A. Sato-Otsubo

发表

Integrated molecular analysis of clear-cell renal cell carcinoma

H. Aburatani, H. Kume, Y. Homma, 2013, Nature Genetics.

Dynamics of clonal evolution in myelodysplastic syndromes

S. Miyano, T. LaFramboise, Y. Shiraishi, 2016, Nature Genetics.

Frequent pathway mutations of splicing machinery in myelodysplasia

S. Sugano, Yutaka Suzuki, S. Miyano, 2011, Nature.

Genome-Wide Analysis of Ocular Adnexal Lymphoproliferative Disorders Using High-Resolution Single Nucleotide Polymorphism Array.

S. Ogawa, Yusuke Sato, A. Sato-Otsubo, 2015, Investigative ophthalmology & visual science.

anemia Extensive gene deletions in Japanese patients with Diamond-Blackfan

S. Ogawa, T. Morio, K. Yamaguchi, 2012 .

Extensive gene deletions in Japanese patients with Diamond-Blackfan anemia.

S. Ogawa, T. Morio, K. Yamaguchi, 2012, Blood.

Title Aberrant splicing and defective mRNA production induced bysomatic spliceosome mutations in myelodysplasia

M. Cazzola, S. Miyano, Y. Shiraishi, 2019 .

Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

M. Cazzola, S. Miyano, Y. Shiraishi, 2018, Nature Communications.

Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia

N. Kenmochi, S. Miyano, Y. Shiraishi, 2017, Haematologica.

Novel TENM3–ALK fusion is an alternate mechanism for ALK activation in neuroblastoma

S. Miyano, S. Ogawa, Motohiro Kato, 2022, Oncogene.

Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

Masao Nagasaki, Satoru Miyano, Yuichi Shiraishi, 2012, Nature Genetics.

Mutational landscape and clonal architecture in grade II and III gliomas

Satoru Miyano, Yuichi Shiraishi, Toshihiko Wakabayashi, 2015, Nature Genetics.

Gene expression and risk of leukemic transformation in myelodysplasia.

Satoru Miyano, Yuichi Shiraishi, Kenichi Chiba, 2017, Blood.

Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation.

S. Ogawa, T. Shiina, M. Satake, 2018, Blood.

Older patients with normal karyotype acute myeloid leukemia have a higher rate of genomic changes compared to young patients as determined by SNP array analysis.

S. Ogawa, T. Haferlach, A. Nagler, 2012, Leukemia research.

Genetic features of precursor B‐cell phenotype Burkitt leukemia with IGH‐ MYC rearrangement

Motohiro Kato, A. Sato-Otsubo, S. Ito, 2021, Cancer reports.

Aggressive transformation of juvenile myelomonocytic leukemia associated with duplication of oncogenic KRAS due to acquired uniparental disomy.

S. Ogawa, R. Hanada, Motohiro Kato, 2013, The Journal of pediatrics.

Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

Nicola K. Wilson, H. Aburatani, B. Göttgens, 2022, Nature Communications.

Different Mutant Splicing Factors Cause Distinct Missplicing Events and Give Rise to Different Clinical Phenotypes in Myelodysplastic Syndromes

M. Cazzola, S. Miyano, Y. Shiraishi, 2015 .

Adult T‐cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth

S. Ogawa, K. Nakano, K. Yamaguchi, 2013, Cancer science.

Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia.

S. Ogawa, H. Inoko, T. Shiina, 2016, Experimental hematology.

NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia

K. Okamura, S. Ogawa, Motohiro Kato, 2021, Blood advances.

In Analogy to AML, MDS Can be Sub-Classified By Ancestral Mutations

S. Miyano, T. LaFramboise, Y. Shiraishi, 2014 .

Brief Report Results and Discussion

S. Ogawa, Y. Hayashi, A. Sato-Otsubo, 2022 .

Genomic analysis of two rare cases of pediatric Ph‐positive T‐ALL

S. Ogawa, Motohiro Kato, A. Sato-Otsubo, 2021, Pediatric blood & cancer.

Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism

H. Aburatani, S. Miyano, Hiromichi Suzuki, 2022, Oncogene.

Quantitative assessment of copy number alterations by liquid biopsy for neuroblastoma

Motohiro Kato, J. Takita, A. Sato-Otsubo, 2022, Genes, chromosomes & cancer.

