T. Cierpicki

发表

An Evolution-Based Approach to De Novo Protein Design and Case Study on Mycobacterium tuberculosis

Yang Zhang, Pralay Mitra, David Marsh, 2013, PLoS Comput. Biol..

Targeting protein–protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

Jolanta Grembecka, T. Cierpicki, J. Grembecka, 2015, Immunological reviews.

Design and synthesis of triarylacrylonitrile analogues of tamoxifen with improved binding selectivity to protein kinase C.

T. Cierpicki, C. Carpenter, R. Sorenson, 2016, Bioorganic & medicinal chemistry.

The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.

R. Kuick, K. Elenitoba-Johnson, N. Pinnell, 2015, Immunity.

Canonical protein inhibitors of serine proteases

J. Otlewski, T. Cierpicki, D. Krowarsch, 2003, Cellular and Molecular Life Sciences CMLS.

Amide proton temperature coefficients as hydrogen bond indicators in proteins

J. Otlewski, T. Cierpicki, 2001, Journal of biomolecular NMR.

Structure-function relationship of serine protease-protein inhibitor interaction.

J Otlewski, M. Jaskólski, J. Otlewski, 2001, Acta biochimica Polonica.

Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.

Rork Kuick, Sarah Caruso, Ivan Maillard, 2013, Cancer research.

Charged gels as orienting media for measurement of residual dipolar couplings in soluble and integral membrane proteins.

T. Cierpicki, J. Bushweller, 2004, Journal of the American Chemical Society.

Structure-based design of novel benzoxazinorifamycins with potent binding affinity to wild-type and rifampin-resistant mutant Mycobacterium tuberculosis RNA polymerases.

T. Cierpicki, N. Zhang, H. Showalter, 2012, Journal of medicinal chemistry.

H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor development.

T. Cierpicki, J. Grembecka, D. Rogawski, 2016, Future medicinal chemistry.

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

Craig W. Lindsley, Shaun R. Stauffer, Jolanta Grembecka, 2014, Journal of medicinal chemistry.

Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction.

T. Cierpicki, J. Grembecka, Łukasz Berlicki, 2020, European journal of medicinal chemistry.

Validation of approximate nonempirical scoring model for menin-mixed lineage leukemia inhibitors

T. Cierpicki, J. Grembecka, Wiktoria Jedwabny, 2018, Theoretical Chemistry Accounts.

Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes

T. Cierpicki, J. Grembecka, G. Lund, 2015, Journal of medicinal chemistry.

Synthesis of Triethyl N-Formyl-N-phosphonomethylglycinate and Diethyl N-Formyl-N-phosphonomethylglycine and Studies of Their Rotational Conformers by Dynamic NMR

T. Cierpicki, J. Grembecka, Z. Ziora, 1999 .

Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction

T. Cierpicki, J. Grembecka, G. Lund, 2014, ACS chemical biology.

Changing the Ap Evolutionary Pro

Design, Yang Zhang, Huang, 2019 .

Changing the Ap through Evolutio

Yang Zhang, Huang, Liu Liu, 2019 .

Structural features and chaperone activity of the NudC protein family.

K. Caldwell, T. Cierpicki, Z. Derewenda, 2011, Journal of molecular biology.

High resolution structure of the HDGF PWWP domain: A potential DNA binding domain

T. Cierpicki, J. Bushweller, J. Grembecka, 2006, Protein science : a publication of the Protein Society.

Targeting the MLL complex in castration resistant prostate cancer

S. Dhanasekaran, A. Chinnaiyan, A. Nesvizhskii, 2015, Nature Medicine.

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Dafydd G. Thomas, T. Cierpicki, J. Grembecka, 2016, Oncotarget.

3-Substituted-N-(4-Hydroxynaphthalen-1-yl)arylsulfonamides as a Novel Class of Selective Mcl-1 Inhibitors: Structure-Based Design, Synthesis, SAR, and Biological Evaluation

T. Cierpicki, Z. Nikolovska-Coleska, J. Stuckey, 2014, Journal of medicinal chemistry.

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

Jessica K. Gagnon, Chinmay Y. Majmudar, C. Brooks, 2012, Angewandte Chemie.

Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 (BCL6) BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design

Alexander D. MacKerell, A. Melnick, T. Cierpicki, 2019 .

Stabilizing the Mixed Lineage Leukemia Protein

T. Cierpicki, J. Grembecka, 2017, The New England journal of medicine.

The PAF Complex Regulation of Prmt5 Facilitates the Progression and Maintenance of MLL-Fusion Leukemia

Wei Chen, T. Cierpicki, J. Grembecka, 2017, Oncogene.

X-Ray Structure of a Calcium Activated TMEM16 Lipid Scramblase

Kristen I. Fread, G. Hummer, J. Hurley, 2015 .

Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity.

T. Cierpicki, Takeshi Corpora, L. Roudaia, 2010, Journal of molecular biology.

Supplemental Data Structural Basis for Recognition of SMRT / N-CoR by the MYND Domain and its Contribution to AML 1 / ETO ’ s Activity

J. Gaudet, T. Cierpicki, L. Roudaia, 2007 .

Letter to the Editor: Assignment of 1H, 13C and 15N resonances of the N-terminal microtubule-binding domain of human doublecortin

J. Otlewski, T. Cierpicki, J. Bushweller, 2003, Journal of biomolecular NMR.

Column Chromatography and Preparative TLC for Isolation and Purification of Coumarins from Peucedanum verticillare L. Koch ex DC

T. Cierpicki, K. Głowniak, J. Kulesza, 2005, JPC – Journal of Planar Chromatography – Modern TLC.

Hydrogen bonds in human ubiquitin reflected in temperature coefficients of amide protons.

J. Otlewski, T. Cierpicki, I. Zhukov, 2002, Journal of magnetic resonance.

Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods.

H. Carlson, T. Cierpicki, Phani Ghanakota, 2021, Bioorganic & medicinal chemistry.

The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity.

T. Cierpicki, J. Grembecka, P. Kafarski, 2003, Journal of medicinal chemistry.

Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase

T. Cierpicki, J. Grembecka, P. Kafarski, 2002 .

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.

Jolanta Grembecka, Thomas Hartley, J. Hess, 2012, Nature chemical biology.

Theoretical models of inhibitory activity for inhibitors of protein–protein interactions: targeting menin–mixed lineage leukemia with small molecules

T. Cierpicki, J. Grembecka, S. Kłossowski, 2017, MedChemComm.

Degradation of Amino-(3-methoxyphenyl)methanephosphonic Acid by Alternaria sp

T. Cierpicki, J. Lipok, P. Kafarski, 2002 .

Hydrolysis of the Phosphonamidate Bond in Phosphono Dipeptide Analogues - The Influence of the Nature of the N-Terminal Functional Group

T. Cierpicki, J. Grembecka, P. Kafarski, 2003 .

Dysregulated hematopoiesis caused by mammary cancer is associated with epigenetic changes and hox gene expression in hematopoietic cells.

B. Nelson, T. Cierpicki, J. Grembecka, 2013, Cancer research.

Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes

Katherine A. Gallagher, J. Westwick, T. Cierpicki, 2013, PloS one.

NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor‐1 (AMCI‐1): Structural similarity with Ascaris protease inhibitors

J. Otlewski, T. Cierpicki, J. Bania, 2000, Protein science : a publication of the Protein Society.

MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression

N. Zeleznik-Le, Z. Xia, M. Diaz, 2008, Proceedings of the National Academy of Sciences.

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization

F. Gray, T. Cierpicki, J. Grembecka, 2016, Nature Communications.

Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.

J. Gaudet, T. Cierpicki, L. Roudaia, 2007, Cancer cell.

Targeting epigenetic protein-protein interactions with small-molecule inhibitors.

T. Cierpicki, J. Grembecka, B. Linhares, 2020, Future medicinal chemistry.

GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode.

