Y. Ishino

发表

Hjc resolvase is a distantly related member of the type II restriction endonuclease family.

H. Toh, H. Daiyasu, K. Komori, 2000, Nucleic acids research.

A Holliday junction resolvase from Pyrococcus furiosus: functional similarity to Escherichia coli RuvC provides evidence for conserved mechanism of homologous recombination in Bacteria, Eukarya, and Archaea.

K. Komori, S. Sakae, Y. Ishino, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A high-density STS map based on a single contig of YAC and P1 clones in the chromosome 8p12-p21 region.

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1997, Genomics.

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

K. Makino, Y. Ishino, H. Shinagawa, 1987, Journal of bacteriology.

New archaeal viruses discovered by metagenomic analysis of viral communities in enrichment cultures.

E. Koonin, Y. Liu, J. Kalinowski, 2019, Environmental microbiology.

X-ray and biochemical anatomy of an archaeal XPF/Rad1/Mus81 family nuclease: similarity between its endonuclease domain and restriction enzymes.

K. Komori, Y. Ishino, K. Morikawa, 2003, Structure.

Segmental Isotope Labeling for Protein NMR Using Peptide Splicing

Toshio Yamazaki, Y. Kyōgoku, Y. Ishino, 1998 .

Practical application of fluorescence-based image analyzer for PCR single-stranded conformation polymorphism analysis used in detection of multiple point mutations.

A. Takahashi-Fujii, Y. Ishino, I. Kato, 1993, PCR methods and applications.

A longer finger-subdomain of family A DNA polymerases found by metagenomic analysis strengthens DNA binding and primer extension abilities.

Y. Kawarabayasi, Y. Ishino, S. Ishino, 2016, Gene.

Cdc6/Orc1 from Pyrococcus furiosus may act as the origin recognition protein and Mcm helicase recruiter

Y. Ishino, F. Matsunaga, M. Akita, 2010, Genes to cells : devoted to molecular & cellular mechanisms.

Dissection of the Regional Roles of the Archaeal Holliday Junction Resolvase Hjc by Structural and Mutational Analyses*

K. Komori, Y. Ishino, K. Morikawa, 2001, The Journal of Biological Chemistry.

Practical applications in molecular biology of sensitive fluorescence detection by a laser-excited fluorescence image analyzer.

M. Homma, Y. Ishino, I. Kato, 1992, BioTechniques.

PI-PfuI and PI-PfuII, intein-coded homing endonucleases from Pyrococcus furiosus. II. Characterization Of the binding and cleavage abilities by site-directed mutagenesis.

K. Komori, Y. Ishino, K. Morikawa, 1999, Nucleic acids research.

A Guanine Nucleotide Exchange Factor for Rab5 Proteins Is Essential for Intracellular Transport of the Proglutelin from the Golgi Apparatus to the Protein Storage Vacuole in Rice Endosperm1[C][W][OA]

Y. Ishino, T. Okita, T. Ueda, 2013, Plant Physiology.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island

F. Robb, P. Forterre, H. Santos, 2017, Extremophiles.

Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease PhoExo I

Y. Ishino, K. Miyazono, Tomoko Ito, 2015, Nucleic acids research.

Mutation of the gene encoding the ribonuclease P RNA in the hyperthermophilic archaeon Thermococcus kodakarensis causes decreased growth rate and impaired processing of tRNA precursors.

M. Kimura, Y. Kawarabayasi, T. Nakashima, 2015, Biochemical and Biophysical Research Communications - BBRC.

Functional role of the C‐terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA

Y. Ishino, T. Miyoshi, T. Uchiumi, 2015, Genes to cells : devoted to molecular & cellular mechanisms.

Mechanisms of Maintaining Genetic Stability by Homologous Recombination

Y. Ishino, K. Morikawa, T. Nishino, 2006 .

The archaeal Hjm helicase has recQ‐like functions, and may be involved in repair of stalled replication fork

Y. Ishino, H. Shinagawa, R. Fujikane, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Enzymatic Switching Between Archaeal DNA Polymerases Facilitates Abasic Site Bypass

Y. Ishino, Q. She, Mingxia Feng, 2021, Frontiers in Microbiology.

A well conserved archaeal B-family polymerase functions as a mismatch and lesion extender

Y. Ishino, Q. She, Mingxia Feng, 2021 .

An optimized Npro-based method for the expression and purification of intrinsically disordered proteins for an NMR study

M. Ota, S. Fukuchi, Y. Ishino, 2015, Intrinsically disordered proteins.

DJ-1 family Maillard deglycases prevent acrylamide formation.

