D. Harrison

Igor Goryanin, Galina Lebedeva, Simon P. Langdon, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Features of the reversible sensitivity-resistance transition in PI3K/PTEN/AKT signalling network after HER2 inhibition.

David J Harrison, Alexey Goltsov, James Bown, 2012, Cellular signalling.

Compensatory effects in the PI3K/PTEN/AKT signaling network following receptor tyrosine kinase inhibition.

Igor Goryanin, David J Harrison, Alexey Goltsov, 2011, Cellular signalling.

Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells.

Hilal S. Khalil, J. Bown, D. Harrison, 2015, Journal of biotechnology.

Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer

P. Caie, A. Turnbull, A. Oniscu, 2014, Journal of Translational Medicine.

Automated Analysis of Lymphocytic Infiltration, Tumor Budding, and Their Spatial Relationship Improves Prognostic Accuracy in Colorectal Cancer

Peter D Caie, David J Harrison, Hideki Ueno, 2019, Cancer Immunology Research.

Desmoplastic Reaction as the Most Significant Prognostic Feature For Disease-specific Survival in Stage II Colorectal Cancer

H. Ueno, P. Caie, D. Harrison, 2019 .

Automated tumour budding quantification by machine learning augments TNM staging in muscle-invasive bladder cancer prognosis

Nicolas Brieu, Günter Schmidt, David J. Harrison, 2019, Scientific Reports.

Identification of Immunological Features Enables Survival Prediction of Muscle-Invasive Bladder Cancer Patients Using Machine Learning

Ognjen Arandjelovic, P. Caie, D. Harrison, 2020, bioRxiv.

Inhibition of tumour necrosis factor alpha does not prevent experimental paracetamol‐induced hepatic necrosis

R. Strieter, D. Harrison, S. Kunkel, 2000, The Journal of pathology.

Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion.

P. Hayes, W. Bickmore, K. Samuel, 2003, Gastroenterology.

Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

Alexander L. R. Lubbock, I. Overton, D. Harrison, 2017, BMC Medicine.

Systems biology reveals new strategies for personalizing cancer medicine and confirms the role of PTEN in resistance to trastuzumab.

Igor Goryanin, Stuart Moodie, Galina Lebedeva, 2009, Cancer research.

Diversity of Matriptase Expression Level and Function in Breast Cancer

D. Harrison, V. Brunton, M. Frame, 2012, PloS one.

Dynamic computational modeling in the search for better breast cancer drug therapy.

I. Goryanin, S. Moodie, D. Harrison, 2007, Pharmacogenomics.

Expression of the developmental Sonic hedgehog (Shh) signalling pathway is up‐regulated in chronic lung fibrosis and the Shh receptor patched 1 is present in circulating T lymphocytes

C. Haslett, J. Lamb, D. Harrison, 2003, The Journal of pathology.

Coexpression of RTI40 with alveolar epithelial type II cell proteins in lungs following injury: identification of alveolar intermediate cell types.

D. Harrison, M. Beers, S. Mckechnie, 2005, American journal of physiology. Lung cellular and molecular physiology.

Genetic polymorphisms of cytochrome p4502E1 and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a white population: a study and literature review, including meta-analysis

D. Harrison, K. Simpson, N. Wong, 2000, Molecular pathology : MP.

Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors.

C. Campbell, D. Harrison, M. Barańska, 2015, The Analyst.

Targeted SERS nanosensors measure physicochemical gradients and free energy changes in live 3D tumor spheroids.

W. Nailon, C. Campbell, D. Harrison, 2016, Nanoscale.

Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer.

C. Ward, D. Harrison, P. Mullen, 2014, Biochemical Society transactions.

Determining tamoxifen sensitivity using primary breast cancer tissue in collagen-based three-dimensional culture.

D. Harrison, Jeremy S. Thomas, J. Dixon, 2012, Biomaterials.

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

T. Ried, G. Meijer, B. Carvalho, 2019, Molecular aspects of medicine.

Effects of heterozygosity for the Rb-1t19neo allele in the mouse.

D. Harrison, A. Clarke, J. Armstrong, 1995, Oncogene.

Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy.

M. Cummings, D. Harrison, A. Clarke, 1995, Oncogene.

Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.

D. Harrison, J. Hayes, T. O'connor, 1999, The Biochemical journal.

Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress.

W. MacNee, I. Rahman, D. Harrison, 1995, The American journal of physiology.

Phenobarbitone-induced ploidy changes in liver occur independently of p53.

D. Harrison, S. Gould, N. Sansom, 2001, Toxicology letters.

p53‐independent DNA repair and cell cycle arrest in embryonic stem cells

D. Harrison, A. Wyllie, A. Clarke, 1998, FEBS letters.

ERβ isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates

D. Harrison, R. Malcomson, D. Jodrell, 2005, The Journal of pathology.

Direct Detection of eae-Positive Bacteria in Human and Veterinary Colorectal Specimens by PCR

D. Harrison, S. McOrist, A. Hubbard, 1998, Journal of Clinical Microbiology.

Natural disasters and man-made responses: are we protecting environmental health?

D. Harrison, K. Breslin, H. Klys, 1993, Environmental Health Perspectives.

Laparoscopy and histology in the diagnosis of chronic liver disease.

P. Hayes, R. Jalan, D. Harrison, 1995, QJM : monthly journal of the Association of Physicians.

Variation in the expression of Mu-class glutathione S-transferase isoenzymes from human skeletal muscle. Evidence for the existence of heterodimers.

D. Harrison, J. Hayes, A. Cronshaw, 1991, Biochemical Journal.

Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on‐target inhibitors Rapamycin, BEZ235, and LY294002

J. Bown, D. Harrison, S. Langdon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Explorer TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p 53 , p 21 ( Cip 1 ) or Rb status

D. Harrison, S. Prost, C. Bellamy, 2017 .

Reply to: discordant expression of molecular markers between primary and nodal metastases: a histopathological manifestation of the 'self (stem cell)-seeding' nature of breast cancer disease?

D. Harrison, D. Faratian, J. Thomas, 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

Colm E. Nestor, R. Kitchen, B. Ramsahoye, 2012, Genome Biology.

Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer

Alexander L. R. Lubbock, D. Berney, I. Overton, 2015, Clinical Cancer Research.

Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

Alexander L. R. Lubbock, D. Berney, I. Overton, 2014, European urology.

Multidisciplinary urological engagement in translational renal cancer research

J. Larkin, D. Nicol, C. Swanton, 2014, BJU international.

Tissue-specific tolerance in fatal Covid-19

Colin Smith, J. Baillie, K. Dhaliwal, 2020, medRxiv.

