N. Simmons

N. Simmons, L. Al-Nakkash, B. Argent, 1996, International journal of pancreatology : official journal of the International Association of Pancreatology.

Extracellular zinc stimulates a calcium-activated chloride conductance through mobilisation of intracellular calcium in renal inner medullary collecting duct cells

N. Simmons, J. Linley, M. Gray, 2006, Pflügers Archiv - European Journal of Physiology.

Kinetics and regulation of a Ca2+-activated Cl- conductance in mouse renal inner medullary collecting duct cells.

N. Simmons, M. Gray, S. Boese, 2004, American journal of physiology. Renal physiology.

Regulation of an Outwardly Rectifying Chloride Conductance in Renal Epithelial Cells by External and Internal Calcium

N. Simmons, M. Glanville, M. Gray, 2001, The Journal of Membrane Biology.

IDENTIFICATION OF A PURINE (P2) RECEPTOR LINKED TO ION TRANSPORT IN A CULTURED RENAL (MDCK) EPITHELIUM

N. Simmons, 1981, British journal of pharmacology.

Dietary regulation of ruminal bovine UT-B urea transporter expression and localization.

N. Simmons, C. Smith, A. Thistlethwaite, 2009, Journal of animal science.

Renal calcium stones: insights from the control of bone mineralization

N. Simmons, J. Sayer, S. Moochhala, 2008, Experimental physiology.

Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells.

S. Pearce, N. Simmons, J. Sayer, 2003, Biochemical and biophysical research communications.

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators.

T. Tsuruo, B. Hirst, N. Simmons, 1993, The Journal of biological chemistry.

Expression and localization of monocarboxylate transporters and sodium/proton exchangers in bovine rumen epithelium.

N. Simmons, M. Glanville, C. Graham, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

UT-B is expressed in bovine rumen: potential role in ruminal urea transport.

N. Simmons, T. P. Smith, C. Smith, 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes.

D. Thwaites, B. Hirst, N. Simmons, 1993, The Journal of biological chemistry.

Heterogenous Na+, K+-ATPase expression in the epithelia of rabbit gut-associated lymphoid tissues

B. Hirst, N. Simmons, M. Jepson, 1994, Pflügers Archiv.

Epithelial M cells in the rabbit caecal lymphoid patch display distinctive surface characteristics

B. Hirst, N. Simmons, M. Jepson, 1993, Histochemistry.

Murine Joubert syndrome reveals Hedgehog signaling defects as a potential therapeutic target for nephronophthisis

P. Thelwall, N. Simmons, J. Sayer, 2014, Proceedings of the National Academy of Sciences.

Paracellular barrier and junctional protein distribution depend on basolateral extracellular Ca2+ in cultured epithelia.

B. Hirst, N. Simmons, M. Jepson, 1994, Biochimica et biophysica acta.

Demonstration of protein asymmetries in the plasma membrane of cultured renal (MDCK) epithelial cells by lactoperoxidase‐mediated iodination

N. Simmons, J. Richardson, 1979, FEBS letters.

An Effect of Ca2+ on the Intrinsic Cl−-conductance of Rat Kidney Cortex Brush Border Membrane Vesicles

N. Simmons, S. Vayro, 1996, The Journal of Membrane Biology.

Biochemical and physiological adaptation to chronic propranolol treatment in the rat.

N. Simmons, G. Cramb, N. Griffiths, 1984, Biochemical pharmacology.

The action of ouabain upon chloride secretion in cultured MDCK epithelium.

N. Simmons, 1981, Biochimica et biophysica acta.

Substrate upregulation of the human small intestinal peptide transporter, hPepT1

D. Thwaites, B. Hirst, N. Simmons, 1998, The Journal of physiology.

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

H/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na/H exchanger.

D. Thwaites, N. Simmons, D. Raldúa, 2002, Gastroenterology.

Identification of M cells and their distribution in rabbit intestinal Peyer's patches and appendix

B. Hirst, N. Simmons, G. Hirst, 1993, Cell and Tissue Research.

Electrophysiological and electron‐microscopical correlations with fluid and electrolyte secretion in rabbit ileum.

