J. Duarte

发表

Endothelial function and cardiovascular disease: Effects of quercetin and wine polyphenols

F. Perez-Vizcaino, J. Duarte, R. Andriantsitohaina, 2006, Free radical research.

Flecainide increases Kir2.1 currents by interacting with cysteine 311, decreasing the polyamine-induced rectification

J. Tamargo, J. Duarte, Ignacio Moraleda, 2010, Proceedings of the National Academy of Sciences.

Role of UCP2 in the protective effects of PPARβ/δ activation on lipopolysaccharide-induced endothelial dysfunction.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2016, Biochemical pharmacology.

Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2011, Clinical science.

Involvement of protein kinase C in reduced relaxant responses to the NO/cyclic GMP pathway in piglet pulmonary arteries contracted by the thromboxane A2‐mimetic U46619

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1997, British journal of pharmacology.

Identification and characterization of novel angiotensin-converting enzyme inhibitors obtained from goat milk.

Manuel Calderón Sánchez, J. Duarte, J. Boza, 2006, Journal of dairy science.

Antihypertensive e ects of the ̄ avonoid quercetin in spontaneously hypertensive rats

J. Tamargo, J. Duarte, A. Zarzuelo, 2001 .

Glucuronidated Quercetin Lowers Blood Pressure in Spontaneously Hypertensive Rats via Deconjugation

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2012, PloS one.

Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats.

J. Duarte, Á. Cogolludo, M. Toral, 2015, Food & function.

Different cardiovascular protective effects of quercetin administered orally or intraperitoneally in spontaneously hypertensive rats.

J. Duarte, C. Santos-Buelga, A. González-Paramás, 2012, Food & function.

Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed?

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2011, Molecular nutrition & food research.

Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta.

J. Tamargo, L. Moreno, F. Perez-Vizcaino, 2007, The Journal of nutrition.

The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells.

J. Mitchell, L. Moreno, F. Perez-Vizcaino, 2006, Biochemical and biophysical research communications.

Involvement of thromboxane A2 in the endothelium‐dependent contractions induced by myricetin in rat isolated aorta

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1999, British journal of pharmacology.

Epicatechin lowers blood pressure, restores endothelial function, and decreases oxidative stress and endothelin-1 and NADPH oxidase activity in DOCA-salt hypertension.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2012, Free radical biology & medicine.

Chronic ( − )-epicatechin improves vascular oxidative and inflammatory status but not hypertension in chronic nitric oxide-deficient rats

F. Perez-Vizcaino, J. Duarte, F. O'Valle, 2011, British Journal of Nutrition.

Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2010, European journal of pharmacology.

Lack of bene fi cial metabolic effects of quercetin in adult spontaneously hypertensive rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2010 .

Genistein restores caveolin-1 and AT-1 receptor expression and vascular function in large vessels of ovariectomized hypertensive rats

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2007, Menopause.

Effects of factor Xa on the expression of proteins in femoral arteries from type 2 diabetic patients.

J. Duarte, G. Moñux, J. Serrano, 2014, British journal of clinical pharmacology.

Increased Klk9 Urinary Excretion Is Associated to Hypertension-Induced Cardiovascular Damage and Renal Alterations

J. Duarte, J. López-Novoa, C. Martínez-Salgado, 2015, Medicine.

Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity.

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2007, Clinical science.

The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids.

F. Perez-Vizcaino, J. Duarte, C. Santos-Buelga, 2012, Journal of the science of food and agriculture.

Chronic Hydroxychloroquine Improves Endothelial Dysfunction and Protects Kidney in a Mouse Model of Systemic Lupus Erythematosus

F. Perez-Vizcaino, J. Duarte, F. O'Valle, 2014, Hypertension.

Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats

J. Duarte, A. Zarzuelo, M. Galisteo, 2004, Molecular and Cellular Biochemistry.

Effects of chronic quercetin treatment on hepatic oxidative status of spontaneously hypertensive rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2001, Molecular and Cellular Biochemistry.

