M. Akeson

发表

Real-Time Culture-Independent Microbial Profiling Onboard the International Space Station Using Nanopore Sequencing

Kristen K. John, Serena M. Auñón-Chancellor, D. Turner, 2021, Genes.

Error rates for nanopore discrimination among cytosine, methylcytosine, and hydroxymethylcytosine along individual DNA strands

Mark Akeson, Kevin Karplus, Jacob Schreiber, 2013, Proceedings of the National Academy of Sciences.

The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

Hugh E. Olsen, B. Paten, Miten Jain, 2016, Genome Biology.

Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel

Hugh E. Olsen, D. Haussler, D. Deamer, 2001, Nature Biotechnology.

Distinct Complexes of DNA Polymerase I (Klenow Fragment) for Base and Sugar Discrimination during Nucleotide Substrate Selection*

Daniel R. Garalde, K. Lieberman, M. Akeson, 2011, The Journal of Biological Chemistry.

Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase.

K. Lieberman, M. Akeson, G. M. Cherf, 2010, Journal of the American Chemical Society.

Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore.

K. Lieberman, M. Akeson, Hongyun Wang, 2009, Journal of the American Chemical Society.

Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution.

Daniel R. Garalde, K. Lieberman, M. Akeson, 2009, ACS nano.

Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore.

D. Deamer, W. Dunbar, K. Lieberman, 2007, Nature nanotechnology.

Nanopore cheminformatics.

M. Akeson, S. Winters-Hilt, 2004, DNA and cell biology.

Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules.

J. T. Rodgers, Hugh E. Olsen, D. Deamer, 2003, Nucleic acids research.

Biosensors for DNA sequence detection.

M. Akeson, W. Vercoutere, 2002, Current opinion in chemical biology.

Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules.

D. Branton, D. Deamer, M. Akeson, 1999, Biophysical journal.

Three decades of nanopore sequencing

D. Branton, D. Deamer, M. Akeson, 2016, Nature Biotechnology.

Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells

Hugh E. Olsen, C. Vollmers, R. DuBois, 2017, Nature Communications.

Nanopore native RNA sequencing of a human poly(A) transcriptome

Angela N. Brooks, Hugh E. Olsen, N. Loman, 2018, bioRxiv.

Mapping DNA Methylation with High Throughput Nanopore Sequencing

Jordan M. Eizenga, Hugh E. Olsen, B. Paten, 2017, Nature Methods.

Nanopores and nucleic acids: prospects for ultrarapid sequencing.

D. Deamer, M. Akeson, D W Deamer, 2000, Trends in biotechnology.

Replication of Individual DNA Molecules under Electronic Control Using a Protein Nanopore

Mark Akeson, David W. Deamer, D. Deamer, 2010, Nature nanotechnology.

Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes

Sergey Koren, David Haussler, Joel Armstrong, 2020, Nature Biotechnology.

Electronic control of DNA polymerase binding and unbinding to single DNA molecules.

Mark Akeson, Robin Abu-Shumays, William B Dunbar, 2009, ACS nano.

Nanopore Long-Read RNAseq Reveals Widespread Transcriptional Variation Among the Surface Receptors of Individual B cells

Mark Akeson, Charles Cole, E. Camilla Forsberg, 2017 .

Cytosine Variant Calling with High-throughput Nanopore Sequencing

Benedict Paten, Mark Akeson, Jordan M. Eizenga, 2016, bioRxiv.

Nanopore ReCappable sequencing maps SARS-CoV-2 5′ capping sites and provides new insights into the structure of sgRNAs

Hugh E. Olsen, E. Birney, L. Ettwiller, 2021, bioRxiv.

Linear Assembly of a Human Y Centromere using Nanopore Long Reads

Karen H. Miga, Hugh E. Olsen, D. Haussler, 2017, bioRxiv.

Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

Hugh E. Olsen, M. Diekhans, L. Ettwiller, 2020, bioRxiv.

miRNA-independent function of long noncoding pri-miRNA loci

J. Costello, D. Lim, Daniel He, 2021, Proceedings of the National Academy of Sciences.

Identification of high-confidence human poly(A) RNA isoform scaffolds using nanopore sequencing

Hugh E. Olsen, M. Diekhans, L. Ettwiller, 2021, RNA.

An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.

R. Jensen, M. Akeson, J. Battey, 1999, Biochemistry.

The Gastrin-releasing Peptide Receptor Is Rapidly Phosphorylated by a Kinase Other Than Protein Kinase C After Exposure to Agonist (*)

J. Battey, R. Jensen, R. Benya, 1995, The Journal of Biological Chemistry.

Discovery of a High Affinity Radioligand for the Human Orphan Receptor, Bombesin Receptor Subtype 3, Which Demonstrates That It Has a Unique Pharmacology Compared with Other Mammalian Bombesin Receptors*

R. Jensen, R. Searles, M. Akeson, 1997, The Journal of Biological Chemistry.

CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma

Max A. Horlbeck, Brian V Lien, Hugh E. Olsen, 2019, Genome Biology.

