K. Akagawa

发表

Differential involvement of synaptic vesicle and presynaptic plasma membrane proteins in Alzheimer's disease.

T. Taniguchi, S. Shimohama, S. Kamiya, 1997, Biochemical and biophysical research communications.

Molecular Cloning of Guinea Pig Angiotensin Type 1 Receptor

K. Akagawa, A. Kuwahara, Y. Hosoda, 2000, Neurosignals.

Calcium loading capacity and morphological changes in mitochondria in an ischemic preconditioned model

K. Akagawa, T. Mishima, H. Kawakami, 2008, Neuroscience Letters.

Identification of individual barley chromosomes based on repetitive sequences: conservative distribution of Afa-family repetitive sequences on the chromosomes of barley and wheat.

M. Yamamoto, K. Akagawa, H. Tsujimoto, 1997, Genes & genetic systems.

Syntaxin 1 (HPC-1) Is Associated with Chromaffin Granules (*)

K. Akagawa, M. Tagaya, Y. Moriyama, 1995, The Journal of Biological Chemistry.

Enzyme-treated Asparagus officinalis Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescence-accelerated Mice

T. Kizaki, K. Akagawa, T. Sakurai, 2014, Natural product communications.

Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of βAPP in neuronal cells

K. Akagawa, H. Mori, T. Tomiyama, 2005, Journal of neurochemistry.

RNA interference‐mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles

K. Akagawa, Kei Suga, Ayako Saito, 2005, FEBS letters.

Presence of light-responding neurons in the reaggregate cultures of rat retinae.

K. Akagawa, 1990, Brain research. Developmental brain research.

The cell‐ and tissue‐specific transcription mechanism of the TATA‐less syntaxin 1A gene

K. Mikoshiba, K. Akagawa, T. Nakayama, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production.

K. Akagawa, H. Mori, T. Tomiyama, 2004, The Biochemical journal.

Characterization of HPC-1 antigen, an isoform of syntaxin-1, with the isoform-specific monoclonal antibody, 14D8

K. Akagawa, Y. Kushima, T. Fujiwara, 1997, Journal of Molecular Neuroscience.

Mapping of the human HPC-1/syntaxin 1A gene (STX1A) to chromosome 7 band q11.2.

K. Mikoshiba, S. Asakawa, K. Akagawa, 1997, Genomics.

Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy

K. Akagawa, H. Watada, T. Okamura, 2013, Proceedings of the National Academy of Sciences.

Syntaxin 1B, but Not Syntaxin 1A, Is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses

K. Akagawa, M. Kanai-Azuma, T. Mishima, 2014, PloS one.

Reduction of neurotransmitter release by the exogenous H3 domain peptide of HPC-1/syntaxin 1A in cultured rat hippocampal neurons

K. Akagawa, T. Mishima, T. Fujiwara, 2002, Neuroscience Letters.

Expression and functional role of syntaxin 1/HPC-1 in pancreatic beta cells. Syntaxin 1A, but not 1B, plays a negative role in regulatory insulin release pathway.

K. Akagawa, S. Nagamatsu, H. Sawa, 1996, The Journal of biological chemistry.

Loss of Granuphilin and Loss of Syntaxin-1A Cause Differential Effects on Insulin Granule Docking and Fusion*

Hao Wang, K. Akagawa, T. Izumi, 2011, The Journal of Biological Chemistry.

Expression of the exocytotic protein syntaxin in mouse oocytes.

K. Akagawa, S. Komatsu, H. Tanaka, 2003, Reproduction.

The role of Sp3 transcription factor in syntaxin 1A gene silencing

K. Akagawa, T. Nakayama, Yasuo Terao, 2022, Gene Reports.

Transcription regulation mechanism of the syntaxin 1A gene via protein kinase A.

K. Akagawa, T. Nakayama, 2017, The Biochemical journal.

ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion.

K. Akagawa, Kei Suga, Ayako Saito, 2015, Experimental cell research.

Syntaxin 1C, a soluble form of syntaxin, attenuates membrane recycling by destabilizing microtubules

K. Akagawa, H. Kamiguchi, T. Nakayama, 2012, Journal of Cell Science.

Activation of Syntaxin 1C, an Alternative Splice Variant of HPC-1/Syntaxin 1A, by Phorbol 12-Myristate 13-Acetate (PMA) Suppresses Glucose Transport into Astroglioma Cells via the Glucose Transporter-1 (GLUT-1)*

K. Mikoshiba, T. Yamamori, K. Akagawa, 2004, Journal of Biological Chemistry.

Exocytosis relating proteins in the nervous system

K. Akagawa, K. Yamaguchi, 1994, Neuroscience Research.

Localization of HPC-1/syntaxin 1 in developing rat cerebellar cortex.

