A. Tulinsky

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Phase refinement/extension by density modification

A. Tulinsky, 1985 .

Formation, crystallization, and preliminary crystallographic data of the ternary complex of alpha-chymotrypsin, beta-trypsin, and the Bowman-Birk inhibitor.

A. Tulinsky, I. Liener, J. Gaier, 1981, The Journal of biological chemistry.

The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.

A. Tulinsky, J. Sadler, A Tulinsky, 1994, The Journal of biological chemistry.

The structure of a complex of recombinant hirudin and human alpha-thrombin.

R. Huber, W. Bode, A. Tulinsky, 1990, Science.

Intermolecular interactions and characterization of the novel factor Xa exosite involved in macromolecular recognition and inhibition: crystal structure of human Gla-domainless factor Xa complexed with the anticoagulant protein NAPc2 from the hematophagous nematode Ancylostoma caninum.

A. Tulinsky, R. Arni, J. Geiger, 2007, Journal of molecular biology.

Structure of aquomagnesium tetraphenylporphyrin

A. Tulinsky, R. Timkovich, 1969 .

Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties.

R. Nutt, S. Tamura, A. Tulinsky, 1996, Journal of medicinal chemistry.

The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1.

A. D. de Vos, A. Tulinsky, M. Soriano-garcia, 1994, Biochemistry.

Structure of the non-covalent complex of prothrombin kringle 2 with PPACK-thrombin.

A. Tulinsky, R. Arni, K. Padmanabhan, 1994, Chemistry and physics of lipids.

Functions of individual gamma-carboxyglutamic acid (Gla) residues of human protein c. Determination of functionally nonessential Gla residues and correlations with their mode of binding to calcium.

A. Tulinsky, F. Castellino, W. T. Christiansen, 1994, Biochemistry.

An ambiguous structure of a DNA 15-mer thrombin complex.

A. Tulinsky, K. Padmanabhan, 1996, Acta crystallographica. Section D, Biological crystallography.

Expression of functionality of alpha-chymotrypsin. Effects of guanidine hydrochloride and urea in the onset of denaturation.

L. Hibbard, A. Tulinsky, 1978, Biochemistry.

Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.

M. Ultsch, R. Kelley, A. D. de Vos, 1992, Biochemistry.

Crystallization and preliminary diffraction data of a platelet-aggregation inhibitor from the venom of Agkistrodon piscivorus piscivorus (North American water moccasin).

A. Tulinsky, R. Arni, K. Padmanabhan, 1999, Acta crystallographica. Section D, Biological crystallography.

The crystal and molecular structure of triclinic tetraphenylporphyrin.

A. Tulinsky, S. Silvers, 1967, Journal of the American Chemical Society.

The isomorphous structures of prethrombin2, hirugen–, and PPACK–thrombin: Changes accompanying activation and exosite binding to thrombin

K. Mann, A. Tulinsky, K. Padmanabhan, 1994, Protein science : a publication of the Protein Society.

Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.

A. Tulinsky, E. Skrzypczak‐Jankun, J. Maraganore, 1991, Journal of molecular biology.

The refined structure of the epsilon-aminocaproic acid complex of human plasminogen kringle 4.

A. Tulinsky, A. Mulichak, K. Padmanabhan, 1991, Biochemistry.

Lysine/fibrin binding sites of kringles modeled after the structure of kringle 1 of prothrombin

A. Tulinsky, B. Mao, Chang H. Park, 1988, Proteins.

Active-site mimetic inhibition of thrombin.

A. Tulinsky, I. Mathews, 1995, Acta crystallographica. Section D, Biological crystallography.

Crystallographic structure of human gamma-thrombin.

A. Tulinsky, A. Cardin, K. Padmanabhan, 1994, The Journal of biological chemistry.

Proton magnetic resonance study of lysine-binding to the kringle 4 domain of human plasminogen. The structure of the binding site.

A. Petros, M. Llinás, A. Tulinsky, 1987, Journal of molecular biology.

Confirmation of a trimeric subunit arrangement for 2-keto-3-deoxy-6-phosphogluconic aldolase using x-ray crystallographic methods.

A. Tulinsky, W. Wood, R. Vandlen, 1973, The Journal of biological chemistry.

Mechanisms of Arg-Pro-Pro-Gly-Phe inhibition of thrombin.

