P. Van Bockstal

发表

Potential of Near-Infrared Chemical Imaging as Process Analytical Technology Tool for Continuous Freeze-Drying.

T. De Beer, C. Vervaet, I. Nopens, 2018, Analytical chemistry.

In-line near infrared spectroscopy during freeze-drying as a tool to measure efficiency of hydrogen bond formation between protein and sugar, predictive of protein storage stability.

Thomas De Beer, Sigrid Pieters, Wouter L J Hinrichs, 2015, International journal of pharmaceutics.

In-line monitoring of compaction properties on a rotary tablet press during tablet manufacturing of hot-melt extruded amorphous solid dispersions.

T. De Beer, J. Remon, C. Vervaet, 2017, International journal of pharmaceutics.

Comparison of metoprolol tartrate multiple-unit lipid matrix systems produced by different technologies.

T. De Beer, C. Vervaet, P. Van Bockstal, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluation of spin freezing versus conventional freezing as part of a continuous pharmaceutical freeze-drying concept for unit doses.

T. De Beer, J. Remon, C. Vervaet, 2015, International journal of pharmaceutics.

The relevance of shear, sedimentation and diffusion during spin freezing, as potential first step of a continuous freeze-drying process for unit doses.

V. Vanhoorne, T. De Beer, C. Vervaet, 2018, International journal of pharmaceutics.

Global Sensitivity Analysis as Good Modelling Practices tool for the identification of the most influential process parameters of the primary drying step during freeze‐drying

T. De Beer, K. Gernaey, I. Nopens, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Quantitative risk assessment via uncertainty analysis in combination with error propagation for the determination of the dynamic Design Space of the primary drying step during freeze‐drying

Krist V. Gernaey, Ingmar Nopens, Séverine Thérèse F.C. Mortier, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

A primary drying model-based comparison of conventional batch freeze-drying to continuous spin-freeze-drying for unit doses.

T. De Beer, C. Vervaet, B. Vanbillemont, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Analysis of a pharmaceutical batch freeze dryer: resource consumption, hotspots, and factors for potential improvement

T. De Beer, J. Dewulf, P. Van Bockstal, 2019 .

Noncontact Infrared-Mediated Heat Transfer During Continuous Freeze-Drying of Unit Doses.

T. De Beer, C. Vervaet, L. De Meyer, 2017, Journal of pharmaceutical sciences.

Mechanistic modelling of infrared mediated energy transfer during the primary drying step of a continuous freeze‐drying process

T. De Beer, C. Vervaet, I. Nopens, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The generation and use of recombinant extracellular vesicles as biological reference material

I. Miinalainen, T. De Beer, J. Vandesompele, 2019, Nature Communications.

Hydrophilic thermoplastic polyurethanes for the manufacturing of highly dosed oral sustained release matrices via hot melt extrusion and injection molding.

T. De Beer, J. Remon, C. Vervaet, 2016, International journal of pharmaceutics.

Thermal Imaging as a Noncontact Inline Process Analytical Tool for Product Temperature Monitoring during Continuous Freeze-Drying of Unit Doses.

Chris Vervaet, Thomas De Beer, T. De Beer, 2018, Analytical chemistry.

Polymorphism of Indomethacin in Semicrystalline Dispersions: Formation, Transformation, and Segregation.

T. De Beer, P. Van Bockstal, J. van Humbeeck, 2018, Molecular pharmaceutics.

Development and Application of a Mechanistic Cooling and Freezing Model of the Spin Freezing Step within the Framework of Continuous Freeze-Drying

T. De Beer, C. Vervaet, B. Vanbillemont, 2021, Pharmaceutics.

Developing a framework to model the primary drying step of a continuous freeze‐drying process based on infrared radiation

T. De Beer, K. Gernaey, I. Nopens, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Impact of vacuum-induced surface freezing on inter- and intra-vial heterogeneity.

Roberto Pisano, Thomas De Beer, Irene Oddone, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Vacuum Induced Surface Freezing as an effective method for improved inter‐ and intra‐vial product homogeneity

T. De Beer, P. Van Bockstal, A. Barresi, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

A comparative study between melt granulation/compression and hot melt extrusion/injection molding for the manufacturing of oral sustained release thermoplastic polyurethane matrices.

T. De Beer, J. Remon, C. Vervaet, 2016, International journal of pharmaceutics.

Continuous manufacturing of delta mannitol by cospray drying with PVP.

V. Vanhoorne, E. Peeters, T. De Beer, 2016, International journal of pharmaceutics.

Formulation Optimization of Freeze-Dried Long-Circulating Liposomes and In-Line Monitoring of the Freeze-Drying Process Using an NIR Spectroscopy Tool.

P. Van Bockstal, S. Porav, I. Tomuță, 2018, Journal of pharmaceutical sciences.

Uncertainty analysis as essential step in the establishment of the dynamic Design Space of primary drying during freeze-drying.

Ingmar Nopens, Krist V Gernaey, Thomas De Beer, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Spin Freezing and Its Impact on Pore Size, Tortuosity and Solid State

T. De Beer, C. Vervaet, P. Van Bockstal, 2021, Pharmaceutics.