Siddhartha Roy

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A Cooperative Stochastic Model of Gene Expression

S. S. Manna, Siddhartha Roy, I. Bose, 2001, cond-mat/0105226.

Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300.

T. Kundu, J. Sengupta, Siddhartha Roy, 2019, Biochemistry.

Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions.

Siddhartha Roy, Gitashri Naiya, P. Raha, 2016, Physical chemistry chemical physics : PCCP.

Structural features of human histone acetyltransferase p300 and its complex with p53

Siddhartha Banerjee, T. Kundu, Siddhartha Roy, 2012, FEBS letters.

Specific DNA sequences allosterically enhance protein-protein interaction in a transcription factor through modulation of protein dynamics: implications for specificity of gene regulation.

Siddhartha Roy, R. Ghosh, M. Mondal, 2017, Physical chemistry chemical physics : PCCP.

Differential recognition of phosphorylated transactivation domains of p53 by different p300 domains.

K. Sakaguchi, T. Kundu, Siddhartha Roy, 2008, Journal of molecular biology.

Multiphasic denaturation of the λ repressor by urea and its implications for the repressor structure

Siddhartha Roy, S. Roy, U. Banik, 1992 .

Multifunctional enzymes and evolution of biosynthetic pathways: Retro‐evolution by jumps

Siddhartha Roy, 1999, Proteins.

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression*

E. Appella, Siddhartha Roy, O. Gozani, 2010, The Journal of Biological Chemistry.

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

Fei Yang, A. Sahin, Siddhartha Roy, 2019, Nature Communications.

Exhaled breath condensate metabolome clusters for endotype discovery in asthma

R. Lodha, S. Kabra, Siddhartha Roy, 2017, Journal of Translational Medicine.

Indirect read-out of the promoter DNA by RNA polymerase in the closed complex

Siddhartha Roy, N. Roy, Indrani Bera, 2012, Nucleic acids research.

Determination of RNA polymerase binding and isomerization parameters by measuring abortive initiations.

Siddhartha Roy, 2003, Methods in enzymology.

Role of C-terminal residues in oligomerization and stability of lambda CII: implications for lysis-lysogeny decision of the phage.

Siddhartha Roy, A. Datta, P. Parrack, 2005, Journal of molecular biology.

Disorder-order transition of lambda CII promoted by low concentrations of guanidine hydrochloride suggests a stable core and a flexible C-terminus.

Siddhartha Roy, A. Datta, P. Parrack, 2003, European journal of biochemistry.

Gene regulatory networks and epigenetic modifications in cell differentiation

T. Kundu, Siddhartha Roy, T. K. Kundu, 2014, IUBMB life.

SMAR1 regulates free radical stress through modulation of AKR1a4 enzyme activity.

S. Chattopadhyay, Siddhartha Roy, L. Pavithra, 2010, The international journal of biochemistry & cell biology.

Stochastic Simulation of Gene Expression in a Single Cell

Siddhartha Roy, I. Bose, R. Karmakar, 2002, cond-mat/0210183.

X-ray studies on crystalline complexes involving amino acids and peptides. XLII. Adipic acid complexes of L- and DL-arginine and supramolecular association in arginine-dicarboxylic acid complexes.

M. Vijayan, Siddhartha Roy, D. Singh, 2005, Acta crystallographica. Section B, Structural science.

X-ray studies on crystalline complexes involving amino acids and peptides. XLI. Commonalities in aggregation and conformation revealed by the crystal structures of the pimelic acid complexes of L-arginine and DL-lysine.

M. Vijayan, Siddhartha Roy, N. Saraswathi, 2003, Acta crystallographica. Section B, Structural science.

Chemical genomics: Understanding gene regulatory networks in differentiation and disease

T. Kundu, Siddhartha Roy, 2021 .

Enhanced basepair dynamics pre-disposes protein-assisted flips of key bases in DNA strand separation during transcription initiation.

S. Chakrabarti, Siddhartha Roy, R. Ghosh, 2018, Physical chemistry chemical physics : PCCP.

Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain.

R. Ismagilov, M. Cleary, A. Selezneva, 2010, Journal of molecular biology.

Metabolomic signatures in nuclear magnetic resonance spectra of exhaled breath condensate identify asthma

R. Lodha, S. Kabra, Siddhartha Roy, 2012, European Respiratory Journal.

DNA base sequence specificity through partial intercalation: DFT-D based energy analysis of molecular dynamics snapshots.

