Anthony J. Muslin

发表

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.

J. M. Wyss, J. Penninger, S. Heximer, 2003, The Journal of clinical investigation.

14-3-3 protein protects against cardiac endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis in experimental diabetes.

Anthony J. Muslin, R. Thandavarayan, Kenichi Watanabe, 2010, Journal of pharmacological sciences.

Akt2: A Critical Regulator of Cardiomyocyte Survival and Metabolism

Anthony J. Muslin, 2011, Pediatric Cardiology.

Swimming stress in DN 14-3-3 mice triggers maladaptive cardiac remodeling: role of p38 MAPK.

Anthony J. Muslin, P. Veeraveedu, Shaosong Zhang, 2007, American journal of physiology. Heart and circulatory physiology.

Partial Inactivation of Cardiac 14-3-3 Protein in vivo Elicits Endoplasmic Reticulum Stress (ERS) and Activates ERS-initiated Apoptosis in ERS-induced Mice

Anthony J. Muslin, R. Thandavarayan, Kenichi Watanabe, 2006, Cellular Physiology and Biochemistry.

Dominant negative 14-3-3 promotes cardiomyocyte apoptosis in early stage of type I diabetes mellitus through activation of JNK.

Anthony J. Muslin, Kenichi Watanabe, Shaosong Zhang, 2004, Biochemical and biophysical research communications.

Role of 14-3-3-Mediated p38 Mitogen-Activated Protein Kinase Inhibition in Cardiac Myocyte Survival

Anthony J. Muslin, Shaosong Zhang, Jie Ren, 2003, Circulation research.

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

P. Allen, Anthony J. Muslin, A. Shaw, 1996, Cell.

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase.

K Kornfeld, Anthony J. Muslin, D. Jacobs, 1999, Genes & development.

KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation.

Anthony J. Muslin, H. Xing, B. Bell, 1999, The Journal of biological chemistry.

The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis.

Attila Kovacs, Michael Courtois, Yibin Wang, 2003, The Journal of clinical investigation.

Phosphatidylinositol 3-kinase activity is important for progesterone-induced Xenopus oocyte maturation

A. Klippel, Anthony J. Muslin, L. Williams, 1993, Molecular and cellular biology.

Regulation of Raf-1-dependent signaling during early Xenopus development

Anthony J. Muslin, L. Williams, A. Kikuchi, 1995, Molecular and cellular biology.

Septic Shock Induced From An Implantable Cardioverter-Defibrillator Lead-Associated Candida albicans Vegetation

Anthony J. Muslin, S. Hindupur, 2005, Journal of Interventional Cardiac Electrophysiology.

Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos

Anthony J. Muslin, L. Williams, A. MacNicol, 1993, Molecular and cellular biology.

Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF

Anthony J. Muslin, L. Williams, A. MacNicol, 1993, Cell.

Raf-1 Kinase Is Required for Cardiac Hypertrophy and Cardiomyocyte Survival in Response to Pressure Overload

Anthony J. Muslin, Shaosong Zhang, I. Treskov, 2004, Circulation.

Chapter 37 – The Pathophysiology of Heart Failure

Anthony J. Muslin, 2012 .

Role of 14-3-3 protein and oxidative stress in diabetic cardiomyopathy.

Anthony J. Muslin, R. Thandavarayan, Kenichi Watanabe, 2009, Acta physiologica Hungarica.

Role of raf proteins in cardiac hypertrophy and cardiomyocyte survival.

Anthony J. Muslin, 2005, Trends in cardiovascular medicine.

Cation Diffusion Facilitator Proteins Modulate Raf-1 Activity*

Anthony J. Muslin, T. Jirakulaporn, 2004, Journal of Biological Chemistry.

RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice.

G. Dorn, Anthony J. Muslin, K. Blumer, 2001, Journal of molecular and cellular cardiology.

RGS4 inhibits G-protein signaling in cardiomyocytes.

Anthony J. Muslin, K. Blumer, P. Tamirisa, 1999, Circulation.

Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure.

Anthony J. Muslin, A. Siedlecki, Xiaohua Jin, 2009, Kidney international.

Akt1 Is Required for Physiological Cardiac Growth

Anthony J. Muslin, C. Weinheimer, M. Courtois, 2006, Circulation.

Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange.

R. Alexander, Anthony J. Muslin, B. Berk, 1989, The Journal of clinical investigation.

An Unbiased Chemical Biology Screen Identifies Agents That Modulate Uptake of Oxidized LDL by Macrophages

Anthony J. Muslin, Jie Ren, Y. Etzion, 2009, Circulation research.

