C. Zorumski

Y. Izumi, C. Zorumski, H. Katsuki, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Modulation of LTP induction by NMDA receptor activation and nitric oxide release.

Y. Izumi, C. Zorumski, 1998, Progress in brain research.

[25] - Assessment of Synaptic Effects of Nitric Oxide in Hippocampal Neurons

Y. Izumi, C. Zorumski, S. Mennerick, 1996 .

Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor

C. Zorumski, N. Bazan, L. Happel, 1992, Neuron.

Low concentrations of N-methyl-d-aspartate inhibit the induction of long-term potentiation in rat hippocampal slices

D. Clifford, Y. Izumi, C. Zorumski, 1992, Neuroscience Letters.

Nitric oxide inhibitors attenuate N-methyl-d-aspartate excitotoxicity in rat hippocampal slices

D. Clifford, Y. Izumi, C. Zorumski, 1992, Neuroscience Letters.

NMDA Receptors, mGluR5, and Endocannabinoids are Involved in a Cascade Leading to Hippocampal Long-Term Depression

Y. Izumi, C. Zorumski, 2012, Neuropsychopharmacology.

2-Amino-3-phosphonopropionate blocks the induction and maintenance of long-term potentiation in rat hippocampal slices

D. Clifford, Y. Izumi, C. Zorumski, 1991, Neuroscience Letters.

Direct Cortical Inputs Erase Long-Term Potentiation at Schaffer Collateral Synapses

Y. Izumi, C. Zorumski, Yukitoshi Izumi, 2008, The Journal of Neuroscience.

Modulation of hippocampal long-term potentiation by slow increases in ethanol concentration

Y. Izumi, C. Zorumski, K. Tokuda, 2007, Neuroscience.

Propofol Inhibits Long-term Potentiation but Not Long-term Depression in Rat Hippocampal Slices

Y. Izumi, C. Zorumski, K. Nagashima, 2005, Anesthesiology.

LTP in CA1 of the adult rat hippocampus and voltage‐activated calcium channels

Y. Izumi, C. Zorumski, 1998, Neuroreport.

Removal of extracellular calcium after conditioning stimulation disrupts long-term potentiation in the CA1 region of rat hippocampal slices

Y. Izumi, C. Zorumski, H. Katsuki, 1997, Neuroscience.

Developmental changes in the effects of metabotropic glutamate receptor antagonists on CA1 long-term potentiation in rat hippocampal slices

Y. Izumi, C. Zorumski, 1994, Neuroscience Letters.

The effect of agonist concentration, membrane voltage and calcium on n-methyl-d-aspartate receptor desensitization

C. Zorumski, G. D. Clark, D. B. Cufford, 1990, Neuroscience.

Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation

Kunio Kato, C. Zorumski, N. Bazan, 1994, Nature.

Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists

Y. Izumi, C. Zorumski, A. Zarrin, 2000, Neuroscience.

Long‐term potentiation inhibition by low‐level N‐methyl‐D‐aspartate receptor activation involves calcineurin, nitric oxide, and p38 mitogen‐activated protein kinase

Y. Izumi, C. Zorumski, K. Tokuda, 2008, Hippocampus.

Contributions of space-clamp errors to apparent time-dependent loss of Mg2+ block induced by NMDA.

C. Zorumski, S. Mennerick, L. Eisenman, 2017, Journal of neurophysiology.

Endogenous 24S-hydroxycholesterol modulates NMDAR-mediated function in hippocampal slices.

Y. Izumi, C. Zorumski, S. Mennerick, 2016, Journal of neurophysiology.

Postsynaptic modulation of NMDA synaptic currents in rat hippocampal microcultures by paired‐pulse stimulation.

C. Zorumski, S. Mennerick, C. Zorumski, 1996, The Journal of physiology.

Paired‐pulse modulation of fast excitatory synaptic currents in microcultures of rat hippocampal neurons.

C. Zorumski, S. Mennerick, C F Zorumski, 1995, The Journal of physiology.

Rapid desensitization of glutamate receptors in vertebrate central neurons.

L. Trussell, G. Fischbach, C. Zorumski, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Homeostatic Effects of Depolarization on Ca2+ Influx, Synaptic Signaling, and Survival

K. Moulder, C. Zorumski, S. Mennerick, 2003, The Journal of Neuroscience.

Long‐term potentiation requires activation of calcium‐independent phospholipase A2

Y. Izumi, C. Zorumski, R. Gross, 1995, FEBS letters.

Cross talk between synaptic receptors mediates NMDA-induced suppression of inhibition.

