D. Buhler

发表

J. F. Stevens, C. Miranda, D. Buhler, 1998 .

Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression

Huiqing Zhan, Zhiyuan Gong, Yan Tong, 2006, Nature Biotechnology.

Heavy metals in estuarine shellfish from Oregon

R. Caldwell, D. Buhler, Donald R. Buhler, 1983, Archives of environmental contamination and toxicology.

Phenylthiourea as a weak activator of aryl hydrocarbon receptor inhibiting 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 transcription in zebrafish embryo.

D. Buhler, H. Wen, Chin-Hwa Hu, 2004, Biochemical pharmacology.

Influence of the Ah locus on the humoral immunotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: evidence for Ah-receptor-dependent and Ah-receptor-independent mechanisms of immunosuppression.

N. Kerkvliet, D. Buhler, M. Henderson, 1990, Toxicology and applied pharmacology.

Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva.

D. Buhler, Chin-Hwa Hu, Wen-Der Wang, 2005, Toxicology and applied pharmacology.

Nutrition of Salmonoid Fishes IX. Carbohydrate Requirements of Chinook Salmon

D. Buhler, J. Halver, 1961 .

The formation of 6,7-dihydro-7-hydroxy-1-hydroxy-methyl-5H-pyrrolizine, a metabolite of pyrrolizidine alkaloids.

D. Buhler, B. Kedzierski, 1986, Chemico-biological interactions.

Crosslinking of DNA by dehydroretronecine, a metabolite of pyrrolizidine alkaloids.

D. Buhler, G. D. Pearson, R. Reed, 1988, Carcinogenesis.

The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.

D. Buhler, W. Chung, Donald R. Buhler, 1994, Toxicology and applied pharmacology.

Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols.

S. Strom, P. Stapleton, D. Eaton, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from beta-naphthoflavone-fed rainbow trout.

D. Williams, D. Buhler, Donald R. Buhler, 1984, Biochemical pharmacology.

Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species.

J. F. Stevens, C. Miranda, D. Buhler, 2002, Journal of agricultural and food chemistry.

Influence of TCDD on zebrafish CYP1B1 transcription during development.

W. Tzou, D. Buhler, Hsin-Yu Chung, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Effect of xenoestrogen exposure on the expression of cytochrome P450 isoforms in rainbow trout liver

C. Miranda, D. Buhler, M. Henderson, 2002, Environmental toxicology and chemistry.

Plant polyphenols and multidrug resistance: Effects of dietary flavonoids on drug transporters in Caco-2 and MDCKII-MDR1 cell transport models

C. Miranda, D. Buhler, R. Rodriguez-Proteau, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in C57Bl/6 mice congenic at the Ah locus.

N. Kerkvliet, D. Buhler, M. Henderson, 1990, Fundamental and applied toxicology : official journal of the Society of Toxicology.

DECLINING RING-NECKED PHEASANTS IN THE KLAMATH BASIN, CALIFORNIA: II. SURVIVAL, PRODUCTIVITY, AND COVER

D. Buhler, C. Henny, R. Grove, 2001 .

CYP1A Induction by β-Naphthoflavone, Aroclor 1254, and 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Its Influence on Aflatoxin B1Metabolism and DNA Adduction in Zebrafish (Danio rerio)

D. Buhler, J. Hendricks, G. Bailey, 1997 .

Immunohistochemical localization of the cytochrome P450 isozymes LMC2 and LM4B (P4501A1) in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated zebrafish (Brachydanio rerio).

D. Buhler, A. Buchmann, K. Bock, 1993, Toxicology and applied pharmacology.

Effects of halogenated antibacterials on the erythrocyte membrane.

D. Buhler, T. Miller, P. L. Gaughan, 1978, Chemico-biological interactions.

Cloning, tissue distribution, and functional studies of a new cytochrome P450 3A subfamily member, CYP3A45, from rainbow trout (Oncorhynchus mykiss) intestinal ceca.

D. Buhler, Su Jun Lee, 2003, Archives of biochemistry and biophysics.

Cytochrome P-450 and Phase II activities in the gumboot chiton Cryptochiton stelleri

D. Buhler, D. Schlenk, 1988 .

Interaction of carbon tetrachloride with beta-naphthoflavone-mediated cytochrome P450 induction in winter flounder (Pseudopleuronectes americanus).

D. Williams, D. Buhler, K. Kleinow, 1990, Toxicology and applied pharmacology.

Regiospecific hydroxylation of lauric acid at the (omega-1) position by hepatic and kidney microsomal cytochromes P-450 from rainbow trout.

D. Williams, D. Buhler, B. Masters, 1984, Archives of biochemistry and biophysics.

Multiple effects of 3,4,5,3',4',5'-hexachlorobiphenyl administration on hepatic cytochrome P450 isozymes and associated mixed-function oxidase activities in rainbow trout.

C. Miranda, D. Buhler, Jun-Lan Wang, 1990, Biochemical pharmacology.

Cloning and characterization of a new cytochrome P450 from rainbow trout

D. Buhler, J. L. Wang, Y. H. Yang, 1996 .

Purification of cytochromes P-448 from β-naphthoflavone-treated rainbow trout

David E. Williams, D. Buhler, 1982 .

Cloning and sequencing of the major rainbow trout constitutive cytochrome P450 (CYP2K1): identification of a new cytochrome P450 gene subfamily and its expression in mature rainbow trout liver and trunk kidney.

T. Dreher, C. Miranda, D. Buhler, 1994, Archives of biochemistry and biophysics.

Differential effects of 3,4,5,3',4',5'-hexachlorobiphenyl (HCB) on interrenal steroidogenesis in male and female rainbow trout Oncorhynchus mykiss.

