P. Hoffman

发表

Chronic exposure of cerebellar granule cells to ethanol results in increased N-methyl-D-aspartate receptor function.

K. Iorio, L. Reinlib, B. Tabakoff, 1992, Molecular pharmacology.

Phosphatidylinositol 3′‐OH kinase and protein kinase A pathways mediate the anti‐apoptotic effect of pituitary adenylyl cyclase‐activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol

P. Hoffman, Sanjiv V. Bhave, 2003, Journal of neurochemistry.

Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse

Brian E. Vestal, Pamela H. Russell, B. Tabakoff, 2018, BMC Genomics.

Whole Brain and Brain Regional Coexpression Network Interactions Associated with Predisposition to Alcohol Consumption

B. Tabakoff, P. Hoffman, M. Miles, 2013, PloS one.

Chapter 6 – Central Nervous System Effects of Neurohypophyseal Peptides*

P. Hoffman, 1987 .

Genetical genomic determinants of alcohol consumption in rats and humans

G. Koob, J. Whitfield, B. Grant, 2009, BMC Biology.

Genetics of gene expression characterizes response to selective breeding for alcohol preference

N. Grahame, B. Tabakoff, P. Hoffman, 2014, Genes, brain, and behavior.

Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 maintain functional tolerance to ethanol.

P. Hoffman, G. Szabó, 1995, European journal of pharmacology.

Effects of Alcohol on Excitatory Amino Acid Receptor Function

P. Hoffman, 1995 .

Platelet MAO Activity in Type I and Type II Alcoholism a

C. Robert Cloninger, B. Tabakoff, P. Hoffman, 1994, Annals of the New York Academy of Sciences.

NMDA Receptors: Role in Ethanol Withdrawal Seizures

K. Grant, L. Snell, K. Iorio, 1992, Annals of the New York Academy of Sciences.

A genetic study of platelet adenylate cyclase activity: evidence for a single major locus effect in fluoride-stimulated activity.

C. Robert Cloninger, B. Tabakoff, P. Hoffman, 1991, American journal of human genetics.

Human Brain Aldehyde Reductases: Relationship to Succinic Semialdehyde Reductase and Aldose Reductase

P. Hoffman, B. Wermuth, J. P. Wartburg, 1980, Journal of neurochemistry.

The contribution of voltage-gated and NMDA receptor-gated calcium channels to ethanol withdrawal seizures.

B. Tabakoff, P. Hoffman, 1991, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

Hippocampal and Cerebellar β‐Adrenergic Receptors and Adenylate Cyclase Are Differentially Altered by Chronic Ethanol Ingestion

B. Tabakoff, P. Hoffman, P. Valverius, 1989, Journal of neurochemistry.

Alcohol interactions with brain opiate receptors.

B. Tabakoff, P. Hoffman, 1983, Life sciences.

Controlling the “Opioid Epidemic”: A Novel Chemical Entity (NCE) to Reduce or Supplant Opiate Use for Chronic Pain

B. Tabakoff, P. Hoffman, 2020, Journal of psychiatry and brain science.

The sequenced rat brain transcriptome – its use in identifying networks predisposing alcohol consumption

G. Koob, Y. Israel, B. Tabakoff, 2015, The FEBS journal.

Alcohol Addiction: An Enigma among Us

B. Tabakoff, P. Hoffman, 1996, Neuron.

Association of monoamine oxidase (MAO) activity with alcoholism and alcoholic subtypes.

C. Robert Cloninger, B. Tabakoff, P. Hoffman, 1993, American journal of medical genetics.

Receptor-mediated dopaminergic function after ethanol withdrawal.

B. Tabakoff, P. Hoffman, R. Black, 1980, Alcoholism, clinical and experimental research.

L. B. Flexner, J. B. Flexner, P. Hoffman, 1978, Pharmacology Biochemistry and Behavior.

The Marriage of Phenomics and Genetical Genomics: A Systems Approach to Complex Trait Analysis

L. Hunter, B. Tabakoff, P. Hoffman, 2010 .

Platelet adenylyl cyclase activity in alcoholics and subtypes of alcoholics. WHO/ISBRA Study Clinical Centers.

C. Robert Cloninger, R. Todd, B. Tabakoff, 1996, Alcoholism, clinical and experimental research.

Gene Expression in Animals with Different Acute Responses to Ethanol

B. Tabakoff, P. Hoffman, 2005, Addiction biology.

Effects of alcohol and acetate on cerebral blood flow: a pilotstudy

B. Tabakoff, P. Hoffman, Brianne Sutton, 2020 .

Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains.

B. Tabakoff, P. Hoffman, P. Flodman, 2014, Alcoholism, clinical and experimental research.

DIAGNOSTIC GENETIQUE DE DEPRESSION

B. Tabakoff, P. Hoffman, L. Saba, 2004 .

Chronic tolerance to ethanol in the N:NIH rat.