C. Zorumski, S. Mennerick, M. Chisari, 2012, Journal of neurophysiology.

Neural activity and survival in the developing nervous system

C. Zorumski, S. Mennerick, 2000, Molecular Neurobiology.

Norepinephrine reverses N-methyl-d-aspartate-mediated inhibition of long-term potentiation in rat hippocampal slices

D. Clifford, Y. Izumi, C. Zorumski, 1992, Neuroscience Letters.

Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system

J. Olney, C. Zorumski, S. Mennerick, 2009, Neurobiology of Disease.

Experimentally Induced Mammalian Models of Glaucoma

Y. Izumi, C. Zorumski, M. Ishikawa, 2015, BioMed research international.

Ammonia-mediated LTP inhibition: Effects of NMDA receptor antagonists and l-carnitine

Y. Izumi, C. Zorumski, M. Izumi, 2005, Neurobiology of Disease.

Excitotoxicity of l-DOPA and 6-OH-DOPA: Implications for Parkinson's and Huntington's diseases

J. Olney, C. Zorumski, M. Price, 1990, Experimental Neurology.

11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors

J. Steinbach, C. Zorumski, S. Mennerick, 2014, Psychopharmacology.

Neurosteroid analogues. 15. A comparative study of the anesthetic and GABAergic actions of alphaxalone, Δ16-alphaxalone and their corresponding 17-carbonitrile analogues.

C. Zorumski, S. Mennerick, A. Evers, 2010, Bioorganic & medicinal chemistry letters.

Neurosteroid analogues. 4. The effect of methyl substitution at the C-5 and C-10 positions of neurosteroids on electrophysiological activity at GABAA receptors.

C. Zorumski, D. Covey, M. Han, 1996, Journal of medicinal chemistry.

Enantioselectivity of steroid-induced gamma-aminobutyric acidA receptor modulation and anesthesia.

C. Zorumski, A. Evers, D. Covey, 1996, Molecular pharmacology.

Neurosteroid Access to the GABAA Receptor

J. Steinbach, C. Zorumski, S. Mennerick, 2005, The Journal of Neuroscience.

Exploring Nitrous Oxide as Treatment of Mood Disorders: Basic Concepts.

C. Zorumski, C. Conway, P. Nagele, 2018, Journal of clinical psychopharmacology.

Neuroexcitatory actions of Tamiflu and its carboxylate metabolite

Y. Izumi, C. Zorumski, T. Narahashi, 2007, Neuroscience Letters.

Risk architecture of schizophrenia: the role of epigenetics

C. R. Cloninger, I. Zwir, C. Zorumski, 2013, Current opinion in psychiatry.

A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression

C. N. Lessov-Schlaggar, B. Palanca, C. Zorumski, 2021, Science Translational Medicine.

Locally-generated Acetaldehyde Contributes to the Effects of Ethanol on Neurosteroids and LTP in the Hippocampus.

Y. Izumi, C. Zorumski, K. Tokuda, 2013, Neurology and clinical neuroscience.

The immediate early gene early growth response gene 3 mediates adaptation to stress and novelty

M. P. Howell, J. Milbrandt, L. Muglia, 2007, Neuroscience.

Locally‐generated acetaldehyde contributes to the effects of ethanol on neurosteroids and long‐term potentiation in the hippocampus

Y. Izumi, C. Zorumski, K. Tokuda, 2013 .

Locally-generated acetaldehyde is involved in ethanol-mediated LTP inhibition in the hippocampus

Y. Izumi, C. Zorumski, K. Tokuda, 2013, Neuroscience Letters.

Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices ex vivo and 24S-Hydroxycholesterol Levels in Mice in vivo

Y. Izumi, C. Zorumski, S. Mennerick, 2020, Frontiers in Molecular Neuroscience.

Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis

M. Quirk, S. Paul, L. Piccio, 2018, The Journal of Neuroscience.

Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits.

John W. Olney, Krikor Dikranian, J. Olney, 2003 .

Substrate Turnover by Transporters Curtails Synaptic Glutamate Transients

K. Isenberg, C. Zorumski, S. Mennerick, 1999, The Journal of Neuroscience.

Nitrous Oxide for Treatment-Resistant Major Depression: A Proof-of-Concept Trial

J. Miller, C. Zorumski, C. Conway, 2015, Biological Psychiatry.

Effects of acutely elevated hydrostatic pressure in a rat ex vivo retinal preparation.

Y. Izumi, C. Zorumski, M. Ishikawa, 2010, Investigative ophthalmology & visual science.

Calcium-dependent, slow desensitization distinguishes different types of glutamate receptors

G. Fischbach, C. Zorumski, J. Yang, 1989, Cellular and Molecular Neurobiology.

Steroid Inhibition of Rat Neuronal Nicotinic α4β2 Receptors Expressed in HEK 293 Cells

J. Steinbach, C. Zorumski, K. Paradiso, 2000 .

Steroid inhibition of rat neuronal nicotinic alpha4beta2 receptors expressed in HEK 293 cells.

