Martin Franke

发表

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

A. Visel, J. Opitz, D. Horn, 2015, Cell.

Formation of new chromatin domains determines pathogenicity of genomic duplications

S. Mundlos, M. Spielmann, M. Vingron, 2016, Nature.

Functional dissection of the Sox9–Kcnj2 locus identifies nonessential and instructive roles of TAD architecture

S. Mundlos, M. Vingron, L. Wittler, 2019, Nature Genetics.

Position effects at the FGF8 locus are associated with femoral hypoplasia.

S. Mundlos, M. Spielmann, M. Vingron, 2021, American journal of human genetics.

MiR-21 is required for efficient kidney regeneration in fish

M. Platzer, C. Englert, Martin Franke, 2015, BMC Developmental Biology.

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

Martin Vingron, Axel Visel, Simona Bianco, 2018, Nature Genetics.

Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus.

P. Robinson, S. Mundlos, M. Spielmann, 2012, American journal of human genetics.

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice.

Stefan Mundlos, Malte Spielmann, Guillaume Andrey, 2015, Cell reports.

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

A. Visel, S. Mundlos, M. Spielmann, 2018, Nature Genetics.

Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3

S. Mundlos, M. Spielmann, L. Wittler, 2022, bioRxiv.

Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism.

F. Faucz, J. Tena, C. Stratakis, 2022, American journal of human genetics.

CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression

J. Tena, Martin Franke, J. Gómez-Skarmeta, 2020, Nature Communications.

Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression

S. Mundlos, M. Vingron, L. Wittler, 2019, bioRxiv.

An evolutionary perspective of regulatory landscape dynamics in development and disease.

Martin Franke, J. Gómez-Skarmeta, 2018, Current opinion in cell biology.

Gain of gene regulatory network interconnectivity at the origin of vertebrates

J. Tena, Martin Franke, J. Gómez-Skarmeta, 2020, bioRxiv.

Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer

Joshua S. Clayton, S. Keleş, J. Harley, 2022, bioRxiv.