K. Grant, B. Tabakoff, P. Hoffman, 1989, Alcoholism, clinical and experimental research.

Platelet adenylyl cyclase activity as a trait marker of alcohol dependence. WHO/ISBRA Collaborative Study Investigators. International Society for Biomedical Research on Alcoholism.

J. Whitfield, B. Grant, J. Saunders, 2000, Alcoholism, clinical and experimental research.

Monoamine oxidases and alcoholism. I. Studies in unrelated alcoholics and normal controls.

C. Robert Cloninger, B. Suarez, B. Tabakoff, 1995, American journal of medical genetics.

Type 7 Adenylyl Cyclase-Mediated Hypothalamic-Pituitary-Adrenal Axis Responsiveness: Influence of Ethanol and Sex

B. Tabakoff, P. Hoffman, L. Saba, 2010, Journal of Pharmacology and Experimental Therapeutics.

Ethanol fails to modify [3H]GR65630 binding to 5-HT3 receptors in NCB-20 cells and in rat cerebral membranes.

B. Tabakoff, P. Hoffman, K. Hellevuo, 1991, Alcoholism, clinical and experimental research.

Adenylyl cyclases and alcohol.

B. Tabakoff, P. Hoffman, 1998, Advances in second messenger and phosphoprotein research.

Adaptive changes in the dopamine system produced by chronic ethanol feeding.

B. Tabakoff, P. Hoffman, 1979, Drug and alcohol dependence.

Hypothalamic vasopressin mRNA levels in mice are decreased after chronic ethanol ingestion.

J. Dave, B. Tabakoff, P. Hoffman, 1990, European journal of pharmacology.

Acute and chronic effects of ethanol on receptor-mediated phosphatidylinositol 4,5-bisphosphate breakdown in mouse brain.

B. Tabakoff, P. Hoffman, G. Luthin, 1986, Molecular pharmacology.

Multiple aldehyde reductases of human brain.

P. Hoffman, B. Wermuth, J. von Wartburg, 1980, Advances in experimental medicine and biology.

Biological aspects of alcoholism

B. Tabakoff, P. Hoffman, N. Sartorius, 1994 .

Role of protein kinase C in ethanol-induced activation of adenylyl cyclase.

B. Tabakoff, P. Hoffman, E. Nelson, 1999, Alcoholism, clinical and experimental research.

Is ethanol a discriminating substance?

B. Tabakoff, P. Hoffman, A. McLaughlin, 1988, Seminars in liver disease.

Genetics and biological markers of risk for alcoholism.

B. Tabakoff, P. Hoffman, 1988, Public health reports.

Preparation of oxytocin specifically 14C‐labeled in the tyrosine residue

P. Hoffman, R. Walter, 1976, FEBS letters.

Time-dependency of neurohypophyseal peptide attenuation of puromycin amnesia in mice.

L. B. Flexner, J. B. Flexner, P. Hoffman, 2009, International journal of peptide and protein research.

Arginine vasopressin induces the expression of c-fos in the mouse septum and hippocampus.

J. Dave, B. Tabakoff, P. Hoffman, 1990, Brain research. Molecular brain research.

Reduction of arginine vasopressin binding sites in mouse lateral septum by treatment with 6-hydroxydopamine

B. Tabakoff, P. Hoffman, I. Mefford, 1990, Brain Research.

Receptors with V1 characteristics mediate the maintenance of ethanol tolerance by vasopressin.

B. Tabakoff, P. Hoffman, G. Szabó, 1988, The Journal of pharmacology and experimental therapeutics.

Forskolin promotes the development of ethanol tolerance in 6-hydroxydopamine-treated mice.

B. Tabakoff, P. Hoffman, G. Szabó, 1988, Life sciences.

Effect of an imidazobenzodiazepine, Ro15-4513, on the incoordination and hypothermia produced by ethanol and pentobarbital.

S. Paul, P. Suzdak, B. Tabakoff, 1987, Life sciences.

Vasopressin and Ethanol Tolerance: Postulated Mechanism for Neuroadaptation

J. Dave, B. Tabakoff, P. Hoffman, 1989 .

Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes

K. J. Lawrence, R. Harris, L. Snell, 2017, Scientific Reports.

The role of the type 7 adenylyl cyclase isoform in alcohol use disorder and depression

B. Tabakoff, P. Hoffman, 2022, Frontiers in Pharmacology.

NIAAA Publications

P. Hoffman, S. Bhave, P. Clapp, 2013 .

Arginine vasopressin maintains ethanol tolerance

R. Ritzmann, B. Tabakoff, P. Hoffman, 1978, Nature.

Effects of ethanol on ouabain inhibition of mouse brain (Na+,K+)ATPase activity.

B. Tabakoff, P. Hoffman, B. Salafsky, 1987, Biochemical pharmacology.

Quantitative changes in G proteins do not mediate ethanol-induced downregulation of adenylyl cyclase in mouse cerebral cortex.

J. Whelan, B. Tabakoff, P. Hoffman, 1995, Alcoholism, clinical and experimental research.

Ethanol effects on striatal dopamine receptor-coupled adenylate cyclase and on striatal opiate receptors

B. Tabakoff, P. Hoffman, P. Cordopatis, 1983, Pharmacology Biochemistry and Behavior.

Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.