N. Simmons, R. Naftalin, G. Holman, 1979, The Journal of physiology.

Transepithelial secretion, cellular accumulation and cytotoxicity of vinblastine in defined MDCK cell strains.

B. Hirst, N. Simmons, J. Hunter, 1993, Biochimica et biophysica acta.

Established human renal cell lines: Phenotypic characteristics define suitability for use in in vitro models for predictive toxicology.

N. Simmons, N L Simmons, J A Charlton, 1993, Toxicology in vitro : an international journal published in association with BIBRA.

Factors affecting the compartmentalization of sodium ion within rabbit ileum in vitro.

N. Simmons, R. Naftalin, 1976, Biochimica et biophysica acta.

Identification of two strains of cultured canine renal epithelial cells (MDCK cells) which display entirely different physiological properties.

N. Simmons, N L Simmons, G Barker, 1981, Quarterly journal of experimental physiology.

Bidirectional sodium ion movements via the paracellular and transcellular routes across short-circuited rabbit ileum.

N. Simmons, R. Naftalin, 1976, Biochimica et biophysica acta.

The effects of theophylline and choleragen on sodium and chloride ion movements within isolated rabbit ileum.

N. Simmons, R. Naftalin, 1979, The Journal of physiology.

Transepithelial dipeptide (glycylsarcosine) transport across epithelial monolayers of human Caco-2 cells is rheogenic

D. Thwaites, B. Hirst, N. Simmons, 1993, Pflügers Archiv.

Differential cytotoxicity of Ifosfamide and its metabolites in renal epithelial cell cultures.

N. Simmons, R. Skinner, D. Walker, 1998, Toxicology in vitro : an international journal published in association with BIBRA.

H(+)-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics.

D. Thwaites, B. Hirst, N. Simmons, 1993, Biochimica et biophysica acta.

A role for CBS domain 2 in trafficking of chloride channel CLC-5.

N. Simmons, J. Sayer, G. Carr, 2003, Biochemical and biophysical research communications.

Transepithelial transport of the fluoroquinolone ciprofloxacin by human airway epithelial Calu-3 cells

M. Cavet, N. Simmons, M E Cavet, 1997, Antimicrobial agents and chemotherapy.

Renal secretion of xenobiotics mediated by P-glycoprotein: Importance to renal function in health and exploitation for targeted drug delivery to epithelial cysts in polycystic kidney disease

N. Simmons, M. Jepson, J. Hunter, 1997 .

Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco‐2) cells

M. Cavet, N. Simmons, M E Cavet, 1996, British journal of pharmacology.

Targeted delivery of a substrate for P-glycoprotein to renal cysts in vitro.

N. Simmons, M. Jepson, J. Hunter, 1995, Biochimica et biophysica acta.

Expression and role of sodium, potassium, chloride cotransport (NKCC1) in mouse inner medullary collecting duct (mIMCD-K2) epithelial cells

D. Thwaites, N. Simmons, M. Glanville, 2001, Pflügers Archiv.

Drug Absorption Limited by P-Glycoprotein-Mediated Secretory Drug Transport in Human Intestinal Epithelial Caco-2 Cell Layers

B. Hirst, N. Simmons, J. Hunter, 1993, Pharmaceutical Research.

Gamma‐aminobutyric acid (GABA) transport across human intestinal epithelial (Caco‐2) cell monolayers

D. Thwaites, N. Simmons, L. Basterfield, 2000, British journal of pharmacology.

Junctional uvomorulin/E-cadherin and phosphotyrosine-modified protein content are correlated with paracellular permeability in Madin-Darby canine kidney (MDCK) epithelia

B. Hirst, N. Simmons, M. Jepson, 1994, Histochemistry.

The role of the proton electrochemical gradient in the transepithelial absorption of amino acids by human intestinal Caco-2 cell monolayers

D. Thwaites, N. Simmons, G. McEwan, 1995, The Journal of Membrane Biology.

L-Alanine absorption in human intestinal Caco-2 cells driven by the proton electrochemical gradient

D. Thwaites, B. Hirst, N. Simmons, 1994, The Journal of Membrane Biology.

H(+)/solute-induced intracellular acidification leads to selective activation of apical Na(+)/H(+) exchange in human intestinal epithelial cells.