P. Forterre, Y. Ishino, S. Ishino, 2016, Biochemical and biophysical research communications.

Human herpesvirus 6 induces IL‐8 gene expression in human hepatoma cell line, Hep G2

Y. Ishino, R. Inagi, K. Yamanishi, 1996, Journal of medical virology.

Purification and functional characterization of the Glu-tRNA(Gln) amidotransferase from Chlamydomonas reinhardtii.

D. Söll, Y. Ishino, D. Jahn, 1990, The Journal of biological chemistry.

Crystal structure of the archaeal holliday junction resolvase Hjc and implications for DNA recognition.

K. Komori, Y. Ishino, K. Morikawa, 2001, Structure.

The archaeal DNA replication machinery: past, present and future.

Z. Kelman, Y. Ishino, S. Ishino, 2013, Genes & genetic systems.

Cloning of the DNA polymerase gene of Bacillus caldotenax and characterization of the gene product.

Y. Ishino, I. Kato, K. Asada, 1993, Journal of biochemistry.

SOS-inducible DNA polymerase II of E coli is homologous to replicative DNA polymerase of eukaryotes.

Y. Ishino, H. Shinagawa, A. Nakata, 1991, Biochimie.

Guanine nucleotide exchange factor 2 for Rab5 proteins coordinated with GLUP6/GEF regulates the intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm

Y. Ishino, T. Okita, T. Ueda, 2015, Journal of experimental botany.

Aphidicolin inhibits DNA polymerizing activity but not nucleolytic activity of Escherichia coli DNA polymerase II.

Y. Ishino, H. Shinagawa, I. Kato, 1992, Biochimie.

A Novel Biosynthetic Pathway of Archaetidyl-myo-inositol via Archaetidyl-myo-inositol Phosphate from CDP-archaeol and d-Glucose 6-Phosphate in Methanoarchaeon Methanothermobacter thermautotrophicus Cells*

Y. Ishino, H. Morii, Y. Koga, 2009, The Journal of Biological Chemistry.

identification of the gene product. conversion in Escherichia coli, and responsible for alkaline phosphatase isozyme Nucleotide sequence of the iap gene,

K. Makino, Y. Ishino, H. Shinagawa, 2014 .

cDNA cloning of human calpastatin: sequence homology among human, pig, and rabbit calpastatins.

Y. Ishino, M. Maki, K. Asada, 1989, Journal of enzyme inhibition.

Comparative analyses of the two proliferating cell nuclear antigens from the hyperthermophilic archaeon, Thermococcus kodakarensis

H. Daiyasu, Y. Ishino, H. Atomi, 2012, Genes to cells : devoted to molecular & cellular mechanisms.

Studies on the base excision repair (BER) complex in Pyrococcus furiosus.

Y. Ishino, T. Shirai, S. Ishino, 2009, Biochemical Society transactions.

DNA Polymerases BI and D from the Hyperthermophilic Archaeon Pyrococcus furiosus Both Bind to Proliferating Cell Nuclear Antigen with Their C-Terminal PIP-Box Motifs

Y. Ishino, S. Ishino, K. Tori, 2007, Journal of bacteriology.

A single amino acid substitution in the DNA-binding domain of Aeropyrum pernix DNA ligase impairs its interaction with proliferating cell nuclear antigen

Y. Ishino, Shinichi Kiyonari, T. Kamigochi, 2007, Extremophiles.

Specific interactions of three proliferating cell nuclear antigens with replication‐related proteins in Aeropyrum pernix

Y. Kawarabayasi, Y. Ishino, Kenzo Fukunaga, 2007, Molecular microbiology.

The clamp-loading complex for processive DNA replication

Y. Ishino, K. Morikawa, S. Ishino, 2004, Nature Structural &Molecular Biology.

Expression, high-pressure refolding, purification, crystallization and preliminary X-ray analysis of a novel single-strand-specific 3'-5' exonuclease PhoExo I from Pyrococcus horikoshii OT3.

Y. Ishino, K. Miyazono, M. Tanokura, 2014, Acta crystallographica. Section F, Structural biology communications.

Stoichiometric complex formation by proliferating cell nuclear antigen (PCNA) and its interacting protein: purification and crystallization of the DNA polymerase and PCNA monomer mutant complex from Pyrococcus furiosus.

Y. Ishino, K. Morikawa, D. Tsuchiya, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Overexpression, purification and crystallization of an archaeal DNA ligase from Pyrococcus furiosus.

Y. Ishino, K. Morikawa, D. Tsuchiya, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Two Family B DNA Polymerases From Aeropyrum pernix, Based on Revised Translational Frames

Y. Ishino, S. Nagumo, K. Daimon, 2018, Front. Mol. Biosci..

The GINS Complex from Pyrococcus furiosus Stimulates the MCM Helicase Activity*

Y. Ishino, R. Fujikane, F. Matsunaga, 2008, Journal of Biological Chemistry.

Recognition by restriction endonuclease EcoRI of deoxyoctanucleotides containing modified sugar moieties.