C. Miranda, D. Buhler, J. Hendricks, 1992, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Beta-naphthoflavone induced CYP1A1 and 1A3 proteins in the liver of rainbow trout (Oncorhynchus mykiss).

C. Miranda, D. Buhler, R. Gooneratne, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Effects of 3,3′,4,4′,5,5′‐hexachlorobiphenyl on cytochrome P4501A and estrogen‐induced vitellogenesis in rainbow trout (Oncorhynchus mykiss)

D. Buhler, L. Curtis, R. Donohoe, 1999 .

Cytochrome P450 Expression in Rainbow Trout: An Overview

D. Buhler, 1995 .

Comparative properties of purified cytochrome P-448 from beta-naphthoflavone treated rats and rainbow trout.

D. Williams, D. Buhler, Donald R. Buhler, 1983, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Immunochemical analysis of liver microsomal cytochromes P450 of the American alligator, Alligator mississippiensis.

D. Buhler, J. Stegeman, S. Bandiera, 1999, Toxicology and applied pharmacology.

The oxidation of drugs by fishes.

D. Buhler, M. Rasmusson, 1968, Comparative biochemistry and physiology.

Immunohistochemical localization and differential expression of cytochrome P450 3A27 in the gastrointestinal tract of rainbow trout.

D. Buhler, I. Cok, A. Şen, 2001, Toxicology and applied pharmacology.

Purified form of cytochrome P-450 from rainbow trout with high activity toward conversion of aflatoxin B1 to aflatoxin B1-2,3-epoxide.

D. Williams, D. Buhler, D. Williams, 1983, Cancer research.

Induction of lauric acid hydroxylase activity in catfish and bluegill by peroxisome proliferating agents.

D. Buhler, M. Haasch, M. Henderson, 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Induction of CYP2M1 and CYP2K1 lauric acid hydroxylase activities by peroxisome proliferating agents in certain fish species: Possible implications

D. Buhler, M. Haasch, M. Henderson, 1998 .

Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.

D. Buhler, A. Craig, J. Duringer, 2004, American journal of veterinary research.

Differential metabolism of the pyrrolizidine alkaloid, senecionine, in fischer 344 and sprague-dawley Rats

D. Buhler, W. Chung, 2004, Archives of pharmacal research.

Functional properties of a rainbow trout CYP3A27 expressed by recombinant baculovirus in insect cells.

D. Buhler, Su-Jun Lee, 2002, Drug metabolism and disposition: the biological fate of chemicals.

In vitro biotransformation of xanthohumol, a flavonoid from hops (Humulus lupulus), by rat liver microsomes.

J. F. Stevens, D. Buhler, M. Deinzer, 2001, Drug metabolism and disposition: the biological fate of chemicals.

In vitro glucuronidation of xanthohumol, a flavonoid in hop and beer, by rat and human liver microsomes

J. F. Stevens, D. Buhler, M. Yilmazer, 2001, FEBS letters.

Species differences in the hepatic microsomal enzyme metabolism of the pyrrolizidine alkaloids.

C. Miranda, D. Buhler, P. Cheeke, 1998, Toxicology letters.

A cytochrome P4502B form is the major bioactivation enzyme for the pyrrolizidine alkaloid senecionine in guinea pig.

C. Miranda, D. Buhler, W. Chung, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

Microsomal formation of a pyrrolic alcohol glutathione conjugate of the pyrrolizidine alkaloid senecionine.

C. Miranda, D. Buhler, M. Henderson, 1992, Xenobiotica; the fate of foreign compounds in biological systems.

Comparative effects of the polychlorinated biphenyl mixture, Aroclor 1242, on porphyrin and xenobiotic metabolism in kidney of Japanese quail and rat.

C. Miranda, D. Buhler, M. Henderson, 1992, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Flavin-containing monooxygenase: a major detoxifying enzyme for the pyrrolizidine alkaloid senecionine in guinea pig tissues.

R. E. Reed, D. Williams, C. Miranda, 1991, Biochemical and biophysical research communications.

Microsomal metabolism of pyrrolizidine alkaloids: N-oxidation of seneciphylline and senecionine.

H. Ramsdell, D. Buhler, 1987, Toxicology letters.

Differential induction of hepatic drug metabolizing enzymes in Japanese quail by 1,2,4-trichlorobenzene.

C. Miranda, D. Buhler, H. Carpenter, 1983, Toxicology.

Studies on the porphyrinogenic action of 1,2,4-trichlorobenzene in birds.

C. Miranda, D. Buhler, H. Carpenter, 1983, Toxicology.

Protective role of dietary butylated hydroxyanisole against chemical-induced acute liver damage in mice.

J. A. Schmitz, C. Miranda, D. Buhler, 1983, Toxicology and applied pharmacology.

Protective action of zinc against pyrrolizidine alkaloid-induced hepatotoxicity in rats.

J. A. Schmitz, C. Miranda, D. Buhler, 1982, Journal of toxicology and environmental health.

Metabolism and tumorigenicity of 7-, 8-, 9-, and 10-fluorobenzo(a)pyrenes.

T. Slaga, D. Jerina, D. Buhler, 1982, Cancer research.

Protective effects of butylated hydroxyanisole against the acute toxicity of monocrotaline in mice.

C. Miranda, D. Buhler, P. Cheeke, 1981, Toxicology and applied pharmacology.

Effect of ethoxyquin on the toxicity of the pyrrolizidine alkaloid monocrotaline and on hepatic drug metabolism in mice.

C. Miranda, D. Buhler, H. Carpenter, 1981, Chemico-biological interactions.

Effect of pyrrolizidine alkaloids from tansy ragwort (senecio jacobaea) on hepatic drug-metabolizing enzymes in male rats.