J. Steinbach, C. Zorumski, K. Paradiso, 2000, Molecular Pharmacology.

A Synthetic 18-Norsteroid Distinguishes between Two Neuroactive Steroid Binding Sites on GABAA Receptors

J. Steinbach, C. Zorumski, S. Mennerick, 2010, Journal of Pharmacology and Experimental Therapeutics.

A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons

David E Reichert, C. Zorumski, S. Mennerick, 2016, Scientific Reports.

Different actions of a short-acting barbiturate on sodium and potassium conductances in invertebrate and vertebrate neurons

C. Zorumski, J. Yang, J. Johansen, 1989, Neuropharmacology.

The influence of the membrane on neurosteroid actions at GABAA receptors

Steven Mennerick, J. Steinbach, C. Zorumski, 2009, Psychoneuroendocrinology.

Effects on membrane capacitance of steroids with antagonist properties at GABAA receptors.

C. Zorumski, S. Mennerick, L. Eisenman, 2008, Biophysical journal.

Volatile anesthetics gate a chloride current in postnatal rat hippocampal neurons

K. Isenberg, C. Zorumski, Jay Yang, 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Motivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice

D. Gutmann, Y. Izumi, C. Zorumski, 2013, PloS one.

INVOLVEMENT OF ILLUMINATION IN INDOCYANINE GREEN TOXICITY AFTER ITS WASHOUT IN THE EX VIVO RAT RETINA

Y. Izumi, C. Zorumski, Yukitoshi Izumi, 2009, Retina.

Neuronal Expression of the Glutamate Transporter GLT-1 in Hippocampal Microcultures

K. Isenberg, J. Rothstein, R. Dhond, 1998, The Journal of Neuroscience.

A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

J. Olney, C. Zorumski, Kelvin A. Yamada, 1993, Neuron.

Acute Vigabatrin Retinotoxicity in Albino Rats Depends on Light But Not GABA

Y. Izumi, C. Zorumski, M. Izumi, 2004, Epilepsia.

Slow Death of Postnatal Hippocampal Neurons by GABAA Receptor Overactivation

K. Isenberg, C. Zorumski, S. Mennerick, 2000, The Journal of Neuroscience.

A tribute to Lee Nelken Robins: from colleagues and friends

M. Rutter, P. Bebbington, F. Earls, 2010, Social Psychiatry and Psychiatric Epidemiology.

Quantification of bursting and synchrony in cultured hippocampal neurons.

Steven Mennerick, C. Zorumski, S. Mennerick, 2015, Journal of neurophysiology.

Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy

C. Zorumski, S. Mennerick, C. Conway, 2015, Front. Psychiatry.

Non-competitive inhibition of GABA currents by phenothiazines in cultured chick spinal cord and rat hippocampal neurons

C. Zorumski, J. Yang, 1988, Neuroscience Letters.

ECT-Induced Interictal Delirium in Patients With a History of a CVA

G. Figiel, C. Zorumski, G. Mattingly, 1992, Journal of geriatric psychiatry and neurology.

24(S)-Hydroxycholesterol as a Modulator of Neuronal Signaling and Survival

Y. Izumi, C. Zorumski, S. Mennerick, 2016, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond

S. Paul, C. Zorumski, S. Mennerick, 2019, Neurobiology of Stress.

Psychiatric Education in an Era of Rapidly Occurring Scientific Advances

E. Rubin, C. Zorumski, 2003, Academic medicine : journal of the Association of American Medical Colleges.

More About the Future of Psychiatry Education

E. Rubin, C. Zorumski, 2012 .

Perspective: Upcoming paradigm shifts for psychiatry in clinical care, research, and education.

E. Rubin, C. Zorumski, 2012, Academic medicine : journal of the Association of American Medical Colleges.

Nitrous Oxide (Laughing Gas) Facilitates Excitability in Rat Hippocampal Slices through γ-Aminobutyric Acid A Receptor-mediated Disinhibition

Y. Izumi, C. Zorumski, K. Nagashima, 2005, Anesthesiology.

Glaucoma and microglia-induced neuroinflammation

T. Nakazawa, Y. Izumi, C. Zorumski, 2023, Frontiers in Ophthalmology.

Short-term environmental enrichment enhances synaptic plasticity in hippocampal slices from aged rats

Y. Izumi, C. Zorumski, L. Stein, 2016, Neuroscience.

Neurosteroids and oxysterols as potential therapeutic agents for glaucoma and Alzheimer's disease.