Differential expression of hDAB2IPA and hDAB2IPB in normal tissues and promoter methylation of hDAB2IPA in hepatocellular carcinoma.

M. Salto‐Tellez, J. Ross, D. Harrison, 2007, Journal of hepatology.

Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.

C. Supuran, A. Scozzafava, J. Winum, 2012, Bioorganic & medicinal chemistry letters.

Raman spectroscopy investigation of biochemical changes in tumor spheroids with aging and after treatment with staurosporine

C. Campbell, D. Harrison, L. Jamieson, 2019, Journal of biophotonics.

Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

D. Deforce, D. Harrison, Christophe Van Neste, 2016, Oncotarget.

Absence of p53 in Clara cells favours multinucleation and loss of cell cycle arrest

S. O'Dea, D. Harrison, A. Clarke, 2002, BMC Cell Biology.

Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.

W. Kolch, O. Sansom, S. Hagan, 2008, Experimental cell research.

MBD4 Interacts With and Recruits USP7 to Heterochromatic Foci

R. Meehan, D. Harrison, Huan Meng, 2015, Journal of cellular biochemistry.

Fibronectin via Integrin and Decreases Attachment to In vivo Tumorigenicity Gene Expression Abolishes Ovarian Cancer

A. Paige, H. Gabra, C. Ward, 2009 .

Effect of extracellular matrix (ECM) on Clara cell differentiation through P21 regulation

D. Harrison, R. Blundell, 2007 .

Routinely Obtained Diagnostic Material as a Source of RNA for Personalized Medicine in Lung Cancer Patients

D. Harrison, W. Wallace, T. Andrews, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

p21Waf1/Cip1 REGULATES PROLIFERATION AND APOPTOSIS IN AIRWAY EPITHELIAL CELLS AND ALTERNATIVE FORMS HAVE ALTERED BINDING ACTIVITIES

S. O'Dea, D. Harrison, R. Blundell, 2004, Experimental lung research.

Altered DNA repair and dysregulation of p53 in IRF‐1 null hepatocytes

D. Harrison, S. Prost, C. Bellamy, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MBD1, MBD2 and CGBP genes at chromosome 18q21 are infrequently mutated in human colon and lung cancers

A. Bird, D. Harrison, A. Peter, 2003, Oncogene.

Clinical significance of intrahepatic hepatitis C virus levels in patients with chronic HCV infection

P. Simmonds, P. Hayes, D. Harrison, 1998, Gut.

Glutathione S-transferase expression in fetal kidney and Wilms' tumour.

D. Harrison, L. Hallam, J. Lauder, 1990, British Journal of Cancer.

An Analytical Approach Differentiates Between Individual and Collective Cancer Invasion

V. Smith, M. Edward, D. Harrison, 2011, Analytical cellular pathology.

Emphysema: the challenge of the remodelled lung

D. Harrison, W. Wallace, R. Blundell, 2004, The Journal of pathology.

Explorer Independent regulation of P 53 stabilisation and activation after Rb deletion in primary epithelial cells

D. Harrison, S. Prost, C. Bellamy, 2017 .

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

D. Harrison, Rui Huang, P. Mullen, 2015, Oncotarget.

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene.

C. Purdie, D. Harrison, S. Howie, 1994, Oncogene.

Long-term Culture of Human Breast Cancer Specimens and Their Analysis Using Optical Projection Tomography

D. Harrison, J. Dixon, A. Leeper, 2011, Journal of visualized experiments : JoVE.

The origin of cells in the glomerular crescent investigated by the use of monoclonal antibodies

D. Harrison, M. K. Macdonald, D. Harrison, 1986, Histopathology.

N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions

C. Smith, D. Harrison, A. Wyllie, 1997, Gut.

N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.

C. Smith, D. Harrison, A. Wyllie, 1998, British Journal of Cancer.

Evaluation of glutathione S-transferase Pi in non-invasive ductal carcinoma of breast.

D. Harrison, C. Bellamy, Coc Bellamy, 1994, British Journal of Cancer.

Genetic interactions between the Wilms' tumor 1 gene and the p53 gene.

D. Harrison, A. Clarke, L. Spraggon, 2002, Cancer research.

Modulation of glutathione S-transferases and glutathione peroxidase by the anticarcinogen butylated hydroxyanisole in murine extrahepatic organs.

D. Harrison, J. Hayes, L. McLellan, 1992, Carcinogenesis.

Preferential over-expression of the class alpha rat Ya2 glutathione S-transferase subunit in livers bearing aflatoxin-induced pre-neoplastic nodules. Comparison of the primary structures of Ya1 and Ya2 with cloned class alpha glutathione S-transferase cDNA sequences.

D. Harrison, J. Hayes, G. Neal, 1990, Biochemical Journal.

Glutathione S-transferases in alcoholic liver disease.

P. Hayes, D. Harrison, J. Hayes, 1990, Gut.

Cytosolic and microsomal glutathione S-transferase isoenzymes in normal human liver and intestinal epithelium.

P. Hayes, D. Harrison, J. Hayes, 1989, Gut.

Glutathione S-transferases in human liver cancer.

P. Hayes, D. Harrison, J. Hayes, 1991, Gut.

Glutathione S-transferase isoenzymes in human renal carcinoma demonstrated by immunohistochemistry.

D. Harrison, J. Hayes, R. Kharbanda, 1989, Carcinogenesis.

Cell death in health and disease: the biology and regulation of apoptosis.

D. Harrison, A. Wyllie, R. Malcomson, 1995, Seminars in cancer biology.

Distribution of glutathione S-transferase isoenzymes in primary epithelial tumors of the ovary

D. Harrison, M. Rahilly, A. A. Al Nafussi, 1991, International Journal of Gynecologic Cancer.

Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells.

W. MacNee, I. Rahman, C. Smith, 1996, Biochemical and biophysical research communications.

Glutathione and p53 independently mediate responses against oxidative stress in ES cells.

I. Rahman, D. Harrison, A. Clarke, 2002, Free radical biology & medicine.

IMMUNOLOCALISATION OF GLUTATHIONE S-TRANSFERASE IN HUMAN RENAL AND LIVER DISEASE

P. Hayes, D. Harrison, 1990 .

Utilizing mRNA extracted from small, archival formalin-fixed paraffin-embedded prostate samples for translational research: assessment of the effect of increasing sample age and storage temperature

D. Harrison, G. Stewart, F. Rae, 2011, International Urology and Nephrology.

Evaluation ofglutathione S-transferase Piinnon-invasive ductal carcinoma ofbreast

D. Harrison, C. Bellamy, 1994 .

Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer

C. Smith, D. Harrison, A. Wyllie, 1999, British Journal of Cancer.

Heterogeneous expression and polymorphic genotype of glutathione S-transferases in human lung.