Siddhartha Roy, D. Bhattacharyya, Soumi Das, 2020, Journal of molecular graphics & modelling.

A synthetic peptide mimic of λ-Cro shows sequence-specific binding in vitro and in vivo.

Siddhartha Roy, Abhishek Mazumder, K. Roy, 2012, ACS chemical biology.

Chemical modifications of genome

T. Kundu, Siddhartha Roy, 2021 .

Human Placental Extract Mediated Inhibition of Proteinase K: Implications of Heparin and Glycoproteins in Wound Physiology

Siddhartha Roy, K. Sharma, D. Bhattacharyya, 2014, Journal of cellular physiology.

Peptide-Protein Interactions Suggest That Acetylation of Lysines 381 and 382 of p53 Is Important for Positive Coactivator 4-p53 Interaction

T. Kundu, Siddhartha Roy, Snehajyoti Chatterjee, 2011, The Journal of Biological Chemistry.

A Constrained Helical Peptide Against S100A4 Inhibits Cell Motility in Tumor Cells

T. Kundu, Siddhartha Roy, Stephanie Kaypee, 2015, Chemical biology & drug design.

Human testis–specific Y-encoded protein-like protein 5 is a histone H3/H4-specific chaperone that facilitates histone deposition in vitro

Siddhartha Roy, Chandrima Das, Anirban Dasgupta, 2022, The Journal of biological chemistry.

A peptide-based synthetic transcription factor selectively down-regulates the proto-oncogene CFOS in tumour cells and inhibits proliferation.

Siddhartha Roy, Madhumita Chakraborty, 2016, Chemical communications.

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation

Siddhartha Roy, M. Churchill, J. Tyler, 2014, Proceedings of the National Academy of Sciences.

Genes, genomes, and genome dynamics

Siddhartha Roy, T. K. Kundu, 2021 .

Selective Recognition of H3.1K36 Dimethylation/H4K16 Acetylation Facilitates the Regulation of All-trans-retinoic Acid (ATRA)-responsive Genes by Putative Chromatin Reader ZMYND8*

Siddhartha Roy, Chandrima Das, Santanu Adhikary, 2015, The Journal of Biological Chemistry.

Switching DNA-binding specificity by unnatural amino acid substitution

Siddhartha Roy, A. Maiti, 2005, Nucleic acids research.

A Peptide‐PNA Hybrid Beacon for Sensitive Detection of Protein Biomarkers in Biological Fluids

Siddhartha Roy, Amlanjyoti Dhar, S. Mallick, 2020, Chembiochem : a European journal of chemical biology.

Fluorescence energy transfer measurement of distances between ligand binding sites of tubulin and its implication for protein‐protein interaction

Siddhartha Roy, B. Bhattacharyya, A. Bhattacharya, 1996, Protein science : a publication of the Protein Society.

Antagonists of Hsp16.3, a Low-Molecular-Weight Mycobacterial Chaperone and Virulence Factor, Derived from Phage-Displayed Peptide Libraries

Siddhartha Roy, A. Saha, B. Bhattacharyya, 2005, Applied and Environmental Microbiology.

A convenient asymmetric synthesis of the octalactin lactone

Siddhartha Roy, S. Chattopadhyay, A. Chattopadhyay, 2008 .

Epigenetic regulation of Fructose‐1,6‐bisphosphatase 1 by host transcription factor Speckled 110 kDa during hepatitis B virus infection

Siddhartha Roy, P. Mondal, Isha Sengupta, 2022, The FEBS journal.

Structural insight into p53 recognition by the 53BP1 tandem Tudor domain.

E. Appella, Siddhartha Roy, J. Nix, 2010, Journal of molecular biology.

Cloning, expression, purification, crystallization and preliminary X-ray analysis of peptidyl-tRNA hydrolase from Mycobacterium tuberculosis.

M. Vijayan, Siddhartha Roy, M. Selvaraj, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Understanding the role of non‐Watson‐Crick base pairs in DNA–protein recognition: Structural and energetic aspects using crystallographic database analysis and quantum chemical calculation

Siddhartha Roy, D. Bhattacharyya, Soumi Das, 2022, Biopolymers.

Peptide based Molecules as Protein-Protein Interaction Inhibitors: Tools for Chemical Genetics and Therapy

Siddhartha Roy, Piya Ghosh, N. Roy, 2012 .

