cancer

J. Shih, J. Yang, A. Cheng, 2018, Clinical and translational radiation oncology.

Clinical outcomes and secondary epidermal growth factor receptor (EGFR) T790M mutation among first‐line gefitinib, erlotinib and afatinib‐treated non‐small cell lung cancer patients with activating EGFR mutations

Jih-Hsiang Lee, J. Shih, J. Yang, 2019, International journal of cancer.

First-line afatinib vs gefitinib for patients with EGFR mutation-positive NSCLC (LUX-Lung 7): impact of afatinib dose adjustment and analysis of mode of initial progression for patients who continued treatment beyond progression

K. O'Byrne, Keunchil Park, T. Mok, 2019, Journal of Cancer Research and Clinical Oncology.

Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non-small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study.

L. Sequist, H. Borghaei, A. Patnaik, 2018, Lung cancer.

Sequencing of therapy following first-line afatinib in patients with EGFR mutation-positive non-small cell lung cancer.

K. O'Byrne, Keunchil Park, T. Mok, 2019, Lung cancer.

Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer.

Thomas John, Aleksandra, Aleksandra Markovets, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

V. Gebski, I. Marschner, T. Mitsudomi, 2017, Journal of the National Cancer Institute.

Genetic Modifiers of Progression‐Free Survival in Never‐Smoking Lung Adenocarcinoma Patients Treated with First‐Line Tyrosine Kinase Inhibitors

Jih-Hsiang Lee, Chien-Jen Chen, N. Rothman, 2017, American journal of respiratory and critical care medicine.

Comparative effectiveness of first-line platinum-based chemotherapy regimens for advanced lung squamous cell carcinoma.

M. Lai, J. Yang, A. Cheng, 2015, Clinical lung cancer.

First-Line Management of EGFR-Mutated Advanced Lung Adenocarcinoma: Recent Developments

J. Yang, Chia‐Chi Lin, Bin-Chi Liao, 2013, Drugs.

Comparison of gefitinib and erlotinib efficacies as third-line therapy for advanced non-small-cell lung cancer.

M. Lai, J. Yang, W. Shau, 2013, European journal of cancer.

Driver mutations of young lung adenocarcinoma patients with malignant pleural effusion

J. Shih, J. Yang, Yi-nan Liu, 2018, Genes, chromosomes & cancer.

EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6

L. Sequist, K. O'Byrne, T. Mok, 2016, British Journal of Cancer.

Asian Thoracic Oncology Research Group expert consensus statement on optimal management of stage III non-small cell lung cancer.

M. Ahn, T. Mok, H. Onishi, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Serial Plasma Cell-Free Circulating Tumor DNA Tests Identify Genomic Alterations for Early Prediction of Osimertinib Treatment Outcome in EGFR T790M–Positive NSCLC

Jih-Hsiang Lee, J. Shih, J. Yang, 2020, JTO clinical and research reports.

Safety of gefitinib in non-small cell lung cancer treatment

Jih-Hsiang Lee, J. Yang, Chia‐Chi Lin, 2016, Expert opinion on drug safety.

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for Non–Small-Cell Lung Cancer Patients with Leptomeningeal Carcinomatosis

Jih-Hsiang Lee, J. Shih, J. Yang, 2015, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Bcl-2-Like Protein 11 Deletion Polymorphism Predicts Survival in Advanced Non–Small-Cell Lung Cancer

Jih-Hsiang Lee, J. Shih, Yeun-Chung Chang, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Polo-like Kinase 1 Inhibitors and Their Potential Role in Anticancer Therapy, with a Focus on NSCLC

R. Medema, J. Yang, Chia‐Chi Lin, 2011, Clinical Cancer Research.

BiomarkerAnalysesandFinalOverallSurvivalResultsFroma PhaseIII,Randomized,Open-Label,First-LineStudyofGefitinib VersusCarboplatin/PaclitaxelinClinicallySelectedPatientsWith AdvancedNon-Small-CellLungCancerinAsia(IPASS)

T. Mok, Yi-long Wu, S. Thongprasert, 2011 .

Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib with Chemotherapy (LUX-Lung 3 and LUX-Lung 6)

L. Sequist, K. O'Byrne, T. Mok, 2017, The Patient - Patient-Centered Outcomes Research.

Profile of the therascreen® EGFR RGQ PCR kit as a companion diagnostic for gefitinib in non-small cell lung cancer

Jih-Hsiang Lee, J. Yang, Chia‐Chi Lin, 2016, Expert review of molecular diagnostics.