T. Cierpicki, J. Grembecka, H. Cho, 2018, ACS chemical biology.

Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

N. Zeleznik-Le, D. Shultis, T. Cierpicki, 2010, Nature Structural &Molecular Biology.

Molecular Basis of the Mixed Lineage Leukemia-Menin Interaction

Jolanta Grembecka, Thomas Hartley, T. Cierpicki, 2010, The Journal of Biological Chemistry.

Development of potent dimeric inhibitors of GAS41 YEATS domain.

V. Keshamouni, T. Cierpicki, J. Grembecka, 2021, Cell chemical biology.

Increased slow dynamics defines ligandability of BTB domains

T. Cierpicki, J. Grembecka, Mariusz Jaremko, 2022, Nature Communications.

Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer

T. Cierpicki, J. Grembecka, Dakang Xu, 2021, Science Advances.

Small molecule inhibitors targeting Polycomb Repressive Complex 1 RING domain

P. González-Alonso, F. Gray, T. Cierpicki, 2021, Nature Chemical Biology.

Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.

Alexander D. MacKerell, O. Elemento, J. Leonard, 2016, The Journal of clinical investigation.

EWS-FLI1 and Menin Converge to Regulate ATF4 Activity in Ewing Sarcoma

Z. Nwosu, T. Cierpicki, J. Grembecka, 2021, Molecular Cancer Research.

Menin regulates the serine biosynthetic pathway in Ewing sarcoma

Dafydd G. Thomas, Ho-Joon Lee, T. Cierpicki, 2018, The Journal of pathology.

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations.

T. Cierpicki, J. Grembecka, S. Kłossowski, 2020, Blood.

Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.

T. Cierpicki, J. Grembecka, S. Kłossowski, 2018, Journal of medicinal chemistry.

Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.

Bo Wen, Jolanta Grembecka, Hongzhi Miao, 2015, Cancer cell.

Challenges and opportunities in targeting the menin-MLL interaction.

Jolanta Grembecka, T. Cierpicki, J. Grembecka, 2014, Future medicinal chemistry.

Challenges and opportunities in targeting the

T. Cierpicki, J. Grembecka, 2014 .

Challenges and opportunities in targeting the menin-MLL interaction.

T. Cierpicki, J. Grembecka, 2014, Future medicinal chemistry.

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Tao Zhang, Jeanne A. Stuckey, Chenzhong Liao, 2013, Molecular Cancer Therapeutics.

- 1-A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In vitro and In vivo

A. Azmi, Tao Zhang, R. Mohammad, 2013 .

The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.

J. Hess, T. Cierpicki, J. Grembecka, 2014, Blood.

Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.

Alexander D. MacKerell, A. Melnick, T. Cierpicki, 2018, Journal of medicinal chemistry.

Epigenetic regulation of IL‐12‐dependent T cell proliferation

Y. Dou, T. Cierpicki, J. Grembecka, 2015, Journal of leukocyte biology.

Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein*

T. Cierpicki, J. Grembecka, M. Chruszcz, 2011, The Journal of Biological Chemistry.

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia.

Maksymilian Chruszcz, Jolanta Grembecka, Thomas Hartley, 2012, Blood.

NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.

J. Beckwith, T. Cierpicki, Yunpeng Zhou, 2008, Molecular cell.

Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

Charles R. Schmidt, John H. Bushweller, T. Cierpicki, 2013, Structure.

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development.

J. D. Engel, R. Kuick, N. Pinnell, 2018, Blood.

Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

G. Pfeifer, T. Cierpicki, J. Grembecka, 2022, Cancer discovery.

Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma

T. Cierpicki, J. Grembecka, S. Kłossowski, 2017, Molecular Cancer Therapeutics.

Covalent inhibition of NSD1 histone methyltransferase

A. Ferrando, M. Sulis, P. González-Alonso, 2020, Nature Chemical Biology.

Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility.

C. Lindsley, T. Cierpicki, J. Grembecka, 2015, Bioorganic & medicinal chemistry letters.

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.