Fluorescence quenching methods to study protein-nucleic acid interactions.

Siddhartha Roy, 2004, Methods in enzymology.

Identifying the Risk of Swallowing-Related Pulmonary Complications in Older Patients With Hip Fracture.

R. Neviaser, Siddhartha Roy, J. O’Brien, 2016, Orthopedics.

Specific Sequence of a Beta Turn in Human La Protein May Contribute to Species Specificity of Hepatitis C Virus

Saumitra Das, Siddhartha Roy, U. Ray, 2014, Journal of Virology.

International symposium on challenges in chemical biology: toward the formation of Chemical Biology Society of India.

T. Kundu, Siddhartha Roy, P. Jaisankar, 2013, ACS chemical biology.

Gal repressor-operator-HU ternary complex: pathway of repressosome formation.

E. Dimitriadis, Siddhartha Roy, Marc S. Lewis, 2005, Biochemistry.

Prevalence and risk factors of asthma and wheeze in school-going children in Lucknow, North India.

S. Awasthi, Siddhartha Roy, S. Awasthi, 2004, Indian pediatrics.

Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.

T. Kundu, Siddhartha Roy, V. Swaminathan, 2007, Chemistry & biology.

Structural Determinant of Human La Protein Critical for Internal Initiation of Translation of Hepatitis C Virus RNA

Saumitra Das, Siddhartha Roy, T. Mondal, 2008, Journal of Virology.

An efficient asymmetric synthesis of (S)-2-cyclohexyl-2-phenylglycolic acid, the acid segment of oxybutynin

Siddhartha Roy, S. Chattopadhyay, Anubha Sharma, 2006 .

Metal-dependent reaction tuning with cyclopentylmetal reagents: application to the asymmetric synthesis of (+)-alpha-conhydrine and (S)-2-cyclopentyl-2-phenylglycolic acid.

Siddhartha Roy, S. Chattopadhyay, Anubha Sharma, 2009, Chemistry.

Anticancer drug mithramycin interacts with core histones: An additional mode of action of the DNA groove binder

A. Banerjee, Siddhartha Roy, K. Jana, 2014, FEBS open bio.

An Efficient Asymmetric Route to Tertiary Carbinols: Synthesis of (R)-Mevalonolactone

Siddhartha Roy, Siddhartha Roy, Subrata Chattopadhyay, 2007 .

Natural products: promising resources for cancer drug discovery.

Siddhartha Roy, Mrinal K. Ghosh, C. Mandal, 2012, Anti-cancer agents in medicinal chemistry.

Aib-based peptide backbone as scaffolds for helical peptide mimics.

Siddhartha Roy, P. Chène, G. Basu, 2002, The journal of peptide research : official journal of the American Peptide Society.

Hydroxychavicol, a Piper betle leaf component, induces apoptosis of CML cells through mitochondrial reactive oxygen species‐dependent JNK and endothelial nitric oxide synthase activation and overrides imatinib resistance

Siddhartha Roy, K. Joshi, V. Shinde, 2012, Cancer science.

X-ray studies of crystalline complexes involving amino acids and peptides. XLIV. Invariant features of supramolecular association and chiral effects in the complexes of arginine and lysine with tartaric acid.

M. Vijayan, Siddhartha Roy, M. Selvaraj, 2007, Acta crystallographica. Section B, Structural science.

X-ray studies of crystalline complexes involving amino acids and peptides. XLIII. Adipic acid complexes of L- and DL-lysine.

M. Vijayan, Siddhartha Roy, Alok K. Sharma, 2006, Acta crystallographica. Section C, Crystal structure communications.

Drug discovery research in India: current state and future prospects.

T. Kundu, Siddhartha Roy, T. Balganesh, 2014, ACS medicinal chemistry letters.

Activation and Repression of Transcription by Differential Contact: Two Sides of a Coin*

Siddhartha Roy, S. Adhya, S. Garges, 1998, The Journal of Biological Chemistry.

Asynchronous basepair openings in transcription initiation: CRP enhances the rate‐limiting step

Siddhartha Roy, S. Adhya, Mofang Liu, 2004, The EMBO journal.

Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization

A. Motsinger-Reif, Siddhartha Roy, M. Breen, 2015, Chromosome Research.

Proteins: Structure, Function, and Engineering

Siddhartha Roy, B. Biswas, 1995, Subcellular Biochemistry.