14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy.

Anthony J. Muslin, P. Veeraveedu, S. Palaniyandi, 2008, Biochemical pharmacology.

Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity.

Anthony J. Muslin, Y. Etzion, S. Etzion, 2010, Journal of molecular and cellular cardiology.

New insights into cardiac aging.

Anthony J. Muslin, 2009, Circulation.

PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo

M. Krempf, Anthony J. Muslin, D. Blom, 2016, JACC. Basic to translational science.

Modulation of doxorubicin-induced cardiac dysfunction in dominant-negative p38α mitogen-activated protein kinase mice.

Anthony J. Muslin, R. Thandavarayan, Kenichi Watanabe, 2010, Free radical biology & medicine.

Akt2 Regulates Cardiac Metabolism and Cardiomyocyte Survival*

Anthony J. Muslin, C. Weinheimer, M. Courtois, 2006, Journal of Biological Chemistry.

Dominant-negative p 38 mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus

Anthony J. Muslin, P. Veeraveedu, R. Thandavarayan, 2009 .

Dominant-negative p38alpha mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus.

Anthony J. Muslin, P. Veeraveedu, R. Thandavarayan, 2009, American journal of physiology. Heart and circulatory physiology.

Dominant-negative p38 (cid:1) mitogen-activated protein kinase prevents cardiac apoptosis and remodeling after streptozotocin-induced diabetes mellitus

Anthony J. Muslin, P. Veeraveedu, R. Thandavarayan, 2009 .

A salutary role for calcineurin in the heart.

Anthony J. Muslin, 2010, Journal of Molecular and Cellular Cardiology.

Grb2 Is Required for the Development of Neointima in Response to Vascular Injury

Anthony J. Muslin, Shaosong Zhang, Jie Ren, 2003, Arteriosclerosis, thrombosis, and vascular biology.

RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm

Anthony J. Muslin, U. V. von Andrian, J. Bonventre, 2014, Kidney international.

Attenuation of CHOP-mediated Myocardial Apoptosis in Pressure-overloaded Dominant Negative p38α Mitogen-activated Protein Kinase Mice

Kenji Suzuki, Anthony J. Muslin, R. Thandavarayan, 2011, Cellular Physiology and Biochemistry.

A G protein–biased S1P1 agonist, SAR247799, protects endothelial cells without affecting lymphocyte numbers

Anthony J. Muslin, P. Wohlfart, D. Kadereit, 2020, Science Signaling.

RGS3 and RGS4 are GTPase activating proteins in the heart.

J. Rottman, Anthony J. Muslin, K. Blumer, 1998, Journal of molecular and cellular cardiology.

Serine 58 of 14-3-3 (cid:2) Is a Molecular Switch Regulating ASK1 and Oxidant Stress-Induced Cell Death (cid:1) †

Anthony J. Muslin, H. Ichijo, Jibin Zhou, 2009 .

Road Rage: Cardiac Rab1 and ER-to-Golgi Traffic.

Anthony J. Muslin, 2001, Circulation research.

Glycogen synthase kinase 3β together with 14‐3‐3 protein regulates diabetic cardiomyopathy: Effect of losartan and tempol

Anthony J. Muslin, Kenichi Watanabe, Shaosong Zhang, 2006, FEBS letters.

First‐in‐human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G‐protein‐biased sphingosine‐1 phosphate receptor‐1 agonist for endothelial protection

P. Deutsch, L. Bergougnan, Anthony J. Muslin, 2020, British journal of clinical pharmacology.

Direct Activation of Phospholipase C-y by Fibroblast Growth Factor Receptor Is Not Required for Mesoderm

Anthony J. Muslin, L. Williams, K. Peters, 2022 .

Requirement for p38 Mitogen-Activated Protein Kinase Activity in Neointima Formation After Vascular Injury

L. Muglia, Anthony J. Muslin, C. Semenkovich, 2008, Circulation.

RGS proteins inhibit Xwnt-8 signaling in Xenopus embryonic development.

Anthony J. Muslin, K. Blumer, C. Wu, 2000, Development.

Direct Activation ofPhospholipase C-ybyFibroblast Growth Factor Receptor IsNotRequired forMesoderm Induction inXenopus AnimalCaps

Anthony J. Muslin, 1994 .

ZnT-1 protects HL-1 cells from simulated ischemia–reperfusion through activation of Ras–ERK signaling

Anthony J. Muslin, A. Katz, Y. Etzion, 2011, Journal of molecular medicine.

Beta3 integrin deficiency promotes cardiac hypertrophy and inflammation.