Evidence that sensitivity to steroid anesthetics appears late in evolution

D. Deamer, M. Akeson, A. E. Oliver, 1991, Brain Research.

Soil Resource Inventory of Sequoia National Park, Central Part, California

M. Akeson, G. L. Huntington, 1987 .

Linear assembly of a human centromere on the Y chromosome

David Haussler, Benedict Paten, Mark Akeson, 2018, Nature Biotechnology.

In Vitro Analysis of Bombesin/Gastrin-Releasing Peptide Receptor (bb2) Ligand Binding and G-Protein Coupling

J. Battey, R. Jensen, M. Akeson, 1998 .

Steady-state catecholamine distribution in chromaffin granule preparations: a test of the pump-leak hypothesis of general anesthesia.

D. Deamer, M. Akeson, 1989, Biochemistry.

Adsorption of Al3+ to phosphatidylcholine vesicles.

M. Akeson, D. N. Munns, R. Burau, 1989, Biochimica et biophysica acta.

Mechanism of Ionic Current Blockades during Polymer Transport through Pores of Nanometer Dimensions

Hugh E. Olsen, D. Deamer, M. Akeson, 2002 .

Use of a Nanoscale Pore to Read Short Segments within Single Polynucleotide Molecules

Hugh E. Olsen, D. Deamer, M. Akeson, 2002 .

Effect of gastrin-releasing peptide receptor number on receptor affinity, coupling, degradation, and modulation.

R. Jensen, R. Benya, M. Akeson, 1997, Molecular pharmacology.

Pharmacology and cell biology of the bombesin receptor subtype 4 (BB4-R).

R. Jensen, M. Akeson, D. Coy, 1999, Biochemistry.

Advances in nanopore direct RNA sequencing

Hugh E. Olsen, Miten Jain, M. Akeson, 2022, Nature Methods.

Nanopores Discriminate among Five C5-Cytosine Variants in DNA

M. Akeson, Jacob Schreiber, Zachary L. Wescoe, 2014, Journal of the American Chemical Society.

Uptake of aluminum into root cytoplasm: Predicted rates for important solution complexes

M. Akeson, D. N. Munns, 1990 .

A community challenge to evaluate RNA-seq, fusion detection, and isoform quantification methods for cancer discovery.

Joshua M. Stuart, John D. Watson, B. Haas, 2021, Cell systems.

Evidence that plasma membrane electrical potential is required for vesicular stomatitis virus infection of MDCK cells: A study using fluorescence measurements through polycarbonate supports

M. Akeson, D. Neville, C. Sharp, 2004, The Journal of Membrane Biology.

Proton conductance by the gramicidin water wire. Model for proton conductance in the F1F0 ATPases?

D. Deamer, M. Akeson, David W. Deamer, 1991, Biophysical journal.

Dynamics of the translocation step measured in individual DNA polymerase complexes.

K. Lieberman, M. Akeson, Hongyun Wang, 2012, Journal of the American Chemical Society.

Direct Observation of Translocation in Individual DNA Polymerase Complexes*

Nahid N. Jetha, K. Lieberman, M. Akeson, 2012, The Journal of Biological Chemistry.

Feedback control of a DNA molecule tethered in a nanopore to repeatedly probe DNA-binding enzymes

W. Dunbar, K. Lieberman, M. Akeson, 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Fluoride matrix modifiers for the determination of aluminum by graphite furnace atomic absorption spectrometry

M. Akeson, E. Nater, R. Burau, 1989 .

Improved data analysis for the MinION nanopore sequencer

Benedict Paten, Mark Akeson, Ian T. Fiddes, 2015, Nature Methods.

Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing

Mark Akeson, Miten Jain, M. Akeson, 2019, PloS one.

Nanopore sensors for nucleic acid analysis

M. Akeson, A. Marziali, J. Nakane, 2003 .

Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes

Colleen M. Bosworth, Mitchell R. Vollger, Karen H. Miga, 2020, Nature Biotechnology.

Efficient de novo assembly of eleven human genomes using PromethION sequencing and a novel nanopore toolkit

Adam M. Phillippy, David Haussler, Joel Armstrong, 2019, bioRxiv.

Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2

Angela N. Brooks, Miten Jain, M. Akeson, 2021, eLife.

Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2

Angela N. Brooks, E. Wakeland, Miten Jain, 2020, bioRxiv.

New DNA sequencing methods.

M. Akeson, A. Marziali, M Akeson, 2001, Annual review of biomedical engineering.

Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice.

R. Jensen, M. Akeson, J. Battey, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Single-molecule analysis of DNA-protein complexes using nanopores

Mark Akeson, Amit Meller, Anatoly Kolomeisky, 2007, Nature Methods.

Automated Forward and Reverse Ratcheting of DNA in a Nanopore at Five Angstrom Precision1

Mark Akeson, Kevin Karplus, K. Karplus, 2012, Nature Biotechnology.

Nanopore ReCappable sequencing maps SARS-CoV-2 5′ capping sites and provides new insights into the structure of sgRNAs

Hugh E. Olsen, E. Birney, L. Ettwiller, 2021, bioRxiv.

