Yin-Biao Sun

发表

X-ray diffraction studies of the contractile mechanism in single muscle fibres.

A. Stewart, G. Piazzesi, V. Lombardi, 2004, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

The myosin motor in muscle generates a smaller and slower working stroke at higher load

A. Stewart, G. Piazzesi, V. Lombardi, 2004, Nature.

Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle

Yin-Biao Sun, M. Irving, Xuemeng Zhang, 2017, eLife.

Regulatory domain of troponin moves dynamically during activation of cardiac muscle

Yin-Biao Sun, T. Kampourakis, Ivanka R Sevrieva, 2014, Journal of molecular and cellular cardiology.

Structural changes in troponin in response to Ca2+ and myosin binding to thin filaments during activation of skeletal muscle

Yin-Biao Sun, M. Irving, B. Brandmeier, 2006, Proceedings of the National Academy of Sciences.

Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament

Yin-Biao Sun, M. Irving, Xuemeng Zhang, 2017, The Journal of physiology.

Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle

Yin-Biao Sun, M. Irving, T. Kampourakis, 2019, Proceedings of the National Academy of Sciences.

15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism

F. Fraternali, W. Yue, Yin-Biao Sun, 2019, Communications Biology.

Novel myosin-based therapies for congenital cardiac and skeletal myopathies

Yin-Biao Sun, J. Ochala, 2016, Journal of Medical Genetics.

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I

K. Campbell, M. Gautel, Yin-Biao Sun, 2020, The Journal of Biological Chemistry.

Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion

Aiwu Zhou, R. Carrell, Yin-Biao Sun, 2020, Biomolecules.

Toward protein structure in situ: comparison of two bifunctional rhodamine adducts of troponin C.

B. Sykes, Yin-Biao Sun, M. Irving, 2007, Biophysical journal.

In situ orientations of protein domains: troponin C in skeletal muscle fibers.

B. Sykes, P. Mercier, Yin-Biao Sun, 2003, Molecular cell.

In Vitro and in Situ Structure and Function of the Cardiac Troponin C Familial Hypertrophic Cardiomyopathy-Linked Mutation, L29Q

I. M. Robertson, B. Sykes, Yin-Biao Sun, 2014 .

Phosphorylation-dependent interactions of myosin-binding protein C and troponin coordinate the myofilament response to protein kinase A

Yin-Biao Sun, M. Irving, T. Kampourakis, 2022, The Journal of biological chemistry.

Structural dynamics of troponin during activation of skeletal muscle

Yin-Biao Sun, M. Irving, L. Fusi, 2014, Proceedings of the National Academy of Sciences.

Conformation of the troponin core complex in the thin filaments of skeletal muscle during relaxation and active contraction.

Yin-Biao Sun, M. Irving, A. C. Knowles, 2012, Journal of molecular biology.

A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex.

I. M. Robertson, B. Sykes, Yin-Biao Sun, 2010, Journal of molecular and cellular cardiology.

Actomyosin energy turnover declines while force remains constant during isometric muscle contraction

Yin-Biao Sun, M. Irving, Timothy G. West, 2004, The Journal of physiology.

Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments

Yin-Biao Sun, M. Irving, T. Kampourakis, 2016, Proceedings of the National Academy of Sciences.

The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q

I. M. Robertson, B. Sykes, Yin-Biao Sun, 2015, Journal of molecular and cellular cardiology.

Calcium‐ and myosin‐dependent changes in troponin structure during activation of heart muscle

Malcolm Irving, Yin-Biao Sun, M. Irving, 2009, The Journal of physiology.

Reversible Covalent Binding to Cardiac Troponin C by the Ca2+-Sensitizer Levosimendan.

I. M. Robertson, B. Sykes, Yin-Biao Sun, 2016, Biochemistry.

Orientation of the N- and C-Terminal Lobes of the Myosin Regulatory Light Chain in Cardiac Muscle

Yin-Biao Sun, M. Irving, T. Kampourakis, 2015, Biophysical journal.

Orientation of the N-terminal lobe of the myosin regulatory light chain in skeletal muscle fibers.

Yin-Biao Sun, M. Irving, D. Trentham, 2012, Biophysical journal.

Uncoordinated Transcription and Compromised Muscle Function in the Lmna-Null Mouse Model of Emery-Dreifuss Muscular Dystrophy

Robert B. White, Juliet A. Ellis, Yin-Biao Sun, 2011, PloS one.

Probing the mechanism of cardiovascular drugs using a covalent levosimendan analog

I. M. Robertson, B. Sykes, Yin-Biao Sun, 2016, Journal of molecular and cellular cardiology.

15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism

F. Fraternali, W. Yue, Yin-Biao Sun, 2019, Communications Biology.

Reversible Covalent Reaction of Levosimendan with Cardiac Troponin C in Vitro and in Situ.

Brittney A. Klein, I. M. Robertson, B. Sykes, 2018, Biochemistry.

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells

M. Gautel, Yin-Biao Sun, M. Irving, 2014, Proceedings of the National Academy of Sciences.

Structural and functional effects of myosin-binding protein-C phosphorylation in heart muscle are not mimicked by serine-to-aspartate substitutions

Yin-Biao Sun, M. Irving, T. Kampourakis, 2018, The Journal of Biological Chemistry.

The molecular basis of the steep force–calcium relation in heart muscle

Malcolm Irving, Yin-Biao Sun, M. Irving, 2010, Journal of molecular and cellular cardiology.

Structure‐Function Relation of the Myosin Motor in Striated Muscle

A. Stewart, G. Piazzesi, V. Lombardi, 2005, Annals of the New York Academy of Sciences.

Skeletal muscle resists stretch by rapid binding of the second motor domain of myosin to actin

G. Piazzesi, V. Lombardi, M. Reconditi, 2007, Proceedings of the National Academy of Sciences.

Conformation of the myosin motor during force generation in skeletal muscle.

G. Piazzesi, V. Lombardi, I. Dobbie, 2000 .

Mechanism of force generation by myosin heads in skeletal muscle

G. Piazzesi, V. Lombardi, M. Reconditi, 2002, Nature.

Conformation of the myosin motor during force generation in skeletal muscle

G. Piazzesi, V. Lombardi, I. Dobbie, 2000, Nature Structural Biology.

Studies of Mechanical Properties and Intracellular Ca2+ Transients in Frog Single Muscle Fibres

Yin-Biao Sun, 1996 .

X-ray diffraction studies of the contractilemechanism in singlemuscle fibres

A. Stewart, G. Piazzesi, V. Lombardi, 2005 .

Effects of sarcomere length and temperature on the rate of ATP utilisation by rabbit psoas muscle fibres

Yin-Biao Sun, Malcolm Irving, Karlheinz Hilber, 2001, The Journal of physiology.

Interference X-ray Diffraction from Single Muscle Cells Reveals the Molecular Basis of Muscle Braking

G. Piazzesi, V. Lombardi, M. Reconditi, 2011 .