J. Widrick

发表

Treadmill validation of an over-ground walking test to predict peak oxygen consumption

C. Ebbeling, J. Widrick, A. Ward, 2004, European Journal of Applied Physiology and Occupational Physiology.

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

George M. Church, Ru Xiao, Le Cong, 2016, Science.

Development of a single-stage submaximal treadmill walking test.

E. Puleo, C. Ebbeling, J. Widrick, 1991, Medicine and science in sports and exercise.

Muscle Mechanics: Adaptations with Exercise‐Training

R. Fitts, J. Widrick, 1996, Exercise and sport sciences reviews.

Whole Body Periodic Acceleration Is an Effective Therapy to Ameliorate Muscular Dystrophy in mdx Mice

J. Widrick, P. Allen, Jose A. Adams, 2014, PloS one.

Effect of intermittent weight bearing on soleus fiber force-velocity-power and force-pCa relationships.

R. Fitts, J. Widrick, J. J. Bangart, 1997, Journal of applied physiology.

limbs during very short efforts in humans Effects of microgravity on maximal power of lower

P. Zamparo, C. Capelli, D. Felsenberg, 2015 .

Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight.

R. Fitts, D. Costill, D. Riley, 2000, Journal of applied physiology.

Antioxidants did not prevent muscle damage in response to an ultramarathon run.

J. Widrick, M. Traber, A. Mastaloudis, 2006, Medicine and science in sports and exercise.

Relative effects of exercise training and alendronate treatment on skeletal muscle function of ovariectomized rats

J. Widrick, C. Snow, G. Maddalozzo, 2007, Menopause.

Dystrophic muscle improvement in zebrafish via increased heme oxygenase signaling.

M. Gasperini, L. Kunkel, J. Widrick, 2014, Human molecular genetics.

Alcohol alters whole body composition, inhibits bone formation, and increases bone marrow adiposity in rats

J. Widrick, C. Rosen, R. Turner, 2009, Osteoporosis International.

An open source microcontroller based flume for evaluating swimming performance of larval, juvenile, and adult zebrafish

B. Sanchez, A. Beggs, L. Kunkel, 2018, PloS one.

depolarization after eccentric contractions Stretch-activated ion channels contribute to membrane

J. Widrick, J. Semmler, B. Stockert, 2015 .

Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease

A. Grinberg, J. Widrick, R. Suragani, 2019, Scientific Reports.

Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species

A. Wagers, P. Sabeti, A. Beggs, 2021, Cell.

Dry-land resistance training for competitive swimming.

D. Costill, J. Widrick, H. Tanaka, 1993, Medicine and science in sports and exercise.

The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice

T. van Groen, L. Kunkel, J. Widrick, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Time of day effects on sympathoadrenal and pressor reactivity to exercise in healthy men

M. Vukovich, D. Costill, J. Widrick, 2004, European Journal of Applied Physiology and Occupational Physiology.

Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function

J. Widrick, F. Villa, E. Gussoni, 2020, Skeletal muscle.

Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model

J. Widrick, P. Agrawal, J. Laporte, 2022, JCI insight.

Effects of drink carbonation on the gastric emptying characteristics of water and flavored water.

D. Costill, J. Widrick, G. McConell, 1991, International journal of sport nutrition.

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome

E. Lai, J. Widrick, Michael A. Lopez, 2022, Life Science Alliance.

SPEG-deficient skeletal muscles exhibit abnormal triad and defective calcium handling

A. Beggs, J. Widrick, C. Pierson, 2018, Human molecular genetics.

Effect of 17 days of bed rest on peak isometric force and unloaded shortening velocity of human soleus fibers.

R. Fitts, D. Costill, D. Riley, 1997, The American journal of physiology.

Individual and combined effects of exercise and alendronate on bone mass and strength in ovariectomized rats.

J. Widrick, K. Winters-Stone, C. Snow, 2007, Bone.

Reduced Training Volume and Intensity Maintain Aerobic Capacity but not Performance in Distance Runners

D. Costill, Hirofumi Tanaka, J. Widrick, 1993, International journal of sports medicine.

hindlimb muscles and under altered loading conditions PGAM-M expression is regulated pretranslationally in

R. Fitts, S. Swoap, D. Riley, 2015 .

Effect of a 17 day spaceflight on contractile properties of human soleus muscle fibres

D A Riley, R. Fitts, D. Costill, 1999, The Journal of physiology.

MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.

Jamie L. Marshall, L. Kunkel, M. Gasperini, 2014, The Journal of clinical investigation.

Review: Microgravity and skeletal muscle Invited Physiology of a Microgravity Environment

J. West, B. Levine, J. Widrick, 2015 .

Microgravity and skeletal muscle Invited Review : Physiology of a Microgravity Environment

R. Fitts, J. Widrick, D. Riley, 2000 .

Peak power of muscles injured by lengthening contractions

J. Widrick, T. Barker, 2006, Muscle & nerve.

Physiology of a microgravity environment invited review: microgravity and skeletal muscle.