Unfoldase-mediated protein translocation through an α-hemolysin nanopore

Mark Akeson, Jeff Nivala, M. Akeson, 2013, Nature Biotechnology.

Synthesis of modified nucleotide polymers by the poly(U) polymerase Cid1: application to direct RNA sequencing on nanopores

M. Ares, Miten Jain, M. Akeson, 2021, bioRxiv.

Highly accurate classification of Watson-Crick basepairs on termini of single DNA molecules.

David Haussler, Mark Akeson, David Deamer, 2003, Biophysical journal.

Discrimination among protein variants using an unfoldase-coupled nanopore.

M. Akeson, Jacob Schreiber, Jeff Nivala, 2014, ACS nano.

Evaluation of nanopores as candidates for electronic analyte detection

Andre Marziali, Mark Akeson, M. Akeson, 2002, Electrophoresis.

Direct Nanopore Sequencing of Individual Full Length tRNA Strands

Hugh E. Olsen, Miten Jain, M. Akeson, 2021, bioRxiv.

Four Amino Acid Residues Are Critical for High Affinity Binding of Neuromedin B to the Neuromedin B Receptor*

Mark Akeson, J. Battey, R. Jensen, 1998, The Journal of Biological Chemistry.

Reading canonical and modified nucleotides in 16S ribosomal RNA using nanopore direct RNA sequencing

Mark Akeson, Daniel R. Garalde, Miten Jain, 2017, bioRxiv.

Kinetic mechanism of translocation and dNTP binding in individual DNA polymerase complexes.

K. Lieberman, M. Akeson, Hongyun Wang, 2013, Journal of the American Chemical Society.

Off Earth Identification of Bacterial Populations Using 16S rDNA Nanopore Sequencing

Kristen K. John, D. Turner, B. Paten, 2020, Genes.

Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes.

R. Jensen, R. Benya, M. Akeson, 1994, Molecular pharmacology.

Cheminformatics methods for novel nanopore analysis of HIV DNA termini

Matthew Landry, Mark Akeson, Maria Tanase, 2006, BMC Bioinformatics.

A preliminary length factor for erosion on steep slopes in Guatemala and its use to evaluate “curvas a nivel”

M. Akeson, M. Singer, 1984 .

Capture, Unfolding, and Detection of Individual tRNA Molecules Using a Nanopore Device

M. Akeson, R. Abu-Shumays, D. L. Bernick, 2015, Front. Bioeng. Biotechnol..

Lipid bilayer permeation by neutral aluminum citrate and by three α-hydroxy carboxylic acids

M. Akeson, D. N. Munns, Mark A. Akeson, 1989 .

Erratum to: The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

Hugh E. Olsen, B. Paten, Miten Jain, 2016, Genome Biology.

The bombesin receptor subtype 4 is coupled to phospholipase C and has a unique pharmacology

M. Akeson, J. Battey, T. Katsuno, 1998 .

Identification of Four Amino Acids in the Gastrin-releasing Peptide Receptor That Are Required for High Affinity Agonist Binding*

R. Jensen, M. Akeson, J. Battey, 1997, The Journal of Biological Chemistry.

Author response to John Kasianowicz and Sergey Bezrukov

D. Branton, D. Deamer, M. Akeson, 2016, Nature Biotechnology.

Adaptation of Human Ribosomal RNA for Nanopore Sequencing of Canonical and Modified Nucleotides.

Hugh E. Olsen, Miten Jain, M. Akeson, 2021, Methods in molecular biology.

Sensitivity to Anesthesia by Pregnanolone Appears Late in Evolution a

D. Deamer, M. Akeson, A. E. Oliver, 1991, Annals of the New York Academy of Sciences.

O P I N I O N Open Access

Hugh E. Olsen, B. Paten, Miten Jain, 2022 .

CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma

Max A. Horlbeck, Brian V Lien, Hugh E. Olsen, 2020, Genome Biology.

Author Correction: Nanopore native RNA sequencing of a human poly(A) transcriptome

Angela N. Brooks, Hugh E. Olsen, N. Loman, 2019, Nature Methods.

Water transport by the bacterial channel alpha-hemolysin.

D. Deamer, M. Akeson, S. Paula, 1999, Biochimica et biophysica acta.

Stabilization of intercellular contacts in MDCK cells during Ca2+ deprivation. Selective effects of monocarboxylic acids on desmosomes.

P. Skehan, M. Akeson, E. Sainz, 1992, Journal of cell science.

Nanopore sensors for nucleic acid analysis

M. Akeson, J. Nakane, Jonathan J Nakane, 2003 .

Unfoldase-mediated protein translocation through an α-hemolysin nanopore

M. Akeson, Jeff Nivala, Douglas B Marks, 2013, Nature Biotechnology.

The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

Hugh E. Olsen, B. Paten, Miten Jain, 2016, Genome Biology.

Automated Forward and Reverse Ratcheting of DNA in a Nanopore at Five Angstrom Precision

K. Karplus, K. Lieberman, M. Akeson, 2012, Nature Biotechnology.