DelindaA . Johnson

发表

Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.

DelindaA . Johnson, Jeffrey A. Johnson, 2015, Free radical biology & medicine.

Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.

Jiang Li, Lynda Wright, Jiang Li, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Neurotoxicant-Induced Oxidative Events and Antioxidative Interventions in the Central Nervous System

DelindaA . Johnson, Jeffrey A. Johnson, Neal C. Burton, 2010 .

The Nrf2-ARE pathway: A potential therapeutic target for neurodegenerative diseases

DelindaA . Johnson, Jeffrey A. Johnson, M. Calkins, 2007 .

Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.

S. Werner, T. A. Beyer, DelindaA . Johnson, 2007, The Journal of investigative dermatology.

Nrf Transcription Factors in Keratinocytes Are Essential for Skin Tumor Prevention but Not for Wound Healing

P. Bugnon, S. Werner, T. A. Beyer, 2006, Molecular and Cellular Biology.

The effects of intermittent progesterone upon tamoxifen inhibition of tumor growth in the 7,12-dimethylbenzanthracene rat mammary tumor model

W. Wolberg, V. Jordan, DelindaA . Johnson, 2004, Breast Cancer Research and Treatment.

The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease.

Jiang Li, DelindaA . Johnson, Jeffrey A. Johnson, 2009, Antioxidants & redox signaling.

The Nrf2–ARE Pathway

DelindaA . Johnson, Jeffrey A. Johnson, M. Calkins, 2008, Annals of the New York Academy of Sciences.

Selenium deficiency activates mouse liver Nrf2-ARE but vitamin E deficiency does not.

DelindaA . Johnson, Jeffrey A. Johnson, Akihiro Nakayama, 2008, Free Radical Biology & Medicine.

Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental Validation

G. Joshi, DelindaA . Johnson, Jeffrey A. Johnson, 2012, Chemical biology & drug design.

Deletion of Nrf2 impairs functional recovery, reduces clearance of myelin debris and decreases axonal remyelination after peripheral nerve injury

DelindaA . Johnson, Jeffrey A. Johnson, Linxia Zhang, 2013, Neurobiology of Disease.

Keap1‐Nrf2 activation in the presence and absence of DJ‐1

L. Gan, DelindaA . Johnson, Jeffrey A. Johnson, 2010, The European journal of neuroscience.

Nrf2ActivationinAstrocytesProtectsagainst NeurodegenerationinMouseModelsofFamilial AmyotrophicLateralSclerosis

DelindaA . Johnson, Daniel W. Sirkis, Marcelo R Vargas, 2008 .

Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1G93A mice model

DelindaA . Johnson, Jeffrey A. Johnson, Marcelo R Vargas, 2011, Neurobiology of Disease.

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes

M. Sporn, T. Guilarte, K. Flanders, 2006, Molecular Cancer Therapeutics.

The hypothesis

Jiang Li, Thor D Stein, Jiang Li, 1990 .

Activation of the Nuclear Factor E2-Related Factor 2 Pathway by Novel Natural Products Halomadurones A–D and a Synthetic Analogue

Doug R. Braun, DelindaA . Johnson, Jeffrey A. Johnson, 2013, Marine drugs.

Beneficial Effects of Nrf2 Overexpression in a Mouse Model of Alexander Disease

DelindaA . Johnson, Jeffrey A. Johnson, A. Messing, 2012, The Journal of Neuroscience.

Structure activity relationship of phenolic diterpenes from Salvia officinalis as activators of the nuclear factor E2-related factor 2 pathway.

DelindaA . Johnson, Jeffrey A. Johnson, J. Fischedick, 2013, Bioorganic & medicinal chemistry.

Activation of Antioxidant Response Element in Mouse Primary Cortical Cultures with Sesquiterpene Lactones Isolated from Tanacetum parthenium

DelindaA . Johnson, Jeffrey A. Johnson, R. D. de Vos, 2012, Planta Medica.

Role of Nrf2-dependent ARE-driven antioxidant pathway in neuroprotection.

Jiang Li, DelindaA . Johnson, Jeffrey A. Johnson, 2007, Methods in molecular biology.

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

M. Mattson, N. Greig, Qian-sheng Yu, 2010, Journal of neurochemistry.

Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis.

S. Werner, DelindaA . Johnson, Jeffrey A. Johnson, 2010, Genes & development.

Neuronal sensitivity to kainic acid is dependent on the Nrf2‐mediated actions of the antioxidant response element

Y. Kan, DelindaA . Johnson, Jeffrey A. Johnson, 2006, Journal of neurochemistry.

Nuclear Factor E2-Related Factor 2-Dependent Antioxidant Response Element Activation by tert-Butylhydroquinone and Sulforaphane Occurring Preferentially in Astrocytes Conditions Neurons against Oxidative Insult

DelindaA . Johnson, Jeffrey A. Johnson, A. Kraft, 2004, The Journal of Neuroscience.

Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.

Y. Kan, DelindaA . Johnson, Jeffrey A. Johnson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

T. Murphy, DelindaA . Johnson, Jeffrey A. Johnson, 2003, The Journal of Neuroscience.

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

P. Kind, J. Tulloch, S. Chandran, 2022, Nature Communications.

Developmental exposure to methylmercury alters learning and induces depression-like behavior in male mice.