L. Snell, B. Tabakoff, P. Hoffman, 1996, Brain research. Molecular brain research.

Characteristics of receptors and enzymes in brains of human alcoholics.

B. Tabakoff, P. Hoffman, P. Valverius, 1985, Alcohol.

Tolerance and the etiology of alcoholism: hypothesis and mechanism.

B. Tabakoff, P. Hoffman, 1988, Alcoholism, clinical and experimental research.

β-Adrenergic receptor binding in brain of alcoholics

B. Tabakoff, P. Hoffman, S. Borg, 1989, Experimental Neurology.

Effects of Ethanol, Temperature, and Endogenous Regulatory Factors on the Characteristics of Striatal Opiate Receptors

B. Tabakoff, P. Hoffman, C. Chung, 1984, Journal of neurochemistry.

ALTERATIONS IN RECEPTORS CONTROLLING DOPAMINE SYNTHESIS AFTER CHRONIC ETHANOL INGESTION

B. Tabakoff, P. Hoffman, 1978, Journal of neurochemistry.

ALTERATIONS IN NEUROTRANSMITTER FUNCTION DURING THE DEVELOPMENT OF ETHANOL TOLERANCE AND DEPENDENCE

B. Tabakoff, P. Hoffman, S. Urwyler, 1980, Acta psychiatrica Scandinavica. Supplementum.

MALFUNCTION OF DOPAMINE SYSTEMS IN ETHANOL-DEPENDENT ANIMALS

R. Ritzmann, B. Tabakoff, P. Hoffman, 1979 .

Alterations in dopamine receptor sensitivity by chronic ethanol treatment

B. Tabakoff, P. Hoffman, 1977, Nature.

Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization.

C. Valenzuela, L. Snell, B. Tabakoff, 2000, The Journal of pharmacology and experimental therapeutics.

Commentary on ethanol tolerance.

B. Tabakoff, P. Hoffman, C. Melchior, 1982, Alcoholism, clinical and experimental research.

Conformational constraints within neurohypophyseal hormones influencing the action of chymotrypsin

P. Hoffman, R. Walter, 1974 .

An enzymatically stable peptide with activity in the central nervous system: Its penetration through the blood-CSF barrier

P. Hoffman, R. Walter, M. Bulat, 1977, Brain Research.

Neurohypophyseal hormones, analogs, and fragments: their effect on puromycin-induced amnesia.

L. B. Flexner, J. B. Flexner, P. Hoffman, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Role of catecholamines in the development of tolerance to barbiturates and ethanol.

R. Ritzmann, B. Tabakoff, P. Hoffman, 1977, Advances in experimental medicine and biology.

The 71 kDa glutamate-binding protein is increased in cerebellar granule cells after chronic ethanol treatment.

L. Snell, K. Iorio, B. Tabakoff, 1996, Brain research. Molecular brain research.

Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1.

L. Snell, K. Iorio, B. Tabakoff, 1995, Alcoholism, clinical and experimental research.

Effects of Acetate on Cerebral Blood Flow, Systemic Inflammation, and Behavior in Alcohol Use Disorder.

J. Tanabe, B. Tabakoff, P. Hoffman, 2021, Alcoholism, clinical and experimental research.

Effects of alcohol and acetate on cerebral blood flow: a pilot study.

J. Tanabe, B. Tabakoff, P. Hoffman, 2019, Alcoholism, clinical and experimental research.

NMDA receptors in alcoholism.

P. Hoffman, 2003, International review of neurobiology.

Protein Kinase C Activation Attenuates N‐Methyl‐d‐Aspartate‐Induced Increases in Intracellular Calcium in Cerebellar Granule Cells

L. Snell, B. Tabakoff, P. Hoffman, 1994, Journal of neurochemistry.

Neuroadaptive Functions of the Neuropeptide Arginine Vasopressin.

P. Hoffman, 1994, Annals of the New York Academy of Sciences.

Neurochemical Aspects of Tolerance to and Physical Dependence on Alcohol

B. Tabakoff, P. Hoffman, 1983 .

Measures of physical dependence and involvement of serotonin in withdrawal symptomatology.

B. Tabakoff, P. Hoffman, 1977, Advances in experimental medicine and biology.

Effect of ethanol on mouse cerebral cortical beta-adrenergic receptors.

B. Tabakoff, P. Hoffman, P. Valverius, 1987, Molecular pharmacology.

Using the Phenogen website for ‘in silico’ analysis of morphine‐induced analgesia: identifying candidate genes

Robert W. Williams, B. Tabakoff, P. Hoffman, 2011, Addiction biology.