A. Schmaier, A. Tulinsky, S. Srikanth, 2003, American journal of physiology. Heart and circulatory physiology.

Comparison of ligand-binding sites of modeled apo[a] kringle-like sequences in human lipoprotein[a].

A. Tulinsky, J. Morrisett, A. Jan, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

Three-dimensional structure of the kringle sequence: structure of prothrombin fragment 1.

A. Tulinsky, C. Park, 1986, Biochemistry.

Basic beryllium acetate. I. The collection of intensity data

A. Tulinsky, C. R. Worthington, F. Pignataro, 1959 .

Proposed mechanisms for binding of apo[a] kringle type 9 to apo B-100 in human lipoprotein[a].

J. Spurlino, B. Prasad, A. Tulinsky, 1993, Biophysical journal.

Kringle‐kringle interactions in multimer kringle structures

A. Tulinsky, K. Ravichandran, K. Padmanabhan, 1994, Protein science : a publication of the Protein Society.

Preliminary crystallographic data and quaternary structural implications of the central subunit of the multi-subunit complex transcarboxylase.

A. Tulinsky, E. Skrzypczak‐Jankun, H. Wood, 1986, Journal of molecular biology.

The monoclinic structure of a fluorescent probe: ammonium 1-anilino-8-naphthalenesulfonate (ANS) monohydrate

A. Tulinsky, L. D. Weber, 1980 .

Rigid-body torsional vibrations in three typical members of a class of benzene derivatives

A. Tulinsky, John G. White, J. White, 1958 .

Biochemical and functional characterization of human tissue-type plasminogen activator variants with mutagenized kringle domains.

L. Nelles, A. Vandamme, A. Tulinsky, 1990, The Journal of biological chemistry.

CRYSTAL AND MOLECULAR STRUCTURE OF DIMETHOXYPORPHINATO‐GERMANIUM(IV)

A. Tulinsky, A. Mavridis, 1977 .

Crystallization and preliminary diffraction data of Escherichia coli ADP glucose pyrophosphorylase.

A. Tulinsky, J. Preiss, E. Skrzypczak‐Jankun, 1988, The Journal of biological chemistry.

Interaction of alpha-chymotrypsin with the fluorescent probe 1-anilinonaphthalene-8-sulfonate in solution.

A. Tulinsky, J. Johnson, M. El-Bayoumi, 1979, Biochemistry.

Crystal structures of thrombin with thiazole-containing inhibitors: probes of the S1' binding site.

J H Matthews, A. Tulinsky, B. Maryanoff, 1996, Biophysical journal.

Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution.

A. Tulinsky, A. Mulichak, K. Ravichandran, 1991, Biochemistry.

Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.

A. Tulinsky, I. Mathews, F. Castellino, 1996, Biochemistry.

Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum.

A. Tulinsky, R. Arni, M. Murakami, 2007, Journal of molecular biology.

Interaction of Calcium with Native and Decarboxylated Human Factor X.

A. Tulinsky, S. Bajaj, K. Padmanabhan, 1997, The Journal of Biological Chemistry.

Structure of Thrombin Inhibited by Aeruginosin 298-A from a Blue-Green Alga

A. Tulinsky, Alexander Tulinsky, Masahiro Murakami, 1998 .

Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1.

R. Nutt, A. Tulinsky, E. Dempsey, 1996, Journal of medicinal chemistry.

Comparison of the crystal structures of a flavodoxin in its three oxidation states at cryogenic temperatures.

K D Watenpaugh, A. Tulinsky, K. Watenpaugh, 1993, Journal of molecular biology.

Crystal and molecular structure of cofacial dicopper hexyldiporphyrin-7

M. Hatada, A. Tulinsky, C. Chang, 1980 .

The Triclinic Crystal Form of α,β,γ,δ-Tetraphenylporphine

A. Tulinsky, S. Silvers, 1964 .

Direct Analysis of Differaction by Matter.

A. Tulinsky, 1963 .

The Structure of Mitomycin A

A. Tulinsky, 1962 .

Crystal and molecular structure of anthracene and biphenylene pillared cofacial diporphyrins.

A. Tulinsky, K. Ravichandran, I. Abdalmuhdi, 1986, Journal of the American Chemical Society.

The crystal and molecular structure of n-brosylmitomycin A.