Y. Izumi, C. Zorumski, D. Covey, 2018, Neuropsychiatry.

Acute and Chronic Neurodegenerative Disorders Produced by Dietary Excitotoxins

J. Olney, C. Zorumski, 1992 .

The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy

Y. Izumi, C. Zorumski, H. Kunikata, 2022, Frontiers in Pharmacology.

The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models

Y. Izumi, C. Zorumski, D. Covey, 2020, Autophagy.

Neurosteroids are endogenous neuroprotectants in an ex vivo glaucoma model.

Y. Izumi, C. Zorumski, M. Ishikawa, 2014, Investigative ophthalmology & visual science.

Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA‐A receptor potentiation

J. Steinbach, C. Zorumski, S. Mennerick, 2007, The Journal of physiology.

Acute and chronic effects of ethanol on learning-related synaptic plasticity.

Y. Izumi, C. Zorumski, S. Mennerick, 2014, Alcohol.

Neuregulin and Dopamine D4 Receptors Contribute Independently to Depotentiation of Schaffer Collateral LTP by Temperoammonic Path Stimulation

Y. Izumi, C. Zorumski, 2017, eNeuro.

Pharmacological Aspects of NMDA Receptors, mGluR5, and Endocannabinoids

Y. Izumi, C. Zorumski, 2017 .

Basal levels of adenosine modulate mGluR5 on rat hippocampal astrocytes

C. Zorumski, S. Mennerick, R. Cormier, 2001, Glia.

Norepinephrine promotes long‐term potentiation in the adult rat hippocampus in vitro

Y. Izumi, C. Zorumski, 1999, Synapse.

The role of T‐type calcium channels in the subiculum: to burst or not to burst?

Y. Izumi, C. Zorumski, V. Jevtovic-Todorovic, 2017, The Journal of physiology.

Hippocampal Neurons to Paired-Pulse Synaptic Depression in Cultured Channel Inactivation + Contribution of Presynaptic Na

D. Debanne, E. Campanac, Andrzej Bialowas, 2015 .

Contribution of presynaptic Na(+) channel inactivation to paired-pulse synaptic depression in cultured hippocampal neurons.

C. Zorumski, S. Mennerick, Yejun He, 2002, Journal of neurophysiology.

Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices

Y. Izumi, C. Zorumski, H. Katsuki, 1997, Neuroscience Letters.

SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids

E. Lenze, Y. Izumi, C. Zorumski, 2023, Translational Psychiatry.

NMDA receptors and metaplasticity: Mechanisms and possible roles in neuropsychiatric disorders

Y. Izumi, C. Zorumski, 2012, Neuroscience & Biobehavioral Reviews.

Slow Actions of Neuroactive Steroids at GABAA Receptors

Deepani Jinadasa, Steven Mennerick, C. Zorumski, 2004, The Journal of Neuroscience.

A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol

S. Paul, A. Cashikar, Y. Izumi, 2021, The Journal of Neuroscience.

Ethanol Enhances Neurosteroidogenesis in Hippocampal Pyramidal Neurons by Paradoxical NMDA Receptor Activation

Y. Izumi, C. Zorumski, K. Tokuda, 2011, The Journal of Neuroscience.

Opportunities for Drug Repurposing of Serotonin Reuptake Inhibitors: Potential Uses in Inflammation, Infection, Cancer, Neuroprotection, and Alzheimer’s Disease Prevention

E. Lenze, C. Zorumski, J. Cirrito, 2021, Pharmacopsychiatry.

Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis

Y. Izumi, C. Zorumski, K. O’Dell, 2010, The Journal of Neuroscience.

24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure

Y. Izumi, C. Zorumski, M. Ishikawa, 2016, Scientific Reports.

Trial of SAGE-217 in Patients with Major Depressive Disorder.

D. Rubinow, H. Gunduz-Bruce, C. Zorumski, 2019, The New England journal of medicine.

Endogenous Monocarboxylates Sustain Hippocampal Synaptic Function and Morphological Integrity during Energy Deprivation

Y. Izumi, C. Zorumski, H. Katsuki, 1997, The Journal of Neuroscience.

Novel neurosteroid hypnotic blocks T‐type calcium channel‐dependent rebound burst firing and suppresses long‐term potentiation in the rat subiculum

Y. Izumi, C. Zorumski, V. Jevtovic-Todorovic, 2019, British journal of anaesthesia.

Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function

Y. Izumi, C. Zorumski, 2014, Neuropharmacology.

Enantioselective blockade of T-type Ca2+ current in adult rat sensory neurons by a steroid that lacks gamma-aminobutyric acid-modulatory activity.

C. Lingle, C. Zorumski, M. Prakriya, 1998, Molecular pharmacology.

Prospective uses of ECT in the presence of intracranial tumors.

