H. Konishi

I. Hanamura, S. Tsuzuki, H. Konishi, 2020, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

The timing and location of protein activation and inactivation during cell division

S. Tsuzuki, H. Konishi, Y. Hosokawa, 2022 .

The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation

A. Weeraratna, P. Argani, A. D. De Marzo, 2012, Breast Cancer Research.

BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemia

S. Tsuzuki, H. Konishi, Y. Hosokawa, 2022, Haematologica.

Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages

H. Konishi, Y. Hosokawa, Akinobu Ota, 2015, Molecular and Cellular Biochemistry.

Arsenic trioxide prevents nitric oxide production in lipopolysaccharide ‐stimulated RAW 264.7 by inhibiting a TRIF‐dependent pathway

H. Konishi, T. Yokochi, Y. Hosokawa, 2013, Cancer science.

CD52 is a novel target for the treatment of FLT3-ITD-mutated myeloid leukemia

I. Hanamura, S. Tsuzuki, R. Ueda, 2021, Cell death discovery.

Characterization of HACD1 K64Q mutant found in arrhythmogenic right ventricular dysplasia patients.

H. Konishi, A. Kihara, Y. Ohno, 2010, Journal of biochemistry.

Assessment of the long-term transcriptional activity of a 550-bp-long human β-actin promoter region.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2012, Plasmid.

Controversial BRCA1 allelotypes in commonly used breast cancer cell lines

B. Park, H. Konishi, Y. Hosokawa, 2009, Breast Cancer Research and Treatment.

The PIK3CA gene is mutated with high frequency in human breast cancers

Hiroyuki Konishi, Brock A. Peters, Victor E. Velculescu, 2004, Cancer biology & therapy.

Altered regulation of c-jun and its involvement in anchorage-independent growth of human lung cancers

R. Ueda, H. Konishi, K. Yanagisawa, 2006, Oncogene.

PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells

B. Park, H. Konishi, M. Mohseni, 2011, Cancer biology & therapy.

Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers

S. Nomoto, T. Mitsudomi, H. Konishi, 2000, Genes, chromosomes & cancer.

Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.

B. Park, K. Bachman, H. Konishi, 2007, Cancer research.

Topographical distributions of allelic loss in individual non-small-cell lung cancers.

Y. Yatabe, T. Mitsudomi, H. Konishi, 2000, The American journal of pathology.

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at distal 17p13.3 in human lung cancer

Y. Yatabe, H. Konishi, H. Osada, 2003, Oncogene.

Histological type-selective, tumor-predominant expression of a novel CHK1 isoform and infrequent in vivo somatic CHK2 mutation in small cell lung cancer.

H. Konishi, H. Osada, T. Harano, 2000, Cancer research.

Advances in Brief Search for Mutations and Examination of Allei ic Expression Imbalance of the p 73 Gene at Ip 36 . 33 in Human Lung Cancers 1

S. Nomoto, H. Konishi, Takashi Takahashi, 2006 .

Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers.

S. Nomoto, H. Konishi, M. Kondo, 1998, Cancer research.

The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.

R. Arceci, B. Park, H. Konishi, 2008, Blood.

Novel metastasis-related gene CIM functions in the regulation of multiple cellular stress-response pathways.

Y. Yatabe, T. Mitsudomi, S. Tomida, 2010, Cancer research.

ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.

H. Konishi, M. Moriguchi, Y. Naito, 2017, Cancer letters.

Persistent increase in chromosome instability in lung cancer: possible indirect involvement of p53 inactivation.

T. Mitsudomi, H. Konishi, H. Osada, 2001, The American journal of pathology.

Experimental strategies to achieve efficient targeted knock-in via tandem paired nicking

S. Tsuzuki, H. Konishi, Y. Hosokawa, 2021, Scientific Reports.

Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo

Akira Masuda, Hiroyuki Konishi, Akimasa Nakao, 2002, Oncogene.

Inhibition of NADPH oxidase 2 induces apoptosis in osteosarcoma: The role of reactive oxygen species in cell proliferation.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2018, Oncology letters.

Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells

H. Konishi, Y. Hosokawa, Akinobu Ota, 2014, Cellular Oncology.

Advances in Brief Histological Type-selective , Tumor-predominant Expression of a Novel CHK 1 Isoform and Infrequent in Vivo Somatic CHK 2 Mutation in Small Cell Lung Cancer 1

H. Konishi, H. Osada, T. Harano, 2000 .

Lipopolysaccharide augments the uptake of oxidized LDL by up-regulating lectin-like oxidized LDL receptor-1 in macrophages

H. Konishi, Y. Hosokawa, Akinobu Ota, 2015, Molecular and Cellular Biochemistry.

Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53.