C. Miranda, D. Buhler, P. Cheeke, 1980, Biochemical pharmacology.

Flavin-containing monooxygenase activity in liver microsomes from the rainbow trout (Oncorhynchus mykiss)

D. Buhler, D. Schlenk, 1991 .

Role of flavin-containing monooxygenase in the in vitro biotransformation of aldicarb in rainbow trout (Oncorhynchus mykiss).

D. Buhler, D. Schlenk, 1991, Xenobiotica; the fate of foreign compounds in biological systems.

Xenobiotic biotransformation in the Pacific oyster (Crassostrea gigas).

D. Buhler, D. Schlenk, 1989, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Effects of 2‐methylisoborneol (MIB), and ethanol on the expression and activity of cytochrome P450s from the channel catfish

C. Miranda, D. Buhler, M. Ronis, 1995 .

Alterations in hepatic microsomal protein levels in rainbow trout fed cyclopropenoid fatty acids analyzed by two-dimensional gel electrophoresis.

H. W. Schaup, D. Williams, D. Buhler, 1988, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Cytochrome P-450-mediated covalent binding of hexachlorophene to rat tissue proteins.

D. Buhler, M. Henderson, A. Miller, 1978, Molecular pharmacology.

Inhibition of in vitro aflatoxin B1-DNA binding in rainbow trout by CYP1A inhibitors: α-naphthoflavone, β-naphthoflavone and trout CYP1A1 peptide antibody

David E. Williams, C. Miranda, D. Buhler, 1995 .

Induction of zebrafish (Brachydanio rerio) P450 in vivo and in cell culture.

C. Miranda, D. Buhler, P. Collodi, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

cDNA-directed expression of a functional zebrafish CYP1A in yeast.

C. Miranda, D. Buhler, Nathan I. Lopez, 2004, Aquatic toxicology.

Regulation of cytochrome P450 expression in a novel liver cell line from zebrafish (Brachydanio rerio).

C. Miranda, D. Buhler, P. Collodi, 1993, Archives of biochemistry and biophysics.

Comparative in vitro metabolism of benzo[a]pyrene by recombinant zebrafish CYP1A and liver microsomes from beta-naphthoflavone-treated rainbow trout.

C. Miranda, D. Buhler, W. Baird, 2006, Aquatic toxicology.

Cloning, sequencing, and characterization of CYP1A1 cDNA from leaping mullet (Liza Saliens) liver and implications for the potential functions of its conserved amino acids

D. Buhler, E. Urbach, A. Şen, 2001, Journal of biochemical and molecular toxicology.

Neoplasia and neoplasm-associated lesions in laboratory colonies of zebrafish emphasizing key influences of diet and aquaculture system design.

D. Buhler, J. Spitsbergen, T. S. Peterson, 2012, ILAR journal.

Cytochrome P-450 isozymes in salmonids determined with antibodies to purified forms of P-450 from rainbow trout

R. C. Bender, David E. Williams, D. Buhler, 1984 .

Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase.

C. Miranda, D. Buhler, M. Henderson, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Dieldrin pretreatment alters [14C]dieldrin and [3H]7,12-dimethylbenz[a]anthracene uptake in rainbow trout liver slices.

C. Miranda, D. Buhler, L. K. Siddens, 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Metabolism of 2-methylnaphthalene by rat and rainbow trout hepatic microsomes and purified cytochromes P-450.

D. Williams, D. Buhler, J. Lech, 1985, Drug metabolism and disposition: the biological fate of chemicals.

Hexachlorobenzene-induced porphyria in Japanese quail. Effect of pretreatment with phenobarbital or beta-naphthoflavone.

R. C. Bender, D. Williams, D. Buhler, 1984, Biochemical pharmacology.

Expression of CYP2M1, CYP2K1, and CYP3A27 in brain, blood, small intestine, and other tissues of rainbow trout.

C. Miranda, D. Buhler, I. Cok, 1998, Biochemical and biophysical research communications.

Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.

D. Williams, D. Buhler, F. Guengerich, 1989, Drug metabolism and disposition: the biological fate of chemicals.

Hydroxylation; the activation of oxygen by peroxidase.

D. Buhler, H. S. Mason, I. Onopryenko, 1957, Biochimica et biophysica acta.

Prenylflavonoids from hops inhibit the metabolic activation of the carcinogenic heterocyclic amine 2-amino-3-methylimidazo[4, 5-f]quinoline, mediated by cDNA-expressed human CYP1A2.

J. F. Stevens, C. Miranda, D. Buhler, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Flavin-containing monooxygenase activity in the gumboot chitonCryptochiton stelleri

D. Buhler, D. Schlenk, 1990 .

Effect of a 6-fluoro substituent on the metabolism and biological activity of benzo(a)pyrene.

T. Slaga, D. Jerina, D. Buhler, 1983, Cancer research.

The regiospecific hydroxylation of lauric acid by rainbow trout (Oncorhynchus mykiss) cytochrome P450s.

C. Miranda, D. Buhler, M. Deinzer, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes.

D. Williams, C. Miranda, D. Buhler, 1990, Biochemical and Biophysical Research Communications - BBRC.

Declining Ring-necked Pheasants in the Klamath Basin, California: I. Insecticide Exposure

D. Buhler, C. Henny, R. Grove, 1998 .

Hydroxylation catalyzed by peroxidase

D. Buhler, H. S. Mason, 1961 .

A comparison of the effects of hexachlorobenzene, beta-naphthoflavone, and phenobarbital on cytochrome P-450 and mixed-function oxidases in Japanese quail.

