D. Helinski

发表

A haemoprotein with kinase activity encoded by the oxygen sensor of Rhizobium meliloti

M. Gilles-Gonzalez, G. Ditta, D. Helinski, 1991, Nature.

Heme biosynthesis in Rhizobium. Identification of a cloned gene coding for delta-aminolevulinic acid synthetase from Rhizobium meliloti.

G. Ditta, D. Helinski, S. Leong, 1982, The Journal of biological chemistry.

Firefly luciferase gene: structure and expression in mammalian cells

K. Wood, D. Helinski, S. Subramani, 1987, Molecular and cellular biology.

G. Ditta, D. Helinski, D. Finlay, 1985, Plasmid.

Isolation of Broad-Host-Range Replicons from Marine Sediment Bacteria

Michelle C. Y. Chang, D. Helinski, T. Mincer, 1998, Applied and Environmental Microbiology.

The parDE operon of the broad-host-range plasmid RK2 specifies growth inhibition associated with plasmid loss.

D. Helinski, R. C. Roberts, A. Ström, 1994, Journal of molecular biology.

ParE toxin encoded by the broad‐host‐range plasmid RK2 is an inhibitor of Escherichia coli gyrase

J. Pogliano, D. Helinski, I. Konieczny, 2002, Molecular microbiology.

Transcription and autoregulation of the stabilizing functions of broad‐host‐range plasmid RK2 in Escherichia coli, Agrobacterium tumefaciens and Pseudomonas aeruginosa

D. Helinski, R. C. Roberts, T. Davis, 1992, Molecular microbiology.

Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli.

K. Wood, D. Helinski, M. Deluca, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Aromatic aminotransferase activity and indoleacetic acid production in Rhizobium meliloti

G. Ditta, D. Helinski, B. L. Kittell, 1989, Journal of bacteriology.

The incC korB region of RK2 repositions a mini-RK2 replicon in Escherichia coli.

D. Helinski, Céline Verheust, 2007, Plasmid.

Inhibition of protein and RNA synthesis in Escherichia coli results in declustering of plasmid RK2.

D. Helinski, Shiyin Yao, A. Toukdarian, 2006, Plasmid.

Gyrase Inhibitors and Thymine Starvation Disrupt the Normal Pattern of Plasmid RK2 Localization in Escherichia coli

D. Helinski, Shiyin Yao, Erik P. Johnson, 2005, Journal of bacteriology.

Gene cloning and containment properties of plasmid Col E1 and its derivatives.

D. Helinski, K. Armstrong, V. Hershfield, 1977, Science.

Plasmid Incompatibility and Replication Control

D. Helinski, B. L. Kittell, 1993 .

Genetic Engineering: Principles and Methods

M. Olson, C. Anderson, D. Helinski, 2001, Genetic Engineering.

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

D. Helinski, D. Clewell, 1972, Journal of bacteriology.

Overlapping transcription of the nifA regulatory gene in Rhizobium meliloti.

C. H. Kim, G. Ditta, D. Helinski, 1986, Gene.

Complete Nucleotide Sequence of Birmingham IncPα Plasmids: Compilation and Comparative Analysis

Christopher M Thomas, D. Helinski, H. Schwab, 1994 .

Role of the parCBA Operon of the Broad-Host-Range Plasmid RK2 in Stable Plasmid Maintenance

D. Helinski, H. Schwab, C. Easter, 1998, Journal of bacteriology.

Plasmids isolated from marine sediment microbial communities contain replication and incompatibility regions unrelated to those of known plasmid groups

D. Helinski, T. Mincer, P. Sobecky, 1997, Applied and environmental microbiology.

Characterization of the stable maintenance properties of the par region of broad-host-range plasmid RK2

D. Helinski, P. Sobecky, C. Easter, 1996, Journal of bacteriology.

Mutations in the gene encoding the replication-initiation protein of plasmid RK2 produce elevated copy numbers of RK2 derivatives in Escherichia coli and distantly related bacteria.

F. Fang, D. Helinski, R. Durland, 1993, Gene.

Broad-host-range properties of plasmid RK2: importance of overlapping genes encoding the plasmid replication initiation protein TrfA

F. Fang, D. Helinski, Ferric C. Fang, 1991, Journal of bacteriology.

Involvement of the host initiator function dnaA in the replication of coliphage lambda.

D. Helinski, G. Węgrzyn, I. Konieczny, 1995, Genetics.

Escherichia coli dnaA gene function and bacteriophage λ replication

D. Helinski, G. Węgrzyn, A. Węgrzyn, 1998 .

Regulation of the switch from early to late bacteriophage lambda DNA replication.

D. Helinski, G. Węgrzyn, A. Herman-Antosiewicz, 2001, Microbiology.

Rhizobium meliloti genes required for nodule development are related to chromosomal virulence genes in Agrobacterium tumefaciens.

