P. Timmermans

J. H. Shaw, P. Timmermans, M. Thoolen, 1993, Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology.

Impairment by nifedipine of vasopressor responses to stimulation of postsynaptic alpha 2-adrenoreceptors in ganglion--blocked rabbits. Further evidence for the selective inhibition of postsynaptic alpha 2-adrenoreceptor-induced pressor responses by calcium antagonists.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1982, Journal of autonomic pharmacology.

Vascular smooth muscle contraction initiated by postsynaptic alpha 2-adrenoceptor activation is induced by an influx of extracellular calcium.

P. Timmermans, B. Wilffert, J. V. van Meel, 1981, European journal of pharmacology.

Differential effects of the calcium entry blocker D 600 on contractions of rat and guinea-pig aortas, elicited by various alpha-1 adrenoceptor agonists.

P. Timmermans, B. Wilffert, J. J. Beckeringh, 1984, The Journal of pharmacology and experimental therapeutics.

Alpha1- and alpha2-Adrenoceptor Mediated Vasoconstriction in the Forearm of Normotensive and Hypertensive Subjects

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1986 .

Angiotensin II receptor antagonists: an emerging new class of cardiovascular therapeutics.

P. Timmermans, 1999, Hypertension research : official journal of the Japanese Society of Hypertension.

Postsynaptic alpha 1- and alpha 2-adrenoceptors in human blood vessels: interactions with exogenous and endogenous catecholamines.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1987, European journal of clinical investigation.

Equal potency of nifedipine to inhibit α1-(dobutamine and BDF 6143) and α2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine

P. Timmermans, M. Thoolen, 1987 .

Postsynaptic α1‐ and α2‐adrenoceptors in human blood vessels: interactions with exogenous and endogenous catecholamines

P. Timmermans, P. Vermey, P. A. Zwieten, 1987 .

Arguments Against the Role of Receptor Reserve as a Determinant of the Sensitivity of α1‐Adrenoceptor‐Mediated Pressor Responses to Inhibition by Ca2+ Entry Blockers in the Pithed Rat

P. Timmermans, M. Thoolen, 1988 .

Comparison of inhibitory potency by nonpeptide angiotensin II receptor antagonists PD123177 and DuP 753 on proximal nephron and renal transport.

P. Timmermans, M. G. Cogan, F. Liu, 1991, The Journal of pharmacology and experimental therapeutics.

Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2).

P. Timmermans, A. Chiu, P. Wong, 1990, The Journal of pharmacology and experimental therapeutics.

Hypotensive activity of calcium entry blockers in rats. Relationship with depression of alpha 2-adrenoceptor-mediated vasopressor responses.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1983, European journal of pharmacology.

Differential inhibition of α2‐adrenoceptor‐mediated pressor responses by (+)‐ and (‐)‐verapamil in pithed rats

P. Timmermans, P. A. Zwieten, J. C. A. Meel, 1983, The Journal of pharmacy and pharmacology.

Nonpeptide Angiotensin II Receptor Antagonists: Studies With EXP9270 and DuP 753

P. Timmermans, W. Price, J. Duncia, 1990, Hypertension.

New perspectives in angiotensin system control.

P. Timmermans, A. Chiu, P. Wong, 1993, Journal of human hypertension.

Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. I. Central hypotensive and peripheral hypertensive activities.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1982, The Journal of pharmacology and experimental therapeutics.

Inhibitory effect of calcium antagonist drugs on vasoconstriction induced by vascular alpha 2-adrenoceptor stimulation.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1986, The American journal of cardiology.

Quantitative Comparative Studies on Peripheral and Central Bradycardia Induced by Imidazolidines

P. Timmermans, P. A. Zwieten, A. Jonge, 1982 .

Vascular aspects of calcium antagonists

P. Timmermans, P. A. Zwieten, J. C. A. Meel, 1981, Pharmaceutisch weekblad.

Involvement of α1- and α2-adrenoceptors in the vasoconstriction caused by ergometrine

P. Timmermans, P. A. Zwieten, H. Kalkman, 1982 .

Pharmacology of calcium entry blockers: interaction with vascular alpha-adrenoceptors.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1983, Hypertension.

Regional distribution of the two subtypes of angiotensin II receptor in rat brain using selective nonpeptide antagonists

P. Timmermans, A. Chiu, K. H. Leung, 1991, Neuroscience Letters.

Angiotensin Receptor Subtypes and their Pharmacology

C. Rosenfeld, P. Timmermans, R. Ardaillou, 1995 .

Differential effects of selective 287-1287-1287-1287-2287-2287-2agonists on intraocular pressure in the conscious rabbit

P. Timmermans, P. A. Zwieten, H. Innemee, 1982, Documenta Ophthalmologica.

Recent advances in the classification of α- adrenoceptors

P. Timmermans, P. A. Zwieten, 1980, Pharmaceutisch Weekblad.

Pharmacological characteristics of receptor-operated and potential-operated Ca2+ channels in rat aorta.

P. Timmermans, A. Chiu, D. E. McCall, 1986, European journal of pharmacology.

Enhancement of losartan (DuP 753)-induced angiotensin II receptor antagonism by PD123177 in rats.

P. Timmermans, D. Christ, P. Wong, 1992, European journal of pharmacology.

Angiotensin II-1 receptors mediate both vasoconstrictor and hypertrophic responses in rat aortic smooth muscle cells.