Mutational Spectrum Analysis of Interesting Correlation and Interrelationship Between RNA Splicing Pathway and Commonly Targeted Genes in Myelodysplastic Syndrome

S. Miyano, Y. Shiraishi, S. Ogawa, 2011 .

Recurrent Mutations of Multiple Components of Cohesin Complex in Myeloid Neoplasms

S. Ishikawa, H. Aburatani, K. Shirahige, 2012 .

Integrated molecular analysis of adult T cell leukemia/lymphoma

H. Aburatani, O. Nureki, T. Kawaguchi, 2015, Nature Genetics.

Identification of Two New DBA Genes, RPS27 and RPL27, by Whole-Exome Sequencing in Diamond-Blackfan Anemia Patients

S. Miyano, Y. Shiraishi, K. Chiba, 2012 .

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma

O. Nureki, S. Miyano, Y. Shiraishi, 2014, Nature Genetics.

Overexpression of miR-26a-2 in human liposarcoma is correlated with poor patient survival

S. Ogawa, A. Sato-Otsubo, J. Said, 2013, Oncogenesis.

BRCA1 alterations with additional defects in DNA damage response genes may confer chemoresistance to BRCA‐like breast cancers treated with neoadjuvant chemotherapy

S. Ogawa, M. Kurosumi, Yusuke Sato, 2017, Genes, chromosomes & cancer.

Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemotherapy

S. Ogawa, M. Kurosumi, A. Sato-Otsubo, 2013, BMC Cancer.

Title Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells(

S. Ogawa, S. Muro, T. Hirai, 2017 .

Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells

S. Ogawa, S. Muro, T. Hirai, 2014, Stem cell reports.

Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

S. Miyano, F. Thol, A. Ganser, 2014, Nature Communications.

Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia

S. Miyano, Y. Shiraishi, S. Ogawa, 2014, Leukemia.

Copy number alteration analysis for neuroblastoma using droplet digital polymerase chain reaction

T. Morio, J. Takita, M. Takagi, 2021, Pediatrics international : official journal of the Japan Pediatric Society.

Recurrent somatic mutations underlie corticotropin-independent Cushing’s syndrome

O. Nureki, H. Kume, Y. Homma, 2014, Science.

Characterization of genetic lesions in rhabdomyosarcoma using a high‐density single nucleotide polymorphism array

S. Ogawa, Y. Hayashi, R. Hanada, 2013, Cancer science.

Single-nucleotide polymorphism array karyotyping in clinical practice: where, when, and how?

S. Ogawa, A. Sato-Otsubo, M. Sanada, 2012, Seminars in oncology.

Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.

Makoto Yamagishi, Seishi Ogawa, Kazunari Yamaguchi, 2012, Cancer cell.

Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants

S. Miyano, Y. Shiraishi, K. Chiba, 2020, Communications Biology.

Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants

S. Miyano, Y. Shiraishi, K. Chiba, 2020, Communications biology.

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

S. Miyano, T. Shimamura, Y. Shiraishi, 2020, npj Precision Oncology.

Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia.

S. Miyano, B. Dumitriu, Y. Shiraishi, 2015, The New England journal of medicine.

Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis

S. Ogawa, A. Sato-Otsubo, M. Sanada, 2012, International Journal of Hematology.

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

J. Yokota, Y. Totoki, T. Kohno, 2013, Genes, chromosomes & cancer.

Genetic differences between Asian and Caucasian chronic lymphocytic leukemia

S. Ogawa, A. Sato-Otsubo, H. Koeffler, 2013, International journal of oncology.

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.

O. Nureki, S. Miyano, T. Shibata, 2015, Blood.

The landscape of somatic mutations in Down syndrome–related myeloid disorders

S. Miyano, Y. Shiraishi, K. Chiba, 2013, Nature Genetics.

High-resolution genomic copy number profiling of primary intraocular lymphoma by single nucleotide polymorphism microarrays

S. Ogawa, M. Mochizuki, A. Sato-Otsubo, 2014, Cancer science.

Cell Therapy Using Human Induced Pluripotent Stem Cell‐Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice

S. Yamanaka, Kazutoshi Takahashi, S. Ogawa, 2015, Stem cells translational medicine.

Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.