R. Fitts, J. Widrick, R H Fitts, 2000, Journal of applied physiology.

Concurrent muscle and bone deterioration in a murine model of cancer cachexia

J. Widrick, Kadir Carruthers, L. Morse, 2013, Physiological reports.

Thin filament diversity and physiological properties of fast and slow fiber types in astronaut leg muscles.

R. Fitts, D. Costill, D. Riley, 2002, Journal of applied physiology.

Disproportionate loss of thin filaments in human soleus muscle after 17‐day bed rest

R. Fitts, D. Costill, D. Riley, 1998, Muscle & nerve.

Effect of 17 days of bed rest on peak isometric force and unloaded shortening velocity of human soleus fibers.

R. Fitts, D. Costill, D. Riley, 1997, American journal of physiology. Cell physiology.

Enzyme replacement therapy rescues weakness and improves muscle pathology in mice with X-linked myotubular myopathy.

R. Grange, A. Beggs, J. Widrick, 2013, Human molecular genetics.

Transgenic zebrafish model of DUX4 misexpression reveals a developmental role in FSHD pathogenesis

L. Kunkel, J. Widrick, F. Rahimov, 2018, Human molecular genetics.

miR-486 is an epigenetic modulator of Duchenne muscular dystrophy pathologies

E. Lai, J. Widrick, Michael A. Lopez, 2021, bioRxiv.

Eccentric contraction-induced injury to type I, IIa, and IIa/IIx muscle fibers of elderly adults

W. Frontera, R. Fielding, J. Widrick, 2012, AGE.

Discovery of Novel Therapeutics for Muscular Dystrophies using Zebrafish Phenotypic Screens

A. Beggs, L. Kunkel, J. Widrick, 2019, Journal of neuromuscular diseases.

Passive force and viscoelastic properties of single fibers in human aging muscles

W. Frontera, J. Widrick, E. Phillips, 2019, European Journal of Applied Physiology.

Force-velocity-power and force-pCa relationships of human soleus fibers after 17 days of bed rest.

R. Fitts, D. Costill, M. Karhanek, 1998, Journal of applied physiology.

IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism

N. Houstis, J. Avruch, L. Minichiello, 2019, Molecular and Cellular Biology.

Menopause and the Musculoskeletal System

J. Widrick, L. Morse, R. Battaglino, 2013 .

PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA

J. Spinazzola, L. Kunkel, J. Widrick, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Calcium-activated force of human muscle fibers following a standardized eccentric contraction.

J. Widrick, Seung-Jun Choi, 2010, American journal of physiology. Cell physiology.

RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes

L. Zon, A. Chakraborty, A. Beggs, 2018, PLoS Genetics.

Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy.

B. Sanchez, A. Beggs, L. Kunkel, 2016, Physiological genomics.

An octaguanidine–morpholino oligo conjugate improves muscle function of mdx mice

J. Widrick, P. Morcos, Shan Jiang, 2011, Muscle & nerve.

A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies.

L. Kunkel, J. Widrick, A. Lek, 2018, JCI insight.

depress myofibrillar force in murine skeletal muscle acts via TNFR1 and muscle-derived oxidants to

K. Campbell, J. Widrick, J. Moylan, 2015 .

Functional and structural adaptations of skeletal muscle to microgravity.

R. Fitts, J. Widrick, R H Fitts, 2001, The Journal of experimental biology.

Isometric force and maximal shortening velocity of single muscle fibers from elite master runners.

R. Fitts, D. Costill, J. Widrick, 1996, The American journal of physiology.

Cardiorespiratory responses to physical work during and following 17 days of bed rest and spaceflight.

Robert Fitts, R. Fitts, D. Costill, 2006, Journal of applied physiology.

Soleus fiber force and maximal shortening velocity after non-weight bearing with intermittent activity.

R. Fitts, M. Karhanek, J. Widrick, 1996, Journal of applied physiology.

Combined effects of fatigue and eccentric damage on muscle power.

J. Widrick, Seung-Jun Choi, 2009, Journal of applied physiology.

Functional properties of human muscle fibers after short-term resistance exercise training.

J. Widrick, T. Shoepe, J. Stelzer, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Force-velocity and force-power properties of single muscle fibers from elite master runners and sedentary men.

R. Fitts, D. Costill, J. Widrick, 1996, The American journal of physiology.

Aerobic Capacity With Hybrid FES Rowing in Spinal Cord Injury: Comparison With Arms‐Only Exercise and Preliminary Findings With Regular Training

J. Widrick, J Andrew Taylor, Jeffrey J Widrick, 2011, PM & R : the journal of injury, function, and rehabilitation.

Detrimental effects of reloading recovery on force, shortening velocity, and power of soleus muscles from hindlimb-unloaded rats.

J. Widrick, R. Turner, U. Iwaniec, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Economy and preferred speed of walking in adults with and without Down syndrome.

M. Pavol, S. Agiovlasitis, J. Widrick, 2009, Adapted physical activity quarterly : APAQ.

highlighted topics Physiology of a Microgravity Environment Invited Review: Microgravity and skeletal muscle

R. Fitts, J. Widrick, D. Riley, 2000 .

Spaceflight effects on single skeletal muscle fiber function in the rhesus monkey.