P. Timmermans, A. Chiu, W. Roscoe, 1991, Receptor.

The effect of selective α1- and α2-adrenoceptor stimulation on intraocular pressure in the conscious rabbit

P. Timmermans, P. A. Zwieten, H. Innemee, 1981, Naunyn-Schmiedeberg's Archives of Pharmacology.

Vasoconstriction mediated by postsynaptic α2-adrenoceptor stimulation

P. Timmermans, P. A. Zwieten, 1980, Naunyn-Schmiedeberg's Archives of Pharmacology.

Involvement of presynaptic alpha-adrenoceptors in the cardiovascular and sedative effects of FLA-136

P. Timmermans, P. A. Zwieten, E. Lam, 1979, Naunyn-Schmiedeberg's Archives of Pharmacology.

Characterization of alpha-adrenoceptors participating in the central hypotensive and sedative effects of clonidine using yohimbine, rauwolscine and corynanthine.

H. Y. Kwa, P. Timmermans, P. V. van Zwieten, 1981, European journal of pharmacology.

EVALUATION OF THE SELECTIVITY OF α-ADRENORECEPTOR BLOCKING DRUGS FOR POSTSYNAPTIC α1- AND α2-ADRENORECEPTORS IN A SIMPLE ANIMAL MODEL

P. Timmermans, P. Zwieten, J. C. A. Meel, 1980 .

Localization of angiotensin II receptor subtypes in the rabbit adrenal and kidney

P. Timmermans, S. Diamond, W. Herblin, 1991, Peptides.

Effects of the nonpeptide angiotensin II receptor antagonist DuP 753 on blood pressure and renal functions in spontaneously hypertensive PH dogs.

P. Timmermans, P. Wong, M. Thoolen, 1991, American journal of hypertension.

Biotechnology and the pharmaceutical industry. New cardiovascular drugs.

P. Timmermans, M. Dibner, 1986, Hypertension.

Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.

P. Timmermans, W. Price, J. Duncia, 1990, Hypertension.

Non-peptide angiotensin II receptor antagonists. II. Pharmacology of S-8308.

P. Timmermans, W. Price, D. Carini, 1988, European journal of pharmacology.

Nonpeptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-(2-chlorobenzyl)imidazole-5-acetic acid, sodium salt (S-8307).

P. Timmermans, W. Price, D. Carini, 1988, The Journal of pharmacology and experimental therapeutics.

Peroxidase secretion from rat lacrimal gland cells in vitro: II. The role of calcium in stimulus-secretion coupling.

P. Timmermans, N. V. van Haeringen, P. V. van Zwieten, 1983, Experimental eye research.

Receptor Antagonists: an Emerging of Cardiovascular Therapeutics

P. Timmermans, 2006 .

alpha 1- and alpha 2-adrenoceptor stimulation in the isolated perfused hindquarters of the rat: an in vitro model.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1983, Journal of cardiovascular pharmacology.

Angiotensin II monoclonal antibody: blood pressure effects in normotensive and spontaneously hypertensive rats.

P. Timmermans, T. Reilly, P. Wong, 1990, European journal of pharmacology.

Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo.

P. Timmermans, D. W. Watson, T. Reilly, 1989, Biochemical and biophysical research communications.

DuP 753 is a potent nonpeptide antagonist of angiotensin II receptors in isolated perfused rat kidney and cultured renal cells.

P. Timmermans, B. Fontoura, D. Nussenzveig, 1991, American journal of hypertension.

In vitro pharmacology of DuP 753.

P. Timmermans, W. Price, J. Duncia, 1991, American journal of hypertension.

Effects of DuP 753 on proximal nephron and renal transport.

P. Timmermans, M. G. Cogan, F. Liu, 1991, American journal of hypertension.

Nonpeptide angiotensin II receptor antagonists. IX. Antihypertensive activity in rats of DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Morphine suppresses the blood pressure responses to clonidine withdrawal in the spontaneously hypertensive rat.

P. Timmermans, P. V. van Zwieten, M. Thoolen, 1981, European journal of pharmacology.

Pharmacology of nonpeptide angiotensin II receptor antagonists.

P. Timmermans, A. Chiu, P. Wong, 1992, Annual review of pharmacology and toxicology.

In Vivo Characterization of a New Synthetic Thrombin Inhibitor

P. Timmermans, R. Knabb, T. Reilly, 1992, Thrombosis and Haemostasis.

Defining Angiotensin Receptor Subtypes

P. Timmermans, A. Chiu, Ronald D. Smith, 1994 .

Immunological reactivity of angiotensin II receptor antagonists: possible implications for receptor binding sites.

P. Timmermans, P. Verroust, T. Reilly, 1993, European journal of pharmacology.

Angiotensin II receptor antagonists and receptor subtypes

P. Timmermans, J. Duncia, A. Chiu, 1992, Trends in Endocrinology & Metabolism.

Modulation of Noradrenaline Release by Peripheral Presynaptic α2‐Adrenoceptors in Humans

P. Timmermans, P. V. van Zwieten, P. Vermey, 1987 .

Effects of exogenous adrenaline and noradrenaline on vascular postsynaptic alpha 1- and alpha 2-adrenoceptors in man.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1984, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

Modulation of noradrenaline release by peripheral presynaptic alpha 2-adrenoceptors in humans.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1987, Journal of cardiovascular pharmacology.

Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities.

H. Y. Kwa, P. Timmermans, P. V. van Zwieten, 1980, Archives internationales de pharmacodynamie et de therapie.

Alpha-adrenoceptor control of peroxidase secretion from rat lacrimal gland cells in vitro.

P. Timmermans, N. V. van Haeringen, P. V. van Zwieten, 1982, Experimental eye research.

Identical antagonist selectivity of central and peripheral alpha 1-adrenoceptors.

H. Y. Kwa, P. Timmermans, P. V. van Zwieten, 1981, Molecular pharmacology.

Angiotensin II receptor subtypes: selective antagonists and functional correlates.

R. D. Smith, P. Timmermans, R. Smith, 1994, European heart journal.

Characterization of the antihypertensive properties of ketanserin (R 41 468) in rats.