J. Schneider, Anthony J. Muslin, F. Ross, 2007, Journal of molecular and cellular cardiology.

ZnT-1 protects HL-1 cells from simulated ischemia–reperfusion through activation of Ras–ERK signaling

Anthony J. Muslin, A. Katz, Y. Etzion, 2011, Journal of Molecular Medicine.

oocyte maturation. important for progesterone-induced Xenopus Phosphatidylinositol 3-kinase activity is

A. Klippel, Anthony J. Muslin, L. Williams, 2013 .

RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation.

Douglas M. Yau, Anthony J. Muslin, N. Dulin, 2013, American journal of physiology. Lung cellular and molecular physiology.

Role of Akt in cardiac growth and metabolism.

Anthony J. Muslin, B. Debosch, Brian Debosch, 2006, Novartis Foundation symposium.

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.

Anthony J. Muslin, Anthony J Muslin, 2008, Clinical science.

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.

W. Fantl, A. Klippel, Anthony J. Muslin, 1995, Science.

14‐3‐3 proteins block apoptosis and differentially regulate MAPK cascades

Anthony J. Muslin, H. Xing, A. Kovács, 2000, The EMBO journal.

Getting the iron out: preventing and treating heart failure in transfusion-dependent thalassemia.

Anthony J. Muslin, G. Davison, Danish A Jabbar, 2007, Cleveland Clinic journal of medicine.

Ajuba, a Novel LIM Protein, Interacts with Grb2, Augments Mitogen-Activated Protein Kinase Activity in Fibroblasts, and Promotes Meiotic Maturation of Xenopus Oocytes in a Grb2- and Ras-Dependent Manner

Anthony J. Muslin, G. Longmore, P. Lin, 1999, Molecular and Cellular Biology.

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

S. Korsmeyer, Anthony J. Muslin, T. Kawabe, 1997, Nature.

KSR-1 Binds to G-protein βγ Subunits and Inhibits βγ-induced Mitogen-activated Protein Kinase Activation*

Anthony J. Muslin, H. Xing, B. Bell, 1999, The Journal of Biological Chemistry.

Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling.

Anthony J. Muslin, K. Kornfeld, T. Jirakulaporn, 2002, Developmental cell.

Role of 14-3-3 proteins in early Xenopus development

Anthony J. Muslin, Chunlai Wu, 2002, Mechanisms of Development.

Disruption of the 14-3-3 Binding Site within the B-Raf Kinase Domain Uncouples Catalytic Activity from PC12 Cell Differentiation*

Anthony J. Muslin, A. MacNicol, M. MacNicol, 2000, The Journal of Biological Chemistry.

14-3-3 proteins: regulation of subcellular localization by molecular interference.

Anthony J. Muslin, H. Xing, 2000, Cellular signalling.

Activation of Raf-1 by 14-3-3 proteins

W. Fantl, Anthony J. Muslin, L. Williams, 1994, Nature.

The 14-3-3τ Phosphoserine-Binding Protein Is Required for Cardiomyocyte Survival

Anthony J. Muslin, Jie Ren, I. Treskov, 2006, Molecular and Cellular Biology.

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

J. Schneider, M. Takagi, M. Kastan, 2006, Cell metabolism.

TRB3 Function in Cardiac Endoplasmic Reticulum Stress

Anthony J. Muslin, A. Kovács, S. Etzion, 2010, Circulation research.

Well-defined growth factors promote cardiac development in axolotl mesodermal explants.

Anthony J. Muslin, L. Williams, 1991, Development.

The physician scientist training program in internal medicine at Washington University School of Medicine.

Stuart A Kornfeld, K. Polonsky, Anthony J. Muslin, 2009, Academic medicine : journal of the Association of American Medical Colleges.

The protein kinase KSR interacts with 14-3-3 protein and Raf

Anthony J. Muslin, H. Xing, K. Kornfeld, 1997, Current Biology.

Differential role of 14‐3‐3 family members in Xenopus development

Anthony J. Muslin, Jeffrey M. C. Lau, Chunlai Wu, 2006, Developmental dynamics : an official publication of the American Association of Anatomists.

Nuclear Localization of Protein Kinase U-α Is Regulated by 14-3-3*

Anthony J. Muslin, H. Xing, S. Zhang, 1999, The Journal of Biological Chemistry.

Stress-Induced Cell Death Regulating ASK1 and Oxidant Is a Molecular Switch ζ Serine 58 of 14-3-3

Anthony J. Muslin, H. Ichijo, T. Force, 2014 .