A. Tulinsky, J. H. van den Hende, 1967, Journal of the American Chemical Society.

The calcium ion and membrane binding structure of the Gla domain of calcium-prothrombin fragment 1

A. Tulinsky, M. Soriano-garcia, A. D. Vos, 1992 .

The Dimeric Complex of Beta-Cyclodextrin with 1,13-tridecanedioic acid

A. Tulinsky, I. Mavridis, S. Makedonopoulou, 1999 .

Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites.

A. Tulinsky, R. Arni, R. Arni, 1992, Biochemistry.

Crystal and molecular structure of cofacial dicopper hexyldiporphyrin-7

M. Hatada, A. Tulinsky, C. Chang, 1980 .

Molecular Interactions of Thrombin.

A. Tulinsky, A Tulinsky, 1996, Seminars in thrombosis and hemostasis.

Crystal and molecular structure of tetrakis(2,2,6,6-tetramethyl-3,5-heptanedionato)niobium(IV). Square antiprismatic M(bidentate)4 stereoisomer

A. Tulinsky, T. Pinnavaia, B. Barnett, 1975 .

The x-ray structure determination of thujic acid (7,7-dimethylcycloheptatriene-3-carboxylic acid).

Raymond E. Davis, A. Tulinsky, 1966, Journal of the American Chemical Society.

Two independent determinations of the crystal and molecular structure of the iodine monochloride complex of pentamethylenetetrazole

A. I. Popov, A. Tulinsky, N. Baenziger, 1967 .

Basic beryllium acetate. II. The structure analysis

A. Tulinsky, C. R. Worthington, 1959 .

Structure of 2-keto-3-deoxy-6-phosphogluconate aldolase at 2 . 8 A resolution.

M. Hatada, L. Lebioda, A. Tulinsky, 1978, Journal of molecular biology.

The folding and quaternary structure of trimeric 2-keto-3-deoxy-6-phosphogluconic aldolase at 3.5-A resolution.

A. Tulinsky, I. Mavridis, 1976, Biochemistry.

The Structure of Isoquinocycline A. An X-Ray Crystallographic Determination

A. Tulinsky, 1964 .

Variability in the tertiary structure of alpha-chymotrypsin at 2.8-A resolution.

L. H. Wright, C. Morimoto, A. Tulinsky, 1973, Biochemistry.

Potent thrombin inhibitors that probe the S1 subsite: tripeptide transition state analogues based on a heterocycle-activated carbonyl group.

A. Tulinsky, B. Maryanoff, M. J. Costanzo, 1996, Journal of medicinal chemistry.

X-Ray Crystal Structures of Human α-Thrombin and of the Human Thrombin-Hirudin Complex

R. Huber, W. Bode, A. Tulinsky, 1992 .

Comparison of the structures of the cyclotheonamide a complexes of human α‐thrombin and bovine β‐trypsin

J. Clardy, A. Tulinsky, V. Ganesh, 1996, Protein science : a publication of the Protein Society.

Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A.

K C Nicolaou, K. Nicolaou, A. Liu, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Refined structure of the hirudin-thrombin complex.

R. Huber, W. Bode, A. Tulinsky, 1991, Journal of molecular biology.

Human d-Phe-Pro-Arg-CH2-α-thrombin crystallization and diffraction data

K. Mann, A. Tulinsky, E. Skrzypczak‐Jankun, 1989 .

Structure of human des(1-45) factor Xa at 2.2 A resolution.

R. Huber, W. Kisiel, W. Bode, 1993, Journal of molecular biology.

Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.

A. Tulinsky, R. Vandlen, 1973, Biochemistry.

Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.

C W Turck, C. Turck, J. Chen, 1994, Biochemistry.

Expression of functionality of alpha-chymotrypsin. The structure of a fluorescent probe--alpha-chymotrypsin complex and the nature of its pH dependence.

A. Tulinsky, J. Johnson, L. D. Weber, 1979, Biochemistry.

Preliminary x-ray investigation of an orthorhombic crystal of hevein.

A. Tulinsky, M. Soriano-garcia, B. Arreguín, 1988, Journal of Biological Chemistry.

Electrostatic interactions in the association of proteins: An analysis of the thrombin–hirudin complex

W. Bode, A. Tulinsky, S. Stone, 1992, Protein science : a publication of the Protein Society.

Structure of bovine prothrombin fragment 1 refined at 2.25 A resolution.

A. Tulinsky, E. Skrzypczak‐Jankun, T. Seshadri, 1991, Journal of molecular biology.

Structure of tetra-n-propylporphine. An average structure for the free base macrocycle from three independent determinations.

