B. Hirst

B. Hirst, S. Lowes, Lauretta M S Chan, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Predicting oral drug absorption and hepatobiliary clearance: Human intestinal and hepatic in vitro cell models.

B. Hirst, Richard A Fearn, 2006, Environmental toxicology and pharmacology.

Molecular and Cellular Mechanisms of H+ Transport

B. Hirst, 2011, NATO ASI Series.

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators.

T. Tsuruo, B. Hirst, N. Simmons, 1993, The Journal of biological chemistry.

Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.

D. Thwaites, B. Hirst, N. Simmons, 1993, The Journal of biological chemistry.

Ion transport by human endometrial epithelia in vitro.

E. Thomas, B. Hirst, C. Redfern, 1993, Human reproduction.

Printed in Great Britain RELATIONSHIP BETWEEN HYDROGEN ION CONCENTRATION AND FLOW OF GASTRIC JUICE DURING INHIBITION OF GASTRIC SECRETION IN THE CAT BY B. H. HIRST, L. A. LABIB, THE LATE J. D. REED

B. Hirst, L. A. Labib, J. D. Reed, 2005 .

Heterogenous Na+, K+-ATPase expression in the epithelia of rabbit gut-associated lymphoid tissues

B. Hirst, N. Simmons, M. Jepson, 1994, Pflügers Archiv.

Epithelial M cells in the rabbit caecal lymphoid patch display distinctive surface characteristics

B. Hirst, N. Simmons, M. Jepson, 1993, Histochemistry.

Paracellular barrier and junctional protein distribution depend on basolateral extracellular Ca2+ in cultured epithelia.

B. Hirst, N. Simmons, M. Jepson, 1994, Biochimica et biophysica acta.

BROMOCRIPTINE POTENTIATION OF GASTRIC ACID SECRETION IN CATS

B. Hirst, A. Gómez-Pan, L. A. Labib, 1976, Clinical endocrinology.

Targeted expression of microbial cellulases in transgenic animals

Harry J. Gilbert, Judith Hall, B. Hirst, 1995 .

Identification of M cells and their distribution in rabbit intestinal Peyer's patches and appendix

B. Hirst, N. Simmons, G. Hirst, 1993, Cell and Tissue Research.

Transepithelial secretion, cellular accumulation and cytotoxicity of vinblastine in defined MDCK cell strains.

B. Hirst, N. Simmons, J. Hunter, 1993, Biochimica et biophysica acta.

Exploiting receptor biology for oral vaccination with biodegradable particulates.

B. Hirst, N. Foster, 2005, Advanced drug delivery reviews.

The use of chimeric gene constructs to express a bacterial endoglucanase in mammalian cells.

J. Hall, B. Hirst, H. Gilbert, 1992, Biochimica et biophysica acta.

Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic

D. Thwaites, B. Hirst, N. Simmons, 1993, Pflügers Archiv.

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

D. Thwaites, B. Hirst, N. Simmons, 1998, The Journal of physiology.

Dietary regulation of intestinal nutrient carriers

B. Hirst, 1993, Proceedings of the Nutrition Society.

Autocrine stimulation of growth of AR4-2J rat pancreatic tumour cells by gastrin.

B. Hirst, M. Blackmore, B. H. Hirst, 1992, British journal of cancer.

EFFECTS OF A COMBINED OESTROGEN‐PROGESTIN PREPARATION ON GASTRIC ACID AND PEPSIN SECRETION, SERUM GASTRIN CONCENTRATION AND BILIARY SECRETION OF BILE ACIDS, PHOSPHOLIPIDS, AND CHOLESTEROL IN THE CAT

B. Hirst, B. Shaw, D. Sanders, 1979, British journal of pharmacology.

H(+)-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics.

D. Thwaites, B. Hirst, N. Simmons, 1993, Biochimica et biophysica acta.

Duodenal brush-border mucosal glucose transport and enzyme activities in aging man and effect of bacterial contamination of the small intestine

J. Mathers, B. Hirst, O. James, 1993, Digestive Diseases and Sciences.

Secretion of a prokaryotic cellulase in bacterial and mammalian cells.

J. Hall, B. Hirst, H. Gilbert, 1993, Gene.

Drug Absorption Limited by P-Glycoprotein-Mediated Secretory Drug Transport in Human Intestinal Epithelial Caco-2 Cell Layers

B. Hirst, N. Simmons, J. Hunter, 1993, Pharmaceutical Research.

Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo.