Protective vascular effects of quercitrin in acute TNBS-colitis in rats: the role of nitric oxide.

F. Perez-Vizcaino, J. Duarte, J. Gálvez, 2017, Food & function.

Cardiovascular effects of captopril and enalapril in obese Zucker rats.

J. Duarte, A. Bermejo, A. Zarzuelo, 1999, European journal of pharmacology.

The prebiotic properties of Hibiscus sabdariffa extract contribute to the beneficial effects in diet-induced obesity in mice.

D. Arráez-Román, A. Segura‐Carretero, J. Duarte, 2020, Food research international.

SOY ISOFLAVONES IMPROVE ENDOTHELIAL FUNCTION IN SHR RATS IN AN ESTROGEN-INDEPENDENT MANNER: ROLE OF NO SYNTHASE, SUPEROXIDE AND CYCLOOXYGENASE METABOLITES

Manuel Calderón Sánchez, F. Perez-Vizcaino, J. Duarte, 2005 .

Soy Isoflavones Improve Endothelial Function in Spontaneously Hypertensive Rats in an Estrogen-Independent Manner: Role of Nitric-Oxide Synthase, Superoxide, and Cyclooxygenase Metabolites

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2005, Journal of Pharmacology and Experimental Therapeutics.

The Beneficial Effects of Lippia Citriodora Extract on Diet-Induced Obesity in Mice are Associated with the Modulation in the Gut Microbiota Composition.

J. Lozano-Sánchez, D. Arráez-Román, A. Segura‐Carretero, 2020, Molecular nutrition & food research.

Endothelium-Dependent Vasodilator Effects of Peroxisome Proliferator-Activated Receptor β Agonists via the Phosphatidyl-Inositol-3 Kinase-Akt Pathway

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2010, Journal of Pharmacology and Experimental Therapeutics.

Role of sex, gonadectomy and sex hormones in the development of nitric oxide inhibition‐induced hypertension

J. Duarte, J. Sainz, J. D. Luna, 2004, Experimental physiology.

The Antioxidant Activity of Thymus serpyllum Extract Protects against the Inflammatory State and Modulates Gut Dysbiosis in Diet-Induced Obesity in Mice

J. Duarte, J. Gálvez, I. Pischel, 2022, Antioxidants.

Critical Role of the Interaction Gut Microbiota – Sympathetic Nervous System in the Regulation of Blood Pressure

J. Duarte, M. Raizada, Tao Yang, 2019, Front. Physiol..

Vascular reactivity in chronic Goldblatt two kidney-one clip hypertensive rats

J. Duarte, F. Vargas, J. Andrade, 1990, Experientia.

Chronic peroxisome proliferator-activated receptor&bgr;/&dgr; agonist GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity

C. Hermenegildo, F. Perez-Vizcaino, J. Duarte, 2015, Journal of hypertension.

Effects of flavonoids on rat aortic smooth muscle contractility: structure-activity relationships.

J. Duarte, A. Zarzuelo, M. Herrera, 1996, General pharmacology.

The Role of Nrf2 Signaling in PPARβ/δ-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress

J. Duarte, A. Mahmoud, M. Toral, 2018, Oxidative medicine and cellular longevity.

The Role of Nrf 2 Signaling in PPAR β / δ-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress

J. Duarte, A. Mahmoud, M. Toral, 2018 .

Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2013, Cardiovascular research.

Thyroid hormones stimulate L-arginine transport in human endothelial cells.

J. Duarte, Sebastián Montoro-Molina, F. Vargas, 2018, The Journal of endocrinology.

Role of the immune system in vascular function and blood pressure control induced by faecal microbiota transplantation in rats

J. Duarte, M. Raizada, Tao Yang, 2019, Acta physiologica.

Lactobacillus fermentum Improves Tacrolimus‐Induced Hypertension by Restoring Vascular Redox State and Improving eNOS Coupling

F. Perez-Vizcaino, J. Duarte, M. Olivares, 2018, Molecular nutrition & food research.

Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2012, Free radical biology & medicine.

Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus

J. Duarte, M. Toral, I. Robles‐Vera, 2019, Nutrients.

Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats.

J. Duarte, M. Olivares, J. Gálvez, 2016, Food & function.

Vitamin D deficiency downregulates TASK-1 channels and induces pulmonary vascular dysfunction.

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2020, American journal of physiology. Lung cellular and molecular physiology.

Role of endothelium-derived relaxing factors in adrenomedullin-induced vasodilation in the rat kidney.

J. Duarte, J. Sainz, A. Quesada, 2002, European journal of pharmacology.

Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats

Manuel Calderón Sánchez, J. Duarte, F. Vargas, 2021, Nutrients.

The melatonergic agonist agomelatine ameliorates high fat diet-induced obesity in mice through the modulation of the gut microbiome.

Manuel Calderón Sánchez, J. Duarte, J. Gálvez, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Lactobacillus fermentum CECT5716 ameliorates high fat diet-induced obesity in mice through modulation of gut microbiota dysbiosis.

J. Duarte, M. Olivares, J. Plaza-Díaz, 2020, Pharmacological research.

REVIEW Small Vessels-Big Problems: Novel Insights into Microvascular Mechanisms of Diseases Antihypertensive effects of peroxisome proliferator-activated receptor- (cid:2) / (cid:3) activation

F. Perez-Vizcaino, J. Duarte, M. Toral, 2017 .

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome

H. Prokisch, M. Schuelke, J. Duarte, 2016, EMBO molecular medicine.

Vascular superoxide production by endothelin-1 requires Src non-receptor protein tyrosine kinase and MAPK activation.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2010, Atherosclerosis.

Effects of flecainide on isolated vascular smooth muscles of rat

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1991, British journal of pharmacology.

Toll-like receptor 7-driven lupus autoimmunity induces hypertension and vascular alterations in mice.

J. Duarte, F. O'Valle, M. Toral, 2020, Journal of hypertension.

Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress

J. Duarte, F. Wilkinson, M. Alexander, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effect of tyrosine kinase and tyrosine phosphatase inhibitors on aortic contraction and induction of nitric oxide synthase.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1997, European journal of pharmacology.

Antihypertensive effects of probiotics Lactobacillus strains in spontaneously hypertensive rats.

J. Duarte, M. Olivares, J. Gálvez, 2015, Molecular nutrition & food research.

β‐RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice

J. Duarte, C. Prehn, D. Acuña-Castroviejo, 2018, EMBO molecular medicine.

Effects of aminophylline on contractions and 45Ca uptake in isolated rat vascular smooth muscle.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1992, General pharmacology.

Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1993, European journal of pharmacology.

New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres.

J. Duarte, I. López-Vílchez, G. Escolar, 2016, Transplant immunology.

Carnitine palmitoyltransferase-1 up-regulation by PPAR-β/δ prevents lipid-induced endothelial dysfunction.

F. Perez-Vizcaino, J. Duarte, A. Briones, 2015, Clinical science.

Antihypertensive Effects of Virgin Olive Oil (Unfiltered) Low Molecular Weight Peptides with ACE Inhibitory Activity in Spontaneously Hypertensive Rats

J. Duarte, E. López-Huertas, J. M. Alcaide-Hidalgo, 2020, Nutrients.

Trimethylamine N-Oxide Promotes Autoimmunity and a Loss of Vascular Function in Toll-like Receptor 7-Driven Lupus Mice

J. Duarte, M. Romero, R. Jiménez, 2021, Antioxidants.

imbalance and depresses NOS protein expression endothelial dysfunction and oxidant/antioxidant A high-fat, refined-carbohydrate diet induces

J. Duarte, X. Kong, N. Vaziri, 2015 .

Activation of peroxisome proliferator-activated receptor-b /-d ( PPAR b / d ) prevents endothelial dysfunction in type 1 diabetic rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2012 .

