B. Janji

发表

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

C. Hoffmann, X. Mao, M. Dieterle, 2016, Oncotarget.

Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia.

S. Terry, B. Janji, S. Chouaib, 2015, American journal of physiology. Cell physiology.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells.

P. Romero, B. Janji, F. Mami-Chouaib, 2012, Cancer research.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

The Critical Role of Hypoxia in Tumor-Mediated Immunosuppression

B. Janji, N. Aouali, M. Bosseler, 2017 .

Autophagy Activation in the Tumor Microenvironment: A Major Process in Shaping the Antitumor Immune Response

G. Berchem, B. Janji, E. Viry, 2016 .

Autophagy Regulation of the Tumor Immunity – An Old Machinery for a New Function

B. Janji, S. Chouaib, Guy Berchem Kris Van Moer, 2015 .

Promoter characterization and genomic organization of the gene encoding integrin-linked kinase 1.

B. Janji, N. Kieffer, S. Kreis, 2002, Biochimica et biophysica acta.

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

S. Niclou, N. Heveker, B. Janji, 2019, Cells.

Actin-filament cross-linking protein T-plastin increases Arp2/3-mediated actin-based movement

B. Janji, C. Ampe, C. Sykes, 2005, Journal of Cell Science.

The emerging impact of autophagy on the antitumor immune response

G. Berchem, B. Janji, C. Duhem, 2020 .

Hypoxia: A Formidable Saboteur of the Anti-tumor Response

S. Terry, B. Janji, S. Chouaib, 2015 .

Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway

S. Haan, B. Janji, P. Nazarov, 2019, Autophagy.

Editor's Note: ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy.

D. Olive, C. Richon, B. Janji, 2022, Cancer research.

The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing*

B. Janji, S. Chouaib, M. Noman, 2015, The Journal of Biological Chemistry.

Carbonic Anhydrase IX: A Renewed Target for Cancer Immunotherapy

B. Janji, G. Chalbatani, Ghanbar Mahmoodi Chalbatani, 2022, Cancers.

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

S. Niclou, A. Oudin, G. Berchem, 2018, Blood.

Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy

G. Berchem, B. Janji, S. Chouaib, 2021, Oncogene.

Autophagy: an adaptive metabolic response to stress shaping the antitumor immunity.

G. Berchem, B. Janji, J. Bagińska, 2014, Biochemical pharmacology.

The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing*

B. Janji, S. Chouaib, M. Noman, 2015, The Journal of Biological Chemistry.

Microenvironment and Immunology Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells

P. Romero, B. Janji, F. Mami-Chouaib, 2012 .

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

P. Romero, G. Berchem, B. Janji, 2011, Cancer research.

inducing autophagy ITPR 1 protects renal cancer cells against natural killer cells

Katy, Catherine, Betty, 2014 .

The Promise of Targeting Hypoxia to Improve Cancer Immunotherapy: Mirage or Reality?

B. Janji, S. Chouaib, 2022, Frontiers in Immunology.

Emerging Role of Hypoxia-Induced Autophagy in Cancer Immunotherapy

G. Berchem, B. Janji, S. Chouaib, 2014 .

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

J. Zimmer, S. Niclou, A. Poli, 2013, Proceedings of the National Academy of Sciences.

Epigenetic Activity of Peroxisome Proliferator-Activated Receptor Gamma Agonists Increases the Anticancer Effect of Histone Deacetylase Inhibitors on Multiple Myeloma Cells

G. Berchem, B. Janji, O. Keunen, 2015, PloS one.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT

F. Azuaje, J. Thiery, L. Tranchevent, 2017, Oncoimmunology.

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

T. Tan, J. Thiery, S. Terry, 2017, Oncoimmunology.

The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model

A. Oudin, G. Berchem, B. Janji, 2022, Cells.

The Histone Deacetylase Inhibitor MGCD0103 Induces Apoptosis in B-Cell Chronic Lymphocytic Leukemia Cells through a Mitochondria-Mediated Caspase Activation Cascade

G. Berchem, B. Janji, N. Brons, 2010, Molecular Cancer Therapeutics.

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy

G. Berchem, B. Janji, S. Parpal, 2020, Science Advances.

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

G. Berchem, B. Janji, E. Le Cam, 2015, Oncoimmunology.

Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter

M. Khaled, B. Janji, F. Mami-Chouaib, 2017, The Journal of Immunology.

CMTM6 and CMTM7: New leads for PD‐L1 regulation in breast cancer cells undergoing EMT

G. Berchem, B. Janji, C. Duhem, 2022, Journal of cellular biochemistry.

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

J. Thiery, B. Janji, F. Mami-Chouaib, 2013, Autophagy.

The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B

B. Janji, B. Volkman, T. Laeremans, 2022, Frontiers in Immunology.

The β-carboline Harmine improves the therapeutic benefit of anti-PD1 in melanoma by increasing the MHC-I-dependent antigen presentation