B. Hirst, M. Jepson, M. Clark, 1998, Vaccine.

Junctional uvomorulin/E-cadherin and phosphotyrosine-modified protein content are correlated with paracellular permeability in Madin-Darby canine kidney (MDCK) epithelia

B. Hirst, N. Simmons, M. Jepson, 1994, Histochemistry.

Expression of junction-associated proteins differentiates mouse intestinal M cells from enterocytes

B. Hirst, A. Clark, 2002, Histochemistry and Cell Biology.

L-Alanine absorption in human intestinal Caco-2 cells driven by the proton electrochemical gradient

D. Thwaites, B. Hirst, N. Simmons, 1994, The Journal of Membrane Biology.

D‐Cycloserine transport in human intestinal epithelial (Caco‐2) cells: mediation by a H + ‐coupled amino acid transporter

D. Thwaites, B. Hirst, N. Simmons, 1995, British journal of pharmacology.

H+-coupled α-methylaminoisobutyric acid transport in human intestinal Caco-2 cells

D. Thwaites, B. Hirst, N. Simmons, 1995 .

H+‐coupled (Na+‐independent) proline transport in human intestinal (Caco‐2) epithelial cell monolayers

D. Thwaites, B. Hirst, N. Simmons, 1993, FEBS letters.

Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells.

B. Hirst, N. Simmons, T. Gray, 1990, Biochemical and biophysical research communications.

Bradykinin stimulation of electrogenic ion transport in epithelial layers of cultured human endometrium

E. Thomas, B. Hirst, G. McEwan, 2004, Pflügers Archiv.

Co-culture of two MDCK strains with distinct junctional protein expression: a model for intercellular junction rearrangement and cell sorting

B. Hirst, N. Simmons, M. Jepson, 1998, Cell and Tissue Research.

Hypo-osmolar stimulation of transepithelial Cl- secretion in cultured human T84 intestinal epithelial layers.

B. Hirst, N. Simmons, G. McEwan, 1992, Biochimica et biophysica acta.

Variations in lectin binding properties of intestinal M cells.

B. Hirst, N. Simmons, M. Jepson, 1995, Journal of drug targeting.

Thyrotropin-Releasing Hormone (TRH) Uptake in Intestinal Brush-Border Membrane Vesicles: Comparison with Proton-Coupled Dipeptide and Na+-Coupled Glucose Transport

D. Thwaites, B. Hirst, N. Simmons, 1993, Pharmaceutical Research.

Passive Transepithelial Absorption of Thyrotropin-Releasing Hormone (TRH) via a Paracellular Route in Cultured Intestinal and Renal Epithelial Cell Lines

D. Thwaites, B. Hirst, N. Simmons, 1993, Pharmaceutical Research.

Effect of alcohols on gastric and small intestinal apical membrane integrity and fluidity.

B. Hirst, H. Ballard, J. Wilkes, 1988, Gut.

Substrate specificity of the di/tripeptide transporter in human intestinal epithelia (Caco‐2): identification of substrates that undergo H+‐coupled absorption

D. Thwaites, B. Hirst, N. Simmons, 1994, British journal of pharmacology.

Autocrine growth stimulation of human renal Wilms' tumour G401 cells by a gastrin‐like peptide

B. Hirst, M. Blackmore, Elaine Doherty, 1994, International journal of cancer.

Co-expression of vimentin and cytokeratins in M cells of rabbit intestinal lymphoid follicle-associated epithelium

B. Hirst, N. Simmons, M. Bennett, 2005, The Histochemical Journal.

Lectin-mediated mucosal delivery of drugs and microparticles.

B. Hirst, M. Jepson, M. Clark, 2000, Advanced drug delivery reviews.

Cell-Contact-Stimulated Formation of Filamentous Appendages by Salmonella typhimurium Does Not Depend on the Type III Secretion System Encoded by SalmonellaPathogenicity Island 1

Mark A. Jepson, Samuel I. Miller, B. Hirst, 1998, Infection and Immunity.

Fade and tachyphylaxis of gastric acid secretory response to pentagastrin in rat isolated gastric mucosa

B. Hirst, M. Parsons, J. Holland, 1988, British journal of pharmacology.

Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco‐2 cell layers

B. Hirst, N. Simmons, N. Griffiths, 1993, British journal of pharmacology.

Polytetraftuoroethylene (PTFE): a new material for the construction of gastrointestinal cannulae

C. Venables, B. Hirst, G. Storey, 1982, Laboratory animals.

Structure‐activity relationships of eighteen somatostatin analogues on gastric secretion.

B. Hirst, A. Schally, B. Shaw, 1978, The Journal of physiology.

Transepithelial vinblastine secretion mediated by P-glycoprotein is inhibited by forskolin derivatives.

B. Hirst, N. Simmons, J. Hunter, 1991, Biochemical and biophysical research communications.

Pili mediate specific adhesion of Streptococcus pyogenes to human tonsil and skin

B. Hirst, M. Kehoe, Wendy Smith, 2007, Cellular microbiology.

Amiloride sensitivity of proton-conductive pathways in gastric and intestinal apical membrane vesicles

B. Hirst, J. Wilkes, 1992, The Journal of Membrane Biology.

Gastroduodenal Epithelial Cells: The Role of the Apical Membrane in Mucosal Protection

B. Hirst, J. Latham, H. Ballard, 1987 .

Redistribution and characterization of (H+ + K+)-ATPase membranes from resting and stimulated gastric parietal cells.

