A. Tzatsos

发表

Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2017, Nature Communications.

Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation

Alexandros Tzatsos, A. Tzatsos, K. Kandror, 2006, Molecular and Cellular Biology.

Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer.

Weiqun Peng, Yan Kai, A. Tzatsos, 2019, JCI insight.

Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2017, bioRxiv.

Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2018, Cancer cell.

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Wei Zheng, Weiqun Peng, Yan Kai, 2018, Cancer letters.

Raptor Binds the SAIN (Shc and IRS-1 NPXY Binding) Domain of Insulin Receptor Substrate-1 (IRS-1) and Regulates the Phosphorylation of IRS-1 at Ser-636/639 by mTOR*

A. Tzatsos, 2009, The Journal of Biological Chemistry.

Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance

Noel Southall, P. Shinn, Wei Zheng, 2018, Oncogene.

Regulation of the A3 adenosine receptor gene in vascular smooth muscle cells: role of a cAMP and GATA element.

K. Ravid, A. Tzatsos, C. Francis, 2002, Molecular pharmacology.

Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

A. Tzatsos, P. Tsichlis, S. E. Bear, 2008, Proceedings of the National Academy of Sciences.

Energy Depletion Inhibits Phosphatidylinositol 3-Kinase/Akt Signaling and Induces Apoptosis via AMP-activated Protein Kinase-dependent Phosphorylation of IRS-1 at Ser-794*

A. Tzatsos, P. Tsichlis, 2007, Journal of Biological Chemistry.

Ink4a/Arf regulation by let-7b and Hmga2: a genetic pathway governing stem cell aging.

N. Bardeesy, A. Tzatsos, 2008, Cell stem cell.

miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer

Weiqun Peng, Yan Kai, A. Tzatsos, 2018, Oncogene.

KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.

P. Park, Kwok-Kin Wong, P. Trojer, 2013, The Journal of clinical investigation.

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

P. Park, Fatih Ozsolak, D. Scadden, 2011, Nature.

BASIC AND TRANSLATIONAL-PANCREAS

A. Penzo-Méndez, J. Avruch, Dawang Zhou, 2013 .

Histone demethylase KDM 2 B regulates lineage commitment in normal and malignant hematopoiesis

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2019 .

Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis.

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2016, The Journal of clinical investigation.

Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis

A. Tzatsos, S. Thiagalingam, P. Papageorgis, 2015, Breast Cancer Research.

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

P. Park, Fatih Ozsolak, D. Scadden, 2010, Nature.

BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice

Yan Kai, Jaclyn Andricovich, A. Tzatsos, 2020, Nature Communications.

Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells*

Kwok-Kin Wong, N. Bardeesy, A. Tzatsos, 2011, The Journal of Biological Chemistry.

Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis

A. Tzatsos, S. Thiagalingam, P. Papageorgis, 2015, Breast Cancer Research.

Lysine-specific histone demethylases in normal and malignant hematopoiesis.

Yan Kai, Jaclyn Andricovich, A. Tzatsos, 2016, Experimental hematology.

STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

D. Levy, J. Engelman, J. Settleman, 2011, Cancer research.

Predicting CTCF-mediated chromatin interactions by integrating genomic and epigenomic features

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2017, bioRxiv.

Hippo signaling regulates differentiation and maintenance in the exocrine pancreas.

A. Penzo-Méndez, J. Avruch, Dawang Zhou, 2013, Gastroenterology.

Loss of the TGF-β Effector β2SP Promotes Genomic Instability.

A. Rashid, L. Kwong, K. Machida, 2016, Hepatology.

Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus

A. Tzatsos, P. Tsichlis, S. Kampranis, 2009, Proceedings of the National Academy of Sciences.

Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling

Jaclyn Andricovich, A. Tzatsos, R. Wu, 2021, Cell reports.

Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation

Nina M. Muñoz, Ju-Seog Lee, A. Rashid, 2016, Scientific Reports.

Tumor and Stem Cell Biology STAT 3 Plays a Critical Role in KRAS-Induced Pancreatic Tumorigenesis

D. Levy, J. Engelman, J. Settleman, 2011 .

Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes.

A. Tzatsos, K. Kandror, Jianrong Han, 2003, American journal of physiology. Endocrinology and metabolism.

Epigenetic regulation of lineage commitment in normal and malignant hematopoiesis by histone demethylase KDM 2 B

Weiqun Peng, Yan Kai, Jaclyn Andricovich, 2015 .

Loss of the transforming growth factor‐β effector β2‐Spectrin promotes genomic instability

A. Rashid, L. Kwong, K. Machida, 2017, Hepatology.

Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis

A. Tzatsos, S. Thiagalingam, P. Papageorgis, 2015, Breast Cancer Research.

KDM2B controls tumorigenesis in pancreatic cancer via Polycomb-dependent and -independent transcriptional programs

Nabeel, P. Park, P. Trojer, 2012 .

Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

A. Tzatsos, P. Tsichlis, S. E. Bear, 2008, Proceedings of the National Academy of Sciences.