S. Malek, Y. Dou, T. Cierpicki, 2015, The Journal of clinical investigation.

Ash 1 l controls quiescence and self-renewal potential in hematopoietic stem cells

S. Malek, Y. Dou, T. Cierpicki, 2015 .

Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.

M. Low, T. Giordano, N. Wright, 2017, Gastroenterology.

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.

O. Abdel-Wahab, Y. Dou, T. Cierpicki, 2019, The Journal of clinical investigation.

The DCX-domain tandems of doublecortin and doublecortin-like kinase

C. Walsh, J. Otlewski, Z. Dauter, 2003, Nature Structural Biology.

Importance of α–helix N–capping motif in stabilization of ββα fold

Jacek Otlewski, J. Otlewski, T. Cierpicki, 2003 .

Importance of (cid:1) -helix N-capping motif in stabilization of (cid:2)(cid:2)(cid:1) fold

J. Otlewski, T. Cierpicki, K. Kościelska-Kasprzak, 2003 .

Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.

T. Cierpicki, J. Bushweller, N. Speck, 2009, Blood.

Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML with activating FLT3 mutations.

T. Cierpicki, J. Grembecka, S. Kłossowski, 2020, Blood.

Solution NMR studies reveal no global flexibility in the catalytic domain of CDC25B

T. Cierpicki, G. Lund, 2014, Proteins.

The binding of the PDZ tandem of syntenin to target proteins.

Jolanta Grembecka, Zygmunt S Derewenda, T. Cierpicki, 2006, Biochemistry.

Probing the supramodular architecture of a multidomain protein: the structure of syntenin in solution.

T. Cierpicki, J. Bushweller, Z. Derewenda, 2005, Structure.

Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover

T. Cierpicki, J. Merchant, J. Grembecka, 2022, bioRxiv.

2-Aminobenzothiazoles in anticancer drug design and discovery.

T. Cierpicki, J. Grembecka, Guang Huang, 2023, Bioorganic chemistry.

Profiling the dynamic interfaces of fluorinated transcription complexes for ligand discovery and characterization.

T. Cierpicki, A. Mapp, Ningkun Wang, 2012, ACS chemical biology.

Review Canonical protein inhibitors of serine proteases

J. Otlewski, T. Cierpicki, D. Krowarsch, 2003 .

NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.

Jacek Otlewski, J. Otlewski, T. Cierpicki, 2002, Journal of molecular biology.

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

F. Cao, Yong Chen, M. Lei, 2010, PloS one.

The DC‐module of doublecortin: Dynamics, domain boundaries, and functional implications

T. Cierpicki, J. Bushweller, Z. Derewenda, 2006, Proteins.

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL).

T. Cierpicki, J. Grembecka, Ting Zhao, 2016, Journal of medicinal chemistry.

The same site on LEDGF IBD domain represents therapeutic target for MLL leukemia and HIV

J. Hess, T. Cierpicki, J. Grembecka, 2014 .

leukemia and HIV The same site on LEDGF IBD domain represents therapeutic target for MLL

T. Cierpicki, J. Grembecka, Marcelo J. Murai, 2014 .

Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase.

T. Cierpicki, J. Grembecka, H. Cho, 2015, Biochemistry.

Unexpected specificity within dynamic transcriptional protein–protein complexes

C. Fierke, T. Cierpicki, A. Mapp, 2020, Proceedings of the National Academy of Sciences.

Unexpected Specificity within Dynamic Transcriptional Protein-Protein Complexes

C. Fierke, T. Cierpicki, A. Mapp, 2020, bioRxiv.

Synthesis, conformation, and immunosuppressive activity of CLX and its analogues

M. Lisowski, T. Cierpicki, I. Siemion, 2003, Biopolymers.

Zmiz 1-Notch 1 interaction in preT cells 1 Stage-specific roles for Zmiz 1 in Notch-dependent steps of early T-cell development

J. D. Engel, R. Kuick, N. Pinnell, 2018 .

Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner

S. Malek, T. Cierpicki, J. Grembecka, 2016, Leukemia.

Abstract 3225: LEDGF IBD domain represents therapeutic target for MLL leukemia and HIV

J. Hess, T. Cierpicki, J. Grembecka, 2014 .

The dimerization mechanism of LIS1 and its implication for proteins containing the LisH motif.