G. Berchem, B. Janji, M. Noman, 2022, Frontiers in Immunology.

Firing up the cold tumors by targeting Vps34

G. Berchem, B. Janji, S. Parpal, 2020, Oncoimmunology.

Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-β1 stimulation

B. Janji, N. Kieffer, L. Vallar, 2000, Oncogene.

The actin filament cross-linker L-plastin confers resistance to TNF-α in MCF-7 breast cancer cells in a phosphorylation-dependent manner

G. Berchem, B. Janji, S. Chouaib, 2009, Journal of cellular and molecular medicine.

CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6

G. Berchem, B. Janji, M. Ollert, 2021, Cancers.

EGF controls the in vivo developmental potential of a mammary epithelial cell line possessing progenitor properties

J. Thiery, B. Janji, M. Glukhova, 2002, The Journal of cell biology.

Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target

G. Berchem, B. Janji, M. Noman, 2018, Oncoimmunology.

Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield

G. Berchem, B. Janji, M. Noman, 2018, Autophagy.

Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner

C. Robert, G. Berchem, B. Janji, 2017, Proceedings of the National Academy of Sciences.

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

G. Dittmar, Alexei Vazquez, B. Janji, 2022, Nature Communications.

Mitochondrial One-Carbon Flux has a Growth-Independent Role in Promoting Breast Cancer Metastasis

A. Vazquez, G. Dittmar, B. Janji, 2021 .

Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34

G. Berchem, B. Janji, S. Parpal, 2020, Autophagy.

Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response.

B. Janji, S. Chouaib, M. Noman, 2011, Critical reviews in immunology.

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A

S. Niclou, A. Oudin, B. Janji, 2017, British Journal of Cancer.

ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy.

D. Olive, C. Richon, B. Janji, 2014, Cancer research.

The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity

G. Berchem, B. Janji, J. Bagińska, 2013, Front. Immunol..

Peroxisome proliferator‐activated receptor γ agonists potentiate the cytotoxic effect of valproic acid in multiple myeloma cells

G. Berchem, B. Janji, N. Brons, 2009, British journal of haematology.

High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia

G. Berchem, B. Janji, J. Paggetti, 2018, Oncoimmunology.

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

P. Dessen, B. Janji, S. Chouaib, 2014, The Journal of experimental medicine.

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

T. Tan, J. Thiery, F. André, 2013, Cancer research.

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

P. Lichter, E. Solary, Franziska Haderk, 2015, Blood.

Autocrine TGF‐β‐regulated expression of adhesion receptors and integrin‐linked kinase in HT‐144 melanoma cells correlates with their metastatic phenotype

B. Janji, N. Kieffer, L. Vallar, 1999, International journal of cancer.

Phosphorylation on Ser5 increases the F-actin-binding activity of L-plastin and promotes its targeting to sites of actin assembly in cells

E. Bruyneel, B. Janji, J. Gettemans, 2006, Journal of Cell Science.

Actin Cytoskeleton Remodeling Drives Breast Cancer Cell Escape from Natural Killer-Mediated Cytotoxicity.

J. Thiery, C. Hoffmann, X. Mao, 2018, Cancer research.

Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot

R. Langer, L. Eckhart, M. Tschan, 2020, Biology.

Chapter 9 Role of Autophagy in Cancer and Tumor Progression

G. Berchem, B. Janji, J. Bagińska, 2013 .

Human CD56dimCD16dim Cells As an Individualized Natural Killer Cell Subset

T. Michel, J. Zimmer, A. Poli, 2017, Front. Immunol..

Role of Autophagy in Cancer and Tumor Progression

G. Berchem, B. Janji, J. Bagińska, 2013 .

Improving Cancer Immunotherapy by Targeting the Hypoxic Tumor Microenvironment: New Opportunities and Challenges

G. Berchem, B. Janji, S. Chouaib, 2019, Cells.

Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints.

G. Berchem, B. Janji, M. Noman, 2019, Cancer letters.

miR-210 and hypoxic microvesicles: Two critical components of hypoxia involved in the regulation of killer cells function.

G. Berchem, B. Janji, S. Chouaib, 2016, Cancer letters.

The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom microarray

G. Berchem, B. Janji, S. Chouaib, 2011, Autophagy.

Tumor plasticity interferes with anti-tumor immunity.

J. Thiery, A. Eggermont, B. Janji, 2014, Critical reviews in immunology.

Resistance of Tumor Cells to Cytolytic T Lymphocytes Involves Rho-GTPases and Focal Adhesion Kinase Activation*

B. Janji, F. Mami-Chouaib, S. Chouaib, 2008, Journal of Biological Chemistry.

miR-181a modulates acute myeloid leukemia susceptibility to natural killer cells

J. Bourhis, D. Olive, P. Dessen, 2015, Oncoimmunology.

Inhibition of HIF1α-Dependent Upregulation of Phospho-l-Plastin Resensitizes Multiple Myeloma Cells to Frontline Therapy

