G. Fernández-Ballester

发表

Computer-aided design of a PDZ domain to recognize new target sequences

V. Rybin, L. Serrano, M. Schwab, 2002, Nature Structural Biology.

Novel BRAFI599Ins Mutation Identified in a Follicular Variant of a Papillary Thyroid Carcinoma: A Molecular Modeling Approach.

J. Ramos, G. Fernández-Ballester, M. Cañadas-Garre, 2014, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

Control of Drosophila Gastrulation by Apical Localization of Adherens Junctions and RhoGEF2

Maria Leptin, M. Leptin, G. Fernández-Ballester, 2007, Science.

A synthetic hexapeptide (Argireline) with antiwrinkle activity.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2002, International journal of cosmetic science.

Molecular Modeling of the Full-length Human TRPV1 Channel in Closed and Desensitized States

G. Fernández-Ballester, A. Ferrer-Montiel, G. Fernández-Ballester, 2008, Journal of Membrane Biology.

Mechanisms of Blockade of the Muscle-Type Nicotinic Receptor by Benzocaine, a Permanently Uncharged Local Anesthetic

J. González-Ros, G. Fernández-Ballester, Raúl Cobo, 2020, Neuroscience.

Mechanisms Underlying the Strong Inhibition of Muscle-Type Nicotinic Receptors by Tetracaine

J. González-Ros, G. Fernández-Ballester, Raúl Cobo, 2018, Front. Mol. Neurosci..

Molecular Compatibility of the Channel Gate and the N Terminus of S5 Segment for Voltage-gated Channel Activity*

S. Ferroni, G. Fernández-Ballester, A. Ferrer-Montiel, 2005, Journal of Biological Chemistry.

Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2020, Expert opinion on therapeutic targets.

β–Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, International journal of molecular sciences.

Interaction of the Nicotinic Acetylcholine Receptor with Ligands and Membrane Lipids Studied by Fourier-Transform Infrared Spectroscopy and Photoaffinity Labeling

J. González-Ros, Asia M. Fernández, G. Fernández-Ballester, 1992 .

In silico approach for the discovery of new PPARγ modulators among plant-derived polyphenols

J. Encinar, G. Fernández-Ballester, V. Micol, 2015, Drug design, development and therapy.

Small peptides patterned after the N‐terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2003, Journal of neurochemistry.

TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Frontiers in molecular neuroscience.

Androgenic TRPM8 activity drives sexual dimorphism in a murine model of chronic migraine

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2021 .

Changes in inorganic and organic solutes in citrus growing under saline stresses

G. Fernández-Ballester, V. Martínez, A. Cerdá, 1998 .

ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Pharmacology & therapeutics.

Membrane‐tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity

J. González-Ros, C. Belmonte, G. Fernández-Ballester, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Adoption of beta structure by the inactivating "ball" peptide of the Shaker B potassium channel.

J. González-Ros, G. Fernández-Ballester, J. Albar, 1995, Biophysical journal.

Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain

E. Balazs, C. Belmonte, G. Fernández-Ballester, 2015, Nature Communications.

Muscle-Type Nicotinic Receptor Modulation by 2,6-Dimethylaniline, a Molecule Resembling the Hydrophobic Moiety of Lidocaine

J. González-Ros, G. Fernández-Ballester, Armando Alberola-Die, 2016, Front. Mol. Neurosci..

Comprehensive Survey of Consensus Docking for High-Throughput Virtual Screening

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Molecules.

Role of calcium in short-term responses of bean plants to osmotic or saline shocks

G. Fernández-Ballester, V. Martínez, A. Cerdá, 1997 .

Tolerance of citrus rootstock seedlings to saline stress based on their ability to regulate ion uptake and transport.

G. Fernández-Ballester, V. Martínez, F. García-Sánchez, 2003, Tree physiology.

Time course of solute accumulation and water relations in muskmelon plants exposed to salt during different growth stages

G. Fernández-Ballester, V. Martínez, M. Carvajal, 1998 .

Protein stability and interaction of the nicotinic acetylcholine receptor with cholinergic ligands studied by Fourier-transform infrared spectroscopy.

J. González-Ros, G. Fernández-Ballester, J. Castresana, 1992, The Biochemical journal.

TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Nature Communications.

A non-canonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression

G. Fernández-Ballester, A. Ferrer-Montiel, Ramón Martínez-Mármol, 2013, Journal of Cell Science.

Pharmacology of TRP Channels

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015 .

A role for cholesterol as a structural effector of the nicotinic acetylcholine receptor.

J. González-Ros, G. Fernández-Ballester, J. Castresana, 1994, Biochemistry.

In Silico Approaches for TRP Channel Modulation.