D. Williams, D. Buhler, H. Carpenter, 1985, Journal of toxicology and environmental health.

In vitro metabolism of 7,12-dimethylbenz[a]anthracene by rainbow trout liver microsomes and trout P450 isoforms.

D. Williams, C. Miranda, D. Buhler, 1997, Toxicology and applied pharmacology.

Multiple Hemoglobins in Fishes

D. Buhler, W. E. Shanks, 1959, Science.

Bilateral Uric Acid Nephrolithiasis and Ureteral Hypertrophy in a Free-ranging River Otter (Lontra canadensis)

D. Buhler, R. Bildfell, C. Henny, 2003, Journal of wildlife diseases.

Biliary Metabolites and Enterohepatic Circulation of Hexachlorophene in the Rat

A. J. Gandolfi, D. Buhler, A. Gandolfi, 1974 .

A simple scintillation counting technique for assaying C1402 in a Warburg flask.

D. Buhler, 1962, Analytical biochemistry.

Cloning, sequencing and expression of the major rainbow trout constitutive cytochrome P450 (CYP2K1). Identification of a new cytochrome P450 gene subfamily

T. Dreher, C. Miranda, D. Buhler, 1995 .

Effect of hexachlorophene on monovalent cation transport in human erythrocytes. A mechanism for hexachlorophene-induced hemolysis.

D. Buhler, T. Miller, 1974, Biochimica et biophysica acta.

Role of metabolism in monocrotaline-induced immunotoxicity in C57BL/6 mice.

N. Kerkvliet, D. Buhler, J. Deyo, 1994, Toxicology.

Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases.

J. A. McCrary, D. Buhler, R. Novak, 1992, Carcinogenesis.

Nuclear Magnetic Resonance Spectroscopy in Pesticide Chemistry

D. Buhler, R. Haque, 1972 .

Effect of sheep rumen fermentation and methane inhibition on the toxicity of Senecio jacobaea.

H. Ramsdell, D. Buhler, R. Swick, 1983, Journal of animal science.

The Relative Contributions of Methylmercury from Food or Water to Rainbow Trout (Salmo gairdneri) in a Controlled Laboratory Environment

D. Buhler, G. R. Phillips, 1978 .

Identification and Estimation of Catabolic Pathways of Glucose in Fruits.

C. Wang, D. Buhler, R. D. Barbour, 1958, Plant physiology.

Covalent binding of carbaryl (1-naphthyl-N-methyl-carbamate) to rat liver microsomes in vitro.

D. Buhler, M. Henderson, A. Miller, 1979, Chemico-biological interactions.

Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF‐κB and Akt as targets

D. Noonan, A. Albini, D. Buhler, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.

J. F. Stevens, C. Miranda, D. Buhler, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Anodic fluorination of benz[a]anthracene

D. Jerina, D. Buhler, R. F. O'Malley, 1981 .

Culture of cells from zebrafish (Brachydanio rerio) embryo and adult tissues

C. Miranda, D. Buhler, P. Collodi, 2004, Cell Biology and Toxicology.

Effect of feeding milk from goats fed tansy ragwort (Senecio jacobaea) to rats and calves.

D. Buhler, P. Cheeke, D. Goeger, 1982, American Journal of Veterinary Research.

Toxicity of tansy ragwort (Senecio jacobaea) to goats.

J. A. Schmitz, D. Buhler, P. Cheeke, 1982, American journal of veterinary research.

Effect of consumption of milk from goats fed Senecio jacobaea on hepatic drug metabolizing enzyme activities in rats.

C. Miranda, D. Buhler, P. Cheeke, 1981, Toxicology letters.

Determination of Senecio alkaloids by thermospray liquid chromatography/mass spectrometry.

K. Tomer, D. Buhler, R. Reed, 1990, Biomedical & environmental mass spectrometry.

Method for determination of pyrrolizidine alkaloids and their metabolites by high-performance liquid chromatography.

D. Buhler, B. Kedzierski, Bogdan Kedzierski, 1986, Analytical biochemistry.

Mutagenic responses of tansy ragwort (Senecio jacobaea) plant, pyrrolizidine alkaloids and metabolites in goat milk with the Salmonella/mammalian-microsome mutagenicity test.

D. Buhler, M. Deinzer, P. Cheeke, 1984, Journal of animal science.

An evaluation of acetone extracts from six plants in the Ames mutagenicity test.

D. Buhler, P. Cheeke, R. D. White, 1983, Toxicology letters.

Absorption and excretion of pyrrolizidine (Senecio) alkaloids and their effects on mineral metabolism in rabbits.

D. Buhler, R. Swick, P. Cheeke, 1982, Journal of animal science.

Effect of dietary Senecio jacobaea and injected Senecio alkaloids and monocrotaline on guinea pigs.

D. Buhler, R. Swick, P. Cheeke, 1982, Journal of animal science.

Gas chromatographic determination of pyrrolizidine alkaloids in goat's milk.

D. Buhler, M. Deinzer, B. Arbogast, 1982 .

The synthesis of 3H-putrescine and subsequent biosynthesis of 3H-jacobine, a pyrrolizidine alkaloid from Senecio Jacobaea

D. Buhler, R. Reed, 1988 .

Biological reactive intermediates of pyrrolizidine alkaloids.

D. Buhler, B. Kedzierski, 1986, Advances in experimental medicine and biology.

Comparison of the toxicities of Senecio jacobaea, Senecio vulgaris and Senecio glabellus in rats.