Structural studies on the second Mycobacterium smegmatis Dps: invariant and variable features of structure, assembly and function.

M. Vijayan, Siddhartha Roy, D. Chatterji, 2008, Journal of molecular biology.

Role of N and C-terminal tails in DNA binding and assembly in Dps: structural studies of Mycobacterium smegmatis Dps deletion mutants.

M. Vijayan, Siddhartha Roy, K. Sekar, 2007, Journal of molecular biology.

New enzymic synthesis of 2'-deoxynucleoside-2',2'-d2 and the determination of sugar ring flexibility by solid-state deuterium NMR

D. Torchia, Y. Hiyama, Siddhartha Roy, 1986 .

Solid-state deuterium NMR study of thymidine. Base rigidity and ribose ring flexibility in deoxynucleosides

D. Torchia, Y. Hiyama, Siddhartha Roy, 1989 .

[7-15N]guanosine-labeled oligonucleotides as a nuclear magnetic resonance probe for protein-nucleic acid interaction in the major groove

A. Redfield, Siddhartha Roy, W. Massefski, 1990 .

A chimaeric glutamyl:glutaminyl-tRNA synthetase: implications for evolution.

Siddhartha Roy, R. Saha, G. Basu, 2009, The Biochemical journal.

The zinc-binding site of a class I aminoacyl-tRNA synthetase is a SWIM domain that modulates amino acid binding via the tRNA acceptor arm.

Siddhartha Roy, Sheng-Xiang Lin, R. Banerjee, 2004, European journal of biochemistry.

Deuterium nuclear magnetic resonance of oriented DNA fibers

D. Torchia, Y. Hiyama, Siddhartha Roy, 1987 .

Conformation of the oligonucleotide d(AAAAAATTTTTT)2 by two‐dimensional nuclear overhauser effect spectroscopy and its relevance to poly(dA) · poly(dT)

Siddhartha Roy, J. S. Cohen, B. Borah, 1987, Biopolymers.

Solid-State 2H NMR Study of Thymidine. Base Rigidity and Ribose Ring Flexibility in Deoxynucleosides.

D. Torchia, Y. Hiyama, Siddhartha Roy, 1990 .

Kinetics of Transcription Initiation at lacP1

Siddhartha Roy, Siddhartha Roy, Smita S. Patel, 2003, Journal of Biological Chemistry.

Structural plasticity and enzyme action: crystal structures of mycobacterium tuberculosis peptidyl-tRNA hydrolase.

M. Vijayan, Siddhartha Roy, M. Selvaraj, 2007, Journal of molecular biology.

Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1

A. Yasui, Siddhartha Roy, J. Nickoloff, 2012, Nature Structural &Molecular Biology.

Metabolic and Morphological Differences between Rapidly Proliferating Cancerous and Normal Breast Epithelial Cells

Adam L. Meadows, H. Blanch, D. Clark, 2008, Biotechnology progress.

The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis

A. Dutt, T. Kundu, Siddhartha Roy, 2019, The Journal of Biological Chemistry.

Implications of Enhancer Transcription and eRNAs in Cancer

Siddhartha Roy, Shrikanth S. Gadad, Chandrima Das, 2021, Cancer Research.

ZMYND8 suppresses MAPT213 LncRNA transcription to promote neuronal differentiation

Siddhartha Roy, Shrikanth S. Gadad, Ramesh Choudhari, 2022, Cell Death & Disease.

Cellular and molecular mechanisms of cigarette smoke-induced lung damage and prevention by vitamin C

Siddhartha Roy, Arunava Ghosh, H. Koley, 2008, Journal of Inflammation.

Monomer and dimer of Chandipura virus unphosphorylated P-protein binds leader RNA differently: implications for viral RNA synthesis.

Siddhartha Roy, Smarajit Polley, D. Chattopadhyay, 2004, Journal of molecular biology.

Constrained α-Helical Peptides as Inhibitors of Protein-Protein and Protein-DNA Interactions

Siddhartha Roy, Piya Ghosh, Gitashri Naiya, 2018, Biomedicines.

Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization

Siddhartha Roy, Shrikanth S. Gadad, Chandrima Das, 2020, Cell Death & Disease.

A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual-histone binding function

Siddhartha Roy, Chandrima Das, P. Chakrabarti, 2020, Journal of Biosciences.

SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription.

K. Sakaguchi, S. Chattopadhyay, Siddhartha Roy, 2009, Journal of molecular biology.

Small cationic protein from a marine turtle has β‐defensin‐like fold and antibacterial and antiviral activity

N. K. Sinha, Siddhartha Roy, D. Roy, 2006, Proteins.

Genetic heterogeneity beyond CYP2C8*3 does not explain differential sensitivity to paclitaxel-induced neuropathy

L. Carey, H. McLeod, A. Motsinger-Reif, 2014, Breast Cancer Research and Treatment.

Dual histone reader ZMYND8 inhibits cancer cell invasion by positively regulating epithelial genes.

Siddhartha Roy, Chandrima Das, P. Chakrabarti, 2017, The Biochemical journal.

A peptide targeted against phosphoprotein and leader RNA interaction inhibits growth of Chandipura virus -- an emerging rhabdovirus.

Siddhartha Roy, Smarajit Polley, D. Chattopadhyay, 2013, Antiviral research.

N-protein-RNA interaction is a drug target in a negative strand RNA virus

Siddhartha Roy, D. Chattopadhyay, P. Chakraborty, 2021, Virus Research.

P-protein of Chandipura virus is an N-protein-specific chaperone that acts at the nucleation stage.

Dhrubajyoti Chattopadhyay, Siddhartha Roy, Siddhartha Roy, 2004, Biochemistry.

Effect of Osmolytes and Chaperone-like Action of P-protein on Folding of Nucleocapsid Protein of Chandipura Virus*

Siddhartha Roy, S. Roy, D. Chattopadhyay, 2001, The Journal of Biological Chemistry.

X-ray analysis of Mycobacterium smegmatis Dps and a comparative study involving other Dps and Dps-like molecules.

M. Vijayan, Siddhartha Roy, K. Sekar, 2004, Journal of molecular biology.

GalR represses galP1 by inhibiting the rate-determining open complex formation through RNA polymerase contact: a GalR negative control mutant.

Siddhartha Roy, S. Semsey, S. Adhya, 2004, Journal of molecular biology.

Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum.

Siddhartha Roy, V. Seshadri, Chandrima Das, 2021, The Biochemical journal.

Chemical principles of DNA sequence recognition and gene regulation

T. Kundu, Siddhartha Roy, 2021 .

DNA-Bound p53-DNA-Binding Domain Interconverts between Multiple Conformations: Implications for Partner Protein Recognition.

Siddhartha Roy, Sujoy Mukherjee, S. Bhattacharjee, 2021, The journal of physical chemistry. B.

Reversal of drug resistance by disruption of a Gain-of-Function mutant p53 and transcriptional co-activator PC4 interaction

Kumar Singha Roy, Siddhartha Roy, S. Roychoudhury, 2023, bioRxiv.

Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation

T. Kundu, Siddhartha Roy, Stephanie Kaypee, 2018, iScience.

Multifunctional transcriptional coactivator PC4 is a global co-regulator of p53-dependent stress response and gene regulation.

T. Kundu, Siddhartha Roy, S. Biswas, 2019, Journal of biochemistry.

Bi‐stability of the master gene regulatory network of the common dendritic precursor cell: Implications for cell differentiation

Siddhartha Roy, S. Banik, Mintu Nandi, 2020, IUBMB life.

A peptide-based synthetic transcription factor selectively activates transcription in a mammalian cell.

Siddhartha Roy, Piya Ghosh, Gitashri Naiya, 2018, Chemical communications.

Molecular characterization of substrate‐induced ubiquitin transfer by UBR7‐PHD finger, a newly identified histone H2BK120 ubiquitin ligase

A. Dasgupta, Siddhartha Roy, Chandrima Das, 2021, The FEBS journal.

Evolution of DNA binding motifs and operators.

Ashutosh Sahu, Siddhartha Roy, Siddhartha Roy, 2002, Gene.

Recognition of different DNA sequences by a DNA‐binding protein alters protein dynamics differentially

Siddhartha Roy, Subrata Batabyal, Abhishek Mazumder, 2012, FEBS letters.

Solvation change and ion release during aminoacylation by aminoacyl-tRNA synthetases.

Siddhartha Roy, R. Saha, Soumi Guha, 2003, Nucleic acids research.