Y. Ishino, E. Ohtsuka, M. Ikehara, 1984, European journal of biochemistry.

Expression and molecular characterization of spherical particles derived from the genome of the hyperthermophilic euryarchaeote Pyrococcus furiosus.

E. Yamashita, T. Tsukihara, Y. Ishino, 2005, Journal of biochemistry.

Biochemical and genetical analyses of the three mcm genes from the hyperthermophilic archaeon, Thermococcus kodakarensis

H. Daiyasu, Y. Ishino, H. Atomi, 2011, Genes to cells : devoted to molecular & cellular mechanisms.

Identification of a Novel Binding Motif in Pyrococcus furiosus DNA Ligase for the Functional Interaction with Proliferating Cell Nuclear Antigen*

Y. Ishino, K. Takayama, H. Nishida, 2006, Journal of Biological Chemistry.

The GINS complex from the thermophilic archaeon, Thermoplasma acidophilum may function as a homotetramer in DNA replication

Y. Ishino, A. Yamagishi, N. Birkeland, 2011, Extremophiles.

Control of enzyme reaction by a designed metal-ion-dependent α-helical coiled-coil protein

Y. Ishino, S. Ishino, Toshiki Tanaka, 2012, JBIC Journal of Biological Inorganic Chemistry.

The replication machinery of LUCA: common origin of DNA replication and transcription

E. Koonin, Y. Ishino, M. Krupovic, 2020, BMC Biology.

Escherichia coli DNA polymerase II is homologous to α-like DNA polymerases

H. Toh, Y. Ishino, H. Shinagawa, 1991, Molecular and General Genetics MGG.

Crystal structure and functional implications of Pyrococcus furiosus hef helicase domain involved in branched DNA processing.

K. Komori, Y. Ishino, K. Morikawa, 2005, Structure.

From Structure-Function Analyses to Protein Engineering for Practical Applications of DNA Ligase

Y. Ishino, Maiko Tanabe, H. Nishida, 2015, Archaea.

History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology

P. Forterre, Y. Ishino, M. Krupovic, 2018, Journal of bacteriology.

Archaeal DNA Polymerase-B as a DNA Template Guardian: Links between Polymerases and Base/Alternative Excision Repair Enzymes in Handling the Deaminated Bases Uracil and Hypoxanthine

Y. Ishino, B. Connolly, S. Ishino, 2016, Archaea.

A Well-Conserved Archaeal B-Family Polymerase Functions as an Extender in Translesion Synthesis

Y. Ishino, Q. She, Mingxia Feng, 2022, mBio.

DNA repair in hyperthermophilic and hyperradioresistant microorganisms.

Y. Ishino, I. Narumi, 2015, Current opinion in microbiology.

DNA polymerases as useful reagents for biotechnology – the history of developmental research in the field

Y. Ishino, S. Ishino, Yoshizumi Ishino, 2014, Front. Microbiol..

Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea

Y. Ishino, T. Shirai, S. Ishino, 2016, Nucleic acids research.

Archaeal DNA replication: identifying the pieces to solve a puzzle.

Y. Ishino, I. Cann, Isaac K. O. Cann, 1999, Genetics.

In vivo interactions of archaeal Cdc6/Orc1 and minichromosome maintenance proteins with the replication origin

P. Forterre, Y. Ishino, H. Myllykallio, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

D. Kohda, Y. Ishino, K. Morikawa, 2020, BMC biology.

Studies on DNA-related enzymes to elucidate molecular mechanisms underlying genetic information processing and their application in genetic engineering

Y. Ishino, 2020, Bioscience, biotechnology, and biochemistry.

Fluorescent labeling of a DNA sequencing primer.

Y. Ishino, I. Kato, J. Mineno, 1993, DNA sequence : the journal of DNA sequencing and mapping.

The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG

Y. Ishino, I. Cann, S. Ishino, 2018, Scientific Reports.

Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.

Y. Ishino, H. Shinagawa, Yoshino Kubota, 2004, Genes & development.

DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen

Y. Ishino, T. Shirai, S. Ishino, 2021, Nucleic acids research.

Structural basis for substrate recognition and processive cleavage mechanisms of the trimeric exonuclease

Y. Ishino, K. Miyazono, Tomoko Ito, 2015 .

Structure-specific DNA nucleases: structural basis for 3D-scissors.

Y. Ishino, K. Morikawa, T. Nishino, 2006, Current opinion in structural biology.

Organization and nucleotide sequence of the DNA polymerase gene from the archaeon Pyrococcus furiosus.