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the ‘real-world’ clinical setting

Keunchil Park, J. Yang, I. Okamoto, 2019, Therapeutic advances in medical oncology.

The Value of Early Depth of Response in Predicting Long‐Term Outcome in EGFR‐Mutant Lung Cancer

V. Gebski, I. Marschner, L. Sequist, 2018, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Treating brain metastases in non-small cell lung cancer patients: what have we learnt from pharmaceutical recent clinical trials?

J. Yang, Chia‐Chi Lin, Bin-Chi Liao, 2018, Expert opinion on pharmacotherapy.

Randomized Phase II Trial of Gefitinib With and Without Pemetrexed as First-Line Therapy in Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer With Activating Epidermal Growth Factor Receptor Mutations.

Ying Cheng, Pan‐Chyr Yang, J. Yang, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cytotoxic Chemotherapy as First-Line Therapy for Advanced Non-Small-Cell Lung Cancer in Taiwan: Daily Practice

M. Lai, J. Yang, A. Cheng, 2016, Journal of Cancer.

Epidermal growth factor receptor mutation analysis in previously unanalyzed histology samples and cytology samples from the phase III Iressa Pan-ASia Study (IPASS).

T. Mok, Yi-long Wu, N. Saijo, 2014, Lung cancer.

Front-line erlotinib in unselected patient with advanced NSCLC followed by standard chemotherapy with gemcitabine and cisplatin - TORCH study.

J. Yang, Bin-Chi Liao, 2012, Translational lung cancer research.

Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels.

J. Friedberg, S. Rosenberg, C. Klebanoff, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Adjusted Indirect Comparison Using Propensity Score Matching of Osimertinib to Platinum-Based Doublet Chemotherapy in Patients with EGFRm T790M NSCLC Who Have Progressed after EGFR-TKI

T. Mitsudomi, T. Mok, J. Yang, 2017, Clinical Drug Investigation.

Phase 2 Trial of Linifanib (ABT-869) in Patients with Advanced Non-small Cell Lung Cancer

N. Hanna, D. Gandara, R. Salgia, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

αβ T cell receptors that do not undergo major histocompatibility complex-specific thymic selection possess antibody-like recognition specificities.

A. Singer, Jinghua Lu, P. Sun, 2012, Immunity.

Genetic Polymorphism of XRCC1 Arg399Gln Is Associated With Survival in Non–Small-Cell Lung Cancer Patients Treated With Gemcitabine/Platinum

J. Shih, Yuh-Min Chen, G. Chang, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Efficacy of Adjuvant Radiation Therapy in the Treatment of Soft Tissue Sarcoma of the Extremity: 20-year Follow-Up of a Randomized Prospective Trial

S. Steinberg, S. Rosenberg, J. Yang, 2014, Annals of Surgical Oncology.

Intrapatient Dose Escalation of Anti–CTLA-4 Antibody in Patients With Metastatic Melanoma

S. Rosenberg, J. Yang, A. Maker, 2006, Journal of immunotherapy.

Cytotoxic T lymphocyte-associated antigen 4 blockade with ipilimumab: Long-term follow-up of 179 patients with metastatic melanoma.

S. Rosenberg, J. Yang, D. White, 2010 .

High‐dose interleukin‐2 for the treatment of metastatic renal cell carcinoma

S. Steinberg, S. Rosenberg, J. Yang, 2008, Cancer.

Correlation of baseline molecular and clinical variables with ALK inhibitor efficacy in ALTA-1L.