A mimotope attached to an ITIM-SHP-1 interaction inhibitory peptide boosts immune response and efficacy.

Siddhartha Roy, Syamal Roy, Koushik Roy, 2021, RSC medicinal chemistry.

Ellagic Acid, a Dietary Polyphenol, Inhibits Tautomerase Activity of Human Macrophage Migration Inhibitory Factor and Its Pro-inflammatory Responses in Human Peripheral Blood Mononuclear Cells.

U. Bandyopadhyay, Siddhartha Roy, M. S. Iqbal, 2015, Journal of agricultural and food chemistry.

The role of the catalytic domain of E. coli GluRS in tRNAGln discrimination

Siddhartha Roy, R. Saha, R. Banerjee, 2009, FEBS letters.

Elucidation of genome sequence and functional architecture by chemical biology approach

T. Kundu, Siddhartha Roy, 2021 .

Crystallization and preliminary X-ray diffraction analysis of Mycobacterium smegmatis Dps.

M. Vijayan, Siddhartha Roy, K. Sekar, 2003, Acta crystallographica. Section D, Biological crystallography.

Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain*

Siddhartha Roy, T. Kutateladze, R. Stahelin, 2011, The Journal of Biological Chemistry.

An integrative view of chemical biology

Siddhartha Roy, Tapas K. Kundu, T. Kundu, 2021 .

On the use of 2-aminopurine as a probe for base pair opening during transcription initiation.

Siddhartha Roy, 2003, Methods in enzymology.

Glutamate Counteracts the Denaturing Effect of Urea through Its Effect on the Denatured State*

Siddhartha Roy, A. Mandal, R. Banerjee, 2003, Journal of Biological Chemistry.

Unusual asymmetry of methyl deuterium EFG in thymine: a solid state deuterium NMR and ab initio MO study

D. Torchia, Y. Hiyama, Siddhartha Roy, 1987 .

Unusual Asymmetry of Methyl 2H EFG in Thymine: A Solid State Deuterium NMR and ab initio MO Study.

D. Torchia, Y. Hiyama, Siddhartha Roy, 1987 .

Chemical biology research in India.

T. Kundu, Siddhartha Roy, B. Selvi, 2011, ACS chemical biology.

A “master” in base unpairing during isomerization of a promoter upon RNA polymerase binding

Siddhartha Roy, S. Adhya, Heon-Man Lim, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Role of the carboxy‐termini of tubulin on its chaperone‐like activity

Siddhartha Roy, S. Roy, B. Bhattacharyya, 2001, Proteins.

DnaK-Sigma 32 Interaction Is Temperature-dependent

Siddhartha Roy, Ruchira Chattopadhyay, 2002, The Journal of Biological Chemistry.

Ligand specificity and ligand‐induced conformational change in gal repressor

Siddhartha Roy, Kajari Ghosh, Amlanjyoti Dhar, 2002, Proteins.

Specific small-molecule activator of Aurora kinase A induces autophosphorylation in a cell-free system.

S. Agrawal, T. Kundu, Siddhartha Roy, 2008, Journal of medicinal chemistry.

Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex

Siddhartha Roy, Chandrima Das, D. K. Srivastava, 2017, The Journal of Biological Chemistry.

TCF19 promotes cell proliferation through binding to the histone H3K4me3 mark.

Siddhartha Roy, T. Kutateladze, Shrikanth S. Gadad, 2019, Biochemistry.

A small HDM2 antagonist peptide and a USP7 inhibitor synergistically inhibit the p53‐HDM2‐USP7 circuit

Siddhartha Roy, N. Roy, Gitashri Naiya, 2023, Chemical biology & drug design.

Solvation dynamics in the molten globule state of a protein

Siddhartha Roy, K. Bhattacharyya, Arnab Halder, 2003 .

Solvation Dynamics of a Probe Covalently Bound to a Protein and in an AOT Microemulsion: 4-(N-Bromoacetylamino)-Phthalimide

Siddhartha Roy, K. Bhattacharyya, A. Mandal, 2002 .

Ultrafast differential flexibility of Cro-protein binding domains of two operator DNAs with different sequences.

Siddhartha Roy, R. Ghosh, Susobhan Choudhury, 2016, Physical chemistry chemical physics : PCCP.

Slow solvation dynamics at the active site of an enzyme: implications for catalysis.

Siddhartha Roy, Soumi Guha, K. Bhattacharyya, 2005, Biochemistry.

