D. Stetson

D. Stetson, K. Thress, A. Markovets, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A phase 1/2 study of the combination of acalabrutinib and vistusertib in patients with relapsed/refractory B-cell malignancies

J. Vose, J. Gribben, I. Flinn, 2021, Leukemia & lymphoma.

Memory B Cell Compartment - Development and Maintenance of a B220

D. Stetson, L. McHeyzer-Williams, M. McHeyzer-Williams, 2001 .

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

R. Locksley, H. Ploegh, D. Stetson, 2001, Immunity.

Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling

A. Oberst, Michelle Brault, D. Stetson, 2018, The Journal of Immunology.

Mouse Vα14i natural killer T cells are resistant to cytokine polarization in vivo

R. Locksley, D. Stetson, M. Kronenberg, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo.

R. Locksley, D. Stetson, M. Kronenberg, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis

Dmitri I. Kotov, Bryan D. Bryson, D. Stetson, 2022, bioRxiv.

ADAR1 mutation causes ZBP1-dependent immunopathology

A. Oberst, D. Stetson, R. Savan, 2022, Nature.

Endomembrane targeting of human OAS1 p46 augments antiviral activity

Vineet D. Menachery, J. Baillie, K. Cerosaletti, 2021, bioRxiv.

ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP.

D. Stetson, J. Snyder, Daniel B. Stetson, 2022, Immunity.

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

Elizabeth E Gray, D. Stetson, A. Geballe, 2016, Immunity.

Computational design of constitutively active cGAS

M. J. Bick, Elizabeth E Gray, B. Sankaran, 2023, Nature Structural & Molecular Biology.

Development and Maintenance of a B220− Memory B Cell Compartment1

D. Stetson, L. McHeyzer-Williams, M. McHeyzer-Williams, 2001, The Journal of Immunology.

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Jonathan C. Fuller, D. Bonthron, E. Bertini, 2009, Nature Genetics.

Analysis of Ras-induced overproliferation in Drosophila hemocytes.

I. Andó, D. Stetson, C. Dearolf, 2003, Genetics.

Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

Paul M. Rindler, S. Cawley, C. Mason, 2021, Nature Biotechnology.

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

Mitchell Kronenberg, Markus Mohrs, R. Locksley, 2003, The Journal of experimental medicine.

T helper 17 cells get the NOD.

R. Medzhitov, D. Stetson, 2007, Immunity.

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

T. Heidmann, R. Medzhitov, D. Stetson, 2008, Cell.

Acquired EGFR C797S mediates resistance to AZD9291 in advanced non-small cell lung cancer harboring EGFR T790M

Aleksandra Markovets, J Carl Barrett, Geoffrey R Oxnard, 2015, Nature Medicine.

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

Elizabeth E Gray, D. Stetson, Daniel B. Stetson, 2015, Science.

Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial.

Yeon-Hee Park, D. Stetson, N. Turner, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The SKIV2L RNA exosome limits activation of the RIG-I-like receptors

Y. Crow, Elizabeth E Gray, D. Stetson, 2014, Nature Immunology.

Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.

D. Stetson, C. Connelly, J. Henao-Mejia, 2021, Immunity.

The type I interferonopathies: 10 years on

Y. Crow, D. Stetson, Daniel B. Stetson, 2021, Nature Reviews Immunology.

Endogenous Retroelements and Autoimmune Disease This Review Comes from a Themed Issue on Autoimmunity Retroelements and Autoimmunity Implications for Tissue-specific Autoimmunity

D. Stetson, Daniel B. Stetson, Y. Crow, 2022 .

Th2 cells: orchestrating barrier immunity.

D. Voehringer, R. Locksley, S. Scheu, 2004, Advances in immunology.

Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance.

Tristan J. Lubinski, J. Barrett, D. Stetson, 2019, JCO precision oncology.

Validation of ctDNA Quality Control Materials Through a Precompetitive Collaboration of the Foundation for the National Institutes of Health

C. Paweletz, K. Cole, J. Barrett, 2021, JCO precision oncology.

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease.

D. Stetson, G. Barber, K. Elkon, 2012, Immunity.

Abstract 4541:METgene copy number gains evaluated by NGS is more predictive than other methods to enrich for papillary RCC patients sensitive to savolitinib, a selective MET inhibitor

S. Signoretti, T. Choueiri, J. Barrett, 2018, Clinical Research (Excluding Clinical Trials).

Connections between antiviral defense and autoimmunity.

D. Stetson, Daniel B. Stetson, 2009, Current opinion in immunology.

Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.

W. Pao, P. Fisher, J. Dry, 2015, Cancer research.

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response.

R. Medzhitov, D. Stetson, Daniel B. Stetson, 2006, Immunity.

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

Paul M. Rindler, David P. Kreil, Paweł P. Łabaj, 2021, Genome biology.

Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer.

Thomas John, Aleksandra, Aleksandra Markovets, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

Janet M. Young, D. Stetson, I. Brodsky, 2012, The Journal of experimental medicine.

Human DNA-PK activates a STING-independent DNA sensing pathway

D. Stetson, M. Gale, R. Green, 2019, Science Immunology.

The A946T variant IFIH1 RNA sensor mediates an interferon program that limits viral infection but increases the risk for autoimmunity

D. Liggitt, P. Concannon, D. Rawlings, 2017, Nature Immunology.

PKR and the Integrated Stress Response drive immunopathology caused by ADAR1 mutation

D. Stetson, J. Henao-Mejia, J. Snyder, 2020, bioRxiv.

Tight nuclear tethering of cGAS is essential for preventing autoreactivity

Elizabeth E Gray, D. Stetson, Hannah E. Volkman, 2019, eLife.

ReviewType I Interferons in Host Defense

R. Medzhitov, D. Stetson, Daniel B. Stetson, 2022 .

Activation of the integrated stress response during T helper cell differentiation

Markus Mohrs, R. Locksley, S. Scheu, 2006, Nature Immunology.

Leishmania major LACK Antigen Is Required for Efficient Vertebrate Parasitization

R. Locksley, D. Stetson, B. Kelly, 2003, The Journal of experimental medicine.

SUMO2 and SUMO3 redundantly prevent a noncanonical type I interferon response

D. Stetson, John T. Crowl, Daniel B. Stetson, 2018, Proceedings of the National Academy of Sciences.

ABCC1/MRP1 exports cGAMP and modulates cGAS-dependent immunity

D. Stetson, J. Snyder, Daniel B. Stetson, 2021, bioRxiv.

Universal Principled Review: A Community-Driven Method to Improve Peer Review

Greg Barton, Matt Williams, Sebastian Amigorena, 2019, Cell.

Early cellular mechanism of type I interferon-driven susceptibility to tuberculosis

Dmitri I. Kotov, Bryan D. Bryson, D. Stetson, 2023, bioRxiv.

Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis

Dmitri I. Kotov, Bryan D. Bryson, D. Stetson, 2022 .

Deep oncopanel sequencing reveals fixation time- and within block position-dependent quality degradation in FFPE processed samples

Thomas M. Blomquist, C. Mason, R. Sebra, 2021, bioRxiv.

Prioritisation of structural variant calls in cancer genomes

Oliver Hofmann, Pablo Cingolani, Brad A. Chapman, 2016, bioRxiv.