G. Ditta, D. Helinski, C. Douglas, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of 10 IncP plasmids: homology in the regions involved in plasmid replication

D. Helinski, T. Schmidhauser, D. Guiney, 1985, Journal of bacteriology.

Release of initiation control by a mutational alteration in the R6K pi protein required for plasmid DNA replication.

D. Helinski, D. Stalker, M. Filutowicz, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance

Christopher M Thomas, D. Helinski, R. Meyer, 1980, Journal of bacteriology.

Role of the pi initiation protein and direct nucleotide sequence repeats in the regulation of plasmid R6K replication.

D. Helinski, P. Mukhopadhyay, A. Greener, 1985, Basic life sciences.

Contained use of Bacteriophages: Risk Assessment and Biosafety Recommendations

D. Helinski, P. Herman, J. Mahillon, 2010 .

Immunoelectron microscopy of deoxyribonucleic acid in procaryotic cells.

S. Singer, D. Helinski, A. Toukdarian, 1992 .

Regions of broad-host-range plasmid RK2 involved in replication and stable maintenance in nine species of gram-negative bacteria

D. Helinski, T. Schmidhauser, 1985, Journal of bacteriology.

N-terminal truncated forms of the bifunctional π initiation protein express negative activity on plasmid R6K replication

D. Helinski, A. Greener, M. Filutowicz, 1990, Molecular and General Genetics MGG.

Purification and characterization of covalently closed replicative intermediates of ColEl DNA from Escherichia coli.

P. Williams, D. Helinski, S. Sato, 1977, Biochemistry.

DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1.

D. Kingsbury, D. Helinski, David T. Kingsbury, 1970, Biochemical and biophysical research communications.

Small circular DNA in Drosophila melanogaster

D. Helinski, S. Stanfield, 1976, Cell.

Chromogenic immunodetection of human serum albumin and alpha-L-fucosidase clones in a human hepatoma cDNA expression library.

D. Helinski, J. O'brien, J. D. de Wet, 1984, DNA.

A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli.

D. Helinski, Y. Kupersztoch, Yankel M. Kupersztoch, 1973, Biochemical and biophysical research communications.

Suppression of Co1E1 replication properties by the Inc P-1 plasmid RK2 in hybrid plasmids constructed in vitro.

D. Helinski, D. Figurski, R. Meyer, 1979, Journal of molecular biology.

Isolation and characterization of the recA gene of Rhizobium meliloti

D. Helinski, M. Better, 1983, Journal of bacteriology.

Separation of the minimal replication region of the F plasmid into a replication origin segment and a trans-acting segment

D. Helinski, A. Tolun, 2004, Molecular and General Genetics MGG.

Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid

D. Helinski, M. Lovett, 1976, Journal of bacteriology.

Bidirectional replication of the mini-ColE1 plasmid pVH51

D. Helinski, R. Sparks, R. Eichenlaub, 1979, Journal of bacteriology.

Nucleotide sequence of the region of an origin of replication of the antibiotic resistance plasmid R6K.

R. Kolter, D. Helinski, D. Stalker, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Replication of the broad-host-range plasmid RK2: direct measurement of intracellular concentrations of the essential TrfA replication proteins and their effect on plasmid copy number

D. Helinski, R. Durland, 1990, Journal of bacteriology.

Comparison of10IncPPlasmids: HomologyintheRegions Involved inPlasmid Replication

D. Helinski, T. Schmidhauser, D. Guiney, 1985 .

Cloning andCharacterization ofSmallCircular DNA fromChinese Hamster OvaryCells

D. Helinski, Sharon W. Stanfieldand, 1984 .

Measurement of Intracellular Concentrations of the Essential TrfA

D. Helinski, R. Durland, 2022 .

Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2

D. Helinski, R. C. Roberts, 1992, Journal of bacteriology.

Promoters of the broad host range plasmid RK2: analysis of transcription (initiation) in five species of gram-negative bacteria.

D. Helinski, A. Greener, S. Lehman, 1992, Genetics.

Transcription signals in a region essential for replication of plasmid R6K.

D. Helinski, A. Shafferman, 1985, Plasmid.

Isolation and properties of temperature-sensitive mutants of the trfA gene of the broad host range plasmid RK2.

D. Helinski, R. Durland, S. Valla, 1991, Plasmid.

Mutations in the trfA replication gene of the broad-host-range plasmid RK2 result in elevated plasmid copy numbers

F. Fang, D. Helinski, A. Toukdarian, 1990, Journal of bacteriology.

Characterization of colicinogenic factor E1 from a non-induced and a mitomycin C-induced Proteus strain

D. Helinski, W. Dewitt, 1965 .

Temperature-Sensitive Mutants for the Replication of Plasmids in Escherichia coli: Requirement for Deoxyribonucleic Acid Polymerase I in the Replication of the Plasmid ColE1

D. Kingsbury, D. Helinski, 1973 .

Isolation of supercoiled colicinogenic factor E 1 DNA sensitive to ribonuclease and alkali.