H. Toh, Y. Ishino, I. Kato, 1993, Nucleic acids research.

Overproduction of Thermus aquaticus DNA polymerase and its structural analysis by ion-spray mass spectrometry.

M. Miyagi, Y. Ishino, I. Kato, 1994, Journal of biochemistry.

Metagenomic analysis provides functional insights into seasonal change of a non-cyanobacterial prokaryotic community in temperate coastal waters

M. Hattori, T. Gojobori, K. Ikeo, 2021, PloS one.

A Preliminary Metagenome Analysis Based on a Combination of Protein Domains

T. Gojobori, S. Watabe, S. Mitsuyama, 2019, Proteomes.

Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease.

Y. Ishino, A. Hijikata, T. Tsuji, 2016, Structure.

Replication protein A complex in Thermococcus kodakarensis interacts with DNA polymerases and helps their effective strand synthesis

Y. Ishino, S. Ishino, T. Yamagami, 2019, Bioscience, biotechnology, and biochemistry.

Biochemical characterization of endonuclease V from the hyperthermophilic archaeon, Pyrococcus furiosus.

Y. Ishino, S. Ishino, Yuriko Egashira, 2014, Journal of biochemistry.

The Endo V homologue from the hyperthermophilic euryarchaeon , Pyrococcus furiosus ( PfuEndoV

Y. Ishino, S. Ishino, Yuriko Egashira, 2014 .

Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus

Y. Ishino, T. Shirai, S. Iwai, 2009, Nucleic acids research.

Crystal structure of the novel lesion-specific endonuclease PfuEndoQ from Pyrococcus furiosus

Y. Ishino, K. Miyazono, Tomoko Ito, 2018, Nucleic acids research.

A functional endonuclease Q exists in the bacterial domain: identification and characterization of endonuclease Q from Bacillus pumilus

Y. Ishino, I. Cann, S. Ishino, 2017, Bioscience, biotechnology, and biochemistry.

PCNA is involved in the EndoQ-mediated DNA repair process in Thermococcales

Y. Ishino, I. Cann, Kotaro Yoshida, 2016, Scientific Reports.

EndoQ and EndoV work individually for damaged DNA base repair in Pyrococcus furiosus.

Y. Ishino, S. Ishino, T. Yamagami, 2015, Biochimie.

A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus

Y. Ishino, S. Ishino, T. Yamagami, 2015, Nucleic acids research.

Physical and Functional Interactions between Uracil-DNA Glycosylase and Proliferating Cell Nuclear Antigen from the Euryarchaeon Pyrococcus furiosus*

Y. Ishino, T. Shirai, Shinichi Kiyonari, 2008, Journal of Biological Chemistry.

Biochemical characterization of the hjc holliday junction resolvase of Pyrococcus furiosus.

K. Komori, S. Sakae, Y. Ishino, 2000, Nucleic acids research.

Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication

Y. Ishino, H. Myllykallio, Hanae Kudo, 2018, Nucleic acids research.

Genetic analysis of DNA repair in the hyperthermophilic archaeon, Thermococcus kodakaraensis.

P. Forterre, Y. Ishino, R. Fujikane, 2010, Genes & genetic systems.

Structural and functional analyses of an archaeal XPF/Rad1/Mus81 nuclease: asymmetric DNA binding and cleavage mechanisms.

K. Komori, Y. Ishino, K. Morikawa, 2005, Structure.

Both RadA and RadB Are Involved in Homologous Recombination inPyrococcus furiosus *

J. DiRuggiero, K. Komori, Y. Ishino, 2000, The Journal of Biological Chemistry.

Localized melting of duplex DNA by Cdc6/Orc1 at the DNA replication origin in the hyperthermophilic archaeon Pyrococcus furiosus

Y. Ishino, F. Matsunaga, M. Akita, 2009, Extremophiles.

Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm

Y. Ishino, K. Morikawa, T. Shirai, 2009, BMC Structural Biology.

The closed structure of an archaeal DNA ligase from Pyrococcus furiosus.

Y. Ishino, K. Morikawa, H. Nishida, 2006, Journal of molecular biology.

Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp.

P. Forterre, A. Glatigny, Y. Ishino, 2007, Nucleic acids research.

Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex

D. Kohda, Y. Ishino, K. Morikawa, 2011, Proceedings of the National Academy of Sciences.

Identification and characterization of Thermus thermophilus HB8 RuvA protein, the subunit of the RuvAB protein complex that promotes branch migration of Holliday junctions.