J. Otlewski, T. Cierpicki, Z. Derewenda, 2006, Journal of molecular biology.

Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma.

T. Cierpicki, J. Grembecka, D. Lombard, 2019, Cancer discovery.

Molecular Basis of Menin-MLL Interaction: Implication for Targeted Therapies in MLL Leukemias.

T. Cierpicki, J. Grembecka, Amalia M Belcher, 2009 .

Changing the Apoptosis Pathway through Evolutionary Protein Design.

Pralay Mitra, Yang Zhang, Christoph H. Borchers, 2019, Journal of molecular biology.

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

T. Cierpicki, J. Bushweller, Z. Derewenda, 2009, BMC Structural Biology.

A lipopeptidomimetic of transcriptional activation domains selectively disrupts Med25 PPIs

S. Merajver, T. Cierpicki, A. Mapp, 2023, bioRxiv.

Progress towards small molecule inhibitors of the Menin-Mixed Lineage Leukemia (MLL) interaction with in vivo utility

C. Lindsley, T. Cierpicki, J. Grembecka, 2015 .

The solution structure and dynamics of the DH‐PH module of PDZRhoGEF in isolation and in complex with nucleotide‐free RhoA

D. Svergun, T. Cierpicki, J. Bushweller, 2009, Protein science : a publication of the Protein Society.

Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators

C. Brooks, C. Fierke, T. Cierpicki, 2018, Proceedings of the National Academy of Sciences.

Determination of a high precision structure of a novel protein, Linum usitatissimum trypsin inhibitor (LUTI), using computer-aided assignment of NOESY cross-peaks.

J Otlewski, J. Otlewski, T. Cierpicki, 2000, Journal of molecular biology.

Abstract 2917: Design, synthesis and biological evaluation of two chemical classes as novel small molecule Mcl-1 inhibitors

A. Azmi, R. Mohammad, T. Cierpicki, 2012 .

Applications of oxetanes in drug discovery and medicinal chemistry.

T. Cierpicki, J. Grembecka, Guang Huang, 2023, European journal of medicinal chemistry.

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

Y. Dou, T. Cierpicki, J. Grembecka, 2021, Nature Communications.

Increasing the accuracy of solution NMR structures of membrane proteins by application of residual dipolar couplings. High-resolution structure of outer membrane protein A.

T. Cierpicki, J. Bushweller, L. Tamm, 2006, Journal of the American Chemical Society.

Structural features and chaperone activity of the NudC protein family.

T. Cierpicki, Z. Derewenda, P. Stukenberg, 2011, Journal of molecular biology.

Molecular Basis of the Mixed Lineage Leukemia-Menin Interaction

T. Cierpicki, J. Grembecka, Amalia M Belcher, 2010, The Journal of Biological Chemistry.

Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.

T. Cierpicki, J. Bushweller, Stephanie A. Johnson, 2013, Structure.

Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300.

Jessica K. Gagnon, Chinmay Y. Majmudar, C. Brooks, 2012, Angewandte Chemie.

The solution structure and dynamics of the DH‐PH module of PDZRhoGEF in isolation and in complex with nucleotide‐free RhoA

D. Svergun, T. Cierpicki, J. Bushweller, 2009, Protein science : a publication of the Protein Society.

Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells.

M. Low, T. Giordano, N. Wright, 2017, Gastroenterology.

Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.

R. Kuick, T. Cierpicki, I. Maillard, 2013, Cancer research.

Thioamides in medicinal chemistry and as small molecule therapeutic agents.

T. Cierpicki, J. Grembecka, Guang Huang, 2024, European journal of medicinal chemistry.

Menin in complex with MI-3454

Y. Dou, T. Cierpicki, J. Grembecka, 2020 .