A systems genetic analysis of alcohol drinking by mice, rats and men: Influence of brain GABAergic transmission

B. Tabakoff, P. Hoffman, K. Kechris, 2011, Neuropharmacology.

Expression Quantitative Trait Loci and The Phenogen Database

B. Tabakoff, P. Hoffman, Sanjiv V. Bhave, 2008, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

P. Hoffman, 2001 .

Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism

B. Tabakoff, P. Hoffman, V. Zídek, 2018, Alcoholism, clinical and experimental research.

Candidate genes and their regulatory elements: alcohol preference and tolerance

N. Grahame, B. Tabakoff, P. Hoffman, 2006, Mammalian Genome.

Development of functional dependence on ethanol in dopaminergic systems.

B. Tabakoff, P. Hoffman, 1979, The Journal of pharmacology and experimental therapeutics.

Antagonism of the behavioral effects of ethanol by naltrexone in BALB/c, C57BL/6, and DBA/2 mice

B. Tabakoff, P. Hoffman, K. Kiianmaa, 2004, Psychopharmacology.

Ethanol’s Action on Brain Biochemistry

B. Tabakoff, P. Hoffman, 1985 .

Ethanol and guanine nucleotide binding proteins: a selective interaction

B. Tabakoff, P. Hoffman, 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mechanism of ethanol inhibition of NMDA receptor function in primary cultures of cerebral cortical cells.

L. Snell, B. Tabakoff, P. Hoffman, 1996, Alcoholism, clinical and experimental research.

Involvement of protein kinase C in ethanol-induced inhibition of NMDA receptor function in cerebellar granule cells.

L. Snell, B. Tabakoff, P. Hoffman, 1994, Alcoholism, clinical and experimental research.

Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference.

J. Wehner, H. Edenberg, B. Tabakoff, 2003, Alcoholism, clinical and experimental research.

Ethanol inhibits the activity of the B form of monoamine oxidase in human platelet and brain tissue

B. Tabakoff, P. Hoffman, John M. Lee, 2004, Psychopharmacology.

Selective effects of ethanol on opiate receptor subtypes in brain

P. Hoffman, S. Khatami, T. Shibuya, 1987, Neuropharmacology.

Ethanol Does Not Modify Opiate‐Mediated Inhibition of Striatal Adenylate Cyclase

B. Tabakoff, P. Hoffman, 1986, Journal of neurochemistry.

Dose-response relationships in attenuation of puromycin-induced amnesia by neurohypophyseal peptides

L. B. Flexner, J. B. Flexner, P. Hoffman, 1977, Brain Research.

The neurobiology of alcohol consumption and alcoholism: An integrative history

B. Tabakoff, P. Hoffman, Boris Tabakoff, 2013, Pharmacology Biochemistry and Behavior.

Differences in platelet enzyme activity between alcoholics and nonalcoholics.

B. Tabakoff, P. Hoffman, John M. Lee, 1988, The New England journal of medicine.

Sex-Specific Role for Adenylyl Cyclase Type 7 in Alcohol Dependence

M. Rietschel, M. Lathrop, D. Zélénika, 2011, Biological Psychiatry.

Prodynorphin and vasopressin mRNA levels are differentially affected by chronic ethanol ingestion in the mouse.

J. Sikela, K. Gulya, P. Hoffman, 1993, Brain research. Molecular brain research.

A long non‐coding RNA (Lrap) modulates brain gene expression and levels of alcohol consumption in rats

S. Janga, G. Homanics, B. Tabakoff, 2020, Genes, brain, and behavior.

Voluntary exposure to a toxin: the genetic influence on ethanol consumption

B. Tabakoff, P. Hoffman, L. Saba, 2018, Mammalian Genome.

Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

Megan K. Mulligan, Megan K Mulligan, Vishwanath R Iyer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

DNA microarray and proteomic strategies for understanding alcohol action.

J. Sikela, J. Pollack, W. Cai, 2006, Alcoholism, clinical and experimental research.

How Adaptation of the Brain to Alcohol Leads to Dependence

P. Hoffman, Sanjiv V. Bhave, P. Clapp, 2008, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

Effects of moderate alcohol consumption on the central nervous system.

M J Eckardt, G F Koob, Ting-kai Li, 1998, Alcoholism: Clinical and Experimental Research.

Ethanol withdrawal seizures produce increased c-fos mRNA in mouse brain.

J. Dave, B. Tabakoff, P. Hoffman, 1990, Molecular pharmacology.

Opiate receptor function after acute and chronic ethanol exposure

B. Tabakoff, P. Hoffman, S. Urwyler, 1980 .

N‐Methyl‐D‐Aspartate Receptors and Ethanol: Inhibition of Calcium Flux and Cyclic GMP Production

B. Tabakoff, P. Hoffman, C. Rabe, 1989, Journal of neurochemistry.

Ethanol and the NMDA receptor.

K. Grant, B. Tabakoff, P. Hoffman, 1990, Alcohol.

Selective inhibition by ethanol of glutamate-stimulated cyclic GMP production in primary cultures of cerebellar granule cells

B. Tabakoff, P. Hoffman, F. Moses, 1989, Neuropharmacology.

Alcohol dependence: a commentary on mechanisms.