P. Timmermans, P. V. van Zwieten, H. Kalkman, 1982, The Journal of pharmacology and experimental therapeutics.

Angiotensin II receptors and functional correlates.

P. Timmermans, A. Chiu, P. Wong, 1992, American journal of hypertension.

Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.

P. Timmermans, J. Duncia, J. Santella, 1994 .

The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist

P. Timmermans, W. Price, J. Duncia, 1992, Medicinal research reviews.

Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.

K Prendergast, W. Greenlee, P. Timmermans, 1996, Journal of medicinal chemistry.

DuP 532: a second generation of nonpeptide angiotensin II receptor antagonists.

P. Timmermans, W. Price, J. Duncia, 1991, Biochemical and biophysical research communications.

Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent.

P. Timmermans, W. Price, J. Duncia, 1990, The Journal of pharmacology and experimental therapeutics.

Centrally acting hypotensive drugs

P. Timmermans, 1984 .

Correlations between central hypotensive and peripheral hypertensive effects of structurally dissimilar alpha-adrenoceptor agonists.

P. Timmermans, P. V. van Zwieten, 1981, Life sciences.

The hypotensive activity and side effects of methyldopa, clonidine, and guanfacine.

P. Timmermans, P. V. van Zwieten, M. Thoolen, 1984, Hypertension.

Antihypertensive Activity of 2[(2-Hydroxyphenyl) amino] -4(3H)-quinazolinone

M. Hussain, P. Timmermans, W. Price, 1988, Pharmaceutical Research.

Nonpeptide angiotensin II receptor antagonists. III. Structure-function studies.

P. Timmermans, W. Price, J. Duncia, 1989, The Journal of pharmacology and experimental therapeutics.

Furo- and thieno[2,3-b]pyrazines. Part 2. Chemical properties of 2-substituted derivatives

P. Timmermans, A. D. Gen, C. G. Kruse, 1978 .

Pyrazoles XI. The synthesis of 1,1′-dimethylbipyrazolyls

P. Timmermans, C. L. Habraken, A. Uijttewaal, 1972 .

The preparation of (perfluoroalkyl)imidazoles as nonpeptide angiotensin II receptor antagonists

P. Timmermans, R. Wexler, D. Carini, 1993 .

Angiotensin II receptors and angiotensin II receptor antagonists.

P. Timmermans, R. Wexler, D. Carini, 1993, Pharmacological reviews.

Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Kalyan C. Tirupula, L. Hunyady, P. Timmermans, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Neuropharmacological profile of a new series of dopamine agonists: N-n-propyl-hexahydronaphthoxazines.

P. Timmermans, J. D. de Vries, D. Dijkstra, 1986, European journal of pharmacology.

Interaction between beta 2-adrenoceptor-mediated vasodilation and alpha 2-adrenoceptor-mediated vasoconstriction in the pithed normotensive rat.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983, Journal of Cardiovascular Pharmacology.

Nonpeptide angiotensin II receptor antagonists: N-[(benzyloxy)benzyl]imidazoles and related compounds as potent antihypertensives.

P. Timmermans, W. Price, J. Duncia, 1990, Journal of medicinal chemistry.

The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives.

P. Timmermans, W. Price, J. Duncia, 1990, Journal of medicinal chemistry.

Interaction Between β2‐Adrenoceptor‐Mediated Vasodilation and α1‐Adrenoceptor‐Mediated Vasoconstriction in the Pithed Normotensive Rat

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983 .

Heterogeneity of the interaction between α1- and α2-adrenoceptor agonists with their respective receptors in the vascular system of the pithed rat

P. Timmermans, B. Wilffert, M. Thoolen, 1984 .

Interaction between the calcium entry blocker nifedipine with the alpha 1-adrenoreceptor-mediated increase in diastolic pressure elicited by catecholamines.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1984, Journal of autonomic pharmacology.

Sgd 101/75 is distinguished from other selective alpha 1-adrenoceptor agonists by the inhibition of its pressor responses by calcium entry blockade and vasodilatation in pithed rats and cats.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983, European journal of pharmacology.

Role of ganglionic M-1 and M-2 receptors in the neuronal control of the cardiovascular system of the normotensive rat as determined with pilocarpine.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983, European journal of pharmacology.

The clonidine withdrawal syndrome. Its reproduction and evaluation in laboratory animal models.

P. Timmermans, P. V. van Zwieten, M. Thoolen, 1981, General pharmacology.

Withdrawal syndrome after continuous infusion of clonidine in the normotensive rat

P. Timmermans, M. Thoolen, P. Zwieten, 1981, The Journal of pharmacy and pharmacology.

α2 ADRENOCEPTORS: CLASSIFICATION, LOCALIZATION, MECHANISMS AND TARGETS FOR DRUGS

P. Timmermans, P. A. Zwieten, 1983 .

2‐(Arylimino)imidazolidines; synthesis and hypotensive activity

P. Timmermans, P. Zwieten, W. Speckamp, 2010 .

A lipophilic, selective α1 -adrenoceptor agonist: 2-(2-chloro-5-trifluoromethylphenylimino) imidazolidine (St 587)

P. Timmermans, P. A. Zwieten, A. Jonge, 1981 .

Quantitative structure-activity relationships in centrally acting imidazolidines structurally related to clonidine.

P. Timmermans, P. V. van Zwieten, P B Timmermans, 1977, Journal of medicinal chemistry.

Peroxidase secretion from rat lacrimal gland cells in vitro. I. Alpha-adrenergic stimulation in the absence of alpha-adrenoceptors.

P. Timmermans, N. V. van Haeringen, P. V. van Zwieten, 1983, Experimental eye research.

Angiotensin II receptor antagonist markedly reduces mortality in salt-loaded Dahl S rats.