G. Berchem, B. Janji, T. Kaoma, 2018, International journal of molecular sciences.

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

J. Westermarck, R. Bjerkvig, B. Janji, 2018, International journal of cancer.

Targeting Cytoprotective Autophagy to Enhance Anticancer Therapies

G. Berchem, B. Janji, C. Duhem, 2021, Frontiers in Oncology.

Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression

T. Tan, J. Thiery, B. Janji, 2014, Oncogene.

Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity

G. Berchem, B. Janji, S. Chouaib, 2018, Front. Immunol..

The multifaceted role of autophagy in tumor evasion from immune surveillance

G. Berchem, B. Janji, F. Mami-Chouaib, 2016, Oncotarget.

Activation of NK cells and disruption of PD-L1/PD-1 axis: two different ways for lenalidomide to block myeloma progression

G. Berchem, B. Janji, M. Giuliani, 2017, Oncotarget.

SNAI1-dependent upregulation of CD73 increases extracellular adenosine release to mediate immune suppression in TNBC

J. Thiery, G. Berchem, B. Janji, 2022, Frontiers in Immunology.

Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet

G. Berchem, B. Janji, S. Chouaib, 2016, Frontiers in oncology.

Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status.

S. Richard, G. Le Teuff, B. Janji, 2016, European urology.

Selection of tumor-resistant variants following sustained natural killer cell-mediated immune stress

S. Terry, D. Olive, B. Janji, 2020, Oncology reports.

Tumor-Promoting Effects of Myeloid-Derived Suppressor Cells Are Potentiated by Hypoxia-Induced Expression of miR-210.

F. Martelli, B. Janji, S. Chouaib, 2015, Cancer research.

Epithelial to Mesenchymal Transition Regulates Surface PD-L1 via CMTM6 and CMTM7 Induction in Breast Cancer

T. Tan, J. Thiery, C. Gilles, 2021, Cancers.

CRP 2 , a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

X. Mao, M. Dieterle, F. Moreau, 2016 .

Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune?

G. Berchem, B. Janji, S. Chouaib, 2010, Tissue antigens.

Rapid tumor development and potent vascularization are independent events in carcinoma producing FGF-1 or FGF-2

C. Billottet, J. Thiery, J. Jouanneau, 2002, Oncogene.

Abstract 2116: VPS34 inhibitor SB02024 activates cGAS-STING signaling and sensitizes tumors to STING agonist

A. Alexeyenko, B. Janji, S. Parpal, 2022, Cancer Research.

“Suffocating” tumors by blocking adaptation to hypoxia: a new headway in melanoma immunotherapy

B. Janji, S. Chouaib, 2021, Oncoimmunology.

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

C. Hoffmann, X. Mao, F. Moreau, 2018, Scientific Reports.

Role of Autophagy in Tumor Progression and Regression

B. Janji, S. Chouaib, 2016 .

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Autophagic degradation of GZMB/granzyme B

G. Berchem, B. Janji, S. Chouaib, 2014, Autophagy.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Driving Cytotoxic Natural Killer Cells into Melanoma: If CCL5 Plays the Music, Autophagy Calls the Shots.

G. Berchem, B. Janji, M. Ollert, 2018, Critical reviews in oncogenesis.

Lighting Up the Fire in the Microenvironment of Cold Tumors: A Major Challenge to Improve Cancer Immunotherapy

G. Berchem, B. Janji, C. Duhem, 2023, Cells.

The autophagy sensor ITPR1 protects renal carcinoma cells from NK-mediated killing.

B. Janji, S. Chouaib, M. Noman, 2015, Autophagy.

Role of hypoxia induced autophagy in the resistance of tumor cells to CTL-mediated specific lysis. (95.11)

G. Berchem, B. Janji, F. Mami-Chouaib, 2010, The Journal of Immunology.

Hypoxia-induced autophagy

G. Berchem, B. Janji, F. Mami-Chouaib, 2012, Autophagy.

A role for EMT in CD73 regulation in breast cancer

G. Berchem, B. Janji, M. Hasmim, 2022, Oncoimmunology.

Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from

T. Tan, J. Thiery, B. Janji, 2013 .

Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2

C. Hoffmann, X. Mao, F. Moreau, 2018, Scientific Reports.

Guidelines for the use and interpretation of assays for monitoring autophage

T. P. Neufeld, Thomas J. Begley, H. Coller, 2012 .

Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden: Impact on cancer immunotherapy.

B. Janji, J. Thiery, P. Limani, 2023, Seminars in cancer biology.

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

T. Tan, J. Thiery, F. André, 2013, Cancer research.

Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy

G. Berchem, B. Janji, E. Viry, 2014 .

The Histone Deacetylase Inhibitor MGCD0103 Induces Apoptosis in B-Cell Chronic Lymphocytic Leukemia Cells through a Mitochondria-Mediated Caspase Activation Cascade

G. Berchem, B. Janji, N. Brons, 2010, Molecular Cancer Therapeutics.

EGF controls the in vivo developmental potential of a mammary epithelial cell line possessing progenitor properties

J. Thiery, B. Janji, M. Glukhova, 2002, The Journal of cell biology.

Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti‐tumor efficacy

A. Alexeyenko, B. Janji, S. Parpal, 2024, Molecular oncology.

PD-L1 is a novel direct target of HIF-1  , and its blockade under hypoxia enhanced MDSC-mediated T cell

B. Janji, S. Chouaib, M. Noman, 2014 .