B. Tabakoff, P. Hoffman, 1996, Alcohol and alcoholism.

Effects of Chronic Ethanol Treatment on the β‐Adrenergic Receptor‐Coupled Adenylate Cyclase System of Mouse Cerebral Cortex

B. Tabakoff, P. Hoffman, Toshikazu Saito, 1987 .

Effects of chronic ethanol treatment on the beta-adrenergic receptor-coupled adenylate cyclase system of mouse cerebral cortex.

B. Tabakoff, P. Hoffman, T. Saito, 1987, Journal of neurochemistry.

Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel

B. Tabakoff, P. Hoffman, M. Pravenec, 2022, Frontiers in Genetics.

Effects of ethanol on the activity of brain enzymes.

B. Tabakoff, P. Hoffman, S. Liljequist, 1987, Enzyme.

Genetical Genomic Analysis of Complex Phenotypes Using the PhenoGen Website

B. Tabakoff, P. Hoffman, K. Kechris, 2010, Behavior genetics.

The genomic determinants of alcohol preference in mice

N. Grahame, B. Tabakoff, P. Hoffman, 2008, Mammalian Genome.

Selective Breeding, Quantitative Trait Locus Analysis, and Gene Arrays Identify Candidate Genes for Complex Drug-Related Behaviors

B. Tabakoff, P. Hoffman, Sanjiv V. Bhave, 2003, The Journal of Neuroscience.

Influence of sex on genetic regulation of “drinking in the dark” alcohol consumption

B. Tabakoff, P. Hoffman, B. Bennett, 2015, Mammalian Genome.

Platelet adenylyl cyclase activity as a state or trait marker in alcohol dependence: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence.

B. Tabakoff, P. Hoffman, J. Glanz, 2002, Alcoholism, clinical and experimental research.

WHP/ISBRA study on state and trait markers in alcoholism.

J. Whitfield, L. Degenhardt, J. Saunders, 2001, Alcoholism, clinical and experimental research.

Ethanol-Induced Neurodegeneration: Basic Mechanisms and Therapeutic Approaches

P. Hoffman, 2003 .

Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse

Brian E. Vestal, Pamela H. Russell, B. Tabakoff, 2018, BMC Genomics.

Animal Models in Alcohol Re s e a rc h

B. Tabakoff, P. Hoffman, 2000 .

Animal Models in Alcohol Research

B. Tabakoff, P. Hoffman, 2000, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

Genomic Insights into Acute Alcohol Tolerance

B. Tabakoff, P. Hoffman, K. Kechris, 2008, Journal of Pharmacology and Experimental Therapeutics.

Involvement of CNS catecholamines in alcohol self-administration, tolerance and dependence: preclinical studies

P. Hoffman, H. Samson, 1995 .

Neurochemical correlates of ethanol withdrawal: alterations in serotoninergic function

B. Tabakoff, P. Hoffman, F. Moses, 1977, The Journal of pharmacy and pharmacology.

The NMDA receptor antagonist dizocilpine differentially affects environment-dependent and environment-independent ethanol tolerance

B. Tabakoff, P. Hoffman, G. Szabó, 2005, Psychopharmacology.

Recent advances in alcohol research--1990.

B. Tabakoff, P. Hoffman, 1991, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

Chronic ethanol exposure results in increased acute functional tolerance in selected lines of HAFT and LAFT mice

B. Tabakoff, P. Hoffman, G. Szabó, 2001, Psychopharmacology.

The Influence of Neurohypophysial Hormones on Central Nervous System Processes of Adaptation

P. Hoffman, 1993, Annals of the New York Academy of Sciences.

The role of arginine vasopressin in alcohol tolerance.

K. Grant, K. Gulya, J. Dave, 1990, Annals of medicine.

Intraventricular arginine vasopressin maintains ethanol tolerance.

B. Tabakoff, P. Hoffman, C. Melchior, 1984, European journal of pharmacology.

Genetic markers of comorbid depression and alcoholism in women.

B. Tabakoff, P. Hoffman, L. Saba, 2013, Alcoholism, clinical and experimental research.

Peptide--neurotransmitter interactions influencing ethanol tolerance.

B. Tabakoff, P. Hoffman, 1979, Drug and alcohol dependence.

Mechanisms of alcohol tolerance.

B. Tabakoff, P. Hoffman, 1989, Alcohol and alcoholism.

The Biological Basis of Alcohol Tolerance and Intoxication

B. Tabakoff, P. Hoffman, 1985 .

Networking in Biology: The Hybrid Rat Diversity Panel.

B. Tabakoff, P. Hoffman, L. Saba, 2019, Methods in molecular biology.

Transgenic and gene "knockout" models in alcohol research.

T. Yagi, B. Tabakoff, P. Hoffman, 2001, Alcoholism, clinical and experimental research.

Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice.

V. Vasiliou, B. Tabakoff, P. Hoffman, 2006, Alcoholism, clinical and experimental research.

Modification of dopamine receptor-mediated processes after chronic ethanol intoxication: a possible mechanism.