Allosteric Activation of p300 Autoacetylation by the Tumor Suppressor p53

T. Kundu, J. Sengupta, Siddhartha Roy, 2017, bioRxiv.

A Potent Conformation-Constrained Synthetic Peptide Mimic of a Homeodomain Selectively Regulates Target Genes in Cells.

Siddhartha Roy, Susobhan Choudhury, S. Pal, 2018, ACS chemical biology.

Epigenetic Reprogramming of the Glucose Metabolic Pathways by the Chromatin Effectors During Cancer.

Siddhartha Roy, P. Mondal, C. Das, 2022, Sub-cellular biochemistry.

Exhaled breath condensate metabolome clusters for endotype discovery in asthma

R. Lodha, S. Kabra, Siddhartha Roy, 2017, Journal of Translational Medicine.

Modulation of Ultrafast Conformational Dynamics in Allosteric Interaction of Gal Repressor Protein with Different Operator DNA Sequences

Siddhartha Roy, Gitashri Naiya, Susobhan Choudhury, 2016, Chembiochem : a European journal of chemical biology.

Effect of Phosphorylation on the Structure and Fold of Transactivation Domain of p53*

K. Sakaguchi, T. Kundu, Siddhartha Roy, 2002, The Journal of Biological Chemistry.

Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

Fei Yang, A. Sahin, Siddhartha Roy, 2019, Nature Communications.

Chemical biology: Drug discovery targeting the functional genome

T. Kundu, Siddhartha Roy, 2021 .

Conformational perturbation due to an extra adenosine in a self‐complementary oligodeoxynucleotide duplex

E. Appella, Siddhartha Roy, V. Sklenar, 1987, Biopolymers.

Methods: Tools for studying genomes and gene functions in intact cells

T. Kundu, Siddhartha Roy, 2021 .

Conformational adaptation in the E. coli sigma 32 protein in response to heat shock.

S. Chakrabarti, Siddhartha Roy, Abhijit Chakraborty, 2014, The journal of physical chemistry. B.

Simultaneous inhibition of key growth pathways in melanoma cells and tumor regression by a designed bidentate constrained helical peptide

S. Chattopadhyay, Siddhartha Roy, Piya Ghosh, 2014, Biopolymers.

A cognate tRNA specific conformational change in glutaminyl‐tRNA synthetase and its implication for specificity

Siddhartha Roy, T. Bhattacharyya, S. Bhattacharyya, 1998, Protein science : a publication of the Protein Society.

A genetic network that balances two outcomes utilizes asymmetric recognition of operator sites.

P. Chakrabarti, Siddhartha Roy, Abhishek Mazumder, 2012, Biophysical journal.

Alternative sigma factors in the free state are equilibrium mixtures of open and compact conformations.

Siddhartha Roy, P. Raha, S. Chattopadhyay, 2010, Biochemistry.

A functional loop spanning distant domains of glutaminyl-tRNA synthetase also stabilizes a molten globule state.

D. Söll, Siddhartha Roy, R. Saha, 2012, Biochemistry.

Insights on the disruption of the complex between human positive coactivator 4 and p53 by small molecules.

Siddhartha Roy, D. Chakravorty, Smarajit Polley, 2021, Biochemical and biophysical research communications.

Interrogation of polymorphisms in drug metabolism or transport genes and peripheral neuropathy during paclitaxel treatment.

L. Carey, H. McLeod, A. Motsinger-Reif, 2012 .

Optimal design of metabolic flux analysis experiments for anchorage‐dependent mammalian cells using a cellular automaton model

Adam L. Meadows, H. Blanch, D. Clark, 2007, Biotechnology and bioengineering.

Role of zinc in tRNA-acceptor stem binding by glutamyl-tRNA synthetase from E.coli: a molecular modeling study.

Siddhartha Roy, A. Bothra, C. Mandal, 1997, Journal of biomolecular structure & dynamics.

High-affinity quasi-specific sites in the genome: how the DNA-binding proteins cope with them.

Siddhartha Roy, P. Raha, J. Chakrabarti, 2011, Biophysical journal.

Structural features of human histone acetyltransferase p300 and its complex with p53

T. Kundu, Siddhartha Roy, N. Roy, 2012, FEBS letters.

Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization

A. Motsinger-Reif, Siddhartha Roy, M. Breen, 2014, Chromosome Research.