J. Laragh, P. Timmermans, M. Camargo, 1991, American journal of hypertension.

Captopril impairs the vascular smooth muscle contraction mediated by postsynaptic alpha 2-adrenoceptors in the pithed rat.

P. Timmermans, B. Wilffert, J. V. van Meel, 1981, European journal of pharmacology.

Correlation between the affinity for [3H]mianserin-labelled receptors in brain and antagonism of the serotonin pressor response in pithed rats.

P. Timmermans, H. Batink, P. V. van Zwieten, 1983, Biochemical pharmacology.

Differential mode of antagonism of 5‐hydroxytryptamine‐induced pressor effects by (+)‐ and (‐)‐mianserin in pithed rats

P. Timmermans, H. Kalkman, P. Zwieten, 1983, The Journal of pharmacy and pharmacology.

Hypotensive activity of serotonin receptor agonists in rats is related to their affinity for 5-HT1 receptors.

H. Boddeke, P. Timmermans, P. V. van Zwieten, 1983, European journal of pharmacology.

Lack of effect of D600 on alpha 1-adrenoceptor-mediated contractions of rat isolated anococcygeus muscle.

P. Timmermans, J. J. Beckeringh, E. Vila, 1984, European journal of pharmacology.

Interactions between the putative calcium entry promotor Bay k 8644 and pressor responses produced by α-1 and α2-adrenocepter agonists in the pithed normotensive rat

P. Timmermans, B. Wilffert, M. Thoolen, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

Differential effect of calcium entry blockers on α1-adrenoceptor-mediated vasoconstriction in vivo

P. Timmermans, B. Wilffert, M. Thoolen, 1983, Naunyn-Schmiedeberg's Archives of Pharmacology.

Hypotensive activity of serotonin antagonists; correlation with alpha 1-adrenoceptor and serotonin receptor blockade.

P. Timmermans, H. Batink, P. V. van Zwieten, 1983, Life sciences.

Angiotensin II receptor subtypes.

R D Smith, P. Timmermans, P C Wong, 1992, American journal of hypertension.

Effects of the irreversible α-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting α1- and α2-adrenoceptor mediated vasoconstriction in pithed rats

P. Timmermans, B. Wilffert, M. Thoolen, 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.

Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. III. Comparison of central and peripheral alpha-1 and alpha-2 adrenoceptors.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1983, The Journal of pharmacology and experimental therapeutics.

Dissociation constants of clonidine and structurally related imidazolidines.

P. Timmermans, P. V. van Zwieten, 1978, Arzneimittel-Forschung.

Quantum chemical studies on clonidine and related derivatives.

P. Timmermans, P. V. van Zwieten, J. Mulder, 1977, Arzneimittel-Forschung.

Clonidine base: evidence for conjugation of both ring systems.

P. Timmermans, P. V. van Zwieten, J. Mulder, 1975, Molecular pharmacology.

Ca++ utilization in the constriction of rat aorta to full and partial alpha-1 adrenoceptor agonists.

P. Timmermans, A. Chiu, M. Thoolen, 1986, The Journal of pharmacology and experimental therapeutics.

calcium Influx-dependent and -independent α1-adrenoceptor-mediated Processes of Vasoconstriction In Vivo Do Not Operate via Different α1-adrenoceptor Subtypes

P. Timmermans, B. Wilffert, M. Thoolen, 1984 .

Calcium antagonists and alpha 2-adrenoceptors: possible role of extracellular calcium ions in alpha 2-adrenoceptor-mediated vasoconstriction.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1982, Journal of cardiovascular pharmacology.

Guanfacine and clonidine: antihypertensive and withdrawal characteristics after continuous infusion and its interruption in the spontaneously hypertensive and normotensive rat

P. Timmermans, M. Thoolen, P. A. Zwieten, 1982, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cardiovascular effects of withdrawal of some centrally acting antihypertensive drugs in the rat

P. Timmermans, M. Thoolen, P. Zwieten, 1983 .

The contractions induced in rat and guinea-pig aortic strips by the alpha 2-adrenoceptor selective agonists B-HT 920 and UK 14,304 are mediated by alpha 1-adrenoceptors.

P. Timmermans, B. Wilffert, J. J. Beckeringh, 1984, European journal of pharmacology.

Selective stimulation of vascular postjunctional alpha-adrenoreceptors by (-)-amidephrine in rats and cats.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983, Journal of autonomic pharmacology.

Effect of salbutamol and the PDE-inhibitor RA 642 on the clonidine withdrawal syndrome in rats.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1984, Journal of autonomic pharmacology.

Balanced angiotensin II receptor antagonists. II.1,2 4-aminomethyl- and acylaminomethylimidazoles

P. Timmermans, R. Olson, R. Wexler, 1994 .

Hypotensive Activity of Tetrandrine in Rats

P. Timmermans, P. A. Zwieten, M. Thoolen, 1983 .

Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. II. Central and peripheral bradycardic activities.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1982, The Journal of pharmacology and experimental therapeutics.

Cardiovascular effects and interaction with adrenoceptors of urapidil.

P. Timmermans, B. Wilffert, J. J. Beckeringh, 1985, Archives internationales de pharmacodynamie et de therapie.

Accumulation of drugs by resting or beating cardiac tissue.

P. Timmermans, H. Lüllmann, A. Ziegler, 1979, European journal of pharmacology.

Angiotensin II Receptor Antagonists From Discovery to Antihypertensive Drugs

P. Timmermans, W. Price, J. Duncia, 1991, Hypertension.

A novel angiotensin II binding site in murine tissues.

P. Timmermans, R. Gibson, F. Barbera, 1998, Life sciences.

Effect of Blocking Angiotensin II Receptor Subtype on Rat Sympathetic Nerve Function

P. Timmermans, P. Wong, R. Bernard, 1992, Hypertension.

Alpha-adrenoceptor stimulation and calcium movements.