G. Figiel, C. Zorumski, G. Mattingly, 1991, The Journal of neuropsychiatry and clinical neurosciences.

Neuroprotective effects of pyruvate following NMDA-mediated excitotoxic insults in hippocampal slices

Y. Izumi, C. Zorumski, 2010, Neuroscience Letters.

Lactate dehydrogenase release is facilitated by brief sonication of rat hippocampal slices and isolated retinas following acute neuronal damage

Y. Izumi, C. Zorumski, M. Izumi, 2001, Journal of Neuroscience Methods.

Müller cell swelling, glutamate uptake, and excitotoxic neurodegeneration in the isolated rat retina

J. Olney, Y. Izumi, C. Zorumski, 1999, Glia.

b-Hydroxybutyrate Fuels Synaptic Function during Development Histological and Physiological Evidence in Rat Hippocampal Slices

Y. Izumi, C. Zorumski, H. Katsuki, 1998 .

Nitric oxide inhibitors attenuate ischemic degeneration in the CA1 region of rat hippocampal slices

D. Clifford, Y. Izumi, C. Zorumski, 1996, Neuroscience Letters.

Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors.

C. Zorumski, S. Mennerick, A. Evers, 2004, Molecular pharmacology.

Selective Antagonism of 5-Reduced Neurosteroid Effects at GABAA Receptors

C. Zorumski, S. Mennerick, A. Evers, 2004 .

Ca(v)3.2 channel is a molecular substrate for inhibition of T-type calcium currents in rat sensory neurons by nitrous oxide.

C. Zorumski, S. Mennerick, V. Jevtovic-Todorovic, 2001, Molecular pharmacology.

Redox Modulation of T-Type Calcium Channels in Rat Peripheral Nociceptors

J. Olney, C. Zorumski, S. Mennerick, 2001, Neuron.

Neurosteroid enantiomers as potentially novel neurotherapeutics

Y. Izumi, C. Zorumski, S. Mennerick, 2023, Neuroscience & Biobehavioral Reviews.

Functional reduction of SK3-mediated currents precedes AMPA-receptor-mediated excitotoxicity in dopaminergic neurons

D. G. Herrera, C. Zorumski, D. Mascó, 2011, Neuropharmacology.

Excitotoxicity Triggered by Neurobasal Culture Medium

C. Zorumski, S. Mennerick, Devon C. Crawford, 2011, PloS one.

A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

C. Zorumski, S. Mennerick, D. Covey, 2018, Front. Neurosci..

Inhibitors of cellular stress overcome acute effects of ethanol on hippocampal plasticity and learning

Y. Izumi, C. Zorumski, 2020, Neurobiology of Disease.

Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel

S. Paul, C. Zorumski, S. Mennerick, 2015, British journal of pharmacology.

Ethanol-Induced Death of Postnatal Hippocampal Neurons

K. Moulder, K. Isenberg, C. Zorumski, 2002, Neurobiology of Disease.

Expression of fructose sensitive glucose transporter in the brains of fructose-fed rats

K. Isenberg, C. Zorumski, R. Cormier, 2006, Neuroscience.

Overlapping symptoms of geriatric depression and Alzheimer-type dementia.

E. Rubin, W. Burke, C. Zorumski, 1988, Hospital & community psychiatry.

Sensitivity of N-Methyl-d-Aspartate Receptor–Mediated Excitatory Postsynaptic Potentials and Synaptic Plasticity to TCN 201 and TCN 213 in Rat Hippocampal Slices

Y. Izumi, C. Zorumski, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Passive and synaptic properties of hippocampal neurons grown in microcultures and in mass cultures.

C. Zorumski, S. Mennerick, A. Benz, 1995, Journal of neurophysiology.

Allopregnanolone Effects on Inhibition in Hippocampal Parvalbumin Interneurons

C. Zorumski, S. Mennerick, Xinguo Lu, 2023, eNeuro.

Lack of Neurosteroid Selectivity at δ vs. γ2-Containing GABAA Receptors in Dentate Granule Neurons

C. Zorumski, S. Mennerick, Xinguo Lu, 2020, Frontiers in Molecular Neuroscience.

Chemogenetic Isolation Reveals Synaptic Contribution of δ GABAA Receptors in Mouse Dentate Granule Neurons

J. Steinbach, C. Zorumski, S. Mennerick, 2018, The Journal of Neuroscience.

5β-Reduced Neuroactive Steroids Are Novel Voltage-Dependent Blockers of T-Type Ca2+ Channels in Rat Sensory Neurons in Vitro and Potent Peripheral Analgesics in Vivo

C. Zorumski, V. Jevtovic-Todorovic, S. Todorovic, 2004, Molecular Pharmacology.

ECT-induced delirium in depressed patients with Parkinson's disease.