Magdalena Nikolaeva Koleva, Gregorio Fernandez-Ballester, G. Fernández-Ballester, 2019, Methods in molecular biology.

Thermal unfolding of the cytotoxin alpha-sarcin: phospholipid binding induces destabilization of the protein structure.

J. Gavilanes, G. Fernández-Ballester, J. Mancheño, 1995, Biochimica et biophysica acta.

Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies.

X. Xie, Yuanqiang Wang, G. Fernández-Ballester, 2019, ACS chemical neuroscience.

Identification of a Tetramerization Domain in the C Terminus of the Vanilloid Receptor

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2004, The Journal of Neuroscience.

Muscle-Type Nicotinic Receptor Blockade by Diethylamine, the Hydrophilic Moiety of Lidocaine

J. González-Ros, G. Fernández-Ballester, Armando Alberola-Die, 2016, Front. Mol. Neurosci..

Modulation of botulinum neurotoxin A catalytic domain stability by tyrosine phosphorylation

G. Fernández-Ballester, A. Ferrer-Montiel, C. Blanes-Mira, 2004, FEBS letters.

Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2001, Biochemistry.

Influence of C-terminal protein domains and protein-lipid interactions on tetramerization and stability of the potassium channel KcsA.

J. González-Ros, J. Encinar, G. Fernández-Ballester, 2004, Biochemistry.

Identification of SNARE complex modulators that inhibit exocytosis from an alpha-helix-constrained combinatorial library.

E. Pérez-Payá, G. Fernández-Ballester, A. Ferrer-Montiel, 2003, The Biochemical journal.

Conformational buffering underlies functional selection in intrinsically disordered protein regions

R. Pappu, Juan Cortés, G. Fernández-Ballester, 2021, Nature Structural & Molecular Biology.

High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations.

L. Serrano, G. Fernández-Ballester, M. Sobrinho-Simões, 2007, The Journal of clinical endocrinology and metabolism.

The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating.

Beiying Liu, F. Qin, G. Fernández-Ballester, 2015, Biophysical journal.

Progress in the Structural Basis of thermoTRP Channel Polymodal Gating

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2023, International journal of molecular sciences.

Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation

J. González-Ros, G. Fernández-Ballester, A. Ferrer-Montiel, 2014, The Journal of general physiology.

Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I

C. Belmonte, G. Fernández-Ballester, A. Fernández-Carvajal, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2020, Expert opinion on investigational drugs.

TRP channels interaction with lipids and its implications in disease.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015, Biochimica et biophysica acta.

Advances in modulating thermosensory TRP channels

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2012, Expert opinion on therapeutic patents.

Ionic Channels as Targets for Drug Design: A Review on Computational Methods

Antonio Ferrer-Montiel, J. González-Ros, G. Fernández-Ballester, 2011, Pharmaceutics.

New approaches to high‐throughput structure characterization of SH3 complexes: The example of Myosin‐3 and Myosin‐5 SH3 domains from S. cerevisiae

L. Serrano, A. Pastore, G. Fernández-Ballester, 2006, Protein science : a publication of the Protein Society.

Estrogen destabilizes microtubules through an ion‐conductivity‐independent TRPV1 pathway

G. Fernández-Ballester, A. Ferrer-Montiel, C. Goswami, 2011, Journal of neurochemistry.

Interaction of the human somatostatin receptor 3 with the multiple PDZ domain protein MUPP1 enables somatostatin to control permeability of epithelial tight junctions

S. Schulz, G. Fernández-Ballester, C. Liew, 2009, FEBS letters.

Labeling of the nicotinic acetylcholine receptor by a photoactivatable steroid probe: effects of cholesterol and cholinergic ligands.

J. González-Ros, G. Fernández-Ballester, A. Fernández, 1993, Biochimica et biophysica acta.

Role of the transient receptor potential vanilloid 1 in inflammation and sepsis

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2011, Journal of inflammation research.

Lipid modulation of ion channels through specific binding sites.

J. A. Encinar, J. González-Ros, J. Encinar, 2014, Biochimica et biophysica acta.

New Strategies to Develop Novel Pain Therapies: Addressing Thermoreceptors from Different Points of View

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2011, Pharmaceuticals.

Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels

G. Fernández-Ballester, A. Ferrer-Montiel, F. Viana, 2009, Molecular pain.

Uptake, Transport, and Concentration of Chloride and Sodium in Three Citrus Rootstock Seedlings

G. Fernández-Ballester, F. García-Sánchez, P. Botía, 2005 .

The histidine-phosphocarrier protein of Streptomyces coelicolor folds by a partially folded species at low pH.

G. Fernández-Ballester, J. Neira, F. Titgemeyer, 2003, European journal of biochemistry.

Dynamics of tryptophan in the histidine-containing phosphocarrier protein of Streptomyces coelicolor: evidence of multistate equilibrium unfolding.