Vasoconstrictor and Pressor Effects of Des-Aspartate-Angiotensin I in Rat

J. Duarte, J. García-Estañ, F. Vargas, 2022, Biomedicines.

Vasodilator Effect of Olive Leaf

A. Zarzuelo, J. Duarte, A. Zarzuelo, 1991, Planta medica.

Increased Pressor Sensitivity to Chronic Nitric Oxide Deficiency in Hyperthyroid Rats

J. Duarte, J. Sainz, A. Osuna, 2003, Hypertension.

Involvement of protein kinase C and Na+/K+-ATPase in the contractile response induced by myricetin in rat isolated aorta.

J. Duarte, A. Zarzuelo, M. Galisteo, 2002, Planta medica.

Bioactive imidamide-based compounds targeted against nitric oxide synthase.

J. Duarte, M. Romero, Fabio Arias, 2022, Bioorganic chemistry.

Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats.

J. Duarte, J. Sainz, A. Osuna, 2004, Clinical science.

Effects of oleuropeoside in isolated guinea-pig atria.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1993, Planta medica.

Impact of Nutrition on Pulmonary Arterial Hypertension

J. Barberà, F. Perez-Vizcaino, J. Duarte, 2020, Nutrients.

Thiadiazoline- and Pyrazoline-Based Carboxamides and Carbothioamides: Synthesis and Inhibition against Nitric Oxide Synthase

J. Duarte, M. Gallo, M. Romero, 2018 .

N , N ′-Disubstituted thiourea and urea derivatives: design, synthesis, docking studies and biological evaluation against nitric oxide synthase

J. Duarte, M. Gallo, M. Romero, 2016 .

Development of Urea and Thiourea Kynurenamine Derivatives: Synthesis, Molecular Modeling, and Biological Evaluation as Nitric Oxide Synthase Inhibitors

J. Duarte, M. Gallo, R. Jiménez, 2015, ChemMedChem.

Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2001, British journal of pharmacology.

In Vivo Vascular Effects of Genistein on a Rat Model of Septic Shock Induced by Lipopolysaccharide

J. Duarte, A. Bermejo, A. Zarzuelo, 2003, Journal of cardiovascular pharmacology.

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2002, Journal of hypertension.

Inhibitory effects of quercetin on guinea‐pig ileum contractions

J. Duarte, A. Zarzuelo, J. Gálvez, 1996 .

Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Attenuates Metabolic Alterations in Mice Fed a High-Fat Diet through Its Anti-Inflammatory and Prebiotic Properties

Manuel Calderón Sánchez, J. Duarte, J. Gálvez, 2021, Nutrients.

Vasodilator effects of quercetin in isolated rat vascular smooth muscle.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1993, European journal of pharmacology.

Cardiovascular effects of flavonoids.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2019, Current medicinal chemistry.

Epicatechin: endothelial function and blood pressure.

F. Perez-Vizcaino, J. Duarte, R. Jiménez, 2012, Journal of agricultural and food chemistry.

Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships.

J. Tamargo, J. Duarte, A. Zarzuelo, 1993, General pharmacology.

Flavonols and cardiovascular disease.

F. Perez-Vizcaino, J. Duarte, F. Pérez-Vizcaino, 2010, Molecular aspects of medicine.

Antihypertensive Effects of Probiotics

F. Perez-Vizcaino, J. Duarte, M. Toral, 2017, Current Hypertension Reports.

Effects of dietary fibers on disturbances clustered in the metabolic syndrome.

J. Duarte, A. Zarzuelo, M. Galisteo, 2008, Journal of Nutritional Biochemistry.

A diet supplemented with husks of Plantago ovata reduces the development of endothelial dysfunction, hypertension, and obesity by affecting adiponectin and TNF-alpha in obese Zucker rats.

J. Duarte, A. Zarzuelo, Anna Anguera, 2005, The Journal of nutrition.

Gut DYSBIOSIS and altered barrier function precedes the appearance of metabolic syndrome in a rat model of nutrient-induced catch-up growth.