Y. Ishino, H. Shinagawa, S. Kuramitsu, 2000, Genes & genetic systems.

Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations

Y. Ishino, T. Uchiumi, K. Maruyama, 2019, Scientific Reports.

Comparing PCR-generated artifacts of different polymerases for improved accuracy of DNA metabarcoding

Y. Ishino, S. Nagai, Sirje Sildever, 2022, Metabarcoding and Metagenomics.

Cooperation of the N-terminal Helicase and C-terminal Endonuclease Activities of Archaeal Hef Protein in Processing Stalled Replication Forks*

K. Komori, Y. Ishino, H. Shinagawa, 2004, Journal of Biological Chemistry.

Architectures of archaeal GINS complexes, essential DNA replication initiation factors

Y. Ishino, K. Morikawa, T. Shirai, 2011, BMC Biology.

Two Family B DNA Polymerases from Aeropyrum pernix, an Aerobic Hyperthermophilic Crenarchaeote

Y. Ishino, N. Nomura, Y. Sako, 1999, Journal of bacteriology.

A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase.

H. Toh, K. Komori, Y. Ishino, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Atomic structure of the clamp loader small subunit from Pyrococcus furiosus.

Y. Ishino, K. Morikawa, I. Cann, 2001, Molecular cell.

Three-dimensional electron microscopy of the clamp loader small subunit from Pyrococcus furiosus.

Y. Ishino, K. Morikawa, T. Oyama, 2001, Journal of structural biology.

The RecJ2 protein in the thermophilic archaeon Thermoplasma acidophilum is a 3′-5′ exonuclease that associates with a DNA replication complex

D. Kohda, Y. Ishino, S. Ishino, 2017, The Journal of Biological Chemistry.

Disordered interdomain region of Gins is important for functional tetramer formation to stimulate MCM helicase in Thermoplasma acidophilum

D. Kohda, Y. Ishino, S. Ishino, 2015, Bioscience, biotechnology, and biochemistry.

Activation of the MCM helicase from the thermophilic archaeon, Thermoplasma acidophilum by interactions with GINS and Cdc6-2

D. Kohda, Y. Ishino, N. Birkeland, 2014, Extremophiles.

DNA Replication in Archaea, the Third Domain of Life

Y. Ishino, S. Ishino, 2013 .

Rapid progress of DNA replication studies in Archaea, the third domain of life

Y. Ishino, S. Ishino, 2012, Science China Life Sciences.

Comprehensive Search for DNA Polymerase in the Hyperthermophilic Archaeon, Pyrococcus furiosus

Y. Ishino, S. Ishino, 2006, Nucleosides, nucleotides & nucleic acids.

Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA

Y. Ishino, K. Morikawa, S. Ishino, 2003, Protein science : a publication of the Protein Society.

Mutational analysis of Pyrococcus furiosus replication factor C based on the three-dimensional structure

Y. Ishino, K. Morikawa, S. Ishino, 2003, Extremophiles.

Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus

Y. Ishino, K. Morikawa, S. Ishino, 2002, Genes to cells : devoted to molecular & cellular mechanisms.

Novel endonuclease in Archaea cleaving DNA with various branched structure.

K. Komori, Y. Ishino, H. Shinagawa, 2002, Genes & genetic systems.

Three Proliferating Cell Nuclear Antigen-Like Proteins Found in the Hyperthermophilic Archaeon Aeropyrum pernix: Interactions with the Two DNA Polymerases

Y. Kawarabayasi, H. Kikuchi, Y. Ishino, 2002, Journal of bacteriology.

The Archaeal DNA Primase

D. Kohda, K. Komori, Y. Ishino, 2001, The Journal of Biological Chemistry.

Functional interactions of an archaeal sliding clamp with mammalian clamp loader and DNA polymerase δ

Y. Ishino, I. Cann, T. Tsurimoto, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Biochemical Analysis of Replication Factor C from the Hyperthermophilic Archaeon Pyrococcus furiosus

H. Toh, H. Daiyasu, Y. Ishino, 2001, Journal of bacteriology.

Archaeal primase bridging the gap between RNA and DNA polymerases

D. Kohda, K. Komori, Y. Ishino, 2001, Current Biology.

K. Komori, Y. Ishino, I. Cann, 1997 .

New insights into the diversity and evolution of the archaeal mobilome from three complete genomes of Saccharolobus shibatae.

J. Kalinowski, Y. Ishino, K. Severinov, 2021, Environmental microbiology.

Amino acid sequence motifs essential to 3'-->5' exonuclease activity of Escherichia coli DNA polymerase II.