C. Smith, D. Lamb, D. Harrison, 1994, Thorax.

Apoptosis: molecular aspects and pathological perspective

D. Harrison, M. Arends, 1994 .

Glutathione s‐transferase detoxication enzymes in cervical neoplasia

D. Harrison, P. Carder, A. al-Nafussi, 1990, The Journal of pathology.

Apoptosis in vivo and in vitro: conflict or complementarity?

D. Harrison, A. Clarke, N. Sphyris, 1996, Molecular medicine today.

Association between the CYP1A1 gene polymorphism and susceptibility to emphysema and lung cancer

C. Smith, D. Lamb, D. Harrison, 1995, Clinical molecular pathology.

Autoantibodies to hepatic microsomal carboxylesterase in halothane hepatitis

D. Harrison, C. Wolf, D. Tew, 1993, The Lancet.

Integrin characterization in pulmonary bronchioles.

D. Harrison, R. Blundell, 2005, Experimental and molecular pathology.

Molecular genetics of the human cytochrome P450-dependent monooxygenases.

C. Smith, D. Harrison, C. Wolf, 1992, The Tohoku journal of experimental medicine.

Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model

D. Cameron, D. Harrison, R. L. Hayward, 2022, Exploration of targeted anti-tumor therapy.

A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome.

A. Brookes, D. Porteous, K. Miyagawa, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Lymphocytes from orally tolerized mice display enhanced susceptibility to death by apoptosis when cultured in the absence of antigen in vitro.

D. Harrison, S. Howie, E. Worthey, 1996, The American journal of pathology.

Anti-emetic efficacy of dexamtheasone in combination for out-patients receiving cytotoxic chemotherapy

D. Harrison, R. Leonard, S. Allan, 2004, Cancer Chemotherapy and Pharmacology.

UV but not gamma-irradiation induces specific transcriptional activity of p53 in primary hepatocytes.

D. Harrison, A. Wyllie, S. Prost, 1997, The Journal of pathology.

UV but not γ‐irradiation induces specific transcriptional activity of p53 in primary hepatocytes

D. Harrison, A. Wyllie, S. Prost, 1997 .

Adenovirus-mediated Cre deletion of floxed sequences in primary mouse cells is an efficient alternative for studies of gene deletion.

D. Harrison, S. Prost, S. Sheahan, 2001, Nucleic acids research.

Edinburgh Research Explorer TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21(Cip1) or Rb status

D. Harrison, S. Prost, S. Sheahan, 2008 .

Genetic Interactions between the Wilms ’ Tumor 1 Gene and the p 53 Gene 1

D. Harrison, A. Clarke, L. Spraggon, 2002 .

Life and death in the genesis of the tumour cell.

D. Harrison, 1998, Toxicology Letters.

Growth factor attenuation of IFNγ‐mediated hepatocyte apoptosis requires p21waf−1

D. Harrison, C. McCullough, B. J. Tura, 2006, International journal of experimental pathology.

Induction of gamma-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells.

W. MacNee, I. Rahman, C. Smith, 1996, FEBS letters.

Cell death in the diseased glomerulus

D. Harrison, D. Harrison, 1988, Histopathology.

Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.

D. Harrison, J. Hayes, G. Neal, 1998, The Biochemical journal.

Apoptosis: a distinctive form of cell death

D. Harrison, L. Jordan, 2000 .

Autoantibodies to neutrophil cytoplasmic antigens in systemic vasculitis have the same target specificity

D. Harrison, R. Kharbanda, D. Harrison, 1989, The Journal of pathology.

Evidence of hydrogen ion secretion from the human gall bladder in vitro.

P. Hayes, D. Harrison, J. Plevris, 1992, Gut.

Identification of novel alleles at a polymorphic microsatellite repeat region in the human NRAMP1 gene promoter: analysis of allele frequencies in primary biliary cirrhosis

D. Harrison, S. Howie, M. Dollinger, 2000, Journal of medical genetics.

Podocyte injury elicits loss and recovery of cellular forces

D. Harrison, P. Reynolds, M. Gather, 2018, Science Advances.

YAP Translocation Precedes Cytoskeletal Rearrangement in Podocyte Stress Response: A Podometric Investigation of Diabetic Nephropathy

P. Caie, D. Harrison, I. Um, 2021, Frontiers in Physiology.

Edinburgh Research Explorer Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anticancer therapy

Hilal S. Khalil, J. Bown, D. Harrison, 2018 .

Transjugular intrahepatic portosystemic stent-shunt (TIPSS) occlusion and the role of biliary venous fistulae.

P. Hayes, R. Jalan, D. Harrison, 1996, Journal of hepatology.

Bile duct cells in primary biliary cirrhosis are 'primed' for apoptosis

D. Harrison, S. Howie, M. Dollinger, 1998, European journal of gastroenterology & hepatology.

γ-Glutamylcysteine synthetase induction by cigarette smoke exposure in alveolar epithelial cells

W. MacNee, I. Rahman, D. Harrison, 1994 .

Explorer Allosteric Modulation of Beta 1 Integrin Function Induces Lung Tissue Repair

D. Harrison, Fiona Rossi, Beth Harrison, 2017 .

Allosteric Modulation of Beta1 Integrin Function Induces Lung Tissue Repair

D. Harrison, Fiona Rossi, S. McIntyre, 2012, Advances in Pharmacological Sciences.

Allosteric Modulation of Beta 1 Integrin Function Induces Lung Tissue Repair Rehab

D. Harrison, Fiona Rossi, Beth Harrison, 2012 .

Improved Retention of Zymogen Granules in Cultured Murine Pancreatic Acinar Cells and Induction of Acinar-Ductal Transdifferentiation In Vitro

D. Harrison, C. Logsdon, N. Sphyris, 2005, Pancreas.

p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells

D. Harrison, N. Sphyris, 2005, Oncogene.

The Importance of Growth Factors and Steroid Hormones in Ovarian Cancer

D. Harrison, S. Langdon, D. Faratian, 2009, Oncology Research and Treatment.

Idiopathic portal hypertension associated with cytotoxic drugs.

D. Harrison, P. Shepherd, 1990, Journal of clinical pathology.

Bone marrow stem cells contribute to alcohol liver fibrosis in humans.

P. Hayes, W. Bickmore, S. Boyle, 2010, Stem cells and development.

To live or die--a cell's choice.