B. Hirst, J. G. Forte, 1985, The Biochemical journal.

Increased expression of specific intestinal amino acid and peptide transporter mRNA in rats fed by TPN is reversed by GLP-2.

J. Walters, B. Hirst, R. Goodlad, 2004, The Journal of nutrition.

A European approach to clinical investigator training

B. Hirst, J. Boeynaems, C. Canivet, 2013, Front. Pharmacol..

Investigation of mechanism of fade of gastrin‐stimulated gastric acid secretion in the cat.

B. Hirst, 1988, The Journal of physiology.

Sensitivity of parietal cells to gastrin in the cat: comparison with man and dog.

B. Hirst, D. Sanders, P. Lund, 1980, Digestion.

Secretin and the exposition of hormonal control

Barry H Hirst, B. Hirst, 2004, The Journal of physiology.

BROMOCRIPTINE, GASTRIC ACID OUTPUT, AND GASTRIN SECRETION

R. Caldara, B. Hirst, D. Sanders, 1977, The Lancet.

Polycation-induced enhancement of epithelial paracellular permeability is independent of tight junctional characteristics.

B. Hirst, N. Simmons, M. Jepson, 1993, Biochimica et biophysica acta.

Postgraduate opportunities in research at NEAS

B. Hirst, J. Newton, A. Fox, 2010 .

Application of Cell Culture Systems to the Study of Drug Transport and Metabolism

K. Audus, B. Hirst, R. Borchardt, 1995 .

Water transport controversies – an overview

L. Reuss, B. Hirst, 2002, The Journal of physiology.

Comparison of LDH, (51)Cr, and BCECF efflux as indices of non-steroidal anti-inflammatory drug-induced toxicity in human gastro-intestinal (HGT-1, HCT-8 and T84) cell lines: BCECF efflux is not an index of plasma membrane integrity.

B. Hirst, T. Gray, E. Harpur, 1992, Toxicology in vitro : an international journal published in association with BIBRA.

Reduction of Rapid Proliferating Tumour Cell Lines by Inhibition of the Specific Glycine Transporter GLYT1

B. Hirst, A. Howard, Christine Garcia Bierhals, 2021, Biomedicines.

Structure-activity studies with somatostatin: role of lysine in positions 4 and 9 for gastric activity

B. Hirst, D. Coy, 1984, Regulatory Peptides.

Cyclic hexa- and pentapeptide somatostatin analogues with reduced gastric inhibitory activity

B. Hirst, D. Coy, E. Arilla, 1984, Peptides.

Enterocytes in the follicle-associated epithelia of rabbit small intestine display distinctive lectin-binding properties

B. Hirst, N. Simmons, M. Jepson, 1995, Histochemistry and Cell Biology.

Co-expression of vimentin and cytokeratins in M of rabbit intestinal lymphoid follicle-associated epithelium cells

B. Hirst, N. Simmons, M. Bennett, 1992 .

Prostaglandin protects against bile salt induced increases in proton permeation of duodenal brush border membrane.

B. Hirst, D. Zhao, 1991, Gut.

Characterisation of volume-activated ion transport across epithelial monolayers of human intestinal T84 cells

B. Hirst, N. Simmons, G. McEwan, 1993, Pflügers Archiv.

Carbachol stimulates Cl- secretion via activation of two distinct apical Cl- pathways in cultured human T84 intestinal epithelial monolayers.

B. Hirst, N. Simmons, G. McEwan, 1994, Biochimica et biophysica acta.

Volume‐activated Cl− secretion and transepithelial vinblastine secretion mediated by P‐glycoprotein are not correlated in cultured human T84 intestinal epithelial layers

B. Hirst, N. Simmons, G. McEwan, 1992, FEBS letters.

Gastric acid and pepsin-stimulating activity of non-sulphated fragments of gastrin in the cat.

E. L. Blair, B. Hirst, B. Shaw, 1980, Digestion.

SECRETIN STIMULATION OF GASTRIC MUCUS SECRETION IN THE CAT: THE VISCOSITY OF GASTRIC JUICE IN RELATION TO GLYCOPROTEIN STRUCTURE AND CONCENTRATION

B. Hirst, A. Allen, R. Kaura, 1981 .

Relationship between hydrogen ion concentration and flow of gastric juice during inhibition of gastric secretion in the cat.

B. Hirst, L. A. Labib, J. D. Reed, 1980, The Journal of physiology.

Quantitative PCR in the assessment of novel hepatic cell models

B. Hirst, A. Howard, C. Mowbray, 2015 .

The effect of anaesthesia on pentagastrin stimulated gastric acid secretion in the cat.

E. L. Blair, B. Hirst, J. D. Reed, 1978, The Journal of physiology.

K+ recycling and gastric acid secretion

B. Hirst, 2002, The Journal of physiology.

Comparison of bile salt perturbation of duodenal and jejunal isolated brush-border membranes.

B. Hirst, D. Zhao, 1990, Digestion.