D. Sherratt, D. Helinski, D. Blair, 1972, Proceedings of the National Academy of Sciences of the United States of America.

The A protein of the tryptophan synthetase of Escherichia coli. Purification, crystallization, and composition studies.

C. Yanofsky, D. Helinski, U. Henning, 1962, The Journal of biological chemistry.

Symbiotic Nitrogen Fixation Genes of Rhizobium meliloti

G. Ditta, D. Helinski, S. Leong, 1983 .

F 1 sex factor of Escherichia coli. Size and purification in the form of a strand-specific relaxation complex of supercoiled deoxyribonucleic acid and protein.

D. Helinski, B. Kline, 1971, Biochemistry.

Peptide pattern studies on the wild-type A protein of the tryptophan synthetase of Escherichia coli.

C. Yanofsky, D. Helinski, 1962, Biochimica et biophysica acta.

Molecular vehicle properties of the broad host range plasmid RK2

D. Helinski, D. Figurski, R. Meyer, 1975, Science.

Structural properties of the beta origin of replication of plasmid R6K.

D. Helinski, A. Shafferman, 1983, The Journal of biological chemistry.

Characterization of Group B Colicin-Resistant Mutants of Escherichia coli K-12: Colicin Resistance and the Role of Enterochelin

K. Timmis, B. Stillman, D. Helinski, 2022 .

Nucleotide sequence based characterizations of two cryptic plasmids from the marine bacterium Ruegeria isolate PR1b.

S. Sykes, T. Shea, D. Helinski, 2003, Plasmid.

RELATIONSHIP BETWEEN COLICINOGENIC FACTORS E1 AND V AND AN F FACTOR IN ESCHERICHIA COLI

D. Helinski, P. Kahn, 1964, Journal of bacteriology.

Contribution of different segments of the par region to stable maintenance of the broad-host-range plasmid RK2

D. Helinski, P. Sobecky, C. Easter, 1997, Journal of bacteriology.

Physical and genetic studies with restriction endonucleases on the broad host-range plasmid RK2

D. Helinski, D. Figurski, R. Meyer, 1977, Molecular and General Genetics MGG.

Generation in vitro of deletions in the broad host range plasmid RK2 using phage Mu insertions and a restriction endonuclease.

D. Helinski, D. Figurski, D. Miller, 1976, Gene.

Genetic Engineering for Nitrogen Fixation

D. Helinski, R. Hardy, R. Valentine, 1977, Basic Life Sciences.

Supercoiled ColEl Deoxyribonucleic Acid and Protein in Escherichia coli

D. Helinski, And, '. DONB.CLEWELL, 2003 .

Unidirectional replication of the P-group plasmid RK2.

D. Helinski, R. Meyer, Richard J. Meyer, 1977, Biochimica et biophysica acta.

and interaction with the ParD antitoxin protein . Plasmid RK 2 toxin protein ParE : purification

D. Helinski, A. Ström, Erik P. Johnson, 1996 .

Purification and characterization of colicin E2 and colicin E3.

D. Helinski, H. Herschman, 1967, The Journal of biological chemistry.

Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti.

G. Ditta, D. Helinski, D. Corbin, 1980, Proceedings of the National Academy of Sciences of the United States of America.

A region of the broad-host-range plasmid RK2 causes stable in planta inheritance of plasmids in Rhizobium meliloti cells isolated from alfalfa root nodules

D. Helinski, R. C. Roberts, M. Weinstein, 1992, Journal of bacteriology.

Symbiotic pseudorevertants of Rhizobium meliloti ndv mutants

G. Ditta, D. Helinski, P. Nagpal, 1990, Journal of bacteriology.

Roundtable discussion of research priorities.

D. Helinski, R. Valentine, O. Šebek, 1982, Basic life sciences.

Cloning DNA from Rhizobium Meliloti Using a New Broad Host Range, Binary Vehicle System

G. Ditta, D. Helinski, D. Corbin, 1981 .

Mutations in direct repeat sequences and in a conserved sequence adjacent to the repeats result in a defective replication origin in plasmid R6K.

D. Helinski, M. Filutowicz, M. McEachern, 1985, Proceedings of the National Academy of Sciences of the United States of America.

The DNa-protein relaxation complex of the plasmid RK2: Location of the site-specific nick in the region of the proposed origin of transfer

D. Helinski, D. Guiney, 1979, Molecular and General Genetics MGG.

Temperature-sensitive mutants for the replication of plasmids in Escherichia coli. II. Properties of host and plasmid mutations.

D. Kingsbury, D. Helinski, D. Sieckmann, 1973, Genetics.

Complete nucleotide sequence of Birmingham IncP alpha plasmids. Compilation and comparative analysis.

Christopher M Thomas, D. Helinski, H. Schwab, 1994, Journal of molecular biology.

Comparative Study of the Events Associated with Colicin Induction

D. Helinski, H. Herschman, 1967, Journal of bacteriology.

Purification and characterization of colicin E1.