D. Harrison, M. Link, 2001, Essays in biochemistry.

University of Dundee Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf 2 ( NF-E 2 p 45-Related Factor 2 )

D. Harrison, J. Hayes, A. Dinkova-Kostova, 2018 .

Effect of glandular metastases on overall survival of patients with metastatic clear cell renal cell carcinoma in the antiangiogenic therapy era.

D. Harrison, N. Salem, N. Vasudev, 2016, Urologic oncology.

Apoptotic cell death during renal transplant rejection.

D. Harrison, D. Gouldesbrough, 1990, Journal of clinical pathology.

Polymorphisms of the gene for microsomal epoxide hydrolase and susceptibility to alcoholic liver disease and hepatocellular carcinoma in a Caucasian population.

C. Smith, D. Harrison, A. Bathgate, 2000, Toxicology letters.

c‐Myc partially mediates IFNγ‐induced apoptosis in the primary hepatocyte

D. Harrison, C. McCullough, B. J. Tura, 2007 .

Gene transfer to adult human lung tissue ex vivo

D. Harrison, S. McBride, D. Rannie, 2000, Gene Therapy.

Apoptosis and carcinogenesis.

D. Harrison, A. Wyllie, S. Corbet, 1999, British journal of cancer.

Establishing a molecular taxonomy for epithelial ovarian cancer (EOC) from 363 formalin-fixed paraffin embedded (FFPE) specimens.

T. Davison, D. Harrison, C. Gourley, 2011, Journal of Clinical Oncology.

Sequence of melanocyte migration into human scar tissue

A. Busuttil, D. Harrison, J. Dressler, 2001, International Journal of Legal Medicine.

Novel histopathologic findings in a surviving case of hemolytic uremic syndrome after bone marrow transplantation.

D. Harrison, M. Arends, 1989, Human pathology.

The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial

R. Plummer, D. Harrison, G. Bond, 2021, Clinical Cancer Research.

Spatial Analysis of NQO1 in Non-Small Cell Lung Cancer Shows Its Expression Is Independent of NRF1 and NRF2 in the Tumor Microenvironment

D. Harrison, I. Um, M. Elshani, 2022, Biomolecules.

The effect of inhibition of glutathione S‐transferase P on the growth of the jurkat human T cell line

D. Harrison, F. McCaughan, A. L. Brown, 1994, The Journal of pathology.

An unusual interpodocyte cell junction and its appearance in a transplant graft kidney.

D. Harrison, D. Jenkins, J. Dick, 1988, Journal of clinical pathology.

Glutathione S-transferase expression in the human testis and testicular germ cell neoplasia.

D. Harrison, H. Klys, D. Whillis, 1992, British Journal of Cancer.

p73α is a candidate effector in the p53 independent apoptosis pathway of cisplatin damaged primary murine colonocytes

A. Oniscu, D. Harrison, S. Bader, 2004, Journal of Clinical Pathology.

Thymocyte apoptosis induced by p53-dependent and independent pathways

C. Purdie, D. Harrison, A. Wyllie, 1993, Nature.

Identifying prognostic structural features in tissue sections of colon cancer patients using point pattern analysis

David J Harrison, Ben C Stevenson, Anne Savage, 2018, Statistics in medicine.

Percutaneous renal biopsy specimens in stone formers.

D. Harrison, D. Tolley, J. Inglis, 1988, Journal of clinical pathology.

Intrahepatic proliferation of ‘naive’ and ‘memory’ T cells during liver allograft rejection: primary immune response within the allograft

P. Hayes, D. Harrison, S. Howie, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antibodies to neutrophil cytoplasmic antigens: serologic marker for Sweet's syndrome.

D. Harrison, J. Hunter, D. Kemmett, 1991, Journal of the American Academy of Dermatology.

Tissue-Specific Immunopathology in Fatal COVID-19

Colin Smith, J. Baillie, K. Dhaliwal, 2020, American journal of respiratory and critical care medicine.

Functional analysis of mouse hepatocytes differing in DNA content: Volume, receptor expression, and effect of IFNγ

D. Harrison, L. Sharp, P. Bush, 2002, Journal of cellular physiology.

Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis.

D. Harrison, A. Clarke, H. Wallace, 1996, Oncogene.

Spatial immune profiling of the colorectal tumor microenvironment predicts good outcome in stage II patients

H. Ueno, P. Caie, D. Harrison, 2020, npj Digital Medicine.

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.

Colm E. Nestor, J. Dixon, R. Meehan, 2012, Genome research.

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen

Azusa Yamaguchi, Galina Lebedeva, Simon P. Langdon, 2012, BMC Systems Biology.

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031

D. Harrison, P. Mullen, I. Um, 2019, Scientific Reports.

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

W. Bickmore, E. C. Schirmer, S. Boyle, 2013, Genome Biology.

Sprouty 2 Is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy

D. Harrison, P. Mullen, S. Langdon, 2011, PloS one.

Phosphoprotein pathway profiling of ovarian carcinoma for the identification of potential new targets for therapy.

D. Harrison, P. Mullen, S. Langdon, 2011, European journal of cancer.

Cancer systems biology.

David J Harrison, V. Smith, J. Bown, 2016, Methods in molecular biology.

Dysregulated expression of β-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice

O. Sansom, D. Harrison, A. Wyllie, 1999, Oncogene.

Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells.

S. Knuutila, P. Peltomäki, D. Harrison, 2008, DNA repair.

High-frequency developmental abnormalities in p53-deficient mice

M. Kaufman, D. Harrison, A. Clarke, 1995, Current Biology.

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system

V. Anne Smith, Simon P. Langdon, David J. Harrison, 2015 .

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

B. Ramsahoye, R. Meehan, D. Harrison, 2011, Proceedings of the National Academy of Sciences.

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest

D. Harrison, S. Prost, C. Bellamy, 2007, BMC Cancer.

Edinburgh Research Explorer 5-hydroxymethylcytosine profiling as an indicator of cellular state

J. Thomson, R. Meehan, D. Harrison, 2013 .

Forensic DNA Profiling in Cases Involving Children

D. Harrison, A. Graham, 2009 .

Alteration in mRNA levels of Fas splice variants in hepatitis C‐infected liver

D. Harrison, R. Malcomson, D. Ferenbach, 1997, The Journal of pathology.

Apoptosis: an overview of the process and its relevance in disease.