K. Krishnan, P. Doraiswamy, Deborah S. Smith, 1991, The Journal of neuropsychiatry and clinical neurosciences.

Blockade of ionotropic quisqualate receptor desensitization in rat hippocampal neurons by wheatgerm agglutinin and other lectins

D. Clifford, C. Zorumski, L. Thio, 1993, Neuroscience.

Complex responses activated by ibotenate in postnatal rat hippocampal neurons

D. Clifford, R. Todd, C. Zorumski, 1989, Brain Research.

Calcium influx through N-methyl-d-aspartate channels activates a potassium current in postnatal rat hippocampal neurons

D. Clifford, C. Zorumski, L. Thio, 1989, Neuroscience Letters.

Excitotoxicity and Neurodegenerative Disorders

J. Olney, C. Zorumski, 1992 .

Acute Symptoms of Mild to Moderate COVID-19 Are Highly Heterogeneous Across Individuals and Over Time

J. Miller, J. Piccirillo, T. Rodebaugh, 2021, Open forum infectious diseases.

Effects of medazepam on voltage-gated ion currents of cultured chick sensory neurons.

C. Zorumski, J. Yang, R. Delorenzo, 1987, European journal of pharmacology.

A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition

C. Zorumski, S. Mennerick, K. Krishnan, 2016, Neuropharmacology.

Electrophysiological properties of identified postnatal rat hippocampal pyramidal neurons in primary culture.

D. Clifford, C. Zorumski, J. Yang, 1993, Brain research. Developmental brain research.

Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons

D. Clifford, C. Zorumski, L. Thio, 1990, Neuron.

Measurement of glial transport currents in microcultures: application to excitatory neurotransmission.

C. Zorumski, S. Mennerick, 1998, Methods in enzymology.

Sex Differences in the Role of CNIH3 on Spatial Memory and Synaptic Plasticity

Sidney B. Williams, Terrance T. Kummer, E. Nelson, 2021, Biological Psychiatry.

Functional mapping of limbic seizures originating in the hippocampus: a combined 2-deoxyglucose and electrophysiologic study

C. Zorumski, E. Lothman, E. W. Lothman, 1985, Brain Research.

24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation

C. Zorumski, S. Mennerick, Min-Yu Sun, 2017, PloS one.

Platelet-activating factor as a potential retrograde messenger.

C. Zorumski, K. Kato, 1996, Journal of lipid mediators and cell signalling.

Activation‐Dependent Properties of Pregnenolone Sulfate Inhibition of GABAA Receptor‐Mediated Current

C. Zorumski, S. Mennerick, L. Eisenman, 2003, The Journal of physiology.

Elevated potassium shortens action potential duration by altering outward currents in chick dorsal root ganglia neurons.

C. Zorumski, J. Yang, 1990, Journal of neurobiology.

GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic Inputs

Y. Izumi, C. Zorumski, 2016, PloS one.

Effects of neurosteroid 3α-hydroxy-5α-pregnan-20-one on ethanol-mediated paired-pulse depression of population spikes in the CA1 region of rat hippocampal slices

Y. Izumi, C. Zorumski, K. Murayama, 2006, Neuroscience Letters.

Kindling with rapidly recurring hippocampal seizures

J. Perlin, C. Zorumski, E. Lothman, 1985, Brain Research.

Physiological markers of rapid antidepressant effects of allopregnanolone

C. Zorumski, S. Mennerick, Xinguo Lu, 2021, Journal of neuroendocrinology.

GABAergic neurosteroids mediate the effects of ethanol on long‐term potentiation in rat hippocampal slices

Y. Izumi, C. Zorumski, K. Krishnan, 2007, The European journal of neuroscience.

Developmental changes in long‐term potentiation in CA1 of rat hippocampal slices

Y. Izumi, C. Zorumski, 1995, Synapse.

Effect of electrical parameters on ECT convulsive threshold and duration.

S. Dinwiddie, E. Spitznagel, K. Isenberg, 2016, Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists.

Psychopathology in the genome and neuroscience era

E. Rubin, C. Zorumski, 2005 .

JAMA Psychiatry: Best of 2019.

C. Zorumski, 2020, JAMA psychiatry.

Maintenance electroconvulsive therapy in schizophrenia.

J. Hudziak, G. Figiel, C. Zorumski, 1994, Journal of Clinical Psychiatry.

Enantioselective modulation of GABAergic synaptic transmission by steroids and benz[e]indenes in hippocampal microcultures

C. Zorumski, S. Mennerick, D. Covey, 1998, Synapse.

Nampt is required for long-term depression and the function of GluN2B subunit-containing NMDA receptors

Y. Izumi, C. Zorumski, S. Imai, 2015, Brain Research Bulletin.

Characteristics of concatemeric GABAA receptors containing α4/δ subunits expressed in Xenopus oocytes

J. Steinbach, C. Zorumski, S. Mennerick, 2012, British journal of pharmacology.

Striatal mGlu5-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways

Y. Izumi, C. Zorumski, K. O’Malley, 2023, The Journal of biological chemistry.

The role of platelet-activating factor in the release of excitotoxic neurotransmitters

C. Zorumski, N. Bazan, L. Happel, 1994 .

Noncompetitive, Voltage-Dependent NMDA Receptor Antagonism by Hydrophobic Anions

C. Zorumski, S. Mennerick, M. Chisari, 2013, Molecular Pharmacology.

Modulation of long-term potentiation induction in the hippocampus by N-methyl-d-aspartate-mediated presynaptic inhibition

C. Zorumski, K. Kato, S.-T Li, 1999, Neuroscience.

ECT in primary and secondary depression.