B. Tabakoff, P. Hoffman, 1980, Advances in experimental medicine and biology.

Acute Effects of Ethanol on Pharmacologically Isolated Kainate Receptors in Cerebellar Granule Neurons: Comparison with NMDA and AMPA Receptors

R. Harris, C. Valenzuela, P. Hoffman, 1998, Journal of neurochemistry.

Type 7 adenylyl cyclase-mediated HPA axis responsiveness: Influence of ethanol and sex

B. Tabakoff, P. Hoffman, Laura Saba, 2010 .

Effects of short-chain alcohols and norepinephrine on brain (Na+,K+)ATPase activity.

B. Tabakoff, P. Hoffman, B. Salafsky, 1986, Biochemical pharmacology.

Studies of memory: A reevaluation in mice of the effects of inhibitors on the rate of synthesis of cerebral proteins as related to amnesia

L. B. Flexner, P. Hoffman, T. Rainbow, 1980, Pharmacology Biochemistry and Behavior.

Gangliosides reduce the development of ethanol dependence without affecting ethanol tolerance.

L. Snell, B. Tabakoff, P. Hoffman, 1996, The Journal of pharmacology and experimental therapeutics.

Brain-Derived Neurotrophic Factor Mediates the Anti-Apoptotic Effect of NMDA in Cerebellar Granule Neurons: Signal Transduction Cascades and Site of Ethanol Action

L. Ghoda, P. Hoffman, Sanjiv V. Bhave, 1999, The Journal of Neuroscience.

Ethanol Promotes Apoptosis in Cerebellar Granule Cells by Inhibiting the Trophic Effect of NMDA

P. Hoffman, Sanjiv V. Bhave, 1997, Journal of neurochemistry.

Effects of ethanol on Arrhenius parameters and activity of mouse striatal adenylate cyclase.

B. Tabakoff, P. Hoffman, 1982, Biochemical pharmacology.

Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder

Robert W. Williams, Kerrie H. Lodowski, E. Chesler, 2021, Biological Psychiatry.

Genetic Differences in the N-Methyl- d -Aspartate Receptor

K. Grant, B. Tabakoff, P. Hoffman, 1991 .

Phosphorylation Cascades Control the Actions of Ethanol on Cell cAMP Signalling

B. Tabakoff, P. Hoffman, M. Yoshimura, 2001, Journal of Biomedical Science.

Effect of ethanol on cyclic AMP levels in intact PC12 cells.

B. Tabakoff, P. Hoffman, P. R. Giri, 1990, Biochemical pharmacology.

Phosphorylation Regulates Removal of Synaptic N-Methyl-d-Aspartate Receptors after Withdrawal from Chronic Ethanol Exposure

P. Hoffman, Emily S. Gibson, P. Clapp, 2010, Journal of Pharmacology and Experimental Therapeutics.

A critical appraisal of aldehyde reductase activities in brain

B. Tabakoff, P. Hoffman, 1981 .

Receptor and membrane function in the alcohol tolerant/dependent animal.

J. Fields, B. Tabakoff, P. Hoffman, 1980, Advances in experimental medicine and biology.

World Health Organization/International Society for Biomedical Research on Alcoholism study on state and trait markers of alcohol use and dependence: back to the future.

J. Whitfield, F. Wurst, H. Ko, 2005, Alcoholism, clinical and experimental research.

Phosphorylation cascades control the actions of ethanol on cell cAMP signalling.

B. Tabakoff, P. Hoffman, M. Yoshimura, 2001, Journal of biomedical science.

Ethanol enhancement of isoproterenol-stimulated melatonin and cyclic AMP release from cultured pineal glands.

B. Tabakoff, P. Hoffman, L. Tamarkin, 1989, The Journal of pharmacology and experimental therapeutics.

Opposite changes in turnover of noradrenaline and dopamine in the CNS of ethanol-dependent mice

P. Hoffman, G. Eisenhofer, G. Szabó, 1990, Neuropharmacology.

Ethanol, sedative hypnotics, and glutamate receptor function in brain and cultured cells

B. Tabakoff, P. Hoffman, 1993, Behavior genetics.

Brain forskolin binding in mice dependent on and tolerant to ethanol

B. Tabakoff, P. Hoffman, P. Valverius, 1989, Brain Research.

Radioligand binding to the N-methyl-d-aspartate receptor/ionophore complex: alterations by ethanol in vitro and by chronic in vivo ethanol ingestion

L. Snell, B. Tabakoff, P. Hoffman, 1993, Brain Research.

Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal

K. Grant, K. Gulya, B. Tabakoff, 1991, Brain Research.

Dopamine receptor function after chronic ingestion of ethanol.

R. Ritzmann, B. Tabakoff, P. Hoffman, 1978, Life sciences.

Pentobarbital Decreases the g-Aminobutyric AcidA Receptor Subunit gamma-2 Long / Short mRNA Ratio by a Mechanism Distinct from Receptor Occupation 1

R. Tyndale, R. Olsen, B. Tabakoff, 1997 .

Factors in ethanol tolerance.