J. Duarte, E. Fernández-Millán, C. Álvarez, 2020, The Journal of nutritional biochemistry.

Influence of thyroid state on cardiac and renal capillary density and glomerular morphology in rats.

Félix Vargas, Francisco O'Valle, Inmaculada Banegas, 2013, The Journal of endocrinology.

Gut microbiota contributes to the development of hypertension in a genetic mouse model of systemic lupus erythematosus

J. Duarte, Natividad Martín-Morales, M. Toral, 2021, British journal of pharmacology.

Probiotic Bifidobacterium breve prevents DOCA‐salt hypertension

F. Perez-Vizcaino, J. Duarte, J. L. Izquierdo-García, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Microbiota and hypertension: role of the sympathetic nervous system and the immune system.

J. Duarte, M. Toral, I. Robles‐Vera, 2020, American journal of hypertension.

Probiotics Prevent Dysbiosis and the Raise in Blood Pressure in Genetic Hypertension: Role of Short-chain Fatty Acids.

Manuel Calderón Sánchez, F. Perez-Vizcaino, J. Duarte, 2020, Molecular nutrition & food research.

Mycophenolate mediated remodeling of gut microbiota and improvement of gut-brain axis in spontaneously hypertensive rats.

Manuel Calderón Sánchez, J. Duarte, M. Toral, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Protective Effects of Short-Chain Fatty Acids on Endothelial Dysfunction Induced by Angiotensin II

J. Redondo, J. Duarte, M. Toral, 2020, Frontiers in Physiology.

Probiotics Prevent Hypertension in a Murine Model of Systemic Lupus Erythematosus Induced by Toll-Like Receptor 7 Activation

Manuel Calderón Sánchez, J. Duarte, M. Olivares, 2021, Nutrients.

The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity.

F. Perez-Vizcaino, J. Duarte, C. Santos-Buelga, 2014, Pharmacological research.

Role of endoplasmic reticulum stress in the protective effects of PPARβ/δ activation on endothelial dysfunction induced by plasma from patients with lupus

J. Duarte, J. Sabio, M. Salaices, 2017, Arthritis Research & Therapy.

Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1993, General pharmacology.

Effects of chronic chrysin treatment in spontaneously hypertensive rats.

J. Duarte, A. Zarzuelo, I. Villar, 2002, Planta medica.

Effects of Quercetin in a Rat Model of Hemorrhagic Traumatic Shock and Reperfusion

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2016, Molecules.

Activation of Peroxisome Proliferator Activator Receptor &bgr;/&dgr; Improves Endothelial Dysfunction and Protects Kidney in Murine Lupus

F. Perez-Vizcaino, J. Duarte, J. Gálvez, 2017, Hypertension.

Gender differences in the effects of cardiovascular drugs

D. Atar, B. Lewis, J. Tamargo, 2017, European heart journal. Cardiovascular pharmacotherapy.

The Flavonoid Quercetin Reverses Pulmonary Hypertension in Rats

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2014, PloS one.

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging.

F. Perez-Vizcaino, J. Duarte, M. Romero, 2013, Biochemical pharmacology.

Lactobacillus fermentum CECT5716: a novel alternative for the prevention of vascular disorders in a mouse model of systemic lupus erythematosus

J. Duarte, J. Gálvez, A. Rodríguez‐Nogales, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2001, Planta medica.

Antihypertensive effects of peroxisome proliferator-activated receptor-β/δ activation.

F. Perez-Vizcaino, J. Duarte, M. Toral, 2017, American journal of physiology. Heart and circulatory physiology.

Antihypertensive effects of the flavonoid quercetin

F. Perez-Vizcaino, J. Duarte, C. Santos-Buelga, 2009, Pharmacological reports : PR.

Changes to the gut microbiota induced by losartan contributes to its antihypertensive effects

J. Redondo, Manuel Calderón Sánchez, J. Duarte, 2020, British Journal of Pharmacology.

Changes to the gut microbiota induced by losartan contributes to its antihypertensive effects

J. Redondo, Manuel Calderón Sánchez, J. Duarte, 2019, British journal of pharmacology.

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2018, Scientific Reports.

Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats.

J. Tamargo, L. Moreno, F. Perez-Vizcaino, 2006, European journal of pharmacology.

New antihypertensive drugs under development.

L. Ruilope, J. Tamargo, J. Duarte, 2014, Current medicinal chemistry.

Effects of chronic quercetin treatment in experimental renovascular hypertension

J. Duarte, A. Bermejo, A. Zarzuelo, 2005, Molecular and Cellular Biochemistry.

The Probiotic Lactobacillus fermentum Prevents Dysbiosis and Vascular Oxidative Stress in Rats with Hypertension Induced by Chronic Nitric Oxide Blockade

J. Duarte, M. Olivares, M. Toral, 2018, Molecular nutrition & food research.

Wine Polyphenols Improve Endothelial Function in Large Vessels of Female Spontaneously Hypertensive Rats

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2008, Hypertension.

Data Supplement Wine Polyphenols Improve Endothelial Function In Large Vessels Of Female Spontaneously Hypertensive Rats

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2008 .

Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2006, Journal of hypertension.

A novel role for small molecule glycomimetics in the protection against lipid-induced endothelial dysfunction: Involvement of Akt/eNOS and Nrf2/ARE signaling.

J. Duarte, F. Wilkinson, M. Alexander, 2017, Biochimica et biophysica acta. General subjects.

Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats.

J. Tamargo, L. Moreno, F. Perez-Vizcaino, 2003, Planta medica.

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2009, Atherosclerosis.

Glucuronidated metabolites of the flavonoid quercetin do not auto-oxidise, do not generate free radicals and do not decrease nitric oxide bioavailability.

F. Perez-Vizcaino, J. Duarte, F. Lodi, 2008, Planta medica.

A new class of glycomimetic drugs to prevent free fatty acid-induced endothelial dysfunction

J. Duarte, F. Wilkinson, M. Alexander, 2016 .

Cardiovascular effects of visnagin on rats.

J. Duarte, A. Zarzuelo, A. I. Torres, 2000, Planta Medica.

Effects of visnagin on cyclic nucleotide phosphodiesterases and their role in its inhibitory effects on vascular smooth muscle contraction.

J. Tamargo, A. Zarzuelo, F. Perez-Vizcaino, 1999, General pharmacology.

Vasodilator effects of visnagin in isolated rat vascular smooth muscle.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1995, European journal of pharmacology.

Effects of the Dietary Flavonoid Chrysin in Isolated Rat Mesenteric Vascular Bed

J. Duarte, A. Zarzuelo, I. Villar, 2004, Journal of Vascular Research.

Lack of synergistic interaction between quercetin and catechin in systemic and pulmonary vascular smooth muscle.

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2011, The British journal of nutrition.

Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries.

J. Tamargo, L. Moreno, F. Perez-Vizcaino, 2002, The Journal of pharmacology and experimental therapeutics.

Impact of Vitamin D Deficit on the Rat Gut Microbiome

F. Perez-Vizcaino, J. Duarte, M. Callejo, 2019, Nutrients.

The metabolic and vascular protective effects of Olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties.

A. Gómez-Caravaca, D. Arráez-Román, A. Segura‐Carretero, 2019, Pharmacological research.

Mycophenolate Improves Brain–Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats

Manuel Calderón Sánchez, J. Duarte, M. Raizada, 2020, Antioxidants.

Vascular and Central Activation of Peroxisome Proliferator–Activated Receptor-β Attenuates Angiotensin II–Induced Hypertension: Role of RGS-5

J. Tamargo, C. Dessy, F. Perez-Vizcaino, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Antihypertensive Effects of Peroxisome Proliferator-Activated Receptor-&bgr; Activation in Spontaneously Hypertensive Rats

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2011, Hypertension.

PPARβ activation restores the high glucose‐induced impairment of insulin signalling in endothelial cells

J. Duarte, Á. Cogolludo, M. Toral, 2014, British journal of pharmacology.

Peroxisome proliferator-activated receptor-β activation restores the high glucose-induced impairment of insulin signaling in endothelial cells.