D. Helinski, S. Schwartz, S. A. Schwartz, 1971, The Journal of biological chemistry.

A Brief History of Plasmids

D. Helinski, 2022 .

Plasmids as vectors for gene cloning.

D. Helinski, 1977, Basic life sciences.

CHEMISTRY OF COLICINOGENIC FACTORS

D. Helinski, 1973 .

Activity of the replication terminus of plasmid R6K in hybrid replicons in Escherichia coli.

R. Kolter, D. Helinski, 1978, Journal of molecular biology.

Construction of a novel plasmid-phage hybrid: use of the hybrid to demonstrate ColE1 DNA replication in vivo in the absence of a ColE1-specified protein.

D. Helinski, M. Kahn, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Nicking activity of an endonuclease. I. Transfer ribonucleic acid complex of Escherichia coli.

D. Helinski, W. Goebel, 1970, Biochemistry.

Generation of higher multiple circular DNA forms in bacteria.

D. Helinski, W. Goebel, 1968, Proceedings of the National Academy of Sciences of the United States of America.

The Oxygen Sensor FixL of Rhizobium Membrane Protein Containing Four

D. Helinski, A. F. L. G. S. Ditta, 2022 .

Studies on the action of bovine serum albumin on aged rat livermitochondria.

D. Helinski, C. Cooper, 1960, The Journal of biological chemistry.

Chapter 18 – Genetic Control of Protein Structure

C. Yanofsky, D. Helinski, 1966 .

Supercoiled circular DNA-protein complex in Escherichia coli: purification and induced conversion to an opern circular DNA form.

D. Helinski, D. Clewell, 1969, Proceedings of the National Academy of Sciences of the United States of America.

Hypoosmotic adaptation in Rhizobium meliloti requires beta-(1----2)-glucan

G. Ditta, D. Helinski, T. Dylan, 1990, Journal of bacteriology.

Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans.

D. Helinski, D. Figurski, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Interaction Between Colicinogenic Factor V and the Integrated F Factor in an Hfr Strain of Escherichia coli

D. Helinski, P. Kahn, 1965, Journal of bacteriology.

[35] Use of the λ phage promoter PL to promote gene expression in hybrid plasmid cloning vehicles

D. Helinski, H. Bernard, 1979 .

Circular DNA forms of colicinogenic factors E1, E2 and E3 from Escherichia coli.

D. Helinski, M. Bazaral, Michael Bazaeal, 1968, Journal of molecular biology.

Mutational analysis of the Rhizobium meliloti nifA promoter

G. Ditta, D. Helinski, P. G. Agron, 1992, Journal of bacteriology.

Transient and Stable Expression of the Firefly Luciferase Gene in Plant Cells and Transgenic Plants

K. Wood, D. Helinski, D. Ow, 1986, Science.

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event.

D. Helinski, D. Clewell, D R Helinski, 1970, Biochemistry.

Relaxation complexes of plasmid DNA and protein. II. Characterization of the proteins associated with the unrelaxed and relaxed complexes of plasmid ColE1.

D. Helinski, M. Lovett, 1975, The Journal of biological chemistry.

Characterization of a mini-ColC1 plasmid

D. Helinski, H. Boyer, V. Hershfield, 1976, Journal of bacteriology.

Plasmid determined resistance to antibiotics: molecular properties of R factors.

D. Helinski, 1973, Annual review of microbiology.

Altered DNA-protein relaxation complex in a replication mutant of plasmid ColE1

D. Helinski, J. Collins, S. Yanofsky, 1978, Molecular and General Genetics MGG.

Replication of antibiotic resistance plasmid R6K DNA in vitro.

D. Helinski, M. Inuzuka, 1978, Biochemistry.

Unidirectional replication of plasmid ColE1 DNA

D. Helinski, L. Katz, M. Lovett, 1974, Nature.

Localization of the Naturally Occurring Plasmid ColE1 at the Cell Pole

D. Helinski, Shiyin Yao, A. Toukdarian, 2006, Journal of bacteriology.

Plasmids as vectors for gene cloning: past, present, and future use.

D. Helinski, 1982, Basic life sciences.

Bacterial plasmids: autonomous replication and vehicles for gene cloning.

D. Helinski, 1979, CRC critical reviews in biochemistry.

Plasmid ColEl as a molecular vehicle for cloning and amplification of DNA.

C. Yanofsky, D. Helinski, H. Boyer, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Common regulatory elements control symbiotic and microaerobic induction of nifA in Rhizobium meliloti.

G. Ditta, D. Helinski, E. Virts, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of initiation of DNA replication.

R. Kolter, D. Helinski, 1979, Annual review of genetics.

ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE.

C. Yanofsky, D. Helinski, U. Henning, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Correspondence between genetic data and the position of amino acid alteration in a proein.