Y. Ishino, H. Shinagawa, I. Kato, 1994, The Journal of biological chemistry.

Nucleotide sequence of the lig gene and primary structure of DNA ligase of Escherichia coli

K. Makino, Y. Ishino, H. Shinagawa, 1986, Molecular and General Genetics MGG.

A Novel Type of Polyhedral Viruses Infecting Hyperthermophilic Archaea

Y. Liu, Y. Ishino, M. Krupovic, 2017, Journal of Virology.

Inspiration and encounters: Carl Woese and my 30‐year research journey

Y. Ishino, 2022, mLife.

Pol B, a Family B DNA Polymerase, in Thermococcus kodakarensis is Important for DNA Repair, but not DNA Replication

Y. Ishino, S. Fujiwara, T. Imanaka, 2019, Microbes and environments.

Expansion of the zinc metallo‐hydrolase family of the β‐lactamase fold

Hiromi Daiyasu, H. Toh, H. Daiyasu, 2001 .

Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication

Y. Ishino, T. Shirai, M. Kusunoki, 2016, Nucleic acids research.

Replication Protein A in Pyrococcus furiosus Is Involved in Homologous DNA Recombination*

K. Komori, Y. Ishino, 2001, The Journal of Biological Chemistry.

A tRNA(Glu) gene from the hyperthermophilic archaeon Pyrococcus furiosus contains the 3'-terminal CCA sequence of the mature tRNA.

Y. Ishino, I. Cann, 1998, FEMS microbiology letters.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island

F. Robb, P. Forterre, H. Santos, 2017, Extremophiles.

Identification of a Novel Helicase Activity Unwinding Branched DNAs from the Hyperthermophilic Archaeon, Pyrococcus furiosus*

K. Komori, Y. Ishino, H. Shinagawa, 2005, Journal of Biological Chemistry.

Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome

Y. Ishino, S. Ishino, T. Oyama, 2021, Nucleic acids research.

Title Possible function of the second RecJ-like protein in stalledreplication fork repair by interacting with Hef

Y. Ishino, H. Atomi, T. Kanai, 2019 .

Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef

Y. Ishino, H. Atomi, T. Kanai, 2017, Scientific Reports.

The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis

Y. Ishino, H. Atomi, T. Kanai, 2017, Nucleic acids research.

DNA polymerases from euryarchaeota.

Y. Ishino, S. Ishino, 2001, Methods in enzymology.

Splicing of the Mycobacteriophage Bethlehem DnaB Intein

Shmuel Pietrokovski, Francine B. Perler, Margaret A. Johnson, 2009, The Journal of Biological Chemistry.

Crystal structure of an archaeal intein-encoded homing endonuclease PI-PfuI.

K Morikawa, K. Komori, Y. Ishino, 2000, Journal of molecular biology.

Functional Interactions of a Homolog of Proliferating Cell Nuclear Antigen with DNA Polymerases inArchaea

H. Toh, K. Komori, Y. Ishino, 1999, Journal of bacteriology.

Mechanism of replication machinery assembly as revealed by the DNA ligase–PCNA–DNA complex architecture

Y. Ishino, K. Morikawa, T. Shirai, 2009, Proceedings of the National Academy of Sciences.

Application of environmental DNA resources to create useful DNA polymerases with different properties

Y. Ishino, S. Ishino, 2012 .

Rapid and practical detection of beta-globin mutations causing beta-thalassemia by fluorescence-based PCR-single-stranded conformation polymorphism analysis.

A. Takahashi-Fujii, Y. Ishino, Y. Fukumaki, 1994, Molecular and cellular probes.

The replication machinery of LUCA: common origin of DNA replication and transcription

E. Koonin, Y. Ishino, M. Krupovic, 2020, BMC Biology.

Escherichia coli DNA polymerase II is homologous to alpha-like DNA polymerases.

H. Toh, Y. Ishino, H. Shinagawa, 1991, Molecular & general genetics : MGG.

Open clamp structure in the clamp-loading complex visualized by electron microscopic image analysis.

Hirofumi Suzuki, Y. Ishino, K. Morikawa, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure of an archaeal DNA sliding clamp: Proliferating cell nuclear antigen from Pyrococcus furiosus

Y. Ishino, K. Morikawa, S. Matsumiya, 2001, Protein science : a publication of the Protein Society.

Molecular Analyses of a Three-Subunit Euryarchaeal Clamp Loader Complex from Methanosarcina acetivorans

R. Mackie, Y. Ishino, I. Cann, 2009, Journal of bacteriology.

Mutational Analysis of the Pyrococcus furiosusHolliday Junction Resolvase Hjc Revealed Functionally Important Residues for Dimer Formation, Junction DNA Binding, and Cleavage Activities*

H. Toh, H. Daiyasu, K. Komori, 2000, The Journal of Biological Chemistry.

Identification of the critical region in replication factor C from Pyrococcus furiosus for the stable complex formation with proliferating cell nuclear antigen and DNA.