D. Thwaites, N. Simmons, D. Ford, 1999, The Journal of clinical investigation.

D‐Cycloserine transport in human intestinal epithelial (Caco‐2) cells: mediation by a H + ‐coupled amino acid transporter

D. Thwaites, B. Hirst, N. Simmons, 1995, British journal of pharmacology.

H+-coupled α-methylaminoisobutyric acid transport in human intestinal Caco-2 cells

D. Thwaites, B. Hirst, N. Simmons, 1995 .

H+‐coupled (Na+‐independent) proline transport in human intestinal (Caco‐2) epithelial cell monolayers

D. Thwaites, B. Hirst, N. Simmons, 1993, FEBS letters.

Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells.

B. Hirst, N. Simmons, T. Gray, 1990, Biochemical and biophysical research communications.

Acetylcholine and kinin augmentation of Cl‐ secretion stimulated by prostaglandin in a canine renal epithelial cell line.

N. Simmons, 1992, The Journal of physiology.

The intrinsic Cl–conductance of mouse kidney cortex brush-border membrane vesicles is not related to CFTR

W. Colledge, N. Simmons, N. King, 1997, Pflügers Archiv.

Ca2+ and cAMP‐activated Cl− conductances mediate Cl− secretion in a mouse renal inner medullary collecting duct cell line

N. Simmons, M. Glanville, S. Boese, 2000, The Journal of physiology.

Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+‐dependent Cl− conductance

N. Simmons, M. Glanville, C. Brown, 2000, British journal of pharmacology.

Vasoactive intestinal peptide control of renal adenylate cyclase: in vitro studies of canine renal membranes and cultured canine renal epithelial (MDCK) cells.

N. Simmons, N. Griffiths, E. Rugg, 1989, Quarterly journal of experimental physiology.

Loop-diuretic inhibition of adrenaline-stimulated Cl- secretion in a cultured epithelium of renal origin (MDCK).

N. Simmons, E. Rugg, C. Brown, 1986, Quarterly Journal of Experimental Physiology.

The action of epinephrine on Madin-Darby canine kidney cells.

N. Simmons, E. Rugg, C. Brown, 1984, Federation proceedings.

Epithelial cell volume regulation in hypotonic fluids: studies using a model tissue culture renal epithelial cell system.

N. Simmons, N L Simmons, 1984, Quarterly journal of experimental physiology.

Control of cultured epithelial (MDCK) cell transport function: identification of a beta-adrenoceptor coupled to adenylate cyclase.

N. Simmons, E. Rugg, 1984, Quarterly journal of experimental physiology.

Co-culture of two MDCK strains with distinct junctional protein expression: a model for intercellular junction rearrangement and cell sorting

B. Hirst, N. Simmons, M. Jepson, 1998, Cell and Tissue Research.

Hypo-osmolar stimulation of transepithelial Cl- secretion in cultured human T84 intestinal epithelial layers.

B. Hirst, N. Simmons, G. McEwan, 1992, Biochimica et biophysica acta.

Co-expression of an anion conductance pathway with Na+-glucose cotransport in rat renal brush-border membrane vesicles

N. Simmons, N. King, C. Brown, 1993, Pflügers Archiv.

Cultured monolayers of MDCK cells: a novel model system for the study of epithelial development and function.

N. Simmons, 1982, General pharmacology.

Variations in lectin binding properties of intestinal M cells.

B. Hirst, N. Simmons, M. Jepson, 1995, Journal of drug targeting.

Thyrotropin-Releasing Hormone (TRH) Uptake in Intestinal Brush-Border Membrane Vesicles: Comparison with Proton-Coupled Dipeptide and Na+-Coupled Glucose Transport

D. Thwaites, B. Hirst, N. Simmons, 1993, Pharmaceutical Research.

Passive Transepithelial Absorption of Thyrotropin-Releasing Hormone (TRH) via a Paracellular Route in Cultured Intestinal and Renal Epithelial Cell Lines

D. Thwaites, B. Hirst, N. Simmons, 1993, Pharmaceutical Research.

Substrate specificity of the di/tripeptide transporter in human intestinal epithelia (Caco‐2): identification of substrates that undergo H+‐coupled absorption