C. Yanofsky, D. Helinski, 1962, Proceedings of the National Academy of Sciences of the United States of America.

The FixL protein of Rhizobium meliloti can be separated into a heme-binding oxygen-sensing domain and a functional C-terminal kinase domain.

G. Ditta, D. Helinski, E. Monson, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Plasmid RK2 ParB Protein: Purification and Nuclease Properties

A. Burgin, D. Helinski, H. Schwab, 1999, Journal of bacteriology.

Nucleotide sequence of the region of the origin of replication of the broad host range plasmid RK2

Christopher M Thomas, D. Helinski, D. Stalker, 2004, Molecular and General Genetics MGG.

Negative control of plasmid R6K replication: possible role of intermolecular coupling of replication origins.

D. Helinski, M. McEachern, P. Tooker, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Requirement of a plasmid-encoded protein for replication in vitro of plasmid R6K.

D. Helinski, M. Inuzuka, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Construction of plasmid R6K derivatives in vitro: characterization of the R6K replication region.

R. Kolter, D. Helinski, 1978, Plasmid.

Strand and site specificity of the relaxation event for the relaxation complex of the antibiotic resistance plasmid R6K.

D. Helinski, M. Lovett, Y. M. Kupersztoch-Portnoy, 1974, Biochemistry.

Bacterial Plasmids

D. Helinski, D R Helinski, S N Cohen, 1973, Science.

Characterization of multiple circular DNA forms of colicinogenic factor E-1 from Proteus mirabilis.

D. Helinski, M. Bazaral, 1968, Biochemistry.

Structural relationships among rhizobium meliloti symbiotic promoters

G. Ditta, D. Helinski, D. Corbin, 1983, Cell.

Stimulation by Cyclic Adenosine Monophosphate of Plasmid Deoxyribonucleic Acid Replication and Catabolite Repression of the Plasmid Deoxyribonucleic Acid-Protein Relaxation Complex

D. Kingsbury, D. Helinski, L. Katz, 1973, Journal of bacteriology.

Plasmids in Bacteria

Stanley N Cohen, D. Helinski, A. Hollaender, 1985, Springer US.

Breaks induced in supercoiled colicinogenic factor E1 DNA as a result of the decay of incorporated tritium.

D. Helinski, Y. M. Kupersztoch-Portroy, 1974, Biochimica et biophysica acta.

The ndvA gene product of Rhizobium meliloti is required for beta-(1----2)glucan production and has homology to the ATP-binding export protein HlyB

G. Ditta, D. Helinski, D. O’brochta, 1988, Journal of bacteriology.

The effects of mutation on the composition and properties of the A protein of Escherichia coli tryptohan synthetase.

C. Yanofsky, D. Helinski, B. Maling, 1961, Cold Spring Harbor symposia on quantitative biology.

Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda pL promoter.

H. K. Das, C. Yanofsky, N. Franklin, 1979, Gene.

Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K

R. Kolter, D. Helinski, M. Inuzuka, 1978, Cell.

Strand-specific supercoiled DNA-protein relaxation complexes: comparison of the complexes of bacterial plasmids ColE1 and ColE2.

D. Helinski, D. Blair, D. Clewell, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Deletion analysis of Rhizobium meliloti symbiotic promoters

G. Ditta, D. Helinski, M. Better, 1985, The EMBO journal.

Relaxation complexes of plasmid DNA and protein. I. Strand-specific association of protein and DNA in the relaxed complexes of plasmids ColE1 and ColE2.

D. Helinski, D. Blair, 1975, The Journal of biological chemistry.

Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2.

R. Kolter, D. Helinski, E. Remaut, 1979, Methods in enzymology.

Functional analysis of two putative chromosomal replication origins from Pseudomonas aeruginosa.

D. Helinski, Shiyin Yao, A. Toukdarian, 2006, Plasmid.

A Brief History of Plasmids

D. Helinski, 2022, EcoSal Plus.

Plasmid R6K DNA replication. III. Regulatory properties of the pi initiation protein.

R. Kolter, D. Helinski, D. Stalker, 1982, Journal of molecular biology.

Plasmid R6K DNA replication. I. Complete nucleotide sequence of an autonomously replicating segment.

R. Kolter, D. Helinski, D. Stalker, 1982, Journal of molecular biology.

Direct repeats of the F plasmid incC region express F incompatibility

D. Helinski, A. Tolun, 1981, Cell.

Sturcture-Function Relationships in Essential Regions for Plasmid Replication

R. Kolter, D. Helinski, D. Stalker, 1981 .

Replication of a bacterial plasmid and an episome in Escherichia coli.

D. Helinski, M. Bazaral, 1970, Biochemistry.

Bidirection replication from a unique origin in a mini-F plasmid.

D. Helinski, D. Figurski, R. Eichenlaub, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Plasmid ColE1 DNA replication in Escherichia coli strains temperature-sensitive for DNA replication

D. Helinski, J. Collins, P. Williams, 2004, Molecular and General Genetics MGG.

Replication Control and Other Stable Maintenance Mechanisms of Plasmids

D. Helinski, A. Toukdarian, A. Novick, 1999 .

Structure and Evolution

David A. Jackson, Don B. Clewell, Stanley N Cohen, 1985 .