Tomoko Miyata, Y. Ishino, K. Morikawa, 2005, Genes & genetic systems.

Reverse-chaperoning activity of an AAA+ protein.

K. Dahmen, T. Ha, Y. Ishino, 2011, Biophysical journal.

The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases

H. Doi, Y. Ishino, I. Kato, 1995, Journal of bacteriology.

Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity

A. Nishi, Y. Ishino, R. Fujikane, 2022, Communications Biology.

Inhibition of respiratory syncytial virus infectivity by Ephedrae Herba and Cinnamomi Cortex through interaction with G glycoprotein

A. Nishi, Y. Ishino, R. Fujikane, 2021 .

The OsGEN-L protein from Oryza sativa possesses Holliday junction resolvase activity as well as 5'-flap endonuclease activity.

Y. Ishino, H. Satoh, S. Ishino, 2012, Journal of biochemistry.

The euryarchaeotes, a subdomain of Archaea, survive on a single DNA polymerase: fact or farce?

Y. Ishino, I. Cann, 1998, Genes & genetic systems.

Physiological Responses of the Hyperthermophilic Archaeon “Pyrococcus abyssi” to DNA Damage Caused by Ionizing Radiation

Patrick Forterre, P. Forterre, Y. Ishino, 2003, Journal of bacteriology.

Expansion of the zinc metallo-hydrolase family of the beta-lactamase fold.

H Toh, H. Toh, H. Daiyasu, 2001, FEBS letters.

Genetic and Biochemical Characterizations of aLhr1 Helicase in the Thermophilic Crenarchaeon Sulfolobus acidocaldarius

S. Matsumoto, Y. Ishino, N. Kurosawa, 2021, Catalysts.

Specific interaction between DNA polymerase II (PolD) and RadB, a Rad51/Dmc1 homolog, in Pyrococcus furiosus.

Y. Ishino, K. Morikawa, I. Hayashi, 1999, Nucleic acids research.

Structure‐Based Mutational Study of an Archaeal DNA Ligase towards Improvement of Ligation Activity

Y. Ishino, K. Morikawa, M. Yohda, 2012, Chembiochem : a European journal of chemical biology.

A Novel Single-Strand Specific 3′–5′ Exonuclease Found in the Hyperthermophilic Archaeon, Pyrococcus furiosus

Y. Ishino, S. Ishino, K. Tori, 2013, PloS one.

Molecular analyses of an unusual translesion DNA polymerase from Methanosarcina acetivorans C2A.

S. Koike, R. Mackie, Y. Ishino, 2010, Journal of molecular biology.

Role of RadA and DNA Polymerases in Recombination-Associated DNA Synthesis in Hyperthermophilic Archaea

Y. Ishino, S. Ishino, R. Dulermo, 2020, Biomolecules.

A novel DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus: gene cloning, expression, and characterization

H. Doi, Y. Ishino, I. Kato, 1997, Genes to cells : devoted to molecular & cellular mechanisms.

Novel inhibition of archaeal family-D DNA polymerase by uracil

Y. Ishino, G. Henneke, B. Connolly, 2013, Nucleic acids research.

Elucidating functions of DP1 and DP2 subunits from the Thermococcus kodakarensis family D DNA polymerase

Y. Ishino, S. Ishino, T. Yamagami, 2018, Extremophiles.

DNA polymerases and DNA ligases

Y. Ishino, S. Ishino, 2013 .

Adenylosuccinate synthetase genes: molecular cloning and phylogenetic analysis of a highly conserved archaeal gene.

H. Toh, Y. Ishino, I. Cann, 1998, Systematic and applied microbiology.

Mutations of Asp540 and the domain‐connecting residues synergistically enhance Pyrococcus furiosus DNA ligase activity

Y. Ishino, Maiko Tanabe, S. Ishino, 2014, FEBS letters.

Investigation of the clamp loading mechanism from biochemical and 3D structural perspectives

Hirofumi Suzuki, Y. Ishino, K. Morikawa, 2007 .

Mechanism to Load the Clamp onto DNA: Seeing Vivid Structures by Single Particle Analysis

Hirofumi Suzuki, Y. Ishino, K. Morikawa, 2006 .

Exonuclease processivity of archaeal replicative DNA polymerase in association with PCNA is expedited by mismatches in DNA

Y. Ishino, T. Tsuji, T. Shirai, 2016, Scientific Reports.

Mutant Taq DNA polymerases with improved elongation ability as a useful reagent for genetic engineering

Y. Kawarabayasi, Y. Ishino, S. Ishino, 2014, Frontiers in Microbiology.

A useful strategy to construct DNA polymerases with different properties by using genetic resources from environmental DNA.