D. Harrison, A. Wyllie, S. Webb, 1997, Advances in pharmacology.

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes

J. Mason, D. Harrison, A. Clarke, 2002, Oncogene.

Explorer Targeting of Rac GTPases blocks the spread of intact human breast cancer

R. Meehan, D. Harrison, J. Dixon, 2017 .

Targeting of Rac GTPases blocks the spread of intact human breast cancer

R. Meehan, D. Harrison, J. Dixon, 2012, Oncotarget.

Epigenetic sampling effects: nephrectomy modifies the clear cell renal cell cancer methylome

D. Deforce, D. Harrison, Christophe Van Neste, 2017, Cellular Oncology.

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

B. Ramsahoye, N. Gilbert, D. Harrison, 2012, Nucleic acids research.

The effect of IFNγ on the hepatocyte: cell cycle and apoptosis

D. Harrison, Benjamin J. Tura, Kerry E. Bunyan, 2001 .

Counting alleles to predict recurrence of early-stage colorectal cancers

S. Goodman, M. Choti, E. Montgomery, 2002, The Lancet.

content of human genes Tissue type is a major modifier of the 5-hydroxymethylcytosine Material Supplemental

J. Dixon, R. Meehan, J. Reddington, 2012 .

HER2 expression in ovarian carcinoma: caution and complexity in biomarker analysis

D. Harrison, S. Langdon, I. Um, 2012, Journal of Clinical Pathology.

The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.

D. Harrison, M. Arends, S. Plowman, 2006, Experimental cell research.

CAN-10-0911 Cancer esearch or and Stem Cell Biology sine Phosphorylation Profiling Reveals the Signaling R work Characteristics of Basal Breast Cancer Cells

David R. Croucher, D. Croucher, S. O'toole, 2010 .

Cancer esearch or and Stem Cell Biology sine Phosphorylation Profiling Reveals the Signaling R work Characteristics of Basal Breast Cancer Cells

David R. Croucher, D. Croucher, S. O'toole, 2010 .

What can molecular pathology contribute to the management of renal cell carcinoma?

D. Harrison, D. Faratian, T. Powles, 2011, Nature Reviews Urology.

TMA Navigator: network inference, patient stratification and survival analysis with tissue microarray data

David J. Harrison, Alexander L. R. Lubbock, Ian M. Overton, 2013, Nucleic Acids Res..

Use of microarray analysis to investigate EMT gene signatures.

D. Harrison, A. Larionov, A. Sims, 2013, Methods in molecular biology.

Two possible mechanisms of epithelial to mesenchymal transition in invasive ductal breast cancer

D. Harrison, D. Faratian, E. Katz, 2011, Clinical & Experimental Metastasis.

An In Vitro Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer

R. Meehan, D. Harrison, A. Sims, 2011, PloS one.

WWOX gene expression abolishes ovarian cancer tumorigenicity in vivo and decreases attachment to fibronectin via integrin alpha3.

A. Paige, H. Gabra, C. Ward, 2009, Cancer research.

Could molecular pathology testing in lung cancer be more cost-effective?

A. Oniscu, D. Harrison, W. Wallace, 2016, Journal of Clinical Pathology.

Independent regulation of P53 stabilisation and activation after Rb deletion in primary epithelial cells.

D. Harrison, S. Prost, C. Bellamy, 2010, International journal of oncology.

p53, mutation frequency and apoptosis in the murine small intestine

D. Winton, D. Harrison, A. Clarke, 1997, Oncogene.

Additive effect of p53, p21 and Rb deletion in triple knockout primary hepatocytes

David J Harrison, D. Harrison, S. Prost, 2004, Oncogene.

Chapter 4 Acquired and Intrinsic Resistance to Colorectal Cancer Treatment

D. Harrison, Romina Briffa, G. Grech, 2018 .

Acquired and intrinsic resistance to colorectal cancer treatment

D. Harrison, Romina Briffa, G. Grech, 2017 .

The Effect of VEGF-Targeted Therapy on Biomarker Expression in Sequential Tissue from Patients with Metastatic Clear Cell Renal Cancer

D. Berney, Yong-jie Lu, M. Gerlinger, 2013, Clinical Cancer Research.

Tissue Proteomic Analysis Identifies Mechanisms and Stages of Immunopathology in Fatal COVID-19

J. Baillie, A. Akram, K. Dhaliwal, 2021, American journal of respiratory cell and molecular biology.

Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases.

D Faratian, D. Harrison, S. Langdon, 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

Prognostic relevance of DNA copy number changes in colorectal cancer

S. Leung, S. Yuen, K. Ichimura, 2010, The Journal of pathology.

Pertuzumab for the treatment of ovarian cancer

D. Harrison, P. Mullen, S. Langdon, 2010, Expert opinion on biological therapy.

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence

David J. Harrison, Mark Gustavson, D. Harrison, 2011, Journal of visualized experiments : JoVE.

While K-ras Is Essential for MouseDevelopment, Expression of the K-ras 4A Splice VariantIsDispensable

D. Harrison, M. Arends, D. Melton, 2003, Molecular and Cellular Biology.

p53 deficiency in liver reduces local control of survival and proliferation, but does not affect apoptosis after DNA damage

D. Harrison, A. Wyllie, A. Clarke, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

WHO/ISUP classification, grading and pathological staging of renal cell carcinoma: standards and controversies

D. Harrison, A. Warren, 2018, World Journal of Urology.

Potential of Hematopoietic Stem Cell Therapy in Hepatology: A Critical Review

D. Harrison, P. Newsome, J. Plevris, 2004, Stem cells.

A simplified assay for the arylamine N-acetyltransferase 2 polymorphism validated by phenotyping with isoniazid.

C. Smith, D. Harrison, C. Wolf, 1997, Journal of medical genetics.

A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells

Hilal S. Khalil, J. Bown, D. Harrison, 2016, Oncotarget.

Characterising the tumour morphological response to therapeutic intervention: an ex vivo model

Ruth E. Falconer, David J. Harrison, Elad Katz, 2012, Disease Models & Mechanisms.

A Phase Ib Open-Label, Dose-Escalation Study of NUC-1031 in Combination with Carboplatin for Recurrent Ovarian Cancer

H. Gabra, D. Harrison, S. Nicum, 2021, Clinical Cancer Research.

The effect of the somatostatin analogue SMS 201-995 on experimental pancreatic carcinogenesis in the Syrian golden hamster.

G. Haddock, D. Harrison, D. Carter, 1991, Carcinogenesis.

K-ras 4A and 4B are co-expressed widely in human tissues, and their ratio is altered in sporadic colorectal cancer.