Broad-host-range plasmid cloning vectors for gram-negative bacteria.

G. Ditta, D. Helinski, T. Schmidhauser, 1988, Biotechnology.

Cloning and characterization of small circular DNA from Chinese hamster ovary cells

D. Helinski, D R Helinski, S W Stanfield, 1984, Molecular and cellular biology.

Relaxation complexes of poasmid DNA and protein. III. Association of protein with the 5' terminus of the broken DNA strand in the relaxed complex of plasmid ColE1.

D. Helinski, D. Guiney, 1975, The Journal of biological chemistry.

Relaxation complexes of plasmids ColE1 and ColE2: unique site of the nick in the open circular DNA of the relaxed complexes.

D. Helinski, M. Lovett, D. Guiney, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Replication of an origin-containing derivative of plasmid RK 2 dependent on a plasmid function provided in trans ( plasmid replication / replication origin / trans-complementation / broad host range / gene cloning )

D. Helinski, David H. Flgurski, 2022 .

Endonuclease I of Proteus mirabilis. Properties of the noncomplexed and transfer ribonucleic acid-complexed forms of the enzyme.

D. Helinski, W. Goebel, 1971, The Journal of biological chemistry.

Activity in vitro of three replication origins of the antibiotic resistance plasmid RSF1040.

D. Helinski, N. Inuzuka, M. Inuzuka, 1980, The Journal of biological chemistry.

Bidirectional replication of plasmid R6K DNA in Escherichia coli; correspondence between origin of replication and position of single-strand break in relaxed complex.

D. Helinski, R. Sparks, M. Lovett, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Effect of Rec− Mutations on the Activity of Colicinogenic Factors

D. Helinski, H. Herschman, 1967, Journal of bacteriology.

Properties of the Relaxation Complexes of Supercoiled Deoxyribonucleic Acid and Protein of the R Plasmids R64, R28K, and R6K

G. L. Miklos, D. Helinski, Y. M. Kupersztoch-Portnoy, 1974, Journal of bacteriology.

Effect of Inhibitors of Ribonucleic Acid and Protein Synthesis on the Cyclic Adenosine Monophosphate Stimulation of Plasmid ColE1 Replication

D. Helinski, L. Katz, 1974, Journal of bacteriology.

Positive and negative roles of an initiator protein at an origin of replication.

D. Helinski, M. Filutowicz, M. McEachern, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Autorepressor properties of the pi-initiation protein encoded by plasmid R6K

Marcin Filutowicz, George Davis, Alan Greener, 1985, Nucleic Acids Res..

Binding of purified wild-type and mutant pi initiation proteins to a replication origin region of plasmid R6K.

D. Helinski, M. Filutowicz, E. Uhlenhopp, 1986, Journal of molecular biology.

DNA segments of the IncX plasmid R485 determining replication and incompatibility with plasmid R6K.

D. Helinski, D. Stalker, 1985, Plasmid.

Plasmid R6K DNA replication. II. Direct nucleotide sequence repeats are required for an active gamma-origin.

R. Kolter, D. Helinski, 1982, Journal of molecular biology.

GENETIC STRUCTURE OF A PLASMID REPLICON

R. Kolter, D. Helinski, D. Stalker, 1982 .

The replication initiation protein of the broad-host-range plasmid RK2 is activated by the ClpX chaperone.

D. Helinski, I. Konieczny, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Role of TrfA and DnaA Proteins in Origin Opening during Initiation of DNA Replication of the Broad Host Range Plasmid RK2*

D. Helinski, A. Blasina, K. Doran, 1997, The Journal of Biological Chemistry.

Iteron inhibition of plasmid RK2 replication in vitro: evidence for intermolecular coupling of replication origins as a mechanism for RK2 replication control.

D. Helinski, B. L. Kittell, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Multicopy plasmids are clustered and localized in Escherichia coli

Donald R. Helinski, J. Pogliano, D. Helinski, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The Plasmid RK2 Initiation Protein Binds to the Origin of Replication as a Monomer (*)

D. Helinski, A. Toukdarian, S. Perri, 1996, The Journal of Biological Chemistry.

Comparison of the Tryptophan Synthetase α Subunits of Several Species of Enterobacteriaceae

C. Yanofsky, T. Creighton, D. Helinski, 1966 .

Introduction to Plasmids: a Selective View of Their History

D. Helinski, 2004 .

Different relative importances of the par operons and the effect of conjugal transfer on the maintenance of intact promiscuous plasmid RK2

D. Helinski, D. Figurski, R. C. Roberts, 1995, Journal of bacteriology.

Genetic characterization of the stabilizing functions of a region of broad-host-range plasmid RK2

D. Helinski, R. Burioni, R. C. Roberts, 1990, Journal of bacteriology.

Aromatic Amino Acid Aminotransferases of Azospirillum Lipoferum and Their Possible Involvement in IAA Biosynthesis

U. Klingmüller, D. Helinski, B. L. Kittell, 1988 .

Analysis of mutations in trfA, the replication initiation gene of the broad-host-range plasmid RK2

J. Lin, D. Helinski, 1992, Journal of bacteriology.

The ndvB locus of Rhizobium meliloti encodes a 319-kDa protein involved in the production of beta-(1----2)-glucan.