T. Reich, W. Burke, C. Zorumski, 1986, The Journal of clinical psychiatry.

Persistent Brain Connectivity Changes in Healthy Volunteers Following Nitrous Oxide Inhalation

Broc A. Burke, T. Zeffiro, C. Zorumski, 2023, Biological Psychiatry Global Open Science.

11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors

J. Steinbach, C. Zorumski, S. Mennerick, 2014, Psychopharmacology.

The herbicide glyphosate inhibits hippocampal long-term potentiation and learning through activation of pro-inflammatory signaling

Y. Izumi, C. Zorumski, K. O’Dell, 2023, Research square.

Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity.

C. Zorumski, S. Mennerick, A. Evers, 2011, Journal of Medicinal Chemistry.

Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light

J. Steinbach, C. Zorumski, S. Mennerick, 2007, Nature Neuroscience.

Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes.

C. Zorumski, S. Mennerick, A. Evers, 2006, Journal of medicinal chemistry.

Effects on gamma-aminobutyric acid (GABA)(A) receptors of a neuroactive steroid that negatively modulates glutamate neurotransmission and augments GABA neurotransmission.

W. Shen, C. Zorumski, S. Mennerick, 2001, Molecular pharmacology.

Enantioselectivity of Pregnanolone-Induced γ-Aminobutyric AcidA Receptor Modulation and Anesthesia

C. Zorumski, A. Evers, D. Covey, 2000 .

Neurosteroid Analogues. Part 5. Enantiomers of Neuroactive Steroids and Benz[e]indenes: Total Synthesis, Electrophysiological Effects on GABAA Receptor Function and Anesthetic Actions in Tadpoles.

C. Zorumski, A. Evers, D. Covey, 1998 .

Effects of Neurosteroid and Benz[e]indene Enantiomers on GABAA Receptors in Cultured Hippocampal Neurons and Transfected HEK-293 Cells

K. Isenberg, C. Zorumski, D. Covey, 1996, Neuropharmacology.

Neurosteroid Analogues. Part 3. The Synthesis and Electrophysiological Evaluation of Benz(e)indene Congeners of Neuroactive Steroids Having the 5β‐Configuration.

C. Zorumski, D. Covey, M. Han, 1996 .

Neurosteroid analogues. 3. The synthesis and electrophysiological evaluation of benz[e]indene congeners of neuroactive steroids having the 5 beta-configuration.

C. Zorumski, D. Covey, M. Han, 1995, Journal of medicinal chemistry.

Neurosteroid analogues: structure-activity studies of benz[e]indene modulators of GABAA receptor function. 1. The effect of 6-methyl substitution on the electrophysiological activity of 7-substituted benz[e]indene-3-carbonitriles.

C. Zorumski, D. Covey, Y. Hu, 1993, Journal of Medicinal Chemistry.

Modulation of GABAA receptor function by benz[e]indenes and phenanthrenes.

K. Isenberg, C. Zorumski, D. Covey, 1993, Journal of medicinal chemistry.

Effects of a benz[e]indene on gamma-aminobutyric acid-gated chloride currents in cultured postnatal rat hippocampal neurons.

K. Isenberg, C. Zorumski, D. Covey, 1992, Molecular pharmacology.

Neurosteroid analogues. Part 5.1 Enantiomers of neuroactive steroids and benz[e]indenes: total synthesis, electrophysiological effects on GABAA receptor function and anesthetic actions in tadpoles

C. Zorumski, A. Evers, D. Covey, 1997 .

Molecular Neurosteroid Access to the GABAA Receptor

J. Steinbach, C. Zorumski, S. Mennerick, 2005 .

Chronic pain. A pharmacologic review and behavior modification approach.