D. Harrison, M. Arends, S. Plowman, 2006, Journal of experimental & clinical cancer research : CR.

A functional, discontinuous HIV‐1 gp120 C3/C4 domain‐derived, branched, synthetic peptide that binds to CD4 and inhibits MIP‐1α chemokine binding

D. Harrison, S. Howie, D. Innes, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Explorer Clinical significance of intrahepatic hepatitis C virus levels in patients with chronic HCV infection

P. Simmonds, P. Hayes, D. Harrison, 2017 .

Association between chronic hepatitis C infection and hepatocellular carcinoma in a Scottish population.

P. Simmonds, P. Hayes, O. Garden, 1997, Gut.

Association between chronic hepatitis C infection and hepatocellular carcinoma in a Scottish population Methods Patients

P. Simmonds, P. Hayes, D. Harrison, 2022 .

Stem Cell Factor Attenuates Liver Damage in a Murine Model of Acetaminophen-Induced Hepatic Injury

D. Harrison, S. Kunkel, C. Hogaboam, 2003, Laboratory Investigation.

Differential Expression of Prognostic Proteomic Markers in Primary Tumour, Venous Tumour Thrombus and Metastatic Renal Cell Cancer Tissue and Correlation with Patient Outcome

D. Harrison, G. Stewart, F. O’Mahony, 2013, PloS one.

Regulation of cytochrome P450 gene expression in human colon and breast tumour xenografts.

C. Wolf, D. Harrison, G. Smith, 1993, British Journal of Cancer.

Apoptosis and DNA Methylation

Monika J. Madej, R. Meehan, J. Reddington, 2011, Cancers.

Characterisation of Lectin Binding Patterns of Mouse Bronchiolar and Rat Alveolar Epithelial Cells in Culture

D. Harrison, Z. Kováčiková, Tim M. Smith, 2004, The Histochemical Journal.

CIRCULATING ANTI-NEUTROPHIL ANTIBODIES IN SYSTEMIC VASCULITIS

D. Harrison, C. Wathen, 1987, The Lancet.

Mitochondrial D-loop mutations and deletion profiles of cancerous and noncancerous liver tissue in hepatitis B virus-infected liver

D. Harrison, P. Lai, J. Ross, 2005, British Journal of Cancer.

Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema

D. Harrison, Christopher A. Smith, 1997, The Lancet.

Liver death and regeneration in paracetamol toxicity

D. Harrison, K. Simpson, A. McGregor, 2003, Human & experimental toxicology.

Automated Detection and Classification of Desmoplastic Reaction at the Colorectal Tumour Front Using Deep Learning

H. Ueno, P. Caie, D. Harrison, 2021, Cancers.

Dynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer

Liang Liang, David J Harrison, D. Cameron, 2010, Breast Cancer Research.

The cost of treating skeletal-related events in patients with prostate cancer.

David J Harrison, D. Harrison, M. Lage, 2008, The American journal of managed care.

Gonadotropin-releasing hormone receptor levels and cell context affect tumor cell responses to agonist in vitro and in vivo.

D. Harrison, P. Mullen, S. Langdon, 2008, Cancer research.

Distribution of glutathione S-transferase isoenzymes in human ovary.

D. Harrison, P. Carder, M. Rahilly, 1991, Journal of reproduction and fertility.

Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury.

D. Harrison, J. Hayes, L. McLellan, 1989, Journal of clinical pathology.

MBD 4 Interacts with and Recruits USP 7 to heterochromatic foci †

R. Meehan, D. Harrison, Huan Meng, 2014 .

Beta1 integrin in tissue remodelling and repair: from phenomena to concepts.

D. Harrison, R. Al-Jamal, 2008, Pharmacology & therapeutics.

Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models

C. Ward, A. Turnbull, D. Harrison, 2016, British Journal of Cancer.

Investigation of the role of ROS modulation in the antitumour effect of a novel breast cancer drug

C. Ward, D. Harrison, P. Mullen, 2014 .

SV40 Tag DNA sequences, present in a small proportion of human hepatocellular carcinomas, are associated with reduced survival

D. Harrison, D. Brewster, N. Wong, 2003, Journal of clinical pathology.

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017, Oncotarget.

Explorer Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017 .

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

P. Lambin, L. Dubois, C. Supuran, 2015, Oncotarget.

Translational research will fail without surgical leadership: SCOTRRCC a successful surgeon-led Nationwide translational research infrastructure in renal cancer.

D. Harrison, D. McLaren, L. McLornan, 2015, The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.

The use of reverse phase protein arrays (RPPA) to explore protein expression variation within individual renal cell cancers.

I. Overton, D. Harrison, P. Mullen, 2013, Journal of visualized experiments : JoVE.

Renal biopsy and antineutrophil antibodies in the diagnosis and assessment of Wegener's granuloma.

D. Harrison, C. Wathen, R. Simpson, 1988, British journal of diseases of the chest.

Counting apoptosis—why and how?

D. Harrison, 1996, Clinical molecular pathology.

Changes in the expression of p21, p27 and p53 following beta-1 integrin blocking in murine Clara cells cultures

D. Harrison, R. Blundell, 2006 .

A Comparison of Methods for Studying the Tumor Microenvironment's Spatial Heterogeneity in Digital Pathology Specimens

H. Ueno, P. Caie, D. Harrison, 2021, Journal of pathology informatics.

Assessment of Immunological Features in Muscle-Invasive Bladder Cancer Prognosis Using Ensemble Learning

P. Caie, D. Harrison, G. Schmidt, 2021, Cancers.

Dynamic Reprogramming of Signalling Networks - A New Challenge in Cancer Therapy

J. Bown, D. Harrison, S. Langdon, 2014 .

Feedforward and feedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer.

J. Bown, D. Harrison, S. Langdon, 2013, Cellular signalling.

Defining the molecular response to trastuzumab, pertuzumab and combination therapy in ovarian cancer

D. Harrison, S. Langdon, I. Um, 2012, British Journal of Cancer.

Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

D. Harrison, P. Mullen, S. Langdon, 2011, Clinical Cancer Research.

Modulation of HER3 Is a Marker of Dynamic Cell Signaling in Ovarian Cancer: Implications for Pertuzumab Sensitivity

D. Harrison, P. Mullen, S. Langdon, 2009, Molecular Cancer Research.

Glutathione S-transferase localization in aflatoxin B1-treated rat livers.

D. Harrison, J. Hayes, G. Neal, 1990, Carcinogenesis.

Chemical analysis of multicellular tumour spheroids.

C. Campbell, D. Harrison, L. E. Jamieson, 2015, The Analyst.

Role of post-translational regulation pten activity in cancer cell addiction to heterozygous mutations

Hilal S. Khalil, J. Bown, D. Harrison, 2013 .