B. Tabakoff, P. Hoffman, C. Melchior, 1984, Science.

Distribution, survival and biological effects in mice of a behaviorally active, enzymatically stable peptide: Pharmacokinetics of cyclo(Leu-Gly) and puromycin-induced amnesia

L. B. Flexner, J. B. Flexner, P. Hoffman, 1979, Pharmacology Biochemistry and Behavior.

Ethanol Alters Kinetic Characteristics and Function of Striatal Morphine Receptors

B. Tabakoff, P. Hoffman, S. Urwyler, 1981, Journal of neurochemistry.

The influence of arginine vasopressin and oxytocin on ethanol dependence and tolerance.

R. Ritzmann, P. Hoffman, B. Tabokoff, 1979, Currents in alcoholism.

INFLUENCES OF NEUROHYPOPHYSEAL HORMONES AND RELATED PEPTIDES ON ADAPTIVE PHENOMENA IN THE CENTRAL NERVOUS SYSTEM

L. B. Flexner, J. B. Flexner, R. Ritzmann, 1982 .

Neurohypophyseal peptide influences on ethanol tolerance and acute effects of ethanol

R. Ritzmann, B. Tabakoff, P. Hoffman, 1980, Pharmacology Biochemistry and Behavior.

Differential effects of ethanol on the striatal and cortical adenylate cyclase system.

B. Tabakoff, P. Hoffman, G. Luthin, 1987, Japanese journal of pharmacology.

The Changing View of Ethanol’s Actions: From Generalities to Specifics

B. Tabakoff, P. Hoffman, 1991 .

Works Title Genetical genomic determinants of alcohol consumption in rats and humans

G. Koob, J. Whitfield, B. Grant, 2009 .

Neurohypophyseal peptides maintain tolerance to the incoordinating effects of ethanol

B. Tabakoff, P. Hoffman, 1984, Pharmacology Biochemistry and Behavior.

Decreased performance in a delayed alternation task by rats genetically deficient in vasopressin

K. Grant, P. Hoffman, G. Colombo, 1992, Physiology & Behavior.

Receptor-gated ion channels may be selective CNS targets for ethanol.

P. Hoffman, R. Gonzales, 1991, Trends in pharmacological sciences.

Overexpression of type 7 adenylyl cyclase in the mouse brain enhances acute and chronic actions of morphine.

B. Tabakoff, P. Hoffman, M. Yoshimura, 2000, Molecular pharmacology.

Adenylyl Cyclases: mRNA and Characteristics of Enzyme Activity in Three Areas of Brain

B. Tabakoff, P. Hoffman, K. Hellevuo, 1996, Journal of neurochemistry.

NMDA receptors in mice bred to be prone or resistant to ethanol withdrawal seizures.

J. Crabbe, B. Tabakoff, P. Hoffman, 1990, European journal of pharmacology.

Structural requirements for neurohypophyseal peptide maintenance of ethanol tolerance

P. Hoffman, 1982, Pharmacology Biochemistry and Behavior.

Chronic ethanol ingestion decreases vasopressin mRNA in hypothalamic and extrahypothalamic nuclei of mouse brain

K. Gulya, J. Dave, P. Hoffman, 1991, Brain Research.

Comparative effects of arginine vasopressin, [pGlu4,Cyt6]arginine vasopressin-(4-9) and nerve growth factor on maintenance of functional tolerance to ethanol in mice.

B. Tabakoff, P. Hoffman, G. Szabó, 1991, European journal of pharmacology.

The effects of vasopressin and related peptides on tolerance to ethanol

B. Tabakoff, P. Hoffman, G. Szabó, 1988 .

Centrally acting peptides and tolerance to ethanol.

B. Tabakoff, P. Hoffman, 1981, Currents in alcoholism.

Selectivity of ethanol's actions on brain receptor systems: Catecholamines and ethanol

B. Tabakoff, P. Hoffman, P. Valverius, 1988 .

Using Baseline Transcriptional Connectomes in Rat to Identify Genetic Pathways Associated with Predisposition to Complex Traits.

B. Tabakoff, P. Hoffman, L. Saba, 2017, Methods in molecular biology.

Selective Effects of Sedative/Hypnotic Drugs on Excitatory Amino Acid Receptors in Brain a

B. Tabakoff, P. Hoffman, C. Rabe, 1991, Annals of the New York Academy of Sciences.

The role of the NMDA receptor in ethanol withdrawal.

B. Tabakoff, P. Hoffman, Boris Tabakoff, 1994, EXS.

Effect of ethanol on DARPP-32 phosphorylation in transgenic mice that express human type VII adenylyl cyclase in brain.

B. Tabakoff, P. Hoffman, T. Donohue, 2005, Alcoholism, clinical and experimental research.

Immunological assessment of the distribution of Type VII adenylyl cyclase in brain

N. Mons, B. Tabakoff, P. Hoffman, 1998, Brain Research.

A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.