H. Ramsdell, D. Buhler, S. S. Nicholson, 1983, Toxicology letters.

High-performance liquid chromatographic analysis of pyrrolizidine (Senecio) alkaloids using a reversed-phase styrene-divinylbenzence resin column

H. Ramsdell, D. Buhler, 1981 .

Toxicity of Senecio jacobaea (tansy ragwort) in rats.

J. A. Schmitz, C. Miranda, D. Buhler, 1980, Toxicology and applied pharmacology.

Liver and kidney pathology in rainbow trout (Salmo gairdneri) exposed to dietary pyrrolizidine (Senecio) alkaloids.

D. Buhler, J. Hendricks, R. Sinnhuber, 1981, Experimental and molecular pathology.

Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro.

J. F. Stevens, C. Miranda, D. Buhler, 2000, Journal of agricultural and food chemistry.

Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes.

J. F. Stevens, C. Miranda, D. Buhler, 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Metallothionein and the subcellular localization of mercury and cadmium in the California sea lion.

B. Mate, D. Buhler, R. Rimerman, 1977, Comparative biochemistry and physiology. C: Comparative pharmacology.

CYP2K6 from zebrafish (Danio rerio): cloning, mapping, developmental/tissue expression, and aflatoxin B1 activation by baculovirus expressed enzyme.

M. Westerfield, J. F. Stevens, C. Miranda, 2005, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.

C. Miranda, D. Buhler, P. Cheeke, 1998, Toxicology and applied pharmacology.

Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver.

C. Miranda, D. Buhler, F. Guengerich, 1991, Carcinogenesis.

The role of flavin-containing monooxygenase in the N-oxidation of the pyrrolizidine alkaloid senecionine.

B Kedzierski, D. Williams, D. Buhler, 1989, Drug metabolism and disposition: the biological fate of chemicals.

The use of mussels to determine the extent of trace metal contamination along Moroccan Atlantic coast

D. Buhler, A. E. Hraiki, M. Alaout, 1994 .

' THE CONVERSION OF C 1402 AND CH 3C 140-COOH TO CITRIC AND MALIC ACIDS IN THE TOMATO FRUITS 1 ' 2

D. Buhler, B. E. Christensen, 2022 .

Status and opportunities for genomics research with rainbow trout.

Caird Rexroad, Patrick J Walsh, D. Buhler, 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

CHARACTERIZATION OF THE GLUCURONIDE CONJUGATE OF CHLORPHENESIN CARBAMATE FROM THE RAT AND FROM MAN.

D. Buhler, 1965, Biochemical pharmacology.

THE METABOLISM OF CHLORPHENESIN CARBAMATE.

D. Buhler, 1964, The Journal of pharmacology and experimental therapeutics.

Metabolism of 3-(p-Chlorophenoxy)-2-MethoxypropyI Garbamate in the Rat

D. Buhler, H. Harpootlian, 1967, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

The Conversion of C14O2 and CH3-C14O-COOH to Citric and Malic Acids in the Tomato Fruits

D. Buhler, E. Hansen, CHIH H. Wang, 1956 .

Epimerization and Fragmentation of Glucose by Quaternary Ammonium Base Type Anion Exchange Resins 1

D. Buhler, Richard C. Thomas, CHIH H. Wang, 1955 .

Chronic oral DDT toxicity in juvenile Coho and Chinook salmon.

D. Buhler, M. Rasmusson, W. E. Shanks, 1969, Toxicology and applied pharmacology.

Hemolytic properties of hexachlorophene and related chlorinated bisphenols.

D. Buhler, G. Flores, 1974, Biochemical Pharmacology.

Effects of chlorinated bisphenols on torula yeast glucose-6-phosphate dehydrogenase.

D. Buhler, J. L. Wang, 1981, Journal of toxicology and environmental health.

Effect of hexachlorophene, tribromsalan, trichlorcarban and cloflucarban on hexobarbital sleeping time and hepatic drug-metabolizing enzyme activity in vitro in the rat.

D. Buhler, L. Condie, 1979, Biochemical pharmacology.

Percutaneous absorption of hexachlorophene in the rat.

D. Buhler, H. Nakaue, 1976, Toxicology and applied pharmacology.

Studies on the toxicity of hexachlorophene in the rat.

F. Dost, D. Buhler, H. Nakaue, 1973, Toxicology and applied pharmacology.

Biochemical lesion in rat liver mitochondria induced by hexachlorophene.

R. Caldwell, D. Buhler, H. Nakaue, 1972, Biochemical pharmacology.

Bisphenols--uncouplers of phosphorylating respiration.

R. Caldwell, D. Buhler, H. Nakaue, 1972, Biochemical pharmacology.

A proton magnetic resonance study of the interaction of hexachlorophene with amides and polypeptides.

D. Buhler, R. Haque, 1972, Journal of the American Chemical Society.

IDENTIFICATION AND ESTIMATION OF CATABOLIC PATHWAYS OF GLUCOSE IN FRUITS 1 ' 2

C. H. Wang, D. Buhler, R. D. Barbour, 2004 .

DARK FIXATION OF C 02 BY SUCCULENT LEAVES : CONSERVATION OF THE DARK FIXED C 02 UNDER DIURNAL CONDITIONS 1 " 2

C. Wang, D. Buhler, R. D. Barbour, 2004 .

Reduction of p-nitrobenzoic acid by fishes.

D. Buhler, M. Rasmusson, 1968, Archives of biochemistry and biophysics.

Purification and comparative properties of NADPH-cytochrome P-450 reductase from rat and rainbow trout: differences in temperature optima between reconstituted and microsomal trout enzymes.

D. Williams, D. Buhler, F. Guengerich, 1983, Archives of biochemistry and biophysics.

Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells.