Pathways of T cell mediated cytotoxicity in hepatic allograft rejection

P. Hayes, D. Harrison, J. Plevris, 1998 .

Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia

A. Oniscu, D. Harrison, S. Bader, 2004, The Journal of pathology.

Explorer Deficiency of G 1 regulators P 53 , P 21 Cip 1 and / or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest

D. Harrison, S. Prost, C. Bellamy, 2017 .

Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396)

D. Harrison, S. Fleming, K. Wood, 2008, Transgenic Research.

The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle.

M. Salto‐Tellez, J. Ross, W. Yeo, 2008, Journal of hepatology.

Single strand DNA breaks in mitogen stimulated T lymphocytes are religated by a mechanism independent of accessory cells.

D. Harrison, A. Wyllie, A. Crowe, 1989, Clinical and experimental immunology.

Polymorphism in gene for microsomal epoxide hydrolase and lung disease

C. Smith, D. Harrison, 1997, The Lancet.

Context-based interpolation of coarse deep learning prediction maps for the segmentation of fine structures in immunofluorescence images

Nicolas Brieu, Günter Schmidt, David J. Harrison, 2018, Medical Imaging.

Primary culture of bovine gall bladder epithelial cells.

P. Hayes, D. Harrison, J. Plevris, 1993, Gut.

Validation of a Molecular and Pathological Model for Five-Year Mortality Risk in Patients with Early Stage Lung Adenocarcinoma

I. Wistuba, R. Bueno, A. Gutin, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Synthetic peptides representing discontinuous CD4 binding epitopes of HIV‐1 gp120 that induce T cell apoptosis and block cell death induced by gp120

D. Harrison, S. Howie, Nicola Martin, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models

V. Smith, D. Harrison, S. Langdon, 2016, BMC Cancer.

Chemotherapy-induced dynamic gene expression changes in vivo are prognostic in ovarian cancer

V. Smith, D. Harrison, S. Langdon, 2014, British Journal of Cancer.

266 Mobilization of pluripotent haematopoietic stem cells occurs in alcoholic hepatitis and is associated with an improved clinical outcome

P. Hayes, D. Harrison, P. Newsome, 2003 .

Novel Monte Carlo approach quantifies data assemblage utility and reveals power of integrating molecular and clinical information for cancer prognosis

V. Smith, D. Harrison, S. Langdon, 2015, Scientific Reports.

Human tissue in systems medicine

Peter D Caie, David J Harrison, Klaas Schuur, 2013, The FEBS journal.

Cancer Therapy: Preclinical Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

D. Harrison, P. Mullen, S. Langdon, 2011 .

Hoechst Is All You Need: Lymphocyte Classification with Deep Learning pdf

David J Harrison, Jessica Cooper, Ognjen Arandjelovi'c, 2021, ArXiv.

Renal cholesterol granulomas: identification and morphological pattern of development

D. Harrison, 1986, Histopathology.

RAMPART: A model for a regulatory-ready academic-led phase III trial in the adjuvant renal cell carcinoma setting.

E. Frangou, M. Stockler, T. Choueiri, 2021, Contemporary clinical trials.

Increase in p21 expression independent of the p53 pathway in bleomycin-induced lung fibrosis.

N. Kaminski, D. Harrison, R. Blundell, 2004, Experimental and molecular pathology.

Attaching and Effacing Escherichia coli Downregulate DNA Mismatch Repair Protein In Vitro and Are Associated with Colorectal Adenocarcinomas in Humans

D. Harrison, M. Donnenberg, S. Bader, 2009, PloS one.

Antibodies to neutrophil cytoplasmic antigens in Wegener's granulomatosis and other conditions.

D. Harrison, G. Nimmo, V. E. Abernethy, 1989, Thorax.

Next-Generation Pathology.

Peter D Caie, David J Harrison, P. Caie, 2016, Methods in molecular biology.

Hyperoxia inhibits alveolar epithelial repair by inhibiting the transdifferentiation of alveolar epithelial type II cells into type I cells

D. Harrison, S. Mckechnie, M. Mcelroy, 2008, Critical Care.

Evaluation of the dual mTOR/PI3K inhibitors Gedatolisib (PF-05212384) and PF-04691502 against ovarian cancer xenograft models

D. Harrison, S. Langdon, I. Um, 2019, Scientific Reports.

Cyclin D1 and p21 in ulcerative colitis-related inflammation and epithelial neoplasia: a study of aberrant expression and underlying mechanisms.

I. Brock, D. Harrison, J. Royds, 2003, Human pathology.

A functional, discontinuous HIV-1 gp120 C3/C4 domain-derived, branched, synthetic peptide that binds to CD4 and inhibits MIP-1alpha chemokine binding.

D. Harrison, S. Howie, D. Innes, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased STAT1 Signaling in Endocrine-Resistant Breast Cancer

D. Harrison, Rui Huang, S. Langdon, 2014, PloS one.

Increased STAT 1 Signaling in Endocrine-Resistant Breast Cancer

D. Harrison, Rui Huang, S. Langdon, 2014 .

Microarray analysis of gene expression of mouse hepatocytes of different ploidy

D. Harrison, G. Betton, S. Prost, 2007, Mammalian Genome.

A clear cell tumour of the parotid

D. Harrison, K. Mclaren, W. Tennant, 1987, The Journal of Laryngology & Otology.

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

D. Harrison, J. Hayes, A. Dinkova-Kostova, 2017, Cellular and molecular gastroenterology and hepatology.

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications

R. Owens, M. McPherson, D. Harrison, 2014, Protein engineering, design & selection : PEDS.

Apoptosis in carcinogenesis: the role of p53.

M. Greaves, D. Harrison, A. Wyllie, 1994, Cold Spring Harbor symposia on quantitative biology.

In vivo and In vitro Context Affect Tumor Cell Responses to Agonist Gonadotropin-Releasing Hormone Receptor Levels and Cell

D. Harrison, P. Mullen, S. Langdon, 2008 .

Risk score predicts high‐grade prostate cancer in DNA‐methylation positive, histopathologically negative biopsies

A. Partin, J. Epstein, L. van Neste, 2016, The Prostate.

Unusual structures inherent in point pattern data predict colon cancer patient survival

Charlotte M. Jones-Todd, J. Illian, P. Caie, 2017, 1705.05938.

GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines

David J Harrison, Colette Meyer, Kevin Morgan, 2011, BMC Cancer.

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema.

D. Harrison, S. Shapiro, Chris Armit, 2007 .

repair in animal model of emphysema.