P. Timmermans, P. V. van Zwieten, 1987, Blood vessels.

Postsynaptic alpha 1- and alpha 2-adrenoceptor blocking properties of (dihydro)quinidine and (dihydro)quinine.

P. Timmermans, J. V. van Meel, H. Batink, 1983, Arzneimittel-Forschung.

Dual inhibitory effects of azapropazone on both neutrophil migration and function: relation to cardiovascular protection

S. Mousa, P. Timmermans, P. Turlapaty, 1989 .

Pharmacology of Azapropazone: Potential Utility in the Treatment of Ischemia/Reperfusion Injury

S. Mousa, P. Timmermans, K. Rainsford, 1992 .

Myocardial Cytoprotective Efficacy of Azapropazone in a Canine Heart Model of Regional Ischemia and Reperfusion

S. Mousa, P. Timmermans, J. Cooney, 1989, Journal of Cardiovascular Pharmacology.

Effect of calcium entry blockers on blood pressure and vasoconstrictor responses to alpha-1 adrenoceptor stimulation in conscious spontaneously hypertensive rats

P. Timmermans, A. Chiu, M. Thoolen, 1987, Cardiovascular Drugs and Therapy.

Furo‐ and thieno[2,3‐b]pyrazines. Part 1. Synthesis of 2‐substituted derivatives

P. Timmermans, A. D. Gen, C. Kruse, 2010 .

Effect of age on the prejunctional α-adrenoceptor-mediated feedback in the heart of spontaneously hypertensive rats and normotensive Wistar Kyoto rats

P. Timmermans, P. A. Zwieten, P. N. Santing, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effect of age on the prejunctional alpha-adrenoceptor-mediated feedback in the heart of spontaneously hypertensive rats and normotensive Wistar Kyoto rats. Evidence for a physiological role of prejunctional alpha 2-adrenoceptors.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1983, Naunyn-Schmiedeberg's archives of pharmacology.

Proximal nephron and renal effects of DuP 753, a nonpeptide angiotensin II receptor antagonist.

P. Timmermans, M. G. Cogan, F. Liu, 1990, Kidney international.

Hemodynamic characterization of pinacidil in rats. Comparison with hydralazine.

P. Timmermans, B. Wilffert, J. V. van Meel, 1983, Pharmacology.

The role of central α-adrenoceptors in the mode of action of hypotensive drugs

P. Timmermans, P. A. Zwieten, 1979 .

Participation of cardiac presynaptic α1-Adrenoceptors in the bradycardiac effects of clonidine and analogues

P. Timmermans, P. A. Zwieten, A. Jonge, 1981, Naunyn-Schmiedeberg's Archives of Pharmacology.

FUNCTIONAL ROLE OF CARDIAC PRESYNAPTIC α2‐ADRENORECEPTORS IN THE BRADYCARDIA OF α‐ADRENORECEPTOR AGONISTS IN PENTOBARBITONE‐ AND URETHANE‐ANAESTHETIZED NORMOTENSIVE RATS

P. Timmermans, P. A. Zwieten, P. N. Santing, 1982 .

A monoclonal anti-idiotypic antibody which mimics angiotensin II in inducing a population of anti-hormone antibodies.

P. Timmermans, T. Mitchell, T. Reilly, 1987, Hybridoma.

Characterization of biochemical responses of angiotensin II (AT2) binding sites in the rat pheochromocytoma PC12W cells.

P. Timmermans, A. Chiu, R. Smith, 1992, European journal of pharmacology.

Human angiotensin receptor subtypes.

P. Timmermans, R. Smith, 1994, Current opinion in nephrology and hypertension.

DuP 753 increases survival in spontaneously hypertensive stroke-prone rats fed a high sodium diet.

J. Laragh, P. Timmermans, G. James, 1991, American journal of hypertension.

Quantitative description of α2-adrenergic potency in terms of receptor affinity and intrinsic activity

P. Timmermans, P. A. Zwieten, A. Jonge, 1984 .

[3H]DUP 753, a highly potent and specific radioligand for the angiotensin II-1 receptor subtype.

P. Timmermans, P. Aldrich, A. Chiu, 1990, Biochemical and biophysical research communications.

Central and Peripheral a-Adrenoceptors:

P. Timmermans, B. Wilffert, P. A. Zwieten, 1982 .

Central and peripheral alpha-adrenoceptors.

P. Timmermans, B. Wilffert, J. V. van Meel, 1982, Journal of cardiovascular pharmacology.

The preclinical basis of the therapeutic evaluation of losartan

P. Timmermans, A. Chiu, P. Wong, 1995, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

Further studies on the selectivity of DuP 753, a nonpeptide angiotensin II receptor antagonist.

P. Timmermans, P. Wong, S. Tam, 1991, European journal of pharmacology.

Dose-response relationships following oral administration of DuP 753 to normal humans.

Y. Christen, P. Timmermans, B. Waeber, 1991, American journal of hypertension.

In vivo pharmacology of DuP 753.

P. Timmermans, W. Price, J. Duncia, 1991, American journal of hypertension.

Angiotensin II receptor antagonists in heart failure: Rationale and design of the evaluation of losartan in the elderly (ELITE) trial

B. Pitt, P. Timmermans, P. Chang, 1995, Cardiovascular Drugs and Therapy.

Rationale, background, and design of the randomized angiotensin receptor antagonist--angiotensin-converting enzyme inhibitor study (RAAS).

P. Timmermans, W. Grossman, B. Pitt, 1996, The American journal of cardiology.

M-7 lowers rabbit intraocular pressure.

P. Timmermans, P. Hoyng, P. V. van Zwieten, 1985, Ophthalmic research.

Effects of urapidil on blood pressure and adrenoceptors in various animal models.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1984, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

Cardiovascular alpha 2-receptors.