R. Fitts, J. Widrick, D. Desplanches, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

Peak force and maximal shortening velocity of soleus fibers after non-weight-bearing and resistance exercise.

R. Fitts, J. Widrick, 1997, Journal of applied physiology.

Functional adaptability of muscle fibers to long-term resistance exercise.

J. Widrick, T. Shoepe, J. Stelzer, 2003, Medicine and science in sports and exercise.

DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism

J. Widrick, Adrienne Samani, Yimin Wang, 2023, bioRxiv.

Time course of glycogen accumulation after eccentric exercise.

D. Costill, J. Widrick, G. McConell, 1992, Journal of applied physiology.

Morphological and functional characteristics of skeletal muscle fibers from hormone-replaced and nonreplaced postmenopausal women.

J. Widrick, B. Valentine, C. Snow, 2003, The journals of gerontology. Series A, Biological sciences and medical sciences.

Electrical impedance myography detects age-related skeletal muscle atrophy in adult zebrafish

S. Rutkove, J. Nagy, J. Widrick, 2023, Scientific reports.

Evaluation of Electrical Impedance as a Biomarker of Myostatin Inhibition in Wild Type and Muscular Dystrophy Mice

Benjamin Sanchez, Seward B. Rutkove, Adam Pacheck, 2015, PloS one.

Effect of P(i) on unloaded shortening velocity of slow and fast mammalian muscle fibers.

J. Widrick, 2002, American journal of physiology. Cell physiology.

Velocity, force, power, and Ca2+ sensitivity of fast and slow monkey skeletal muscle fibers.

R. Fitts, J. Widrick, S. Bodine, 1998, Journal of applied physiology.

Cross‐bridge mechanisms of muscle weakness in multiple sclerosis

J. Widrick, D. Garner, 2003, Muscle & nerve.

Day to Day Variation in Time Trial Cycling Performance

Hirofumi Tanaka, David L. Costill, D. Costill, 1992, International journal of sports medicine.

Comparison of a space shuttle flight (STS-78) and bed rest on human muscle function.

R. Fitts, D. Costill, J. Widrick, 2001, Journal of applied physiology.

The effects of hormone replacement therapy and resistance training on spine bone mineral density in early postmenopausal women.

Mark A Hoffman, J. Widrick, B. Cardinal, 2007, Bone.

Optimizing assays of zebrafish larvae swimming performance for drug discovery

A. Beggs, L. Kunkel, J. Widrick, 2023, Expert opinion on drug discovery.

Lack of neuromuscular origins of adaptation after a long-term stretching program.

J. Widrick, R. Harter, Charlie Hicks-Little, 2012, Journal of sport rehabilitation.

Carbohydrate feedings and exercise performance: effect of initial muscle glycogen concentration.

D. Costill, Hirofumi Tanaka, J. Widrick, 1993, Journal of applied physiology.

Substrate and enzyme profile of fast and slow skeletal muscle fibers in rhesus monkeys.

R. Fitts, J. Widrick, V. Grichko, 1999, Journal of applied physiology.

Unilateral lower limb suspension does not mimic bed rest or spaceflight effects on human muscle fiber function.

R. Fitts, D. Costill, D. Riley, 2002, Journal of applied physiology.

Intersession reliability of Hoffmann reflex gain and presynaptic inhibition in the human soleus muscle.

J. Widrick, R. Harter, Charlie Hicks-Little, 2009, Archives of physical medicine and rehabilitation.

Morphological and functional characteristics of skeletal muscle Morphological and functional characteristics of skeletal muscle fibers from hormone-replaced and nonreplaced postmenopausal fibers from hormone-replaced and nonreplaced postmenopausal women women

J. Widrick, B. Valentine, C. Snow, 2022 .

Functional properties of slow and fast gastrocnemius muscle fibers after a 17-day spaceflight.

R. Fitts, D. Costill, D. Riley, 2001, Journal of applied physiology.

Whole-body vibration slows the acquisition of fat in mature female rats

J. Widrick, C. Rosen, R. Turner, 2008, International Journal of Obesity.

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

G. Ravenscroft, J. Widrick, Steve Carr, 2022, bioRxiv.

Effect of hindlimb suspension on the functional properties of slow and fast soleus fibers from three strains of mice.

J. Widrick, J. Stelzer, Julian E Stelzer, 2003, Journal of applied physiology.

MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.

Jamie L. Marshall, L. Kunkel, M. Gasperini, 2014, The Journal of clinical investigation.

Gait characteristics of adults with Down syndrome explain their greater metabolic rate during walking.

M. Pavol, S. Agiovlasitis, J. Widrick, 2015, Gait & posture.

Force-velocity-power and force-pCa relationships of human soleus fibers after 17 days of bed rest.

R. Fitts, D. Costill, J. Widrick, 1998, Journal of applied physiology.

Functional and structural adaptations of skeletal muscle to microgravity

R. Fitts, J. Widrick, Danny R. Riley, 2022 .