G. Ditta, D. Helinski, L. Ielpi, 1990, The Journal of biological chemistry.

Heme Biosynthesis in Rhizobium

D. Helinski, Gary, Ditta, 2001 .

Heterogeneous circular DNA elements in vegetative cultures of Bacillus megaterium.

D. Helinski, B. Carlton, 1969, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and repair of RNA-containing supercoiled plasmid ColE1 DNA in Escherichia coli.

P. Williams, D. Helinski, D. Blair, 1982, Plasmid.

Cyclic Adenosine Monophosphate Stimulation of Plasmid ColEl Replication

D. Helinski, L. Katz, 2022 .

Sequence Analysis of a 101-Kilobase Plasmid Required for Agar Degradation by a MicroscillaIsolate

S. Sykes, T. Shea, D. Helinski, 2001, Applied and Environmental Microbiology.

A genetic and biochemical analysis of second site reversion.

C. Yanofsky, D. Helinski, 1963, The Journal of biological chemistry.

A multifunctional plasmid-encoded replication initiation protein both recruits and positions an active helicase at the replication origin

D. Helinski, I. Konieczny, A. Toukdarian, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The Oxygen Sensor Protein, FixL, of Rhizobium meliloti

G. Ditta, D. Helinski, E. Monson, 1995, The Journal of Biological Chemistry.

Regulation of the switch from early to late bacteriophage λ DNA replication

ska, D. Helinski, A. Herman-Antosiewicz, 2022 .

A Specific Region in the N Terminus of a Replication Initiation Protein of Plasmid RK2 Is Required for Recruitment of Pseudomonas aeruginosa DnaB Helicase to the Plasmid Origin*

D. Helinski, A. Toukdarian, Zhenping Zhong, 2003, Journal of Biological Chemistry.

Plasmid host-range: restrictions to F replication in Pseudomonas.

D. Helinski, A. Toukdarian, Zhenping Zhong, 2005, Plasmid.

Interactions of DnaA Proteins from Distantly Related Bacteria with the Replication Origin of the Broad Host Range Plasmid RK2*

D. Helinski, R. Caspi, I. Konieczny, 2000, The Journal of Biological Chemistry.

Oxygen regulation of expression of nitrogen fixation genes in Rhizobium meliloti.

G. Ditta, D. Helinski, P. G. Agron, 1994, Research in microbiology.

Plasmid RK2 toxin protein ParE: purification and interaction with the ParD antitoxin protein

D. Helinski, A. Strøm, A. R. Strøm, 1996, Journal of bacteriology.

Characteristics and significance of DNA binding activity of plasmid stabilization protein ParD from the broad host-range plasmid RK2.

D. Helinski, R. C. Roberts, C. Spangler, 1993, The Journal of biological chemistry.

Isolation ofSupercoiled Colicinogenic Factor E1DNA Sensitive toRibonuclease andAlkali (chloramphenicol/Escherichia coli/supercoiled DNA/rifampicin)

D. Helinski, D. Blair, D. J. SHERRATTt, 1972 .

[1] Cloning firefly luciferase

K. Wood, D. Helinski, M. Deluca, 1986 .

Clustering of nitrogen fixation (nif) genes in Rhizobium meliloti

G. Ditta, D. Helinski, D. Corbin, 1982, Journal of bacteriology.

A 50-kb plasmid rich in mobile gene sequences isolated from a marine micrococcus.

T. Shea, D. Helinski, R. Caspi, 2002, Plasmid.

Firefly luciferase as a reporter enzyme for measuring gene expression in vegetative and symbiotic Rhizobium meliloti and other gram-negative bacteria.

D. Helinski, M. Deluca, A. Palomares, 1989, Gene.

CLONING OF LYSOSOMAL GENES

D. Helinski, A. Fluharty, T. Warner, 1984 .

Copy-up mutants of the plasmid RK2 replication initiation protein are defective in coupling RK2 replication origins.

D. Helinski, A. Blasina, A. Toukdarian, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mutants of the two-component regulatory protein FixJ of Rhizobium meliloti that have increased activity at the nifA promoter.

G. Ditta, D. Helinski, A. Lois, 1993, Gene.

TrfA dimers play a role in copy-number control of RK2 replication.

D. Helinski, A. Toukdarian, 1998, Gene.

Replication from one of the three origins of the plasmid R6K requires coupled expression of two plasmid-encoded proteins.