J. F. Stevens, C. Miranda, D. Buhler, 2000, Cancer letters.

Sex differences in cytochrome P-450 isozyme composition and activity in kidney microsomes of mature rainbow trout.

D. Williams, D. Buhler, B. Masters, 1986, Biochemical pharmacology.

Hepatic uroporphyrin accumulation and uroporphyrinogen decarboxylase activity in cultured chick-embryo hepatocytes and in Japanese quail (Coturnix coturnix japonica) and mice treated with polyhalogenated aromatic compounds.

D. Buhler, G. Elder, P. Sinclair, 1988, The Biochemical journal.

Preparation of tritium-labeled compounds. II. Chlorphenesin carbamate by exposure to tritium gas and determination of intramolecular distribution of tritium.

D. Buhler, R. Thomas, G. Ikeda, 1967, Journal of pharmaceutical sciences.

Synthesis of Tertiary Carbon14—Labeled DDT1,2

D. Buhler, B. E. Christensen, C. H. Wang, 1953 .

Incorporation of Ethylene into Fruits

C. H. Wang, C. Wang, D. Buhler, 1957, Nature.

4.9 – Pyrrole

D. Buhler, R. Howe, 1990 .

Mouse Skin Tumor-Initiating Activity of 5-, 7-, and 12-Methyl-and Fluorine-Substituted 8 enz [ a ]

T. Slaga, D. Jerina, D. Buhler, 2012 .

Cytochrome P450 isozyme distribution in normal and tumor-bearing hepatic tissue from rainbow trout (Salmo gairdneri).

D. Buhler, R. Lorenzana, O. Hedstrom, 1989, Experimental and molecular pathology.

Alterations in cytochrome P-450 levels in adult rats following neonatal exposure to xenobiotics.

D. Buhler, R. Zangar, D. Springer, 1993, Journal of toxicology and environmental health.

Metabolism of 3α-hydroxy-5β-pregnane-11,20-dione-73H, cyclic 20-trimethylene acetal in man

D. Buhler, 1966 .

In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

J. F. Stevens, C. Miranda, D. Buhler, 2000, Xenobiotica; the fate of foreign compounds in biological systems.

Evaluation of chemicals as inhibitors of trout cytochrome P450s.

C. Miranda, D. Buhler, M. Henderson, 1998, Toxicology and applied pharmacology.

Xenobiotics and xenoestrogens in fish: modulation of cytochrome P450 and carcinogenesis.

D. Williams, D. Buhler, J. Lech, 1998, Mutation research.

Effect of phenobarbital on toxicity of pyrrolizidine (Senecio) alkaloids in sheep.

C. Miranda, D. Buhler, R. Swick, 1983, Journal of animal science.

The effects of a luteinizing hormone-releasing hormone analogue on cytochrome P450 in rainbow trout

C. Miranda, D. Buhler, M. Henderson, 1995 .

Effect of Feeding and of DDT on the Activity of Hepatic Glucose 6-Phosphate Dehydrogenase in Two Salmonids

D. Buhler, P. Benville, 1969 .

Down regulation of hepatic flavin-containing monooxygenase activity by 17 beta-estradiol in rainbow trout (Oncorhynchus mykiss).

D. Buhler, D. Schlenk, A. El-Alfy, 1997, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Channel catfish liver monooxygenases. Immunological characterization of constitutive cytochromes P450 and the absence of active flavin-containing monooxygenases.

C. Miranda, D. Buhler, M. Ronis, 1993, Biochemical pharmacology.

The effect of thermal acclimation on the activity of arylhydrocarbon hydroxylase in rainbow trout (Oncorhynchus mykiss).

D. Williams, D. Buhler, H. Carpenter, 1990, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Inhibition of dehydrogenase enzymes by hexachlorophene.

D. Buhler, J. L. Wang, 1978, Biochemical pharmacology.

Effect of ehxachlorophene on hepatic drug-metabolizing enzymes in the rat.

A. J. Gandolfi, D. Buhler, H. S. Nakue, 1974, Biochemical pharmacology.

Studies on fish hemoglobins. Chinook salmon and rainbow trout.

D. Buhler, D R BUHLER, 1963, The Journal of biological chemistry.

The effect of consumption of the pyrrolizidine alkaloid-containing plant Senecio jacobaea on iron and copper metabolism in the rat.

C. Miranda, D. Buhler, R. Swick, 1982, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.

Subcellular distribution of hepatic copper, zinc and iron and serum ceruloplasmin in rats intoxicated by oral pyrrolizidine (Senecio) alkaloids.

D. Buhler, R. Swick, P. Cheeke, 1982, Journal of animal science.

Dietary copper enhances the hepatotoxicity of Senecio jacobaea in rats.

C. Miranda, D. Buhler, M. Henderson, 1981, Toxicology and applied pharmacology.

Tissue Accumulation and Enzymatic Effects of Hexavalent Chromium in Rainbow Trout (Salmo gairdneri)

R. Caldwell, D. Buhler, R. M. Stokes, 1977 .

β-Naphthoflavone induced CYP1A1 and 1A3 proteins in the liver of rainbow trout (Oncorhynchus mykiss)

C. Miranda, D. Buhler, R. Gooneratne, 1997 .

Inhibition of in vitro aflatoxin B1-DNA binding in rainbow trout by CYP1A inhibitors: alpha-naphthoflavone, beta-naphthoflavone and trout CYP1A1 peptide antibody.

D. Williams, C. Miranda, D. Buhler, 1995, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Influences of Dieldrin on the Growth and Body Composition of Fingerling Rainbow Trout (Salmo gairdneri) Fed Oregon Moist Pellets or Tubificid Worms (Tubifex sp.)