S. Yamanaka, Kazutoshi Takahashi, S. Ogawa, 2012, Blood.

Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.

S. Ogawa, Yusuke Sato, A. Sato-Otsubo, 2011, Blood.

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.

N. Kenmochi, S. Miyano, Y. Shiraishi, 2018, American journal of human genetics.

Loss of function mutations in RPL27 and RPS27 identified by whole‐exome sequencing in Diamond‐Blackfan anaemia

N. Kenmochi, S. Miyano, Y. Shiraishi, 2015, British journal of haematology.

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

O. Nureki, S. Miyano, Y. Totoki, 2016, Blood.

ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion

S. Ogawa, T. Haferlach, D. Liang, 2018, Haematologica.

Evolutionary basis of HLA-DPB 1 alleles affects acute GVHD in unrelated donor stem cell transplantation Running title : Evolutionary basis of HLA-DPB 1 and acute GVHD

Shunichi Kato, Takashi Shiina, Seishi Ogawa, 2017 .

High-risk HLA alleles for severe acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation

S. Ogawa, T. Shiina, K. Matsuo, 2016, Haematologica.

Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome.

S. Miyano, Y. Shiraishi, S. Ogawa, 2013, Blood.

Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population.

T. Kawaguchi, S. Ogawa, I. Komuro, 2013, American journal of human genetics.

Toll-like receptor genetic variations in bone marrow transplantation

I. Hanamura, S. Ogawa, A. Sato-Otsubo, 2017, Oncotarget.

Favorable outcome of patients who have 13q deletion: a suggestion for revision of the WHO ‘MDS-U’ designation

S. Ogawa, A. Sato-Otsubo, M. Sanada, 2012, Haematologica.

Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation.

G. Kennedy, S. Ogawa, H. Inoko, 2015, Blood.

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1

A. Sato-Otsubo, N. Haginoya, Mayumi Kitagawa, 2023, Cancer Cell International.

HapMap SNP Scanner: an online program to mine SNPs responsible for cell phenotype.

S. Ogawa, S. Riddell, A. Sato-Otsubo, 2012, Tissue antigens.

Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma

J. Yokota, T. Kohno, S. Ogawa, 2012, Genes, chromosomes & cancer.

model for dissecting somatic mosaicism and drug discovery Induced pluripotent stem cells from CINCA syndrome patients as a

S. Yamanaka, Kazutoshi Takahashi, S. Ogawa, 2013 .

Genetic features of B‐cell lymphoblastic lymphoma with TCF3‐PBX1

S. Ogawa, M. Takagi, A. Sato-Otsubo, 2021, Cancer reports.

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

S. Miyano, Y. Shiraishi, K. Chiba, 2020, Communications biology.

Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms

S. Miyano, T. Naoe, Y. Shiraishi, 2016, Leukemia.

Frequent Activating Somatic Alterations in T-Cell Receptor / NF-κb Signaling in Adult T-Cell Leukemia/Lymphoma

S. Miyano, Y. Totoki, T. Shibata, 2015 .

Prevalence of pathogenic variants in cancer‐predisposing genes in second cancer after childhood solid cancers

K. Okamura, S. Ogawa, M. Takagi, 2023, Cancer medicine.

Radiation‐induced osteosarcoma in a patient with DICER1 syndrome

A. Sato-Otsubo, Mio Tanaka, K. Yamasaki, 2022, Pediatric blood & cancer.

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

S. Miyano, Y. Shiraishi, K. Chiba, 2020, Communications Biology.

mutations in adult T-cell leukemia / lymphoma

O. Nureki, S. Miyano, Y. Totoki, 2015 .

Landscape of Genetic Alterations in Adult T-Cell Leukemia/Lymphoma

H. Aburatani, O. Nureki, S. Miyano, 2014 .