D. Fleisher

发表

Absorption potential: estimating the fraction absorbed for orally administered compounds.

G. Amidon, J. Dressman, D. Fleisher, 1985, Journal of pharmaceutical sciences.

Intestinal metabolism and transport of 5-aminosalicylate.

D. Fleisher, S. Y. Zhou, L. Pao, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Drug Absorption With Food

D. Fleisher, B. V. Sweet, J. Boullata, 2009 .

Absorption of ACE inhibitors from small intestine and colon.

J. Dressman, D. Fleisher, J. Kim, 1994, Journal of pharmaceutical sciences.

Design of prodrugs for improved gastrointestinal absorption by intestinal enzyme targeting.

G. Amidon, D. Fleisher, B. H. Stewart, 1985, Methods in enzymology.

Regulation of Paracellular Absorption of Cimetidine and 5-Aminosalicylate in Rat Intestine

D. Fleisher, S. Zhou, L. Pao, 1999, Pharmaceutical Research.

Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: possible role in dose-dependent pharmacokinetics.

D. Fleisher, T. Heimbach, A. Kaddoumi, 2006, Journal of pharmaceutical sciences.

Meal Composition Effects on the Oral Bioavailability of Indinavir in HIV-Infected Patients

D. Fleisher, S. Zhou, D. Kaul, 1999, Pharmaceutical Research.

Food-Drug Interactions: Drug Development Considerations

D. Fleisher, L. Reynolds, 2004 .

Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.

G. Amidon, D. Fleisher, T. Heimbach, 2002, The Journal of pharmacology and experimental therapeutics.

Modeling drug release from dynamically swelling poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels

G. Amidon, D. Fleisher, J. Kou, 1990 .

Comparison of gastrointestinal pH in dogs and humans: implications on the use of the beagle dog as a model for oral absorption in humans.

G. Amidon, J. Dressman, D. Fleisher, 1986, Journal of pharmaceutical sciences.

Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein

G. Amidon, D. Fleisher, Duxin Sun, 2001, AAPS PharmSci.

In Vivo Effects of Glycyl-Glutamate and Glycyl-Sarcosine on Gabapentin Oral Absorption in Rat

D. Fleisher, David E. Smith, Theresa V. Nguyen, 2007, Pharmaceutical Research.

Topical delivery of growth hormone releasing peptide using liposomal systems: an in vitro study using hairless mouse skin.

N. Weiner, C. Ramachandran, D. Fleisher, 1995, Life sciences.

Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model

D. Fleisher, S. Niemiec, F. Kesisoglou, 2005, Pharmaceutical Research.

PEPT1 Enhances the Uptake of Gabapentin via Trans-Stimulation of b0,+ Exchange

D. Fleisher, David E. Smith, Theresa V. Nguyen, 2007, Pharmaceutical Research.

Influence of D-glucose-induced water absorption on rat jejunal uptake of two passively absorbed drugs.

D. Fleisher, J. Thomas, H. H. Lu, 1992, Journal of pharmaceutical sciences.

PH-induced nanosegregation of ritonavir to lyotropic liquid crystal of higher solubility than crystalline polymorphs.

N. Rodríguez-Hornedo, D. Fleisher, Barbara Rodríguez-Spong, 2008, Molecular pharmaceutics.

Cimetidine sulfoxidation in small intestinal microsomes.

D. Fleisher, C. Li, X. Lu, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Drug, Meal and Formulation Interactions Influencing Drug Absorption After Oral Administration

D. Fleisher, L. Pao, A. Karim, 1999, Clinical pharmacokinetics.

Application of a radiotelemetric system to evaluate the performance of enteric coated and plain aspirin tablets.

G. Amidon, D. Fleisher, R. Oberle, 1986, Journal of pharmaceutical sciences.

Overcoming Poor Aqueous Solubility of Drugs for Oral Delivery

Tycho Heimbach, D. Fleisher, T. Heimbach, 2007 .

Transdermal delivery of drugs for the treatment of bone diseases.

C. Ramachandran, D. Fleisher, 2000, Advanced drug delivery reviews.

Mucosal Uptake of Gabapentin (Neurontin) vs. Pregabalin in the Small Intestine

D. Fleisher, N. Piyapolrungroj, H. Bockbrader, 2001, Pharmaceutical Research.

Restituting intestinal epithelial cells exhibit increased transducibility by adenoviral vectors

D. Fleisher, B. Roessler, F. Kesisoglou, 2006, The journal of gene medicine.

Reduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorption

Carol F. Kirchhoff, D. Fleisher, S. Zhou, 1998, Pharmaceutical Research.

Noncompetitive inhibition of cephradine uptake by enalapril in rabbit intestinal brush-border membrane vesicles: an enalapril specific inhibitory binding site on the peptide carrier.

