J. Villanueva

发表

Differential exoprotease activities confer tumor-specific serum peptidome patterns.

A. Olshen, C. Cordon-Cardo, J. Boyd, 2005, The Journal of clinical investigation.

Serum peptide profiling by magnetic particle-assisted, automated sample processing and MALDI-TOF mass spectrometry.

E. Holland, P. Tempst, J. Villanueva, 2004, Analytical chemistry.

Correcting common errors in identifying cancer-specific serum peptide signatures.

P. Tempst, J. Villanueva, J. Philip, 2005, Journal of proteome research.

Automated serum peptide profiling

P. Tempst, J. Villanueva, R. Toledo-Crow, 2006, Nature Protocols.

Serum Peptidome Patterns That Distinguish Metastatic Thyroid Carcinoma from Cancer-free Controls Are Unbiased by Gender and Age*S

P. Tempst, J. Villanueva, J. Philip, 2006, Molecular & Cellular Proteomics.

A Sequence-specific Exopeptidase Activity Test (SSEAT) for “Functional” Biomarker Discovery*S

P. Tempst, J. Villanueva, R. Robbins, 2008, Molecular & Cellular Proteomics.

Monitoring peptidase activities in complex proteomes by MALDI-TOF mass spectrometry

P. Tempst, J. Villanueva, K. Lawlor, 2009, Nature Protocols.

Enhancing the Biological Relevance of Secretome-Based Proteomics by Linking Tumor Cell Proliferation and Protein Secretion.

J. Tabernero, J. Arribas, J. Villanueva, 2014, Journal of proteome research.

Tumor and Stem Cell Biology Constitutive HER 2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence

R. Gomis, J. Tabernero, J. Arribas, 2012 .

Inhibition of Circulating Dipeptidyl Peptidase 4 Activity in Patients with Metastatic Prostate Cancer*

A. Saghatelian, J. Eastham, A. Vickers, 2014, Molecular & Cellular Proteomics.

Hitting the brakes on autophagy for overcoming acquired resistance in triple negative breast cancer.

J. Villanueva, Chiara Bellio, C. Bellio, 2020, Annals of translational medicine.

Analysis of the effect of potato carboxypeptidase inhibitor pro-sequence on the folding of the mature protein.

E. Querol, F. Avilés, J. Villanueva, 2003, European journal of biochemistry.

Effect of cellular senescence on the growth of HER2-positive breast cancers.

J. Arribas, J. Villanueva, I. Rubio, 2015, Journal of the National Cancer Institute.

Clinical Implications of Extracellular HMGA1 in Breast Cancer

J. Villanueva, J. Cortés, O. Méndez, 2019, International journal of molecular sciences.

GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells

J. Tabernero, E. Zamora, J. Arribas, 2022, Cancers.

Characterization of the wound‐induced metallocarboxypeptidase inhibitor from potato 1

E. Querol, F. Avilés, J. Villanueva, 1998 .

Non-linear effects in the determination of paleotemperature U37(k') alkenone ratios by chemical ionization mass spectrometry.

J. Grimalt, J. Villanueva, R. Chaler, 2003, Journal of chromatography. A.

Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence

J. Arribas, J. Villanueva, Águeda Martínez-Barriocanal, 2015, Breast Cancer Research.

Package ‘msmsTests’

J. Villanueva, J. Gregori, Àlex Sánchez, 2022 .

Thermal Rearrangement of 1,4-Dinitroimidazole to 2,4-Dinitroimidazole: Characterization and Investigation of the Mechanism by Mass Spectrometry and Isotope Labeling

R. Behrens, J. Villanueva, S. Bulusu, 1995 .

Detection of non-covalent protein interactions by 'intensity fading' MALDI-TOF mass spectrometry: applications to proteases and protease inhibitors

E. Querol, F. Avilés, J. Villanueva, 2007, Nature Protocols.

Functional Screening of Serine Protease Inhibitors in the Medical Leech Hirudo medicinalis Monitored by Intensity Fading MALDI-TOF MS*

Enrique Querol, Oscar Yanes, Francesc X. Aviles, 2005, Molecular & Cellular Proteomics.

Intensity-fading MALDI-TOF-MS: novel screening for ligand binding and drug discovery

Francesc X. Avilés, Enrique Querol, Oscar Yanes, 2004 .

Identification of protein ligands in complex biological samples using intensity-fading MALDI-TOF mass spectrometry.

Enrique Querol, Oscar Yanes, Francesc X Aviles, 2003, Analytical chemistry.

HMGA1, Moonlighting Protein Function, and Cellular Real Estate: Location, Location, Location!

J. Villanueva, L. Resar, Mireia Pujals, 2021, Biomolecules.

Extracellular HMGA1 Promotes Tumor Invasion and Metastasis in Triple-Negative Breast Cancer

J. Tabernero, S. Schwartz, J. Arribas, 2018, Clinical Cancer Research.

Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence

J. Arribas, J. Villanueva, Águeda Martínez-Barriocanal, 2015, Breast Cancer Research.

Pathway-based biomarker search by high-throughput proteomics profiling of secretomes.

Paul Tempst, Josep Villanueva, Lynne Lacomis, 2009, Journal of proteome research.

