A. Rohou

发表

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Hui Xu, Tianbo Li, A. Rohou, 2019 .

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

John L Rubinstein, Alexis Rohou, Anna Zhou, 2015, bioRxiv.

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

N. Grigorieff, J. Rubinstein, John E. Walker, 2015, bioRxiv.

Frealix: model-based refinement of helical filament structures from electron micrographs.

N. Grigorieff, A. Rohou, 2014, Journal of structural biology.

Peptide dimer structure in an Aβ(1–42) fibril visualized with cryo-EM

K. Lasker, N. Grigorieff, A. Rohou, 2015, Proceedings of the National Academy of Sciences.

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

N. Grigorieff, A. Rohou, 2015, bioRxiv.

Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab

G. Nakamura, A. Rohou, C. Arthur, 2020, Science.

Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration

M. Ultsch, E. Green, A. Rohou, 2022, Nature Communications.

cisTEM: User-friendly software for single-particle image processing

Alexis Rohou, Nikolaus Grigorieff, Timothy Grant, 2017, bioRxiv.

Insecticidal toxins from black widow spider venom

A. Rohou, Y. Ushkaryov, J. Nield, 2007, Toxicon : official journal of the International Society on Toxinology.

α-Latrotoxin and Its Receptors

A. Rohou, S. Sugita, Y. Ushkaryov, 2008 .

alpha-Latrotoxin and its receptors.

A. Rohou, S. Sugita, Y. Ushkaryov, 2008, Handbook of experimental pharmacology.

Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub

Peter J Lewis, Alexis Rohou, Jon Marles-Wright, 2008, Science.

Structure of the SLC4 transporter Bor1p in an inward‐facing conformation

N. Coudray, D. Stokes, A. Rohou, 2016, Protein science : a publication of the Protein Society.

Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase

C. Robinson, J. Rubinstein, A. Rohou, 2016, Nature.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

Alexis Rohou, Christopher P. Arthur, Jun Chen, 2019, Cell.

! 1 ! Structure and conformational states of the bovine mitochondrial ATP synthase by cryo

N. Grigorieff, J. Rubinstein, A. Rohou, 2015 .

Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9

A. Rohou, A. Estevez, M. Holliday, 2018, The Journal of Biological Chemistry.

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

Alexis Rohou, Nikolaus Grigorieff, N. Grigorieff, 2015, bioRxiv.

Four-Dimensional Cryo Electron Microscopy at Quasi Atomic Resolution: "IMAGIC 4D"

Michael Schatz, Marin van Heel, Rodrigo Villares Portugal, 2012 .

Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors

M. Volgraf, A. Rohou, C. Arthur, 2022, bioRxiv.

Structural basis of α-scorpion toxin action on Nav channels

A. Rohou, C. Arthur, C. Ciferri, 2019, Science.

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

Hui Xu, Tianbo Li, A. Rohou, 2019, Cell.

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation

A. Rohou, C. Arthur, M. Holliday, 2019, Nature Communications.

A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel

M. Volgraf, Tianbo Li, A. Rohou, 2020, Neuron.

Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy.

M. Volgraf, A. Rohou, Jun Chen, 2021, Journal of medicinal chemistry.

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

Simon S. Gao, J. Elstrott, M. Volgraf, 2021, The Journal of experimental medicine.

Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry

A. Rohou, C. Arthur, C. Ciferri, 2021, Cell.

Structural basis of alpha-scorpion toxin action on Navchannels.

A. Rohou, C. Arthur, C. Ciferri, 2019 .

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation

A. Rohou, C. Arthur, M. Holliday, 2019, Nature Communications.

Helical assembly of the CARD9 CARD

A. Rohou, C. Arthur, M. Holliday, 2019 .

Peptide dimer structure in an Aβ(1–42) fibril visualized with cryo-EM

N. Grigorieff, A. Rohou, M. Fändrich, 2015, Proceedings of the National Academy of Sciences.

Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub

M. van Heel, A. Rohou, S. Firbank, 2008, Science.

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

N. Grigorieff, J. Rubinstein, A. Rohou, 2015, bioRxiv.

cisTEM, user-friendly software for single-particle image processing

N. Grigorieff, A. Rohou, T. Grant, 2018, eLife.

cisTEM, user-friendly software for single-particle image processing

N. Grigorieff, A. Rohou, T. Grant, 2018, eLife.

Frealix: model-based refinement of helical filament structures from electron micrographs.

N. Grigorieff, A. Rohou, 2014, Journal of structural biology.