M. Ahn, D. Camidge, Geoffrey Liu, 2020 .

Adoptive T-cell Transfer Therapy and Oncogene-Targeted Therapy for Melanoma: The Search for Synergy

B. Neyns, J. Yang, M. L. Kwong, 2013, Clinical Cancer Research.

Phosphorylated insulin-like growth factor-1 receptor (pIGF1R) is a poor prognostic factor in brain metastases from lung adenocarcinomas

J. Shih, J. Yang, A. Cheng, 2013, Journal of Neuro-Oncology.

Survival following surgery with or without adjuvant chemotherapy for stage I-IIIA non-small cell lung cancer: an east asian population-based study.

M. Lai, J. Yang, W. Shau, 2012, The oncologist.

Tumor-Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma

Sadik H. Kassim, S. Rosenberg, R. Morgan, 2015, Clinical Cancer Research.

Toxicities Associated With Adoptive T-Cell Transfer for Cancer.

J. Yang, James C Yang, 2015, Cancer journal.

Sequential treatment with afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: an observational study.

B. Halmos, J. Yang, T. Čufer, 2018, Future oncology.

Molecular identification of an MHC-independent ligand recognized by a human {alpha}/{beta} T-cell receptor.

J. Yang, K. Hanada, Qiong J. Wang, 2011, Blood.

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.

S. Rosenberg, J. Rossi, J. Yang, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity

Matthew Grist, P. Jänne, K. Varnäs, 2016, Clinical Cancer Research.

Metastasectomy Following Immunotherapy with Adoptive Cell Transfer for Patients with Advanced Melanoma

S. Rosenberg, J. Yang, D. Schrump, 2016, Annals of Surgical Oncology.

1235TiP Perioperative pembrolizumab + platinum-based chemotherapy for resectable locally advanced non-small cell lung cancer: The phase III KEYNOTE-671 study

M. Tsuboi, H. Wakelee, J. Yang, 2020 .

Osimertinib in patients with T790M mutation‐positive, advanced non–small cell lung cancer: Long‐term follow‐up from a pooled analysis of 2 phase 2 studies

P. Jänne, L. Sequist, T. Mitsudomi, 2018, Cancer.

Treatment of Metastatic Melanoma Using Interleukin-2 Alone or in Conjunction with Vaccines

S. Steinberg, S. Rosenberg, J. Yang, 2008, Clinical Cancer Research.

Liver Resection for Metastatic Melanoma with Postoperative Tumor-Infiltrating Lymphocyte Therapy

S. Steinberg, S. Libutti, S. Rosenberg, 2009, Annals of Surgical Oncology.

Esomeprazole-induced Stevens-Johnson syndrome in a patient who underwent nivolumab therapy for advanced lung adenocarcinoma.

J. Yang, C. Chu, Yi-Tsz Lin, 2020, Lung cancer.

Acute and long term effects on limb function of combined modality therapy in patients treated with limb sparing surgery for soft tissue sarcoma of the extremity

D. Venzon, S. Rosenberg, T. Delaney, 1990 .

Routine Computer Tomography Imaging for the Detection of Recurrences in High-Risk Melanoma Patients

S. Rosenberg, J. Yang, D. White, 2017, Annals of Surgical Oncology.

SEVEN Adoptive T-Cell Therapy for Cancer

S. Rosenberg, J. Yang, 2016 .

Localization of 111Indium‐labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response

S. Steinberg, S. Rosenberg, B. Pockaj, 1994, Cancer.

Novel biochemistry: post-translational protein splicing and other lessons from the school of antigen processing

J. Yang, K. Hanada, 2005, Journal of Molecular Medicine.

Reply to "Cancer vaccines: pessimism in check"

S. Rosenberg, J. Yang, N. Restifo, 2004, Nature Medicine.

Cell Transfer Therapy for Cancer: Lessons from Sequential Treatments of a Patient With Metastatic Melanoma

Steven A. Rosenberg, Douglas J. Schwartzentruber, S. Rosenberg, 2003, Journal of immunotherapy.

A phase I/II clinical trial of E6 T-cell receptor gene therapy for human papillomavirus (HPV)-associated epithelial cancers.