D. Harrison, S. Shapiro, Chris Armit, 2007 .

Leukaemia cell markers.

D. Harrison, A. Dewar, G. Stockdill, 2009, Scandinavian Journal of Haematology.

The molecular biology of renal cancer: another piece of the puzzle.

D. Berney, D. Harrison, T. Powles, 2014, European urology.

Interim pharmacokinetic (PK) and pharmacodynamic (PD) data from the first-in-human study of NUC-3373, a pyrimidine nucleotide analogue, in patients with advanced solid tumors

D. Harrison, J. Moschandreas, S. Blagden, 2017 .

Somatic cancer genetics in the UK: real-world data from phase I of the Cancer Research UK Stratified Medicine Programme

A. Nicholson, J. Brenton, K. Blyth, 2018, ESMO Open.

Novel Internationally Verified Method Reports Desmoplastic Reaction as the Most Significant Prognostic Feature For Disease-specific Survival in Stage II Colorectal Cancer

H. Ueno, P. Caie, D. Harrison, 2019, The American journal of surgical pathology.

The Use of Automated Quantitative Analysis to Evaluate Epithelial-to-Mesenchymal Transition Associated Proteins in Clear Cell Renal Cell Carcinoma

M. Theodoulou, D. Harrison, D. Faratian, 2012, PloS one.

Explorer Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma

I. Wistuba, R. Bueno, A. Gutin, 2017 .

Liver biopsy findings in patients with alcoholic liver disease complicated by chronic hepatitis C virus infection.

P. Simmonds, P. Hayes, D. Harrison, 1995, European journal of gastroenterology & hepatology.

The effect of IFNgamma on the hepatocyte: cell cycle and apoptosis.

D. Harrison, B. Tura, K. Bunyan, 2001, International journal of experimental pathology.

TNF-α induced DNA damage in primary murine hepatocytes

J. Ross, D. Harrison, S. Prost, 2003 .

Predicting response to the anti-estrogen fulvestrant in recurrent ovarian cancer.

D. Harrison, S. Langdon, I. Um, 2013, Gynecologic oncology.

Cellular response to cancer chemopreventive agents: contribution of the antioxidant responsive element to the adaptive response to oxidative and chemical stress.

D. Harrison, J. Hayes, E. Ellis, 1999, Biochemical Society symposium.

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

F. Pontén, M. Uhlén, D. Djureinovic, 2017, BMC Cancer.

Structure, Properties, and Engineering of the Major Zinc Binding Site on Human Albumin*

P. Sadler, D. Harrison, D. Sleep, 2009, The Journal of Biological Chemistry.

The Efficacy of Sunitinib Treatment of Renal Cancer Cells Is Associated with the Protein PHAX In Vitro

A. Reverter, A. Turnbull, D. Harrison, 2020, Biology.

Computerized Image Analysis of Tumor Cell Nuclear Morphology Can Improve Patient Selection for Clinical Trials in Localized Clear Cell Renal Cell Carcinoma

P. Tan, P. Caie, D. Harrison, 2020, Journal of pathology informatics.

Acetaminophen-induced fulminant hepatic failure results in an SDF-1 mediated 'all or nothing' haematopoietic stem cell response.

P. Hayes, C. Payne, D. Harrison, 2005 .

Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer

D. Harrison, A. Wyllie, Susan White, 2000, The Journal of pathology.

Spatial immune profiling of the colorectal tumor microenvironment predicts good outcome in stage II patients.

H. Ueno, P. Caie, D. Harrison, 2020, npj Digital Medicine.

Update of the International Banff Schema for liver allograft rejection: Working recommendations for the histopathologic staging and reporting of chronic rejection

R. Wiesner, A. Dhillon, F. Reinholt, 2000, Hepatology.

Apoptosis and carcinogenesis.

S. Lyons, D. Harrison, A. Wyllie, 1999, British medical bulletin.

Genetic and epigenetic analyses of MBD3 in colon and lung cancer

D. Harrison, S. Bader, S. Bader, 2004, British Journal of Cancer.

Serum hyaluronan ‐ a non‐invasive test for diagnosing liver cirrhosis

P. Hayes, D. Harrison, J. Plevris, 2000, European journal of gastroenterology & hepatology.

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

D. Harrison, P. Butler, R. Ashley, 1999, Diabetes.

CFTR gene transfer to lung epithelium--on the trail of a target cell.

S. O'Dea, D. Harrison, 2002, Current gene therapy.

A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma

F. Pontén, M. Uhlén, D. Djureinovic, 2017, BMC Cancer.

Animal models amd the molecular pathology of Cancer

D. Harrison, E. Lovejoy, A. Clarke, 1997, The Journal of pathology.

Systems biology reveals new strategies for personalizing cancer medicine and confirms the role of PTEN in resistance to trastuzumab.

Stuart L. Moodie, I. Goryanin, A. Sorokin, 2009, Cancer research.

Hematopoietic stem cell trafficking in liver injury

D. Harrison, P. Newsome, E. Dalakas, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

Robert S. Illingworth, A. Bird, D. Turner, 2010, PLoS genetics.

Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies

D. Harrison, P. Mullen, S. Langdon, 2011, Clinical Cancer Research.

The Effect of VEGF-Targeted Therapy on Biomarker Expression in Sequential Tissue from Patients with Metastatic Clear Cell Renal Cancer

D. Berney, M. Gerlinger, I. Kayani, 2013, Clinical Cancer Research.

Abstract B46: NUC-3373: A novel pyrimidine nucleotide analogue that overcomes key cancer drug resistance limiting patient survival

D. Harrison, S. Blagden, E. Ghazaly, 2015 .

Beta1 integrin in tissue remodelling and repair: from phenomena to concepts.

D. Harrison, R. Al-Jamal, 2008, Pharmacology & therapeutics.

Edinburgh Research Explorer 5-hydroxymethylcytosine profiling as an indicator of cellular state

J. Thomson, R. Meehan, D. Harrison, 2013 .

Inhibition of tumour necrosis factor alpha does not prevent experimental paracetamol‐induced hepatic necrosis

R. Strieter, D. Harrison, S. Kunkel, 2000, The Journal of pathology.

Human urinary exosomes in bladder cancer patients: properties, concentrations and possible clinical application

D. Harrison, A. Riches, L. McLornan, 2016 .

Human tissue in systems medicine

P. Caie, A. Oniscu, D. Harrison, 2013, The FEBS journal.

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

W. Bickmore, E. C. Schirmer, S. Boyle, 2013, Genome Biology.