Y. Kawarabayasi, Y. Ishino, T. Yamagami, 2009, Genes & genetic systems.

DNA polymerases BI and D , from the hyperthermophilic archaeon , 1 Pyrococcus furiosus , both bind to PCNA with their C-terminal PIP box 2 motifs

Y. Ishino, S. Ishino, K. Tori, 2007 .

A Non-α-like DNA Polymerase from the Hyperthermophilic Archaeon Pyrococcus furiosus

Y. Ishino, I. Kato, T. Uemori, 1995 .

Mechanisms of maintaining genetic stability by homologous recombination.

Y. Ishino, K. Morikawa, T. Nishino, 2006, Chemical reviews.

Coupling factor F1 ATPase with defective beta subunit from a mutant of Escherichia coli.

Y. Ishino, M. Futai, H. Kanazawa, 1980, Journal of biochemistry.

A novel Streptomyces restriction endonuclease, Sse1825I, cleaving at 5'-GG/GWCCC-3'.

Y. Ishino, I. Kato, F. Kimizuka, 1995, Gene.

Rapid and reliable DNA sequencing with a dideoxy sequencing kit.

Y. Ishino, 1992, American biotechnology laboratory.

The Hyperthermophilic Archaeon Pyrodictium occultum Has Two (cid:97) -Like DNA Polymerases

H. Doi, Y. Ishino, I. Kato, 1995 .

Multiple Interactions of the Intrinsically Disordered Region between the Helicase and Nuclease Domains of the Archaeal Hef Protein*

Tetsuya Mori, T. Ando, N. Kodera, 2014, The Journal of Biological Chemistry.

PI-PfuI and PI-PfuII, intein-coded homing endonucleases from Pyrococcus furiosus. I. Purification and identification of the homing-type endonuclease activities.

N. Fujita, K. Komori, Y. Ishino, 1999, Nucleic acids research.

Activation of the MCM helicase from the thermophilic archaeon, Thermoplasma acidophilum by interactions with GINS and Cdc6-2

D. Kohda, Y. Ishino, N. Birkeland, 2014, Extremophiles.

Rapid and practical detection of β-globin mutation causing β-thalassemia by fluorescence-based PCR-single-stranded conformation polymorphism analysis

A. Takahashi-Fujii, Y. Ishino, Y. Fukumaki, 1994 .

Development of a time-series shotgun metagenomics database for monitoring microbial communities at the Pacific coast of Japan

Yutaka Suzuki, T. Gojobori, K. Ikeo, 2021, Scientific Reports.

Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity

A. Nishi, Y. Ishino, R. Fujikane, 2022, Communications biology.

Rapid progress of DNA replication studies in Archaea, the third domain of life

Y. Ishino, S. Ishino, 2012, Science China Life Sciences.

Application of PCNA to processive PCR by reducing the stability of its ring structure

Y. Ishino, S. Ishino, A. Kawamura, 2012 .

Biophysical analysis of PCNA from Pyrococcus furiosus

Y. Ishino, S. Ishino, A. Kuwamura, 2012 .

A non-alpha-like DNA polymerase from the hyperthermophilic archaeon Pyrococcus furiosus.

Y. Ishino, I. Kato, T. Uemori, 1995, Biological & pharmaceutical bulletin.

Six dinucleotide repeat polymorphisms on chromosome 7

T. Ogihara, N. Niikawa, A. Takahashi-Fujii, 1994, Japanese Journal of Human Genetics.

Molecular Mechanism of Stalled Replication Fork Repair—From Archaea to Human Genetic Disorder—

Y. Ishino, 2008 .

Dinucleotide repeat polymorphism at the D8S1055

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1994, The Japanese Journal of Human Genetics.

The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG

Y. Ishino, I. Cann, S. Ishino, 2018, Scientific Reports.

Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex

Y. Ishino, K. Morikawa, T. Oyama, 2009, Proceedings of the National Academy of Sciences.

Direct visualization of DNA baton pass between replication factors bound to PCNA

D. Kohda, Y. Ishino, K. Morikawa, 2018, Scientific Reports.

Dinucleotide repeat polymorphism at the D8S1053

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1994, Japanese Journal of Human Genetics.

Dinucleotide repeat polymorphism at the D8S1054

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1995, Japanese Journal of Human Genetics.

Preferential replication-dependent mutagenesis in the lagging DNA strand inEscherichia coli

H. Doi, M. Furusawa, Y. Ishino, 1996, Molecular and General Genetics MGG.

Functional interdependence of DNA polymerizing and 3'-->5' exonucleolytic activities in Pyrococcus furiosus DNA polymerase I.

K. Komori, Y. Ishino, 2000, Protein engineering.