P. Timmermans, P. V. van Zwieten, 1983, Journal of Molecular and Cellular Cardiology.

Invariable susceptibility to blockade by nifedipine of vasoconstriction to various α2‐adrenoceptor agonists in pithed rats

P. Timmermans, B. Wilffert, M. Thoolen, 1984, The Journal of pharmacy and pharmacology.

Differential selectivities of RU 24969 and 8-OH-DPAT for the purported 5-HT1A and 5-HT1B binding sites. Correlation between 5-HT1A affinity and hypotensive activity.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1985, European journal of pharmacology.

Non-peptide angiotensin II receptor antagonist and angiotensin-convering enzyme inhibitor: effect on a renin-induced deficit of a passive avoidance response in rats

P. Timmermans, A. Chiu, V. Denoble, 1991, Brain Research.

Calcium handling in vasoconstriction to stimulation of alpha 1- and alpha 2-adrenoceptors.

P. Timmermans, A. Chiu, M. Thoolen, 1987, Canadian Journal of Physiology and Pharmacology.

Heterogenous effects of Ca2+ entry blockers on biphasic constriction of the rabbit ear artery

P. Timmermans, P. Wong, C. J. Keirans, 1986 .

The interaction between prazosin and clonidine.

P. Timmermans, P. V. van Zwieten, E. Lam, 1978, Clinical science and molecular medicine. Supplement.

Calcium entry blockers: a review with an attempt at classification.

P. Timmermans, P. V. van Zwieten, 1983, European heart journal.

Receptor Subtypes Involved in the Action of Calcium Entry Blockers

P. Timmermans, P. A. Zwieten, 1988, Annals of the New York Academy of Sciences.

Effects of nifedipine on phasic and tonic vasoconstrictor responses to Sgd 101/75 in the isolated perfused rabbit ear artery.

P. Timmermans, P. Wong, S. Hart, 1994, European journal of pharmacology.

Ca++ utilization in the constriction of rat aorta to stimulation of protein kinase C by phorbol dibutyrate.

P. Timmermans, J. Bozarth, M. Forsythe, 1987, The Journal of pharmacology and experimental therapeutics.

Differential role of M-1 and M-2 receptors in sympathetic ganglia of the pithed normotensive rat in alpha adrenoceptor-mediated vasoconstriction.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1983, The Journal of pharmacology and experimental therapeutics.

Relationship between phosphatidylinositol turnover and Ca++ mobilization induced by alpha-1 adrenoceptor stimulation in the rat aorta.

P. Timmermans, J. Bozarth, A. Chiu, 1987, The Journal of pharmacology and experimental therapeutics.

Sensitivity of alpha-1 adrenoceptor-mediated pressor responses to inhibition by Ca++ entry blockers in the pithed rat: arguments against the role of receptor reserve.

P. Timmermans, J. J. Beckeringh, P. V. van Zwieten, 1987, The Journal of pharmacology and experimental therapeutics.

Calcium utilization in the vasoconstriction to enantiomers of SK&F 89748-A.

P. Timmermans, B. Wilffert, J. J. Beckeringh, 1985, Journal of Pharmacology and Experimental Therapeutics.

Inhibitors of the angiotensin I converting enzyme as antihypertensive drugs

P. Timmermans, P. A. Zwieten, A. Jonge, 1983, Pharmaceutisch Weekblad.

Differential prejunctional effect of captopril and saralasin on neurogenic vasoconstriction in pithed normotensive rats.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1984, Life sciences.

Effect of captopril on sympathetic neurotransmission in pithed normotensive rats.

P. Timmermans, B. Wilffert, P. van Brummelen, 1983, European journal of pharmacology.

Hypotensive and α‐adrenergic activities of 2‐(2,3,6‐trichlorophenylimino) and 2‐(2,3‐dichloro‐6‐methylphenylimino) imidazolidine, two potent derivatives of clonidine

P. Timmermans, P. Zwieten, A. Jonge, 1983, British Journal of Pharmacology.

Correlation between the inhibitory activities of calcium entry blockers on vascular smooth muscle constriction in vitro after K+-depolarisation and in vivo afterα2-adrenoceptor stimulation

P. Timmermans, R. Towart, P. A. Zwieten, 1983, Naunyn-Schmiedeberg's Archives of Pharmacology.

Functional interaction between calcium antagonists and the vasoconstriction induced by the stimulation of postsynaptic alpha 2-adrenoceptors.

P. Timmermans, J. V. van Meel, P. V. van Zwieten, 1983, Circulation Research.

Sgd 101/75: cardiovascular effects in various animal preparations; interactions with vascular postjunctional α1‐ and α2‐adrenoceptors

P. Timmermans, M. Thoolen, M. Mathy, 1984 .

Lack of relationship between intrinsic activity and susceptibility of pressor responses to blockade by nifedipine among the α2 agonists B-HT 920 and B-HT 958

P. Timmermans, B. Wilffert, H. Batink, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

The influence of α1‐ and α2‐adrenoceptor agonists on cardiac output in rats and cats

P. Timmermans, M. Thoolen, P. A. Zwieten, 1984 .

Hemodynamic Profiles of Methoxamine and B‐HT 933 in Spinalized Ganglion‐Blocked Dogs

P. Timmermans, P. Zandberg, P. V. van Zwieten, 1984, Journal of cardiovascular pharmacology.

The influence of alpha 1- and alpha 2-adrenoceptor agonists on cardiac output in rats and cats.

P. Timmermans, P. V. van Zwieten, M. Thoolen, 1984, The Journal of pharmacy and pharmacology.

α1/α2-Adrenoceptor agonist selectivity of mono- and dihydroxy-2-N,N-di-n-propylaminotetralins

P. Timmermans, B. Wilffert, M. Mathy, 1984 .

Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.