P. W. Codding, A. Tulinsky, 1972, Journal of the American Chemical Society.

Comparison of the folding of 2-keto-3-deoxy-6-phosphogluconate aldolase, triosephosphate isomerase and pyruvate kinase. Implications in molecular evolution.

M. Hatada, L. Lebioda, A. Tulinsky, 1982, Journal of molecular biology.

Chapter 35. The Protein Structure Project, 1950–1959: First Concerted Effort of a Protein Structure Determination in the U.S.

A. Tulinsky, 1996 .

Structure of Ca2+ prothrombin fragment 1 including the conformation of the Gla domain.

A. Tulinsky, M. Soriano-garcia, E. Skrzypczak‐Jankun, 1989, Biochemistry.

Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.

R. St Charles, A. Tulinsky, E. Zhang, 1999, Journal of molecular biology.

The Na+ Binding Site of Thrombin (*)

E. Di Cera, A. Tulinsky, Y. Ayala, 1995, The Journal of Biological Chemistry.

Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.

A. Tulinsky, A Tulinsky, I. Mochalkin, 1999, Acta crystallographica. Section D, Biological crystallography.

The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.

A. Tulinsky, R. Arni, J. Geiger, 2002, Journal of molecular biology.

Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.

A. Tulinsky, R. Arni, K. Padmanabhan, 1994, Biochemistry.

Complete assignment of the aromatic proton magnetic resonance spectrum of the kringle 1 domain from human plasminogen: structure of the ligand-binding site.

M. Llinás, A. Tulinsky, A. Motta, 1987, Biochemistry.

Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.

M. Schenone, A. Tulinsky, F. Castellino, 2001, Journal of molecular biology.

Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen.

A. Tulinsky, F. Castellino, I. Mochalkin, 1998, Biochemistry.

An X-ray crystallographic investigation of exchange of localized sulfate ions in crystals of α-chymotrypsin

L. H. Wright, A. Tulinsky, 1973 .

Structure of tick anticoagulant peptide at 1.6 Å resolution complexed with bovine pancreatic trypsin inhibitor

A. Tulinsky, K. Padmanabhan, R. S. Charles, 2008, Protein science : a publication of the Protein Society.

Impact of protein-protein contacts on the conformation of thrombin-bound hirudin studied by comparison with the nuclear magnetic resonance solution structure of hirudin(1-51).

R. Huber, K. Wüthrich, P. Güntert, 1992, Journal of molecular biology.

Redetermination of the structure of porphine.

A. Tulinsky, A Tulinsky, B M Chen, 1972, Journal of the American Chemical Society.

The Structures of Domains of Blood Proteins

A. Tulinsky, A Tulinsky, 1991, Thrombosis and Haemostasis.

The crystal and molecular structure of chloro-alpha,beta,gamma,delta-tetraphenylporphinatomanganese(III).

A. Tulinsky, B. M. Chen, 1977, Journal of the American Chemical Society.

THE CRYSTAL AND MOLECULAR STRUCTURE OF CHLORO-α,β,Γ,Δ-TETRAPHENYLPORPHINATOMANGANESE(III)

A. Tulinsky, B. M. Chen, 1977 .

Molecular dynamics simulation of bovine prothrombin fragment 1 in the presence of calcium ions.

T. Darden, L. Pedersen, P. Charifson, 1992, Biochemistry.

Solution conformations of the gamma-carboxyglutamic acid domain of bovine prothrombin fragment 1, residues 1-65.

T. Darden, L. Pedersen, P. Charifson, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1.

A. Tulinsky, E. Skrzypczak‐Jankun, T. Seshadri, 1994, Biochemistry.

Structure of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Pseudomonas putida.

L. Lebioda, A. Tulinsky, R. Arni, 2003, Acta crystallographica. Section D, Biological crystallography.

Basic beryllium acetate. III. Evidence for chemical bonding; assessment of accuracy

A. Tulinsky, 1959 .

Structure of prothrombin fragment 1 refined at 2.8 A resolution.