G. Bakris, C. Zorumski, 1983, Postgraduate medicine.

Temperoammonic Stimulation Depotentiates Schaffer Collateral LTP via p38 MAPK Downstream of Adenosine A1 Receptors

Y. Izumi, C. Zorumski, 2019, The Journal of Neuroscience.

Demystifying Psychiatry: A Resource for Patients and Families

C. Zorumski, 2009 .

Glutamate as a Neurotransmitter

C. Zorumski, S. Mennerick, 2020, eLS.

Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model

Y. Izumi, C. Zorumski, D. Covey, 2018, Scientific Reports.

Concanavalin a enhances excitatory synaptic transmission in cultured rat hippocampal neurons

C. Zorumski, L. Thio, D. Clifford, 1993, Synapse.

Blockade of ionotropic quisqualate receptor desensitization by wheat germ agglutinin in cultured postnatal rat hippocampal neurons.

D. Clifford, C. Zorumski, L. Thio, 1992, Journal of neurophysiology.

NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue

C. Zorumski, S. Mennerick, L. Eisenman, 2009, The Journal of physiology.

α-Substituted thiobutyrolactones potentiate GABA currents in voltage-clamped chick spinal cord neurons

D. Clifford, C. Zorumski, J. Yang, 1988, Neuroscience Letters.

Trifluoperazine blocks GABA-gated chloride currents in cultured chick spinal cord neurons.

C. Zorumski, J. Yang, 1989, Journal of neurophysiology.

The STOP COVID 2 Study: Fluvoxamine vs Placebo for Outpatients With Symptomatic COVID-19, a Fully Remote Randomized Controlled Trial

M. Rich, J. Schiffer, D. Boulware, 2023, Open forum infectious diseases.

Cyclodextrins sequester neuroactive steroids and differentiate mechanisms that rate limit steroid actions

C. Zorumski, S. Mennerick, D. Covey, 2007, British journal of pharmacology.

Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.

C. Zorumski, S. Mennerick, A. Evers, 2005, Journal of medicinal chemistry.

A spontaneous tonic chloride conductance in solitary glutamatergic hippocampal neurons

C. Zorumski, S. Mennerick, G. Kress, 2006, Brain Research.

Trial of SAGE-217 in Patients with Major Depressive Disorder. Reply.

H. Gunduz-Bruce, C. Zorumski, S. Kanes, 2019, The New England journal of medicine.

Precision Neuroimaging for Localization-Related Psychiatry.

Timothy O. Laumann, N. Dosenbach, C. Zorumski, 2023, JAMA psychiatry.

Success Rates in Psychiatry.

K. Freedland, C. Zorumski, 2023, JAMA psychiatry.

Dissection method affects electrophysiological properties of hippocampal slices.

Y. Izumi, C. Zorumski, L. Stein, 2017, Oruen : the CNS journal.

Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors.

David E Reichert, J. Steinbach, C. Zorumski, 2012, Journal of medicinal chemistry.

Nitrous Oxide for Treatment-Resistant Major Depression: A Proof-of-Concept Trial

C. Zorumski, P. Nagele, A. Duma, 2015, Biological Psychiatry.

L-cysteine, a bicarbonate-sensitive endogenous excitotoxin.

J. Olney, C. Zorumski, M. Price, 1990, Science.

The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-d-Aspartate Receptors

Gabriel M. Belfort, S. Paul, A. Robichaud, 2013, The Journal of Neuroscience.

Guest Editorial: Treatment Choices When Options Appear Plentiful

K. Isenberg, C. Zorumski, 2006 .

Cross talk between synaptic receptors mediates NMDA-induced suppression of inhibition.

C. Zorumski, S. Mennerick, M. Chisari, 2012, Journal of neurophysiology.

Complex responses activated by ibotenate in postnatal rat hippocampal neurons

D. Clifford, R. Todd, C. Zorumski, 1989, Brain Research.

Chronic pain and tricyclic antidepressants.

E. Rubin, C. Zorumski, 1981, Annals of internal medicine.

Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule‐associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1

Y. Izumi, C. Zorumski, L. Stein, 2017, Brain and behavior.

Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis

Y. Izumi, C. Zorumski, K. Tokuda, 2010, The Journal of Neuroscience.

Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function

Y. Izumi, C. Zorumski, 2014, Neuropharmacology.

"What Were You Before the War?" Repurposing Psychiatry During the COVID-19 Pandemic.

E. Lenze, C. Zorumski, J. Karp, 2020, The Journal of clinical psychiatry.

A role for δ subunit-containing GABAA receptors on parvalbumin positive neurons in maintaining electrocortical signatures of sleep states

C. Zorumski, S. Mennerick, N. Rensing, 2024, bioRxiv.

Neurosteroid enantiomers as potentially novel neurotherapeutics

Y. Izumi, C. Zorumski, S. Mennerick, 2023, Neuroscience & Biobehavioral Reviews.

Neurosteroid Enantiomers as Potentially Novel NeurotherapeuticsNeurosteroid enantiomers

Y. Izumi, C. Zorumski, A. Evers, 2023 .

A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition

C. Zorumski, S. Mennerick, K. Krishnan, 2016, Neuropharmacology.