D. Cooper, B. Tabakoff, P. Hoffman, 1993, Biochemical and biophysical research communications.

Chronic ethanol exposure delays the ‘developmental switch’ of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons

L. Snell, B. Tabakoff, P. Hoffman, 2001, Journal of neurochemistry.

Chronic Ethanol Exposure Attenuates the Anti‐Apoptotic Effect of NMDA in Cerebellar Granule Neurons

L. Snell, B. Tabakoff, P. Hoffman, 2000, Journal of neurochemistry.

Uncovering the liver’s role in immunity through RNA co-expression networks

B. Tabakoff, P. Hoffman, M. Pravenec, 2016, Mammalian Genome.

Bromacetyl-oxytocin, an irreversible inhibitor of neurohypophyseal hormone-stimulated adenylate cyclase, and a possible affinity label for hormone receptors.

P. Hoffman, T. Dousa, R. Walter, 1972, Endocrinology.

A Sex-Specific Role of Type VII Adenylyl Cyclase in Depression

B. Grant, L. Snell, B. Tabakoff, 2006, The Journal of Neuroscience.

A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain.

D. Lovinger, A. M. Rush, L. Snell, 2016, European journal of pharmacology.

Ethanol sensitivity of NMDA receptor function in developing cerebellar granule neurons.

L. Snell, B. Tabakoff, P. Hoffman, 1999, European journal of pharmacology.

Chronic ethanol exposure uncouples vasopressin synthesis and secretion in rats

J. Dave, P. Hoffman, 1991, Neuropharmacology.

The Effects of Ethanol on Neuronal and Glial Differentiation and Development

M. Tateno, B. Tabakoff, P. Hoffman, 2005 .

To be or not to be: how ethanol can affect neuronal death during development.

B. Tabakoff, P. Hoffman, 1996, Alcoholism, clinical and experimental research.

Effects of moderate alcohol consumption on the central nervous system.

Ting-kai Li, G. Koob, K. Grant, 1998, Alcoholism, clinical and experimental research.

Effect of ethanol on cardiac β-adrenoceptors

B. Tabakoff, P. Hoffman, M. Kwast, 1987 .

Monoamine oxidases and alcoholism: studies in unrelated alcoholics, normal controls and alcoholic families.

C. Robert Cloninger, B. Suarez, B. Tabakoff, 1994, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

Uncovering the liver’s role in immunity through RNA co-expression networks

Michal Pravenec, Laura M. Saba, B. Tabakoff, 2016, Mammalian Genome.

Regulation of vasopressin and oxytocin synthesis in anterior pituitary and peripheral tissues.

J. Dave, B. Tabakoff, P. Hoffman, 1988, Advances in Alcohol & Substance Abuse.

Comparison of some biological activities of arginine vasotocin and synthetic analogs

P. Hoffman, R. Walter, Dasha Surovec, 1974, Experientia.

Intraventricular arginine vasopressin blocks the acquisition of ethanol tolerance in mice.

P. Hoffman, C. Melchior, S. A. Mannix, 1986, European Journal of Pharmacology.

The Neurochemistry of Ethanol Tolerance

B. Tabakoff, P. Hoffman, 1991 .

Glutamate receptors in alcohol withdrawal-induced neurotoxicity

P. Hoffman, 1995, Metabolic Brain Disease.

Vasopressin maintenance of ethanol tolerance requires intact brain noradrenergic systems.

B. Tabakoff, P. Hoffman, C. Melchior, 1983, Life sciences.

Glutamate-induced neurotoxicity is increased in cerebellar granule cells exposed chronically to ethanol.

K. Iorio, B. Tabakoff, P. Hoffman, 1993, European journal of pharmacology.

18F-labeled benzamides for studying the dopamine D2 receptor with positron emission tomography.

R. Mach, P. Hoffman, R. Luedtke, 1993, Journal of medicinal chemistry.

How Adaptation of the Brain to Alcohol Leads to Dependence

P. Hoffman, Sanjiv V. Bhave, P. Clapp, 2008, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

Influence of sex on genetic regulation of “drinking in the dark” alcohol consumption

B. Tabakoff, P. Hoffman, B. Bennett, 2015, Mammalian Genome.

Antisense oligonucleotide to c-fos blocks the ability of arginine vasopressin to maintain ethanol tolerance.

P. Hoffman, G. Szabó, K. Nunley, 1996, European Journal of Pharmacology.

Proposed mechanisms of action of neurohypophyseal peptides in memory processes and possible routes for the biosynthesis of peptides with a C-terminal carboxamide group.

P. Hoffman, R. Walter, 1977, Advances in biochemical psychopharmacology.

Alterations in opiate receptor function after chronic ethanol exposure.

B. Tabakoff, P. Hoffman, S. Urwyler, 1982, The Journal of pharmacology and experimental therapeutics.

Type 7 Adenylyl Cyclase-Mediated Hypothalamic-Pituitary-Adrenal Axis Responsiveness: Influence of Ethanol and Sex

B. Tabakoff, P. Hoffman, L. Saba, 2010, Journal of Pharmacology and Experimental Therapeutics.

The biometric measurement of alcohol consumption.

M. Schwandt, L. Snell, D. Herion, 2012, Alcoholism, clinical and experimental research.