J. Hieble, P. Timmermans, B. Wilffert, 1984, European journal of pharmacology.

INTERACTION OF CLONIDINE, ITS METHYLENE‐BRIDGED ANALOG, St 1913, AND THE BENZYLIC HYDROXYL‐SUBSTITUTED DERIVATIVE, St 1965, WITH α1‐ AND α2‐ADRENORECEPTORS

R. Ruffolo, P. Timmermans, P. Zwieten, 1983 .

Inhibitory dopamine receptors on sympathetic neurons innervating the cardiovascular system of the pithed rat

P. Timmermans, B. Wilffert, M. Thoolen, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

Centrally mediated hypotensive activity of B-HT 933 upon infusion via the cat's vertebral artery.

P. Timmermans, P. V. van Zwieten, 1980, Pharmacology.

Central hypotensive action of bridge analogues of clonidine.

P. Timmermans, P. V. van Zwieten, J. Mackay, 1979, Pharmacology.

Mini-review. The postsynaptic alpha 2-adrenoreceptor.

P. Timmermans, P. V. van Zwieten, 1981, Journal of autonomic pharmacology.

Interference of enantiomers of lofexidine with alpha-adrenoceptors.

P. Timmermans, B. Wilffert, H. Batink, 1985, Archives internationales de pharmacodynamie et de therapie.

Binding of (+/-)-3H-lofexidine to alpha-adrenoceptors in membranes from rat brain.

P. Timmermans, P. V. van Zwieten, E. Graf, 1983, Archives internationales de pharmacodynamie et de therapie.

Imidazolinones as nonpeptide angiotensin II receptor antagonists

P. Timmermans, R. Wexler, A. Chiu, 1994 .

Brain levels and acute antihypertensive activity of β-Blockers

P. Timmermans, P. A. Zwieten, 2004, European Journal of Clinical Pharmacology.

Comparison Between the Acute Hemodynamic Effects and Brain Penetration of Atenolol and Metoprolol

P. Timmermans, P. V. van Zwieten, P. A. V. Zwieten, 1979, Journal of cardiovascular pharmacology.

A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors.

R. Ruffolo, P. Timmermans, P. V. van Zwieten, 1984, The Journal of pharmacology and experimental therapeutics.

Two clonidine-like compounds with substituents at the 2-, 3-, and 6-position of the phenyl ring possessing pronounced hypotensive potencies.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1982, Journal of medicinal chemistry.

Discrimination between peripheral and central alpha-adrenergic effects using meta-substituted imidazolidines.

P. Timmermans, P. V. van Zwieten, A. de Jonge, 1981, European journal of pharmacology.

Central hypotensive and antihypertensive activities of imidazolidines, structurally related to clonidine.

P. Timmermans, P. V. van Zwieten, 1977, Archives internationales de pharmacodynamie et de therapie.

Hypotensive and bradycardic activities of clonidine and related imidazolidines; structure-activity relationship.

P. Timmermans, P. V. van Zwieten, 1977, Archives internationales de pharmacodynamie et de therapie.

Rationale for the chemical development of angiotensin II receptor antagonists.

P. Timmermans, J. Duncia, R. Wexler, 1992, American journal of hypertension.

Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1986, Archives internationales de pharmacodynamie et de therapie.

Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.

P. Timmermans, B. Wilffert, H. Batink, 1984, Journal of medicinal chemistry.

Effect of adrenalectomy and demedullation of the adrenals on vasopressor responses to stimulation of postjunctional alpha 2-adrenoceptors.

P. Timmermans, B. Wilffert, J. V. van Meel, 1983, European journal of pharmacology.

The hydroxy‐hexanydronaphthoxazines: a new group of very potent and selective dopamine agonists

P. Timmermans, D. Dijkstra, J. Vries, 1984, The Journal of pharmacy and pharmacology.

Nonpeptide angiotensin II receptor antagonists: insurmountable angiotensin II antagonism of EXP3892 is reversed by the surmountable antagonist DuP 753.

P. Timmermans, P. Wong, 1991, The Journal of pharmacology and experimental therapeutics.

Inhibition of the thrombin-platelet reactions by DuP 714.

S. Mousa, P. Timmermans, J. Bozarth, 1991, Biochemical and biophysical research communications.

Indications for vascular alpha- and beta-2 adrenoceptors in synapses of the muscarinic pathway in the pithed normotensive rat.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1982, The Journal of pharmacology and experimental therapeutics.

Chapter 6. CNS Autoreceptors as Targets for Drug Design

P. Timmermans, 1984 .

Effect of chronic elevation of plasma calcium concentration by PTH or vitamin D3 on blood pressure and hypotensive activity of nifedipine in rats

P. Timmermans, B. Wilffert, M. Thoolen, 1984, Pflügers Archiv.

Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.

P. Timmermans, H. Lüllmann, A. Ziegler, 1980, Journal of medicinal chemistry.

Tissue plasminogen activator-induced secretion of type-1 plasminogen activator inhibitor in cultured human fibroblasts.

P. Timmermans, T. Reilly, G. Greenplate, 1989, Thrombosis research.

Cardiovascular new drug discovery of the future: Molecules, genes, and machines

P. Timmermans, Ronald D. Smith, 1997 .

Receptor Subtypes Involved in the Action of Calcium Antagonists

P. Timmermans, P. V. van Zwieten, P. van Heiningen, 1987, Journal of hypertension. Supplement : official journal of the International Society of Hypertension.

The diversified pharmacology of angiotensin II-receptor blockade.

P. Timmermans, R. Smith, 1996, Blood pressure. Supplement.

Discovery of losartan, the first angiotensin II receptor antagonist.

P. Timmermans, J. Duncia, R. Wexler, 1995, Journal of human hypertension.

Monoclonal antibodies to the nonpeptide angiotensin II receptor antagonist, losartan.