Multiple insect resistance in transgenic tomato plants over-expressing two families of plant proteinase inhibitors

J. Villanueva, S. Prat, R. Gabarra, 2004, Plant Molecular Biology.

Challenges and opportunities for cell line secretomes in cancer proteomics

J. Villanueva, O. Méndez, 2015, Proteomics. Clinical applications.

An effect size filter improves the reproducibility in spectral counting-based comparative proteomics.

Alex Sánchez, José Baselga, Josep Villanueva, 2013, Journal of proteomics.

Unconventional Secretion is a Major Contributor of Cancer Cell Line Secretomes*

J. Baselga, J. Villanueva, L. Villarreal, 2012, Molecular & Cellular Proteomics.

Batch effects correction improves the sensitivity of significance tests in spectral counting-based comparative discovery proteomics.

Josep Villanueva, Josep Gregori, Laura Villarreal, 2012, Journal of proteomics.

STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation

J. Villanueva, R. Selgas, J. Lizcano, 2020, Communications Biology.

Circulating SOD2 Is a Candidate Response Biomarker for Neoadjuvant Therapy in Breast Cancer

E. Zamora, J. Villanueva, Alex Sánchez-Pla, 2022, Cancers.

Targeting PML in triple negative breast cancer elicits growth suppression and senescence

I. Heřmanová, J. Villanueva, R. Barrio, 2019, Cell Death & Differentiation.

msmsTests package LC-MS/MS post test ﬁlters to improve reproducibility

J. Villanueva, J. Gregori, Vall, 2013 .

Circulating pEGFR Is a Candidate Response Biomarker of Cetuximab Therapy in Colorectal Cancer

A. Bardelli, J. Tabernero, J. Villanueva, 2014, Clinical Cancer Research.

Personalized Medicine and Imaging Circulating pEGFR Is a Candidate Response Biomarker of Cetuximab Therapy in Colorectal Cancer

A. Bardelli, J. Tabernero, J. Villanueva, 2014 .

Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells

E. Blanco, P. Nuciforo, R. Dienstmann, 2020, bioRxiv.

Distilling cancer biomarkers from the serum peptidome: high technology reading of tea leaves or an insight to clinical systems biology?

P. Tempst, J. Villanueva, R. Robbins, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Characterization of the wound-induced metallocarboxypeptidase inhibitor from potato. cDNA sequence, induction of gene expression, subcellular immunolocalization and potential roles of the C-terminal propeptide.

E. Querol, F. X. Avilés, J. Villanueva, 1998, FEBS letters.

Serum Proteomic Abnormality Predating Screen Detection of Ovarian Cancer

Alexander Gammerman, Vladimir Vovk, Ilia Nouretdinov, 2009, Comput. J..

Hydrogen exchange monitored by MALDI‐TOF mass spectrometry for rapid characterization of the stability and conformation of proteins

E. Querol, F. Avilés, J. Villanueva, 2000, FEBS letters.

Monitoring disappearance of monomers and generation of resistance to proteolysis during the formation of the activation domain of human procarboxypeptidase A2 (ADA2h) amyloid fibrils by matrix-assisted laser-desorption ionization-time-of-flight-MS.

L. Serrano, E. Querol, F. Avilés, 2003, The Biochemical journal.

Protein secondary structure and stability determined by combining exoproteolysis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Enrique Querol, Josep Villanueva, Luis Serrano, 2002, Journal of mass spectrometry : JMS.

Domain swapping in p13suc1 results in formation of native-like, cytotoxic aggregates.

L. Serrano, L. Itzhaki, H. Wilkinson, 2006, Journal of molecular biology.

msmsEDA and msmsTests: R/Bioconductor packages for spectral count label-free proteomics data analysis

Josep Gregori, Alex Sánchez, Josep Villanueva, 2014 .

Data analysis of assorted serum peptidome profiles

Paul Tempst, John Philip, Josep Villanueva, 2007, Nature Protocols.

msmsEDA & msmsTests: Label-Free Differential Expression by Spectral Counts.

J. Villanueva, J. Gregori, Àlex Sánchez, 2023, Methods in molecular biology.

Analysis of Protein—Protein Interactions in Complex Biological Samples by MALDI TOF MS. Feasibility and Use of the Intensity-Fading (IF-) Approach

Francesc X. Avilés, Enrique Querol, Josep Villanueva, 2004 .

RAGE/SNAIL1 signaling drives epithelial-mesenchymal plasticity in metastatic triple-negative breast cancer

L. Padilla, F. Mitjans, J. Tabernero, 2023, Oncogene.

Ligand screening by exoproteolysis and mass spectrometry in combination with computer modelling.

Enrique Querol, Francesc X Aviles, Josep Villanueva, 2003, Journal of molecular biology.

PI3K-based molecular signatures link high PI3K pathway activity with low ER levels in ER+ breast cancer

J. Villanueva, Àlex Sánchez, 2010, Expert review of proteomics.

Monitoring the expression and purification of recombinant proteins by MALDI-TOF mass spectrometry.

E. Querol, F. X. Avilés, J. Villanueva, 2001, Enzyme and microbial technology.