G. Amidon, D. Fleisher, H. Yuasa, 1994, The Journal of pharmacology and experimental therapeutics.

Improved oral drug delivery: solubility limitations overcome by the use of prodrugs

D. Fleisher, B. H. Stewart, Barbra H. Stewart, 1996 .

Intestinal Water and Solute Absorption Studies: Comparison of in Situ Perfusion with Chronic Isolated Loops in Rats

D. Fleisher, J. Tukker, Hsiao-Hwa Lu, 1992, Pharmaceutical Research.

Discrimination between drug candidates using models for evaluation of intestinal absorption

O. H. Chan, D. Fleisher, B. H. Stewart, 1997 .

Transport of Pregabalin in Rat Intestine and Caco-2 Monolayers

D. Fleisher, B. H. Stewart, H. Bockbrader, 1999, Pharmaceutical Research.

Contrasting nutrient effects on the plasma levels of an amino acid-like antiepileptic agent from jejunal administration in dogs.

D. Fleisher, H. Bockbrader, C. Stevenson, 1997, Journal of pharmaceutical sciences.

Estimating Human Oral Fraction Dose Absorbed: A Correlation Using Rat Intestinal Membrane Permeability for Passive and Carrier-Mediated Compounds

Patrick J. Sinko, Gordon L. Amidon, G. Amidon, 2004, Pharmaceutical Research.

Physicochemical model for dose-dependent drug absorption.

G. Amidon, J. Dressman, D. Fleisher, 1984, Journal of pharmaceutical sciences.

Calculation of the Aqueous Diffusion Layer Resistance for Absorption in a Tube: Application to Intestinal Membrane Permeability Determination

G. Amidon, D. Fleisher, J. Kou, 1991, Pharmaceutical Research.

Absorption Rate Limit Considerations for Oral Phosphate Prodrugs

G. Flynn, J. Leppänen, D. Fleisher, 2003, Pharmaceutical Research.

Nutrient Influences on Rat Intestinal Phenytoin Uptake

D. Fleisher, N. Sheth, Martin McFadden, 1989, Pharmaceutical Research.

Cimetidine absorption and elimination in rat small intestine.

D. Fleisher, C. Li, E. Zimmermann, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Nutrient effects on intestinal drug absorption.

D. Fleisher, C. Reppas, N. Sheth, 1990 .

Fed-state effects on zidovudine absorption.

D. Fleisher, P. Sinko, H. Lu, 1991, AIDS.

Oral absorption of 21-corticosteroid esters: a function of aqueous stability and intestinal enzyme activity and distribution.

G. Amidon, D. Fleisher, B. H. Stewart, 1986, Journal of pharmaceutical sciences.

Comparison of Human Duodenum and Caco-2 Gene Expression Profiles for 12,000 Gene Sequences Tags and Correlation with Permeability of 26 Drugs

Gordon L. Amidon, Duxin Sun, G. Amidon, 2002, Pharmaceutical Research.

CCK antagonist pre-treatment inhibits meal-enhanced drug absorption in dogs

D. Fleisher, P. Dickson, C. Lippert, 1997, Regulatory Peptides.

Cimetidine transport in brush-border membrane vesicles from rat small intestine.

D. Fleisher, R. Pisoni, C. Li, 1999, The Journal of pharmacology and experimental therapeutics.

Intestinal clearance of H2-antagonists.

D. Fleisher, Y. Hui, Z. Hu, 1994, Biochemical pharmacology.

Regional-dependent intestinal absorption and meal composition effects on systemic availability of LY303366, a lipopeptide antifungal agent, in dogs.

D. Fleisher, V. Vasudevan, S. Y. Zhou, 2001, Journal of pharmaceutical sciences.

The Role of Rheological Properties in Mucociliary Transport by Frog Palate Ciliated Model

N. Weiner, G. Amidon, D. Fleisher, 1994, Pharmaceutical Research.

Biological Transport Phenomena in the Gastrointestinal Tract: Cellular Mechanisms

D. Fleisher, 1999 .

Phenytoin interaction with enteral feedings administered through nasogastric tubes.

D. Fleisher, J. Kou, N. Sheth, 1990, JPEN. Journal of parenteral and enteral nutrition.

Mixing-tank model for predicting dissolution rate control or oral absorption.

J. Dressman, D. Fleisher, J B Dressman, 1986, Journal of pharmaceutical sciences.

Colonic Absorption of Antiepileptic Agents

D. Fleisher, D Fleisher, C M Stevenson, 1997, Epilepsia.

Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction.

D. Fleisher, F. Kesisoglou, E. Zimmermann, 2010, Molecular pharmaceutics.

Enzyme-mediated precipitation of parent drugs from their phosphate prodrugs.

N. Rodríguez-Hornedo, D. Fleisher, T. Heimbach, 2003, International journal of pharmaceutics.

Intestinal absorption of amino acid derivatives: importance of the free alpha-amino group.

G. Amidon, D. Fleisher, R. Allen, 1982, Journal of pharmaceutical sciences.

Release of Phenylpropanolamine from Dynamically Swelling Póly-(Hydroxyethyl Methacrylate-Co-Methacrylic Acid) Hydrogels

G. Amidon, D. Fleisher, J. H. Kou, 1991 .

Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction.

D. Fleisher, F. Kesisoglou, E. Zimmermann, 2010, Molecular pharmaceutics.