D. Helinski, P. Mukhopadhyay, M. Filutowicz, 1986, The Journal of biological chemistry.

Multiple mechanisms generate extrachromosomal circular DNA in Chinese hamster ovary cells.

D. Helinski, S. Stanfield, 1986, Nucleic acids research.

Interactions of plasmid-encoded replication initiation proteins with the origin of DNA replication in the broad host range plasmid RK2.

D. Helinski, A. Toukdarian, S. Perri, 1991, The Journal of biological chemistry.

Host-specific effects of the korA-korB operon and oriT region on the maintenance of miniplasmid derivatives of broad host-range plasmid RK2.

D. Bechhofer, D. Helinski, D. Figurski, 1989, Plasmid.

Replication of derivatives of the broad host range plasmid RK2 in two distantly related bacteria.

D. Helinski, M. Filutowicz, T. Schmidhauser, 1983, Plasmid.

Oxygen regulation of nifA transcription in vitro.

G. Ditta, D. Helinski, P. G. Agron, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Symbiotic Expression of Rhizobium meliloti Nitrogen Fixation Genes Is Regulated by Oxygen

D. Helinski, P. G. Agron, 1995 .

A pilot study of orlistat treatment in obese, non‐alcoholic steatohepatitis patients

D. Helinski, P. Hayashi, S. Harrison, 2004, Alimentary pharmacology & therapeutics.

A Critical DnaA Box Directs the Cooperative Binding of theEscherichia coli DnaA Protein to the Plasmid RK2 Replication Origin*

D. Helinski, K. Doran, I. Konieczny, 1999, The Journal of Biological Chemistry.

Essentiality of the three carboxyl-terminal amino acids of the plasmid RK2 replication initiation protein TrfA for DNA binding and replication activity in gram-negative bacteria.

D. Helinski, J. L. Cereghino, 1993, The Journal of biological chemistry.

The sequence encoding the 43-kilodalton trfA protein is required for efficient replication or maintenance of minimal RK2 replicons in Pseudomonas aeruginosa.

D. Helinski, R. Durland, 1987, Plasmid.

Isolation and characterization of DNA-binding mutants of a plasmid replication initiation protein utilizing an in vivo binding assay.

D. Helinski, A. Toukdarian, J. L. Cereghino, 1994, Plasmid.

Effect ofGrowth Conditions on theFormation oftheRelaxation Complex ofSupercoiled ColEl Deoxyribonucleic AcidandProtein in Escherichia coli

D. Helinski, D. Clewell, 1972 .

Plasmid DNA replication: RK2- and R6K-encoded trans-acting factors and their sites of action.

R. Kolter, D. Helinski, D. Stalker, 1979, Cold Spring Harbor symposia on quantitative biology.

Genetic Engineering

T. Maniatis, C. Anderson, D. Helinski, 1990, Genetic Engineering.

Temperature-sensitive mutants for the replication of plasmids in Escherichia coli: requirement for deoxyribonucleic acid polymerase I in the replication of the plasmid ColE 1 .

D. Kingsbury, D. Helinski, 1973, Journal of Bacteriology.

A broad host range replicon with different requirements for replication initiation in three bacterial species

D. Helinski, R. Caspi, I. Konieczny, 2001, The EMBO journal.

Host‐dependent requirement for specific DnaA boxes for plasmid RK2 replication

D. Helinski, K. Doran, I. Konieczny, 1999, Molecular microbiology.

Replication Origin of the Broad Host Range Plasmid RK2

D. Helinski, K. Doran, I. Konieczny, 1998, The Journal of Biological Chemistry.

Helicase Delivery and Activation by DnaA and TrfA Proteins during the Initiation of Replication of the Broad Host Range Plasmid RK2*

D. Helinski, I. Konieczny, Donald R. Helinski, 1997, The Journal of Biological Chemistry.

Temperature-sensitive mutants for the replication of plasmids in Escherichia coli. I. Isolation and specificity of host and plasmid mutations.

D. Kingsbury, D. Helinski, 1973, Genetics.

ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE.

C. Yanofsky, D. Helinski, U. Henning, 1964, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of phosphorylation‐deficient mutants of the Rhizobium Meliloti two‐component regulatory protein, FixJ

G. Ditta, D. Helinski, E. Monson, 1992, Molecular microbiology.

Existence of the colicinogenic factor-sex factor ColI-b-P9 as a supercoiled circular DNA-protein relaxation complex.

D. Helinski, D. Clewell, D. Helinski, 1970, Biochemical and biophysical research communications.

Replication of Colicinogenic Factor El in Escherichia coli

D. Sherratt, D. Helinski, 1973 .

Circular DNA forms of a bacterial sex factor.

D. Helinski, T. F. Roth, F. T. Hickson, 1967, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for circular DNA forms of a bacterial plasmid.

D. Helinski, T. F. Roth, 1967, Proceedings of the National Academy of Sciences of the United States of America.