K. Akagawa, Y. Tashiro, F. Miya, 1996, Cell structure and function.

Overexpressed syntaxin 1A/HPC-1 inhibits insulin secretion via a regulated pathway, but does not influence glucose metabolism and intracellular Ca2+ in insulinoma cell line beta TC3 cells.

K. Akagawa, K. Yamaguchi, S. Nagamatsu, 1997, Biochemical and biophysical research communications.

Syntaxin 1B regulates synaptic GABA release and extracellular GABA concentration, and is associated with temperature‐dependent seizures

K. Akagawa, Y. Terao, T. Mishima, 2020, Journal of neurochemistry.

Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex.

K. Akagawa, E. Kominami, S. Kohsaka, 2003, Biochemical and biophysical research communications.

Golgi stress induces upregulation of the ER-Golgi SNARE Syntaxin-5, altered βAPP processing, and Caspase-3-dependent apoptosis in NG108-15 cells

K. Akagawa, M. Ushimaru, Kei Suga, 2022, Molecular and Cellular Neuroscience.

Important Roles of the C-Terminal Portion of HPC-1/Syntaxin 1A in Membrane Anchoring and Intracellular Localization1

K. Akagawa, R. Masaki, Y. Tashiro, 1998, Journal of biochemistry.

Expression of syntaxin 1C, an alternative splice variant of HPC‐1/syntaxin 1A, is enhanced by phorbol‐ester stimulation in astroglioma: participation of the PKC signaling pathway 1

K. Mikoshiba, T. Yamamori, K. Akagawa, 2003, FEBS letters.

Syntaxin 8 has two functionally distinct di-leucine-based motifs

K. Akagawa, T. Izumi, K. Kasai, 2007, Cellular & Molecular Biology Letters.

Roles of the cytoplasmic and transmembrane domains of syntaxins in intracellular localization and trafficking.

K. Akagawa, K. Kasai, 2001, Journal of cell science.

Interaction of HPC-1/syntaxin 1A with the cytoskeletal protein, tubulin.

T. Yamamori, K. Akagawa, K. Yamaguchi, 1997, Biochemical and biophysical research communications.

A MONOCLONAL ANTIBODY 2.6A RECOGNIZES A MINOR COMPONENT PROTEIN OF 38 K IN THE PLAIN SYNAPTIC VESICLES

C. Barnstable, K. Akagawa, K. Uyemura, 1988 .

Mitochondrial hyperpolarization after transient oxygen-glucose deprivation and subsequent apoptosis in cultured rat hippocampal neurons

K. Akagawa, T. Mishima, Y. Iwao, 2003, Brain Research.

Mitochondrial membrane potential and intracellular ATP content after transient experimental ischemia in the cultured hippocampal neuron

K. Akagawa, T. Mishima, Y. Iwao, 2003, Neurochemistry International.

Neuroprotective effect of propofol on necrosis and apoptosis following oxygen–glucose deprivation—Relationship between mitochondrial membrane potential and mode of death

K. Akagawa, T. Mishima, Y. Iwao, 2006, Brain Research.

Inhibitory effect of peripheral myelin P2 protein on the proliferation of a tumor cell line

K. Akagawa, K. Uyemura, 1989 .

HPC-1/syntaxin 1A suppresses exocytosis of PC12 cells.

T. Watanabe, K. Akagawa, K. Yamaguchi, 1999, Journal of biochemistry.

Neuron specific expression of a membrane protein, HPC-1: tissue distribution, and cellular and subcellular localization of immunoreactivity and mRNA.

K. Akagawa, A. Inoue, Akihiro Inoue, 1993, Brain research. Molecular brain research.

Partial Purification and Properties of the Inhibitors of Na,K‐ATPase and Ouabain‐Binding in Bovine Central Nervous System

K. Akagawa, Y. Tsukada, Y. Tsukada, 1984, Journal of neurochemistry.

Immunohistochemical demonstration of neuron specific antigen, HPC-1 in the enteric nervous system of the guinea-pig distal colon

K. Akagawa, A. Kuwahara, Y. Tsutsui, 1993, Neuroscience Letters.

Altered immunoreactivity of HPC-1/syntaxin 1A in proliferated nerve fibers in the human aganglionic colon of hirschsprung’s disease

Yasuo Ito, K. Akagawa, T. Fujiwara, 2001, Journal of Molecular Neuroscience.

Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents.

J. Mcghee, K. Akagawa, W. Zhou, 2000, The Journal of clinical investigation.

Inhibition of microtubule assembly by HPC-1/syntaxin 1A, an exocytosis relating protein.

K. Akagawa, H. Hotani, T. Shibuya, 1999, Cell structure and function.

Histiotypic organization and cell differentiation in rat retinal reaggregate cultures

C. Barnstable, K. Akagawa, D. Hicks, 1987, Brain Research.

Identification and characterization of cell types in monolayer cultures of rat retina using monoclonal antibodies

C. Barnstable, K. Akagawa, 1986, Brain Research.

Immunoelectron microscopic localization of the HPC-1 antigen in rat cerebellum

K. Akagawa, Y. Tashiro, A. Inoue, 1993, Journal of neurocytology.

HPC‐1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5‐HTergic systems

K. Akagawa, T. Yoshikawa, T. Fujiwara, 2010, The European journal of neuroscience.

Calcium- and voltage-dependent potassium channel in the rat retinal amacrine cells identified in vitro using a cell type-specific monoclonal antibody

K. Akagawa, H. Hayashi, M. Takada, 1990, Brain Research.

Expression and Functional Role of Syntaxin 1/HPC-1 in Pancreatic β Cells

K. Akagawa, S. Nagamatsu, H. Sawa, 1996, The Journal of Biological Chemistry.

Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion

K. Akagawa, Kei Suga, Ayako Saito, 2015, Data in brief.

HPC-1/syntaxin-1A activity in the enteric nervous system of developing rat gastrointestinal tract.

K. Akagawa, Y. Ito, N. Seki, 1997, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

Regulation of Exocytosis through Ca2+/ATP-Dependent Binding of Autophosphorylated Ca2+/Calmodulin-Activated Protein Kinase II to Syntaxin 1A

K. Kumakura, K. Akagawa, H. Taniguchi, 2002, The Journal of Neuroscience.

Transient decrease of HPC-1/syntaxin-1A mRNA in the rat hippocampus by kainic acid

K. Akagawa, I. Fujino, T. Fujiwara, 1997, Neuroscience Research.

Enhancement of synaptic transmission and nociceptive behaviour in HPC‐1/syntaxin 1A knockout mice following peripheral nerve injury

K. Akagawa, T. Takasusuki, S. Yamaguchi, 2007, The European journal of neuroscience.

Presence and characteristics of catecholamine‐sensitive Na‐K ATPase in rat striatum

K. Akagawa, Y. Tsukada, 1979, Journal of neurochemistry.

High potassium promotes differentiation of retinal neurons but does not favor rod differentiation.

H. Kimura, K. Akagawa, M. Araki, 1995, Brain research. Developmental brain research.

Unusual social behavior in HPC‐1/syntaxin1A knockout mice is caused by disruption of the oxytocinergic neural system

K. Akagawa, T. Fujiwara, T. Kofuji, 2016, Journal of neurochemistry.

HPC‐1/syntaxin 1A and syntaxin 1B play distinct roles in neuronal survival

K. Akagawa, T. Mishima, T. Fujiwara, 2014, Journal of neurochemistry.

Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis

Mica Ohara-Imaizumi, Shinya Nagamatsu, Yoko Nakamichi, 2007, The Journal of cell biology.

Analysis of Knock-Out Mice to Determine the Role of HPC-1/Syntaxin 1A in Expressing Synaptic Plasticity

Keiji Tanaka, K. Akagawa, T. Chiba, 2006, The Journal of Neuroscience.

A monoclonal antibody 5E5 recognizes an intranuclear antigen selectively present in a subpopulation of the neurons

K. Akagawa, K. Yoshimura, K. Uyemura, 1990, Brain Research.

Differential expression of neuroD in primary cultures of cerebral cortical neurons.