D. Thwaites, B. Hirst, N. Simmons, 1994, British journal of pharmacology.

Co-expression of vimentin and cytokeratins in M cells of rabbit intestinal lymphoid follicle-associated epithelium

B. Hirst, N. Simmons, M. Bennett, 2005, The Histochemical Journal.

Microsoft Word-35644277-file00

N. Simmons, J. Wright, T. Coleman, 2011 .

Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco‐2 cell layers

B. Hirst, N. Simmons, N. Griffiths, 1993, British journal of pharmacology.

Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-xL Binding to Bim

Yan Liu, K. Nicolaou, N. Simmons, 2014, Marine drugs.

Urinary Stone Formation: Dent’s Disease Moves Understanding Forward

N. Simmons, J. Sayer, 2002, Nephron Experimental Nephrology.

The voltage‐dependent Cl− channel ClC‐5 and plasma membrane Cl− conductances of mouse renal collecting duct cells (mIMCD‐3)

N. Simmons, J. Sayer, T. Goodship, 2001, The Journal of physiology.

The cellular distribution of oubain-binding sites in monolayer cultures of dog kidney cells [proceedings].

N. Simmons, P. Ogden, J. Lamb, 1978, The Journal of physiology.

Transepithelial vinblastine secretion mediated by P-glycoprotein is inhibited by forskolin derivatives.

B. Hirst, N. Simmons, J. Hunter, 1991, Biochemical and biophysical research communications.

Effect of ouabain upon diuretic-sensitive K+ transport in cultured cells. Evidence for separate modes of operation of the transporter.

N. Simmons, J. Aiton, 1983, Biochimica et biophysica acta.

Na+-independent Lysine Transport in Human Intestinal Caco-2 Cells

D. Thwaites, N. Simmons, D. Markovich, 1996, The Journal of Membrane Biology.

An investigation of [3H]bumetanide uptake in a cultured renal cell line (MDCK).

N. Simmons, D. Tivey, E. Rugg, 1986, Quarterly journal of experimental physiology.

Diuretic action of BTS 39542 (dihydrophthalazin-1-ylacetic acid) is consistent with inhibition of Na + K + Cl cotransport.

N. Simmons, J. Aiton, 1982, Biochemical pharmacology.

Polycation-induced enhancement of epithelial paracellular permeability is independent of tight junctional characteristics.

B. Hirst, N. Simmons, M. Jepson, 1993, Biochimica et biophysica acta.

Voltage Dependence of Transepithelial Guanidine Permeation Across Caco-2 Epithelia Allows Determination of the Paracellular Flux Component

N. Simmons, G. Carr, I. Haslam, 2006, Pharmaceutical Research.

Total synthesis and biological evaluation of marinopyrrole A and analogs

V. Nizet, K. Nicolaou, N. Haste, 2011 .

125I-vasoactive intestinal peptide binding in human kidney.

D. Neal, N. Simmons, B. Charlton, 1991, Mineral and electrolyte metabolism.

Enterocytes in the follicle-associated epithelia of rabbit small intestine display distinctive lectin-binding properties

B. Hirst, N. Simmons, M. Jepson, 1995, Histochemistry and Cell Biology.

Co-expression of vimentin and cytokeratins in M of rabbit intestinal lymphoid follicle-associated epithelium cells

B. Hirst, N. Simmons, M. Bennett, 1992 .

Tissue culture of established renal cell lines.

N. Simmons, N L Simmons, 1990, Methods in enzymology.

Characterisation of volume-activated ion transport across epithelial monolayers of human intestinal T84 cells

B. Hirst, N. Simmons, G. McEwan, 1993, Pflügers Archiv.

Carbachol stimulates Cl- secretion via activation of two distinct apical Cl- pathways in cultured human T84 intestinal epithelial monolayers.

B. Hirst, N. Simmons, G. McEwan, 1994, Biochimica et biophysica acta.

Volume‐activated Cl− secretion and transepithelial vinblastine secretion mediated by P‐glycoprotein are not correlated in cultured human T84 intestinal epithelial layers

B. Hirst, N. Simmons, G. McEwan, 1992, FEBS letters.