D. Buhler, G. R. Phillips, 1979 .

Immunological characterization of flavin-containing monooxygenases from the liver of rainbow trout (Oncorhynchus mykiss): sexual- and age-dependent differences and the effect of trimethylamine on enzyme regulation.

D. Buhler, D. Schlenk, 1993, Biochimica et biophysica acta.

Occurrence of hexachlorophene and pentachlorophenol in sewage and water

D. Buhler, M. Rasmusson, H. Nakaue, 1973 .

The absorption, excretion, and metabolism of chlorphenesin carbamate in the dog.

D. Buhler, H. Harpootlian, R. L. Johnston, 1966, Biochemical pharmacology.

The N- and C-terminal amino acids of human hemoglobin H.

D. Buhler, D. Rigas, 1962, Biochimica et biophysica acta.

The effect of tetrachlorohydroquinone on hexachlorobenzene-induced porphyria in Japanese quail.

D. Buhler, H. Carpenter, M. J. Harvey, 1985, Journal of toxicology and environmental health.

Advocating Complete Sequencing of the Genome of the Rainbow Trout , Oncorhynchus mykiss

B. May, F. Allendorf, R. Guyomard, 2002 .

Genotoxicity of the pyrrolizidine alkaloid jacobine in rats.

D. Buhler, G. T. Bowden, I. Sipes, 1986, Toxicology letters.

Pyrrolizidine alkaloid-induced alterations in benzo[alpha]pyrene metabolism and binding of benzo[alpha]pyrene metabolites to deoxyribonucleic acid.

D. Williams, C. Miranda, D. Buhler, 1983, Biochemical pharmacology.

Configuration of necine pyrroles--toxic metabolites of pyrrolizidine alkaloids.

D. Buhler, B. Kedzierski, 1985, Toxicology letters.

Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes.

C. Miranda, D. Buhler, P. Cheeke, 1982, Toxicology letters.

Immunochemical cross-reactivity ofβ-naphthoflavone-inducible cytochrome P450 (P450IA) in liver microsomes from different fish species and rat

David E. Williams, D. Buhler, J. Stegeman, 1991, Fish Physiology and Biochemistry.

Cadmium absorption and tissue distribution in rats provided low concentrations of cadmium in food or drinking water.

D. Buhler, K. Smith, D. Wright, 1981, Journal of toxicology and environmental health.

Comparison of rainbow trout and mammalian cytochrome P450 enzymes: evidence for structural similarity between trout P450 LMC5 and human P450IIIA4.

C. Miranda, D. Buhler, F. Guengerich, 1991, Biochemical and biophysical research communications.

Neonatal exposure to xenobiotics alters adult hepatic protein kinase C alpha levels and testosterone metabolism: differential effects by diethylstilbestrol and phenobarbital.

D. Buhler, R. Zangar, D. Springer, 1995, Journal of toxicology and environmental health.

Effects of 17β-Estradiol and Testosterone on Hepatic mRNA/Protein Levels and Catalytic Activities of CYP2M1, CYP2K1, and CYP3A27 in Rainbow Trout (Oncorhynchus mykiss)

C. Miranda, D. Buhler, Su-Jun Lee, 2000 .

A predictive model for the accumulation of cadmium by container-grown plants

D. Buhler, Y. Wong, C. L. Browne, 1984 .

Effects of polychlorinated biphenyls on porphyrin synthesis and cytochrome P-450-dependent monooxygenases in small intestine and liver of Japanese quail.

C. Miranda, D. Buhler, M. Henderson, 1987, Journal of toxicology and environmental health.

ABSORPTION, METABOLISM AND EXCRETION OF 6-ALPHA-METHYL-PREDNISOLONE-3H,21-ACETATE FOLLOWING ORAL AND INTRAMUSCULAR ADMINISTRATIONS IN THE DOG.

C. Schlagel, D. Buhler, R. Thomas, 1965, Endocrinology.

1.1 – Allylamine

D. Buhler, Jun-Lan Wang, 1990 .

Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes

S. Safe, S. Strom, P. Stapleton, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Mouse skin tumor-initiating activity of 5-, 7-, and 12-methyl- and fluorine-substituted benz[a]anthracenes.

T. Slaga, D. Jerina, D. Buhler, 1982, Journal of the National Cancer Institute.

Hexachlorobenzene-induced porphyria in Japanese quail: an in vitro study of changes in cytochrome P-450 and monooxygenases.

D. Williams, D. Buhler, H. Carpenter, 1985, Journal of toxicology and environmental health.

Analysis of denatonium benzoate in Oregon consumer products by HPLC.

D. Buhler, C. Neumann, M. Henderson, 1998, Chemosphere.

Microsomal metabolism of pyrrolizidine alkaloids from Senecio jacobaea. Isolation and quantification of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine and N-oxides by high performance liquid chromatography.

H. Ramsdell, D. Buhler, B. Kedzierski, 1987, Drug metabolism and disposition: the biological fate of chemicals.

CYP2M1: cloning, sequencing, and expression of a new cytochrome P450 from rainbow trout liver with fatty acid (omega-6)-hydroxylation activity.

C. Miranda, D. Buhler, J. L. Wang, 1998, Archives of biochemistry and biophysics.

Influence of Body Weight on Chronic Oral DDT Toxicity in Coho Salmon

D. Buhler, W. E. Shanks, 1970 .

Cloning, sequencing, and tissue expression of CYP3A27, a new member of the CYP3A subfamily from embryonic and adult rainbow trout livers.

C. Miranda, D. Buhler, J. Lech, 1998, Archives of biochemistry and biophysics.

Immunological characterization of constitutive isozymes of cytochrome P-450 from rainbow trout. Evidence for homology with phenobarbital-induced rat P-450s.