J. Duarte, Á. Cogolludo, M. Toral, 2014 .

The probiotic Lactobacillus coryniformis CECT5711 reduces the vascular pro-oxidant and pro-inflammatory status in obese mice.

J. Duarte, M. Olivares, N. Garrido-Mesa, 2014, Clinical science.

Inhibitory effects of quercetin and staurosporine on phasic contractions in rat vascular smooth muscle.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 1994, European journal of pharmacology.

Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase.

J. Duarte, C. Santos-Buelga, M. Dueñas, 2007, Free radical biology & medicine.

Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle.

J. Tamargo, L. Moreno, F. Perez-Vizcaino, 2004, Molecular pharmacology.

Lactobacillus fermentum CECT5716 prevents renal damage in the NZBWF1 mouse model of systemic lupus erythematosus.

Manuel Calderón Sánchez, J. Duarte, M. Toral, 2020, Food & function.

Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC.

F. Perez-Vizcaino, J. Duarte, A. Zarzuelo, 2009, Atherosclerosis.

Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria.

J. Tamargo, F. Perez-Vizcaino, J. Duarte, 2002, Planta medica.

Modulation of nitric oxide by flavonoids.

J. Duarte, V. Francisco, F. Pérez-Vizcaíno, 2014, Food & function.

Kv7 channels critically determine coronary artery reactivity: left-right differences and down-regulation by hyperglycaemia.

L. Moreno, F. Perez-Vizcaino, J. Duarte, 2015, Cardiovascular research.

The Prebiotic Effects of an Extract with Antioxidant Properties from Morus alba L. Contribute to Ameliorate High-Fat Diet-Induced Obesity in Mice

J. Duarte, J. Gálvez, A. Rodríguez‐Nogales, 2023, Antioxidants.

Gut Microbiota Has a Crucial Role in the Development of Hypertension and Vascular Dysfunction in Toll-like Receptor 7-Driven Lupus Autoimmunity

Manuel Calderón Sánchez, J. Duarte, Natividad Martín-Morales, 2021, Antioxidants.

Activation of PPARβ/δ prevents hyperglycaemia-induced impairment of Kv7 channels and cAMP-mediated relaxation in rat coronary arteries.

L. Moreno, J. Duarte, M. Callejo, 2016, Clinical science.

Mechanisms of hydrogen peroxide-induced vasoconstriction in the isolated perfused rat kidney.

J. Duarte, A. Osuna, F. Vargas, 2010, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil.

J. Duarte, A. Zarzuelo, I. Villar, 2004, Planta medica.

New therapeutic targets for the development of positive inotropic agents.

J. Tamargo, J. Duarte, R. Caballero, 2011, Discovery medicine.

Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta.

J. Duarte, A. Zarzuelo, I. Villar, 2005, Planta medica.

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

L. Moreno, J. Duarte, J. L. Izquierdo-García, 2018, Scientific Reports.

The hypoglycemic effects of guava leaf (Psidium guajava L.) extract are associated with improving endothelial dysfunction in mice with diet-induced obesity.

A. Segura‐Carretero, J. Duarte, J. Gálvez, 2017, Food research international.

Dietary vitamin E supplementation protects the rat large intestine from experimental inflammation.

J. Duarte, A. Zarzuelo, J. Gálvez, 2001, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.

Mineralocorticoid receptor blockade improved gut microbiota dysbiosis by reducing gut sympathetic tone in spontaneously hypertensive rats.

Manuel Calderón Sánchez, J. Duarte, Natividad Martín-Morales, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Cinaciguat, a soluble guanylate cyclase activator for the potential treatment of acute heart failure.

J. Tamargo, J. Duarte, R. Caballero, 2010, Current opinion in investigational drugs.

Probiotics and Prebiotics in Cardiovascular Diseases

J. Duarte, M. Romero, J. Duarte, 2023, Nutrients.