A. Toyoda, S. Tsuzuki, H. Konishi, 2020, Cell reports.

Tandem paired nicking promotes precise genome editing with scarce interference by p53

A. Toyoda, S. Tsuzuki, H. Konishi, 2019, bioRxiv.

High-resolution 400K oligonucleotide array comparative genomic hybridization analysis of neurofibromatosis type 1-associated cutaneous neurofibromas.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2015, Gene.

Tamoxifen-stimulated growth of breast cancer due to p21 loss

P. Argani, A. D. De Marzo, B. Park, 2008, Proceedings of the National Academy of Sciences.

Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2013, Toxicology and applied pharmacology.

The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation

A. Weeraratna, P. Argani, A. D. De Marzo, 2012, Breast Cancer Research.

Plumbagin suppresses tumor cell growth in oral squamous cell carcinoma cell lines.

H. Konishi, Akinobu Ota, S. Karnan, 2015, Oral diseases.

Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesothelioma

I. Hanamura, S. Tsuzuki, H. Konishi, 2020, Cell death discovery.

Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.

P. Argani, B. Park, H. Konishi, 2013, Cancer research.

Molecular and Cellular Pathobiology Single Copies of Mutant KRAS and Mutant PIK 3 CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

P. Argani, B. Park, H. Konishi, 2013 .

Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells

I. Hanamura, S. Tsuzuki, H. Konishi, 2020, Cancer science.

Arsenic upregulates the expression of angiotensin II Type I receptor in mouse aortic endothelial cells.

H. Konishi, Y. Hosokawa, S. Karnan, 2013, Toxicology letters.

Establishment and characterization of CRISPR/Cas9‐mediated NF2 −/− human mesothelial cell line: Molecular insight into fibroblast growth factor receptor 2 in malignant pleural mesothelioma

I. Hanamura, S. Tsuzuki, H. Konishi, 2018, Cancer science.

Inhibition of Nox1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2016, Oncology reports.

Inhibition of Nox 1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines

H. Konishi, Y. Hosokawa, M. Wahiduzzaman, 2016 .

Δ40p53α suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells

H. Konishi, Y. Hosokawa, Akinobu Ota, 2017, Journal of Cell Science.

Delta 40 p 53 suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells

H. Konishi, Y. Hosokawa, Akinobu Ota, 2016 .

Improved methods of AAV-mediated gene targeting for human cell lines using ribosome-skipping 2A peptide

H. Konishi, Y. Hosokawa, Akinobu Ota, 2015, Nucleic acids research.

Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations

B. Vogelstein, K. Polyak, D. Gorkin, 2010, Oncogene.

Erratum: The PIK3CA gene is mutated with high frequency in human breast cancers (Cancer Biology and Therapy (2004) 3 (772-775))

B. Peters, M. Ellis, J. Ptak, 2005 .

p21 gene knock down does not identify genetic effectors seen with gene knock out

A. Weeraratna, B. Park, K. Bachman, 2007, Cancer biology & therapy.

Interleukin-1 alpha mediates the growth proliferative effects of transforming growth factor-beta in p21 null MCF-10A human mammary epithelial cells

A. Weeraratna, W. Wood, K. Becker, 2006, Oncogene.

CAMK2D: a novel molecular target for BAP1-deficient malignant mesothelioma

I. Hanamura, S. Tsuzuki, H. Konishi, 2023, Cell death discovery.

Inhibition of NADPH oxidase 4 induces apoptosis in malignant mesothelioma: Role of reactive oxygen species.

H. Konishi, Y. Hosokawa, Akinobu Ota, 2015, Oncology Report.

Arsenic trioxide prevents nitric oxide production in lipopolysaccharide ‐stimulated RAW 264.7 by inhibiting a TRIF‐dependent pathway

H. Konishi, T. Yokochi, Y. Hosokawa, 2013, Cancer science.

ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells

I. Hanamura, H. Konishi, Y. Hosokawa, 2024, Cell death discovery.

Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma

I. Hanamura, H. Konishi, Y. Hosokawa, 2024, bioRxiv.