S. Rosenberg, J. Yang, W. Faquin, 2017 .

Treatment of oligometastases after successful immunotherapy.

J. Yang, R. Sherry, J. Abad, 2006, Seminars in radiation oncology.

Tumor-specific CD4+ Melanoma Tumor-infiltrating Lymphocytes

S. Rosenberg, J. Yang, M. Dudley, 2012, Journal of immunotherapy.

The Envelope Protein of an Endogenous Murine Retrovirus Is a Tumor-Associated T-Cell Antigen for Multiple Murine Tumors

J. Yang, D. Perry-Lalley, 2000, Journal of immunotherapy.

Altered CD8+ T-Cell Responses When Immunizing With Multiepitope Peptide Vaccines

S. Rosenberg, J. Yang, S. Topalian, 2006, Journal of immunotherapy.

CD70, a novel target of CAR T-cell therapy for gliomas

J. Yang, Y. Shang, D. Lu, 2018, Neuro-oncology.

Generating Renal Cancer-Reactive T Cells Using Dendritic Cells (DCs) to Present Autologous Tumor

J. Yang, T. Karpova, M. Bettinotti, 2005, Journal of immunotherapy.

Expression profiling of TCR-engineered T cells demonstrates overexpression of multiple inhibitory receptors in persisting lymphocytes.

S. Rosenberg, R. Morgan, J. Yang, 2013, Blood.

Osimertinib activity in patients (pts) with leptomeningeal (LM) disease from non-small cell lung cancer (NSCLC): Updated results from BLOOM, a phase I study.

M. Ahn, Haiyi Jiang, Dong-Wan Kim, 2016 .

Clinical Cancer esearch cer Therapy : Clinical cessful Treatment of Melanoma Brain R astases with Adoptive Cell Therapy

S. Rosenberg, J. Butman, J. Yang, 2010 .

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S. Rosenberg, J. Butman, J. Yang, 2010 .

Tumor Immunology and Immunotherapy

J. Tomlinson, J. Yang, J. Economou, 2012 .

Treatment of Patients with T Cells Expressing a Fully-Human Anti-BCMA CAR with a Heavy-Chain Antigen-Recognition Domain Caused High Rates of Sustained Complete Responses and Relatively Mild Toxicity

S. Rosenberg, T. Lowe, J. Yang, 2021, Blood.

Deep and Durable Remissions of Relapsed Multiple Myeloma on a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain

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Phase III, Randomized, Placebo-Controlled, Double-Blind Trial of Motesanib (AMG-706) in Combination With Paclitaxel and Carboplatin in East Asian Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.

Keunchil Park, Y. Ichinose, E. Cho, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Weaning outcome of solid cancer patients requiring mechanical ventilation in the intensive care unit.

K. Cheng, J. Yang, Chong-Jen Yu, 2019, Journal of the Formosan Medical Association = Taiwan yi zhi.

Treating patients with ALK-positive non-small cell lung cancer: latest evidence and management strategy

J. Shih, J. Yang, Chia‐Chi Lin, 2015, Therapeutic advances in medical oncology.

Pooled overall survival and safety data from the pivotal phase II studies (NP28673 and NP28761) of alectinib in ALK-positive non-small-cell lung cancer.

R. Govindan, S. Ou, A. Shaw, 2019, Lung cancer.

Enhancing Anticancer Effect of Gefitinib across the Blood–Brain Barrier Model Using Liposomes Modified with One α-Helical Cell-Penetrating Peptide or Glutathione and Tween 80

J. Yang, Y. Lo, A. Lin, 2016, International journal of molecular sciences.

Efficacy and Safety of S-1 Compared With Docetaxel in Elderly Patients With Advanced NSCLC Previously Treated With Platinum-Based Chemotherapy: A Subgroup Analysis of the EAST-LC Trial

T. Mok, J. Yang, S. Morita, 2021, JTO clinical and research reports.

Neoadjuvant chemotherapy with docetaxel-cisplatin in patients with stage III N2 non-small-cell lung cancer.

