Michelle S Prew

High-fidelity CRISPR-Cas9 variants with undetectable genome-wide off-targets

J. Joung, V. Pattanayak, S. Tsai, 2015, Nature.

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

J. Joung, S. Tsai, V. Topkar, 2015, Nature Biotechnology.

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

Martin J. Aryee, Martin J Aryee, Zachary R McCaw, 2016, Nature Biotechnology.

The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core

Michelle S Prew, L. Walensky, T. Wales, 2021, Nature Communications.

Allele-Specific CRISPR-Cas9 Genome Editing of the Single-Base P23H Mutation for Rhodopsin-Associated Dominant Retinitis Pigmentosa.

J. Joung, B. Kleinstiver, Michelle S Prew, 2018, The CRISPR journal.

Genome-wide specificity profiles of CRISPR-Cas Cpf1 nucleases in human cells

Moira M. Welch, J. Joung, S. Tsai, 2016, bioRxiv.

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

H. Seo, Michelle S Prew, C. M. Camara, 2022, Nature Communications.

MCL-1 is a master regulator of cancer dependency on fatty acid oxidation

S. Gygi, J. Opferman, J. Paulo, 2022, Cell reports.