M. Gehring

发表

Design of enzyme inhibitors using iterative protein crystallographic analysis.

S. Freer, C. Janson, K. Appelt, 1991, Journal of medicinal chemistry.

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone.

L. Funk, P. Kung, J. Meng, 2008, Bioorganic & medicinal chemistry letters.

Abstract 2612: Effective targeting triple negative breast cancer cells by a novel oral heat shock protein 90 inhibitor PF-4942847

P. Kung, S. Yamazaki, M. Gehring, 2011 .

Purification of human matrilysin produced in Escherichia coli and characterization using a new optimized fluorogenic peptide substrate.

H. V. Van Wart, M. Gehring, M. Browner, 1995, Archives of biochemistry and biophysics.

Assay development and data analysis of receptor-ligand binding based on scintillation proximity assay.

M. Gehring, Jonathan V. Almaden, Shaoxian Sun, 2005, Metabolic engineering.

Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.

M. Gehring, S. Shi, Z. Tao, 2010, Biochemistry.

Involvement of tissue inhibitors of metalloproteinases (TIMPS) during matrix metalloproteinase activation.

K. Suzuki, K. Brew, M. Gehring, 1996, Advances in experimental medicine and biology.

Expression of Human Pro-Matrix Metalloproteinase 3 that Lacks the N-terminal 34 Residues in Escherichia coli: Autoactivation and Interaction with Tissue Inhibitor of Metalloproteinase 1 (TIMP-1)

K. Brew, M. Gehring, Ko Suzuki, 1998, Biological chemistry.

Modified nuclear processing of alpha 1-acid glycoprotein RNA during inflammation.

M. Gehring, G. Fey, B. Shiels, 1987, The Journal of biological chemistry.

Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.

K. Gajiwala, M. Hickey, P. Kung, 2010, Journal of medicinal chemistry.

Sequence and acute phase regulation of rat alpha 1-inhibitor III messenger RNA.

M. Gehring, G. Fey, B. Shiels, 1988, The Journal of biological chemistry.

Sequence of rat liver alpha 2-macroglobulin and acute phase control of its messenger RNA.

D. Noonan, M. Gehring, G. Fey, 1987, The Journal of biological chemistry.

Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis.

B. Mroczkowski, M. McTigue, K. Appelt, 1999, Structure.

Heterologous expression and purification of active human phosphoribosylglycinamide formyltransferase as a single domain

C. Janson, M. Gehring, Z. Hostomska, 1992, Journal of protein chemistry.

Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.

M. Gehring, G. Fey, E. Podack, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, Sergei L Timofeevski, 2020, ACS medicinal chemistry letters.

RETRACTED: A novel class of specific Hsp90 small molecule inhibitors demonstrate in vitro and in vivo anti-tumor activity in human melanoma cells.

P. Kung, S. Yamazaki, M. Gehring, 2011, Cancer letters.

Study of the PDK1/AKT signaling pathway using selective PDK1 inhibitors, HCS, and enhanced biochemical assays.

S. Gridley, G. Alton, M. Gehring, 2011, Analytical biochemistry.

Role of His-224 in the anomalous pH dependence of human stromelysin-1.

H. V. Van Wart, M. Gehring, C. Kan, 1999, Biochemistry.

Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. Identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyri

K. Gajiwala, M. Hickey, P. Kung, 2011, Journal of medicinal chemistry.

Characterization of the Phe-81 and Val-82 Human Fibroblast Collagenase Catalytic Domain Purified from Escherichia coli(*)

M. Gehring, B. Condon, S. Margosiak, 1995, The Journal of Biological Chemistry.

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

W. K. Sonnenburg, P. Kung, M. Gehring, 2020, ACS medicinal chemistry letters.