J. Shih, J. Yang, Chong-Jen Yu, 2013, Clinical lung cancer.

Advanced non-small cell lung cancer in the elderly: the impact of age and comorbidities on treatment modalities and patient prognosis.

J. Shih, Pan‐Chyr Yang, J. Yang, 2015, Journal of geriatric oncology.

Osimertinib in Patients with T790M-Positive Advanced Non-small Cell Lung Cancer: Korean Subgroup Analysis from Phase II Studies

T. Mitsudomi, M. Ahn, Dong-Wan Kim, 2019, Cancer research and treatment : official journal of Korean Cancer Association.

Phase II study of crizotinib in east Asian patients (pts) with ROS1-positive advanced non-small cell lung cancer (NSCLC).

T. Yamanaka, M. Ahn, Yi-long Wu, 2016 .

Updated results of a phase 1 study of EGF816, a third-generation, mutant-selective EGFR tyrosine kinase inhibitor (TKI), in advanced non-small cell lung cancer (NSCLC) harboring T790M.

L. Sequist, Gregory Riely, E. Felip, 2016 .

Interim safety and clinical activity in patients with advanced NSCLC from a multi-cohort phase 1 study of ramucirumab (R) plus pembrolizumab (P)

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Precision Management of Advanced Non-Small Cell Lung Cancer.

Pan‐Chyr Yang, J. Yang, Ching-Yao Yang, 2020, Annual review of medicine.

Multi-gene analyses from waste brushing specimens for patients with peripheral lung cancer receiving EBUS-assisted bronchoscopy.

J. Shih, Pan‐Chyr Yang, J. Yang, 2013, Lung cancer.

Phase I study of AZD3759, a CNS penetrable EGFR inhibitor, for the treatment of non-small-cell lung cancer (NSCLC) with brain metastasis (BM) and leptomeningeal metastasis (LM).

M. Ahn, Haiyi Jiang, Dong-Wan Kim, 2016 .

Anaplastic Lymphoma Kinase (ALK) Kinase Domain Mutation Following ALK Inhibitor(s) Failure in Advanced ALK Positive Non-Small-Cell Lung Cancer: Analysis and Literature Review.

Chong-Jen Yu, Jin-Yuan Shih, J. Shih, 2016, Clinical lung cancer.

First-in-human phase I study of EGF816, a third generation, mutant-selective EGFR tyrosine kinase inhibitor, in advanced non-small cell lung cancer (NSCLC) harboring T790M.

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Pembrolizumab (pembro) plus chemotherapy as front-line therapy for advanced NSCLC: KEYNOTE-021 cohorts A-C.

L. Sequist, H. Borghaei, A. Patnaik, 2016 .

Circulating Exosomal Integrin β3 Is Associated with Intracranial Failure and Survival in Lung Cancer Patients Receiving Cranial Irradiation for Brain Metastases: A Prospective Observational Study

J. Yang, J. Cheng, F. Hsu, 2021, Cancers.

First-Line Pemetrexed Plus Cisplatin Followed by Gefitinib Maintenance Therapy Versus Gefitinib Monotherapy in East Asian Never-Smoker Patients With Locally Advanced or Metastatic Nonsquamous Non-Small-cell Lung Cancer: Quality of Life Results From a Randomized Phase III Trial.

Chun-Ming Tsai, J. Yang, Jin-Hyoung Kang, 2016, Clinical lung cancer.

Bevacizumab for Patients with Metastatic Renal Cancer

J. Yang, 2004, Clinical Cancer Research.

Abstract 127: Single cell mapping of tumor infiltrating lymphocytes enables neoantigen-reactive T cell identification in metastatic human cancer

S. Rosenberg, J. Yang, Frank J. Lowery, 2021, Tumor Biology.

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer

J. Shih, Hsuan-Yu Chen, Sung-Liang Yu, 2015, Oncotarget.

Sequential afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: final analysis of the GioTag study.

B. Halmos, J. Yang, T. Čufer, 2020, Future oncology.

Antitumor activity of sunvozertinib in NSCLC patients with EGFR Exon20 insertion mutations after platinum and anti-PD(L)1 treatment failures.