C. Miranda, D. Buhler, M. Henderson, 1990, Biochimica et biophysica acta.

Rainbow trout cytochrome P450s: purification, molecular aspects, metabolic activity, induction and role in environmental monitoring.

D. Buhler, J. Wang-Buhler, J. Wang‐Buhler, 1998, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Influence of tansy ragwort (Senecio jacobaea), dietary copper, and feed restriction on the subcellular distribution of minerals in rat liver.

C. Miranda, D. Buhler, M. Henderson, 1984, Toxicology and applied pharmacology.

Alterations in lipid peroxidation, antioxidant enzymes, and carcinogen metabolism in liver microsomes of vitamin E-deficient trout and rat.

D. Williams, D. Buhler, H. Carpenter, 1992, Toxicology and applied pharmacology.

Inhibition of Peroxynitrite-Mediated LDL Oxidation by Prenylated Flavonoids: The α,β-Unsaturated Keto Functionality of 2‘-Hydroxychalcones as a Novel Antioxidant Pharmacophore

J. F. Stevens, C. Miranda, D. Buhler, 2003 .

The role of biotransformation in the toxicity of chemicals

David E. Williams, D. Buhler, 1988 .

Hepatic cytochrome P-450 isozymes and aryl hydrocarbon hydroxylase in English sole (Parophrys vetulus).

T. Collier, D. Buhler, U. Varanasi, 1986, Biochemical pharmacology.

Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish

C. Miranda, D. Buhler, J. Stegeman, 1996, Fish Physiology and Biochemistry.

Chemotherapy of hexamitiasis in fish.

D. Buhler, W. T. Yasutake, W. E. Shanks, 1961, The Journal of parasitology.

5.11 – Valeronitrile

D. Buhler, Jun-Lan Wang, 1990 .

Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout.

C. Miranda, D. Buhler, M. Henderson, 1989, Archives of biochemistry and biophysics.

CYP3C1, the first member of a new cytochrome P450 subfamily found in zebrafish (Danio rerio).

D. Buhler, G. Corley-Smith, Chin-Hwa Hu, 2006, Biochemical and biophysical research communications.

5.5 – Benzonitrile

D. Buhler, Jun-Lan Wang, 1990 .

CYP1B1 knockdown does not alter synergistic developmental toxicity of polycyclic aromatic hydrocarbons in zebrafish (Danio rerio).

D. Buhler, R. D. Di Giulio, A. Timme-Laragy, 2008, Marine environmental research.

Hexachlorobenzene-induced porphyria in Japanese quail: changes in microsomal enzymes.

D. Williams, D. Buhler, H. Carpenter, 1985, Journal of toxicology and environmental health.

5.6 – Benzyl Cyanide

D. Buhler, Jun-Lan Wang, 1990 .

Heavy Metal and Chlorinated Hydrocarbon Residues in California Sea Lions (Zalophus californianus californianus)

B. Mate, D. Buhler, R. Claeys, 1975 .

Dietary butylated hydroxyanisole reduces covalent binding of acetaminophen to mouse tissue proteins in vivo.

C. Miranda, D. Buhler, M. Henderson, 1985, Toxicology letters.

Distribution of inorganic elements of poultry house dust.

G. H. Arscott, D. Buhler, J. Koelliker, 1981, Poultry science.

Immunological and biochemical characterization of cytochromes P-450 in mullet (Mugil cephalus): comparison with rainbow trout P-450s.

C. Miranda, D. Buhler, M. Henderson, 1994, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Localization of cytochrome P-450 in the head and trunk kidney of rainbow trout (Salmo gairdneri).

D. Buhler, R. Lorenzana, O. Hedstrom, 1988, Toxicology and applied pharmacology.

The in vitro biotransformation of 2-aminofluorene in the visceral mass of the Pacific oyster, Crassostrea gigas.

D. Buhler, D. Schlenk, 1990, Xenobiotica; the fate of foreign compounds in biological systems.

Comparative effects of antioxidants on the toxicity of mixed pyrrolizidine alkaloids from Senecio jacobaea in mice.

J. A. Schmitz, C. Miranda, D. Buhler, 1982, Journal of toxicology and environmental health.

Mechanisms for pyrrolizidine alkaloid activation and detoxification.

C. Miranda, D. Buhler, B. Kedzierski, 1991, Advances in experimental medicine and biology.

Modifications of chronic hepatotoxicity of pyrrolizidine (Senecio) alkaloids by butylated hydroxyanisole and cysteine.

J. A. Schmitz, H. Ramsdell, C. Miranda, 1982, Toxicology letters.

Expression of a constitutive cytochrome P450 (CYP2K1) in livers of rainbow trout (Oncorhynchus mykiss) embryo and sac-fry

C. Miranda, D. Buhler, Yea-Huey Yang, 1997 .

Assessment of the State of Hepatic Monooxygenase Activity in Laboratory and Feral Fish

D. Buhler, J. Lech, M. Melancon, 1986, OCEANS '86.

Immuno-detection of proteins by cytochrome P450 antibodies in five species of sea anemones

D. Buhler, J. Stegeman, G. Winston, 1996 .

5.5 – Benzonitrile

D. Buhler, Jun-Lan Wang, 1990 .

Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore.

J. F. Stevens, C. Miranda, D. Buhler, 2003, Chemical Research in Toxicology.

AbstractThe regiospecific hydroxylation of lauric acid by rainbow trout cytochrome P450s

C. Miranda, D. Buhler, M. Henderson, 1996 .

Nitrogen and phosphorus solvents

D. Buhler, D. J. Reed, 1990 .