Serine 58 of 14-3-3ζ Is a Molecular Switch Regulating ASK1 and Oxidant Stress-Induced Cell Death

Anthony J. Muslin, H. Ichijo, T. Force, 2009, Molecular and Cellular Biology.

Endothelial‐protective effects of a G‐protein‐biased sphingosine‐1 phosphate receptor‐1 agonist, SAR247799, in type‐2 diabetes rats and a randomized placebo‐controlled patient trial

P. Deutsch, L. Bergougnan, Anthony J. Muslin, 2020, medRxiv.

Ras‐interacting domain of RGL blocks Ras‐dependent signal transduction in Xenopus oocytes

Anthony J. Muslin, L. Williams, A. Kikuchi, 1996, FEBS letters.

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.

J. Penninger, S. Heximer, R. Knutsen, 2003, The Journal of clinical investigation.

Phenotypic High-Throughput Screening in Atherosclerosis Research: Focus on Macrophages

Anthony J. Muslin, 2010, Journal of cardiovascular translational research.

Differential functions of 14-3-3 isoforms in vertebrate development.

Anthony J. Muslin, Jeffrey M. C. Lau, 2005, Current topics in developmental biology.

RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload.

Anthony J. Muslin, K. Blumer, D. Kelly, 1999, The Journal of clinical investigation.

Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction.

Jie Ren, Attila Kovacs, Yibin Wang, 2005, Journal of molecular and cellular cardiology.

Insulin signaling pathways and cardiac growth.

Anthony J. Muslin, Brian Debosch, 2008, Journal of molecular and cellular cardiology.

Inactivation of 14-3-3 protein exacerbates cardiac hypertrophy and fibrosis through enhanced expression of protein kinase C beta 2 in experimental diabetes.

Anthony J. Muslin, Kenichi Watanabe, Shaosong Zhang, 2005, Biological & pharmaceutical bulletin.

Direct activation of phospholipase C-gamma by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps

Anthony J. Muslin, L. Williams, K. Peters, 1994, Molecular and cellular biology.

Molecular Basis for Zinc Transporter 1 Action as an Endogenous Inhibitor of L-type Calcium Channels*

Levi A. Gheber, L. Shaltiel, Anthony J. Muslin, 2009, The Journal of Biological Chemistry.

The application of phenotypic high-throughput screening techniques to cardiovascular research.

Anthony J. Muslin, Y. Etzion, 2009, Trends in cardiovascular medicine.

G-protein signaling participates in the development of diabetic cardiomyopathy.

S. Heximer, K. Kaltenbronn, Anthony J. Muslin, 2004, Diabetes.

Signaling molecules that mediate the actions of FGF.

S. Demo, Anthony J. Muslin, L. Williams, 1994, Princess Takamatsu symposia.

Tuning cardiomyocyte Gq signaling with RGS2.

Anthony J. Muslin, 2006, Journal of molecular and cellular cardiology.

RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury.

Anthony J. Muslin, K. Hruska, W. Thomas, 2011, Kidney international.

Evidence for both tyrosine kinase and G-protein-coupled pathways leading to starfish egg activation.

D. J. Carroll, Anthony J. Muslin, J. Escobedo, 1994, Developmental biology.

Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy.

M. Pruniaux, Anthony J. Muslin, O. Dorchies, 2019, Cardiovascular research.

Is Required for Cardiomyocyte Survival Phosphoserine-Binding Protein τ The 14-3-3

Anthony J. Muslin, Jie Ren, I. Treskov, 2014 .

Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos.

Anthony J. Muslin, Jeffrey M. C. Lau, 2009, Methods in molecular biology.

TRB 3 Function in Cardiac Endoplasmic Reticulum Stress

Anthony J. Muslin, A. Kovács, S. Etzion, 2010 .

Cardiovascular Therapeutic Discovery

Anthony J. Muslin, B. Blaxall, 2010, Journal of cardiovascular translational research.

MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.

Anthony J. Muslin, 2008, Clinical science.

Grb2 Is Required for Atherosclerotic Lesion Formation

J. Schneider, Anthony J. Muslin, Jie Ren, 2007, Arteriosclerosis, thrombosis, and vascular biology.

RGS4 Controls Renal Blood Flow and Inhibits Cyclosporine‐Mediated Nephrotoxicity

Anthony J. Muslin, J. Garbow, Traian S. Lupu, 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

An Unbiased Chemical Biology Screen Identifies Agents That Modulate Uptake of Oxidized LDL by Macrophages

Anthony J. Muslin, Jie Ren, Y. Etzion, 2009, Circulation research.