Ying Cheng, C. Chiu, P. Janne, 2022, Journal of Clinical Oncology.

Phase (Ph) 1/2a study of CLN-081 in patients (pts) with NSCLC with EGFR exon 20 insertion mutations (Ins20).

M. Socinski, E. Smit, V. Lee, 2022, Journal of Clinical Oncology.

Sunvozertinib, a Selective EGFR Inhibitor for Previously Treated Non–Small Cell Lung Cancer with EGFR Exon 20 Insertion Mutations

Ying Cheng, C. Chiu, P. Janne, 2022, Cancer discovery.

Mobocertinib (TAK-788) in EGFR exon 20 insertion (ex20ins)+ metastatic NSCLC (mNSCLC): Additional results from platinum-pretreated patients (pts) and EXCLAIM cohort of phase 1/2 study.

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Afatinib for the treatment of non-small cell lung cancer harboring uncommon EGFR mutations: a database of 693 cases

J. Yang, 2021 .

Osimertinib plus selumetinib in EGFR-mutated, non-small cell lung cancer after progression on EGFR-TKIs: A Phase 1b, open-label, multicenter trial (TATTON Part B).

P. Jänne, M. Ahn, Y. Ohe, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

Efficacy of Aumolertinib (HS-10296) in Patients with Advanced EGFR T790M+ NSCLC: Updated Post NMPA-approval Results from the APOLLO Registrational Trial.

Ping Wang, Ying Cheng, C. Chiu, 2021, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Nivolumab + chemotherapy vs chemotherapy in EGFR-mutated NSCLC after 1L or 2L EGFR-TKIs (CheckMate 722)

N. Girard, Keunchil Park, T. Mok, 2019, Annals of Oncology.

Association of Programmed Death-Ligand 1 Expression with Fusion Variants and Clinical Outcomes in Patients with Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinoma Receiving Crizotinib.

Yih-Leong Chang, J. Shih, Chen‐Tu Wu, 2020, The oncologist.

Sequential afatinib and osimertinib in patients with EGFR mutation-positive non-small-cell lung cancer: updated analysis of the observational GioTag study.

B. Halmos, J. Yang, T. Čufer, 2019, Future oncology.

First-line afatinib (A) vs gefitinib (G) for patients (pts) with EGFR mutation positive (EGFRm+) NSCLC (LUX-Lung 7): Patient-reported outcomes (PROs) and impact of dose modifications on efficacy and adverse events (AEs).

K. O'Byrne, Keunchil Park, T. Mok, 2016 .

P3.02b-044 Afatinib versus Gefitinib as First-Line Treatment for EGFR Mutation-Positive NSCLC Patients Aged ≥75 Years: Subgroup Analysis of LUX-Lung 7: Topic: EGFR Clinical

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Brigatinib vs Alectinib in Crizotinib-Resistant Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer (ALTA-3).

Geoffrey Liu, J. Yang, S. Popat, 2021, Future oncology.

A Pilot Study of Antiangiogenic Therapy with Bevacizumab and Thalidomide in Patients with Metastatic Renal Cell Carcinoma

S. Steinberg, S. Rosenberg, J. Yang, 2004, Journal of immunotherapy.

Selection of circulating PD-1+ lymphocytes from cancer patients enriches for tumor-reactive and mutation-specific lymphocytes

J. Gartner, S. Rosenberg, S. Ilyas, 2015, Journal of Immunotherapy for Cancer.

Biomarker Analyses from a Randomized, Placebo-Controlled, Phase IIIb Trial Comparing Bevacizumab with or without Erlotinib as Maintenance Therapy for the Treatment of Advanced Non-Small-Cell Lung Cancer (ATLAS)

J. Hainsworth, V. Miller, F. Kabbinavar, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

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Afatinib monotherapy in patients with metastatic squamous cell carcinoma of the lung progressing after erlotinib/gefitinib (E/G) and chemotherapy: Interim subset analysis from a phase III trial.