K. Akagawa, I. Mizuta, K. Uyemura, 1997, Experimental cell research.

Hemizygous deletion of the HPC-1/syntaxin 1A gene (STX1A) in patients with Williams syndrome

K. Mikoshiba, K. Akagawa, Y. Shimizu, 1998, Cytogenetic and Genome Research.

Enhancement of neurite-sprouting by suppression of HPC-1/syntaxin 1A activity in cultured vertebrate nerve cells

K. Akagawa, K. Yamaguchi, T. Nakayama, 1996, Brain Research.

Dysfunction of the Hypothalamic‐Pituitary‐Adrenal axis in STX1A Knockout Mice

K. Akagawa, T. Fujiwara, T. Kofuji, 2011, Journal of neuroendocrinology.

Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training.

T. Kizaki, K. Akagawa, T. Sakurai, 2011, Biochemical and biophysical research communications.

A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice

K. Akagawa, M. Tamaru, T. Fujiwara, 2017, Neuroscience Letters.

The Syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of {beta}-amyloid precursor protein.

K. Akagawa, H. Mori, T. Tomiyama, 2009, Journal of biochemistry.

Syntaxin 1A Gene Is Negatively Regulated in a Cell/Tissue Specific Manner by YY1 Transcription Factor, Which Binds to the −183 to −137 Promoter Region Together with Gene Silencing Factors Including Histone Deacetylase

K. Akagawa, Y. Terao, Toshiyuki Fukutomi, 2021, Biomolecules.

Unusual retinal layer organization in HPC-1/syntaxin 1A knockout mice

K. Akagawa, Y. Kaneko, R. Suge, 2011, Journal of Molecular Histology.

Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.

K. Akagawa, A. Inoue, K. Obata, 1992, The Journal of biological chemistry.

A marker of early amacrine cell development in rat retina.

C. Barnstable, K. Akagawa, R. Hofstein, 1985, Brain research.

Differential expression of rat brain synaptic proteins in development and aging.

T. Shirao, T. Taniguchi, S. Shimohama, 1998, Biochemical and biophysical research communications.

Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region

Kazuto Kobayashi, N. Kai, K. Akagawa, 2008, Journal of Neuroscience Methods.

Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells

T. Kizaki, K. Akagawa, H. Nishioka, 2013, British Journal of Nutrition.

Developing rat pineal cells manifest potential of neuronal differentiation in vitro

H. Kimura, K. Akagawa, T. Mashiko, 1994, Neuroscience Research.

Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: Further characterization of presynaptic mechanisms

K. Akagawa, S. Yamaguchi, T. Fujiwara, 2014, Neuroscience Letters.

Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus

T. Kizaki, K. Akagawa, T. Sakurai, 2012 .

Suppression of transmitter release by Tat HPC-1/syntaxin 1A fusion protein.

T. Yamamori, K. Akagawa, T. Fujiwara, 2001, Biochimica et biophysica acta.

Disturbance of the reciprocal-interaction between the OXTergic and DAergic systems in the CNS causes atypical social behavior in syntaxin 1A knockout mice

K. Akagawa, T. Fujiwara, T. Kofuji, 2021, Behavioural Brain Research.

Neurochemical Studies on the Cerebellar Hypoplasia of Gunn Rat (Hereditary Hyperbilirubinemic Rat)

K. Mikoshiba, K. Akagawa, Y. Tsukada, 1982, Journal of neurochemistry.

Increase in number of functional release sites by cyclic AMP-dependent protein kinase in cultured neurons isolated from hippocampal dentate gyrus

A. Ogura, K. Akagawa, K. Yamaguchi, 2001, Neuroscience Research.

Optical recording of spontaneous respiratory neuron activity in the rat brain stem.

K. Akagawa, H. Onimaru, Y. Nakazono, 2001, The Japanese journal of physiology.

Syntaxin 1B contributes to regulation of the dopaminergic system through GABA transmission in the CNS

K. Akagawa, T. Mishima, T. Fujiwara, 2017, The European journal of neuroscience.

Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice

K. Akagawa, T. Mishima, T. Fujiwara, 2012, The Journal of Neuroscience.

Activity of Erythrocyte Na,K‐ATPase in Manic Patients

K. Akagawa, Y. Tsukada, Kimio Akagawa, 1980, Journal of neurochemistry.

Enhancement of synaptic transmission by HPC‐1 antibody in the cultured hippocampal neuron

K. Akagawa, Y. Tsuchimoto, K. Yamaguchi, 1997, Neuroreport.

ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion.

K. Akagawa, Kei Suga, Ayako Saito, 2015, Experimental cell research.

Identification and characterisation of cell types accumulating GABA in rat retinal cultures using cell type specific monoclonal antibodies

C. Barnstable, K. Akagawa, 1987, Brain Research.