P. Timmermans, S. Pierce, T. Reilly, 1992, European journal of pharmacology.

Vascular alpha-adrenoceptors in man: interactions with adrenaline and noradrenaline.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1985, Clinical science.

Effects of (+)- and (−)-Mianserin on α-adrenoceptors and tyramine-induced tachycardia in rats

P. Timmermans, P. A. Zwieten, H. Kalkman, 1983 .

Effects of (+)- and (-)-mianserin on alpha-adrenoceptors and tyramine-induced tachycardia in rats.

P. Timmermans, P. V. van Zwieten, H. Kalkman, 1983, European journal of pharmacology.

Historical development of losartan (DuP 753) and angiotensin II receptor subtypes.

P. Timmermans, P. Wong, 1996, Blood pressure. Supplement.

Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.

M. Lindstrom, N. Walker, P. Timmermans, 2013, Bioorganic & medicinal chemistry.

Differences between exogenous and endogenous noradrenaline in the effects on vascular post-synaptic alpha 1- and alpha 2-adrenoceptors in man.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1985, Journal of Hypertension - Supplement.

Alpha 1-and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of normotensive and hypertensive subjects.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1986, Journal of Cardiovascular Pharmacology.

Characterization of Angiotensin II Receptors

P. Timmermans, Ronald D. Smith, D. E. McCall, 1998 .

Effect of Angiotensin II Antagonism on Canine Renal Sympathetic Nerve Function

P. Timmermans, P. Wong, Scott D. Hart, 1991, Hypertension.

Pharmacology and pharmacokinetics of a novel nonpeptide angiotensin II receptor antagonist--DMP 811.

P. Timmermans, W. Price, R. Wexler, 1995, Clinical and experimental hypertension.

Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities

P. Timmermans, R. Olson, R. Wexler, 1994 .

EXP597, a nonpeptide angiotensin II receptor antagonist with high affinities for the angiotensin AT1 and AT2 receptor subtypes.

P. Timmermans, J. Duncia, J. Santella, 1994, European journal of pharmacology.

Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist.

P. Timmermans, R. Wexler, D. Carini, 1991, The Journal of pharmacology and experimental therapeutics.

Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.

P. Timmermans, W. Price, J. Duncia, 1990, Blood vessels.

Differential pharmacological properties of beta-adrenoceptor blocking drugs.

P. Timmermans, P. V. van Zwieten, 1983, Journal of cardiovascular pharmacology.

Angiotensin II receptor subtypes and their selective nonpeptide ligands.

P. Timmermans, J. Duncia, A. Chiu, 1990, Receptor.

Pharmacology and characterization of central alpha-adrenoceptors involved in the effect of centrally acting antihypertensive drugs.

P. Timmermans, P. V. van Zwieten, 1983, Chest.

Lipophilicity and brain disposition of clonidine and structurally related imidazolidines

P. Timmermans, P. A. Zwieten, P. B. M. W. M. Timmermans, 1977, Naunyn-Schmiedeberg's Archives of Pharmacology.

Identification of angiotensin II receptor subtypes.

P. Timmermans, L. Pease, J. Duncia, 1989, Biochemical and biophysical research communications.

Precipitation by Yohimbine of the Withdrawal Syndromes of Clonidine, Guanfacine, and Methyldopa in the Spontaneously Hypertensive Rat

P. Timmermans, P. V. van Zwieten, J. Hendriks, 1983, Journal of cardiovascular pharmacology.

Differential Pharmacological Properties of β‐Adrenoceptor Blocking Drugs

P. Timmermans, P. V. van Zwieten, 1983 .

Effects of PN 200-110, a new calcium antagonist, on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction elicited by selective alpha-adrenoceptor agonists and catecholamines in the pithed rat.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1985, Archives internationales de pharmacodynamie et de therapie.

Discontinuation syndrome after continuous infusion of clonidine in the spontaneously hypertensive rat.

P. Timmermans, P. V. van Zwieten, M. Thoolen, 1981, Life sciences.

Analysis of the displaceable binding of the hypotensive drug R 28935 in rat brain.

P. Timmermans, H. Batink, P. V. van Zwieten, 1982, Biochemical pharmacology.

Specific binding of threo 1-{1-[2-(1,4-benzo-dioxane-2-yl)-2-hydroxyethyl] 4-piperidyl}-2-benzimidazolinone (R 29814), to rat brain membranes

P. Timmermans, H. Batink, P. A. Zwieten, 1982, Neuropharmacology.

o-Adrenoceptor binding in guinea-pig lung using [3H]-prazosin

C. Dollery, P. Timmermans, C. Hamilton, 2007 .

Hypotensive properties of benzodioxane derivatives structurally related to R 28935. Comparison of activity with some receptor affinities.

P. Timmermans, H. Batink, P. V. van Zwieten, 1982, Archives internationales de pharmacodynamie et de therapie.

Heterogeneity of vascular alpha-adrenoceptors in man.

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1987, Canadian journal of physiology and pharmacology.

Inhibitory effect of alpha-1 adrenoceptor stimulation on cardiac sympathetic neurotransmission in pithed normotensive rats.

P. Timmermans, B. Wilffert, P. V. van Zwieten, 1986, Journal of Pharmacology and Experimental Therapeutics.

EXP 6803, A Nonpeptide Angiotensin II Receptor Antagonist

P. Timmermans, W. Price, J. Duncia, 1989 .

Pharmacological basis of the antihypertensive action of calcium entry blockers.

P. Timmermans, P. V. van Zwieten, 1985, Journal of cardiovascular pharmacology.

Postjunctional α‐Adrenoceptors and the Regulation of Arteriolar Tone in Humans

P. Timmermans, P. van Brummelen, P. V. van Zwieten, 1985 .