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Interim analysis of afatinib monotherapy in patients with metastatic NSCLC progressing after chemotherapy and erlotinib/gefitinib (E/G) in a trial of afatinib plus paclitaxel versus investigator’s choice chemotherapy following progression on afatinib monotherapy.

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Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus

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Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2.

S. Rosenberg, J. Yang, S. Topalian, 1994, Journal of the National Cancer Institute.

Radiofrequency Ablation Is Superior to Ethanol Injection in Early-Stage Hepatocellular Carcinoma Irrespective of Tumor Size

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Correlation between overall response rate and progression-free survival/overall survival in comparative trials involving targeted therapies in molecularly enriched populations.

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Combination therapy with interleukin-2 and alpha-interferon for the treatment of patients with advanced cancer.

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A Phase 1b Study of Osimertinib Plus Savolitinib in Patients with EGFR Mutation-Positive, MET-Amplified, Non-Small Cell Lung Cancer after Progression on EGFR-Tyrosine Kinase Inhibitors

L. Sequist, M. Ahn, J. Yang, 2019, SSRN Electronic Journal.

Phase I S tudy o f t he I ntravenous A dministration o f Attenuated Salmonella t yphimurium to P atients W ith Metastatic M elanoma

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Abstract 3725: Combined cytotoxic effects of volasertib and cisplatin in urothelial carcinoma cells

Chia-Chi Lin, Yu-Chieh Tsai, J. Yang, 2012 .

Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours

N. Strelkowa, J. Yang, Chih-Hung Hsu, 2020, British Journal of Cancer.

Phase I study (BLOOM) of AZD3759, a BBB penetrable EGFR inhibitor, in EGFRm NSCLC patients with leptomeningeal metastasis (LM) who progressed after other anti-cancer therapy.

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A selective ALK inhibitor in ALK-rearranged patients.

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Rapid Response to Sunitinib in a Patient with Lung Adenocarcinoma Harboring KIF5B-RET Fusion Gene.

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A Phase I study of an HLA-DPB1*0401-restricted T cell receptor targeting MAGE-A3 for patients with metastatic cancers

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AZD9291, a mutant-selective EGFR inhibitor, as first-line treatment for EGFR mutation-positive advanced non-small cell lung cancer (NSCLC): Results from a phase 1 expansion cohort.

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Linking laboratory and clinical research: the development of molecularly targeted therapeutics inside the national cancer institute center for cancer research.

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Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2.

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Durability of complete responses in patients with metastatic cancer treated with high-dose interleukin-2: identification of the antigens mediating response.

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Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas.

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First-line carboplatin and pemetrexed (CP) with or without pembrolizumab (pembro) for advanced nonsquamous NSCLC: Updated results of KEYNOTE-021 cohort G.

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Preliminary Phase II results of a multicenter, open-label study of nazartinib (EGF816) in adult patients with treatment-naïve EGFR-mutant non-small cell lung cancer (NSCLC).

L. Sequist, E. Smit, E. Felip, 2018 .

Cytotoxic T-lymphocyte-associated antigen-4 blockage can induce autoimmune hypophysitis in patients with metastatic melanoma and renal cancer.

S. Rosenberg, J. Yang, S. Topalian, 2005, Journal of immunotherapy.

An ongoing prospective randomized comparison of interleukin-2 regimens for the treatment of metastatic renal cell cancer.

S. Rosenberg, J. Yang, J. Yang, 1997, The cancer journal from Scientific American.

Next-Generation Approaches to Immuno-Oncology in GI Cancers.

J. Hecht, J. Yang, M. Morelli, 2023, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

Phase I study (BLOOM) of AZD3759, a BBB penetrable EGFR inhibitor, in patients with TKI-naïve, EGFRm NSCLC with CNS metastases.

J. Ahn, M. Ahn, Dong-Wan Kim, 2017 .

Genomic profiling of resistant tumor samples following progression on EGF816, a third generation, mutant-selective EGFR tyrosine kinase inhibitor (TKI), in advanced non-small cell lung cancer (NSCLC).