A. Tulinsky, E. Skrzypczak‐Jankun, C. Park, 1988, Journal of molecular biology.

The structure of α-chymotrypsin. I. The refinement of the heavy-atom isomorphous derivatives at 2.8 Å resolution

C. Morimoto, A. Tulinsky, R. Vandlen, 1973 .

Crystallographic structure of a peptidyl keto acid inhibitor and human α-thrombin

M. Abelman, A. Tulinsky, K. Håkansson, 1995 .

THE STRUCTURE OF FREE BASE PORPHINE: AN AVERAGE OF THREE INDEPENDENT STRUCTURES *

A. Tulinsky, 1973, Annals of the New York Academy of Sciences.

Automatic crystal alignment and intensity data collection with a computer controlled diffractometer

A. Tulinsky, R. Vandlen, 1971 .

Comparison of the independent solvent structures of dimeric alpha-chymotrypsin with themselves and with gamma-chymotrypsin.

A. Tulinsky, R A Blevins, A Tulinsky, 1985, The Journal of biological chemistry.

The molecular environment of the Na+ binding site of thrombin.

A. Tulinsky, E. Zhang, A Tulinsky, 1997, Biophysical chemistry.

Conformational rearrangements required of the V3 loop of HIV‐1 gp120 for proteolytic cleavage and infection

Michael E. Johnson, A. Tulinsky, K. Padmanabhan, 1994, FEBS letters.

The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution.

A. Tulinsky, R A Blevins, A Tulinsky, 1985, The Journal of biological chemistry.

Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution.

A. Tulinsky, R. Blevins, 1987, The Journal of biological chemistry.

Peptide mimetics of the thrombin-bound structure of fibrinopeptide A.

M Kahn, A. Tulinsky, S. Bertenshaw, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.

A. Tulinsky, K. Håkansson, R. Arni, 1998, Biochemistry.

Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties.

R. Nutt, S. Tamura, A. Tulinsky, 1996, Journal of medicinal chemistry.

The structure of α‐chymotrypsin. II. Fourier phase refinement and extension of the dimeric structure at 1.8 Å resolution by density modification

A. Tulinsky, N. Raghavan, 1979 .

Novel thrombin inhibitors that are based on a macrocyclic tripeptide motif

A. Tulinsky, B. Maryanoff, Joan M. Lewis, 1996 .

Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.

A. Tulinsky, J. Sadler, R. Krishnan, 2000, Acta crystallographica. Section D, Biological crystallography.

Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom.

A. Tulinsky, R. Arni, R. Ward, 1994, Acta crystallographica. Section D, Biological crystallography.

Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.

A. Tulinsky, J. Maraganore, J W Fenton, 1994, Biochemistry.

Localization of the Thrombin-binding Domain on Prothrombin Fragment 2*

A. Tulinsky, P. Liaw, R. Austin, 1998, The Journal of Biological Chemistry.

Transformation of the marine natural product cyclotheonamide A by aqueous base. X-ray analysis of a novel ligand complexed with human α-thrombin

A. Tulinsky, E. Zhang, B. Maryanoff, 1996 .

Synthesis, structure, and structure‐activity relationships of divalent thrombin inhibitors containing an α‐keto‐amide transition‐state mimetic

A. Tulinsky, W. Ripka, T. Brunck, 1996, Protein science : a publication of the Protein Society.

The crystal and molecular structure of 2-desylidene-1,3-dithiolane

A. Tulinsky, William H. Schmidt, 1967 .

Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance.

O. Klezovitch, A. Tulinsky, A. Scanu, 1999, Biochemistry.

Crystallization of ribonuclease T1.

A. Tulinsky, P. Martin, F. Walz, 1980, Journal of molecular biology.

The structure of thujic acid: 7,7 dimethylcycloheptatriene-3-carboxylic acid

A. Tulinsky, R. Davis, 1962 .

Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.

A. Tulinsky, R. Arni, I. Mochalkin, 2000, Acta Crystallographica Section D: Biological Crystallography.

Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.

J H Matthews, R. St Charles, A. Tulinsky, 1999, Journal of medicinal chemistry.

STRUCTURAL CHANGES ACCOMPANYING EXPRESSION OF ENZYMIC FUNCTIONALITY: INTERACTION OF SMALL MOLECULES WITH α-CHYMOTRYPSIN

A. Tulinsky, 1981 .

The structure of recombinant plasminogen kringle 1 and the fibrin binding site.

A. Tulinsky, K. Padmanabhan, T. Wu, 1994 .

Structure of the lysine-fibrin binding subsite of human plasminogen kringle 4.

A. Tulinsky, A. Mulichak, 1990, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.