T. Hökfelt, DelindaA . Johnson, Jeffrey A. Johnson, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription

DelindaA . Johnson, Jeffrey A. Johnson, M. Calkins, 2010, Experimental Neurology.

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

DelindaA . Johnson, Jeffrey A. Johnson, A. Messing, 2008, The Journal of Neuroscience.

Human recombinant interferon-βSER and tamoxifen: growth suppressive effects for the human breast carcinoma MCF-7 grown in the athymic mouse

E. Borden, DelindaA . Johnson, V. Jordan, 2004, Breast Cancer Research and Treatment.

Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems*

J. Morrow, DelindaA . Johnson, Jeffrey A. Johnson, 2008, Journal of Biological Chemistry.

but Not for Wound Healing Are Essential for Skin Tumor Prevention Nrf Transcription Factors in Keratinocytes

T. A. Beyer, DelindaA . Johnson, Jeffrey A. Johnson, 2014 .

Activation of the Nrf2–ARE pathway in muscle and spinal cord during ALS-like pathology in mice expressing mutant SOD1

J. Resch, DelindaA . Johnson, Jeffrey A. Johnson, 2007, Experimental Neurology.

Gene expression analysis in mice with elevated glial fibrillary acidic protein and Rosenthal fibers reveals a stress response followed by glial activation and neuronal dysfunction.

Mark A. Smith, DelindaA . Johnson, Jeffrey A. Johnson, 2005, Human molecular genetics.

Rotenone‐induced caspase 9/3‐independent and ‐dependent cell death in undifferentiated and differentiated human neural stem cells

Jiang Li, Clive N Svendsen, Jiang Li, 2005, Journal of neurochemistry.

Microglial Activation and Antioxidant Responses Induced by the Parkinson’s Disease Protein α-Synuclein

DelindaA . Johnson, Jeffrey A. Johnson, S. Chasovskikh, 2012, Journal of Neuroimmune Pharmacology.

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

Y. Kan, Richard J Smeyne, DelindaA . Johnson, 2009, Proceedings of the National Academy of Sciences.

Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human.

Xiaoling Li, DelindaA . Johnson, Jeffrey A. Johnson, 2014, Antioxidants & redox signaling.

Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein

DelindaA . Johnson, A. Messing, Tracy L. Hagemann, 2009, Journal of neurochemistry.

Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro.

DelindaA . Johnson, Jeffrey A. Johnson, R. Jakel, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR-γ Agonist against MPTP

M. Emborg, DelindaA . Johnson, Jeffrey A. Johnson, 2013, PPAR research.

Cell‐specific overactivation of nuclear erythroid 2 p45‐related factor 2–mediated gene expression in myeloid cells decreases hepatic ischemia/reperfusion injury

S. Werner, DelindaA . Johnson, D. Foley, 2016, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Increased Alzheimer's disease–like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy

G. Joshi, DelindaA . Johnson, Jeffrey A. Johnson, 2015, Neurobiology of Aging.

The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis.

DelindaA . Johnson, Jeffrey A. Johnson, S. Amirahmadi, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Antioxidant responsive element activation by quinones: antioxidant responsive element target genes, role of PI3 kinase in activation.

Jiang Li, DelindaA . Johnson, Jeffrey A. Johnson, 2004, Methods in enzymology.

Activation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.

DelindaA . Johnson, Jeffrey A. Johnson, Tracy P. Williamson, 2012, Neurotoxicology.

Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress

R. Raines, DelindaA . Johnson, Jeffrey A. Johnson, 2019, The Journal of Biological Chemistry.

Astrocyte-Specific Overexpression of Nrf2 Delays Motor Pathology and Synuclein Aggregation throughout the CNS in the Alpha-Synuclein Mutant (A53T) Mouse Model

L. Gan, DelindaA . Johnson, Jeffrey A. Johnson, 2012, The Journal of Neuroscience.

Astrocyte-specific overexpression of Nrf2 protects striatal neurons from mitochondrial complex II inhibition.

DelindaA . Johnson, Jeffrey A. Johnson, M. Calkins, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Absence of Nrf2 or Its Selective Overexpression in Neurons and Muscle Does Not Affect Survival in ALS-Linked Mutant hSOD1 Mouse Models

S. Werner, L. Gan, DelindaA . Johnson, 2013, PloS one.

Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice

DelindaA . Johnson, W. Xu, G. Andrews, 2002, Journal of neurochemistry.

Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient.

S. Robinson, DelindaA . Johnson, V. Jordan, 1991, Drug metabolism and disposition: the biological fate of chemicals.

Increased Alzheimer's disease–like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy

G. Joshi, DelindaA . Johnson, Jeffrey A. Johnson, 2015, Neurobiology of Aging.

Nrf2, a multi‐organ protector?

DelindaA . Johnson, T. Stein, M. Calkins, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1G93A mice model

DelindaA . Johnson, Jeffrey A. Johnson, Marcelo R Vargas, 2011, Neurobiology of Disease.

Preferential expression of antioxidant response element mediated gene expression in astrocytes

R. Ng, T. Murphy, C. Honey, 2001, Journal of neurochemistry.

Selenium deficiency activates mouse liver Nrf2-ARE but vitamin E deficiency does not.

DelindaA . Johnson, Jeffrey A. Johnson, M. Freeman, 2008, Free radical biology & medicine.

The hypothesis

Jiang Li, Eka Swadiansa, DelindaA . Johnson, 1990 .