J. Barretina, L. Sequist, Gregory Riely, 2017 .

49 – Management of Toxicities of Targeted Therapies

J. Yang, Chia‐Chi Lin, C. Chu, 2018 .

Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in ALK-positive NSCLC

A. Dingemans, A. Shaw, S. Ou, 2017, British Journal of Cancer.

Pooled mutation analysis for the NP28673 and NP28761 studies of alectinib in ALK+ non-small-cell lung cancer (NSCLC).

Aaron M. Newman, A. Shaw, S. Ou, 2016 .

The Prognostic Impact of Type 2 Diabetes Mellitus on Early Cervical Cancer in Asia.

M. Lai, Chiun Hsu, J. Yang, 2015, The oncologist.

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy.

S. Rosenberg, J. Rossi, J. Yang, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells.

S. Rosenberg, R. Morgan, J. Yang, 2012, Blood.

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.

D. Douek, S. Rosenberg, S. Darko, 2014, The Journal of clinical investigation.

The use of interleukin-2 and lymphokine-activated killer cells for the treatment of patients with non-Hodgkin's lymphoma.

S. Rosenberg, J. Yang, S. Topalian, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer.

P. Jänne, M. Ranson, M. Ahn, 2015, The New England journal of medicine.

Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.

V. Gebski, S. Thongprasert, D. Chu, 2013, Journal of the National Cancer Institute.

Interview: Changing advanced lung cancer into chronic disease

J. Yang, 2014 .

Sequencing of therapy following first-line afatinib in patients with EGFR mutation-positive non-small cell lung cancer.

K. O'Byrne, Keunchil Park, T. Mok, 2019, Lung cancer.

Abstract CT033: TATTON Phase Ib expansion cohort: Osimertinib plus savolitinib for patients (pts) withEGFR-mutant,MET-amplified NSCLC after progression on prior third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)

L. Sequist, J. Yang, B. Cho, 2019, Clinical Trials.

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the ‘real-world’ clinical setting

Keunchil Park, J. Yang, I. Okamoto, 2019, Therapeutic advances in medical oncology.

Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.

L. Sequist, H. Borghaei, S. Jalal, 2016, The Lancet. Oncology.

L. Sequist, J. Yang, 2014 .

Bevacizumab reduces the growth rate constants of renal carcinomas: a novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage.

T. Fojo, S. Bates, J. Yang, 2008, The oncologist.

Keunchil Park, Y. Ichinose, E. Cho, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Combination chemoimmunotherapy for metastatic colorectal cancer using 5-fluorouracil, leucovorin and interleukin-2.

E. Shlasko, S. Rosenberg, J. Yang, 1993, European journal of cancer.

Randomized, Prospective Evaluation Comparing Intensity of Lymphodepletion Before Adoptive Transfer of Tumor-Infiltrating Lymphocytes for Patients With Metastatic Melanoma.

S. Steinberg, S. Rosenberg, D. Citrin, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Neoadjuvant chemotherapy with docetaxel-cisplatin in patients with stage III N2 non-small-cell lung cancer.

J. Shih, J. Yang, Chong-Jen Yu, 2013, Clinical lung cancer.

Polo-like Kinase 1 Inhibitors and Their Potential Role in Anticancer Therapy, with a Focus on Nsclc Current Treatment Options Novel Approaches Targeting Mitosis

J. Yang, Chia‐Chi Lin, Ren, 2022 .

Alveolar soft part sarcoma: the role of prognostic markers.

M. Merino, J. Yang, M. Sobel, 2000, Annals of diagnostic pathology.

IL-17 Secreted by Tumor Reactive T Cells Induces IL-8 Release by Human Renal Cancer Cells

J. Yang, K. Hanada, Qiong J. Wang, 2009, Journal of immunotherapy.

Vitespen: a vaccine for renal cancer?

J. Yang, 2008, The Lancet.

213 A phase I dose-finding study of BI 853520, a potent and selective inhibitor of focal adhesion kinase (FAK), in Japanese and Taiwanese patients with advanced or metastatic solid tumors

J. Yang, A. Ohtsu, A. Cheng, 2014 .