M. Prieto, G. Fernández-Ballester, J. Neira, 2007, Biochemistry.

Biophysical characterization of the enzyme I of the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system.

H. Nothaft, G. Fernández-Ballester, J. Neira, 2006, Biophysical journal.

Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity

G. Fernández-Ballester, I. Gomez-Monterrey, M. Bonache, 2021, International journal of molecular sciences.

Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity

G. Fernández-Ballester, M. Bonache, A. Fernández-Carvajal, 2020, Scientific Reports.

The calmodulin‐binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3

G. Fernández-Ballester, A. Ferrer-Montiel, M. Tamkun, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of cholesterol as a structural and functional effector of the nicotinic acetylcholine receptor.

J. González-Ros, G. Fernández-Ballester, J. Castresana, 1994, Biochemical Society transactions.

A Role of the Transient Receptor Potential Domain of Vanilloid Receptor I in Channel Gating

C. Belmonte, G. Fernández-Ballester, A. Fernández-Carvajal, 2007, The Journal of Neuroscience.

Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic Receptors

J. González-Ros, J. Encinar, G. Fernández-Ballester, 2021, International journal of molecular sciences.

Stabilization of TRAIL, an all-beta-sheet multimeric protein, using computational redesign.

L. Serrano, W. Quax, G. Fernández-Ballester, 2004, Protein engineering, design & selection : PEDS.

Molecular architecture of the vanilloid receptor. Insights for drug design.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2004, European journal of biochemistry.

Design and validation of neuronal exocytosis blocking peptides as potential novel antiperspirants

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2023, Experimental dermatology.

ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs

José A. Encinar, G. Fernandez-Ballester, Ignacio E. Sánchez, 2009, Bioinform..

Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila Crumbs for the PDZ domains of Stardust and DmPar-6.

Gregorio Fernandez-Ballester, Luis Serrano, L. Serrano, 2006, European journal of cell biology.

Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability.

J. González-Ros, J. Encinar, G. Fernández-Ballester, 2012, Biochemistry.

Protein structural effects of agonist binding to the nicotinic acetylcholine receptor

J. González-Ros, G. Fernández-Ballester, J. Castresana, 1992, FEBS letters.

Ligand screening by exoproteolysis and mass spectrometry in combination with computer modelling.

Enrique Querol, Francesc X Aviles, Josep Villanueva, 2003, Journal of molecular biology.

The tryptophan switch: changing ligand-binding specificity from type I to type II in SH3 domains.

Gregorio Fernandez-Ballester, Luis Serrano, L. Serrano, 2004, Journal of molecular biology.

Prediction of protein-protein interaction based on structure.

Luis Serrano, Gregorio Fernandez-Ballester, L. Serrano, 2006, Methods in molecular biology.

Molecular Binding Mechanism of TtgR Repressor to Antibiotics and Antimicrobials

Gregorio Fernandez-Ballester, Bertrand Morel, J. Ramos, 2015, PloS one.

The Region Adjacent to the C-end of the Inner Gate in Transient Receptor Potential Melastatin 8 (TRPM8) Channels Plays a Central Role in Allosteric Channel Activation*

Y. Korchev, G. Fernández-Ballester, A. Ferrer-Montiel, 2014, The Journal of Biological Chemistry.

ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2022, Pharmacology & therapeutics.

Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.

A. Valencia, P. Beltrão, Luis Serrano, 2009, Journal of Molecular Biology.

Advances in modulating thermosensory TRP channels

J. González-Ros, G. Fernández-Ballester, A. Fernández-Carvajal, 2012, Expert opinion on therapeutic patents.

TRP channels interaction with lipids and its implications in disease.

G. Fernández-Ballester, A. Fernández-Carvajal, A. Ferrer-Montiel, 2015, Biochimica et biophysica acta.

N-type Inactivation of the Potassium Channel KcsA by the Shaker B “Ball” Peptide

J. González-Ros, G. Fernández-Ballester, F. Gavilanes, 2008, Journal of Biological Chemistry.

Competing Lipid-Protein and Protein-Protein Interactions Determine Clustering and Gating Patterns in the Potassium Channel from Streptomyces lividans (KcsA)*

J. González-Ros, G. Fernández-Ballester, J. A. Poveda, 2015, The Journal of Biological Chemistry.

Modulation of clustering and gating in KcsA 1 Competing Lipid-Protein and Protein-Protein Interactions Determine Clustering and Gating Patterns in KcsA *

J. González-Ros, J. Encinar, G. Fernández-Ballester, 2015 .

Occupancy of nonannular lipid binding sites on KcsA greatly increases the stability of the tetrameric protein.

J. González-Ros, J. Encinar, D. Otzen, 2010, Biochemistry.